Detailed information for compound 677905

Basic information

Technical information
  • TDR Targets ID: 677905
  • Name: 2-(2-acetylphenoxy)-1-(4-methylphenyl)ethanon e
  • MW: 268.307 | Formula: C17H16O3
  • H donors: 0 H acceptors: 2 LogP: 3.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)C(=O)COc1ccccc1C(=O)C
  • InChi: 1S/C17H16O3/c1-12-7-9-14(10-8-12)16(19)11-20-17-6-4-3-5-15(17)13(2)18/h3-10H,11H2,1-2H3
  • InChiKey: PAJHHSKWGUBJFU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-ethanoylphenoxy)-1-(4-methylphenyl)ethanone
  • ZINC00473690
  • STK275265

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.029 0.029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.013 0.0376
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.029 0.0378
Schistosoma mansoni sodium/chloride dependent transporter 0.0295 0.37 0.4823
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0167 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0344 0.0687
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.015 0.0915
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0047 0.0061
Brugia malayi nuclear hormone receptor 0.0014 0.0089 0.0177
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0384 0.1116
Plasmodium vivax hypothetical protein, conserved 0.0039 0.041 0.5915
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0133 0.1622 1
Trichomonas vaginalis set domain proteins, putative 0.0244 0.3039 0.6079
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0222 0.0442
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0223 0.1724
Echinococcus multilocularis Smad4 0.0016 0.0112 0.0112
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0311 0.2404
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0143 0.2048
Loa Loa (eye worm) hypothetical protein 0.0128 0.1552 0.2024
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0089 0.0116
Schistosoma mansoni hypothetical protein 0.0604 0.7671 1
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.3497
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.029 0.0378
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.029 0.0579
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0089 0.0177
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0604 0.7671 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0675 0.0879
Loa Loa (eye worm) hypothetical protein 0.0037 0.0384 0.05
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0222 0.0251
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0044 0.0088
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0384 0.0766
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.1103
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0243 0.0484
Onchocerca volvulus 0.0007 0.0001 0.0002
Loa Loa (eye worm) type III restriction enzyme 0.0016 0.0113 0.0148
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0026 0.0243 0.0317
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Loa Loa (eye worm) hypothetical protein 0.0037 0.0384 0.05
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.2941 0.8574
Echinococcus multilocularis FTZ F1 alpha 0.003 0.029 0.029
Brugia malayi beta-lactamase 0.0037 0.0384 0.0766
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.1103
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0558 0.0558
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0396 0.4998 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0001 0.0001
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0197 0.2435 0.2771
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.029 0.0378
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0396 0.4998 1
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.1202 0.1566
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0026 0.0243 0.0317
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.015 0.0915
Echinococcus multilocularis tumor protein p63 0.0347 0.4362 0.4362
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0044 0.0058
Loa Loa (eye worm) hypothetical protein 0.0018 0.0143 0.0186
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.2023 0.4048
Brugia malayi hypothetical protein 0.0014 0.0089 0.0177
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0558 0.0558
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0553 0.0721
Loa Loa (eye worm) hypothetical protein 0.0024 0.0222 0.0289
Brugia malayi nuclear receptor NHR-88 0.0014 0.0089 0.0177
Echinococcus multilocularis transcription factor btf3 0.0034 0.0344 0.0344
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0267 0.0348
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0026 0.0243 0.3497
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0222 0.0442
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.1289 0.2576
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0222 0.1361
Trichomonas vaginalis ran, putative 0.0021 0.018 0.0357
Echinococcus granulosus smad 0.0016 0.0112 0.0146
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.013 0.1864
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0243 0.1492
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0057 0.0113
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0061 0.0693 0.4268
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0243 0.0484
Brugia malayi Cytochrome P450 family protein 0.0016 0.0112 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.029 0.0378
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0396 0.4998 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.041 0.0819
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.029 0.029
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0744 0.1487
Echinococcus granulosus SPRY domain containing protein 0.0016 0.0113 0.0147
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0122 0.1478 0.911
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0143 0.0413
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0222 0.0251
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0682 0.0889
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0134 0.1627 0.3247
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.029 0.0378
Leishmania major basic transcription factor 3a, putative 0.0034 0.0344 0.2118
Trichomonas vaginalis esterase, putative 0.0037 0.0384 0.0766
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0105 0.1256 0.1637
Plasmodium vivax serine/threonine kinase-1, putative 0.0061 0.0693 1
Plasmodium falciparum phosphodiesterase delta, putative 0.0026 0.0243 0.3497
Loa Loa (eye worm) hypothetical protein 0.0295 0.37 0.4823
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0553 0.0721
Loa Loa (eye worm) hypothetical protein 0.0037 0.0384 0.05
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.3131 0.4082
Schistosoma mansoni smad1 5 8 and 0.0016 0.0112 0.0146
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.011 0.022
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0112 0.0146
Brugia malayi MH1 domain containing protein 0.0016 0.0112 0.0224
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0223 0.3207
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Loa Loa (eye worm) steroid hormone receptor 0.003 0.029 0.0378
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.015 0.0433
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0499 0.307
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0384 0.1116
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0065 0.0744 0.097
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Loa Loa (eye worm) hypothetical protein 0.0016 0.0113 0.0148
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0274 0.343 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.1627 0.2121
Loa Loa (eye worm) hypothetical protein 0.0016 0.0113 0.0147
Brugia malayi nuclear hormone receptor 0.003 0.029 0.0579
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.1202 0.7404
Leishmania major hypothetical protein, conserved 0.0122 0.1478 0.911
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.1627 0.2121
Echinococcus multilocularis dna polymerase kappa 0.0019 0.015 0.015
Brugia malayi mbt repeat family protein 0.005 0.0558 0.1113
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0553 0.0721
Plasmodium falciparum DNA repair and recombination protein RAD54, putative 0.0016 0.0113 0.162
Loa Loa (eye worm) hypothetical protein 0.001 0.0044 0.0058
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0133 0.1622 1
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Trypanosoma brucei DNA repair and recombination protein RAD54, putative 0.0016 0.0113 0.0691
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0384 0.0766
Brugia malayi nuclear receptor RXR 0.0014 0.0089 0.0177
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0553 0.0721
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.4999 0.4999
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0384 0.2361
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0396 0.4998 0.5688
Loa Loa (eye worm) hypothetical protein 0.0147 0.1795 0.2339
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Plasmodium vivax transportin, putative 0.0011 0.0047 0.0661
Loa Loa (eye worm) hypothetical protein 0.0016 0.011 0.0144
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.015 0.0195
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.0721
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0222 0.0442
Echinococcus multilocularis 0.0016 0.0113 0.0113
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus granulosus dna polymerase eta 0.0019 0.015 0.0195
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0499 0.0996
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.1622 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0222 0.0442
Loa Loa (eye worm) hypothetical protein 0.005 0.0558 0.0727
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0122 0.0159
Onchocerca volvulus 0.0147 0.1795 0.359
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0112 0.0146
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.1202 0.9323
Loa Loa (eye worm) nuclear factor I 0.0009 0.0022 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.1202 0.2402
Toxoplasma gondii hypothetical protein 0.005 0.0553 0.4285
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0105 0.1256 0.1256
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0026 0.0243 0.0317
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0094 0.1121 0.691
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0016 0.0113 0.0691
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0013 0.0016
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.018 0.1102
Plasmodium vivax importin-beta 2, putative 0.0057 0.0636 0.9182
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0648 0.0844
Schistosoma mansoni DNA helicase recq5 0.001 0.0044 0.0058
Echinococcus granulosus DNA repair and recombination protein RAD54B 0.0016 0.0113 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0243 0.1492
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0243 0.0484
Trypanosoma cruzi ISWI complex protein 0.0015 0.01 0.0611
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0089 0.0116
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.015 0.0297
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.011 0.022
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0396 0.4998 0.5667
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0126 0.1524 0.1986
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.018 0.1102
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.005 0.005
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0112 0.0681
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0026 0.0243 0.0243
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.029 0.0378
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0243 0.1492
Toxoplasma gondii ABC1 family protein 0.0037 0.0384 0.2973
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0089 0.0116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0368 0.0368
Entamoeba histolytica Ran family GTPase 0.0021 0.018 0.0203
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0648 0.0844
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0112 0.0112
Echinococcus multilocularis dna polymerase eta 0.0019 0.015 0.015
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.0484
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.029 0.0378
Trypanosoma brucei unspecified product 0.0013 0.0075 0.0456
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0558 0.0727
Echinococcus multilocularis snurportin 1 0.0604 0.7671 0.7671
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.029 0.0579
Brugia malayi hypothetical protein 0.0147 0.1795 0.3581
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0026 0.0243 0.0243
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0523 0.0682
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0105 0.1256 0.9745
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0089 0.0116
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.1202 0.1566
Mycobacterium ulcerans lipase LipD 0.0037 0.0384 0.0766
Loa Loa (eye worm) hypothetical protein 0.0026 0.0243 0.0317
Brugia malayi MH1 domain containing protein 0.0009 0.0022 0.0043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0243 0.0484
Schistosoma mansoni DNA polymerase eta 0.0019 0.015 0.0195
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0344 0.2118
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0084 0.051
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0384 0.1116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.1202 0.1566
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0026 0.0243 0.0317
Onchocerca volvulus Bile acid receptor homolog 0.003 0.029 0.058
Schistosoma mansoni importin-beta 2 0.0011 0.0047 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3131 0.6263
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.1478 0.911
Schistosoma mansoni nuclear receptor 0.0014 0.0089 0.0116
Brugia malayi MH2 domain containing protein 0.0232 0.2884 0.5756
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0558 0.0727
Entamoeba histolytica HEAT repeat domain containing protein 0.0011 0.0047 0.0052
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Leishmania major cytochrome p450-like protein 0.0016 0.0112 0.0681
Plasmodium falciparum transporter, putative 0.005 0.0553 0.7973
Onchocerca volvulus 0.0396 0.4998 1
Schistosoma mansoni thyroid hormone receptor 0.003 0.029 0.0378
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Echinococcus granulosus importin subunit beta 1 0.0057 0.0636 0.083
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0112 0.0681
Onchocerca volvulus 0.0037 0.0384 0.0768
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0122 0.1478 0.2956
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0384 0.0384
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.4285
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Echinococcus multilocularis SPRY domain containing protein 0.0016 0.0113 0.0113
Giardia lamblia DNA repair protein RAD52 0.0691 0.8786 1
Leishmania major cAMP-specific phosphodiesterase, putative 0.0026 0.0243 0.1492
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0417
Schistosoma mansoni smad 0.0016 0.0112 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0344 0.0687
Schistosoma mansoni hypothetical protein 0.002 0.0167 0.0217
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0094 0.1121 0.2242
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.029 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Loa Loa (eye worm) hypothetical protein 0.0016 0.0113 0.0148
Schistosoma mansoni nuclear receptor 0.0014 0.0089 0.0116
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0044 0.0044
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0384 0.1116
Brugia malayi photoreceptor-specific nuclear receptor 0.0258 0.3227 0.6441
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0222 0.1361
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0026 0.0243 0.0485
Loa Loa (eye worm) Smad1 0.0016 0.0112 0.0146
Leishmania major protein kinase, putative 0.0061 0.0693 0.4268
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0112 0.0146
Brugia malayi Calcitonin receptor-like protein seb-1 0.0397 0.5011 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0122 0.0159
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0026 0.0243 0.1492
Toxoplasma gondii hypothetical protein 0.005 0.0553 0.4285
Echinococcus multilocularis 0.0016 0.0113 0.0113
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0523 0.0682
Echinococcus granulosus tumor protein p63 0.0347 0.4362 0.5687
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.018 0.018
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0211 0.0211
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0026 0.0243 0.0317
Loa Loa (eye worm) hypothetical protein 0.0126 0.1524 0.1986
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.015 0.0915
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0089 0.0116
Brugia malayi steroid hormone receptor 0.003 0.029 0.0579
Brugia malayi conserved hypotetical protein 0.0014 0.0089 0.0177
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0061 0.0693 0.4268
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.1492
Loa Loa (eye worm) oxidoreductase 0.0007 0.0001 0.0001
Loa Loa (eye worm) MBCTL1 0.0057 0.0648 0.0844
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0122 0.0159
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0553 0.0721
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0065 0.0744 0.1485
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.029 0.0579
Loa Loa (eye worm) hypothetical protein 0.0295 0.37 0.4823
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Echinococcus multilocularis dna repair and recombination protein rad54 0.0016 0.0113 0.0113
Toxoplasma gondii hypothetical protein 0.0107 0.1289 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0693 0.0903
Plasmodium vivax DNA repair protein RAD54, putative 0.0016 0.0113 0.162
Loa Loa (eye worm) hypothetical protein 0.0051 0.0561 0.0732
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0112 0.0146
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.266 0.3468
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0089 0.0116
Brugia malayi Importin beta-1 subunit 0.0057 0.0636 0.127
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.1202 0.1202
Brugia malayi nuclear receptor NHR-88 0.003 0.029 0.0579
Mycobacterium tuberculosis Conserved protein 0.0037 0.0384 0.1116
Schistosoma mansoni hypothetical protein 0.0011 0.005 0.0065
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0044 0.0334
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0026 0.0243 0.0243
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.1202 0.2402
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.015 0.0297
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.3497
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0133 0.1622 0.2115
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0016 0.0113 0.0226
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0094 0.1121 0.2242
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.005 0.0553 0.0553
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.029 0.0378
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0553 0.0553
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0061 0.0693 0.4268
Loa Loa (eye worm) hypothetical protein 0.0295 0.37 0.4823
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0636 0.0636
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0384 0.05
Schistosoma mansoni hypothetical protein 0.0126 0.1524 0.1986
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0295 0.37 0.4823
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0133 0.1622 0.3244
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0039 0.041 0.1194
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0089 0.0116
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.1627 0.2121
Schistosoma mansoni hypothetical protein 0.0396 0.4999 0.6517
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0089 0.0177
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0397 0.5011 1
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0133 0.1622 0.1622
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.018 0.0234
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.1202 0.1566
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.015 0.0298
Schistosoma mansoni ran 0.0021 0.018 0.0234
Entamoeba histolytica hypothetical protein 0.0034 0.0344 0.0391
Schistosoma mansoni smad1 5 8 and 0.0016 0.0112 0.0146
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0089 0.0116
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0636 0.4934
Echinococcus granulosus dnaJ subfamily B 0.0396 0.4999 0.6517
Mycobacterium ulcerans hypothetical protein 0.0037 0.0384 0.0766
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.1202 0.2402
Plasmodium falciparum protein serine/threonine kinase-1 0.0061 0.0693 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0026 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0344 0.2118
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0044 0.0058
Onchocerca volvulus 0.005 0.0558 0.1116
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.005 0.0553 0.1103
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0691 0.8786 1
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3131 0.6263
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.018 0.0359
Onchocerca volvulus 0.0037 0.0384 0.0768
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Echinococcus granulosus cpg binding protein 0.0031 0.0311 0.0405
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0222 0.1361
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Brugia malayi ecdysone receptor 0.0014 0.0089 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0243 0.1492
Echinococcus multilocularis transportin 1 0.0011 0.0047 0.0047
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Loa Loa (eye worm) hypothetical protein 0.0037 0.0388 0.0506
Brugia malayi beta-lactamase family protein 0.0037 0.0384 0.0766
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.013 0.0376
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.005 0.0553 0.0721
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0223 0.1369
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0499 0.0996
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.029 0.029
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0558 0.0727
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0396 0.4998 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0002
Trypanosoma cruzi ISWI complex protein 0.0015 0.01 0.0611
Schistosoma mansoni hypothetical protein 0.0271 0.3397 0.4428
Schistosoma mansoni sodium-dependent amino acid transporter 0.005 0.0553 0.0721
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0127 0.0981
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.011 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.029 0.0579
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.0484
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0396 0.4998 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0089 0.0089
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0384 0.05
Leishmania major hypothetical protein, conserved 0.0011 0.0047 0.0282
Plasmodium vivax phosphodiesterase gamma, putative 0.0026 0.0243 0.3497
Mycobacterium ulcerans beta-lactamase 0.0037 0.0384 0.0766
Echinococcus granulosus translational activator gcn1 0.0011 0.0047 0.0061
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0143 0.2048
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0384 0.9352
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.005 0.0553 0.0553
Plasmodium falciparum amino acid transporter, putative 0.005 0.0553 0.7973
Leishmania major hypothetical protein, conserved 0.0037 0.0384 0.2361
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Echinococcus multilocularis SPRY domain containing protein 0.0016 0.0113 0.0113
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0384 0.0766
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0026 0.0243 0.0317
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0064 0.039
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0026 0.0243 0.0317
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0044 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.015 0.0433
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0026 0.0243 0.0317
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Brugia malayi nuclear receptor RXR 0.0016 0.011 0.022
Giardia lamblia Hypothetical protein 0.0026 0.0243 0.0228
Echinococcus multilocularis smad 0.0016 0.0112 0.0112
Brugia malayi tailless protein 0.0014 0.0089 0.0177
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0553 0.0721
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0084 0.0094
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.3497
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0675 0.0675
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0026 0.0243 0.0317
Leishmania major hypothetical protein, conserved 0.0026 0.0243 0.1492
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0061 0.0693 0.5374
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0001 0.0001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0089 0.0089
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0384 0.5532
Echinococcus granulosus dna polymerase kappa 0.0019 0.015 0.0195
Loa Loa (eye worm) hypothetical protein 0.0024 0.0222 0.0289
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0047 0.0355
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0384 0.1116
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0368 0.0479
Brugia malayi Pre-SET motif family protein 0.0214 0.266 0.5308
Brugia malayi MH1 domain containing protein 0.0009 0.0022 0.0043
Trypanosoma brucei ISWI complex protein 0.0015 0.01 0.0611
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0044 0.0621
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0026 0.0243 0.0484
Loa Loa (eye worm) RecQ helicase 0.0025 0.0236 0.0307
Echinococcus granulosus bloom syndrome protein 0.0025 0.0236 0.0307
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0016 0.0113 0.0148
Trichomonas vaginalis hypothetical protein 0.0011 0.0047 0.0092
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0134 0.1627 0.2121
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.1627 0.2121
Echinococcus granulosus SPRY domain containing protein 0.0016 0.0113 0.0147
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.005 0.0065
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0026 0.0243 0.1492
Brugia malayi latrophilin 2 splice variant baaae 0.0271 0.3397 0.6779
Toxoplasma gondii GAF domain-containing protein 0.0039 0.041 0.3179
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0311 0.0405
Loa Loa (eye worm) solute carrier family 6 member 4 0.0295 0.37 0.4823
Schistosoma mansoni coup transcription factor 0.003 0.029 0.0378
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0693 0.0903
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0222 0.0644
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0026 0.0243 0.0317
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.029 0.0378
Trypanosoma brucei unspecified product 0.0013 0.0075 0.0456
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.013 0.0376
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0013 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.1289 0.2576
Echinococcus granulosus dna repair and recombination protein rad54 0.0016 0.0113 0.0148
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.018 0.2581
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0558 0.1116
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0344 0.4962
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0084 0.051
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0384 0.05
Schistosoma mansoni hypothetical protein 0.0126 0.1524 0.1986
Plasmodium falciparum GAF domain-related protein, putative 0.0039 0.041 0.5915
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0397 0.5011 0.6533
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0222 0.0443
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0143 0.0284
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0089 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.029 0.0378
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0384 0.2361
Loa Loa (eye worm) hypothetical protein 0.006 0.0676 0.0881
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0384 0.2361
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.015 0.0915
Plasmodium falciparum phosphodiesterase gamma, putative 0.0026 0.0243 0.3497
Loa Loa (eye worm) hypothetical protein 0.0016 0.011 0.0144
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.029 0.0579
Brugia malayi Bromodomain containing protein 0.0037 0.0387 0.0773
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0558 0.0727
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.1202 0.7404
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0112 0.0681
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0105 0.1256 0.1386
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.005 0.0553 1
Mycobacterium leprae Probable lipase LipE 0.0037 0.0384 0.9352
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.018 0.1102
Brugia malayi MH1 domain containing protein 0.0016 0.0112 0.0224
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0384 0.0766
Brugia malayi MH2 domain containing protein 0.0016 0.0112 0.0224
Echinococcus multilocularis serotonin transporter 0.0295 0.37 0.37
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0243 0.0485
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0024 0.0222 0.0289
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.015 0.0915
Echinococcus granulosus transportin 1 0.0011 0.0047 0.0061
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0561 0.0732
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0026 0.0243 0.1492
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0396 0.4998 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0061 0.0693 0.4268
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0223 0.1369
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0133 0.1622 0.2115
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0026 0.0243 0.3497
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0089 0.0177
Loa Loa (eye worm) PDE1B protein 0.0026 0.0243 0.0317
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0089 0.0116
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0222 0.5393
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0126 0.1524 0.304
Brugia malayi nuclear receptor NHR-67 0.0014 0.0089 0.0177
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0061 0.0693 0.4268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.029 0.0378
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0648 0.1293
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0553 0.0721
Loa Loa (eye worm) hypothetical protein 0.0018 0.0143 0.0186
Echinococcus granulosus SPRY domain containing protein 0.0016 0.0113 0.0147
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0112 0.0221
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0396 0.4998 0.5688
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Echinococcus granulosus importin 5 0.0011 0.0047 0.0061
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.2465 0.3214
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.029 0.0579
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0126 0.1524 0.1524
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.015 0.0169
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0002
Echinococcus multilocularis zinc finger protein 0.0021 0.0174 0.0174
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0089 0.0116
Brugia malayi RNA, U transporter 1 0.0161 0.1977 0.3945
Onchocerca volvulus 0.0051 0.0561 0.1123
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.011 0.0144
Loa Loa (eye worm) hypothetical protein 0.0105 0.1256 0.1637
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.029 0.029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0044 0.0334
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0553 0.0721
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0044 0.0044
Brugia malayi hypothetical protein 0.0024 0.0223 0.0445
Brugia malayi beta-lactamase family protein 0.0037 0.0384 0.0766
Entamoeba histolytica hypothetical protein 0.0197 0.2435 0.2771
Schistosoma mansoni zinc finger protein 0.0021 0.0174 0.0227
Echinococcus multilocularis dual specificity protein kinase clk2 0.0061 0.0693 0.0693
Loa Loa (eye worm) hypothetical protein 0.0018 0.0143 0.0186
Onchocerca volvulus 0.0007 0.0001 0.0002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.1103
Onchocerca volvulus 0.0014 0.0089 0.0178
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0236 0.0236
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.1478 0.911
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.029 0.029
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0009 0.0022 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0243 0.1492
Schistosoma mansoni hypothetical protein 0.0126 0.1524 0.1986
Loa Loa (eye worm) hypothetical protein 0.0271 0.3397 0.4428
Loa Loa (eye worm) hypothetical protein 0.0048 0.0523 0.0682
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.029 0.0579
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.3131 0.6249
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.011 0.0144
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0553 0.0721
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.1289 0.2576
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0417
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.018 0.0234
Loa Loa (eye worm) hypothetical protein 0.003 0.029 0.0378
Mycobacterium tuberculosis Conserved protein 0.0037 0.0384 0.1116
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0358 0.0466
Loa Loa (eye worm) hypothetical protein 0.0018 0.0143 0.0186
Onchocerca volvulus 0.005 0.0553 0.1106
Onchocerca volvulus 0.0014 0.0089 0.0178
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0636 0.3918
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0553 0.0553
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.1627 0.2121
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.029 0.0579
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0026 0.0243 0.1492
Loa Loa (eye worm) DR-78 0.0014 0.0089 0.0116
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.063 0.4888
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3131 0.6263
Entamoeba histolytica hypothetical protein 0.0046 0.0499 0.0567
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.029 0.0378
Leishmania major DNA polymerase eta, putative 0.0019 0.015 0.0915
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.015 0.0195
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.2023 0.4047
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0417
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3131 0.6263
Treponema pallidum sodium- and chloride- dependent transporter 0.0295 0.37 0.5
Onchocerca volvulus 0.005 0.0553 0.1106
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.029 0.0378
Leishmania major GTP-binding protein, putative 0.0021 0.018 0.1102
Entamoeba histolytica DNA repair protein, putative 0.0016 0.0113 0.0128
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Loa Loa (eye worm) hypothetical protein 0.0016 0.011 0.0144
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus multilocularis 0.006 0.0676 0.0676
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0295 0.37 0.7383
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0344 0.4962
Plasmodium vivax amine transporter, putative 0.005 0.0553 0.7973
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.029 0.0579
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0079 0.0922 0.0922
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0028
Leishmania major DNA repair and recombination protein RAD54, putative 0.0016 0.0113 0.0691
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0065 0.0744 0.097
Brugia malayi Pre-SET motif family protein 0.0031 0.0311 0.062
Loa Loa (eye worm) hypothetical protein 0.004 0.0418 0.0544
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0105 0.1256 0.1637
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.029 0.029
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0358 0.0358
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0311 0.0405
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0026 0.0243 0.1492
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.029 0.058
Schistosoma mansoni sodium/chloride dependent transporter 0.0051 0.057 0.0744
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0384 0.05
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0089 0.0178
Brugia malayi hypothetical protein 0.0014 0.0089 0.0177
Brugia malayi hypothetical protein 0.0016 0.0112 0.0223
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0243 0.0484
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0089 0.0177
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.015 0.0195
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Onchocerca volvulus 0.0007 0.0001 0.0002
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0384 0.05
Loa Loa (eye worm) hypothetical protein 0.005 0.0553 0.0721
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0001 0.0001
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0061 0.0693 0.4268
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0311 0.0311
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0001 0.0002
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0039 0.041 0.1194
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0636 0.3918
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0026 0.0243 0.0317
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.4285
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.018 0.1387
Schistosoma mansoni cpg binding protein 0.0031 0.0311 0.0405
Loa Loa (eye worm) serotonin transporter b 0.0295 0.37 0.4823
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0034 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.1202 0.7404
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0016 0.0113 0.0148
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.1202 0.7404
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.013 0.0169
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.029 0.029
Leishmania major DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0744 0.1487
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.1202 0.1202
Toxoplasma gondii hypothetical protein 0.0039 0.041 0.3179
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0558 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0344 0.0687
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.3497
Mycobacterium leprae conserved hypothetical protein 0.0039 0.041 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0744 0.1487
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus multilocularis translational activator gcn1 0.0011 0.0047 0.0047
Schistosoma mansoni cpg binding protein 0.0031 0.0311 0.0405
Toxoplasma gondii hypothetical protein 0.0039 0.041 0.3179
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0112 0.0146
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0344 0.0449
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0167 0.0218
Giardia lamblia DINP protein human, muc B family 0.0019 0.015 0.0121
Schistosoma mansoni hypothetical protein 0.0015 0.01 0.0131
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.1622 1
Trypanosoma brucei protein kinase, putative 0.0101 0.1202 0.7404
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0236 0.047
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0243 0.0485
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0553 0.0721
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.029 0.0378
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0105 0.1256 0.1637
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0222 0.0251
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.015 0.0915
Schistosoma mansoni hypothetical protein 0.0307 0.3852 0.5022
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0013 0.0013
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0089 0.0177
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.011 0.011
Mycobacterium ulcerans hypothetical protein 0.0024 0.0222 0.0442
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0089 0.0116
Brugia malayi hypothetical protein 0.0036 0.0368 0.0734
Schistosoma mansoni Smad4 0.0016 0.0112 0.0146
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0196 0.2819
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0384 0.0766
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0523 0.0682
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0417
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0384 0.1116
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.011 0.0144
Loa Loa (eye worm) hypothetical protein 0.0024 0.0223 0.0291
Onchocerca volvulus 0.0031 0.0311 0.0621
Echinococcus multilocularis importin 5 0.0011 0.0047 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0075 0.0456
Loa Loa (eye worm) hypothetical protein 0.0018 0.0143 0.0186
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Brugia malayi recombination factor GdRad54 0.0016 0.0113 0.0226
Loa Loa (eye worm) latrophilin receptor protein 2 0.0126 0.1524 0.1986
Brugia malayi hypothetical protein 0.005 0.0553 0.1103
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0026 0.0243 0.0484
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0553 0.0721
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.013 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.029 0.0579
Brugia malayi Latrophilin receptor protein 2 0.0126 0.1524 0.304
Echinococcus granulosus zinc finger protein 0.0021 0.0174 0.0227
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0648 0.0648
Schistosoma mansoni bromodomain containing protein 0.0063 0.0719 0.0938
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0222 0.0443
Leishmania major hypothetical protein, conserved 0.0026 0.0243 0.1492
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0105 0.1256 0.1256
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0061 0.0693 0.0903
Loa Loa (eye worm) hypothetical protein 0.0258 0.3227 0.4208
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0034 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0243 0.1492
Schistosoma mansoni hypothetical protein 0.0126 0.1524 0.1986
Loa Loa (eye worm) hypothetical protein 0.0069 0.0792 0.1032
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.1622 0.3244
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0047 0.0355
Schistosoma mansoni hypothetical protein 0.0036 0.0368 0.0479
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0013 0.0016
Brugia malayi kap beta 3 protein 0.0011 0.0047 0.0094
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0344 0.2667
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0222 0.0442
Loa Loa (eye worm) hypothetical protein 0.0016 0.0113 0.0147
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0236 0.047
Leishmania major protein kinase, putative 0.0061 0.0693 0.4268
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.1627 0.1627
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0243 0.1492
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.018 0.2581
Mycobacterium ulcerans putative regulatory protein 0.0039 0.041 0.0819
Echinococcus multilocularis dna repair and recombination protein rad54 0.0016 0.0113 0.0113
Onchocerca volvulus 0.0295 0.37 0.7402
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0089 0.0089
Brugia malayi mbt repeat family protein 0.005 0.0558 0.1113
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Onchocerca volvulus 0.003 0.029 0.058
Loa Loa (eye worm) histone methyltransferase 0.001 0.0034 0.0045
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.4285
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0126 0.1524 0.1986
Schistosoma mansoni cpg binding protein 0.0028 0.0267 0.0348
Onchocerca volvulus 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0243 0.0317
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0222 0.5393
Brugia malayi ecdysteroid receptor 0.003 0.029 0.0579
Loa Loa (eye worm) beta-lactamase 0.0037 0.0384 0.05
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0211 0.0275
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0523 0.0523
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0065 0.0744 0.1485
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0211 0.0275
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0075 0.0456
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0553 0.0721
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0075 0.0456
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0112 0.0112
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.029 0.0378
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.2137 0.4274
Echinococcus granulosus GPCR family 2 0.0126 0.1524 0.1986
Loa Loa (eye worm) hypothetical protein 0.0057 0.0648 0.0844
Echinococcus granulosus Smad4 0.0016 0.0112 0.0146
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0693 0.1385
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.015 0.0297
Loa Loa (eye worm) hypothetical protein 0.0057 0.0636 0.083
Plasmodium falciparum importin beta, putative 0.0057 0.0636 0.9182
Loa Loa (eye worm) hypothetical protein 0.0039 0.041 0.0535
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0222 0.0442
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0079 0.0922 0.1202
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.029 0.0579
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0396 0.4998 0.6516
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.1202 0.7404
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.029 0.0378
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0089 0.0089
Mycobacterium tuberculosis Conserved protein 0.0037 0.0384 0.1116
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.0484
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.1202 0.7404
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0011 0.0047 0.0282
Schistosoma mansoni zinc finger protein 0.0015 0.01 0.0131
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.3497
Brugia malayi hypothetical protein 0.0016 0.011 0.022
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0001 0.0001
Plasmodium falciparum transportin 0.0011 0.0047 0.0661
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.029 0.0378
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0044 0.0058
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.029 0.0579
Schistosoma mansoni importin beta-1 0.0057 0.0636 0.083
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.029 0.0378
Echinococcus granulosus transcription factor btf3 0.0034 0.0344 0.0449
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0236 0.0471
Brugia malayi Smad1 0.0016 0.0112 0.0224
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0016 0.0113 0.0691
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0079 0.0922 0.184
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.1202 0.7404
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.015 0.0195
Loa Loa (eye worm) hypothetical protein 0.0043 0.0462 0.0602
Loa Loa (eye worm) hypothetical protein 0.0014 0.0089 0.0116
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0243 0.1492
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0384 0.0766
Loa Loa (eye worm) hypothetical protein 0.0037 0.0384 0.05
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0089 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.029 0.0579
Brugia malayi CXXC zinc finger family protein 0.0028 0.0267 0.0532
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0396 0.4998 1
Brugia malayi beta-NAC-like protein 0.0034 0.0344 0.0687
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0026 0.0243 0.0317
Brugia malayi MAP kinase sur-1 0.0101 0.1202 0.2398
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0065 0.0744 0.097
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.029 0.058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.029 0.0378
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.018 0.0155
Echinococcus multilocularis dna repair and recombination protein rad54 0.0016 0.0113 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0112 0.0146
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.015 0.0298
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0384 0.1116
Schistosoma mansoni ran 0.0021 0.018 0.0234
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0368 0.0479
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0344 0.0391
Brugia malayi MH2 domain containing protein 0.0016 0.0112 0.0224
Brugia malayi PHD-finger family protein 0.0026 0.0241 0.048
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0648 0.0844
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.1622 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0089 0.0089
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0026 0.0243 0.1492
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Leishmania major importin beta-1 subunit, putative 0.0046 0.0499 0.307
Loa Loa (eye worm) hypothetical protein 0.0397 0.5011 0.6533
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0384 0.0766
Onchocerca volvulus 0.0024 0.0222 0.0444
Leishmania major hypothetical protein, conserved 0.0024 0.0223 0.1369
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.015 0.0915
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.005 0.0553 0.0553
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.1202 0.1324
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0026 0.0243 0.1492
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.2137 0.4274
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0558 0.0727
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0288 0.0376
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0089 0.0116
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.015 0.0915
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.015 0.0297
Schistosoma mansoni zinc finger protein 0.0014 0.0089 0.0116
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0222 0.0644
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0079 0.0922 0.1202
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0065 0.0744 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0243 0.0484
Brugia malayi Steroid receptor seven-up type 2 0.003 0.029 0.0579
Trypanosoma brucei unspecified product 0.0019 0.015 0.0915
Echinococcus multilocularis GPCR, family 2 0.0126 0.1524 0.1524
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.029 0.0579
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.015 0.0915
Loa Loa (eye worm) transcription factor SMAD2 0.0232 0.2884 0.376
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0084 0.051
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.1202 0.2402
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3131 0.6263
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Onchocerca volvulus 0.0244 0.3039 0.608
Brugia malayi Bromodomain containing protein 0.0074 0.0865 0.1727
Onchocerca volvulus 0.0037 0.0384 0.0768
Loa Loa (eye worm) hypothetical protein 0.0016 0.011 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0223 0.1369
Schistosoma mansoni DNA helicase recq1 0.001 0.0044 0.0058
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0122 0.0122
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0126 0.1524 0.1524
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0222 0.0442
Plasmodium vivax hypothetical protein, conserved 0.005 0.0553 0.7973
Brugia malayi Cytochrome P450 family protein 0.0016 0.0112 0.0223
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.029 0.0378
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0089 0.0177
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0553 0.0721
Echinococcus granulosus hypothetical protein 0.006 0.0676 0.0881
Loa Loa (eye worm) norepinephrine transporter 0.0295 0.37 0.4823
Onchocerca volvulus 0.005 0.0553 0.1106
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.3131 0.6263
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0553 0.0721
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0089 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0232 0.2884 0.376
Giardia lamblia Kinase, CMGC CLK 0.0061 0.0693 0.0742
Echinococcus granulosus snurportin 1 0.0604 0.7671 1
Echinococcus granulosus serotonin transporter 0.0295 0.37 0.4823
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0223 0.3207
Schistosoma mansoni smad1 5 8 and 0.0016 0.0112 0.0146
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.005 0.0553 0.0721
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0026 0.0243 0.1879
Echinococcus granulosus FTZ F1 alpha 0.003 0.029 0.0378
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.029 0.0378
Leishmania major hypothetical protein, conserved 0.0015 0.01 0.0611
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0026 0.0243 0.0485
Onchocerca volvulus 0.0028 0.0267 0.0534
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0026 0.0243 0.0317
Plasmodium vivax SET domain protein, putative 0.0031 0.0311 0.4473
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.1627 0.1627
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0222 0.0443
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0084 0.0165
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0344 0.2118
Entamoeba histolytica DNA repair protein, putative 0.0016 0.0113 0.0128
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0499 0.0996
Brugia malayi Protein kinase domain containing protein 0.0061 0.0693 0.1383
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0384 0.0766
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.015 0.0915
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.1622 0.3244
Echinococcus granulosus dual specificity protein kinase clk2 0.0061 0.0693 0.0903
Loa Loa (eye worm) hypothetical protein 0.0037 0.0384 0.05
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0047 0.0061
Schistosoma mansoni thyroid hormone receptor 0.003 0.029 0.0378
Schistosoma mansoni nuclear hormone receptor 0.003 0.029 0.0378
Schistosoma mansoni transcription factor btf3 0.0034 0.0344 0.0449
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.029 0.0378
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0039 0.041 0.0819
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.029 0.0378
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0112 0.0146
Brugia malayi hypothetical protein 0.0016 0.011 0.022
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0223 0.3207
Giardia lamblia hypothetical protein 0.0026 0.0243 0.0228
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0112 0.0146
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.029 0.0378
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0122 0.1478 0.2956
Echinococcus multilocularis cpg binding protein 0.0031 0.0311 0.0311
Mycobacterium ulcerans putative regulatory protein 0.0039 0.041 0.0819
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0396 0.4998 0.9975
Loa Loa (eye worm) hypothetical protein 0.0016 0.011 0.0144
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.2465 0.2465

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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