Detailed information for compound 878167

Basic information

Technical information
  • TDR Targets ID: 878167
  • Name: (E)-N-(5-ethylsulfonyl-2-hydroxyphenyl)-3-phe nylprop-2-enamide
  • MW: 331.386 | Formula: C17H17NO4S
  • H donors: 2 H acceptors: 4 LogP: 2.43 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCS(=O)(=O)c1ccc(c(c1)NC(=O)/C=C/c1ccccc1)O
  • InChi: 1S/C17H17NO4S/c1-2-23(21,22)14-9-10-16(19)15(12-14)18-17(20)11-8-13-6-4-3-5-7-13/h3-12,19H,2H2,1H3,(H,18,20)/b11-8+
  • InChiKey: VZVSNKIMSIIUHC-DHZHZOJOSA-N  


Substructure search Similarity search

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Synonyms

  • N-(5-ethylsulfonyl-2-hydroxyphenyl)-3-phenylprop-2-enamide
  • N-(5-ethylsulfonyl-2-hydroxy-phenyl)-3-phenyl-prop-2-enamide
  • (E)-N-(5-ethylsulfonyl-2-hydroxy-phenyl)-3-phenyl-prop-2-enamide
  • (E)-N-(5-ethylsulfonyl-2-hydroxy-phenyl)-3-phenyl-acrylamide
  • N-(5-ethylsulfonyl-2-hydroxy-phenyl)-3-phenyl-acrylamide
  • ZINC00146144
  • MLS000714439
  • SMR000274418
  • BAS 00570422
  • N-(5-Ethanesulfonyl-2-hydroxy-phenyl)-3-phenyl-acrylamide
  • ST5183208

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni patched 1 0.0051 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0031 0.0053
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0197 0.0713 0.1366
Echinococcus multilocularis glutamate receptor 2 0.0058 0.0159 0.0159
Trypanosoma brucei ISWI complex protein 0.0038 0.0079 0.0861
Loa Loa (eye worm) hypothetical protein 0.0066 0.0189 0.0363
Schistosoma mansoni rab6-interacting 0.0052 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0047 0.0113 0.0217
Echinococcus granulosus lipoxygenase domain containing protein 0.0052 0.0134 0.0134
Brugia malayi MH2 domain containing protein 0.0021 0.0008 0.0015
Brugia malayi jmjC domain containing protein 0.0047 0.0113 0.0217
Leishmania major Pyridoxal kinase, putative 0.0026 0.003 0.0292
Echinococcus multilocularis receptor type guanylyl cyclase 0.0058 0.0159 0.0159
Schistosoma mansoni hypothetical protein 0.0066 0.0189 0.0189
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.003 0.0046 0.0482
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0033 0.0058 0.0621
Echinococcus granulosus receptor type guanylyl cyclase 0.0058 0.0159 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0037 0.0071
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0008 0.004
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0047 0.0113 0.1649
Schistosoma mansoni phosphatidylserine receptor 0.0047 0.0113 0.0113
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0107 0.0353 0.4033
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0033 0.0058 0.0621
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0163 0.0312
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0026 0.0043
Echinococcus granulosus calpain A 0.0055 0.0145 0.0145
Schistosoma mansoni cpg binding protein 0.0035 0.0064 0.0064
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0201 0.0338
Loa Loa (eye worm) hypothetical protein 0.0058 0.0158 0.0303
Entamoeba histolytica hypothetical protein, conserved 0.0037 0.0075 0.1866
Loa Loa (eye worm) hypothetical protein 0.0096 0.031 0.0595
Echinococcus granulosus cpg binding protein 0.0035 0.0064 0.0064
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0026 0.0031 0.0031
Echinococcus multilocularis musashi 0.0059 0.0163 0.0163
Schistosoma mansoni hypothetical protein 0.0049 0.0122 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0096 0.0184
Trypanosoma cruzi pyridoxal kinase, putative 0.0026 0.003 0.0292
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0037 0.0037
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0112 0.0375 0.4287
Brugia malayi Heterochromatin protein 1 0.0114 0.0382 0.0733
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0037 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0068
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0058 0.0159 0.0305
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0021
Schistosoma mansoni smad 0.0021 0.0008 0.0008
Trypanosoma brucei PAB1-binding protein , putative 0.004 0.0087 0.0959
Trichomonas vaginalis ap endonuclease, putative 0.003 0.0046 0.0077
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0037 0.0037
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0088 0.0148
Loa Loa (eye worm) glutaminase 2 0.0825 0.323 0.6193
Schistosoma mansoni hypothetical protein 0.0066 0.0189 0.0189
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.003 0.0046 0.0046
Mycobacterium ulcerans hypothetical protein 0.0124 0.0423 0.1287
Plasmodium falciparum ataxin-2 like protein, putative 0.004 0.0087 0.4394
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.004 0.01
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0052 0.01
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0114 0.0381 0.0381
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0023 0.0019 0.0117
Schistosoma mansoni hypothetical protein 0.0114 0.0381 0.0381
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1685 0.6676 0.6676
Mycobacterium ulcerans lipase LipD 0.0023 0.0019 0.0035
Schistosoma mansoni loxhd1 0.0052 0.0134 0.0134
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.0019 0.0019
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0026 0.0031 0.0313
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0019 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0012 0.002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0037 0.0037
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0053 0.0139 0.0139
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0189 0.0189
Echinococcus multilocularis calpain family protein 1, d 0.0037 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0208 0.076 0.1457
Echinococcus multilocularis geminin 0.052 0.2008 0.2008
Loa Loa (eye worm) hypothetical protein 0.0317 0.1196 0.2293
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0019 0.0032
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0037 0.0062
Plasmodium vivax SET domain protein, putative 0.019 0.0686 1
Schistosoma mansoni tyrosine kinase 0.0058 0.0159 0.0159
Brugia malayi Cytochrome P450 family protein 0.0021 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0037 0.0037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Mycobacterium ulcerans hypothetical protein 0.0029 0.004 0.01
Brugia malayi hypothetical protein 0.0052 0.0134 0.0258
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0219 0.0655
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.051 0.5843
Schistosoma mansoni glutamate receptor AMPA 0.0114 0.0381 0.0381
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.004 0.0994
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0112 0.0372 0.4251
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0076
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0088 0.1284
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0037 0.0062
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0189 0.0684 0.0684
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Brugia malayi jmjC domain containing protein 0.0047 0.0113 0.0217
Schistosoma mansoni protein phosphatase 2C 0.0047 0.0113 0.0113
Schistosoma mansoni rab6-interacting 0.0052 0.0134 0.0134
Trichomonas vaginalis chaperonin, putative 0.002 0.0004 0.0007
Loa Loa (eye worm) PHD-finger family protein 0.0068 0.0199 0.0381
Plasmodium falciparum histone acetyltransferase GCN5 0.0032 0.0053 0.2659
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.003 0.0046 0.2316
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0037 0.0071
Loa Loa (eye worm) acetyltransferase 0.0124 0.0422 0.0809
Onchocerca volvulus 0.0058 0.0159 0.0267
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0031 0.0053
Plasmodium vivax JmjC domain containing protein 0.0047 0.0113 0.1649
Loa Loa (eye worm) transcription factor SMAD2 0.0302 0.1136 0.2178
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0098 0.028
Echinococcus multilocularis JmjC domain containing protein 4 0.0047 0.0113 0.0113
Echinococcus multilocularis lamin dm0 0.0059 0.0163 0.0163
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0208 0.076 0.1457
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0219 0.0219
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.0026 0.0049
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0047 0.0113 0.1259
Brugia malayi SET domain containing protein 0.0026 0.003 0.0058
Schistosoma mansoni glutamate receptor NMDA 0.0114 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0141 0.0492 0.0943
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0037 0.0037
Echinococcus multilocularis muscleblind protein 0.018 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0051 0.013 0.0248
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Loa Loa (eye worm) hypothetical protein 0.0064 0.0181 0.0348
Mycobacterium ulcerans beta-lactamase 0.0023 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.005 0.0126 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0037 0.0071
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0606 0.0606
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0026 0.0031 0.0031
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.013 0.013
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0112 0.0375 0.4287
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0172 0.0615 0.0615
Loa Loa (eye worm) hypothetical protein 0.0062 0.0176 0.0337
Loa Loa (eye worm) hypothetical protein 0.0119 0.0401 0.077
Loa Loa (eye worm) hypothetical protein 0.0141 0.0492 0.0943
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0043 0.0098 0.0098
Echinococcus granulosus TGF beta signal transducer SmadC 0.0021 0.0008 0.0008
Brugia malayi acetyltransferase, GNAT family protein 0.0124 0.0422 0.0809
Echinococcus granulosus chromobox protein 1 0.0114 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0021
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0043 0.0098 0.0098
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0146 0.1643
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0058 0.0159 0.0305
Trypanosoma cruzi pyridoxal kinase, putative 0.0026 0.003 0.0292
Brugia malayi jmjC domain containing protein 0.0047 0.0113 0.0217
Echinococcus granulosus jumonji domain containing protein 0.0095 0.0306 0.0306
Schistosoma mansoni cellular tumor antigen P53 0.0114 0.038 0.038
Plasmodium vivax multidomain scavenger receptor, putative 0.0052 0.0134 0.1959
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0028 0.0036 0.053
Brugia malayi Metabotropic glutamate receptor precursor. 0.0058 0.0159 0.0305
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0043 0.0098 0.1084
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0058 0.0158 0.0158
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0154 0.0543 0.0543
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0011 0.0159
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0163 0.0312
Echinococcus granulosus atrial natriuretic peptide receptor 0.0058 0.0159 0.0159
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.004 0.0087 0.0957
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0033 0.0058 0.0621
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0058 0.0159 0.0159
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0055 0.0146 1
Brugia malayi RNA binding protein 0.0248 0.0919 0.1761
Trypanosoma cruzi tyrosine phosphatase, putative 0.0037 0.0075 0.0817
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0019 0.0032
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0037 0.0071
Echinococcus multilocularis peregrin 0.0077 0.0234 0.0234
Echinococcus multilocularis lysine specific demethylase 5A 0.0176 0.063 0.063
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0107 0.0353 0.0677
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.021 0.0767 0.0767
Echinococcus multilocularis nmda type glutamate receptor 0.1112 0.4381 0.4381
Loa Loa (eye worm) calpain family protein 1 0.0052 0.0134 0.0257
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0189 0.0684 0.0684
Onchocerca volvulus 0.0037 0.0072 0.0121
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0317 0.1196 0.2293
Brugia malayi AMP-binding enzyme family protein 0.0029 0.004 0.0076
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0011 0.0549
Echinococcus granulosus transcription factor Dp 1 0.0062 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.052 0.201 0.3854
Echinococcus granulosus fetal alzheimer antigen falz 0.0058 0.0158 0.0158
Mycobacterium tuberculosis Conserved protein 0.0023 0.0019 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0019 0.0276
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0112 0.0375 0.5467
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0043 0.0098 0.0844
Onchocerca volvulus 0.0019 0.000000031774 0.000000053428
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.0159 0.0305
Echinococcus multilocularis zinc finger protein 0.0054 0.014 0.014
Entamoeba histolytica exodeoxyribonuclease III, putative 0.003 0.0046 0.1145
Echinococcus granulosus lamin dm0 0.0059 0.0163 0.0163
Loa Loa (eye worm) jmjC domain-containing protein 0.0141 0.049 0.0938
Mycobacterium tuberculosis Probable hydrolase 0.0023 0.0019 0.0117
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.004 0.01
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.002 0.0004 0.0106
Brugia malayi calpain family protein 1 0.0052 0.0134 0.0257
Trypanosoma cruzi ISWI complex protein 0.0038 0.0079 0.0861
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0021
Onchocerca volvulus 0.0058 0.0159 0.0267
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.003 0.0046 0.0365
Leishmania major hypothetical protein, conserved 0.0047 0.0113 0.1259
Echinococcus granulosus acyl protein thioesterase 12 0.0044 0.0102 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0021 0.0312
Loa Loa (eye worm) doublecortin family protein 0.0052 0.0134 0.0258
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.1534 0.1534
Onchocerca volvulus 0.0029 0.004 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0037 0.0037
Schistosoma mansoni coup transcription factor 0.0028 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0099 0.0324 0.8059
Echinococcus multilocularis ubiquitin specific protease 41 0.0026 0.0031 0.0031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0037 0.0062
Echinococcus granulosus GPCR family 2 0.0066 0.0189 0.0189
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.009 0.0286 0.0286
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0037 0.0071
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0037 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0114 0.038 0.0729
Onchocerca volvulus 0.0055 0.0144 0.0242
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.013 0.0248
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Schistosoma mansoni hypothetical protein 0.0106 0.035 0.035
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0008 0.0015
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0076
Brugia malayi Smad1 0.0021 0.0008 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0008 0.0015
Schistosoma mansoni lipoxygenase 0.0189 0.0684 0.0684
Leishmania major hypothetical protein, conserved 0.0023 0.0019 0.017
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0038 0.0079 0.0079
Onchocerca volvulus 0.0023 0.0019 0.0032
Toxoplasma gondii PHD-finger domain-containing protein 0.0068 0.0199 0.2893
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0146 0.1643
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0026 0.0043
Brugia malayi nuclear hormone receptor 0.0028 0.0037 0.0071
Loa Loa (eye worm) MH2 domain-containing protein 0.0302 0.1136 0.2178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0219 0.0655
Brugia malayi hypothetical protein 0.0099 0.0324 0.062
Schistosoma mansoni hypothetical protein 0.0049 0.0122 0.0122
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0195 0.0707 0.0707
Schistosoma mansoni tar DNA-binding protein 0.0248 0.0919 0.0919
Onchocerca volvulus Huntingtin homolog 0.0197 0.0713 0.1198
Brugia malayi jmjC domain containing protein 0.0317 0.1195 0.229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0236 0.0869 1
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0028 0.0036 0.1832
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.004 0.004
Toxoplasma gondii Erv1 / Alr family protein 0.0028 0.0036 0.053
Entamoeba histolytica hypothetical protein 0.0099 0.0324 0.8059
Echinococcus granulosus chromobox protein 1 0.0114 0.0382 0.0382
Brugia malayi hypothetical protein 0.0317 0.1196 0.2293
Echinococcus granulosus smad 0.0021 0.0008 0.0008
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0037 0.0037
Mycobacterium tuberculosis Probable lipase LipD 0.0023 0.0019 0.0117
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0219 0.1955
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.009 0.0286 0.0286
Plasmodium falciparum ataxin-2 like protein, putative 0.004 0.0087 0.4394
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Plasmodium falciparum pyridoxal kinase 0.0026 0.003 0.1488
Echinococcus multilocularis Protein lozenge 0.004 0.0085 0.0085
Trypanosoma cruzi lysophospholipase, putative 0.0044 0.0102 0.1126
Brugia malayi TAR-binding protein 0.0248 0.0919 0.1761
Onchocerca volvulus Alhambra homolog 0.0068 0.0199 0.0334
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0058 0.0159 0.0267
Schistosoma mansoni hypothetical protein 0.0049 0.0122 0.0122
Toxoplasma gondii hypothetical protein 0.0038 0.0077 0.1129
Loa Loa (eye worm) hypothetical protein 0.018 0.0648 0.1242
Schistosoma mansoni inositol monophosphatase 0.0055 0.0146 0.0146
Onchocerca volvulus 0.0023 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0036
Echinococcus granulosus dnaJ subfamily B 0.0402 0.1534 0.1534
Echinococcus granulosus glutamate receptor NMDA 0.1054 0.4148 0.4148
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0113 0.0217
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.003 0.0046 0.0119
Trichomonas vaginalis esterase, putative 0.0023 0.0019 0.0032
Echinococcus multilocularis acyl protein thioesterase 1 0.0044 0.0102 0.0102
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.019 0.0686 1
Schistosoma mansoni polycystin 1-related 0.0052 0.0134 0.0134
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0037 0.0071
Echinococcus granulosus metabotropic glutamate receptor 2 0.0058 0.0159 0.0159
Schistosoma mansoni lipoxygenase 0.0095 0.0307 0.0307
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0172 0.0615 0.0615
Loa Loa (eye worm) hypothetical protein 0.0177 0.0635 0.1218
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0037 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0375 0.0631
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0037 0.0037
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0145 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0037 0.0071
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0112 0.0375 0.4287
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0112 0.0372 0.4251
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0037 0.0072 0.0138
Echinococcus granulosus peregrin 0.0077 0.0234 0.0234
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0124 0.0422 0.0422
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0208 0.076 0.1457
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0008 0.0015
Schistosoma mansoni lamin 0.0059 0.0163 0.0163
Schistosoma mansoni hypothetical protein 0.0099 0.0324 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0037 0.0071
Schistosoma mansoni bromodomain containing protein 0.0163 0.0579 0.0579
Loa Loa (eye worm) hypothetical protein 0.0047 0.0113 0.0217
Echinococcus granulosus inositol monophosphatase 1 0.0055 0.0146 0.0146
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0142 0.0494 0.0946
Brugia malayi MH2 domain containing protein 0.0021 0.0008 0.0015
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0107 0.0353 0.8797
Loa Loa (eye worm) hypothetical protein 0.004 0.0087 0.0167
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0037 0.0071
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0107 0.0353 0.0677
Echinococcus multilocularis smad 0.0021 0.0008 0.0008
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0028 0.0036 0.0371
Onchocerca volvulus 0.0028 0.0038 0.0064
Onchocerca volvulus 0.0052 0.0134 0.0226
Echinococcus granulosus histone acetyltransferase KAT2B 0.0115 0.0385 0.0385
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.002 0.0004 0.0004
Echinococcus multilocularis microtubule associated protein 2 0.2515 1 1
Echinococcus multilocularis expressed conserved protein 0.0112 0.0373 0.0373
Echinococcus granulosus Chromobox protein 3 0.0019 0.000000031774 0.000000031774
Trichomonas vaginalis ap endonuclease, putative 0.003 0.0046 0.0077
Loa Loa (eye worm) hypothetical protein 0.0068 0.0199 0.0381
Giardia lamblia Histone acetyltransferase GCN5 0.0032 0.0053 0.1309
Schistosoma mansoni microtubule-associated protein tau 0.2515 1 1
Schistosoma mansoni lamin 0.0059 0.0163 0.0163
Wolbachia endosymbiont of Brugia malayi esterase 0.0044 0.0102 0.5548
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0019 0.0019
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0023 0.0019 0.0117
Echinococcus multilocularis mitogen activated protein kinase 0.0112 0.0375 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0014 0.0023
Echinococcus granulosus survival motor neuron protein 1 0.052 0.201 0.201
Echinococcus granulosus lamin 0.0059 0.0163 0.0163
Brugia malayi jmjC domain containing protein 0.0047 0.0113 0.0217
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0037 0.0071
Toxoplasma gondii exonuclease III APE 0.003 0.0046 0.067
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0107 0.0179
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0172 0.0615 0.0615
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0037 0.0037
Echinococcus multilocularis cpg binding protein 0.0035 0.0064 0.0064
Leishmania major hypothetical protein, conserved 0.0146 0.051 0.5843
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Onchocerca volvulus 0.0028 0.0037 0.0062
Schistosoma mansoni glutaminase 0.0825 0.323 0.323
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.019 0.0686 0.0686
Loa Loa (eye worm) glutamate receptor 1 0.0114 0.0381 0.0731
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0112 0.0375 0.4287
Schistosoma mansoni smad1 5 8 and 0.0021 0.0008 0.0008
Brugia malayi AF-10 protein 0.0022 0.0015 0.0028
Brugia malayi T-complex protein 1, beta subunit 0.002 0.0004 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0219 0.0655
Brugia malayi Pre-SET motif family protein 0.019 0.0686 0.1316
Leishmania major lysophospholipase, putative 0.0044 0.0102 0.1126
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0068 0.0199 0.0199
Brugia malayi calpain family protein 1 0.0052 0.0134 0.0257
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0375 0.0631
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0058 0.0159 0.0159
Entamoeba histolytica hypothetical protein 0.0099 0.0324 0.8059
Loa Loa (eye worm) heterochromatin protein 1 0.0114 0.0382 0.0733
Trichomonas vaginalis phosphomethylpyrimidine kinase, putative 0.0026 0.003 0.005
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0015 0.0119
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0409 0.0409
Echinococcus multilocularis PHD finger protein rhinoceros 0.0068 0.0199 0.0199
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.013 0.013
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0088 0.0148
Echinococcus multilocularis tumor protein p63 0.0776 0.3034 0.3034
Echinococcus granulosus ubiquitin specific protease 41 0.0026 0.0031 0.0031
Echinococcus multilocularis neuropeptide receptor A26 0.0327 0.1236 0.1236
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0219 0.3191
Echinococcus granulosus acyl protein thioesterase 1 0.0044 0.0102 0.0102
Schistosoma mansoni zinc finger protein 0.0038 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0112 0.0372 0.4251
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0113 0.0217
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.002 0.0004 0.0004
Echinococcus granulosus pyridoxal kinase 0.0026 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0036
Loa Loa (eye worm) jmjC domain-containing protein 0.0182 0.0656 0.1257
Brugia malayi nuclear receptor NHR-88 0.0028 0.0037 0.0071
Echinococcus multilocularis jumonji domain containing 1A 0.0047 0.0113 0.0113
Onchocerca volvulus Transmembrane 9 superfamily member 4 homolog 0.0028 0.0036 0.006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0099 0.0324 0.0324
Echinococcus granulosus PHD finger protein rhinoceros 0.0068 0.0199 0.0199
Schistosoma mansoni eyes absent homolog 0.0141 0.0492 0.0492
Schistosoma mansoni lozenge 0.004 0.0085 0.0085
Echinococcus granulosus JmjC domain containing protein 4 0.0047 0.0113 0.0113
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0146 0.1643
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0031 0.0313
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0098 0.028
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1321 0.5216 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0032 0.0053 0.1315
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0037 0.0037
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0037 0.0037
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0189 0.0363
Brugia malayi intermediate filament protein 0.0059 0.0163 0.0312
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase) (PTPase) 0.013 0.0446 0.4038
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.003 0.0046 0.067
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0107 0.0353 0.0353
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.0159 0.0305
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.004 0.0309
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0401 0.0401
Echinococcus granulosus intermediate filament protein 0.0059 0.0163 0.0163
Schistosoma mansoni glutamate receptor kainate 0.0114 0.0381 0.0381
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0112 0.0375 0.4287
Brugia malayi Augmenter of liver regeneration 0.0028 0.0036 0.007
Onchocerca volvulus 0.0114 0.038 0.0639
Brugia malayi AMP-binding enzyme family protein 0.0029 0.004 0.0076
Brugia malayi Protein-tyrosine phosphatase 0.0059 0.016 0.0307
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.017
Schistosoma mansoni jumonji/arid domain-containing protein 0.0182 0.0656 0.0656
Brugia malayi PHD-finger family protein 0.0068 0.0199 0.0381
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.004 0.01
Brugia malayi MH1 domain containing protein 0.0021 0.0008 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0037 0.0071
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0019 0.0032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0248 0.0919 0.1761
Trypanosoma cruzi extracellular receptor, putative 0.0058 0.0159 0.1789
Mycobacterium tuberculosis Possible penicillin-binding protein 0.015 0.0524 0.4761
Mycobacterium tuberculosis Probable lipase LipE 0.0023 0.0019 0.0117
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0172 0.0615 0.0615
Trypanosoma brucei protein kinase, putative 0.0112 0.0375 0.4287
Echinococcus multilocularis nmda type glutamate receptor 0.146 0.5773 0.5773
Toxoplasma gondii LsmAD domain-containing protein 0.004 0.0087 0.1271
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0055 0.0146 0.3646
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0026 0.0031 0.0031
Brugia malayi hypothetical protein 0.052 0.201 0.3854
Brugia malayi AMP-binding enzyme family protein 0.0029 0.004 0.0076
Schistosoma mansoni hypothetical protein 0.0142 0.0496 0.0496
Echinococcus granulosus lipoxygenase domain containing protein 0.0052 0.0134 0.0134
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0163 0.0312
Leishmania major hypothetical protein, conserved 0.0038 0.0079 0.0861
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.004 0.0994
Brugia malayi exodeoxyribonuclease III family protein 0.003 0.0046 0.0088
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.004 0.0412
Echinococcus multilocularis transcription factor Dp 1 0.0062 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0076
Leishmania major extracellular receptor, putative 0.0058 0.0159 0.1789
Echinococcus granulosus histone lysine methyltransferase setb 0.0233 0.0857 0.0857
Echinococcus multilocularis tyrosine kinase 0.0058 0.0159 0.0159
Giardia lamblia PHD finger protein 15 0.0068 0.0199 0.5237
Echinococcus granulosus nmda type glutamate receptor 0.146 0.5773 0.5773
Schistosoma mansoni tar DNA-binding protein 0.0248 0.0919 0.0919
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0113 0.0217
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0099 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0111 0.0371 0.0712
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0076
Mycobacterium tuberculosis Probable esterase LipL 0.0023 0.0019 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0037 0.0071
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0107 0.0353 0.0353
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0055 0.0146 0.0246
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0292 0.1095 1
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0037 0.0037
Loa Loa (eye worm) glutamate receptor 0.0058 0.0159 0.0305
Echinococcus multilocularis lipoxygenase domain containing protein 0.0052 0.0134 0.0134
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0037 0.0037
Loa Loa (eye worm) Smad1 0.0021 0.0008 0.0015
Brugia malayi CHD4 protein 0.0025 0.0026 0.0049
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0172 0.0615 0.0615
Schistosoma mansoni hypothetical protein 0.0022 0.0015 0.0015
Leishmania major cytochrome p450-like protein 0.0021 0.0008 0.004
Echinococcus granulosus glutamate receptor subunit protein glur 0.0114 0.0381 0.0381
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.0019 0.0036
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpB 0.013 0.0446 0.1359
Mycobacterium ulcerans esterase/lipase LipP 0.0023 0.0019 0.0035
Brugia malayi Cytochrome P450 family protein 0.0021 0.0008 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0037 0.0071
Trichomonas vaginalis inositol monophosphatase, putative 0.0055 0.0146 0.0246
Loa Loa (eye worm) glutamate receptor 2 0.0114 0.0381 0.0731
Loa Loa (eye worm) hypothetical protein 0.0051 0.0131 0.025
Echinococcus granulosus muscleblind protein 0.018 0.0648 0.0648
Echinococcus granulosus geminin 0.052 0.2008 0.2008
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0036 0.0363
Schistosoma mansoni metabotropic glutamate receptor 0.0058 0.0159 0.0159
Schistosoma mansoni hypothetical protein 0.0402 0.1534 0.1534
Echinococcus multilocularis Chromobox protein 3 0.0019 0.000000031774 0.000000031774
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0107 0.0353 0.4033
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.002 0.0004 0.0062
Loa Loa (eye worm) hepatopoietin HPO2 0.0028 0.0036 0.007
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0021 0.0008 0.0008
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0055 0.0145 0.0145
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0052 0.0134 0.0134
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.021 0.0767 0.0767
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0236 0.0869 1
Brugia malayi steroid hormone receptor 0.0028 0.0037 0.0071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0021
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0406 0.1551 0.1551
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.0019 0.0019
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0028 0.0036 0.0371
Schistosoma mansoni tar DNA-binding protein 0.0248 0.0919 0.0919
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0024 0.0021 0.1079
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0008 0.004
Plasmodium falciparum phd finger protein, putative 0.0068 0.0199 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.004 0.0412
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.017
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0055 0.0146 0.2133
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0257
Echinococcus multilocularis pyridoxal kinase 0.0026 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0037 0.0071
Schistosoma mansoni ap endonuclease 0.003 0.0046 0.0046
Chlamydia trachomatis glutamine binding protein 0.0292 0.1095 1
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0114 0.0381 0.0381
Echinococcus multilocularis muscleblind protein 1 0.018 0.0648 0.0648
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.004 0.01
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0112 0.0375 0.0719
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0019 0.0019
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0113 0.0113
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0058 0.0159 0.0159
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.0159 0.0305
Schistosoma mansoni survival motor neuron protein 0.0106 0.035 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.013 0.0218
Brugia malayi PHD-finger family protein 0.0029 0.004 0.0077
Echinococcus granulosus jumonji domain containing 1A 0.0047 0.0113 0.0113
Echinococcus granulosus glutamate receptor 2 0.0058 0.0159 0.0159
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0172 0.0615 0.0615
Schistosoma mansoni transcription factor LCR-F1 0.0099 0.0324 0.0324
Schistosoma mansoni zinc finger protein 0.0054 0.014 0.014
Trichomonas vaginalis set domain proteins, putative 0.1503 0.5947 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0088 0.0088
Leishmania major hypothetical protein, unknown function 0.0037 0.0075 0.0817
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0015 0.0119
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0181 0.0305
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0037 0.0037
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0022 0.0015 0.0212
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0182 0.0656 0.0656
Schistosoma mansoni glutamate receptor kainate 0.0114 0.0381 0.0381
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0219 0.0219
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0037 0.0037
Echinococcus granulosus neuropeptide receptor A26 0.0327 0.1236 0.1236
Schistosoma mansoni hypothetical protein 0.0052 0.0134 0.0134
Brugia malayi chromobox protein homolog 3 0.0064 0.0181 0.0348
Loa Loa (eye worm) glutaminase 0.0825 0.323 0.6193
Trichomonas vaginalis glutaminase, putative 0.0825 0.323 0.5432
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0026 0.0043
Echinococcus multilocularis mothers against decapentaplegic 5 0.0021 0.0008 0.0008
Brugia malayi Muscleblind-like protein 0.018 0.0648 0.1242
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0375 0.0631
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0037 0.0071
Echinococcus multilocularis RUN 0.0052 0.0134 0.0134
Echinococcus granulosus glutamate NMDA receptor subunit 0.0114 0.0381 0.0381
Echinococcus multilocularis survival motor neuron protein 1 0.052 0.201 0.201
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.004 0.0994
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0026 0.0043
Brugia malayi Bromodomain containing protein 0.0099 0.0321 0.0616
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.021 0.0767 0.0767
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.002 0.0004 0.0004
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0258
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0401 0.0401
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.0096 0.0096
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0026 0.0026
Echinococcus granulosus Polycystic kidney disease protein 0.0052 0.0134 0.0134
Leishmania major phosphoinositide phosphatase 0.013 0.0446 0.5103
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0049 0.0123 0.1075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.006
Echinococcus multilocularis GPCR, family 2 0.0066 0.0189 0.0189
Echinococcus multilocularis neuropeptide s receptor 0.0327 0.1236 0.1236
Trypanosoma cruzi PAB1-binding protein , putative 0.004 0.0087 0.0959
Brugia malayi Bromodomain containing protein 0.0077 0.0234 0.0448
Schistosoma mansoni tar DNA-binding protein 0.0248 0.0919 0.0919
Brugia malayi CHE-14 protein 0.0051 0.013 0.0248
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0114 0.0381 0.0381
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.021 0.0767 0.0767
Schistosoma mansoni cpg binding protein 0.0028 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Echinococcus granulosus phd:f box containing protein 0.0047 0.0113 0.0113
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0189 0.0363
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0064 0.0181 0.0305
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0015 0.0212
Schistosoma mansoni protein kinase 0.0058 0.0159 0.0159
Trypanosoma cruzi PAB1-binding protein , putative 0.004 0.0087 0.0959
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0113 0.1259
Echinococcus multilocularis lipoxygenase domain containing protein 0.0052 0.0134 0.0134
Echinococcus granulosus RUN 0.0052 0.0134 0.0134
Trichomonas vaginalis chromobox protein, putative 0.0114 0.0382 0.0643
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0026 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.0058 0.0159 0.3962
Echinococcus multilocularis glutamate receptor NMDA 0.1054 0.4148 0.4148
Echinococcus multilocularis thyroid hormone receptor alpha 0.0223 0.0819 0.0819
Trichomonas vaginalis pyridoxine kinase, putative 0.0026 0.003 0.005
Brugia malayi jmjC domain containing protein 0.0182 0.0656 0.1257
Trypanosoma brucei pyridoxal kinase 0.0026 0.003 0.0292
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0036
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0026 0.0031 0.0031
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0201 0.0338
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0019 0.017
Echinococcus granulosus lysine specific demethylase 5A 0.0182 0.0656 0.0656
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0037 0.0037
Plasmodium vivax pyridoxal kinase, putative 0.0026 0.003 0.043
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0114 0.0381 0.0381
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0047 0.0113 0.1649
Mycobacterium tuberculosis Conserved protein 0.0023 0.0019 0.0117
Loa Loa (eye worm) hypothetical protein 0.0142 0.0496 0.0951
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0038 0.0073
Brugia malayi CXXC zinc finger family protein 0.0028 0.0038 0.0073
Brugia malayi Receptor family ligand binding region containing protein 0.0058 0.0159 0.0305
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0052 0.01
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.021 0.0767 0.0767
Schistosoma mansoni smad1 5 8 and 0.0021 0.0008 0.0008
Schistosoma mansoni glutamate receptor kainate 0.0114 0.0381 0.0381
Echinococcus multilocularis calpain A 0.0055 0.0145 0.0145
Plasmodium vivax ataxin-2 like protein, putative 0.004 0.0087 0.1271
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0037 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0037 0.0071
Schistosoma mansoni hypothetical protein 0.052 0.2008 0.2008
Echinococcus multilocularis protein dispatched 1 0.0058 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0055 0.0147 0.0282
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0292 0.1095 0.3373
Schistosoma mansoni cpg binding protein 0.0035 0.0064 0.0064
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0055 0.0146 0.0246
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0193 0.0193
Schistosoma mansoni inositol monophosphatase 0.0055 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Plasmodium falciparum LCCL domain-containing protein 0.0052 0.0134 0.6773
Echinococcus granulosus mothers against decapentaplegic 5 0.0021 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0099 0.0324 0.8059
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Brugia malayi hypothetical protein 0.0141 0.0492 0.0943
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0058 0.0158 0.0158
Entamoeba histolytica pyridoxal kinase, putative 0.0026 0.003 0.0736
Onchocerca volvulus 0.1503 0.5947 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0037 0.0037
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.004 0.0412
Schistosoma mansoni intermediate filament proteins 0.0059 0.0163 0.0163
Schistosoma mansoni acyl-protein thioesterase 12 (lysophospholipase III) 0.0044 0.0102 0.0102
Trichomonas vaginalis phosphomethylpyrimidine kinase, putative 0.0026 0.003 0.005
Echinococcus multilocularis inositol monophosphatase 1 0.0055 0.0146 0.0146
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0195 0.0707 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0181 0.0305
Loa Loa (eye worm) phospholipase/Carboxylesterase 0.0044 0.0102 0.0195
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0031 0.0313
Trypanosoma brucei lysophospholipase, putative 0.0044 0.0102 0.1126
Loa Loa (eye worm) hypothetical protein 0.0105 0.0346 0.0663
Schistosoma mansoni Smad4 0.0021 0.0008 0.0008
Brugia malayi hypothetical protein 0.0058 0.0159 0.0305
Schistosoma mansoni chromobox protein 0.0114 0.0382 0.0382
Toxoplasma gondii t-complex protein beta subunit 0.002 0.0004 0.0062
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.0096 0.0096
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.002 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0077
Mycobacterium ulcerans hypothetical protein 0.0023 0.0019 0.0035
Schistosoma mansoni phd/f-box containing protein 0.0047 0.0113 0.0113
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0023 0.0019 0.0117
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.019 0.0686 0.0686
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0189 0.0189
Brugia malayi Guanylyl cyclase protein 23 0.0058 0.0159 0.0305
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0114 0.0381 0.0381
Brugia malayi Inositol-1 0.0055 0.0146 0.0281
Leishmania major mitochondrial DNA polymerase beta 0.0236 0.0869 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0028 0.0036 0.0371
Echinococcus granulosus zinc finger protein 0.0054 0.014 0.014
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0606 0.0606
Onchocerca volvulus 0.0317 0.1196 0.2011
Leishmania major hypothetical protein, conserved 0.0028 0.0036 0.0371
Echinococcus multilocularis lamin 0.0059 0.0163 0.0163
Leishmania major hypothetical protein, conserved 0.004 0.0087 0.0959
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0014 0.0023
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0189 0.0189
Echinococcus multilocularis chromobox protein 1 0.0114 0.0382 0.0382
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0049 0.0123 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0219 0.2482
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0037 0.0071
Loa Loa (eye worm) hypothetical protein 0.0233 0.0857 0.1644
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0219 0.0219
Echinococcus granulosus mitogen activated protein kinase 3 0.0112 0.0375 0.0375
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0037 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0037 0.0071
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0292 0.1095 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.003 0.0046 0.0482
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0317 0.1195 0.1195
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0088 0.1284
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0026 0.0031 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0209 0.0761 0.0761
Schistosoma mansoni ATP-binding cassette transporter 0.0114 0.0381 0.0381
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0189 0.0363
Echinococcus multilocularis NMDA receptor 0.0114 0.0381 0.0381
Schistosoma mansoni hypothetical protein 0.052 0.2008 0.2008
Brugia malayi MH1 domain containing protein 0.0021 0.0008 0.0015
Echinococcus multilocularis protein patched 0.0051 0.013 0.013
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.035 0.0672
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0037 0.0071
Echinococcus granulosus methyl CpG binding domain protein 2 0.0043 0.0096 0.0096
Schistosoma mansoni thyroid hormone receptor 0.0223 0.0819 0.0819
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0112 0.0375 0.4287
Brugia malayi hypothetical protein 0.0197 0.0713 0.1366
Schistosoma mansoni metabotropic glutamate receptor 0.0058 0.0159 0.0159
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0107 0.0353 0.4033
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0375 0.0631
Brugia malayi hypothetical protein 0.0026 0.003 0.0057
Echinococcus granulosus metabotropic glutamate receptor 5 0.0058 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0037 0.0072 0.0138
Loa Loa (eye worm) beta-lactamase 0.0023 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.018 0.0648 0.1242
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0199 0.2893
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0053 0.0139 0.0139
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.0019 0.0036
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.002 0.0004 0.0004
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0292 0.1095 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0036 0.007 0.007
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0028 0.0036 0.0371
Echinococcus multilocularis lysine specific demethylase 6a 0.0047 0.0113 0.0113
Loa Loa (eye worm) RNA binding protein 0.0248 0.0919 0.1761
Loa Loa (eye worm) hypothetical protein 0.0051 0.0131 0.025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0037 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0182 0.0656 0.0656
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0317 0.1195 0.1195
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0055 0.0145 0.0145
Brugia malayi Glutamate receptor 2 precursor 0.0114 0.0381 0.0731
Toxoplasma gondii PHD-finger domain-containing protein 0.0068 0.0199 0.2893
Schistosoma mansoni acyl-protein thioesterase 12 (lysophospholipase III) 0.0044 0.0102 0.0102
Loa Loa (eye worm) bromodomain containing protein 0.0047 0.0114 0.0219
Brugia malayi Glutamate receptor 1 precursor 0.0114 0.0381 0.0731
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.002 0.0004 0.0004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.003 0.0046 0.1125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0131 0.025
Brugia malayi beta-lactamase family protein 0.0023 0.0019 0.0036
Echinococcus granulosus tyrosine kinase 0.0058 0.0159 0.0159
Toxoplasma gondii Erv1 / Alr family protein 0.0028 0.0036 0.053
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0401 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0047 0.0113 0.5702
Loa Loa (eye worm) hypothetical protein 0.0059 0.0163 0.0312
Onchocerca volvulus 0.0023 0.0019 0.0032
Echinococcus multilocularis phd:f box containing protein 0.0047 0.0113 0.0113
Brugia malayi Doublecortin family protein 0.0052 0.0134 0.0258
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0072 0.0138
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0055 0.0146 0.043
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0069 0.0201 0.0338
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.051 0.5843
Schistosoma mansoni pyridoxine kinase 0.0026 0.003 0.003
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0172 0.0615 0.0615
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0124 0.0422 0.0422
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0058 0.0159 0.0305
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0047 0.0113 0.0113
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0026 0.0043
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0219 0.0219
Echinococcus granulosus Smad4 0.0021 0.0008 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0114 0.0382 0.0643
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0037 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0008 0.0015
Brugia malayi beta-lactamase family protein 0.0023 0.0019 0.0036
Toxoplasma gondii ABC1 family protein 0.0023 0.0019 0.0276
Schistosoma mansoni hypothetical protein 0.0049 0.0122 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0233 0.0857 0.0857
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0058 0.0621
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.021 0.0767 0.1471
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.003 0.0046 0.0088
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0021
Brugia malayi beta-lactamase 0.0023 0.0019 0.0036
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.004 0.0309
Brugia malayi metabotropic glutamate receptor type 2 0.0058 0.0159 0.0305
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0011 0.0043
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.004 0.2007
Brugia malayi F/Y-rich N-terminus family protein 0.0043 0.0096 0.0184
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0043 0.0098 0.0098
Schistosoma mansoni tar DNA-binding protein 0.0248 0.0919 0.0919
Onchocerca volvulus 0.0052 0.0134 0.0226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.021 0.0767 0.0767
Plasmodium falciparum T-complex protein 1 subunit beta 0.002 0.0004 0.0214
Schistosoma mansoni tyrosine kinase 0.0058 0.0159 0.0159
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0189 0.0189
Echinococcus multilocularis chromobox protein 1 0.0114 0.0382 0.0382
Onchocerca volvulus 0.005 0.0126 0.0212
Loa Loa (eye worm) T-complex protein 1 0.002 0.0004 0.0008
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0145 0.0145
Echinococcus multilocularis glutamate receptor 2 0.0114 0.0381 0.0381
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.051 0.5843
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.003 0.0046 0.0482
Onchocerca volvulus 0.0059 0.0163 0.0273
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.004 0.2007
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0112 0.0375 0.4287
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0236 0.0869 1
Brugia malayi ecdysteroid receptor 0.0028 0.0037 0.0071
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0107 0.0353 0.0353
Brugia malayi PHD-finger family protein 0.0067 0.0193 0.0371
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0026 0.0031 0.078
Echinococcus multilocularis Smad4 0.0021 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0107 0.0179
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0068
Echinococcus multilocularis glutamate receptor 2 0.0172 0.0615 0.0615
Loa Loa (eye worm) inositol-1 0.0055 0.0146 0.0281
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0028 0.0036 0.0036
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0037 0.0071
Loa Loa (eye worm) PHD-finger family protein 0.0052 0.0132 0.0254
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0023 0.0019 0.0035
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0233 0.0857 0.0857
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0031 0.0053
Schistosoma mansoni ap endonuclease 0.003 0.0046 0.0046
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0026 0.0031 0.073
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0292 0.1095 1
Brugia malayi Phospholipase/Carboxylesterase family protein 0.0044 0.0102 0.0195
Mycobacterium tuberculosis Conserved protein 0.0023 0.0019 0.0117
Echinococcus granulosus nmda type glutamate receptor 0.1112 0.4381 0.4381
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.004 0.004
Onchocerca volvulus 0.0209 0.0761 0.128
Echinococcus granulosus mitogen activated protein kinase 0.0112 0.0375 0.0375
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.021 0.0767 0.0767
Schistosoma mansoni hypothetical protein 0.0068 0.0199 0.0199
Echinococcus granulosus neuropeptide s receptor 0.0327 0.1236 0.1236
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0146 0.1643
Echinococcus multilocularis acyl protein thioesterase 12 0.0044 0.0102 0.0102
Echinococcus multilocularis Polycystic kidney disease protein 0.0052 0.0134 0.0134
Brugia malayi Pre-SET motif family protein 0.1321 0.5216 1
Brugia malayi MH2 domain containing protein 0.0302 0.1136 0.2178
Schistosoma mansoni hypothetical protein 0.0052 0.0132 0.0132
Loa Loa (eye worm) TAR-binding protein 0.0248 0.0919 0.1761
Brugia malayi Calcitonin receptor-like protein seb-1 0.0208 0.076 0.1457
Echinococcus multilocularis jumonji domain containing protein 0.0095 0.0306 0.0306
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0401 0.077
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.021 0.0767 0.1471
Schistosoma mansoni hypothetical protein 0.0195 0.0707 0.0707
Echinococcus granulosus lysine specific demethylase 6a 0.0047 0.0113 0.0113
Schistosoma mansoni chromobox protein 0.0114 0.0382 0.0382
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0008 0.004
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0446 0.0749
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0021 0.0008 0.0008
Toxoplasma gondii phospholipase/carboxylesterase 0.0044 0.0102 0.1482
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.0026 0.0026
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0172 0.0615 0.0615
Echinococcus multilocularis tar DNA binding protein 0.0248 0.0919 0.0919
Brugia malayi Receptor family ligand binding region containing protein 0.0058 0.0159 0.0305
Trypanosoma cruzi lysophospholipase, putative 0.0044 0.0102 0.1126
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0057
Brugia malayi glutaminase DH11.1 0.0825 0.323 0.6193
Echinococcus granulosus expressed conserved protein 0.0112 0.0373 0.0373
Brugia malayi T-complex protein 1, beta subunit 0.002 0.0004 0.0008
Onchocerca volvulus Huntingtin homolog 0.0197 0.0713 0.1198
Echinococcus granulosus glutamate receptor 2 0.0172 0.0615 0.0615
Schistosoma mansoni hypothetical protein 0.0066 0.0189 0.0189
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0008 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0202 0.295
Schistosoma mansoni smad1 5 8 and 0.0021 0.0008 0.0008
Echinococcus granulosus tar DNA binding protein 0.0248 0.0919 0.0919
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0011 0.001
Loa Loa (eye worm) runx1 0.004 0.0085 0.0162
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0107 0.0353 0.4033
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0305
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0043 0.0098 0.0188
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0113 0.1259
Schistosoma mansoni glutamate receptor NMDA 0.1226 0.4838 0.4838
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0043 0.0096 0.0096
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0031 0.0313
Echinococcus multilocularis mitogen activated protein kinase 3 0.0112 0.0375 0.0375
Echinococcus granulosus tumor protein p63 0.0776 0.3034 0.3034
Chlamydia trachomatis lysophospholipase esterase 0.0044 0.0102 0.0838
Onchocerca volvulus 0.0106 0.035 0.0589
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.003 0.0046 0.0482
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.0496 0.0951
Schistosoma mansoni pyridoxine kinase 0.0026 0.003 0.003
Brugia malayi RNA recognition motif domain containing protein 0.0248 0.0919 0.1761
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0037 0.0037
Brugia malayi Cytochrome P450 family protein 0.0043 0.0096 0.0184
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.003 0.0046 0.0046
Schistosoma mansoni glutamate receptor AMPA 0.0114 0.0381 0.0381
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.004 0.01
Schistosoma mansoni acyl-protein thioesterase 12 (lysophospholipase III) 0.0044 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0037 0.0071
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0058 0.0159 0.0305
Loa Loa (eye worm) hypothetical protein 0.0197 0.0713 0.1366
Giardia lamblia Kinase, CMGC MAPK 0.0112 0.0375 1
Loa Loa (eye worm) calpain family protein 1 0.0037 0.0072 0.0138
Trypanosoma cruzi ISWI complex protein 0.0038 0.0079 0.0861
Schistosoma mansoni jumonji domain containing protein 0.0271 0.1011 0.1011
Onchocerca volvulus 0.0059 0.0163 0.0273
Entamoeba histolytica phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative 0.0037 0.0075 0.1866
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0257
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0258
Brugia malayi Bromodomain containing protein 0.0192 0.0696 0.1335
Echinococcus granulosus Protein patched homolog 1 0.0051 0.013 0.013
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0066 0.0189 0.0189
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0028 0.0036 0.0036
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0154 0.0543 0.0543
Brugia malayi hypothetical protein 0.0052 0.0134 0.0258
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0114 0.0381 0.0381
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0031 0.006
Brugia malayi MAP kinase sur-1 0.0112 0.0375 0.0719
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0114 0.0381 0.0381
Mycobacterium ulcerans glutaminase 0.0825 0.323 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0233 0.0857 0.0857
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0026 0.0043
Schistosoma mansoni thyroid hormone receptor 0.0223 0.0819 0.0819
Brugia malayi hypothetical protein 0.004 0.0087 0.0167
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.004 0.01
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0088 0.1284
Mycobacterium tuberculosis Conserved hypothetical protein 0.0124 0.0423 0.3826
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0037 0.0071

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0022 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) 17.7828 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.0115 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 20.5878 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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