Detailed information for compound 951893

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 597.744 | Formula: C36H43N3O5
  • H donors: 1 H acceptors: 2 LogP: 3.82 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccccc1COCCCOc1ccc(cc1)C1=C([C@@H]2N[C@H](C1)CN(C2)C(=O)C)C(=O)N(CCc1ccccc1)C
  • InChi: 1S/C36H43N3O5/c1-26(40)39-23-30-22-32(35(33(24-39)37-30)36(41)38(2)19-18-27-10-5-4-6-11-27)28-14-16-31(17-15-28)44-21-9-20-43-25-29-12-7-8-13-34(29)42-3/h4-8,10-17,30,33,37H,9,18-25H2,1-3H3/t30-,33-/m1/s1
  • InChiKey: RILASFCKKNXOEA-LXANVCGNSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens renin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum plasmepsin I Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum Cathepsin D precursor, putative Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Renin, related Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi aspartyl protease, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin II Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus granulosus cathepsin d lysosomal aspartyl protease Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl protease ASP1 Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva cathepsin E, putative Get druggable targets OG5_126885 All targets in OG5_126885
Babesia bovis eukaryotic aspartyl protease family protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl proteinase (eimepsin), putative Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax aspartyl proteinase, putative Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva pepsinogen, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii plasmepsin Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum ko:K01379 cathepsin D [EC3.4.23.5], putative Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Pepsinogen A1, related Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) aspartic protease BmAsp-2 Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium hominis aspartyl protease precursor Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium parvum membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain Get druggable targets OG5_126885 All targets in OG5_126885
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum plasmepsin X renin 406 aa 352 aa 26.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2924 0.2796 0.2796
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.1271 0.1078 0.1077
Echinococcus multilocularis rho associated protein kinase 0.2036 0.1873 0.1872
Brugia malayi Serine/threonine-protein kinase SULU 0.2771 0.2638 0.2638
Echinococcus multilocularis heat shock protein 70 0.0323 0.0092 0.0091
Brugia malayi Hr1 repeat family protein 0.2326 0.2175 0.2175
Echinococcus granulosus retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Onchocerca volvulus 0.1052 0.085 0.1992
Trypanosoma brucei aurora B kinase 0.0866 0.0657 0.6047
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Onchocerca volvulus 0.0323 0.0092 0.0215
Schistosoma mansoni protein kinase 0.3794 0.3701 0.3695
Brugia malayi hypothetical protein 0.0305 0.0073 0.0073
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0617 0.0398 0.0398
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis epidermal growth factor receptor 0.6953 0.6986 0.6985
Brugia malayi Protein kinase domain containing protein 0.0658 0.044 0.044
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2771 0.2638 0.2637
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0323 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.1046 0.0843 0.0843
Echinococcus multilocularis protein KINase family member (kin 25) 0.0323 0.0092 0.0091
Onchocerca volvulus 0.0323 0.0092 0.0215
Onchocerca volvulus 0.0323 0.0092 0.0215
Brugia malayi Prion-like- 0.0336 0.0105 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Onchocerca volvulus 0.036 0.013 0.0305
Echinococcus multilocularis hemicentin 1 0.0336 0.0105 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1271 0.1078 1
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Entamoeba histolytica protein kinase domain containing protein 0.0315 0.0084 0.0833
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0285 0.0053 0.0053
Echinococcus multilocularis tyrosine protein kinase Src42A 0.145 0.1264 0.1263
Echinococcus multilocularis neuroglian 0.0438 0.0211 0.021
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus granulosus serine threonine protein kinase nrc 0.0391 0.0162 0.0162
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0084 0.0997
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma brucei protein kinase, putative 0.0456 0.0231 0.2047
Giardia lamblia Kinase, CAMK CAMKL 0.0453 0.0227 0.2604
Brugia malayi Protein kinase domain containing protein 0.0856 0.0646 0.0646
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus serine:threonine protein kinase 3 0.2543 0.24 0.2399
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0866 0.0657 0.0656
Trichomonas vaginalis protein kinase atn1, putative 0.0323 0.0092 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0323 0.0092 0.0091
Echinococcus multilocularis fibroblast growth factor receptor 4 0.2348 0.2197 0.2197
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0391 0.0162 0.2191
Brugia malayi Variant SH3 domain containing protein 0.0586 0.0365 0.0365
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0323 0.0092 0.0092
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0658 0.044 0.0439
Echinococcus multilocularis serine:threonine protein kinase N2 0.0658 0.044 0.0439
Brugia malayi Tyrosine-protein kinase abl-1 0.1753 0.1579 0.1579
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Trypanosoma cruzi cdc2-related kinase 1 0.0328 0.0097 0.0788
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0249 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0786 0.0573 0.0573
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0248 0.0014 0.0014
Echinococcus granulosus casein kinase I gamma 0.0541 0.0319 0.0318
Brugia malayi hypothetical protein 0.052 0.0297 0.0297
Echinococcus granulosus cGMP dependent protein kinase 1 0.0363 0.0134 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.2348 0.2197 0.2197
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0547 0.0325 0.0325
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0323 0.0092 0.0092
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.1271 0.1078 0.1077
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0315 0.0084 0.072
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0315 0.0084 0.0667
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0866 0.0657 0.6573
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Echinococcus granulosus dual specificity 0.1195 0.0999 0.0998
Onchocerca volvulus 0.0683 0.0466 0.1092
Loa Loa (eye worm) hypothetical protein 0.1052 0.085 0.085
Giardia lamblia Kinase, CMGC CDK 0.0328 0.0097 0.1019
Loa Loa (eye worm) TK/ALK protein kinase 0.2868 0.2738 0.2738
Loa Loa (eye worm) TK protein kinase 0.0323 0.0092 0.0092
Schistosoma mansoni tyrosine kinase 0.0545 0.0323 0.0314
Echinococcus granulosus dual specificity 0.0315 0.0084 0.0083
Schistosoma mansoni vesicular amine transporter 0.0568 0.0347 0.0338
Echinococcus multilocularis tyrosine protein kinase Fyn 0.145 0.1264 0.1263
Echinococcus granulosus receptor type guanylyl cyclase 0.0323 0.0092 0.0091
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0323 0.0092 0.1105
Plasmodium vivax tyrosine kinase-like protein, putative 0.0323 0.0092 0.1193
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0909 0.0702 0.0701
Trichomonas vaginalis STE family protein kinase 0.0367 0.0137 0.1712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0328 0.0097 0.0097
Entamoeba histolytica ankyrin repeat protein 0.0323 0.0092 0.0914
Trypanosoma cruzi protein kinase, putative 0.0323 0.0092 0.0743
Brugia malayi protein kinase C3,putative 0.048 0.0255 0.0255
Echinococcus granulosus tyrosine kinase 0.1224 0.1029 0.1028
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0453 0.0227 0.3114
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0247 0.0013 0.007
Brugia malayi Protein kinase domain containing protein 0.0965 0.0759 0.0759
Brugia malayi Protein kinase domain containing protein 0.6051 0.6048 0.6048
Schistosoma mansoni growth factor receptor-bound protein 0.059 0.037 0.0361
Trypanosoma brucei Casein kinase II 0.0285 0.0053 0.0375
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Brugia malayi bone morphogenetic protein type 1 receptor 0.0933 0.0726 0.0726
Echinococcus granulosus titin 0.0405 0.0177 0.0176
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Trypanosoma brucei protein kinase, putative 0.0248 0.0014 0.0014
Giardia lamblia Protein 21.1 0.0323 0.0092 0.0961
Echinococcus multilocularis myosin iiia 0.069 0.0473 0.0473
Brugia malayi C1-like domain containing protein 0.1136 0.0937 0.0937
Echinococcus granulosus twitchin 0.0871 0.0662 0.0661
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1195 0.0999 1
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Entamoeba histolytica hypothetical protein 0.0327 0.0096 0.0956
Schistosoma mansoni protein tyrosine kinase 0.0323 0.0092 0.0083
Loa Loa (eye worm) hypothetical protein 0.0336 0.0105 0.0105
Giardia lamblia Kinase, NEK 0.0323 0.0092 0.0961
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Entamoeba histolytica hypothetical protein 0.0324 0.0093 0.0928
Schistosoma mansoni protein kinase 0.0638 0.0419 0.0411
Brugia malayi protein kinase C II. 0.082 0.0608 0.0608
Brugia malayi Tyrosine-protein kinase PR2 0.0323 0.0092 0.0092
Giardia lamblia Kinase, CK1 Casein kinase 0.0305 0.0073 0.073
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Echinococcus multilocularis tyrosine protein kinase 0.2903 0.2775 0.2774
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0492 0.0268 0.0267
Echinococcus granulosus casein kinase I alpha 0.0305 0.0073 0.0072
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2128 0.1969 0.1968
Echinococcus granulosus tyrosine protein kinase csk 0.0323 0.0092 0.0091
Leishmania major protein kinase, putative 0.0323 0.0092 0.0802
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1136 0.0937 0.0937
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0909 0.0702 0.0693
Loa Loa (eye worm) hypothetical protein 0.1046 0.0843 0.0843
Echinococcus multilocularis twitchin 0.0303 0.0071 0.007
Loa Loa (eye worm) CAMK protein kinase 0.0405 0.0177 0.0177
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0327 0.0097 0.0096
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Entamoeba histolytica protein kinase, putative 0.0965 0.0759 0.7602
Schistosoma mansoni protein kinase 0.1809 0.1637 0.1629
Trichomonas vaginalis CMGC family protein kinase 0.0757 0.0543 0.7115
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Giardia lamblia Kinase, NEK 0.0367 0.0137 0.1514
Giardia lamblia Kinase, AGC AKT 0.1039 0.0836 1
Trypanosoma brucei Pseudokinase, putative 0.0323 0.0092 0.0743
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.036 0.013 0.013
Echinococcus multilocularis protein kinase 0.0323 0.0092 0.0091
Entamoeba histolytica protein kinase, putative 0.0866 0.0657 0.6573
Echinococcus multilocularis tensin 0.036 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.0093 0.1124
Echinococcus multilocularis protein tyrosine kinase 0.4391 0.4322 0.4322
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1195 0.0999 0.9259
Echinococcus granulosus tyrosine protein kinase pr2 0.0323 0.0092 0.0091
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0655 0.0437 0.3983
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0323 0.0092 0.0092
Schistosoma mansoni protein kinase 0.0933 0.0726 0.0718
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma cruzi casein kinase, putative 0.0305 0.0073 0.0564
Schistosoma mansoni serine/threonine-protein kinase 0.0441 0.0214 0.0205
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0328 0.0097 0.1169
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0586 0.0365 0.0357
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0323 0.0092 0.0091
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0287 0.0054 0.0662
Trichomonas vaginalis AGC family protein kinase 0.0866 0.0657 0.8632
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0323 0.0092 0.0091
Entamoeba histolytica protein kinase, putative 0.0243 0.0009 0.0083
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) hypothetical protein 0.1062 0.086 0.086
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2891 0.2762 0.2761
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.2348 0.2197 0.2197
Echinococcus multilocularis receptor type guanylyl cyclase 0.0323 0.0092 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma cruzi cdc2-related kinase 3 0.0328 0.0097 0.0788
Plasmodium falciparum protein kinase, putative 0.0456 0.0231 0.3165
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0013 0.0004
Schistosoma mansoni cell adhesion molecule 0.0336 0.0105 0.0096
Echinococcus multilocularis tyrosine kinase 0.0683 0.0466 0.0466
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Echinococcus granulosus serine:threonine protein kinase 0.0317 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.1415 0.1228 0.1228
Echinococcus multilocularis serine:threonine protein kinase 0.0317 0.0086 0.0085
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Brugia malayi Protein kinase domain containing protein 0.0704 0.0488 0.0488
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Loa Loa (eye worm) TK/ACK protein kinase 0.0323 0.0092 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0271 0.0038 0.0384
Trypanosoma cruzi polo-like protein kinase, putative 0.0617 0.0398 0.3619
Entamoeba histolytica protein kinase domain containing protein 0.0285 0.0053 0.0522
Brugia malayi serine/threonine-protein kinase PAK 7 0.235 0.22 0.22
Brugia malayi Protein kinase domain containing protein 0.0513 0.0289 0.0289
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0323 0.0092 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.2326 0.2175 0.2168
Echinococcus granulosus mitogen activated protein kinase 3 0.0248 0.0014 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0054 0.0046
Entamoeba histolytica protein kinase, putative 0.0355 0.0126 0.1253
Schistosoma mansoni hypothetical protein 0.036 0.013 0.0122
Giardia lamblia Kinase, CDC7 0.0262 0.0028 0.019
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.069 0.0473 0.4325
Echinococcus granulosus dual specificity 0.0315 0.0084 0.0083
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0248 0.0014 0.0014
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1224 0.1029 0.1028
Loa Loa (eye worm) hypothetical protein 0.0314 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0438 0.0211 0.0211
Echinococcus granulosus casein kinase I delta 0.0305 0.0073 0.0072
Schistosoma mansoni protein kinase 0.0355 0.0126 0.0117
Echinococcus granulosus tensin 0.036 0.013 0.013
Schistosoma mansoni tensin-related 0.036 0.013 0.0122
Onchocerca volvulus 0.0323 0.0092 0.0215
Echinococcus granulosus serine:threonine protein kinase N2 0.2326 0.2175 0.2174
Echinococcus multilocularis suppressor of cytokine signaling 6 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.1062 0.086 0.086
Echinococcus multilocularis tyrosine protein kinase otk 0.0336 0.0105 0.0105
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.0327 0.4244
Schistosoma mansoni protein kinase 0.0404 0.0177 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0084 0.0997
Brugia malayi Protein-tyrosine phosphatase containing protein 0.036 0.013 0.013
Trypanosoma cruzi cdc2-related kinase 1 0.0328 0.0097 0.0788
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.0177 0.0168
Entamoeba histolytica PH domain containing protein kinase, putative 0.0441 0.0214 0.214
Entamoeba histolytica PH domain containing protein kinase, putative 0.0705 0.0489 0.4893
Schistosoma mansoni protein kinase 0.0495 0.0271 0.0262
Entamoeba histolytica protein kinase , putative 0.0866 0.0657 0.6573
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.069 0.0473 0.4736
Brugia malayi Protein kinase domain containing protein 0.0683 0.0466 0.0466
Schistosoma mansoni myosin-binding protein-related 0.0271 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0438 0.0211 0.021
Loa Loa (eye worm) hypothetical protein 0.0305 0.0073 0.0073
Loa Loa (eye worm) casein kinase 0.0407 0.018 0.018
Echinococcus multilocularis serine threonine protein kinase 0.075 0.0536 0.0536
Brugia malayi Protein kinase domain containing protein 0.0683 0.0466 0.0466
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.6504 0.6519 0.6519
Entamoeba histolytica serine/threonine kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus fibroblast growth factor receptor 4 0.2348 0.2197 0.2197
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0391 0.0162 0.0162
Echinococcus granulosus integrin linked protein kinase 0.0323 0.0092 0.0091
Trichomonas vaginalis AGC family protein kinase 0.0704 0.0488 0.6386
Trypanosoma cruzi casein kinase II, putative 0.0285 0.0053 0.0375
Brugia malayi hypothetical protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) projectin 0.0271 0.0038 0.0038
Onchocerca volvulus 0.0323 0.0092 0.0215
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0305 0.0073 0.0073
Schistosoma mansoni tyrosine protein kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis tyrosine protein kinase Srms 0.1224 0.1029 0.1028
Plasmodium falciparum protein kinase, putative 0.0323 0.0092 0.1193
Entamoeba histolytica ankyrin repeat protein 0.0323 0.0092 0.0914
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0324 0.0093 0.0928
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0315 0.0084 0.0084
Loa Loa (eye worm) camk/dcamkl protein kinase 0.04 0.0172 0.0172
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0323 0.0092 0.1105
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0323 0.0092 0.0083
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.149 0.1306 0.1306
Giardia lamblia Kinase, CMGC MAPK 0.0248 0.0014 0.0018
Echinococcus multilocularis SH2 motif 0.036 0.013 0.013
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0617 0.0398 0.3909
Toxoplasma gondii STE kinase 0.0323 0.0092 0.1193
Plasmodium falciparum calcium-dependent protein kinase 4 0.0287 0.0054 0.0662
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Loa Loa (eye worm) hypothetical protein 0.1167 0.097 0.097
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0084 0.0997
Schistosoma mansoni adapter molecule crk 0.0586 0.0365 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.0097 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0323 0.0092 0.1105
Echinococcus granulosus casein kinase I delta 0.0305 0.0073 0.0072
Loa Loa (eye worm) thyroid receptor interactor 0.1159 0.0961 0.0961
Schistosoma mansoni serine/threonine protein kinase 0.1673 0.1496 0.1488
Loa Loa (eye worm) hypothetical protein 0.0735 0.052 0.052
Schistosoma mansoni serine/threonine protein kinase 0.1137 0.0938 0.093
Echinococcus multilocularis serine:threonine protein kinase 3 0.2543 0.24 0.2399
Onchocerca volvulus 0.0683 0.0466 0.1092
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Echinococcus multilocularis tyrosine protein kinase Src64B 0.145 0.1264 0.1263
Schistosoma mansoni tyrosine kinase 0.298 0.2855 0.2849
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0856 0.0646 0.0646
Brugia malayi SH2 domain containing protein 0.0683 0.0466 0.0466
Echinococcus granulosus protein kinase 0.1809 0.1637 0.1636
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0276 0.0043 0.0034
Schistosoma mansoni nephrin 0.0839 0.0629 0.062
Echinococcus multilocularis cyclin dependent kinase 1 0.0328 0.0097 0.0096
Echinococcus multilocularis NCK adaptor protein 0.059 0.037 0.0369
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Plasmodium falciparum tyrosine kinase-like protein 0.0323 0.0092 0.1193
Plasmodium falciparum serine/threonine protein kinase 0.0247 0.0013 0.007
Brugia malayi Variant SH3 domain containing protein 0.0586 0.0365 0.0365
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0919 0.0712 0.6565
Brugia malayi Tensin 0.036 0.013 0.013
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0315 0.0084 0.0667
Echinococcus granulosus SH2 domain containing adapter protein F 0.036 0.013 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0227 0.0218
Echinococcus granulosus tyrosine kinase 0.0683 0.0466 0.0466
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0656 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.224 0.2085 0.2085
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0323 0.0092 0.0091
Brugia malayi casein kinase 1, delta 0.0305 0.0073 0.0073
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.2543 0.24 0.24
Brugia malayi Protein kinase domain 0.0404 0.0177 0.0177
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.036 0.013 0.0305
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Onchocerca volvulus Tyrosine kinase homolog 0.4339 0.4268 1
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0933 0.0726 0.0726
Giardia lamblia Kinase, CMGC CDK 0.0328 0.0097 0.1019
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0655 0.0437 0.3983
Entamoeba histolytica serine/threonine kinase, putative 0.0323 0.0092 0.0914
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0453 0.0227 0.2013
Loa Loa (eye worm) AGC/PKA protein kinase 0.0655 0.0437 0.0437
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0319 0.0088 0.0087
Echinococcus multilocularis casein kinase I delta 0.0305 0.0073 0.0072
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0287 0.0054 0.0054
Entamoeba histolytica protein kinase, putative 0.0404 0.0177 0.1764
Echinococcus multilocularis casein kinase i 0.0305 0.0073 0.0072
Leishmania major protein kinase, putative 0.0456 0.0231 0.2211
Echinococcus granulosus MAM 0.0305 0.0073 0.0072
Loa Loa (eye worm) TK protein kinase 0.2903 0.2775 0.2774
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0227 0.0218
Echinococcus granulosus suppressor of cytokine signaling 6 0.036 0.013 0.013
Entamoeba histolytica casein kinase, putative 0.0305 0.0073 0.0724
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0363 0.0134 0.0133
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0038 0.0038
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Schistosoma mansoni cell adhesion molecule 0.0271 0.0038 0.0029
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.036 0.013 0.013
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0328 0.0097 0.1262
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Temporarily assigned gene name protein 59 0.1271 0.1078 0.1078
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0287 0.0054 0.0054
Echinococcus multilocularis casein kinase I delta 0.0305 0.0073 0.0072
Echinococcus granulosus hemicentin 1 0.0336 0.0105 0.0105
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Leishmania major casein kinase II, putative 0.0285 0.0053 0.0405
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0683 0.0466 0.4664
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus multilocularis natriuretic peptide receptor 1 0.0323 0.0092 0.0091
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0655 0.0437 0.6095
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0323 0.0092 0.1193
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0264 0.0031 0.003
Loa Loa (eye worm) TK/FAK protein kinase 0.444 0.4372 0.4372
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0413 0.0185 0.0185
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0586 0.0365 0.0365
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1271 0.1078 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0363 0.0134 0.0133
Entamoeba histolytica hypothetical protein 0.0276 0.0043 0.0425
Schistosoma mansoni serine/threonine protein kinase 0.0655 0.0437 0.0428
Brugia malayi Protein kinase domain containing protein 0.0541 0.0319 0.0319
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.3794 0.3701 0.3701
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0305 0.0073 0.0564
Brugia malayi p70 ribosomal S6 kinase beta 0.0915 0.0707 0.0707
Leishmania major protein kinase, putative 0.0919 0.0712 0.7091
Echinococcus granulosus cGMP dependent protein kinase 0.0363 0.0134 0.0133
Schistosoma mansoni serine/threonine kinase 0.0658 0.044 0.0432
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0285 0.0053 0.0638
Brugia malayi Protein kinase domain containing protein 0.0618 0.0399 0.0399
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0287 0.0054 0.0392
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase csk 0.0323 0.0092 0.0091
Onchocerca volvulus 0.0323 0.0092 0.0215
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0655 0.0437 0.3983
Toxoplasma gondii casein kinase I 0.0305 0.0073 0.0923
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Echinococcus multilocularis aurora kinase A 0.0866 0.0657 0.0656
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0919 0.0712 0.6565
Echinococcus multilocularis tyrosine protein kinase Fgr 0.145 0.1264 0.1263
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) SH2 domain-containing protein 0.036 0.013 0.013
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0866 0.0657 0.0656
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0323 0.0092 0.0092
Echinococcus multilocularis cyclin dependent kinase 1 0.0328 0.0097 0.0096
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0658 0.044 0.0439
Brugia malayi Immunoglobulin I-set domain containing protein 0.4904 0.4856 0.4856
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.6475 0.6489 0.6489
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.0134 0.0125
Schistosoma mansoni protein kinase 0.104 0.0837 0.0829
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.149 0.1306 0.1305
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0336 0.0105 0.0105
Giardia lamblia Kinase, AGC PKA 0.0655 0.0437 0.5152
Echinococcus multilocularis CDC7 cell division cycle 7 0.0262 0.0028 0.0028
Echinococcus multilocularis mitogen activated protein kinase 3 0.0248 0.0014 0.0014
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.036 0.013 0.013
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis STE family protein kinase 0.0404 0.0177 0.2235
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.3794 0.3701 0.3701
Echinococcus granulosus growth factor receptor bound protein 2 0.059 0.037 0.0369
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0323 0.0092 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1369 0.1179 0.1179
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Protein kinase domain containing protein 0.0549 0.0327 0.0327
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0248 0.0014 0.0014
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Loa Loa (eye worm) hypothetical protein 0.0314 0.0082 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.1563 0.1381 0.1373
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0328 0.0097 0.0097
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) TK/DDR protein kinase 0.0323 0.0092 0.0092
Leishmania major protein kinase, putative 0.0866 0.0657 0.6531
Brugia malayi Immunoglobulin I-set domain containing protein 0.0336 0.0105 0.0105
Toxoplasma gondii aurora kinase 0.0866 0.0657 0.9216
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0617 0.0398 0.0398
Echinococcus granulosus protein kinase C gamma type 0.075 0.0536 0.0536
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0323 0.0092 0.0083
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Echinococcus granulosus TGF-beta receptor type-1 0.0744 0.0529 0.0529
Echinococcus granulosus tyrosine protein kinase Blk 0.1224 0.1029 0.1028
Echinococcus multilocularis SH2 motif 0.036 0.013 0.013
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus granulosus expressed protein 0.0247 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0314 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.0247 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Echinococcus granulosus Vam6:Vps39 protein 0.1271 0.1078 0.1077
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0271 0.0038 0.0038
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0328 0.0097 0.0851
Leishmania major protein kinase A catalytic subunit isoform 2 0.0655 0.0437 0.4302
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0328 0.0097 0.0851
Loa Loa (eye worm) hypothetical protein 0.0568 0.0347 0.0347
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0919 0.0712 0.6565
Echinococcus multilocularis ephrin type A receptor 4 A 0.0468 0.0242 0.0242
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.235 0.22 0.22
Echinococcus granulosus serine:threonine protein kinase 0.0317 0.0086 0.0085
Trypanosoma cruzi aurora B kinase, putative 0.0866 0.0657 0.6047
Entamoeba histolytica protein kinase, putative 0.0757 0.0543 0.5433
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0547 0.0325 0.0325
Echinococcus granulosus protein tyrosine kinase 0.4391 0.4322 0.4322
Echinococcus granulosus serine:threonine kinase SAD 1 0.0453 0.0227 0.0227
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0658 0.044 0.0439
Echinococcus granulosus CDC7 cell division cycle 7 0.0262 0.0028 0.0028
Loa Loa (eye worm) protein kinase domain-containing protein 0.0541 0.0319 0.0319
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0453 0.0227 0.2174
Trichomonas vaginalis CMGC family protein kinase 0.0248 0.0014 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.0054 0.0607
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Plasmodium falciparum calcium-dependent protein kinase 1 0.0287 0.0054 0.0662
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Onchocerca volvulus 0.0407 0.0179 0.0419
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni tyrosine kinase 0.2702 0.2566 0.2559
Trypanosoma brucei polo-like protein kinase 0.0617 0.0398 0.3619
Onchocerca volvulus 0.0262 0.0028 0.0067
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0271 0.0038 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Echinococcus granulosus hypothetical protein 0.0786 0.0573 0.0572
Giardia lamblia Kinase 0.0323 0.0092 0.0961
Loa Loa (eye worm) hypothetical protein 0.1002 0.0798 0.0798
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Echinococcus granulosus epidermal growth factor receptor 0.6953 0.6986 0.6985
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.0093 0.1124
Brugia malayi hypothetical protein 0.1271 0.1078 0.1078
Schistosoma mansoni ephrin receptor 0.0468 0.0242 0.0234
Brugia malayi Protein kinase domain containing protein 0.0243 0.0009 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0248 0.0014 0.0071
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0843 0.0633 0.0633
Brugia malayi Peroxidasin 0.0337 0.0107 0.0107
Schistosoma mansoni GTPase activating protein 0.036 0.013 0.0122
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0453 0.0227 0.0227
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0419 0.0191 0.1678
Trypanosoma cruzi protein kinase, putative 0.0323 0.0092 0.0743
Echinococcus granulosus dual specificity protein kinase clk2 0.0919 0.0712 0.0711
Onchocerca volvulus Serine\/threonine kinase homolog 0.043 0.0203 0.0476
Schistosoma mansoni tyrosine kinase 0.145 0.1264 0.1256
Echinococcus granulosus tyrosine protein kinase Fyn 0.145 0.1264 0.1263
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1039 0.0836 0.0836
Onchocerca volvulus 0.3847 0.3756 0.8801
Echinococcus granulosus insulin growth factor 1 receptor beta 0.6475 0.6489 0.6489
Trichomonas vaginalis AGC family protein kinase 0.0655 0.0437 0.5704
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Entamoeba histolytica SH2 domain containing protein 0.036 0.013 0.13
Schistosoma mansoni serine/threonine protein kinase 0.1673 0.1496 0.1488
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.1271 0.1078 0.107
Echinococcus granulosus rho-associated protein kinase 1 0.2036 0.1873 0.1872
Echinococcus granulosus protein kinase c iota type 0.1004 0.08 0.08
Trichomonas vaginalis TKL family protein kinase 0.0324 0.0093 0.1124
Schistosoma mansoni hypothetical protein 0.0305 0.0073 0.0064
Plasmodium vivax serine/threonine kinase-1, putative 0.0919 0.0712 1
Echinococcus multilocularis SHC transforming protein 3 0.036 0.013 0.013
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis mitogen activated protein kinase 14 0.0419 0.0191 0.0191
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2771 0.2638 0.2637
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni tyrosine kinase 0.2531 0.2387 0.2381
Echinococcus granulosus tyrosine protein kinase shark 0.298 0.2855 0.2855
Loa Loa (eye worm) hypothetical protein 0.197 0.1804 0.1804
Echinococcus granulosus neuroglian 0.0438 0.0211 0.021
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0336 0.0105 0.0105
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0521 0.0298 0.0297
Trichomonas vaginalis protein tyrosine kinase, putative 0.0323 0.0092 0.1105
Brugia malayi hypothetical protein 0.036 0.013 0.013
Trichomonas vaginalis STE family protein kinase 0.069 0.0473 0.6189
Schistosoma mansoni tyrosine kinase 0.0909 0.0701 0.0693
Trichomonas vaginalis TK family protein kinase 0.0324 0.0093 0.1124
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0919 0.0712 0.0712
Echinococcus granulosus protein kinase shaggy 0.0757 0.0543 0.0542
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0568 0.0347 0.0346
Giardia lamblia Kinase, NEK 0.0367 0.0137 0.1514
Brugia malayi STE20-like kinase MST 0.2543 0.24 0.24
Echinococcus granulosus aurora kinase A 0.0866 0.0657 0.0656
Brugia malayi intracellular kinase 0.0757 0.0543 0.0543
Loa Loa (eye worm) protein kinase domain-containing protein 0.0323 0.0092 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0084 0.0997
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni tyrosine kinase 0.4391 0.4322 0.4317
Echinococcus granulosus cyclin dependent kinase 5 0.0328 0.0097 0.0096
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.036 0.013 0.0122
Echinococcus multilocularis roundabout 2 0.1006 0.0802 0.0801
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0287 0.0054 0.0054
Echinococcus granulosus cyclin dependent kinase 1 0.0328 0.0097 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0323 0.0092 0.0215
Brugia malayi Protein kinase domain containing protein 0.1415 0.1228 0.1228
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.043 0.0203 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0257 0.0249
Giardia lamblia Kinase, PLK 0.0617 0.0398 0.4681
Brugia malayi Protein kinase domain containing protein 0.0683 0.0466 0.0466
Entamoeba histolytica protein kinase, putative 0.0287 0.0054 0.0539
Giardia lamblia Kinase, CMGC CK2 0.0285 0.0053 0.0486
Loa Loa (eye worm) TK protein kinase 0.0323 0.0092 0.0092
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.095 0.0744 0.0744
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0287 0.0054 0.0054
Loa Loa (eye worm) serine/threonine protein kinase 0.0323 0.0092 0.0092
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0919 0.0712 0.6565
Echinococcus multilocularis tyrosine protein kinase Fyn 0.145 0.1264 0.1263
Onchocerca volvulus 0.0405 0.0177 0.0414
Schistosoma mansoni tyrosine kinase 0.9852 1 1
Loa Loa (eye worm) TK protein kinase 0.1009 0.0805 0.0805
Echinococcus granulosus tyrosine protein kinase otk 0.0336 0.0105 0.0105
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Trichomonas vaginalis CK1 family protein kinase 0.0305 0.0073 0.0851
Trypanosoma cruzi cdc2-related kinase 3 0.0328 0.0097 0.0788
Brugia malayi Protein kinase domain containing protein 0.0495 0.0271 0.0271
Schistosoma mansoni cell adhesion molecule 0.0836 0.0626 0.0617
Loa Loa (eye worm) TK protein kinase 0.0323 0.0092 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Onchocerca volvulus 0.036 0.013 0.0305
Echinococcus multilocularis roundabout 2 0.0438 0.0211 0.021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0336 0.0105 0.0105
Echinococcus multilocularis signal transduction protein lnk realted 0.036 0.013 0.013
Loa Loa (eye worm) RGC/RGC protein kinase 0.0323 0.0092 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.082 0.0608 0.06
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0757 0.0543 0.0543
Echinococcus multilocularis tyrosine protein kinase csk 0.0323 0.0092 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0328 0.0097 0.1169
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Echinococcus granulosus expressed conserved protein 0.036 0.013 0.013
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi tRNA modification GTPase TrmE family protein 0.036 0.013 0.013
Loa Loa (eye worm) CDC7 protein kinase 0.0262 0.0028 0.0028
Plasmodium falciparum glycogen synthase kinase 3 0.0757 0.0543 0.7599
Echinococcus granulosus suppressor of cytokine signaling 7 0.036 0.013 0.013
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus tyrosine protein kinase Fyn 0.145 0.1264 0.1263
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.095 0.0744 0.0743
Onchocerca volvulus 0.0262 0.0028 0.0067
Brugia malayi Protein kinase domain containing protein 0.2293 0.214 0.214
Trichomonas vaginalis AGC family protein kinase 0.0658 0.044 0.5745
Echinococcus granulosus tyrosine protein kinase Srms 0.1604 0.1424 0.1424
Schistosoma mansoni protein kinase 0.308 0.2958 0.2952
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0519 0.0296 0.0295
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.145 0.1264 0.1263
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0319 0.0088 0.0087
Giardia lamblia Kinase, STE STE20 0.0404 0.0177 0.1991
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0323 0.0092 0.0091
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0305 0.0073 0.0073
Leishmania major protein kinase A catalytic subunit 0.0655 0.0437 0.4302
Echinococcus granulosus tyrosine protein kinase Fyn 0.145 0.1264 0.1263
Trichomonas vaginalis conserved hypothetical protein 0.0323 0.0092 0.1105
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0323 0.0092 0.0092
Entamoeba histolytica protein kinase, putative 0.0406 0.0178 0.1774
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Toxoplasma gondii AGC kinase 0.0655 0.0437 0.6095
Loa Loa (eye worm) protein-tyrosine phosphatase 0.036 0.013 0.013
Loa Loa (eye worm) TK/FER protein kinase 0.0683 0.0466 0.0466
Echinococcus granulosus TGF beta receptor type 1 0.0744 0.0529 0.0529
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0654 0.0436 0.0436
Giardia lamblia Kinase, CMGC CLK 0.0919 0.0712 0.8492
Brugia malayi Fes/CIP4 homology domain containing protein 0.1159 0.0961 0.0961
Brugia malayi Fibronectin type III domain containing protein 0.067 0.0453 0.0453
Entamoeba histolytica hypothetical protein 0.0324 0.0093 0.0928
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0323 0.0092 0.0092
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0243 0.0009 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.1369 0.1179 0.1179
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0568 0.0347 0.0338
Echinococcus multilocularis suppressor of cytokine signaling 7 0.036 0.013 0.013
Schistosoma mansoni protein kinase 0.0305 0.0073 0.0064
Schistosoma mansoni vam6/vps39 related 0.1271 0.1078 0.107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0438 0.0211 0.0211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0268 0.0035 0.0035
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0323 0.0092 0.0743
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0323 0.0092 0.0083
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Trichomonas vaginalis AGC family protein kinase 0.0754 0.054 0.7079
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0655 0.0437 0.3983
Brugia malayi Protein kinase domain containing protein 0.0919 0.0712 0.0712
Echinococcus multilocularis protein kinase 0.0323 0.0092 0.0091
Trichomonas vaginalis AGC family protein kinase 0.0866 0.0657 0.8632
Trichomonas vaginalis CMGC family protein kinase 0.0919 0.0712 0.9368
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Brugia malayi Protein kinase domain containing protein 0.0328 0.0097 0.0097
Plasmodium falciparum protein kinase, putative 0.0323 0.0092 0.1193
Trichomonas vaginalis CAMK family protein kinase 0.0345 0.0114 0.1407
Echinococcus multilocularis tensin 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0319 0.0088 0.0088
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0271 0.0038 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi protein unc-22 0.0405 0.0177 0.0177
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1271 0.1078 1
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni suppressor of cytokine signaling 0.036 0.013 0.0122
Brugia malayi Immunoglobulin I-set domain containing protein 0.0336 0.0105 0.0105
Echinococcus multilocularis casein kinase I alpha 0.0305 0.0073 0.0072
Loa Loa (eye worm) TK/Met protein kinase 0.0323 0.0092 0.0092
Trichomonas vaginalis STE family protein kinase 0.0355 0.0126 0.1556
Plasmodium vivax calcium-dependent protein kinase, putative 0.0287 0.0054 0.0662
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0038 0.0038
Echinococcus multilocularis growth factor receptor bound protein 2 0.0586 0.0365 0.0365
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0323 0.0092 0.1105
Echinococcus granulosus ephrin type A receptor 4 A 0.0468 0.0242 0.0242
Trypanosoma brucei cdc2-related kinase 3 0.0328 0.0097 0.0788
Echinococcus multilocularis mitogen activated protein kinase 14 0.0419 0.0191 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0014 0.0005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0617 0.0398 0.3983
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0268 0.0035 0.0034
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Echinococcus granulosus NDR protein kinase 0.0658 0.044 0.0439
Trichomonas vaginalis CMGC family protein kinase 0.0262 0.0028 0.026
Echinococcus multilocularis expressed protein 0.0247 0.0013 0.0012
Entamoeba histolytica protein kinase, putative 0.0965 0.0759 0.7602
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1224 0.1029 0.1028
Echinococcus granulosus roundabout 2 0.0438 0.0211 0.021
Echinococcus multilocularis PAK box P21 Rho binding 0.0355 0.0126 0.0125
Plasmodium vivax glycogen synthase kinase 3, putative 0.0757 0.0543 0.7599
Loa Loa (eye worm) SH2 domain-containing protein 0.036 0.013 0.013
Brugia malayi cell division control protein 2 homolog 0.0328 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0319 0.0088 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.0134 0.0126
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Loa Loa (eye worm) hypothetical protein 0.057 0.0348 0.0348
Loa Loa (eye worm) TK/ROR protein kinase 0.0492 0.0268 0.0268
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0268 0.0035 0.0035
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0547 0.0325 0.0325
Trypanosoma cruzi casein kinase, putative 0.0305 0.0073 0.0564
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.0289 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1177 0.0979 0.0979
Brugia malayi hypothetical protein 0.0319 0.0088 0.0088
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) RGC/RGC protein kinase 0.0323 0.0092 0.0092
Echinococcus multilocularis Immunoglobulin 0.0568 0.0347 0.0346
Schistosoma mansoni tyrosine kinase 0.6373 0.6383 0.638
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0248 0.0014 0.0091
Loa Loa (eye worm) AGC/NDR protein kinase 0.0658 0.044 0.044
Onchocerca volvulus 0.0673 0.0456 0.1068
Plasmodium vivax protein kinase, putative 0.0357 0.0127 0.1697
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Brugia malayi casein kinase I 0.0305 0.0073 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.0134 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0771 0.0558 0.0549
Entamoeba histolytica hypothetical protein, conserved 0.0323 0.0092 0.0914
Onchocerca volvulus 0.0305 0.0073 0.0171
Plasmodium falciparum NIMA related kinase 1 0.0367 0.0137 0.1841
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0757 0.0543 0.0542
Echinococcus multilocularis death associated protein kinase 1 0.1977 0.1811 0.1811
Echinococcus multilocularis casein kinase I gamma 0.0541 0.0319 0.0318
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0517 0.0294 0.0293
Onchocerca volvulus 0.0843 0.0633 0.1483
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0038 0.0038
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0519 0.0296 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0866 0.0657 0.8632
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0438 0.0211 0.021
Onchocerca volvulus 0.036 0.013 0.0305
Loa Loa (eye worm) AGC/PKA protein kinase 0.0655 0.0437 0.0437
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0633 0.0414 0.0414
Loa Loa (eye worm) TK/EPH protein kinase 0.0507 0.0284 0.0284
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0494 0.0269 0.2691
Echinococcus granulosus titin 0.0405 0.0177 0.0176
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.1271 0.1078 0.107
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Brugia malayi Protein kinase domain containing protein 0.0262 0.0028 0.0028
Schistosoma mansoni nephrin 0.0438 0.0211 0.0202
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.063 0.0411 0.0411
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Brugia malayi Tyrosine-protein kinase abl-1 0.1364 0.1174 0.1174
Schistosoma mansoni serine/threonine-protein kinase 0.0441 0.0214 0.0205
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.149 0.1306 0.1306
Echinococcus granulosus serine:threonine protein kinase mig 15 0.2946 0.282 0.2819
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0638 0.0419 0.0419
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.057 0.0349 0.4535
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0856 0.0646 0.0646
Schistosoma mansoni serine/threonine protein kinase 0.2036 0.1873 0.1866
Trypanosoma cruzi casein kinase, putative 0.0305 0.0073 0.0564
Plasmodium falciparum cGMP-dependent protein kinase 0.0363 0.0134 0.1789
Loa Loa (eye worm) hypothetical protein 0.0655 0.0437 0.0437
Schistosoma mansoni serine/threonine protein kinase 0.1195 0.0999 0.0991
Echinococcus multilocularis calcium activated potassium channel 0.0364 0.0134 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0866 0.0657 0.6573
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Plasmodium vivax tyrosine kinase-like protein, putative 0.0323 0.0092 0.1193
Echinococcus multilocularis dual specificity 0.0315 0.0084 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0323 0.0092 0.0092
Schistosoma mansoni signal transduction protein lnk-related 0.036 0.013 0.0122
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.069 0.0473 0.4325
Echinococcus multilocularis tyrosine protein kinase Abl 0.1753 0.1579 0.1578
Loa Loa (eye worm) TK/EGFR protein kinase 0.9852 1 1
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0264 0.0031 0.003
Echinococcus granulosus signal transduction protein lnk realted 0.036 0.013 0.013
Echinococcus granulosus calcium activated potassium channel 0.0364 0.0134 0.0134
Schistosoma mansoni tensin 0.036 0.013 0.0122
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0404 0.0176 0.0168
Onchocerca volvulus 0.0683 0.0466 0.1092
Brugia malayi Protein kinase domain containing protein 0.1415 0.1228 0.1228
Trichomonas vaginalis CMGC family protein kinase 0.0262 0.0028 0.026
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1195 0.0999 0.0999
Echinococcus granulosus protein kinase 0.0323 0.0092 0.0091
Plasmodium falciparum serine/threonine protein kinase KIN 0.0453 0.0227 0.3114
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0977 0.0772 0.0772
Echinococcus granulosus activated cdc42 kinase 1 0.0323 0.0092 0.0091
Brugia malayi Temporarily assigned gene name protein 59 0.0292 0.0059 0.0059
Echinococcus granulosus peroxidasin 0.0337 0.0107 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Schistosoma mansoni tyrosine-protein kinase zap-70 0.036 0.013 0.0122
Echinococcus granulosus serine/threonine protein kinase 0.0441 0.0214 0.0214
Toxoplasma gondii protein kinase 0.0323 0.0092 0.1193
Echinococcus multilocularis serine:threonine protein kinase 38 0.0658 0.044 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0227 0.0218
Schistosoma mansoni tyrosine kinase 0.0659 0.0441 0.0432
Schistosoma mansoni serine/threonine protein kinase 0.0919 0.0712 0.0704
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Echinococcus multilocularis 0.1809 0.1637 0.1636
Loa Loa (eye worm) TKL/LRRK protein kinase 0.063 0.0411 0.0411
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0287 0.0054 0.0662
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.145 0.1264 0.1263
Echinococcus multilocularis neuroglian 0.0737 0.0523 0.0522
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0367 0.0137 0.1841
Brugia malayi Protein kinase domain containing protein 0.6373 0.6383 0.6383
Echinococcus multilocularis tyrosine kinase 0.0323 0.0092 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus granulosus tyrosine protein kinase csk 0.0323 0.0092 0.0091
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Loa Loa (eye worm) AGC/PKG protein kinase 0.0363 0.0134 0.0134
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Brugia malayi Immunoglobulin I-set domain containing protein 0.0405 0.0177 0.0177
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.036 0.013 0.013
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.069 0.0473 0.4736
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0656 0.0439 0.0438
Echinococcus granulosus mitogen activated protein kinase 11 0.0419 0.0191 0.0191
Echinococcus granulosus tyrosine kinase 0.0323 0.0092 0.0091
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Immunoglobulin I-set domain containing protein 0.2517 0.2373 0.2373
Entamoeba histolytica tyrosin kinase, putative 0.0323 0.0092 0.0914
Echinococcus multilocularis protein kinase c iota type 0.1004 0.08 0.08
Schistosoma mansoni serine/threonine RGC 0.0323 0.0092 0.0083
Onchocerca volvulus 0.0271 0.0038 0.0089
Schistosoma mansoni neuroglian 0.0438 0.0211 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Trichomonas vaginalis AGC family protein kinase 0.0367 0.0137 0.1712
Giardia lamblia Kinase, CMGC DYRK 0.0315 0.0084 0.0863
Schistosoma mansoni tyrosine kinase 0.663 0.665 0.6647
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2128 0.1969 0.1968
Schistosoma mansoni protein kinase 0.104 0.0837 0.0829
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2924 0.2796 0.2796
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0323 0.0092 0.0092
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Brugia malayi STAT protein, DNA binding domain containing protein 0.036 0.013 0.013
Echinococcus multilocularis transfer RNA-Thr 0.0323 0.0092 0.0091
Entamoeba histolytica receptor protein kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) TK/ABL protein kinase 0.2891 0.2762 0.2762
Echinococcus granulosus N chimaerin 0.0519 0.0296 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0856 0.0646 0.0638
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0655 0.0437 0.3983
Loa Loa (eye worm) hypothetical protein 0.0336 0.0105 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Plasmodium falciparum calcium-dependent protein kinase 2 0.0287 0.0054 0.0662
Entamoeba histolytica hypothetical protein 0.0324 0.0093 0.0928
Schistosoma mansoni ste20-related kinase 0.1986 0.1821 0.1814
Schistosoma mansoni protein kinase 0.104 0.0837 0.0829
Schistosoma mansoni serine/threonine protein kinase 0.2523 0.2379 0.2373
Echinococcus granulosus Immunoglobulin 0.0568 0.0347 0.0346
Echinococcus multilocularis titin 0.0405 0.0177 0.0176
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Echinococcus granulosus dual specificity 0.0315 0.0084 0.0083
Brugia malayi Cam kinase protein 1 0.0287 0.0054 0.0054
Echinococcus granulosus cyclin dependent kinase 19 0.0404 0.0176 0.0176
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.145 0.1264 0.1263
Loa Loa (eye worm) gastrulation defective protein 1 0.0271 0.0038 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.0134 0.0126
Loa Loa (eye worm) TK protein kinase 0.0323 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0972 0.0766 0.0766
Schistosoma mansoni tyrosine kinase 0.6373 0.6383 0.638
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0328 0.0097 0.0096
Echinococcus multilocularis SH2 motif 0.036 0.013 0.013
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.036 0.013 0.013
Brugia malayi map kinase activated protein kinase protein 2 0.095 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.0586 0.0365 0.0365
Schistosoma mansoni protein kinase 0.0744 0.0529 0.0521
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0618 0.0399 0.0399
Schistosoma mansoni tyrosine kinase 0.663 0.665 0.6647
Entamoeba histolytica serine/threonine kinase, putative 0.0323 0.0092 0.0914
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0323 0.0092 0.0091
Onchocerca volvulus 0.1902 0.1734 0.4063
Plasmodium falciparum serine/threonine protein kinase, putative 0.0866 0.0657 0.9216
Entamoeba histolytica protein kinase, putative 0.0315 0.0084 0.0833
Echinococcus multilocularis 0.036 0.013 0.013
Echinococcus granulosus nervana 2 0.0257 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0305 0.0073 0.0073
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1404 0.1216 0.1216
Trichomonas vaginalis CAMK family protein kinase 0.0319 0.0088 0.1053
Brugia malayi hypothetical protein 0.2771 0.2638 0.2638
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0404 0.0177 0.0176
Schistosoma mansoni growth factor receptor-bound protein 0.0586 0.0365 0.0357
Onchocerca volvulus Serine\/threonine kinase homolog 0.0617 0.0398 0.0933
Trichomonas vaginalis STE family protein kinase 0.0404 0.0177 0.2235
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0323 0.0092 0.0914
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0456 0.0231 0.2047
Echinococcus granulosus tyrosine protein kinase Lyn 0.1584 0.1403 0.1402
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Brugia malayi probable protein kinase 0.308 0.2958 0.2958
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni nck2/grb4 0.0586 0.0365 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0617 0.0398 0.039
Echinococcus multilocularis peroxidasin 0.0337 0.0107 0.0106
Schistosoma mansoni suppressor of cytokine signaling 0.036 0.013 0.0122
Brugia malayi Immunoglobulin I-set domain containing protein 0.0336 0.0105 0.0105
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0248 0.0014 0.0015
Echinococcus granulosus tyrosine protein kinase ABL1 0.2891 0.2762 0.2761
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0438 0.0211 0.021
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0519 0.0296 0.0295
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0617 0.0398 0.0398
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0655 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.258 0.2439 0.2439
Schistosoma mansoni hypothetical protein 0.036 0.013 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0319 0.0088 0.1053
Giardia lamblia Kinase, CMGC GSK 0.0757 0.0543 0.6439
Echinococcus multilocularis mitogen activated protein kinase 11 0.0419 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.1271 0.1078 0.1078
Trypanosoma brucei Flagellum attachment zone protein 20 0.0323 0.0092 0.0743
Loa Loa (eye worm) RGC/RGC protein kinase 0.0323 0.0092 0.0092
Plasmodium falciparum calcium-dependent protein kinase 5 0.0287 0.0054 0.0662
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica protein kinase, putative 0.0494 0.0269 0.2691
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0323 0.0092 0.0083
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0655 0.0437 0.3983
Loa Loa (eye worm) hypothetical protein 0.0568 0.0347 0.0347
Echinococcus multilocularis activin receptor type 0.3573 0.3471 0.3471
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0323 0.0092 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0038 0.0038
Brugia malayi MAP kinase sur-1 0.0248 0.0014 0.0014
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0404 0.0177 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0328 0.0097 0.118
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0438 0.0211 0.021
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) TK protein kinase 0.2517 0.2373 0.2373
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0323 0.0092 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni hemicentin 0.0271 0.0038 0.0029
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0419 0.0191 0.1812
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni tyrosine kinase 0.2348 0.2197 0.219
Brugia malayi phosphoinositide-dependent protein kinase I 0.0243 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase csk 0.0323 0.0092 0.0091
Loa Loa (eye worm) AGC/AKT protein kinase 0.0965 0.0759 0.0759
Entamoeba histolytica protein kinase domain containing protein 0.0757 0.0543 0.5433
Echinococcus multilocularis Glutaredoxin protein 5 0.0257 0.0023 0.0023
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0287 0.0054 0.0662
Brugia malayi RhoGAP domain containing protein 0.0519 0.0296 0.0296
Brugia malayi serine/threonine protein kinase 6 0.0866 0.0657 0.0657
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.149 0.1306 0.1305
Onchocerca volvulus 0.0683 0.0466 0.1092
Echinococcus multilocularis casein kinase I alpha 0.0305 0.0073 0.0072
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Onchocerca volvulus 0.0323 0.0092 0.0215
Plasmodium falciparum protein kinase 5 0.0328 0.0097 0.1262
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0287 0.0054 0.0054
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0287 0.0054 0.0662
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0568 0.0347 0.0338
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0586 0.0365 0.0365
Brugia malayi hypothetical protein 0.067 0.0453 0.0453
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Trichomonas vaginalis CMGC family protein kinase 0.0262 0.0028 0.026
Schistosoma mansoni titin 0.0336 0.0105 0.0096
Entamoeba histolytica casein kinase, putative 0.0285 0.0053 0.0522
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0235 0.0001 0.0001
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0704 0.0488 0.0488
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1177 0.0979 0.0979
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1415 0.1228 0.1228
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Trypanosoma brucei casein kinase I, isoform 2 0.0305 0.0073 0.0564
Toxoplasma gondii AGC kinase 0.0655 0.0437 0.6095
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.052 0.0297 0.0297
Echinococcus granulosus tyrosine protein kinase Src42A 0.0906 0.0698 0.0697
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0404 0.0176 0.0176
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.145 0.1264 0.1263
Schistosoma mansoni hypothetical protein 0.1271 0.1078 0.107
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0363 0.0134 0.1789
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0248 0.0014 0.0014
Echinococcus granulosus Protein kinase C brain isozyme 0.0909 0.0702 0.0701
Entamoeba histolytica tyrosin kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Schistosoma mansoni SH2A 0.036 0.013 0.0122
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0315 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0336 0.0105 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0656 0.0439 0.043
Echinococcus granulosus SH2 motif 0.036 0.013 0.013
Entamoeba histolytica serine/threonine kinase, putative 0.0323 0.0092 0.0914
Entamoeba histolytica serine/threonine kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0495 0.0271 0.0271
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0276 0.0043 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni protein kinase 0.0456 0.0231 0.0222
Toxoplasma gondii histone kinase SNF1, putative 0.0453 0.0227 0.3114
Echinococcus multilocularis casein kinase ii subunit alpha 0.0285 0.0053 0.0052
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0287 0.0054 0.0662
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0655 0.0437 0.6095
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0268 0.0035 0.0034
Brugia malayi SH2 domain containing protein 0.1369 0.1179 0.1179
Plasmodium vivax protein kinase Crk2 0.0328 0.0097 0.1262
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0757 0.0543 0.0543
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0658 0.044 0.0439
Loa Loa (eye worm) TK/CSK protein kinase 0.0323 0.0092 0.0092
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0919 0.0712 1
Entamoeba histolytica protein kinase domain containing protein 0.0757 0.0543 0.5433
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1369 0.1179 0.1179
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) TK/KIN16 protein kinase 0.4904 0.4856 0.4856
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus multilocularis FL cytokine receptor 0.0323 0.0092 0.0091
Echinococcus multilocularis transfer RNA-Phe 0.0271 0.0038 0.0037
Echinococcus granulosus Glutaredoxin protein 5 0.0257 0.0023 0.0023
Echinococcus granulosus tyrosine protein kinase 0.2903 0.2775 0.2774
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0517 0.0294 0.0294
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0323 0.0092 0.1105
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0757 0.0543 0.4978
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis CMGC family protein kinase 0.0328 0.0097 0.1169
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1563 0.1381 0.1381
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0391 0.0162 0.2191
Echinococcus granulosus SHC transforming protein 3 0.036 0.013 0.013
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0547 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.067 0.0453 0.0453
Schistosoma mansoni protein kinase 0.0638 0.0419 0.0411
Entamoeba histolytica protein kinase, putative 0.029 0.0057 0.0569
Brugia malayi Protein kinase domain containing protein 0.0673 0.0456 0.0456
Echinococcus multilocularis cyclin dependent kinase 19 0.0404 0.0176 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Brugia malayi ephrin receptor 1 precursor 0.0391 0.0163 0.0163
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Entamoeba histolytica protein kinase, putative 0.1195 0.0999 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0287 0.0054 0.0662
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0248 0.0014 0.0014
Brugia malayi hypothetical protein 0.0323 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0906 0.0698 0.0697
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0071 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni cell adhesion molecule 0.0271 0.0038 0.0029
Leishmania major casein kinase, putative 0.0305 0.0073 0.0609
Schistosoma mansoni septate junction protein 0.0336 0.0105 0.0096
Echinococcus multilocularis activated cdc42 kinase 1 0.0323 0.0092 0.0091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0336 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0323 0.0092 0.0083
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0453 0.0227 0.2013
Brugia malayi Protein kinase domain containing protein 0.0562 0.034 0.034
Loa Loa (eye worm) STAT protein 0.036 0.013 0.013
Entamoeba histolytica protein kinase domain containing protein 0.0866 0.0657 0.6573
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0287 0.0054 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0655 0.0437 0.0428
Schistosoma mansoni serine/threonine protein kinase 0.0909 0.0702 0.0693
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Entamoeba histolytica protein kinase, putative 0.0866 0.0657 0.6573
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0438 0.0211 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Trypanosoma cruzi casein kinase, putative 0.0305 0.0073 0.0564
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis CMGC family protein kinase 0.0757 0.0543 0.7115
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0391 0.0162 0.1403
Echinococcus multilocularis epidermal growth factor receptor 0.9852 1 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0287 0.0054 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0227 0.0218
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0391 0.0162 0.0162
Entamoeba histolytica PH domain containing protein kinase, putative 0.0705 0.0489 0.4893
Echinococcus multilocularis SH2 domain containing adapter protein F 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Giardia lamblia Kinase, NEK 0.0323 0.0092 0.0961
Brugia malayi Sex muscle abnormal protein 5 0.0586 0.0365 0.0365
Echinococcus granulosus tyrosine protein kinase HCK 0.0864 0.0655 0.0654
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0404 0.0177 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0271 0.0038 0.0038
Brugia malayi Protein kinase domain containing protein 0.2869 0.2739 0.2739
Echinococcus multilocularis suppressor of cytokine signaling 7 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0336 0.0105 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0866 0.0657 0.0648
Toxoplasma gondii CMGC kinase, CK2 family 0.0285 0.0053 0.0638
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) hypothetical protein 0.067 0.0453 0.0453
Brugia malayi Raf kinase 0.0323 0.0092 0.0092
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0287 0.0054 0.0054
Echinococcus granulosus phosphorylase kinase gamma subunit 0.043 0.0203 0.0203
Echinococcus granulosus nephrin 0.0271 0.0038 0.0037
Schistosoma mansoni tyrosine kinase 0.0323 0.0092 0.0083
Trypanosoma cruzi polo-like protein kinase, putative 0.0617 0.0398 0.3619
Trypanosoma brucei protein kinase, putative 0.0757 0.0543 0.4978
Echinococcus multilocularis TGF beta receptor type 1 0.0744 0.0529 0.0529
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0092 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Onchocerca volvulus 0.0757 0.0543 0.1272
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Loa Loa (eye worm) CAMK/PHK protein kinase 0.043 0.0203 0.0203
Echinococcus multilocularis dual specificity 0.1195 0.0999 0.0998
Onchocerca volvulus 0.0323 0.0092 0.0215
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.149 0.1306 0.1298
Schistosoma mansoni atypical protein kinase C 0.1018 0.0815 0.0806
Brugia malayi P38 map kinase family protein 2 0.0419 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0337 0.0107 0.0107
Giardia lamblia Kinase, STE STE20 0.069 0.0473 0.5595
Echinococcus granulosus tyrosine protein kinase Src64B 0.145 0.1264 0.1263
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Onchocerca volvulus 0.036 0.013 0.0305
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1136 0.0937 0.0937
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus granulosus tensin C1 domain containing phosphatase 0.036 0.013 0.013
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.069 0.0473 0.4325
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis 0.4096 0.4015 0.4015
Schistosoma mansoni roundabout 0.0336 0.0105 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Entamoeba histolytica protein kinase domain containing protein 0.0354 0.0124 0.1234
Echinococcus granulosus cyclin dependent kinase 0.0328 0.0097 0.0096
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1089 0.0888 0.8878
Schistosoma mansoni tyrosine kinase 0.145 0.1264 0.1256
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0247 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0336 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.1271 0.1078 0.1078
Loa Loa (eye worm) hypothetical protein 0.067 0.0453 0.0453
Entamoeba histolytica receptor protein kinase, putative 0.0323 0.0092 0.0914
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) RGC/RGC protein kinase 0.0323 0.0092 0.0092
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0367 0.0137 0.1841
Trichomonas vaginalis AGC family protein kinase 0.0866 0.0657 0.8632
Onchocerca volvulus 0.0271 0.0038 0.0089
Brugia malayi putative serine/threonine kinase SADA gamma 0.0453 0.0227 0.0227
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0336 0.0105 0.0246
Onchocerca volvulus 0.0362 0.0132 0.031
Schistosoma mansoni septate junction protein 0.0336 0.0105 0.0096
Loa Loa (eye worm) AGC/PKN protein kinase 0.2326 0.2175 0.2175
Schistosoma mansoni cell adhesion molecule 0.0438 0.0211 0.0202
Echinococcus multilocularis serine:threonine protein kinase N2 0.2326 0.2175 0.2174
Onchocerca volvulus 0.0305 0.0073 0.0171
Loa Loa (eye worm) AUR protein kinase 0.0866 0.0657 0.0657
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0084 0.0997
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Entamoeba histolytica protein kinase, putative 0.0864 0.0655 0.6553
Schistosoma mansoni serine/threonine protein kinase 0.2771 0.2638 0.2631
Brugia malayi Protein kinase domain containing protein 0.1195 0.0999 0.0999
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1563 0.1381 0.1381
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0028 0.0019
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1195 0.0999 0.9259
Schistosoma mansoni tyrosine kinase 0.0909 0.0701 0.0693
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0453 0.0227 0.0227
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.3794 0.3701 0.3701
Echinococcus granulosus c-Jun N-terminal kinases 0.0656 0.0439 0.0438
Entamoeba histolytica protein kinase, putative 0.0237 0.0002 0.0016
Loa Loa (eye worm) TK/INSR protein kinase 0.6373 0.6383 0.6383
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0323 0.0092 0.0092
Onchocerca volvulus 0.0683 0.0466 0.1092
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0323 0.0092 0.0091
Echinococcus granulosus defective proboscis extension response 0.0568 0.0347 0.0346
Schistosoma mansoni tyrosine kinase 0.6953 0.6986 0.6983
Brugia malayi protein C17H12.11 0.052 0.0297 0.0297
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0419 0.0191 0.0191
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0438 0.0211 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0323 0.0092 0.1105
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.036 0.013 0.013
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus granulosus roundabout 2 0.0438 0.0211 0.021
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1059 0.0857 0.0857
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.036 0.013 0.0305
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus granulosus casein kinase I alpha 0.0305 0.0073 0.0072
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0521 0.0298 0.0297
Entamoeba histolytica cell division protein kinase 2, putative 0.0328 0.0097 0.0962
Echinococcus multilocularis 0.0786 0.0573 0.0572
Giardia lamblia Kinase, NEK 0.0367 0.0137 0.1514
Loa Loa (eye worm) hypothetical protein 0.0271 0.0038 0.0038
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Entamoeba histolytica protein kinase, putative 0.0915 0.0707 0.708
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Echinococcus multilocularis nervana 2 0.0257 0.0023 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Schistosoma mansoni hypothetical protein 0.0271 0.0038 0.0029
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0638 0.0419 0.0419
Echinococcus multilocularis MAM 0.0305 0.0073 0.0072
Echinococcus granulosus mitogen activated protein kinase 14 0.0419 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0438 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0287 0.0054 0.0054
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0919 0.0712 0.6565
Entamoeba histolytica hypothetical protein 0.0323 0.0092 0.0914
Plasmodium falciparum tyrosine kinase-like protein 0.0323 0.0092 0.1193
Echinococcus granulosus c src tyrosine kinase 0.0909 0.0701 0.0701
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1673 0.1496 0.1495
Loa Loa (eye worm) hypothetical protein 0.1043 0.0841 0.0841
Schistosoma mansoni serine/threonine protein kinase 0.0658 0.044 0.0432
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1673 0.1496 0.1495
Entamoeba histolytica cell division protein kinase 2, putative 0.0328 0.0097 0.0962
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0904 0.0696 0.0696
Trypanosoma brucei cdc2-related kinase 1 0.0328 0.0097 0.0788
Echinococcus granulosus nervana 2 0.0257 0.0023 0.0023
Echinococcus multilocularis insulin receptor 0.6373 0.6383 0.6383
Loa Loa (eye worm) TK protein kinase 0.1224 0.1029 0.1029
Trichomonas vaginalis conserved hypothetical protein 0.0323 0.0092 0.1105
Brugia malayi Protein kinase c protein 2 0.0385 0.0157 0.0156
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0456 0.0231 0.2047
Echinococcus multilocularis tyrosine protein kinase HCK 0.0864 0.0655 0.0654
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Leishmania major protein kinase, putative 0.069 0.0473 0.4671
Schistosoma mansoni tyrosine kinase 0.6953 0.6986 0.6983
Echinococcus multilocularis tyrosine protein kinase pr2 0.0323 0.0092 0.0091
Trichomonas vaginalis STE family protein kinase 0.0404 0.0177 0.2235
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1404 0.1216 0.1216
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0856 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.041 0.0182 0.0182
Echinococcus granulosus MAP kinase activated protein kinase 2 0.095 0.0744 0.0743
Brugia malayi Protein kinase domain containing protein 0.0683 0.0466 0.0466
Brugia malayi Protein kinase domain containing protein 0.2903 0.2775 0.2774
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0655 0.0437 0.6095
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0744 0.0529 0.0529
Echinococcus multilocularis nervana 2 0.0257 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.043 0.0203 0.0203
Onchocerca volvulus 0.036 0.013 0.0305
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis cyclin dependent kinase 5 0.0328 0.0097 0.0096
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0919 0.0712 0.6565
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0753 0.0539 0.0539
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Toxoplasma gondii protein kinase domain-containing protein 0.0323 0.0092 0.1193
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0456 0.0231 0.3165
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Schistosoma mansoni protein kinase 0.0285 0.0053 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0073 0.0064
Schistosoma mansoni tensin 0.036 0.013 0.0122
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0456 0.0231 0.2305
Loa Loa (eye worm) hypothetical protein 0.1271 0.1078 0.1078
Entamoeba histolytica protein kinase domain containing protein 0.1195 0.0999 1
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0856 0.0646 0.1514
Entamoeba histolytica protein kinase, putative 0.0406 0.0178 0.1774
Echinococcus multilocularis tyrosine protein kinase Blk 0.1224 0.1029 0.1028
Giardia lamblia Kinase, AGC PKA 0.0391 0.0162 0.1814
Schistosoma mansoni vav2 0.0569 0.0348 0.0339
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0513 0.0289 0.0289
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0404 0.0177 0.0176
Loa Loa (eye worm) hypothetical protein 0.0336 0.0105 0.0105
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0856 0.0646 0.0646
Plasmodium vivax unspecified product 0.0285 0.0053 0.0638
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0866 0.0657 0.6573
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis hemicentin 1 0.0336 0.0105 0.0105
Brugia malayi cytokine inducible SH2-containing protein 5 0.036 0.013 0.013
Loa Loa (eye worm) SRC-1 0.145 0.1264 0.1264
Trypanosoma brucei rac serine-threonine kinase, putative 0.0965 0.0759 0.7011
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.6953 0.6986 0.6985
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Echinococcus granulosus hypothetical protein 0.036 0.013 0.013
Schistosoma mansoni protein kinase 0.0866 0.0657 0.0648
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1563 0.1381 0.1381
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0456 0.0231 0.2047
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0735 0.052 0.0519
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2771 0.2638 0.2638
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.145 0.1264 0.1263
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0753 0.0539 0.0539
Entamoeba histolytica serine/threonine kinase, putative 0.0323 0.0092 0.0914
Brugia malayi C-terminal src kinase protein 1 0.0323 0.0092 0.0092
Brugia malayi integrin-linked kinase 0.0323 0.0092 0.0092
Schistosoma mansoni cell adhesion molecule 0.0438 0.0211 0.0202
Echinococcus granulosus raf serine:threonine protein kinase 0.0482 0.0257 0.0257
Echinococcus multilocularis lachesin 0.0336 0.0105 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Echinococcus granulosus activated cdc42 kinase 1 0.0323 0.0092 0.0091
Entamoeba histolytica protein kinase, putative 0.0658 0.044 0.4403
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0336 0.0105 0.0105
Loa Loa (eye worm) TK protein kinase 0.0323 0.0092 0.0092
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Echinococcus granulosus roundabout 2 0.1006 0.0802 0.0801
Echinococcus multilocularis rac serine:threonine kinase 0.0441 0.0214 0.0214
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0243 0.0009 0.0009
Loa Loa (eye worm) TK/RYK protein kinase 0.0323 0.0092 0.0092
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0519 0.0296 0.0287
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Onchocerca volvulus 0.0323 0.0092 0.0215
Echinococcus multilocularis dual specificity protein kinase clk2 0.0919 0.0712 0.0711
Plasmodium vivax casein kinase 1, putative 0.0305 0.0073 0.0923
Trichomonas vaginalis CAMK family protein kinase 0.0317 0.0086 0.1022
Entamoeba histolytica protein kinase, putative 0.1195 0.0999 1
Echinococcus granulosus activin receptor type 0.3573 0.3471 0.3471
Schistosoma mansoni tensin 0.036 0.013 0.0122
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.1809 0.1637 0.1637
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0453 0.0227 0.2013
Brugia malayi Protein kinase domain containing protein 0.0404 0.0176 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0655 0.0437 0.0428
Schistosoma mansoni shc transforming protein 0.036 0.013 0.0122
Brugia malayi SRC-1 0.145 0.1264 0.1264
Leishmania major hypothetical protein, conserved 0.0323 0.0092 0.0802
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.104 0.0837 0.0837
Schistosoma mansoni serine/threonine protein kinase 0.0547 0.0325 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Plasmodium falciparum calcium-dependent protein kinase 3 0.0287 0.0054 0.0662
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Loa Loa (eye worm) hypothetical protein 0.036 0.013 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.0097 0.0088
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.082 0.0608 0.0608
Plasmodium falciparum casein kinase 1 0.0305 0.0073 0.0923
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Brugia malayi Protein kinase domain containing protein 0.0654 0.0436 0.0436
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus SH2 domain containing protein 7 0.036 0.013 0.013
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0315 0.0084 0.1078
Echinococcus multilocularis N chimaerin 0.0519 0.0296 0.0295
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0438 0.0211 0.0211
Echinococcus granulosus insulin receptor 0.6373 0.6383 0.6383
Echinococcus granulosus SH2 motif 0.036 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus granulosus casein kinase ii subunit alpha 0.0285 0.0053 0.0052
Echinococcus granulosus tyrosine protein kinase Src42A 0.145 0.1264 0.1263
Echinococcus granulosus casein kinase I alpha 0.0305 0.0073 0.0072
Entamoeba histolytica PH domain containing protein kinase, putative 0.0441 0.0214 0.214
Echinococcus granulosus mitogen activated protein kinase 0.0248 0.0014 0.0014
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0654 0.0436 0.0436
Trypanosoma cruzi Protein kinase B 0.0441 0.0214 0.1891
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1415 0.1228 0.1228
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0243 0.0009 0.0009
Entamoeba histolytica tyrosin kinase, putative 0.0354 0.0124 0.1234
Plasmodium vivax serine/threonine protein kinase, putative 0.0247 0.0013 0.007
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0257 0.0023 0.0023
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Echinococcus multilocularis SH2 domain containing protein 7 0.036 0.013 0.013
Echinococcus granulosus tyrosine protein kinase csk 0.0323 0.0092 0.0091
Echinococcus granulosus protein kinase c epsilon type 0.082 0.0608 0.0608
Trypanosoma cruzi casein kinase, putative 0.0305 0.0073 0.0564
Echinococcus multilocularis raf serine:threonine protein kinase 0.0482 0.0257 0.0257
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Brugia malayi serine/threonine kinase 12 0.0866 0.0657 0.0657
Echinococcus granulosus epidermal growth factor receptor 0.9852 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0617 0.0398 0.5186
Schistosoma mansoni serine/threonine protein kinase 0.0547 0.0325 0.0316
Trichomonas vaginalis AGC family protein kinase 0.0965 0.0759 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0438 0.0211 0.0211
Loa Loa (eye worm) IKK protein kinase 0.0673 0.0456 0.0456
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Brugia malayi protein-tyrosine kinase 0.1224 0.1029 0.1029
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0323 0.0092 0.0083
Schistosoma mansoni serine/threonine kinase 0.0549 0.0327 0.0319
Giardia lamblia Kinase, CMGC GSK 0.0757 0.0543 0.6439
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0248 0.0014 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0517 0.0294 0.2936
Loa Loa (eye worm) hypothetical protein 0.0269 0.0036 0.0036
Schistosoma mansoni tyrosine kinase 0.262 0.2481 0.2474
Brugia malayi Variant SH3 domain containing protein 0.0519 0.0296 0.0296
Echinococcus multilocularis tyrosine protein kinase csk 0.0323 0.0092 0.0091
Echinococcus multilocularis roundabout 2 0.0438 0.0211 0.021
Schistosoma mansoni titin 0.0405 0.0177 0.0168
Trichomonas vaginalis AGC family protein kinase 0.0704 0.0488 0.6386
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0571 0.035 0.035
Echinococcus granulosus neuroglian 0.0737 0.0523 0.0522
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0257 0.0023 0.0023
Onchocerca volvulus 0.0314 0.0082 0.0193
Echinococcus multilocularis tyrosine protein kinase Fyn 0.145 0.1264 0.1263
Schistosoma mansoni hypothetical protein 0.0305 0.0073 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.6051 0.6048 0.6048
Entamoeba histolytica hypothetical protein 0.0859 0.0649 0.65
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0328 0.0097 0.0097
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.104 0.0837 0.0837
Toxoplasma gondii AGC kinase 0.0915 0.0707 0.9935
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Schistosoma mansoni tyrosine kinase 0.663 0.665 0.6647
Loa Loa (eye worm) hypothetical protein 0.0271 0.0038 0.0038
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0336 0.0105 0.0105
Loa Loa (eye worm) SH2 domain-containing protein 0.036 0.013 0.013
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0453 0.0227 0.2174
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0404 0.0177 0.0176
Brugia malayi Variant SH3 domain containing protein 0.0413 0.0185 0.0185
Echinococcus multilocularis casein kinase I alpha 0.0305 0.0073 0.0072
Onchocerca volvulus 0.1002 0.0798 0.187
Trichomonas vaginalis CK1 family protein kinase 0.0305 0.0073 0.0851
Loa Loa (eye worm) hypothetical protein 0.0305 0.0073 0.0073
Leishmania major protein kinase A catalytic subunit isoform 1 0.0655 0.0437 0.4302
Loa Loa (eye worm) AUR protein kinase 0.0866 0.0657 0.0657
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1195 0.0999 0.9259
Trichomonas vaginalis CAMK family protein kinase 0.0345 0.0114 0.1407
Echinococcus granulosus NCK adaptor protein 0.0586 0.0365 0.0365
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0248 0.0014 0.0014
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0404 0.0177 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Loa Loa (eye worm) TK protein kinase 0.0864 0.0655 0.0655
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0287 0.0054 0.0054
Onchocerca volvulus 0.1271 0.1078 0.2525
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0405 0.0177 0.0177
Schistosoma mansoni protein kinase C mu 0.1136 0.0937 0.0929
Echinococcus multilocularis expressed conserved protein 0.0363 0.0134 0.0133
Loa Loa (eye worm) hypothetical protein 0.0683 0.0466 0.0466
Plasmodium falciparum protein serine/threonine kinase-1 0.0919 0.0712 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Brugia malayi Doublecortin family protein 0.04 0.0172 0.0172
Echinococcus granulosus contactin 0.0438 0.0211 0.021
Trichomonas vaginalis CMGC family protein kinase 0.0248 0.0014 0.0071
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Brugia malayi Protein kinase domain containing protein 0.0683 0.0466 0.0466
Brugia malayi serine/threonine-protein kinase 6 0.0866 0.0657 0.0657
Entamoeba histolytica protein kinase, putative 0.0247 0.0013 0.0122
Brugia malayi Receptor family ligand binding region containing protein 0.0323 0.0092 0.0092
Brugia malayi Egg laying defective protein 4 0.0363 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.2946 0.282 0.2819
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0323 0.0092 0.1193
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0909 0.0701 0.0693
Leishmania major protein kinase, putative 0.0919 0.0712 0.7091
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0655 0.0437 0.0436
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0419 0.0191 0.1678
Onchocerca volvulus 0.036 0.013 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0227 0.2908
Entamoeba histolytica protein kinase, putative 0.0324 0.0093 0.0928
Onchocerca volvulus 0.0235 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Echinococcus multilocularis serine:threonine protein kinase N2 0.1668 0.1491 0.149
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Echinococcus granulosus retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0541 0.0319 0.031
Loa Loa (eye worm) hypothetical protein 0.0843 0.0633 0.0633
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Entamoeba histolytica serine/threonine protein kinase, putative 0.0453 0.0227 0.2269
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Brugia malayi Immunoglobulin I-set domain containing protein 0.067 0.0453 0.0453
Schistosoma mansoni kinase 0.0537 0.0314 0.0306
Echinococcus multilocularis protein kinase c epsilon type 0.082 0.0608 0.0608
Trichomonas vaginalis CMGC family protein kinase 0.0285 0.0053 0.0584
Echinococcus granulosus lachesin 0.0336 0.0105 0.0105
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0757 0.0543 0.5376
Onchocerca volvulus 0.0683 0.0466 0.1092
Echinococcus granulosus retinal guanylyl cyclase 2 0.0323 0.0092 0.0091
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0305 0.0073 0.0073
Schistosoma mansoni protein kinase 0.0404 0.0177 0.0168
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0317 0.0086 0.0086
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0494 0.0269 0.0269
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.3794 0.3701 0.3701
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica p21-activated kinase 0.0455 0.0229 0.2285
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Schistosoma mansoni ephrin receptor 0.0425 0.0198 0.0189
Trichomonas vaginalis STE family protein kinase 0.0404 0.0177 0.2235
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0323 0.0092 0.0083
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.043 0.0203 0.0203
Schistosoma mansoni protein kinase 0.0323 0.0092 0.0083
Echinococcus multilocularis mitogen activated protein kinase 11 0.0419 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0317 0.0086 0.0086
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0549 0.0327 0.0327
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0323 0.0092 0.0091
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0517 0.0294 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0919 0.0712 0.0704
Schistosoma mansoni titin 0.0271 0.0038 0.0029
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0856 0.0646 0.0646
Echinococcus multilocularis kinase suppressor of Ras 1 0.0323 0.0092 0.0091
Echinococcus multilocularis cyclin dependent kinase 0.0328 0.0097 0.0096
Schistosoma mansoni rap gtpase-activating protein 0.1271 0.1078 0.107
Trichomonas vaginalis CK1 family protein kinase 0.0305 0.0073 0.0851
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0038 0.0038
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0323 0.0092 0.1105
Brugia malayi SH2 domain containing protein 0.036 0.013 0.013
Entamoeba histolytica hypothetical protein 0.1195 0.0999 1
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.0092 0.1105
Loa Loa (eye worm) hypothetical protein 0.0473 0.0248 0.0248
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0441 0.0214 0.1891
Entamoeba histolytica tyrosin kinase, putative 0.0323 0.0092 0.0914
Loa Loa (eye worm) AUR protein kinase 0.0866 0.0657 0.0657
Giardia lamblia Aurora kinase 0.0866 0.0657 0.7822
Echinococcus granulosus casein kinase i 0.0305 0.0073 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Brugia malayi Protein kinase domain containing protein 0.063 0.0411 0.0411
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Echinococcus granulosus natriuretic peptide receptor 1 0.0323 0.0092 0.0091
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0655 0.0437 0.3983
Giardia lamblia Kinase, CAMK CAMKL 0.0453 0.0227 0.2604
Leishmania major protein kinase, putative 0.0287 0.0054 0.0423
Brugia malayi Guanylyl cyclase protein 23 0.0323 0.0092 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.0084 0.0075
Brugia malayi Casein kinase II, alpha chain 0.0285 0.0053 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.095 0.0744 0.0736
Trichomonas vaginalis TKL family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis integrin linked protein kinase 0.0323 0.0092 0.0091
Echinococcus granulosus cGMP dependent protein kinase 1 0.0363 0.0134 0.0133
Brugia malayi hypothetical protein 0.0683 0.0466 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0517 0.0294 0.0285
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0327 0.0097 0.0096
Loa Loa (eye worm) hypothetical protein 0.0904 0.0696 0.0696
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0757 0.0543 0.7599
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0323 0.0092 0.0914
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0492 0.0268 0.0267
Echinococcus multilocularis dual specificity 0.0315 0.0084 0.0083
Echinococcus multilocularis protein kinase shaggy 0.0757 0.0543 0.0542
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0517 0.0294 0.0294
Entamoeba histolytica tyrosine kinase, putative 0.0323 0.0092 0.0914
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0757 0.0543 0.0542
Entamoeba histolytica protein kinase 2, putative 0.0391 0.0162 0.1618
Loa Loa (eye worm) hypothetical protein 0.0323 0.0092 0.0092
Echinococcus granulosus serine:threonine protein kinase N2 0.1668 0.1491 0.149
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0419 0.0191 0.1678
Brugia malayi Stress-activated protein kinase jnk-1 0.0656 0.0439 0.0439
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0336 0.0105 0.0096
Entamoeba histolytica protein kinase, putative 0.0247 0.0013 0.0122
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0866 0.0657 0.9216
Echinococcus multilocularis mitogen activated protein kinase 0.0248 0.0014 0.0014
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0276 0.0043 0.0042
Trichomonas vaginalis STE family protein kinase 0.0323 0.0092 0.1105
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0243 0.0009 0.0008
Brugia malayi serine/threonine-protein kinase plk-2 0.0617 0.0398 0.0398
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0084 0.0997
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0915 0.0707 0.0707
Loa Loa (eye worm) TK/FER protein kinase 0.0323 0.0092 0.0092
Entamoeba histolytica cysteine surface protein, putative 0.0323 0.0092 0.0914
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0519 0.0296 0.0287
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Onchocerca volvulus 0.2036 0.1873 0.4388
Echinococcus multilocularis tyrosine protein kinase shark 0.298 0.2855 0.2855
Brugia malayi Protein kinase domain containing protein 0.444 0.4372 0.4372
Echinococcus multilocularis dual specificity 0.0315 0.0084 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0092 0.0914
Loa Loa (eye worm) hypothetical protein 0.0271 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0453 0.0227 0.0227
Trichomonas vaginalis CMGC family protein kinase 0.0248 0.0014 0.0071
Schistosoma mansoni tensin-related 0.036 0.013 0.0122
Brugia malayi Protein kinase domain containing protein 0.0323 0.0092 0.0092
Echinococcus granulosus kinase suppressor of Ras 1 0.0323 0.0092 0.0091
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0323 0.0092 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.0658 0.044 0.0432
Brugia malayi Protein kinase domain containing protein 0.0317 0.0086 0.0086
Echinococcus multilocularis c src tyrosine kinase 0.0909 0.0701 0.0701
Plasmodium falciparum casein kinase 2, alpha subunit 0.0285 0.0053 0.0638
Echinococcus multilocularis serine:threonine protein kinase 0.0317 0.0086 0.0085
Trypanosoma brucei SNF1-related protein kinases, putative 0.0453 0.0227 0.2013
Echinococcus multilocularis Immunoglobulin 0.0568 0.0347 0.0346
Entamoeba histolytica casein kinase 1, putative 0.0305 0.0073 0.0724
Entamoeba histolytica protein kinase, putative 0.0323 0.0092 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.0134 0.0125
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0757 0.0543 0.0534

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8.3 nM Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassay ChEMBL. 19358611
IC50 (binding) = 167 nM Inhibition of human recombinant rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassay ChEMBL. 19358611

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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