Detailed information for compound 651787

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 396.524 | Formula: C27H28N2O
  • H donors: 1 H acceptors: 1 LogP: 5.56 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ccc(cc1)C1C2=C(O)CC(CC2=Nc2c1c1ccccc1cc2)(C)C)C
  • InChi: 1S/C27H28N2O/c1-27(2)15-22-26(23(30)16-27)24(18-9-12-19(13-10-18)29(3)4)25-20-8-6-5-7-17(20)11-14-21(25)28-22/h5-14,24,30H,15-16H2,1-4H3
  • InChiKey: UIHOUPMNAKIJSU-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0092 0.024 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.2736 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0092 0.024 0.0237
Schistosoma mansoni steroid hormone receptor ad4bp 0.0059 0.0124 0.0121
Echinococcus granulosus allatostatin A receptor 0.0092 0.024 0.0237
Trypanosoma brucei PAB1-binding protein , putative 0.0086 0.0217 0.0881
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0091 0.0234 0.0231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Schistosoma mansoni hypothetical protein 0.0092 0.024 0.0237
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.005 0.009 0.0087
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0453 0.1517 0.1514
Schistosoma mansoni hypothetical protein 0.0092 0.024 0.0237
Echinococcus multilocularis neuropeptide receptor 0.0092 0.024 0.0237
Schistosoma mansoni GTP-binding protein alpha subunit 0.0028 0.0012 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0234 0.0952
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0091 0.0236 0.0862
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0066 0.0147 0.0799
Schistosoma mansoni amine GPCR 0.0092 0.024 0.0237
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0049 0.0087 0.0654
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0453 0.1517 0.1514
Mycobacterium tuberculosis Conserved hypothetical protein 0.0375 0.124 0.6316
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0143 0.042 1
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0058 0.0119 0.0233
Schistosoma mansoni lipoxygenase 0.009 0.0231 0.0228
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0007 0.0111
Echinococcus granulosus multidrug resistance protein 1 0.0055 0.0108 0.0105
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0025 0.0003 0.0011
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0009 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0091 0.0236 0.0233
Echinococcus granulosus lamin 0.0058 0.0119 0.0116
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Schistosoma mansoni adenoreceptor 0.0092 0.024 0.0237
Trichomonas vaginalis taga, putative 0.0055 0.0108 0.0394
Schistosoma mansoni inositol monophosphatase 0.0034 0.0036 0.0033
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0034 0.0063
Brugia malayi beta-lactamase 0.0091 0.0234 0.0464
Echinococcus multilocularis inositol monophosphatase 1 0.0034 0.0036 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0049 0.0087 0.0413
Mycobacterium leprae Conserved hypothetical protein 0.0049 0.0087 0.0944
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0108 0.0394
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0038 0.0049 0.0092
Trichomonas vaginalis D-aminoacylase, putative 0.0091 0.0234 0.0856
Entamoeba histolytica hypothetical protein 0.0064 0.0141 0.4124
Entamoeba histolytica ABC transporter, putative 0.0029 0.0017 0.0404
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0028 0.0012 0.0017
Giardia lamblia NADH oxidase lateral transfer candidate 0.0037 0.0043 0.0903
Brugia malayi MH1 domain containing protein 0.0028 0.0013 0.0021
Loa Loa (eye worm) nuclear hormone receptor 0.0028 0.0013 0.002
Echinococcus granulosus multidrug resistance associated protein 1 0.0029 0.0017 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0645 0.2195 0.4405
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2631 0.9219 0.9219
Schistosoma mansoni lipoxygenase 0.0063 0.0135 0.0132
Echinococcus multilocularis ATP binding cassette sub family B 0.0054 0.0105 0.0102
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.012 0.0337 0.0672
Trichomonas vaginalis inositol monophosphatase, putative 0.0034 0.0036 0.0131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0092 0.024 0.0237
Echinococcus granulosus survival motor neuron protein 1 0.0221 0.0694 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0337 0.1106 0.4539
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0027 0.0008 0.0007
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0108 0.0105
Echinococcus granulosus lysosomal alpha glucosidase 0.0114 0.0315 0.0313
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.033 0.1081 1
Onchocerca volvulus Bile acid receptor homolog 0.0059 0.0124 0.0665
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0049 0.0087 0.0413
Brugia malayi nuclear receptor NHR-88 0.0028 0.0013 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0182 0.0359
Plasmodium falciparum ataxin-2 like protein, putative 0.0086 0.0217 0.5128
Brugia malayi Serotonin receptor 0.0092 0.024 0.0477
Entamoeba histolytica ATP-binding cassette protein, putative 0.0029 0.0017 0.0404
Schistosoma mansoni bromodomain containing protein 0.0064 0.0139 0.0136
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0027 0.01
Echinococcus granulosus G protein coupled receptor 139 0.0092 0.024 0.0237
Giardia lamblia MRP-like ABC transporter 0.0029 0.0017 0.0073
Entamoeba histolytica G protein alpha subunit, putative 0.0028 0.0012 0.0259
Echinococcus granulosus ecdysone induced protein 78C 0.0059 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0143 0.042 0.0418
Onchocerca volvulus 0.0092 0.024 0.1328
Echinococcus granulosus cytochrome P450 2K1 0.0049 0.0087 0.0084
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0028 0.0012 0.0043
Leishmania major extracellular receptor, putative 0.0066 0.0147 0.0594
Echinococcus granulosus Smad4 0.0028 0.0013 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0643 0.219 0.4395
Echinococcus multilocularis chromobox protein 1 0.0047 0.0082 0.0079
Echinococcus granulosus chromobox protein 1 0.0047 0.0082 0.0079
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0143 0.042 0.0418
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Echinococcus granulosus mitogen activated protein kinase 3 0.0038 0.0049 0.0046
Giardia lamblia Multidrug resistance-associated protein 1 0.0029 0.0017 0.0073
Brugia malayi cytochrome P450 0.0049 0.0087 0.017
Loa Loa (eye worm) TYRA-2 protein 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0108 0.0394
Schistosoma mansoni thyroid hormone receptor 0.0206 0.0643 0.0641
Onchocerca volvulus 0.0129 0.037 0.2062
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0128 0.0125
Trichomonas vaginalis sucrase-isomaltase, putative 0.0025 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0054 0.0105 0.0206
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0034 0.0034 0.0031
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0031 0.0025 0.0044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0036 0.0131
Plasmodium vivax importin-beta 2, putative 0.0048 0.0083 0.1167
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0034 0.0031
Echinococcus multilocularis dnaJ subfamily B 0.2851 1 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.01 0.0268 0.1091
Toxoplasma gondii HEAT repeat-containing protein 0.0048 0.0083 0.0634
Echinococcus multilocularis zinc finger protein 0.0028 0.0011 0.0008
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0221 0.0694 0.1389
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0057 0.0115 0.0225
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Schistosoma mansoni hypothetical protein 0.0049 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0059 0.0124 0.0243
Echinococcus granulosus neuropeptide receptor A26 0.153 0.5325 0.5324
Brugia malayi isocitrate dehydrogenase 0.0143 0.042 0.0839
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0028 0.0012 0.0009
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0015 0.0048
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.024 0.0237
Brugia malayi RNA, U transporter 1 0.0136 0.0394 0.0786
Echinococcus multilocularis muscleblind protein 0.0229 0.0725 0.0722
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0129 0.037 0.0736
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.024 0.0477
Schistosoma mansoni glutamate receptor NMDA 0.1312 0.4554 0.4553
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0036 0.0042 0.0099
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0643 0.219 0.4395
Brugia malayi Heterochromatin protein 1 0.0047 0.0082 0.0158
Echinococcus granulosus orexin receptor type 2 0.0092 0.024 0.0237
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0059 0.0112
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0044
Echinococcus granulosus nmda type glutamate receptor 0.1576 0.5488 0.5487
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0049 0.0087 0.0413
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0049 0.0087 0.0654
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0092 0.024 0.0237
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0091 0.0234 0.0464
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0029 0.0017 0.0056
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0059 0.0124 0.0243
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0034 0.0031
Echinococcus multilocularis lysosomal alpha glucosidase 0.0114 0.0315 0.0313
Echinococcus granulosus L aminoadipate semialdehyde 0.0129 0.037 0.0367
Brugia malayi Steroid receptor seven-up type 2 0.0059 0.0124 0.0243
Brugia malayi Smad1 0.0028 0.0013 0.0021
Loa Loa (eye worm) glutathione reductase 0.0106 0.0287 0.0572
Echinococcus multilocularis serotonin receptor 0.0092 0.024 0.0237
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0082 0.0299
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0037 0.0043 0.0081
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0091 0.0234 0.1164
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0712 0.2432 1
Brugia malayi neuropeptide F receptor 0.0092 0.024 0.0477
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi Ets-domain containing protein 0.0076 0.0184 0.0363
Brugia malayi Bromodomain containing protein 0.0032 0.0025 0.0045
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0092 0.024 0.0237
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0003 0.0011
Trypanosoma brucei importin beta-1 subunit, putative 0.0048 0.0083 0.0329
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0013 0.001
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0066 0.0147 0.029
Echinococcus multilocularis peptidase Clp (S14 family) 0.0043 0.0067 0.0064
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.024 0.0237
Echinococcus granulosus muscleblind protein 0.0229 0.0725 0.0722
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0059 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Entamoeba histolytica hypothetical protein 0.0064 0.0141 0.4124
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0042 0.0413
Schistosoma mansoni biogenic amine receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Schistosoma mansoni transcription factor LCR-F1 0.0064 0.0141 0.0138
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.0184 0.0363
Schistosoma mansoni smad1 5 8 and 0.0028 0.0013 0.001
Brugia malayi hypothetical protein 0.0028 0.0012 0.0017
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0038 0.0049 0.0189
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0143 0.042 0.1719
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0195 0.0603 0.06
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0798 0.2736 0.5492
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0059 0.0124 0.0243
Loa Loa (eye worm) hypothetical protein 0.0091 0.0234 0.0464
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.024 0.0237
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0028 0.0012 0.0017
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0037 0.0043 0.0251
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0044
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0108 0.0105
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0092 0.024 0.0237
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0034 0.0034 0.0031
Echinococcus multilocularis GPCR, family 2 0.0453 0.1517 0.1514
Schistosoma mansoni ap endonuclease 0.012 0.0337 0.0335
Echinococcus granulosus beta LACTamase domain containing family member 0.0091 0.0234 0.0231
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0029 0.0017 0.0056
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.024 0.0237
Echinococcus granulosus snurportin 1 0.051 0.1718 0.1715
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Brugia malayi nuclear receptor RXR 0.0028 0.0013 0.002
Loa Loa (eye worm) glutamate receptor 1 0.0129 0.0369 0.0736
Brugia malayi Nuclear hormone receptor-like 1 0.0059 0.0124 0.0243
Schistosoma mansoni multidrug resistance protein 0.0029 0.0017 0.0014
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0028 0.0012 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0013 0.001
Schistosoma mansoni hypothetical protein 0.0129 0.0369 0.0366
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1432 0.4979 1
Echinococcus multilocularis cpg binding protein 0.0213 0.0668 0.0665
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0092 0.024 0.0237
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.024 0.0237
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0092 0.024 0.0477
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0053 0.0101 0.0098
Mycobacterium leprae putative cytochrome p450 0.0049 0.0087 0.0944
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0029 0.0017 0.0056
Schistosoma mansoni smad1 5 8 and 0.0028 0.0013 0.001
Leishmania major cytochrome p450-like protein 0.0049 0.0087 0.0347
Loa Loa (eye worm) hypothetical protein 0.0066 0.0148 0.0291
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni neuropeptide receptor 0.0092 0.024 0.0237
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0365 0.0362
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0129 0.0369 0.0366
Trypanosoma cruzi cytochrome P450, putative 0.0076 0.0182 0.0735
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0365 0.0362
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0092 0.024 0.0237
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0119 0.0233
Schistosoma mansoni hypothetical protein 0.2851 1 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0234 0.0464
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0108 0.0105
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni inositol monophosphatase 0.0034 0.0036 0.0033
Echinococcus multilocularis fmrfamide receptor 0.0092 0.024 0.0237
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0034 0.0034 0.0031
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0029 0.0017 0.0056
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0108 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0049 0.0087 0.0413
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni multidrug resistance protein 0.0029 0.0017 0.0014
Trypanosoma brucei DNA polymerase beta thumb, putative 0.01 0.0268 0.1091
Echinococcus granulosus thyroid hormone receptor alpha 0.0028 0.0013 0.001
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0049 0.0087 0.0654
Trichomonas vaginalis D-aminoacylase, putative 0.0091 0.0234 0.0856
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.012 0.0337 0.1377
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni glutamate receptor AMPA 0.0129 0.0369 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Schistosoma mansoni intermediate filament proteins 0.0058 0.0119 0.0116
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0013 0.001
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0049 0.0087 0.0654
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0453 0.1517 0.1514
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0028 0.0012 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Plasmodium falciparum importin beta, putative 0.0048 0.0083 0.1913
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus GTP binding nuclear protein Ran 0.0035 0.0038 0.0035
Brugia malayi Inositol-1 0.0034 0.0036 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0007
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0042 0.0155
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0066 0.0148 0.0145
Brugia malayi putative neuropeptide receptor 0.0092 0.024 0.0477
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Schistosoma mansoni opsin-like receptor 0.0092 0.024 0.0237
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0028 0.0012 0.0009
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.012 0.0337 1
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Echinococcus multilocularis glutamate receptor NMDA 0.1117 0.3866 0.3864
Loa Loa (eye worm) hypothetical protein 0.0045 0.0072 0.0139
Echinococcus multilocularis receptor type guanylyl cyclase 0.0066 0.0147 0.0144
Echinococcus granulosus alpha 1A adrenergic receptor 0.0092 0.024 0.0237
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0022 0.0019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0013 0.001
Entamoeba histolytica hypothetical protein 0.0066 0.0147 0.4316
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0042 0.0161
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0643 0.219 0.2188
Brugia malayi Calcitonin receptor-like protein seb-1 0.1432 0.4979 1
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0119 0.0233
Brugia malayi orphan nuclear receptor NR2E1 0.0028 0.0013 0.002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0059 0.0124 0.0243
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) MH2 domain-containing protein 0.0413 0.1373 0.2754
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0092 0.024 0.0477
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0066 0.0147 0.029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0028 0.0012 0.0017
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0143 0.042 0.0418
Echinococcus granulosus tar DNA binding protein 0.0128 0.0365 0.0362
Echinococcus multilocularis serotonin receptor 0.0092 0.024 0.0237
Schistosoma mansoni multidrug resistance protein 0.0055 0.0108 0.0105
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0092 0.024 0.0237
Schistosoma mansoni aldehyde dehydrogenase 0.0187 0.0577 0.0574
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0045 0.0084
Loa Loa (eye worm) hypothetical protein 0.1432 0.4979 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0049 0.0087 0.0413
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.024 0.0237
Trichomonas vaginalis ap endonuclease, putative 0.012 0.0337 0.1233
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0052 0.0096 0.0093
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0037 0.0043 0.004
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0049 0.0087 0.0413
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0034 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0049 0.0087 0.0413
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0234 0.5125
Entamoeba histolytica multidrug resistance protein, putative 0.0029 0.0017 0.0404
Loa Loa (eye worm) hypothetical protein 0.0055 0.0108 0.0211
Echinococcus granulosus glutamate receptor subunit protein glur 0.0129 0.0369 0.0366
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0082 0.0299
Toxoplasma gondii NADPH-glutathione reductase 0.0037 0.0043 0.032
Brugia malayi G protein-coupled receptor 0.0092 0.024 0.0477
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0072 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0365 0.0362
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0049 0.0087 0.0413
Echinococcus granulosus tachykinin peptides receptor 99D 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Brugia malayi ecdysone receptor 0.0028 0.0013 0.002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0113 0.0313 0.1144
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0337 0.1106 0.4539
Leishmania major ABC-thiol transporter 0.0029 0.0017 0.0056
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0124 0.0121
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0034 0.0031
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0049 0.0087 0.0413
Echinococcus granulosus nuclear receptor nhr 48 0.0028 0.0013 0.001
Mycobacterium ulcerans hypothetical protein 0.0375 0.124 1
Schistosoma mansoni protein kinase 0.0066 0.0147 0.0144
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.002 0.0017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0365 0.0728
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0059 0.0124 0.0121
Entamoeba histolytica P-glycoprotein-5 0.0055 0.0108 0.3133
Brugia malayi MH2 domain containing protein 0.0413 0.1373 0.2754
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0036 0.0042 0.0935
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0049 0.0087 0.0654
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0031 0.0023 0.0083
Echinococcus multilocularis Smad4 0.0028 0.0013 0.001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0037 0.0043 0.032
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0129 0.0369 0.0366
Echinococcus multilocularis importin subunit beta 1 0.0048 0.0083 0.008
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0049 0.0087 0.0654
Echinococcus granulosus lamin dm0 0.0058 0.0119 0.0116
Echinococcus granulosus mixed lineage leukemia protein mll 0.005 0.009 0.0087
Toxoplasma gondii hypothetical protein 0.0115 0.032 0.2517
Trypanosoma brucei p-glycoprotein 0.0029 0.0017 0.0056
Brugia malayi Probable ClpP-like protease 0.0066 0.0148 0.0291
Echinococcus multilocularis NMDA receptor 0.0129 0.0369 0.0366
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.033 0.1081 0.871
Schistosoma mansoni importin beta-1 0.0048 0.0083 0.008
Echinococcus multilocularis nmda type glutamate receptor 0.1183 0.4099 0.4097
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus multilocularis lamin 0.0058 0.0119 0.0116
Leishmania major pentamidine resistance protein 1 0.0029 0.0017 0.0056
Mycobacterium tuberculosis Probable dehydrogenase 0.0241 0.0766 0.3888
Brugia malayi Cytochrome P450 family protein 0.0076 0.0182 0.0359
Brugia malayi AKH receptor 0.0092 0.024 0.0477
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0187 0.0577 0.0574
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.012 0.0337 0.0335
Trypanosoma brucei multidrug resistance protein E 0.0029 0.0017 0.0056
Toxoplasma gondii ABC1 family protein 0.0091 0.0234 0.1835
Echinococcus multilocularis g protein coupled receptor 0.0092 0.024 0.0237
Echinococcus multilocularis mixed lineage leukemia protein mll 0.005 0.009 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Leishmania major p-glycoprotein e 0.0029 0.0017 0.0056
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0049 0.0087 0.0654
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0028 0.0013 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.0092 0.024 0.0477
Brugia malayi hypothetical protein 0.0086 0.0217 0.043
Brugia malayi Cytochrome P450 family protein 0.0049 0.0087 0.017
Schistosoma mansoni multidrug resistance protein 0.0029 0.0017 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0206 0.0643 0.0641
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0241 0.0766 0.3888
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0143 0.042 0.0418
Schistosoma mansoni hypothetical protein 0.0979 0.3377 0.3375
Echinococcus multilocularis neuropeptide receptor A26 0.153 0.5325 0.5324
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.2736 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0092 0.024 0.0237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0059 0.0124 0.0243
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0459 0.1537 0.1534
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.024 0.0237
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.012 0.0337 0.7828
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0092 0.024 0.0237
Schistosoma mansoni neuropeptide receptor 0.0092 0.024 0.0237
Onchocerca volvulus Neuropeptide F receptor homolog 0.0092 0.024 0.1328
Trichomonas vaginalis penicillin-binding protein, putative 0.0091 0.0234 0.0856
Schistosoma mansoni multidrug resistance protein 0.0055 0.0108 0.0105
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0049 0.0179
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0053 0.0101 0.0403
Schistosoma mansoni glutamate receptor NMDA 0.0129 0.0369 0.0366
Brugia malayi TAR-binding protein 0.0128 0.0365 0.0728
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0013 0.002
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.024 0.0237
Echinococcus granulosus mothers against decapentaplegic 5 0.0028 0.0013 0.001
Echinococcus multilocularis multidrug resistance associated protein 1 0.0029 0.0017 0.0014
Echinococcus granulosus expressed protein 0.0028 0.0012 0.0009
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0268 0.0861 1
Schistosoma mansoni hypothetical protein 0.0045 0.0073 0.007
Schistosoma mansoni hypothetical protein 0.0064 0.0141 0.0138
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0187 0.0577 0.2363
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0761 0.2607 0.2605
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0028 0.0012 0.0043
Schistosoma mansoni ran 0.0035 0.0038 0.0035
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0063
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0052 0.0096 0.0725
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0013 0.001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.024 0.0237
Onchocerca volvulus 0.0092 0.024 0.1328
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0053 0.0102 0.0372
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0059 0.0124 0.0665
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0036 0.0131
Brugia malayi nuclear hormone receptor 0.0028 0.0013 0.002
Mycobacterium tuberculosis Probable hydrolase 0.0091 0.0234 0.1164
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.0577 0.4624
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0049 0.0087 0.0654
Echinococcus multilocularis multidrug resistance associated protein 7 0.0029 0.0017 0.0014
Brugia malayi nuclear receptor RXR 0.0031 0.0025 0.0044
Brugia malayi nuclear hormone receptor family member nhr-6 0.0028 0.0013 0.002
Schistosoma mansoni cpg binding protein 0.02 0.0622 0.0619
Schistosoma mansoni thyroid hormone receptor 0.0206 0.0643 0.0641
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0037 0.0043 0.004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0034 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.0577 0.4624
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0028 0.0012 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0091 0.0236 0.0233
Brugia malayi Isocitrate dehydrogenase 0.0143 0.042 0.0839
Schistosoma mansoni smad 0.0028 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0144 0.0423 0.0844
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0066 0.0148 0.0145
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0043 0.0067 0.0708
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0029 0.0017 0.0027
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0049 0.0087 0.0654
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0055 0.0108 0.0431
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0025 0.0003 0.0001
Echinococcus granulosus voltage gated potassium channel 0.0045 0.0072 0.0069
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0059 0.0124 0.0121
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0007 0.0015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0036 0.0135
Trichomonas vaginalis esterase, putative 0.0091 0.0234 0.0856
Trypanosoma cruzi PAB1-binding protein , putative 0.0086 0.0217 0.0881
Echinococcus multilocularis orexin receptor type 2 0.0092 0.024 0.0237
Schistosoma mansoni multidrug resistance protein 0.0029 0.0017 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0049 0.0087 0.0413
Onchocerca volvulus 0.0055 0.0108 0.0574
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.1144
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0038 0.0049 0.0189
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0003 0.0011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0108 0.0394
Echinococcus multilocularis G-protein coupled receptor, putative 0.0092 0.024 0.0237
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0643 0.219 0.2188
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0049 0.0087 0.0347
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0035 0.0038 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0059 0.0124 0.0243
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0034 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0028 0.0012 0.0009
Schistosoma mansoni myosin xvIII 0.0092 0.024 0.0237
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0066 0.0147 0.029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.0124 0.0243
Trypanosoma cruzi importin beta-1 subunit, putative 0.0039 0.0051 0.0197
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0037 0.0043 0.0166
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0017
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0096 0.0187
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0143 0.042 0.0418
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0049 0.0087 0.0413
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi hypothetical protein 0.0144 0.0423 0.0844
Brugia malayi hypothetical protein 0.0055 0.011 0.0214
Schistosoma mansoni ATP-binding cassette transporter 0.0129 0.0372 0.0369
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0037 0.0043 0.0166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Echinococcus granulosus fmrfamide receptor 0.0092 0.024 0.0237
Brugia malayi F/Y-rich N-terminus family protein 0.0069 0.0159 0.0313
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0128 0.0366 0.0729
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0049 0.0046
Schistosoma mansoni myst-related protein 0.0025 0.0003 0.000000076607
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0037 0.0043 0.0013
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0028 0.0012 0.0017
Giardia lamblia Multidrug resistance-associated protein 1 0.0029 0.0017 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0059 0.0124 0.0243
Brugia malayi Cytochrome P450 family protein 0.0197 0.061 0.1221
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0028 0.0012 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0236 0.0862
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.024 0.0237
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0128 0.0366 0.0363
Trypanosoma brucei protein kinase, putative 0.0038 0.0049 0.0189
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.0124 0.0243
Echinococcus multilocularis smad 0.0028 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0017
Schistosoma mansoni nuclear receptor 0.0028 0.0013 0.001
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0028 0.0012 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0016 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0049 0.0087 0.0413
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0128 0.0366 0.0729
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0092 0.024 0.0237
Echinococcus granulosus multidrug resistance protein 1 0.0055 0.0108 0.0105
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.024 0.0237
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0059 0.0124 0.0121
Onchocerca volvulus 0.0092 0.024 0.1328
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0035 0.0038 0.0145
Brugia malayi jmjC domain containing protein 0.0065 0.0144 0.0283
Schistosoma mansoni retinoic acid receptor RXR 0.0059 0.0124 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0049 0.0179
Brugia malayi Metabotropic glutamate receptor precursor. 0.0066 0.0147 0.029
Brugia malayi latrophilin 2 splice variant baaae 0.0979 0.3377 0.6779
Schistosoma mansoni zinc finger protein 0.0028 0.0011 0.0008
Leishmania major phosphopantetheinyl transferase-like protein 0.0036 0.0042 0.0161
Brugia malayi neuropeptide F receptor 0.0092 0.024 0.0477
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0124 0.0121
Echinococcus multilocularis G protein coupled receptor 139 0.0092 0.024 0.0237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0059 0.0124 0.0243
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0091 0.0236 0.0958
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0059 0.0124 0.0121
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0038 0.0049 0.0189
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0045 0.0042
Echinococcus multilocularis neuropeptide receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) inositol-1 0.0034 0.0036 0.0066
Brugia malayi Importin beta-1 subunit 0.0048 0.0083 0.016
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0034 0.0031
Brugia malayi jmjC domain containing protein 0.0037 0.0045 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0102 0.0372
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0028 0.0012 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0027 0.01
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0195 0.0603 0.06
Schistosoma mansoni aldehyde dehydrogenase 0.0187 0.0577 0.0574
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0055 0.0108 0.0211
Onchocerca volvulus 0.0092 0.024 0.1328
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0007 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0091 0.0236 0.0468
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0092 0.024 0.0237
Onchocerca volvulus 0.0058 0.0119 0.0637
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0129 0.0369 0.0366
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0037 0.0043 0.0297
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0049 0.0087 0.0347
Schistosoma mansoni glutamate receptor kainate 0.0129 0.0369 0.0366
Echinococcus granulosus receptor type guanylyl cyclase 0.0066 0.0147 0.0144
Echinococcus granulosus multidrug resistance protein 1 0.0055 0.0108 0.0105
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0055 0.0108 0.0517
Echinococcus multilocularis ecdysone induced protein 78C 0.0059 0.0124 0.0121
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0113 0.0313 0.1144
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis glutamate receptor 2 0.0129 0.0369 0.0366
Echinococcus granulosus somatostatin receptor 0.0092 0.024 0.0237
Echinococcus multilocularis FTZ F1 alpha 0.0059 0.0124 0.0121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0643 0.219 0.2188
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0102 0.0372
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0092 0.024 0.0237
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.347
Plasmodium falciparum thioredoxin reductase 0.0037 0.0043 0.0966
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0012
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0037 0.0043 0.004
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0049 0.0087 0.0413
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.0184 0.0181
Loa Loa (eye worm) hypothetical protein 0.0065 0.0144 0.0284
Schistosoma mansoni myst-related protein 0.0025 0.0003 0.000000076607
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.024 0.0237
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0143 0.042 0.1719
Brugia malayi MH1 domain containing protein 0.0028 0.0013 0.0021
Echinococcus multilocularis multidrug resistance protein 1 0.0055 0.0108 0.0105
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0028 0.0013 0.001
Echinococcus multilocularis snurportin 1 0.051 0.1718 0.1715
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0066 0.0147 0.0144
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0007 0.0015
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Echinococcus granulosus TGF beta signal transducer SmadC 0.0028 0.0013 0.001
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0108 0.0105
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Loa Loa (eye worm) nuclear receptor NHR-67 0.0028 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0013 0.001
Brugia malayi Dopamine receptor 0.0092 0.024 0.0477
Onchocerca volvulus 0.0092 0.024 0.1328
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Plasmodium falciparum glutathione reductase 0.0037 0.0043 0.0966
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0055 0.0108 0.0633
Brugia malayi Ets-domain containing protein 0.0076 0.0184 0.0363
Brugia malayi Glycosyl hydrolases family 31 protein 0.0114 0.0315 0.0628
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0028 0.0012 0.0009
Brugia malayi hypothetical protein 0.0221 0.0694 0.1389
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0028 0.0012 0.0009
Schistosoma mansoni metabotropic glutamate receptor 0.0066 0.0147 0.0144
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Echinococcus multilocularis somatostatin receptor 0.0092 0.024 0.0237
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0043 0.0067 0.031
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0195 0.0603 0.06
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0036 0.0135
Brugia malayi MH2 domain containing protein 0.0028 0.0013 0.0021
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0028 0.0013 0.001
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.033 0.1081 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0052 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) Smad1 0.0028 0.0013 0.0021
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0053 0.0101 0.0098
Echinococcus granulosus neuropeptide FF receptor 2 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Leishmania major mitochondrial DNA polymerase beta 0.0712 0.2432 1
Schistosoma mansoni cpg binding protein 0.0213 0.0668 0.0665
Trichomonas vaginalis abcb9, putative 0.0055 0.0108 0.0394
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.033 0.1081 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0129 0.037 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Schistosoma mansoni hypothetical protein 0.2272 0.7952 0.7951
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0034 0.0034 0.0031
Toxoplasma gondii cytochrome p450 superfamily protein 0.0049 0.0087 0.067
Brugia malayi GnHR receptor homolog 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0038 0.0049 0.0189
Loa Loa (eye worm) cytochrome P450 family protein 0.0197 0.061 0.1221
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0013 0.0021
Entamoeba histolytica P-glycoprotein-1 0.0055 0.0108 0.3133
Loa Loa (eye worm) melatonin receptor type 1A 0.0092 0.024 0.0477
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0031 0.0023 0.0191
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0037 0.0043 0.0166
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0091 0.0234 0.0231
Echinococcus multilocularis geminin 0.2272 0.7952 0.7951
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0092 0.024 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0049 0.0087 0.0347
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0037 0.0043 0.0166
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0028 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0453 0.1517 0.3042
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0274 0.0882 0.1766
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi sulfakinin receptor protein 0.0092 0.024 0.0477
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0028 0.0012 0.0043
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0028 0.0012 0.0009
Brugia malayi Dopamine receptor protein 1 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0007
Schistosoma mansoni 60S ribosomal protein L21 0.0026 0.0005 0.0002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0091 0.0234 0.1164
Echinococcus multilocularis nmda type glutamate receptor 0.1576 0.5488 0.5487
Onchocerca volvulus 0.0028 0.0013 0.0035
Echinococcus granulosus GPCR family 2 0.0453 0.1517 0.1514
Echinococcus granulosus 7tm_1 domain containing protein 0.0092 0.024 0.0237
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0028 0.0012 0.0043
Schistosoma mansoni gabp alpha 0.0076 0.0184 0.0181
Onchocerca volvulus 0.0066 0.0147 0.0799
Schistosoma mansoni amine GPCR 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni chromobox protein 0.0047 0.0082 0.0079
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0028 0.0012 0.0043
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0072 0.0069
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.024 0.0237
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0092 0.024 0.0237
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0028 0.0013 0.001
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0337 0.1106 0.4539
Brugia malayi hypothetical protein 0.0028 0.0013 0.002
Toxoplasma gondii LsmAD domain-containing protein 0.0086 0.0217 0.17
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.0017 0.0107
Schistosoma mansoni jumonji domain containing protein 0.0052 0.0097 0.0094
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0035 0.0038 0.0071
Mycobacterium leprae conserved hypothetical protein 0.0091 0.0234 0.2662
Echinococcus granulosus serotonin receptor 0.0092 0.024 0.0237
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0028 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Brugia malayi Cyclic-nucleotide gated cation channel 0.0034 0.0034 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Trypanosoma cruzi PAB1-binding protein , putative 0.0086 0.0217 0.0881
Brugia malayi N-terminal motif family protein 0.0184 0.0564 0.1128
Loa Loa (eye worm) DR-78 0.0028 0.0013 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0139 0.0404 0.0401
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0044 0.0069 0.0133
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Loa Loa (eye worm) steroid hormone receptor 0.0059 0.0124 0.0243
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Onchocerca volvulus 0.0028 0.0012 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0025 0.0022
Entamoeba histolytica P-glycoprotein-2 0.0055 0.0108 0.3133
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Onchocerca volvulus 0.0092 0.024 0.1328
Onchocerca volvulus 0.0092 0.024 0.1328
Echinococcus granulosus intermediate filament protein 0.0058 0.0119 0.0116
Brugia malayi MAP kinase sur-1 0.0038 0.0049 0.0092
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0037 0.0043 0.0134
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0059 0.0124 0.0121
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0034 0.0031
Echinococcus granulosus zinc finger protein 0.0028 0.0011 0.0008
Onchocerca volvulus Glucosylceramidase homolog 0.0523 0.1766 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0038 0.005 0.0047
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0035 0.0038 0.028
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0712 0.2432 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0092 0.024 0.0237
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.009 0.0231 0.0228
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0015 0.0012
Schistosoma mansoni opsin-like receptor 0.0092 0.024 0.0237
Trypanosoma cruzi cytochrome P450, putative 0.0076 0.0182 0.0735
Schistosoma mansoni growth hormone secretagogue receptor 0.0092 0.024 0.0237
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.1018
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0195 0.0603 0.06
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0042 0.0039
Schistosoma mansoni alpha-glucosidase 0.0098 0.026 0.0257
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0091 0.0236 0.6855
Trichomonas vaginalis D-aminoacylase, putative 0.0091 0.0234 0.0856
Echinococcus multilocularis musashi 0.0058 0.0119 0.0116
Schistosoma mansoni biogenic amine receptor 0.0092 0.024 0.0237
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0064 0.0141 0.0138
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0066 0.0148 0.115
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0031 0.0025 0.0022
Entamoeba histolytica P-glycoprotein-2, putative 0.0055 0.0108 0.3133
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0003 0.0011
Entamoeba histolytica P-glycoprotein 5, putative 0.0055 0.0108 0.3133
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0147 0.0434 0.0431
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0102 0.0372
Toxoplasma gondii exonuclease III APE 0.012 0.0337 0.2655
Brugia malayi Tachykinin-like peptides receptor 99D 0.0092 0.024 0.0477
Onchocerca volvulus 0.0028 0.0012 0.0028
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0038 0.005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0072 0.0069
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0712 0.2432 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0038 0.0049 0.0189
Echinococcus granulosus g protein coupled receptor 0.0092 0.024 0.0237
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0059 0.0124 0.0243
Echinococcus multilocularis mitogen activated protein kinase 0.0038 0.0049 0.0046
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0013 0.001
Brugia malayi Bromodomain containing protein 0.0073 0.0173 0.0341
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0029 0.0017 0.0056
Echinococcus granulosus importin subunit beta 1 0.0048 0.0083 0.008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1432 0.4979 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0049 0.0087 0.0413
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.024 0.0237
Echinococcus multilocularis glutamate receptor 2 0.0195 0.0603 0.06
Schistosoma mansoni multidrug resistance protein 0.0055 0.0108 0.0105
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus tyrosine kinase 0.0066 0.0147 0.0144
Brugia malayi metabotropic glutamate receptor type 2 0.0066 0.0147 0.029
Loa Loa (eye worm) hypothetical protein 0.0979 0.3377 0.6779
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0053 0.0101 0.0403
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0042 0.0039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0059 0.0124 0.0121
Brugia malayi Guanylyl cyclase protein 23 0.0066 0.0147 0.029
Trypanosoma brucei hypothetical protein, conserved 0.0091 0.0234 0.0952
Echinococcus multilocularis nuclear receptor nhr 48 0.0028 0.0013 0.001
Onchocerca volvulus 0.0058 0.0119 0.0637
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0028 0.0012 0.0009
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0187 0.0577 0.292
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0092 0.024 0.0477
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0049 0.0087 0.0654
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0106 0.0287 0.1437
Onchocerca volvulus 0.0028 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0241 0.0766 0.3888
Brugia malayi beta-lactamase family protein 0.0091 0.0234 0.0464
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Schistosoma mansoni peptidase Clp (S14 family) 0.0066 0.0148 0.0145
Echinococcus multilocularis muscleblind protein 1 0.0229 0.0725 0.0722
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.0184 0.0181
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi MH2 domain containing protein 0.0028 0.0013 0.0021
Brugia malayi Receptor family ligand binding region containing protein 0.0066 0.0147 0.029
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0049 0.0087 0.0654
Brugia malayi conserved hypotetical protein 0.0028 0.0013 0.002
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0108 0.0394
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0044
Brugia malayi multidrug resistance protein 3 0.0055 0.0108 0.0211
Mycobacterium ulcerans esterase/lipase LipP 0.0091 0.0234 0.1844
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0036 0.0042 0.031
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0036 0.0042 0.0286
Schistosoma mansoni hypothetical protein 0.2272 0.7952 0.7951
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0028 0.0013 0.001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0013 0.001
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0028 0.0012 0.0009
Plasmodium vivax glutathione reductase, putative 0.0106 0.0287 0.652
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0074 0.0272
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0062 0.0133 0.013
Entamoeba histolytica hypothetical protein 0.0039 0.0051 0.1432
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0059 0.0124 0.0243
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0049 0.0087 0.0654
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0028 0.0013 0.002
Schistosoma mansoni cytochrome P450 0.0049 0.0087 0.0084
Brugia malayi nuclear hormone receptor 0.0059 0.0124 0.0243
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0091 0.0234 0.1844
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0365 0.0362
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0365 0.0362
Echinococcus multilocularis lamin dm0 0.0058 0.0119 0.0116
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0053 0.0102 0.0372
Onchocerca volvulus 0.0091 0.0234 0.1293
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Brugia malayi ABC transporter transmembrane region family protein 0.0029 0.0017 0.0027
Brugia malayi steroid hormone receptor 0.0059 0.0124 0.0243
Onchocerca volvulus 0.0092 0.024 0.1328
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0059 0.0124 0.0121
Schistosoma mansoni RAR-like nuclear receptor 0.0059 0.0124 0.0121
Schistosoma mansoni hypothetical protein 0.0092 0.024 0.0237
Entamoeba histolytica hypothetical protein 0.0036 0.0042 0.1167
Echinococcus multilocularis g-protein coupled receptor 0.0092 0.024 0.0237
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0195 0.0603 0.06
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0049 0.0087 0.0654
Leishmania major cytochrome p450-like protein 0.0049 0.0087 0.0347
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0045 0.0042
Echinococcus granulosus multidrug resistance associated protein 7 0.0029 0.0017 0.0014
Echinococcus granulosus thioredoxin glutathione reductase 0.0107 0.0291 0.0288
Brugia malayi nuclear receptor NHR-67 0.0028 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0109 0.0299 0.0594
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0119 0.0233
Loa Loa (eye worm) isocitrate dehydrogenase 0.0143 0.042 0.0839
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0102 0.0372
Entamoeba histolytica hypothetical protein 0.0064 0.0141 0.4124
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.012 0.0337 0.1693
Toxoplasma gondii thioredoxin reductase 0.0106 0.0287 0.2259
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0029 0.0017 0.0056
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0645 0.2195 0.4405
Onchocerca volvulus 0.0091 0.0234 0.1293
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0129 0.0369 0.0366
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0049 0.0087 0.0413
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0092 0.024 0.1328
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.024 0.0237
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.002 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0128 0.0366 0.0363
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Mycobacterium tuberculosis Probable lipase LipD 0.0091 0.0234 0.1164
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.1865 0.6818
Brugia malayi beta-lactamase family protein 0.0091 0.0234 0.0464
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0028 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0184 0.0564 0.1128
Onchocerca volvulus 0.0144 0.0423 0.2366
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0053 0.0101 0.0403
Loa Loa (eye worm) heterochromatin protein 1 0.0047 0.0082 0.0158
Schistosoma mansoni lamin 0.0058 0.0119 0.0116
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0241 0.0766 0.3888
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0049 0.0087 0.0654
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0007 0.0111
Echinococcus granulosus neuropeptide receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.024 0.0477
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0025 0.0003 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0187 0.0577 0.4558
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0062 0.0133 0.013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.002 0.0017
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0037 0.0043 0.0187
Entamoeba histolytica ATP-binding cassette protein, putative 0.0029 0.0017 0.0404
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.012 0.0337 0.1377
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0059 0.0124 0.0121
Mycobacterium tuberculosis Conserved protein 0.0091 0.0234 0.1164
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0059 0.0124 0.0243
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Loa Loa (eye worm) hypothetical protein 0.0032 0.0026 0.0046
Plasmodium vivax multidrug resistance protein 1, putative 0.0055 0.0108 0.1819
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus atrial natriuretic peptide receptor 0.0066 0.0147 0.0144
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0055 0.0108 0.0394
Brugia malayi hypothetical protein 0.0031 0.0025 0.0044
Schistosoma mansoni chromobox protein 0.0047 0.0082 0.0079
Toxoplasma gondii isocitrate dehydrogenase 0.0143 0.042 0.3315
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.024 0.0237
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0055 0.0108 0.0394
Brugia malayi Thioredoxin reductase 0.0106 0.0287 0.0572
Schistosoma mansoni histamine h1 receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) histone methyltransferase 0.0062 0.0133 0.0261
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0034 0.0036 0.098
Plasmodium falciparum ataxin-2 like protein, putative 0.0086 0.0217 0.5128
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0049 0.0087 0.0654
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.024 0.0237
Echinococcus granulosus peptide allatostatin:somatostatin 0.0092 0.024 0.0237
Onchocerca volvulus 0.0092 0.024 0.1328
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0035 0.0038 0.0071
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0036 0.0135
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0124 0.0121
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0091 0.0236 0.0958
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0049 0.0179
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0091 0.0236 0.0862
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0124 0.0121
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0037 0.0043 0.0251
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0028 0.0012 0.0009
Loa Loa (eye worm) G protein alpha subunit 3 0.0028 0.0012 0.0017
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0038 0.0049 0.0189
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.024 0.0237
Brugia malayi hypothetical protein 0.0066 0.0147 0.029
Schistosoma mansoni nuclear receptor 0.0028 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0027
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0037 0.0043 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0234 0.0952
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0029 0.0017 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0028 0.0012 0.0009
Trichomonas vaginalis abcb9, putative 0.0055 0.0108 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.0124 0.0243
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0028 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trichomonas vaginalis ran, putative 0.0035 0.0038 0.014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0091 0.0236 0.0233
Echinococcus granulosus g protein coupled receptor 0.0092 0.024 0.0237
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0643 0.219 0.2188
Loa Loa (eye worm) hypothetical protein 0.0091 0.0234 0.0464
Echinococcus granulosus g protein coupled receptor 0.0092 0.024 0.0237
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0052 0.0096 0.0093
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0049 0.0087 0.0347
Echinococcus granulosus metabotropic glutamate receptor 2 0.0066 0.0147 0.0144
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0036 0.0042 0.0207
Echinococcus granulosus nmda type glutamate receptor 0.1183 0.4099 0.4097
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0049 0.0087 0.0413
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0043 0.0067 0.031
Trypanosoma cruzi multidrug resistance protein E, putative 0.0029 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0143 0.042 0.1719
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0022
Brugia malayi ecdysteroid receptor 0.0059 0.0124 0.0243
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0049 0.0087 0.0347
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0091 0.0236 0.0958
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0003 0.0011
Leishmania major cytochrome p450-like protein 0.0076 0.0182 0.0735
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0453 0.1517 0.1514
Brugia malayi Latrophilin receptor protein 2 0.0453 0.1517 0.3042
Brugia malayi Fli-1 protein 0.0231 0.0733 0.1466
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0049 0.0087 0.0654
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni GTP-binding protein alpha subunit 0.0028 0.0012 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0182 0.0359
Plasmodium vivax thioredoxin reductase, putative 0.0106 0.0287 0.652
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0108 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.2736 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0108 0.0394
Plasmodium vivax ataxin-2 like protein, putative 0.0086 0.0217 0.4679
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0102 0.0372
Echinococcus granulosus tm gpcr rhodopsin 0.0761 0.2607 0.2605
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.2736 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0028 0.0013 0.002
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0049 0.0087 0.0413
Brugia malayi CXXC zinc finger family protein 0.02 0.0622 0.1244
Brugia malayi RNA binding protein 0.0128 0.0365 0.0728
Brugia malayi PHD-finger family protein 0.0032 0.0027 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.005 0.009 0.0087
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trypanosoma brucei importin beta-1 subunit, putative 0.0048 0.0083 0.0329
Loa Loa (eye worm) beta-lactamase 0.0091 0.0234 0.0464
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0365 0.0728
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0059 0.0124 0.0243
Leishmania major hypothetical protein, conserved 0.0091 0.0234 0.0952
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0092 0.024 0.0237
Echinococcus multilocularis neuropeptide FF receptor 2 0.0092 0.024 0.0237
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0195 0.0603 0.06
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0066 0.0148 0.2868
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0091 0.0236 0.0958
Loa Loa (eye worm) RNA binding protein 0.0128 0.0365 0.0728
Entamoeba histolytica hypothetical protein 0.0064 0.0141 0.4124
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0092 0.024 0.0477
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0108 0.0394
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0108 0.0105
Schistosoma mansoni glutamate receptor kainate 0.0129 0.0369 0.0366
Mycobacterium tuberculosis Conserved protein 0.0091 0.0234 0.1164
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0028 0.0012 0.0017
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0187 0.0577 0.0574
Brugia malayi G-protein coupled receptor 0.0092 0.024 0.0477
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0798 0.2736 0.5492
Trichomonas vaginalis ap endonuclease, putative 0.012 0.0337 0.1233
Echinococcus multilocularis voltage gated potassium channel 0.0045 0.0072 0.0069
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0147 0.0434 0.0431
Onchocerca volvulus 0.0092 0.024 0.1328
Schistosoma mansoni glutamate receptor kainate 0.0129 0.0369 0.0366
Echinococcus granulosus microtubule associated protein 2 0.0575 0.1946 0.1944
Trichomonas vaginalis maltase-glucoamylase, putative 0.0025 0.0003 0.0011
Schistosoma mansoni survival motor neuron protein 0.0045 0.0073 0.007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.012 0.0337 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0035 0.0038 0.0745
Mycobacterium ulcerans hypothetical protein 0.0091 0.0234 0.1844
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0037 0.0043 0.0966
Brugia malayi glutathione reductase 0.0106 0.0287 0.0572
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0045 0.0072 0.0139
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0028 0.0012 0.0017
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0034 0.0125
Echinococcus granulosus ubiquitin specific protease 41 0.0091 0.0236 0.0233
Echinococcus multilocularis isocitrate dehydrogenase 0.0143 0.042 0.0418
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0036 0.0042 0.031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.0577 0.4624
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0108 0.0105
Schistosoma mansoni microtubule-associated protein tau 0.0575 0.1946 0.1944
Echinococcus multilocularis mothers against decapentaplegic 5 0.0028 0.0013 0.001
Chlamydia trachomatis glutamine binding protein 0.033 0.1081 1
Schistosoma mansoni hypothetical protein 0.0092 0.024 0.0237
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0028 0.0012 0.0017
Loa Loa (eye worm) glutamate receptor 2 0.0129 0.0369 0.0736
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.033 0.1081 0.5501
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.01 0.0268 0.1091
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi larval opioid receptor 0.0092 0.024 0.0477
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.1865 0.6818
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0241 0.0766 0.8887
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0028 0.0012 0.0009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0091 0.0236 0.0233
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0365 0.0362
Echinococcus granulosus jumonji domain containing protein 0.0028 0.0012 0.0009
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0029 0.0017 0.0056
Echinococcus multilocularis glutamate receptor 2 0.0066 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0007
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0052 0.0096 0.0383
Echinococcus granulosus smad 0.0028 0.0013 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus neuropeptide receptor 0.0092 0.024 0.0237
Schistosoma mansoni coup transcription factor 0.0059 0.0124 0.0121
Echinococcus multilocularis g protein coupled receptor 0.0092 0.024 0.0237
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0034 0.0036 0.0236
Schistosoma mansoni hypothetical protein 0.0453 0.1517 0.1514
Brugia malayi Serotonin receptor 0.0092 0.024 0.0477
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0035 0.0038 0.0844
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0108 0.0394
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0028 0.0012 0.0009
Brugia malayi RE15519p 0.0092 0.024 0.0477
Schistosoma mansoni tyrosine kinase 0.0066 0.0147 0.0144
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0036 0.0042 0.0181
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0054 0.0105 0.0102
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.024 0.0237
Brugia malayi multidrug resistance related protein 1 0.0029 0.0017 0.0027
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0066 0.0147 0.0144
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.024 0.0237
Schistosoma mansoni biogenic amine receptor 0.0092 0.024 0.0237
Schistosoma mansoni zinc finger protein 0.0028 0.0013 0.001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0453 0.1517 0.1514
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0049 0.0087 0.0654
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0091 0.0234 0.1164
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0049 0.0087 0.0654
Plasmodium falciparum thioredoxin reductase 0.0106 0.0287 0.6814
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0144 0.0141
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.2736 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0147 0.029
Mycobacterium tuberculosis Probable esterase LipL 0.0091 0.0234 0.1164
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0063
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.024 0.0237
Entamoeba histolytica hypothetical protein 0.0029 0.0017 0.0404
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0024 0.0041
Schistosoma mansoni opsin-like receptor 0.0092 0.024 0.0237
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0108 0.0105
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.012 0.0337 0.0335
Trypanosoma brucei trypanothione reductase 0.0106 0.0287 0.1171
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0073 0.0141
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0028 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0013 0.0021
Loa Loa (eye worm) cytochrome P450 0.0049 0.0087 0.017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.016
Echinococcus multilocularis tyrosine kinase 0.0066 0.0147 0.0144
Schistosoma mansoni hypothetical protein 0.0453 0.1517 0.1514
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0143 0.042 0.1719
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0092 0.024 0.0477
Brugia malayi tailless protein 0.0028 0.0013 0.002
Entamoeba histolytica Ran family GTPase 0.0035 0.0038 0.1053
Loa Loa (eye worm) hypothetical protein 0.0086 0.0217 0.043
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0147 0.029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0012
Echinococcus granulosus glutamate NMDA receptor subunit 0.0129 0.0369 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0028 0.0012 0.0009
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0053 0.0101 0.0403
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni neuropeptide receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0229 0.0725 0.1451
Brugia malayi Muscleblind-like protein 0.0229 0.0725 0.1451
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.3715
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0643 0.219 0.2188
Loa Loa (eye worm) hypothetical protein 0.0274 0.0882 0.1766
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0007 0.0015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0059 0.0124 0.0121
Entamoeba histolytica exodeoxyribonuclease III, putative 0.012 0.0337 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.024 0.0237
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0037 0.0043 0.0166
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Loa Loa (eye worm) hypothetical protein 0.0129 0.037 0.0736
Schistosoma mansoni hypothetical protein 0.0453 0.1517 0.1514
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.01 0.0268 0.1091
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0059 0.0124 0.0121
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0059 0.0124 0.0121
Trichomonas vaginalis penicillin-binding protein, putative 0.0091 0.0234 0.0856
Onchocerca volvulus 0.0045 0.0073 0.0377
Brugia malayi Melatonin receptor type 1A 0.0092 0.024 0.0477
Brugia malayi intermediate filament protein 0.0058 0.0119 0.0233
Schistosoma mansoni amine GPCR 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0008 0.0029
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0028 0.0012 0.0009
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.051 0.1718 0.3445
Treponema pallidum exodeoxyribonuclease (exoA) 0.012 0.0337 0.2843
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0643 0.219 0.2188
Onchocerca volvulus Protein ultraspiracle homolog 0.0059 0.0124 0.0665
Loa Loa (eye worm) latrophilin receptor protein 2 0.0453 0.1517 0.3042
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0034 0.0031
Echinococcus multilocularis jumonji domain containing protein 0.0028 0.0012 0.0009
Leishmania major importin beta-1 subunit, putative 0.0039 0.0051 0.0197
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0425 0.1416 0.1413
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0268 0.0861 0.4374
Onchocerca volvulus 0.0092 0.024 0.1328
Onchocerca volvulus 0.0092 0.024 0.1328
Schistosoma mansoni neuropeptide receptor 0.0092 0.024 0.0237
Entamoeba histolytica ATP-binding cassette protein, putative 0.0029 0.0017 0.0404
Mycobacterium tuberculosis Probable lipase LipE 0.0091 0.0234 0.1164
Loa Loa (eye worm) hypothetical protein 0.0047 0.0079 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Schistosoma mansoni smdr2 0.0055 0.0108 0.0105
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0241 0.0766 0.3888
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0037 0.0043 0.0297
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trypanosoma cruzi extracellular receptor, putative 0.0066 0.0147 0.0594
Echinococcus multilocularis ubiquitin specific protease 41 0.0091 0.0236 0.0233
Echinococcus granulosus arachidonate 5 lipoxygenase 0.009 0.0231 0.0228
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0036 0.0135
Loa Loa (eye worm) multidrug resistance protein 3 0.0055 0.0108 0.0211
Loa Loa (eye worm) CXXC zinc finger family protein 0.02 0.0622 0.1244
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0072 0.0069
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0013 0.001
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.1018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0044
Leishmania major p-glycoprotein 0.0055 0.0108 0.0431
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0038 0.0049 0.0364
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0195 0.0603 0.06
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0066 0.0147 0.029
Brugia malayi hypothetical protein 0.0064 0.0141 0.0277
Entamoeba histolytica hypothetical protein 0.0025 0.0003 0.0000022899
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0028 0.0012 0.0017
Mycobacterium leprae Probable lipase LipE 0.0091 0.0234 0.2662
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.001
Onchocerca volvulus 0.0092 0.024 0.1328
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0034 0.0031
Schistosoma mansoni nuclear receptor nhr-48 0.0028 0.0013 0.001
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0043 0.0166
Echinococcus granulosus neuropeptide s receptor 0.153 0.5325 0.5324
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.2736 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0114 0.0315 0.0628
Giardia lamblia Kinase, CMGC MAPK 0.0038 0.0049 0.1073
Leishmania major GTP-binding protein, putative 0.0035 0.0038 0.0145
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0108 0.0394
Echinococcus granulosus chromobox protein 1 0.0047 0.0082 0.0079
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0147 0.029
Loa Loa (eye worm) hypothetical protein 0.0058 0.012 0.0235
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0037 0.0043 0.0166
Echinococcus multilocularis beta LACTamase domain containing family member 0.0091 0.0234 0.0231
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0066 0.0148 0.115
Loa Loa (eye worm) RGC/RGC protein kinase 0.0066 0.0147 0.029
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0028 0.0012 0.0017
Onchocerca volvulus 0.02 0.0622 0.3499
Mycobacterium tuberculosis Conserved protein 0.0091 0.0234 0.1164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Echinococcus multilocularis microtubule associated protein 2 0.0575 0.1946 0.1944
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0036 0.0042 0.0286
Trichomonas vaginalis mercuric reductase, putative 0.0037 0.0043 0.0158
Mycobacterium ulcerans lipase LipD 0.0091 0.0234 0.1844
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0102 0.0372
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0195 0.0603 0.06
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.024 0.0477
Echinococcus granulosus 7TM GPCR rhodopsin 0.0092 0.024 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0049 0.0087 0.0654
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0053 0.0101 0.0197
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0108 0.0394
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0059 0.0124 0.0121
Loa Loa (eye worm) fli-1 protein 0.0231 0.0733 0.1466
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0008 0.0029
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0028 0.0012 0.0009
Trichomonas vaginalis abcb9, putative 0.0055 0.0108 0.0394
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0034 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0059 0.0124 0.0243
Echinococcus granulosus sex peptide receptor 0.0092 0.024 0.0237
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0091 0.0234 0.0464
Brugia malayi Glutamate receptor 1 precursor 0.0129 0.0369 0.0736
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus glutamate receptor 2 0.0066 0.0147 0.0144
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Entamoeba histolytica P-glyco protein 6, putative 0.0055 0.0108 0.3133
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0024 0.0041
Entamoeba histolytica P-glycoprotein-2 0.0055 0.0108 0.3133
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0028 0.0012 0.0017
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0037 0.0043 0.0166
Echinococcus multilocularis dro:myosuppressin receptor 0.0092 0.024 0.0237
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0129 0.037 0.0367
Trichomonas vaginalis importin beta-1, putative 0.0039 0.0051 0.0186
Echinococcus multilocularis lysosomal alpha glucosidase 0.0114 0.0315 0.0313
Trypanosoma brucei cytochrome P450, putative 0.0076 0.0182 0.0735
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi Glutamate receptor 2 precursor 0.0129 0.0369 0.0736
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0015 0.0055
Brugia malayi hypothetical protein 0.0031 0.0025 0.0044
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0053 0.0101 0.0098
Echinococcus multilocularis fmrfamide receptor 0.0092 0.024 0.0237
Schistosoma mansoni amine GPCR 0.0092 0.024 0.0237
Echinococcus granulosus glutamate receptor 2 0.0195 0.0603 0.06
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.1766 0.6453
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0059 0.0124 0.0121
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.1018
Plasmodium falciparum multidrug resistance protein 1 0.0055 0.0108 0.251
Brugia malayi nuclear receptor NHR-88 0.0059 0.0124 0.0243
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0108 0.0394
Schistosoma mansoni cpg binding protein 0.0213 0.0668 0.0665
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0037 0.0043 0.0966
Treponema pallidum NADH oxidase 0.0037 0.0043 0.0013
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0143 0.042 0.1719
Trichomonas vaginalis glutathione reductase, putative 0.0037 0.0043 0.0158
Brugia malayi ORL1-like opioid receptor 0.0092 0.024 0.0477
Brugia malayi G-protein coupled receptor 0.0092 0.024 0.0477
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi G-protein alpha subunit 0.0028 0.0012 0.0017
Onchocerca volvulus 0.0059 0.0124 0.0665
Echinococcus multilocularis g protein coupled receptor 0.0092 0.024 0.0237
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0025 0.0044
Loa Loa (eye worm) CYP4Cod1 0.0076 0.0182 0.0359
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Schistosoma mansoni ran 0.0035 0.0038 0.0035
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0092 0.024 0.0477
Entamoeba histolytica ATP-binding cassette protein, putative 0.0029 0.0017 0.0404
Leishmania major hypothetical protein, conserved 0.0086 0.0217 0.0881
Schistosoma mansoni amine GPCR 0.0092 0.024 0.0237
Leishmania major pantothenate kinase subunit, putative 0.0025 0.0003 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0039 0.0051 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.0124 0.0243
Trypanosoma cruzi trypanothione reductase, putative 0.0106 0.0287 0.1171
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0144 0.0141
Giardia lamblia ABC transporter, putative 0.0029 0.0017 0.0073
Echinococcus granulosus FTZ F1 alpha 0.0059 0.0124 0.0121
Echinococcus multilocularis chromobox protein 1 0.0047 0.0082 0.0079
Brugia malayi photoreceptor-specific nuclear receptor 0.0059 0.0124 0.0243
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0365 0.0728
Mycobacterium ulcerans beta-lactamase 0.0091 0.0234 0.1844
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0059
Schistosoma mansoni metabotropic glutamate receptor 0.0066 0.0147 0.0144
Onchocerca volvulus 0.0091 0.0234 0.1293
Brugia malayi Dopamine receptor protein 2 0.0092 0.024 0.0477
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Echinococcus multilocularis expressed protein 0.0028 0.0012 0.0009
Schistosoma mansoni tyrosine kinase 0.0066 0.0147 0.0144
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0045 0.0042
Schistosoma mansoni ets-related 0.0231 0.0733 0.073
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0578 0.196 1
Brugia malayi putative neuropeptide receptor NPR1 0.0092 0.024 0.0477
Schistosoma mansoni glutamate receptor AMPA 0.0129 0.0369 0.0366
Schistosoma mansoni Smad4 0.0028 0.0013 0.001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0128 0.0125
Schistosoma mansoni alpha-glucosidase 0.0098 0.026 0.0257
Plasmodium falciparum glutathione reductase 0.0106 0.0287 0.6814
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0022 0.0019
Echinococcus multilocularis thioredoxin glutathione reductase 0.0107 0.0291 0.0288
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0092 0.024 0.0477
Echinococcus granulosus peptidase Clp S14 family 0.0043 0.0067 0.0064
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.003 0.0019 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.024 0.0237
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.012 0.0337 0.1377
Echinococcus granulosus g-protein coupled receptor 0.0092 0.024 0.0237
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0052 0.0096 0.0725
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0066 0.0148 0.1144
Echinococcus granulosus hypothetical protein 0.0092 0.024 0.0237
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0049 0.0087 0.0654
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0129 0.0369 0.0366
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0092 0.024 0.0477
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0049 0.0087 0.0413
Echinococcus multilocularis mitogen activated protein kinase 3 0.0038 0.0049 0.0046
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0013 0.0035
Schistosoma mansoni hypothetical protein 0.0038 0.005 0.0047
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0034 0.0034 0.0031
Schistosoma mansoni alpha-1 adrenergic receptor 0.0092 0.024 0.0237
Echinococcus multilocularis neuropeptide s receptor 0.153 0.5325 0.5324
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.012 0.0337 0.2681
Toxoplasma gondii isocitrate dehydrogenase 0.0143 0.042 0.3315
Loa Loa (eye worm) transcription factor SMAD2 0.0413 0.1373 0.2754
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0055 0.0108 0.0211
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0028 0.0012 0.0017
Brugia malayi hypothetical protein 0.0028 0.0013 0.002
Onchocerca volvulus 0.0092 0.024 0.1328
Echinococcus granulosus cpg binding protein 0.0213 0.0668 0.0665
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0076 0.0182 0.1418
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0091 0.0236 0.0233
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0091 0.0236 0.0468
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0013 0.001
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0013 0.002
Echinococcus multilocularis multidrug resistance protein 1 0.0036 0.0042 0.0039
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0038 0.0049 0.0189
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0066 0.0148 0.1652
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Echinococcus multilocularis multidrug resistance protein 1 0.0055 0.0108 0.0105
Leishmania major trypanothione reductase 0.0106 0.0287 0.1171
Schistosoma mansoni lamin 0.0058 0.0119 0.0116
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0091 0.0236 0.0233
Brugia malayi Cytochrome P450 family protein 0.0076 0.0182 0.0359
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0049 0.0087 0.0413
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0034 0.0031
Onchocerca volvulus 0.0066 0.0146 0.0793
Toxoplasma gondii histone lysine methyltransferase SET1 0.0381 0.1262 1
Brugia malayi Receptor family ligand binding region containing protein 0.0066 0.0147 0.029
Schistosoma mansoni hypothetical protein 0.0147 0.0434 0.0431
Loa Loa (eye worm) hypothetical protein 0.0092 0.024 0.0477
Brugia malayi chromobox protein homolog 3 0.0027 0.0008 0.001
Onchocerca volvulus 0.0092 0.024 0.1328
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0129 0.0369 0.0366
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0059 0.0124 0.0243
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0039 0.0051 0.0186
Onchocerca volvulus 0.0066 0.0147 0.0799
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0059 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0229 0.0725 0.1451
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0122 0.0345 0.141
Loa Loa (eye worm) hypothetical protein 0.0059 0.0124 0.0243
Echinococcus multilocularis sex peptide receptor 0.0092 0.024 0.0237
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0034 0.0031
Echinococcus multilocularis survival motor neuron protein 1 0.0221 0.0694 0.0691
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.002
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0053 0.0101 0.2925
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0028 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0091 0.0234 0.0464
Echinococcus granulosus dro:myosuppressin receptor 0.0092 0.024 0.0237
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0035 0.0038 0.0145
Loa Loa (eye worm) hypothetical protein 0.0091 0.0234 0.0464
Onchocerca volvulus 0.0028 0.0012 0.0028
Mycobacterium tuberculosis Probable reductase 0.0241 0.0766 0.3888
Trichomonas vaginalis helicase, putative 0.0045 0.0074 0.0272
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0268 0.0861 0.4374
Loa Loa (eye worm) thioredoxin reductase 0.0106 0.0287 0.0572
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0052 0.0096 0.0458
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0037 0.0043 0.0134
Schistosoma mansoni hypothetical protein 0.051 0.1718 0.1715
Echinococcus multilocularis allatostatin A receptor 0.0092 0.024 0.0237
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0035 0.0038 0.0145
Schistosoma mansoni ap endonuclease 0.012 0.0337 0.0335
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.024 0.0237
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0037 0.0043 0.0166
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.012 0.0337 0.8012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0049 0.0087 0.0413
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0034 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.024 0.0237
Echinococcus multilocularis 0.0049 0.0087 0.0084
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0013 0.0035
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0453 0.1517 0.3042
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0066 0.0147 0.0144
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0034 0.0036 0.026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.012 0.0337 0.1377
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0015 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0113 0.011
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0092 0.024 0.0237
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0143 0.042 0.0418
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0055 0.0108 0.0832
Loa Loa (eye worm) glutamate receptor 0.0066 0.0147 0.029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0064 0.0141 0.0138
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0053 0.0101 0.0197
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0031 0.0025 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0643 0.219 0.2188
Echinococcus granulosus inositol monophosphatase 1 0.0034 0.0036 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0007 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0268 0.0861 0.4374
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.003 0.0019 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.024 0.0237
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0143 0.042 1
Echinococcus granulosus mitogen activated protein kinase 0.0038 0.0049 0.0046
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0028 0.0012 0.0009
Onchocerca volvulus 0.0092 0.024 0.1328
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.024 0.0477
Echinococcus granulosus geminin 0.2272 0.7952 0.7951
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.0124 0.0243
Schistosoma mansoni smad1 5 8 and 0.0028 0.0013 0.001
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0092 0.024 0.0237
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0055 0.0108 0.0832
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0129 0.0369 0.0366
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.0124 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0259 0.0829 0.3029
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0049 0.0179
Echinococcus granulosus glutamate receptor NMDA 0.1117 0.3866 0.3864
Brugia malayi ABC transporter family protein 0.0055 0.0108 0.0211
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0184 0.0564 0.3169
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0007 0.0111
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0091 0.0236 0.696
Loa Loa (eye worm) hypothetical protein 0.0091 0.0234 0.0464
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0031 0.0025 0.0022
Echinococcus granulosus metabotropic glutamate receptor 5 0.0066 0.0147 0.0144
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0108 0.0105
Brugia malayi exodeoxyribonuclease III family protein 0.012 0.0337 0.0672
Schistosoma mansoni voltage-gated potassium channel 0.0139 0.0404 0.0401
Brugia malayi hypothetical protein 0.0092 0.024 0.0477
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0037 0.0043 0.0166
Onchocerca volvulus 0.0092 0.024 0.1328
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0028 0.0012 0.0009
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0143 0.042 0.2118

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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