Detailed information for compound 657456

Basic information

Technical information
  • TDR Targets ID: 657456
  • Name: 3-[(4-tert-butylphenyl)sulfonylamino]-3-pheny lpropanoic acid
  • MW: 361.455 | Formula: C19H23NO4S
  • H donors: 2 H acceptors: 4 LogP: 3.59 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CC(c1ccccc1)NS(=O)(=O)c1ccc(cc1)C(C)(C)C
  • InChi: 1S/C19H23NO4S/c1-19(2,3)15-9-11-16(12-10-15)25(23,24)20-17(13-18(21)22)14-7-5-4-6-8-14/h4-12,17,20H,13H2,1-3H3,(H,21,22)
  • InChiKey: WPRMTFRRWGVAEV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[(4-tert-butylphenyl)sulfonylamino]-3-phenyl-propanoic acid
  • 3-[(4-tert-butylphenyl)sulfonylamino]-3-phenyl-propionic acid
  • EU-0074297

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Brugia malayi nuclear hormone receptor 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Probable esterase LipL 0.0062 0.0123 0.0877
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Onchocerca volvulus 0.0845 0.2549 1
Echinococcus multilocularis chromobox protein 1 0.0073 0.0159 0.0157
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0014
Schistosoma mansoni cpg binding protein 0.0107 0.0264 0.0263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0232 0.0651 0.2542
Plasmodium falciparum glutathione reductase 0.0027 0.0016 0.0046
Echinococcus multilocularis muscleblind protein 1 0.0243 0.0684 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0597 0.178 0.5024
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0123 0.0123
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0195 0.0536 0.0535
Echinococcus granulosus lamin dm0 0.0024 0.0006 0.0005
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0015 0.0014
Plasmodium falciparum thioredoxin reductase 0.0027 0.0016 0.0046
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0239 0.0237
Schistosoma mansoni zinc finger protein 0.0092 0.0217 0.0216
Brugia malayi beta-NAC-like protein 0.0026 0.0013 0.0012
Brugia malayi hypothetical protein 0.0092 0.0217 0.0216
Loa Loa (eye worm) inositol-1 0.0028 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Loa Loa (eye worm) hypothetical protein 0.0178 0.0482 0.0481
Echinococcus multilocularis lysosomal alpha glucosidase 0.0202 0.0556 0.0555
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0232 0.0651 0.1837
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.009 0.0089
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0046 0.0074 0.0072
Echinococcus multilocularis ubiquitin specific protease 41 0.003 0.0025 0.0024
Schistosoma mansoni RAR-like nuclear receptor 0.0195 0.0536 0.0535
Echinococcus multilocularis lamin 0.0024 0.0006 0.0005
Onchocerca volvulus 0.0621 0.1853 0.7264
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0027 0.0016 0.0044
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0481 0.1421 0.1419
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0033
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0006 0.0005
Plasmodium vivax SET domain protein, putative 0.008 0.018 0.0692
Brugia malayi chromobox protein homolog 3 0.0041 0.0059 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Onchocerca volvulus 0.008 0.0179 0.0681
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0013 0.0037
Plasmodium vivax JmjC domain containing protein 0.0024 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0063 0.0178
Onchocerca volvulus Alhambra homolog 0.0073 0.0159 0.0601
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0025 0.0009 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0022 0.0062
Echinococcus multilocularis insulin receptor 0.0355 0.1032 0.1031
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Echinococcus granulosus cpg binding protein 0.0107 0.0264 0.0263
Plasmodium falciparum serine repeat antigen 9 0.0232 0.0651 0.2542
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0845 0.2549 0.2548
Trichomonas vaginalis glutaminase, putative 0.0206 0.0569 0.1604
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.0251 0.025
Schistosoma mansoni sex comb on midleg homolog 0.008 0.0179 0.0178
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Mycobacterium ulcerans lipase LipD 0.0062 0.0123 0.0877
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0092 0.0258
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0845 0.2549 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0195 0.0536 0.0535
Brugia malayi MH1 domain containing protein 0.0027 0.0015 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Leishmania major cathepsin L-like protease 0.0957 0.2894 0.817
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0025 0.0025
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0052 0.0094 0.0093
Echinococcus multilocularis ecdysone induced protein 78C 0.0195 0.0536 0.0535
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0005 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0037 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0195 0.0536 0.0535
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0239 0.0237
Mycobacterium ulcerans beta-lactamase 0.0062 0.0123 0.0877
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Trypanosoma cruzi trypanothione reductase, putative 0.0078 0.0173 0.0173
Onchocerca volvulus 0.0597 0.178 0.6974
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0063 0.0179
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0232 0.0651 0.2542
Echinococcus multilocularis inositol monophosphatase 1 0.0028 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Echinococcus multilocularis cathepsin b 0.3252 1 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0344 0.0996 0.0996
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0651 0.1837
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0177 0.0482 0.3507
Loa Loa (eye worm) hypothetical protein 0.0073 0.0159 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0022 0.0062
Brugia malayi nuclear receptor RXR 0.0092 0.0217 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Echinococcus granulosus geminin 0.061 0.182 0.1819
Toxoplasma gondii histone lysine methyltransferase SET1 0.0192 0.0528 0.1479
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0159 0.0447
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0092 0.0217 0.0216
Entamoeba histolytica cysteine proteinase 1, putative 0.0481 0.1421 0.4948
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Brugia malayi hypothetical protein 0.0043 0.0065 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Brugia malayi hypothetical protein 0.0103 0.0251 0.025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Brugia malayi MH2 domain containing protein 0.0027 0.0015 0.0014
Schistosoma mansoni nuclear hormone receptor 0.0195 0.0536 0.0535
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0013 0.0013
Echinococcus granulosus chromobox protein 1 0.0073 0.0159 0.0157
Echinococcus granulosus dnaJ subfamily B 0.0794 0.239 0.2389
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1166 0.3542 0.3542
Trichomonas vaginalis sucrase-isomaltase, putative 0.0045 0.0071 0.0199
Mycobacterium tuberculosis Conserved protein 0.0062 0.0123 0.0877
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0005 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0393 0.1149 0.1148
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0005 0.0004
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0159 0.0438
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0463 0.1366 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0034 0.0033
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0014
Trypanosoma brucei RNA helicase, putative 0.0068 0.0143 0.0393
Echinococcus multilocularis lysine specific demethylase 5A 0.0089 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.0536 0.0535
Plasmodium falciparum glutathione reductase 0.0078 0.0173 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0025 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus multilocularis thioredoxin glutathione reductase 0.0078 0.0173 0.0172
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Echinococcus multilocularis zinc finger protein 0.0055 0.0102 0.01
Trypanosoma cruzi cysteine peptidase, putative 0.0845 0.2549 0.2549
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0018
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0948 0.2867 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Echinococcus granulosus microtubule associated protein 2 0.2248 0.6892 0.6891
Entamoeba histolytica cysteine proteinase, putative 0.0845 0.2549 0.8891
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0542 0.054
Trypanosoma cruzi cysteine peptidase, putative 0.0249 0.0702 0.0702
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0027 0.0016 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Schistosoma mansoni loxhd1 0.003 0.0026 0.0024
Brugia malayi beta-lactamase family protein 0.0062 0.0123 0.0122
Onchocerca volvulus Protein ultraspiracle homolog 0.0195 0.0536 0.2082
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0071 0.0154 0.0152
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1166 0.3542 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0845 0.2549 0.2548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis chaperonin, putative 0.0024 0.0006 0.0016
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0005 0.0004
Brugia malayi glutaminase DH11.1 0.0206 0.0569 0.0567
Plasmodium falciparum thioredoxin reductase 0.0078 0.0173 0.0664
Echinococcus granulosus transcription factor Dp 1 0.0026 0.0014 0.0013
Brugia malayi Sulfatase family protein 0.0053 0.0096 0.0095
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.008 0.0179 0.0178
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3252 1 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0281 0.028
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0027 0.0016 0.0033
Brugia malayi Muscleblind-like protein 0.0243 0.0684 0.0683
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Trypanosoma cruzi cysteine proteinase, putative 0.0481 0.1421 0.1421
Giardia lamblia Cathepsin B precursor 0.1166 0.3542 1
Brugia malayi nuclear receptor NHR-88 0.0195 0.0536 0.0535
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0053 0.0096 0.0095
Giardia lamblia NADH oxidase lateral transfer candidate 0.0027 0.0016 0.0028
Entamoeba histolytica hypothetical protein 0.0026 0.0013 0.0033
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0006 0.0005
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0187 0.0186
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0092 0.0217 0.0216
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0074 0.0197
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0123 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0092 0.009
Schistosoma mansoni cathepsin F (C01 family) 0.0845 0.2549 0.2548
Echinococcus multilocularis lipoxygenase domain containing protein 0.003 0.0026 0.0024
Echinococcus granulosus smad 0.0027 0.0015 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0542 0.054
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0597 0.178 0.1779
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0071 0.0154 0.0152
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0232 0.0651 0.2542
Echinococcus granulosus neuropeptide receptor A26 0.0917 0.2771 0.277
Trypanosoma cruzi cysteine proteinase, putative 0.0481 0.1421 0.1421
Echinococcus granulosus cathepsin l1 0.0845 0.2549 0.2548
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.009 0.0212 0.021
Giardia lamblia Hypothetical protein 0.0053 0.0096 0.0255
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0232 0.0651 0.065
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0232 0.0651 0.2542
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Echinococcus multilocularis cathepsin L cysteine protease 0.0845 0.2549 0.2548
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0005 0.0005
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0119 0.0335
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0063 0.0435
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0027 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Echinococcus granulosus peregrin 0.0079 0.0177 0.0176
Loa Loa (eye worm) hypothetical protein 0.0052 0.0094 0.0093
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Echinococcus multilocularis cathepsin L cysteine protease 0.0845 0.2549 0.2548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.003 0.0025 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Echinococcus multilocularis nuclear receptor nhr 48 0.0092 0.0217 0.0216
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0092 0.0247
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0053 0.0096 0.0354
Loa Loa (eye worm) runx1 0.0042 0.0062 0.006
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0005 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0197 0.0543 0.3957
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0086
Echinococcus granulosus SAM and MBT domain containing protein 0.008 0.0179 0.0178
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0092 0.009
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.0651 0.065
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) hypothetical protein 0.008 0.0179 0.0178
Trypanosoma cruzi ISWI complex protein 0.0038 0.0051 0.0051
Loa Loa (eye worm) cysteine protease 0.0845 0.2549 0.2548
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0028 0.0018 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0481 0.1421 0.401
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0481 0.1421 0.1419
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0232 0.0651 0.2542
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0037
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3252 1 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.0651 0.1824
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0071 0.0154 0.0152
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0005 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Plasmodium vivax multidomain scavenger receptor, putative 0.003 0.0026 0.0085
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0092 0.0217 0.0216
Brugia malayi intermediate filament protein 0.0024 0.0006 0.0005
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0006 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Trypanosoma cruzi polo-like protein kinase, putative 0.0071 0.0154 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0053 0.0096 0.0271
Echinococcus multilocularis serine protein kinase ATM 0.003 0.0025 0.0024
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0027 0.0016 0.0086
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.009 0.0088
Schistosoma mansoni nuclear hormone receptor 0.0092 0.0217 0.0216
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0092 0.0092
Toxoplasma gondii FATC domain-containing protein 0.003 0.0025 0.006
Leishmania major hypothetical protein, conserved 0.0024 0.0005 0.0015
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0091 0.0214 0.0212
Trichomonas vaginalis penicillin-binding protein, putative 0.0062 0.0123 0.0348
Plasmodium falciparum LCCL domain-containing protein 0.003 0.0026 0.0085
Brugia malayi cathepsin Z-like cysteine proteinase 0.0232 0.0651 0.065
Loa Loa (eye worm) DR-78 0.0092 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.0176 0.0478 0.0477
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0053 0.0096 0.0677
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.0651 0.065
Schistosoma mansoni thyroid hormone receptor 0.0195 0.0536 0.0535
Echinococcus multilocularis muscleblind protein 0.0243 0.0684 0.0683
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0197 0.0542 0.054
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Mycobacterium ulcerans glutaminase 0.0206 0.0569 0.4145
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0155 0.0414 0.0412
Trypanosoma brucei polo-like protein kinase 0.0071 0.0154 0.0423
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0024 0.0005 0.0004
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0154 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Mycobacterium tuberculosis Conserved protein 0.0062 0.0123 0.0877
Schistosoma mansoni ap endonuclease 0.0042 0.0063 0.0062
Echinococcus multilocularis neutral alpha glucosidase AB 0.0045 0.0071 0.007
Leishmania major basic transcription factor 3a, putative 0.0026 0.0013 0.0038
Plasmodium falciparum serine repeat antigen 7 0.0232 0.0651 0.2542
Schistosoma mansoni kinase 0.0037 0.0045 0.0044
Brugia malayi Smad1 0.0027 0.0015 0.0014
Entamoeba histolytica serine/threonine protein kinase, putative 0.0071 0.0154 0.0522
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0092 0.0217 0.0216
Trypanosoma cruzi cysteine protease, putative 0.0481 0.1421 0.1421
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0195 0.0536 0.0535
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.003 0.0025 0.0024
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0039
Schistosoma mansoni alpha glucosidase 0.0045 0.0071 0.007
Echinococcus multilocularis geminin 0.061 0.182 0.1819
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0013 0.0026
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0016 0.0016
Brugia malayi Furin-like cysteine rich region family protein 0.1112 0.3375 0.3374
Echinococcus multilocularis Smad4 0.0027 0.0015 0.0014
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0103 0.0251 0.025
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0005 0.0004
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.003 0.0025 0.0081
Giardia lamblia Fructose-bisphosphate aldolase 0.0948 0.2867 0.8089
Giardia lamblia Cathepsin L-like protease 0.0232 0.0651 0.1824
Loa Loa (eye worm) hypothetical protein 0.025 0.0705 0.0704
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Schistosoma mansoni tyrosine kinase 0.0598 0.1782 0.1781
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.0542 0.054
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0005 0.0004
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0025 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Onchocerca volvulus 0.0092 0.0217 0.0829
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Probable sulfatase 0.0053 0.0096 0.0677
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0027 0.0016 0.197
Schistosoma mansoni hypothetical protein 0.061 0.182 0.1819
Schistosoma mansoni bromodomain containing protein 0.0164 0.0441 0.044
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0355 0.1032 0.1031
Brugia malayi Glycosyl hydrolases family 31 protein 0.0202 0.0556 0.0555
Loa Loa (eye worm) MBCTL1 0.0091 0.0214 0.0212
Schistosoma mansoni lamin 0.0024 0.0006 0.0005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0558 0.1658 0.1657
Loa Loa (eye worm) hypothetical protein 0.0096 0.0231 0.0229
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Echinococcus multilocularis FTZ F1 alpha 0.0195 0.0536 0.0535
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0232 0.0651 0.2542
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3252 1 1
Brugia malayi F/Y-rich N-terminus family protein 0.0061 0.0122 0.012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0027 0.0016 0.0033
Mycobacterium tuberculosis Possible hydrolase 0.0053 0.0096 0.0677
Echinococcus granulosus neutral alpha glucosidase AB 0.0045 0.0071 0.007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0025 0.0071
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0063 0.0062
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0119 0.0842
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0091 0.0214 0.0212
Echinococcus multilocularis cysteine protease 0.0845 0.2549 0.2548
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0103 0.0251 0.025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1166 0.3542 0.3542
Onchocerca volvulus 0.0082 0.0187 0.0713
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0073 0.0159 0.0158
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0092 0.0217 0.0216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Brugia malayi Papain family cysteine protease containing protein 0.0481 0.1421 0.1419
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Schistosoma mansoni alpha-glucosidase 0.0174 0.0469 0.0468
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0063 1
Plasmodium vivax hypothetical protein, conserved 0.003 0.0025 0.0081
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0006 0.0005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0195 0.0536 0.0535
Schistosoma mansoni retinoic acid receptor RXR 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Probable hydrolase 0.0062 0.0123 0.0877
Loa Loa (eye worm) ctsf protein 0.0845 0.2549 0.2548
Onchocerca volvulus 0.0195 0.0536 0.2082
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.003 0.0025 0.0074
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0197 0.0543 0.3957
Brugia malayi Bromodomain containing protein 0.0096 0.023 0.0229
Onchocerca volvulus 0.0051 0.009 0.0329
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus multilocularis histone acetyltransferase MYST2 0.0091 0.0214 0.0212
Schistosoma mansoni zinc finger protein 0.0038 0.0051 0.005
Echinococcus multilocularis Protein lozenge 0.0042 0.0062 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0481 0.1421 0.4003
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0091 0.0214 0.0212
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0004 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.0251 0.025
Plasmodium vivax unspecified product 0.0249 0.0702 0.2742
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0024 0.0006 0.0007
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0092 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0001 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Echinococcus granulosus jumonji domain containing protein 0.0102 0.0248 0.0247
Giardia lamblia PHD finger protein 15 0.0073 0.0159 0.0433
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0092 0.009
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Mycobacterium tuberculosis Probable dehydrogenase 0.0177 0.0482 0.3507
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0074 0.0074
Toxoplasma gondii cathepsin CPC2 0.0232 0.0651 0.1828
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0013 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Brugia malayi tailless protein 0.0092 0.0217 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.0037
Loa Loa (eye worm) glutathione reductase 0.0078 0.0173 0.0172
Brugia malayi hypothetical protein 0.0504 0.1494 0.1493
Brugia malayi Papain family cysteine protease containing protein 0.0481 0.1421 0.1419
Plasmodium vivax unspecified product 0.0232 0.0651 0.2542
Schistosoma mansoni tyrosine kinase 0.0591 0.1763 0.1762
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0092 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Brugia malayi cathepsin F-like cysteine proteinase 0.0232 0.0651 0.065
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0119 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus multilocularis neuropeptide receptor A26 0.0917 0.2771 0.277
Echinococcus multilocularis dnaJ subfamily B 0.0794 0.239 0.2389
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0024 0.0005 0.0004
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0025 0.0009 0.0036
Onchocerca volvulus 0.0845 0.2549 1
Loa Loa (eye worm) beta-lactamase 0.0062 0.0123 0.0122
Loa Loa (eye worm) transcription factor SMAD2 0.0393 0.1149 0.1148
Echinococcus granulosus cathepsin b 0.3252 1 1
Schistosoma mansoni hypothetical protein 0.061 0.182 0.1819
Echinococcus multilocularis PHD finger protein rhinoceros 0.0073 0.0159 0.0158
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0232 0.0651 0.065
Echinococcus granulosus cathepsin b 0.3252 1 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Brugia malayi Nuclear hormone receptor E75 0.0092 0.0217 0.0216
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0232 0.0651 0.065
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0232 0.0651 0.065
Schistosoma mansoni tyrosine kinase 0.0355 0.1032 0.1031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0044 0.0043
Brugia malayi orphan nuclear receptor NR2E1 0.0092 0.0217 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0059 0.0166
Echinococcus multilocularis cathepsin L 0.0232 0.0651 0.065
Brugia malayi hypothetical protein 0.0333 0.0963 0.0962
Toxoplasma gondii thioredoxin reductase 0.0078 0.0173 0.0478
Schistosoma mansoni sex comb on midleg homolog 0.008 0.0179 0.0178
Mycobacterium ulcerans hydrolase 0.0053 0.0096 0.0677
Loa Loa (eye worm) bromodomain containing protein 0.0044 0.007 0.0068
Echinococcus multilocularis transcription factor Dp 1 0.0026 0.0014 0.0013
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0948 0.2867 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.0536 0.0535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0063 0.0167
Brugia malayi jmjC domain containing protein 0.024 0.0675 0.0674
Schistosoma mansoni smad 0.0027 0.0015 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.0542 0.054
Brugia malayi Pre-SET motif family protein 0.0546 0.1621 0.162
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0015 0.0014
Giardia lamblia Hypothetical protein 0.0053 0.0096 0.0255
Giardia lamblia Cathepsin B precursor 0.1166 0.3542 1
Plasmodium falciparum serine repeat antigen 5 0.0232 0.0651 0.2542
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0046 0.0074 0.0072
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0249 0.0702 0.0701
Onchocerca volvulus 0.0117 0.0293 0.1129
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Giardia lamblia Hypothetical protein 0.0232 0.0651 0.1824
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0025 0.0024
Loa Loa (eye worm) doublecortin family protein 0.003 0.0026 0.0024
Schistosoma mansoni hypothetical protein 0.0068 0.0143 0.0142
Echinococcus multilocularis peregrin 0.0079 0.0177 0.0176
Brugia malayi mbt repeat family protein 0.008 0.0179 0.0178
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0015 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0197 0.0542 0.054
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0024
Trypanosoma cruzi cysteine peptidase, putative 0.0957 0.2894 0.2894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Schistosoma mansoni tyrosine kinase 0.1112 0.3375 0.3374
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0016 0.0014
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0027 0.0016 0.0033
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.003 0.0025 0.0024
Brugia malayi hypothetical protein 0.0103 0.0251 0.025
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.003 0.0025 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Echinococcus multilocularis beta LACTamase domain containing family member 0.0062 0.0123 0.0122
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0063 0.0162
Brugia malayi beta-lactamase 0.0062 0.0123 0.0122
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Brugia malayi MH1 domain containing protein 0.0027 0.0015 0.0014
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.024 0.0675 0.0674
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0176 0.0478 0.0477
Schistosoma mansoni nuclear receptor nhr-48 0.0092 0.0217 0.0216
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.008 0.0179 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0845 0.2549 0.7196
Brugia malayi fibroinase precursor 0.0232 0.0651 0.065
Brugia malayi photoreceptor-specific nuclear receptor 0.0195 0.0536 0.0535
Brugia malayi MAP kinase sur-1 0.0051 0.0092 0.009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.0651 0.1824
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0249 0.0702 0.0701
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0195 0.0536 0.0535
Echinococcus multilocularis lamin dm0 0.0024 0.0006 0.0005
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0005 0.0004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0092 0.0217 0.0216
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0014
Echinococcus granulosus RUN 0.003 0.0026 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.0536 0.0535
Brugia malayi hypothetical protein 0.0036 0.0044 0.0043
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0195 0.0536 0.0535
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0232 0.0651 0.2542
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0005 0.0004
Brugia malayi CXXC zinc finger family protein 0.0097 0.0232 0.0231
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0015 0.0014
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0006 0.0016
Brugia malayi beta-lactamase family protein 0.0062 0.0123 0.0122
Echinococcus multilocularis 0.0344 0.0998 0.0997
Plasmodium falciparum serine repeat antigen 6 0.0232 0.0651 0.2542
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0027 0.0016 0.0046
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Onchocerca volvulus Cathepsin L homolog 0.0232 0.0651 0.2535
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Trypanosoma brucei PAB1-binding protein , putative 0.0043 0.0065 0.0172
Schistosoma mansoni cathepsin S (C01 family) 0.0232 0.0651 0.065
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0103 0.0251 0.025
Trypanosoma cruzi cruzipain precursor, putative 0.0249 0.0702 0.0702
Loa Loa (eye worm) mbt repeat family protein 0.008 0.0179 0.0178
Echinococcus multilocularis polycomb protein SCMH1 0.008 0.0179 0.0178
Echinococcus multilocularis chromobox protein 1 0.0073 0.0159 0.0157
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.003 0.0025 0.0025
Schistosoma mansoni alpha-glucosidase 0.0174 0.0469 0.0468
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0025 0.0071
Leishmania major trypanothione reductase 0.0078 0.0173 0.0489
Brugia malayi Doublecortin family protein 0.003 0.0026 0.0024
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0014
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0018 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0092 0.0217 0.0829
Brugia malayi nuclear hormone receptor family member odr-7 0.0092 0.0217 0.0216
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0012 0.0012
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0232 0.0651 0.2542
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0069 0.0193
Schistosoma mansoni cathepsin F (C01 family) 0.0597 0.178 0.1779
Plasmodium falciparum JmjC domain-containing protein, putative 0.0024 0.0005 0.0005
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0006 0.0007
Trichomonas vaginalis esterase, putative 0.0062 0.0123 0.0348
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0005 0.0004
Plasmodium vivax vivapain-1 0.0481 0.1421 0.5565
Schistosoma mansoni survival motor neuron protein 0.0051 0.009 0.0089
Schistosoma mansoni glutaminase 0.0206 0.0569 0.0567
Giardia lamblia Hypothetical protein 0.0232 0.0651 0.1824
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0028 0.0018 0.0039
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0028 0.0018 0.2347
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0202 0.0556 0.0555
Toxoplasma gondii preprocathepsin c precursor, putative 0.0232 0.0651 0.1828
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Loa Loa (eye worm) hypothetical protein 0.0123 0.0313 0.0311
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.0239 0.0237
Brugia malayi hypothetical protein 0.0092 0.0217 0.0216
Echinococcus multilocularis musashi 0.0024 0.0006 0.0005
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0062 0.0125 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0013 0.0037
Schistosoma mansoni rab6-interacting 0.003 0.0026 0.0024
Schistosoma mansoni hypothetical protein 0.0073 0.0159 0.0158
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0187 0.0186
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0016 0.0016
Trypanosoma cruzi polo-like protein kinase, putative 0.0071 0.0154 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Brugia malayi Heterochromatin protein 1 0.0073 0.0159 0.0157
Entamoeba histolytica cysteine proteinase 2 0.0481 0.1421 0.4948
Mycobacterium leprae Probable lipase LipE 0.0062 0.0123 0.0877
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0275 0.0784 0.0782
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.003 0.0025 0.0024
Plasmodium vivax ataxin-2 like protein, putative 0.0043 0.0065 0.0239
Schistosoma mansoni Smad4 0.0027 0.0015 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Brugia malayi Bromodomain containing protein 0.0079 0.0177 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Echinococcus granulosus ubiquitin specific protease 41 0.003 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0126 0.0321 0.032
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0123 0.0348
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Trypanosoma cruzi major cysteine proteinase, putative 0.0232 0.0651 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0059 0.0166
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0231 0.0649 0.0648
Leishmania major hypothetical protein, conserved 0.0062 0.0123 0.0349
Trypanosoma cruzi cysteine peptidase, putative 0.0957 0.2894 0.2894
Loa Loa (eye worm) hypothetical protein 0.0243 0.0684 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0043 0.012
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0195 0.0536 0.0535
Brugia malayi steroid hormone receptor 0.0195 0.0536 0.0535
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0232 0.0651 0.2542
Brugia malayi glutathione reductase 0.0078 0.0173 0.0172
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0395 0.1154 0.8443
Schistosoma mansoni tyrosine kinase 0.0591 0.1763 0.1762
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0018 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0232 0.0651 0.065
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0071 0.0154 0.0433
Plasmodium falciparum cysteine proteinase falcipain 1 0.0481 0.1421 0.5565
Brugia malayi hypothetical protein 0.0052 0.0094 0.0093
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.0491 0.1906
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0075 0.0165 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0232 0.0651 0.1837
Schistosoma mansoni hypothetical protein 0.0794 0.239 0.2389
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0177 0.0482 0.3507
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0176 0.0478 0.0477
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Onchocerca volvulus 0.0032 0.0032 0.01
Echinococcus multilocularis cpg binding protein 0.0107 0.0264 0.0263
Brugia malayi mbt repeat family protein 0.008 0.0179 0.0178
Plasmodium falciparum cysteine proteinase falcipain 3 0.0845 0.2549 1
Schistosoma mansoni microtubule-associated protein tau 0.2248 0.6892 0.6891
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0249 0.0702 0.0701
Schistosoma mansoni inositol monophosphatase 0.0028 0.0018 0.0017
Echinococcus granulosus PHD finger protein rhinoceros 0.0073 0.0159 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni nuclear receptor 0.0092 0.0217 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1166 0.3542 1
Schistosoma mansoni cathepsin C 0.0232 0.0651 0.065
Schistosoma mansoni tsg101-related 0.0044 0.0067 0.0066
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0006 0.0007
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.003 0.0025 0.0024
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Trichomonas vaginalis set domain proteins, putative 0.0621 0.1853 0.5232
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0225 0.0628 0.0626
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0024
Echinococcus granulosus ecdysone induced protein 78C 0.0195 0.0536 0.0535
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Mycobacterium ulcerans arylsulfatase AtsD 0.0053 0.0096 0.0677
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0842
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0062 0.0123 0.0877
Loa Loa (eye worm) hypothetical protein 0.0504 0.1494 0.1493
Brugia malayi hypothetical protein 0.003 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0091 0.0214 0.0212
Treponema pallidum NADH oxidase 0.0027 0.0016 0.0041
Mycobacterium ulcerans arylsulfatase AtsB 0.0053 0.0096 0.0677
Mycobacterium ulcerans esterase/lipase LipP 0.0062 0.0123 0.0877
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Plasmodium vivax vivapain-2 0.0845 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0232 0.0651 0.065
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0232 0.0651 0.2542
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0015 0.0014
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0092 0.0092
Echinococcus multilocularis tar DNA binding protein 0.0225 0.0628 0.0626
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0006 0.0005
Leishmania major alpha glucosidase II subunit, putative 0.0045 0.0071 0.02
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0037 0.0105
Brugia malayi conserved hypotetical protein 0.0092 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.0243 0.0684 0.0683
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0028 0.0018 0.0049
Schistosoma mansoni rab6-interacting 0.003 0.0026 0.0024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0034 0.0033
Trypanosoma brucei ISWI complex protein 0.0038 0.0051 0.0133
Trypanosoma cruzi PAB1-binding protein , putative 0.0043 0.0065 0.0065
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0159 0.0438
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Loa Loa (eye worm) CXXC zinc finger family protein 0.0097 0.0232 0.0231
Entamoeba histolytica cysteine protease, putative 0.0845 0.2549 0.8891
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0063 0.0062
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Schistosoma mansoni hypothetical protein 0.003 0.0026 0.0024
Echinococcus granulosus Polycystic kidney disease protein 0.003 0.0026 0.0024
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0044 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0195 0.0536 0.0535
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0232 0.0651 0.2542
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.0065 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Onchocerca volvulus 0.0504 0.1494 0.585
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Onchocerca volvulus 0.0092 0.0217 0.0829
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0045 0.0071 0.007
Schistosoma mansoni polycystin 1-related 0.003 0.0026 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Trypanosoma cruzi ISWI complex protein 0.0038 0.0051 0.0051
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0323 0.0932 0.0931
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0024 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Loa Loa (eye worm) hypothetical protein 0.0381 0.1112 0.1111
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0119 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0481 0.1421 0.401
Giardia lamblia Encystation-specific protease 0.0232 0.0651 0.1824
Brugia malayi PHD-finger family protein 0.0068 0.0143 0.0142
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0027 0.0016 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0063 0.0063
Leishmania major hypothetical protein, conserved 0.0043 0.0065 0.0183
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0027 0.0016 0.0086
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0092 0.0242
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0232 0.0651 0.065
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Plasmodium falciparum phd finger protein, putative 0.0073 0.0159 0.0609
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0027 0.0016 0.0014
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.0494 0.1461 0.146
Plasmodium falciparum serine repeat antigen 4 0.0232 0.0651 0.2542
Trichomonas vaginalis glutathione reductase, putative 0.0027 0.0016 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0195 0.0536 0.0535
Entamoeba histolytica hypothetical protein 0.0232 0.0651 0.226
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0058
Trypanosoma cruzi PAB1-binding protein , putative 0.0043 0.0065 0.0065
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Onchocerca volvulus 0.0845 0.2549 1
Brugia malayi PHD-finger family protein 0.0034 0.0038 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0006 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.024 0.0675 0.0674
Echinococcus granulosus serine protein kinase ATM 0.003 0.0025 0.0024
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0131 0.0339 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0176 0.0478 0.0477
Brugia malayi latrophilin 2 splice variant baaae 0.0381 0.1112 0.1111
Onchocerca volvulus 0.0333 0.0963 0.3763
Schistosoma mansoni jumonji domain containing protein 0.0191 0.0522 0.0521
Giardia lamblia Cathepsin B precursor 0.1166 0.3542 1
Mycobacterium tuberculosis Probable lipase LipE 0.0062 0.0123 0.0877
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0069 0.0193
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0558 0.1658 0.1657
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Onchocerca volvulus 0.003 0.0026 0.0076
Toxoplasma gondii exonuclease III APE 0.0042 0.0063 0.0167
Brugia malayi Nuclear hormone receptor E75 0.0092 0.0217 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0313 0.0311
Schistosoma mansoni cpg binding protein 0.0107 0.0264 0.0263
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.0651 0.1824
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0063 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.0536 0.0535
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0195 0.0536 0.0535
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Schistosoma mansoni tsg101-related 0.0036 0.0042 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0092 0.0217 0.0216
Toxoplasma gondii cathepsin CPC1 0.0232 0.0651 0.1828
Echinococcus multilocularis transcription factor btf3 0.0026 0.0013 0.0012
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0045 0.0071 0.0199
Trypanosoma cruzi cysteine peptidase, putative 0.0481 0.1421 0.1421
Loa Loa (eye worm) glutaminase 0.0206 0.0569 0.0567
Brugia malayi Papain family cysteine protease containing protein 0.0845 0.2549 0.2548
Brugia malayi RNA, U transporter 1 0.0062 0.0123 0.0122
Brugia malayi AF-10 protein 0.0024 0.0006 0.0005
Schistosoma mansoni lipoxygenase 0.0131 0.0339 0.0338
Loa Loa (eye worm) nuclear hormone receptor 0.0092 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.0597 0.178 0.1779
Leishmania major hypothetical protein, conserved 0.0038 0.0051 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0005 0.0004
Brugia malayi cathepsin L-like cysteine proteinase 0.0232 0.0651 0.065
Loa Loa (eye worm) TK/INSR protein kinase 0.0355 0.1032 0.1031
Brugia malayi Pre-SET motif family protein 0.008 0.018 0.0179
Echinococcus multilocularis thyroid hormone receptor alpha 0.0195 0.0536 0.0535
Onchocerca volvulus Cathepsin L homolog 0.0845 0.2549 1
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Brugia malayi nuclear hormone receptor family member nhr-6 0.0092 0.0217 0.0216
Echinococcus granulosus transcription factor btf3 0.0026 0.0013 0.0012
Echinococcus multilocularis smad 0.0027 0.0015 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Trichomonas vaginalis inositol monophosphatase, putative 0.0028 0.0018 0.005
Giardia lamblia Kinase, PLK 0.0071 0.0154 0.0417
Echinococcus granulosus intermediate filament protein 0.0024 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Echinococcus granulosus lipoxygenase domain containing protein 0.003 0.0026 0.0024
Toxoplasma gondii cathepsin CPL 0.0845 0.2549 0.7193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Plasmodium falciparum serine repeat antigen 3 0.0232 0.0651 0.2542
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0063 0.0062
Brugia malayi Bromodomain containing protein 0.0194 0.0533 0.0531
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0006 0.0006
Echinococcus multilocularis cathepsin b 0.3252 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0542 0.054
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Plasmodium vivax vivapain-2 0.0845 0.2549 1
Echinococcus granulosus lipoxygenase domain containing protein 0.003 0.0026 0.0024
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0013 0.0033
Treponema pallidum fructose-bisphosphate aldolase 0.0948 0.2867 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus granulosus neuropeptide s receptor 0.0917 0.2771 0.277
Schistosoma mansoni tyrosine kinase 0.0591 0.1763 0.1762
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.0037
Brugia malayi Cathepsin L-like precursor 0.0597 0.178 0.1779
Schistosoma mansoni lamin 0.0024 0.0006 0.0005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0195 0.0536 0.0535
Echinococcus multilocularis neuropeptide s receptor 0.0917 0.2771 0.277
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0038 0.0051 0.005
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0005 0.0004
Onchocerca volvulus Cathepsin L homolog 0.0845 0.2549 1
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Plasmodium vivax serine-repeat antigen (SERA) 0.0232 0.0651 0.2542
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0016 0.0016
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0044
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0232 0.0651 0.2542
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0123 0.0123
Trypanosoma brucei cysteine peptidase C (CPC) 0.1166 0.3542 1
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Loa Loa (eye worm) fibroinase 0.0845 0.2549 0.2548
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0069 0.0246
Loa Loa (eye worm) cathepsin B 0.1166 0.3542 0.3542
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0195 0.0536 0.0535
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.0542 0.054
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0062 0.0123 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Brugia malayi cathepsin L-like precursor 0.0597 0.178 0.1779
Toxoplasma gondii ABC1 family protein 0.0062 0.0123 0.0337
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0177 0.0482 0.3507
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0131 0.0339 0.0338
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Loa Loa (eye worm) hypothetical protein 0.0249 0.0702 0.0701
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0195 0.0536 0.0535
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0195 0.0536 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0195 0.0536 0.0535
Echinococcus granulosus mixed lineage leukemia protein mll 0.0027 0.0016 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0062 0.0123 0.0877
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0053 0.0096 0.0271
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0842
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0045 0.0071 0.0189
Brugia malayi Cathepsin L-like cysteine proteinase 0.0597 0.178 0.1779
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0006 0.0005
Schistosoma mansoni ap endonuclease 0.0042 0.0063 0.0062
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0195 0.0536 0.0535
Brugia malayi Thioredoxin reductase 0.0078 0.0173 0.0172
Echinococcus granulosus epidermal growth factor receptor 0.1112 0.3375 0.3374
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0092 0.009
Brugia malayi RNA recognition motif domain containing protein 0.0225 0.0628 0.0626
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0044 0.0043
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0355 0.1032 0.1031
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.003 0.0025 0.0024
Echinococcus granulosus cathepsin L cysteine proteinase 0.0845 0.2549 0.2548
Trichomonas vaginalis penicillin-binding protein, putative 0.0062 0.0123 0.0348
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Leishmania major cysteine peptidase A (CPA) 0.0845 0.2549 0.7196
Schistosoma mansoni chromobox protein 0.0073 0.0159 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0062 0.0123 0.0122
Schistosoma mansoni intermediate filament proteins 0.0024 0.0006 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0119 0.0117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0092 0.0217 0.0216
Brugia malayi RNA binding protein 0.0225 0.0628 0.0626
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0195 0.0536 0.0535
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0159 0.0447
Brugia malayi nuclear hormone receptor 0.0092 0.0217 0.0216
Echinococcus granulosus thyroid hormone receptor alpha 0.0092 0.0217 0.0216
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0842
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0323 0.0932 0.0931
Brugia malayi Steroid receptor seven-up type 2 0.0195 0.0536 0.0535
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0027 0.0016 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0045 0.0071 0.0199
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0217 0.0216
Echinococcus granulosus FTZ F1 alpha 0.0195 0.0536 0.0535
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0521 0.147
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Plasmodium falciparum ataxin-2 like protein, putative 0.0043 0.0065 0.0239
Echinococcus granulosus snurportin 1 0.0231 0.0649 0.0648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0063 0.0233
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0025 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Plasmodium vivax unspecified product 0.0481 0.1421 0.5565
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0045 0.0071 0.0233
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0005 0.0004
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0119 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0195 0.0536 0.0535
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0036 0.0042 0.0134
Echinococcus granulosus cathepsin L cysteine protease 0.0481 0.1421 0.1419
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Loa Loa (eye worm) TAR-binding protein 0.0225 0.0628 0.0626
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0208 0.0577 0.0576
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Onchocerca volvulus 0.0845 0.2549 1
Leishmania major cathepsin L-like protease 0.0957 0.2894 0.817
Echinococcus granulosus cathepsin L 0.0481 0.1421 0.1419
Schistosoma mansoni lozenge 0.0042 0.0062 0.006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.003 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0232 0.0651 0.1837
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0546 0.1621 0.162
Brugia malayi hypothetical protein 0.003 0.0026 0.0024
Schistosoma mansoni inositol monophosphatase 0.0028 0.0018 0.0017
Echinococcus multilocularis microtubule associated protein 2 0.2248 0.6892 0.6891
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0006 0.0005
Brugia malayi serine/threonine-protein kinase plk-2 0.0071 0.0154 0.0152
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0845 0.2549 0.2548
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0062 0.0123 0.0122
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.0065 0.0064
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0043 0.0065 0.0064
Brugia malayi Inositol-1 0.0028 0.0018 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0123 0.0348
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0046 0.0074 0.0072
Schistosoma mansoni myelin transcription factor 1 myt1 0.0091 0.0214 0.0212
Schistosoma mansoni lipoxygenase 0.0077 0.0171 0.017
Brugia malayi jmjC domain containing protein 0.0099 0.0239 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0651 0.1837
Echinococcus granulosus phd:f box containing protein 0.0024 0.0005 0.0004
Loa Loa (eye worm) Smad1 0.0027 0.0015 0.0014
Brugia malayi hypothetical protein 0.0028 0.0018 0.0017
Schistosoma mansoni cathepsin F (C01 family) 0.0845 0.2549 0.2548
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus multilocularis GPCR, family 2 0.0176 0.0478 0.0477
Echinococcus granulosus chromobox protein 1 0.0073 0.0159 0.0157
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0046 0.0074 0.0208
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus multilocularis snurportin 1 0.0231 0.0649 0.0648
Plasmodium vivax glutathione reductase, putative 0.0078 0.0173 0.0664
Brugia malayi cathepsin Z-like cysteine proteinase 0.0232 0.0651 0.065
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Schistosoma mansoni hypothetical protein 0.0231 0.0649 0.0648
Echinococcus multilocularis lipoxygenase domain containing protein 0.003 0.0026 0.0024
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0187 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Onchocerca volvulus 0.0845 0.2549 1
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0159 0.0609
Brugia malayi hypothetical protein 0.025 0.0705 0.0704
Onchocerca volvulus 0.0232 0.0651 0.2535
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0333 0.0963 0.0962
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0092 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.018 0.0179
Schistosoma mansoni hypothetical protein 0.0051 0.009 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0481 0.1421 0.4003
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0014
Trypanosoma brucei glucosidase, putative 0.0045 0.0071 0.0189
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3252 1 1
Echinococcus multilocularis jumonji domain containing protein 0.0102 0.0248 0.0247
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0045 0.0071 0.0199
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0045 0.0071 0.0233
Echinococcus multilocularis cathepsin L 0.0481 0.1421 0.1419
Loa Loa (eye worm) TK/EGFR protein kinase 0.1112 0.3375 0.3374
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0027 0.0016 0.0046
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0006 0.0005
Onchocerca volvulus 0.0097 0.0232 0.0888
Echinococcus granulosus polycomb protein SCMH1 0.008 0.0179 0.0178
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0708 0.2125 0.2125
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0027 0.0016 0.197
Trichomonas vaginalis mercuric reductase, putative 0.0027 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Echinococcus multilocularis Polycystic kidney disease protein 0.003 0.0026 0.0024
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0855 0.2579 0.2578
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0187 0.0186
Trypanosoma cruzi cysteine peptidase, putative 0.0957 0.2894 0.2894
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus multilocularis survival motor neuron protein 1 0.025 0.0705 0.0704
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0037 0.0036
Echinococcus granulosus lamin 0.0024 0.0006 0.0005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0078 0.0173 0.1241
Loa Loa (eye worm) latrophilin receptor protein 2 0.0176 0.0478 0.0477
Schistosoma mansoni cathepsin s 0.0249 0.0702 0.0701
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Onchocerca volvulus Serine\/threonine kinase homolog 0.0071 0.0154 0.0579
Echinococcus granulosus methyl CpG binding domain protein 2 0.0043 0.0065 0.0064
Echinococcus granulosus muscleblind protein 0.0243 0.0684 0.0683
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0232 0.0651 0.065
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0024 0.0006 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0123 0.0348
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.0313 0.0311
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0195 0.0536 0.0535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Brugia malayi hypothetical protein 0.1774 0.5425 0.5424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Schistosoma mansoni zinc finger protein 0.0055 0.0102 0.01
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0063 0.0178
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0249 0.0702 0.0701
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0063 0.0233
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.008 0.018 0.0179
Loa Loa (eye worm) RNA binding protein 0.0225 0.0628 0.0626
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Onchocerca volvulus 0.0845 0.2549 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0845 0.2549 0.2548
Echinococcus multilocularis SAM and MBT domain containing protein 0.008 0.0179 0.0178
Plasmodium falciparum ataxin-2 like protein, putative 0.0043 0.0065 0.0239
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0463 0.1366 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus granulosus cathepsin l1 0.0597 0.178 0.1779
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Brugia malayi TAR-binding protein 0.0225 0.0628 0.0626
Loa Loa (eye worm) hypothetical protein 0.3252 1 1
Brugia malayi Cathepsin L-like precursor 0.0597 0.178 0.1779
Brugia malayi nuclear receptor NHR-88 0.0092 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0064
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Echinococcus granulosus insulin receptor 0.0355 0.1032 0.1031
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0016 0.0014
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0463 0.1366 1
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0052 0.0094 0.0093
Echinococcus granulosus cathepsin L 0.0232 0.0651 0.065
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0006 0.0005
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0092 0.0217 0.0216
Mycobacterium tuberculosis Probable lipase LipD 0.0062 0.0123 0.0877
Echinococcus multilocularis epidermal growth factor receptor 0.1112 0.3375 0.3374
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0155 0.0414 0.0412
Schistosoma mansoni nuclear receptor 0.0092 0.0217 0.0216
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.0542 0.054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0313 0.0311
Brugia malayi ecdysone receptor 0.0092 0.0217 0.0216
Plasmodium falciparum serine repeat antigen 1 0.0232 0.0651 0.2542
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0232 0.0651 0.1824
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Echinococcus granulosus Smad4 0.0027 0.0015 0.0014
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0845 0.2549 1
Toxoplasma gondii NADPH-glutathione reductase 0.0027 0.0016 0.0033
Echinococcus multilocularis RUN 0.003 0.0026 0.0024
Plasmodium vivax thioredoxin reductase, putative 0.0078 0.0173 0.0664
Schistosoma mansoni hypothetical protein 0.0036 0.0044 0.0043
Brugia malayi Protein kinase domain containing protein 0.0355 0.1032 0.1031
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Loa Loa (eye worm) hypothetical protein 0.0558 0.1658 0.1657
Trypanosoma brucei protein kinase, putative 0.0051 0.0092 0.0247
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.0651 0.1837
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.003 0.0025 0.006
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0006 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.0195 0.0536 0.2082
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.0651 0.065
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0275 0.0784 0.0782
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0046 0.0074 0.0243
Loa Loa (eye worm) hypothetical protein 0.0597 0.178 0.1779
Onchocerca volvulus 0.003 0.0026 0.0076
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0046 0.0074 0.0072
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0176 0.0478 0.0477
Brugia malayi Nuclear hormone receptor-like 1 0.0195 0.0536 0.0535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0159 0.0157
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0521 0.147
Schistosoma mansoni tyrosine kinase 0.0355 0.1032 0.1031
Onchocerca volvulus 0.0062 0.0123 0.0461
Schistosoma mansoni hypothetical protein 0.0024 0.0006 0.0005
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0092 0.0247
Schistosoma mansoni coup transcription factor 0.0195 0.0536 0.0535
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0195 0.0536 0.0535
Schistosoma mansoni tsg101-related 0.0044 0.0067 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Plasmodium falciparum serine repeat antigen 2 0.0232 0.0651 0.2542
Brugia malayi MH2 domain containing protein 0.0027 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.0037
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0598 0.1782 0.1781
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0176 0.0478 0.0477
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0006 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0119 0.0117
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3252 1 1
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0053 0.0096 0.0677
Brugia malayi hypothetical protein 0.0053 0.0096 0.0095
Schistosoma mansoni chromobox protein 0.0073 0.0159 0.0157
Loa Loa (eye worm) glutaminase 2 0.0206 0.0569 0.0567
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0062 0.0123 0.0877
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0062 0.0123 0.0122
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0037 0.0036
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0005 0.0005
Schistosoma mansoni transcription factor btf3 0.0026 0.0013 0.0012
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0027 0.0016 0.0014
Brugia malayi cathepsin L precursor 0.0232 0.0651 0.065
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0062 0.0125 0.0123
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Mycobacterium ulcerans hypothetical protein 0.0062 0.0123 0.0877
Loa Loa (eye worm) PHD-finger family protein 0.0052 0.0093 0.0091
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.0536 0.0535
Echinococcus granulosus nuclear receptor nhr 48 0.0092 0.0217 0.0216
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0043 0.012
Onchocerca volvulus 0.0092 0.0217 0.0829
Brugia malayi MH2 domain containing protein 0.0393 0.1149 0.1148
Schistosoma mansoni nuclear hormone receptor 0.0092 0.0217 0.0216
Entamoeba histolytica hypothetical protein 0.003 0.0025 0.0074
Loa Loa (eye worm) hypothetical protein 0.0751 0.2257 0.2256
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.003 0.0025 0.0024
Plasmodium vivax vivapain-3 0.0481 0.1421 0.5565
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0195 0.0536 0.0535
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.009 0.0212 0.021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0195 0.0536 0.0535
Brugia malayi PHD-finger family protein 0.0073 0.0159 0.0158
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.0239 0.0237
Loa Loa (eye worm) hypothetical protein 0.0102 0.0249 0.0248
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0063 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0597 0.178 0.5024
Schistosoma mansoni cathepsin B (C01 family) 0.0232 0.0651 0.065
Entamoeba histolytica cysteine proteinase, putative 0.0845 0.2549 0.8891
Trypanosoma cruzi cruzipain precursor, putative 0.0957 0.2894 0.2894
Mycobacterium tuberculosis Probable reductase 0.0177 0.0482 0.3507
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Conserved protein 0.0062 0.0123 0.0877
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0481 0.1421 0.1421
Trypanosoma brucei hypothetical protein, conserved 0.0062 0.0123 0.0337
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Echinococcus granulosus epidermal growth factor receptor 0.0598 0.1782 0.1781
Loa Loa (eye worm) hypothetical protein 0.0845 0.2549 0.2548
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0092 0.0217 0.0829
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0015 0.0014
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.0313 0.0311
Giardia lamblia Cathepsin L-like protease 0.0232 0.0651 0.1824
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Mycobacterium ulcerans sulfatase 0.0053 0.0096 0.0677
Echinococcus granulosus lysosomal alpha glucosidase 0.0202 0.0556 0.0555
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0062 0.0123 0.0877
Brugia malayi ecdysteroid receptor 0.0195 0.0536 0.0535
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Plasmodium vivax serine-repeat antigen (SERA) 0.0232 0.0651 0.2542
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0195 0.0536 0.0535
Loa Loa (eye worm) steroid hormone receptor 0.0195 0.0536 0.0535
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.008 0.018 0.0498
Loa Loa (eye worm) hypothetical protein 0.0053 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0232 0.0651 0.226
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.0251 0.025
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0062 0.0123 0.0877
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0071 0.0071
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0177 0.0482 0.3507
Schistosoma mansoni thyroid hormone receptor 0.0195 0.0536 0.0535
Schistosoma mansoni hypothetical protein 0.0381 0.1112 0.1111
Brugia malayi Calcitonin receptor-like protein seb-1 0.0558 0.1658 0.1657
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) hypothetical protein 0.0082 0.0187 0.0186
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Mycobacterium ulcerans arylsulfatase, AslA 0.0053 0.0096 0.0677
Echinococcus granulosus GPCR family 2 0.0176 0.0478 0.0477
Toxoplasma gondii cathepsin B 0.1166 0.3542 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0151 0.04 0.0399
Schistosoma mansoni cpg binding protein 0.0097 0.0232 0.0231
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0059 0.0208
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0481 0.1421 0.1419
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0103 0.0251 0.025
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0177 0.0482 0.3507
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Brugia malayi nuclear receptor NHR-67 0.0092 0.0217 0.0216
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Echinococcus multilocularis epidermal growth factor receptor 0.0598 0.1782 0.1781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0092 0.0092
Mycobacterium ulcerans arylsulfatase AtsD 0.0053 0.0096 0.0677
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0005 0.0004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0195 0.0536 0.2082
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0195 0.0536 0.0535
Loa Loa (eye worm) histone methyltransferase 0.0033 0.0034 0.0033
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0197 0.0543 0.3957
Trypanosoma brucei trypanothione reductase 0.0078 0.0173 0.0478
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0046 0.0074 0.0072
Echinococcus granulosus survival motor neuron protein 1 0.025 0.0705 0.0704
Brugia malayi cathepsin F-like cysteine proteinase 0.0249 0.0702 0.0701
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0232 0.0651 0.2542
Echinococcus granulosus histone acetyltransferase MYST2 0.0091 0.0214 0.0212
Echinococcus granulosus inositol monophosphatase 1 0.0028 0.0018 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0195 0.0536 0.0535
Plasmodium falciparum serine repeat antigen 8 0.0232 0.0651 0.2542
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0025 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0063 0.0435
Schistosoma mansoni hypothetical protein 0.0052 0.0093 0.0091
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0006 0.0017
Loa Loa (eye worm) thioredoxin reductase 0.0078 0.0173 0.0172
Echinococcus granulosus beta LACTamase domain containing family member 0.0062 0.0123 0.0122
Brugia malayi Glycosyl hydrolases family 31 protein 0.0045 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Echinococcus granulosus thioredoxin glutathione reductase 0.0078 0.0173 0.0172
Trichomonas vaginalis hypothetical protein 0.0025 0.0011 0.0031
Echinococcus granulosus zinc finger protein 0.0055 0.0102 0.01
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0195 0.0536 0.0535
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0006 0.0007
Onchocerca volvulus Cathepsin F homolog 0.0845 0.2549 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.003 0.0025 0.0055
Loa Loa (eye worm) PHD-finger family protein 0.0073 0.0159 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.0536 0.0535
Onchocerca volvulus 0.0845 0.2549 1
Schistosoma mansoni tyrosine kinase 0.0598 0.1782 0.1781
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0597 0.178 0.6202
Brugia malayi Latrophilin receptor protein 2 0.0176 0.0478 0.0477
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0063 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Echinococcus multilocularis lysosomal alpha glucosidase 0.0202 0.0556 0.0555
Toxoplasma gondii LsmAD domain-containing protein 0.0043 0.0065 0.0172
Brugia malayi Cathepsin L-like precursor 0.0249 0.0702 0.0701
Echinococcus granulosus cysteine protease 0.0481 0.1421 0.1419
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0013 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Echinococcus granulosus tar DNA binding protein 0.0225 0.0628 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0232 0.0651 0.226
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0004
Onchocerca volvulus 0.0062 0.0123 0.0461
Echinococcus granulosus cathepsin l cysteine peptidase 0.0845 0.2549 0.2548
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0197 0.0543 0.3957
Echinococcus multilocularis cysteine protease 0.0845 0.2549 0.2548
Loa Loa (eye worm) hypothetical protein 0.0333 0.0963 0.0962
Leishmania major cathepsin L-like protease 0.0957 0.2894 0.817
Brugia malayi nuclear receptor RXR 0.0103 0.0251 0.025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus granulosus fetal alzheimer antigen falz 0.0062 0.0125 0.0123
Onchocerca volvulus 0.0062 0.0123 0.0461
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0027 0.0016 0.0046

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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