Detailed information for compound 977509

Basic information

Technical information
  • TDR Targets ID: 977509
  • Name: (5R,5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxy-ph enyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-isobe nzofurano[5,6-f][1,3]benzodioxol-8-one
  • MW: 386.352 | Formula: C20H18O8
  • H donors: 3 H acceptors: 4 LogP: 1.52 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(cc(c1O)O)[C@H]1[C@H]2C(=O)OC[C@@H]2[C@H](c2c1cc1OCOc1c2)O
  • InChi: 1S/C20H18O8/c1-25-15-3-8(2-12(21)19(15)23)16-9-4-13-14(28-7-27-13)5-10(9)18(22)11-6-26-20(24)17(11)16/h2-5,11,16-18,21-23H,6-7H2,1H3/t11-,16+,17-,18-/m0/s1
  • InChiKey: UCILNJOMIKDJGF-MJQACMKBSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (5R,5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxyphenyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tubulin beta chain 0.0052 0.0448 0.0579
Trichomonas vaginalis tubulin alpha chain, putative 0.0165 0.1775 0.2293
Trichomonas vaginalis tubulin, putative 0.0052 0.0448 0.0579
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0084 0.0084
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Echinococcus multilocularis cpg binding protein 0.0032 0.0225 0.0225
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0026 0.0146 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0027 0.0163 0.2855
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Loa Loa (eye worm) tubulin alpha chain 0.0144 0.1536 0.1985
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0674 0.774 1
Giardia lamblia Delta tubulin 0.0052 0.0448 0.0553
Echinococcus granulosus intermediate filament protein 0.0057 0.0509 0.06
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0068 0.0637 0.0824
Loa Loa (eye worm) tubulin alpha 2 0.0093 0.0932 0.1204
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0229 0.0296
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.1059 0.1369
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Schistosoma mansoni tubulin subunit beta 0.0052 0.0448 0.0528
Loa Loa (eye worm) tubulin beta chain 0.0052 0.0448 0.0579
Loa Loa (eye worm) tubulin beta-1 chain 0.0165 0.1775 0.2293
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.005 0.0065
Schistosoma mansoni tubulin subunit alpha 0.0052 0.0448 0.0528
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0009
Brugia malayi DNA polymerase family B containing protein 0.0015 0.0022 0.0028
Brugia malayi DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0377 0.0487
Trichomonas vaginalis tubulin, putative 0.0067 0.0631 0.0816
Trypanosoma brucei epsilon tubulin 0.0119 0.1235 0.158
Loa Loa (eye worm) tubulin alpha chain 0.0144 0.1536 0.1985
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0081 0.0105
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.0653 0.0653
Echinococcus multilocularis GPCR, family 2 0.0033 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0027 0.0165 0.0213
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0024 0.0029
Loa Loa (eye worm) hypothetical protein 0.0104 0.1059 0.1369
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Plasmodium vivax vivapain-2 0.002 0.0073 0.0094
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0674 0.774 1
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0084 0.01
Echinococcus multilocularis Tubulin alpha 1 chain 0.0144 0.1536 0.1536
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.1206 0.1558
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0198
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Loa Loa (eye worm) phosphofructokinase 0.0116 0.1206 0.1558
Brugia malayi Death domain containing protein 0.0015 0.0024 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0163 0.0192
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0165 0.1773 0.1773
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Onchocerca volvulus 0.0042 0.0336 0.0434
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Brugia malayi glutathione reductase 0.0051 0.0437 0.0564
Plasmodium vivax tubulin gamma chain, putative 0.0119 0.1235 0.1596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.005 0.0064
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0212 0.0274
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.005 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0038 0.0049
Echinococcus granulosus Tubulin alpha 1 chain 0.0144 0.1536 0.181
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0026 0.0031
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.005 0.0195
Onchocerca volvulus 0.0165 0.1773 0.2291
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.016 0.0207
Trypanosoma cruzi zeta tubulin, putative 0.0052 0.0448 0.0561
Echinococcus multilocularis tubulin delta chain 0.0052 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0336 0.0415
Brugia malayi RNA binding protein 0.0132 0.1388 0.1794
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0293 0.0359
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0212 0.0274
Brugia malayi Thioredoxin reductase 0.0051 0.0437 0.0564
Schistosoma mansoni tubulin subunit delta 0.0052 0.0448 0.0528
Leishmania major delta tubulin, putative 0.0052 0.0448 0.0561
Loa Loa (eye worm) CYP4Cod1 0.0024 0.012 0.0155
Leishmania major hypothetical protein, conserved 0.0027 0.016 0.0187
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Loa Loa (eye worm) hypothetical protein 0.0093 0.0932 0.1204
Brugia malayi alpha-tubulin 0.0144 0.1536 0.1985
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0555 0.0717
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0084 0.0109
Entamoeba histolytica hypothetical protein 0.0021 0.0084 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.1206 0.1541
Echinococcus multilocularis Chromobox protein 3 0.0013 0.00000004398 0.00000004398
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0055 0.0487 0.0574
Echinococcus multilocularis 0.0015 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0069 0.0653 0.0844
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Echinococcus multilocularis L aminoadipate semialdehyde 0.0097 0.0979 0.0979
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0198
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0027 0.0163 0.0843
Echinococcus granulosus neuropeptide s receptor 0.0539 0.6154 0.7251
Brugia malayi CHD4 protein 0.0015 0.0021 0.0026
Echinococcus multilocularis tubulin alpha 1C chain 0.0144 0.1536 0.1536
Trichomonas vaginalis esterase, putative 0.0042 0.0336 0.0434
Brugia malayi Pre-SET motif family protein 0.0069 0.0653 0.0844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0191
Echinococcus multilocularis tubulin alpha 0.0119 0.1235 0.1235
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0073 0.0086
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.0653 0.0769
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Schistosoma mansoni hypothetical protein 0.0056 0.0502 0.0592
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.005 0.0058
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Schistosoma mansoni alpha tubulin 0.0144 0.1536 0.181
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0084 0.0084
Echinococcus granulosus glycoprotein Antigen 5 0.0165 0.1773 0.2089
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.005 0.0064
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0024 0.0125 0.0142
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0336 0.0415
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Trypanosoma cruzi epsilon tubulin, putative 0.0119 0.1235 0.158
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0024 0.0029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii DNA polymerase 0.0015 0.0022 0.0028
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0674 0.774 0.774
Echinococcus multilocularis Mastin 0.0165 0.1773 0.1773
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Trichomonas vaginalis tubulin, putative 0.0067 0.0631 0.0816
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0015 0.0022 0.0026
Mycobacterium tuberculosis Probable oxidoreductase 0.0128 0.1346 0.1723
Trypanosoma brucei tubulin delta chain 0.0052 0.0448 0.0561
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0115 0.1195 0.1528
Schistosoma mansoni hypothetical protein 0.0082 0.0809 0.0954
Echinococcus granulosus 6 phosphofructokinase 0.0116 0.1206 0.1421
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0115 0.1195 0.1528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0181 0.0234
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.1418 0.1832
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0082 0.0809 0.0953
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0084 0.01
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0024 0.0032
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0336 0.0415
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0073 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0336 0.0415
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Onchocerca volvulus 0.002 0.0073 0.0094
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0084 0.01
Schistosoma mansoni tubulin subunit alpha 0.0144 0.1536 0.181
Treponema pallidum cell division protein FtsZ 0.0052 0.0448 0.0518
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0073 0.0094
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0407 0.0507
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0229 0.027
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Trichomonas vaginalis tubulin gamma chain, putative 0.0052 0.0448 0.0579
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0073 0.0094
Loa Loa (eye worm) RecQ helicase 0.0023 0.0112 0.0144
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0093 0.0932 0.1204
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0212 0.0274
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0493 0.0637
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0055 0.0487 0.0487
Plasmodium vivax tubulin alpha chain, putative 0.0144 0.1536 0.1985
Echinococcus multilocularis expressed protein 0.0399 0.4519 0.4519
Echinococcus multilocularis tubulin epsilon chain 0.0119 0.1235 0.1235
Echinococcus multilocularis neuropeptide s receptor 0.0539 0.6154 0.6154
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0024 0.0125 0.0142
Brugia malayi Uncoordinated protein 44 0.0015 0.0024 0.0032
Echinococcus granulosus tubulin subunit beta 0.0165 0.1775 0.2091
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.0229
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0128 0.1346 1
Leishmania major cathepsin L-like protease 0.0074 0.0715 0.0906
Onchocerca volvulus 0.0165 0.1773 0.2291
Echinococcus multilocularis 6 phosphofructokinase 0.0116 0.1206 0.1206
Schistosoma mansoni alpha tubulin 0.0144 0.1536 0.181
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0084 0.01
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0229 0.0296
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0715 0.0906
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0097 0.0979 0.1153
Echinococcus multilocularis tumor protein p63 0.0361 0.4076 0.4076
Loa Loa (eye worm) hypothetical protein 0.0143 0.1516 0.1959
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0015 0.0022 0.0028
Loa Loa (eye worm) TAR-binding protein 0.0132 0.1388 0.1794
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0097 0.0979 0.1265
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0116 0.1206 0.1503
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.000000000045487 0.000000000053597
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0407 0.048
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0027 0.0163 0.0192
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0674 0.774 0.912
Schistosoma mansoni hypothetical protein 0.0388 0.439 0.5172
Treponema pallidum ATP-dependent RNA helicase 0.0674 0.774 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Echinococcus multilocularis hypothetical protein 0.0144 0.1536 0.1536
Brugia malayi CXXC zinc finger family protein 0.0031 0.0204 0.0264
Schistosoma mansoni hypothetical protein 0.0018 0.005 0.0059
Loa Loa (eye worm) tubulin beta-2A chain 0.0165 0.1775 0.2293
Trypanosoma cruzi epsilon tubulin, putative 0.0119 0.1235 0.158
Brugia malayi PXA domain containing protein 0.0021 0.0084 0.0109
Echinococcus multilocularis tubulin beta 1 chain 0.0165 0.1775 0.1775
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0052 0.0448 0.0579
Brugia malayi intermediate filament protein 0.0057 0.0509 0.0658
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0082 0.0809 0.0954
Brugia malayi Pre-SET motif family protein 0.0477 0.5435 0.7022
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0015 0.0022 0.0026
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.012 0.0155
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Loa Loa (eye worm) RNA binding protein 0.0132 0.1388 0.1794
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0222 0.0286
Brugia malayi chromobox protein homolog 3 0.0046 0.0377 0.0487
Echinococcus granulosus beta tubulin 0.0165 0.1775 0.2091
Mycobacterium tuberculosis Conserved protein 0.0042 0.0336 0.0415
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0084 0.0084
Brugia malayi Trypsin-like protease protein 5 0.0165 0.1773 0.2291
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0674 0.774 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.000000000045487 0.000000000058772
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0084 0.0084
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0015 0.0022 0.0028
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0021 0.0024
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0631 0.0816
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0112 0.0144
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0163 0.0211
Brugia malayi hypothetical protein 0.0082 0.0809 0.1046
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.005 0.005
Trichomonas vaginalis tubulin epsilon chain, putative 0.0165 0.1775 0.2293
Schistosoma mansoni transcription factor LCR-F1 0.0082 0.0809 0.0954
Loa Loa (eye worm) hypothetical protein 0.0674 0.774 1
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Brugia malayi MH2 domain containing protein 0.0134 0.1418 0.1832
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0112 0.0112
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0073 0.0086
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0407 0.0507
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0084 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus granulosus geminin 0.0388 0.439 0.5172
Brugia malayi hypothetical protein 0.0162 0.1737 0.2244
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0407 0.0526
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0065
Schistosoma mansoni tubulin subunit gamma 0.0119 0.1235 0.1456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.016 0.0207
Brugia malayi PXA domain containing protein 0.0021 0.0084 0.0109
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0033 0.0023
Schistosoma mansoni alpha tubulin 0.0144 0.1536 0.181
Leishmania major eukaryotic initiation factor 4a, putative 0.0674 0.774 1
Loa Loa (eye worm) cysteine protease 0.002 0.0073 0.0094
Onchocerca volvulus 0.002 0.0073 0.0094
Brugia malayi Cytochrome P450 family protein 0.0015 0.0015 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.016 0.0187
Plasmodium vivax tubulin alpha chain, putative 0.0144 0.1536 0.1985
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0084 0.01
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0032
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0073 0.0073
Giardia lamblia Alpha-tubulin 0.0144 0.1536 0.1962
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0073 0.0073
Brugia malayi tubulin alpha-2 chain 0.0144 0.1536 0.1985
Echinococcus multilocularis cysteine protease 0.002 0.0073 0.0073
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0075 0.0727 0.094
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0165 0.1773 0.2089
Mycobacterium tuberculosis Conserved protein 0.0042 0.0336 0.0415
Leishmania major hypothetical protein, conserved 0.0042 0.0336 0.0415
Brugia malayi 6-phosphofructokinase 0.0116 0.1206 0.1558
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0015 0.0018
Mycobacterium ulcerans hypothetical protein 0.0165 0.1773 1
Brugia malayi laminin-like protein K08C7.3 precursor 0.0026 0.0146 0.0188
Echinococcus multilocularis tubulin subunit beta 0.0165 0.1775 0.1775
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0163 0.0211
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0509 0.0658
Echinococcus granulosus neuropeptide receptor A26 0.0539 0.6154 0.7251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0212 0.0274
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0084 0.0109
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0068 0.0637 0.0751
Loa Loa (eye worm) tubulin beta chain 0.0165 0.1775 0.2293
Mycobacterium ulcerans hypothetical protein 0.0042 0.0336 0.1823
Entamoeba histolytica hypothetical protein 0.0027 0.0163 0.0211
Brugia malayi 6-phosphofructokinase 0.0116 0.1206 0.1558
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0165 0.1773 0.2089
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0024 0.0029
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0084 0.0109
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0073 0.0094
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0015 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.02 0.0259
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0115 0.1195 0.1528
Schistosoma mansoni chromobox protein 0.0081 0.0795 0.0937
Echinococcus granulosus chromobox protein 1 0.0081 0.0795 0.0937
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Echinococcus granulosus chromobox protein 1 0.0081 0.0795 0.0937
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.3071 0.3618
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0407 0.0526
Brugia malayi Protein kinase domain containing protein 0.0015 0.0024 0.0032
Leishmania major cysteine peptidase A (CPA) 0.002 0.0073 0.0075
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0084 0.01
Echinococcus granulosus Tubulin alpha 1 chain 0.0144 0.1536 0.181
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.1388 0.1794
Onchocerca volvulus 0.0057 0.0509 0.0658
Trypanosoma brucei epsilon tubulin 0.0119 0.1235 0.158
Loa Loa (eye worm) tubulin alpha-3 chain 0.0077 0.0749 0.0968
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0028
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0204 0.0264
Onchocerca volvulus 0.0499 0.5682 0.7342
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Echinococcus multilocularis chromobox protein 1 0.0081 0.0795 0.0795
Loa Loa (eye worm) hypothetical protein 0.0276 0.3071 0.3967
Echinococcus multilocularis tubulin alpha 1C chain 0.0144 0.1536 0.1536
Onchocerca volvulus 0.0036 0.0262 0.0339
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0212 0.0274
Loa Loa (eye worm) hypothetical protein 0.0033 0.0229 0.0296
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0077 0.0749 0.0968
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.0637 0.0751
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Loa Loa (eye worm) runx1 0.0063 0.0577 0.0745
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Plasmodium falciparum alpha tubulin 2 0.0144 0.1536 0.1985
Loa Loa (eye worm) BEN-1 protein 0.0165 0.1775 0.2293
Leishmania major cathepsin L-like protease 0.0074 0.0715 0.0906
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.005 0.0044
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0128 0.1346 0.1723
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.000000000045487 0.000000000058772
Schistosoma mansoni cytochrome P450 0.0015 0.0015 0.0018
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0336 0.0415
Brugia malayi Tubulin alpha chain 0.0052 0.0448 0.0579
Schistosoma mansoni cell polarity protein 0.0026 0.0146 0.0172
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0033 0.0043
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0084 0.0084
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0146 0.0172
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0033 0.0043
Trypanosoma cruzi beta tubulin, putative 0.0165 0.1775 0.2278
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0084 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0021 0.0085 0.01
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0336 0.0395
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0212 1
Onchocerca volvulus 0.002 0.0073 0.0094
Echinococcus multilocularis tubulin alpha 3 chain 0.0144 0.1536 0.1536
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Brugia malayi isocitrate dehydrogenase 0.0033 0.0229 0.0296
Toxoplasma gondii alpha tubulin TUBA1 0.0144 0.1536 0.1985
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0073 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.005 0.0044
Onchocerca volvulus Cathepsin F homolog 0.002 0.0073 0.0094
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0067 0.0631 0.0816
Schistosoma mansoni hypothetical protein 0.0388 0.439 0.5172
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.016 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Onchocerca volvulus Huntingtin homolog 0.0143 0.1516 0.1959
Echinococcus granulosus bloom syndrome protein 0.0023 0.0112 0.0132
Trichomonas vaginalis tubulin beta chain, putative 0.0067 0.0631 0.0816
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0653 0.0769
Plasmodium vivax delta tubulin, putative 0.0052 0.0448 0.0579
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0212 0.0274
Plasmodium falciparum tubulin epsilon chain, putative 0.0119 0.1235 0.1596
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0021 0.0024
Trichomonas vaginalis DNA polymerase II, putative 0.0024 0.0125 0.0161
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0116 0.1206 0.8946
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0181 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0068 0.0639 0.0808
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0407 0.0507
Trypanosoma cruzi tubulin gamma chain 0.0119 0.1235 0.158
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Brugia malayi hypothetical protein 0.0021 0.0084 0.0109
Brugia malayi hypothetical protein 0.0017 0.0048 0.0062
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0477 0.5435 0.7022
Brugia malayi hypothetical protein 0.0021 0.0084 0.0109
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0119 0.1235 0.1596
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0018
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.1206 0.1558
Loa Loa (eye worm) hypothetical protein 0.0144 0.1536 0.1985
Loa Loa (eye worm) beta-lactamase 0.0042 0.0336 0.0434
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Trypanosoma cruzi alpha tubulin, putative 0.0144 0.1536 0.1969
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0336 0.1823
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.005 0.0064
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0084 0.0109
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Toxoplasma gondii ABC1 family protein 0.0042 0.0336 0.0434
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0674 0.774 1
Echinococcus granulosus Ankyrin 0.0016 0.0026 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Trichomonas vaginalis tubulin epsilon chain, putative 0.0144 0.1536 0.1985
Mycobacterium tuberculosis Conserved protein 0.0042 0.0336 0.0415
Onchocerca volvulus Huntingtin homolog 0.0143 0.1516 0.1959
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0499 0.5682 0.7342
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.005 0.0044
Echinococcus multilocularis Tubulin alpha 1 chain 0.0144 0.1536 0.1536
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0021 0.0026
Toxoplasma gondii beta tubulin 0.0165 0.1775 0.2293
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0407 0.0526
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0074
Echinococcus multilocularis musashi 0.0057 0.0509 0.0509
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0407 0.0507
Trypanosoma cruzi zeta tubulin, putative 0.0052 0.0448 0.0561
Schistosoma mansoni lozenge 0.0063 0.0577 0.068
Leishmania major ATP-dependent phosphofructokinase 0.0116 0.1206 0.1541
Echinococcus granulosus cathepsin l1 0.002 0.0073 0.0086
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0212 0.0247
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0116 0.1206 0.1541
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0084 0.0109
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Onchocerca volvulus 0.0053 0.0464 0.0599
Brugia malayi EGF-like domain containing protein 0.0026 0.0146 0.0188
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0015 0.0022 0.0026
Brugia malayi Cell division protein ftsZ 0.0052 0.0448 0.0579
Leishmania major trypanothione reductase 0.0051 0.0437 0.0545
Mycobacterium ulcerans lipase LipD 0.0042 0.0336 0.1823
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.0229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Plasmodium vivax tubulin beta chain, putative 0.0165 0.1775 0.2293
Plasmodium falciparum alpha tubulin 1 0.0144 0.1536 0.1985
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0016 0.0026 0.0034
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0222 0.0287
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0073 0.0094
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0336 0.0336
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0009
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni cpg binding protein 0.0032 0.0225 0.0265
Schistosoma mansoni cpg binding protein 0.0032 0.0225 0.0265
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0212 0.0211
Echinococcus granulosus beta tubulin 0.0165 0.1775 0.2091
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.005 0.0058
Trypanosoma brucei zeta tubulin, putative 0.0052 0.0448 0.0561
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0653 0.0769
Giardia lamblia Beta tubulin 0.0165 0.1775 0.2271
Onchocerca volvulus 0.0042 0.0336 0.0434
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0073 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0177 0.0229
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0033 0.0039
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Echinococcus granulosus cpg binding protein 0.0032 0.0225 0.0265
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0015 0.0022 0.0028
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0068 0.0637 0.0805
Onchocerca volvulus 0.0162 0.1737 0.2244
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0674 0.774 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.000000000045487 0.000000000053597
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0229 0.0229
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Echinococcus granulosus Chromo domain 0.0013 0.000000000045487 0.000000000053597
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0073 0.0094
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0028
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0055 0.0487 0.0574
Onchocerca volvulus 0.0057 0.0509 0.0658
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Brugia malayi hypothetical protein 0.0027 0.016 0.0207
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0025 0.0032
Loa Loa (eye worm) ctsf protein 0.002 0.0073 0.0094
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0084 0.01
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0437 0.0564
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Onchocerca volvulus 0.0097 0.0979 0.1265
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0674 0.774 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0084 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Mycobacterium leprae Probable lipase LipE 0.0042 0.0336 0.2407
Loa Loa (eye worm) hypothetical protein 0.0162 0.1737 0.2244
Onchocerca volvulus 0.0165 0.1773 0.2291
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0026
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0229 0.0296
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0212 0.0274
Brugia malayi Heterochromatin protein 1 0.0081 0.0795 0.1027
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0229 0.0296
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0146 0.0146
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0015 0.002
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0336 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0177 0.0229
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0229 0.0277
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0052 0.0448 0.0579
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Echinococcus multilocularis Ankyrin 0.0016 0.0026 0.0026
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0407 0.0526
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0336 0.0395
Toxoplasma gondii alpha-tubulin I, putative 0.0144 0.1536 0.1985
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0325 0.042
Toxoplasma gondii thioredoxin reductase 0.0051 0.0437 0.0564
Echinococcus granulosus enteropeptidase 0.0165 0.1773 0.2089
Echinococcus multilocularis chromobox protein 1 0.0081 0.0795 0.0795
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0078 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Onchocerca volvulus Cathepsin L homolog 0.002 0.0073 0.0094
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0015 0.0022 0.0022
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0128 0.1346 0.1723
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0229 0.0277
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0437 0.0514
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Brugia malayi TAR-binding protein 0.0132 0.1388 0.1794
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0026
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.012 0.0594
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0052 0.0448 0.0579
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0336 0.0434
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0084 0.0109
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0033 0.0023
Plasmodium vivax RNA helicase-1, putative 0.0674 0.774 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0229 0.0277
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0024 0.0032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0081 0.0105
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.005 0.0195
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0418 0.054
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.0653 0.0653
Schistosoma mansoni cpg binding protein 0.0031 0.0204 0.024
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.005 0.0064
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0084 0.0109
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0163 0.7002
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0767 0.0767
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0229 0.0296
Echinococcus granulosus tubulin alpha 1C chain 0.0144 0.1536 0.181
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0336 0.0434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0084 0.01
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Trypanosoma brucei epsilon tubulin 0.0119 0.1235 0.158
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0021 0.0021
Plasmodium falciparum tubulin beta chain 0.0165 0.1775 0.2293
Trichomonas vaginalis tubulin epsilon chain, putative 0.0165 0.1775 0.2293
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0015 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0437 0.0545
Trypanosoma brucei cytochrome P450, putative 0.0024 0.012 0.0135
Echinococcus multilocularis enteropeptidase 0.0165 0.1773 0.1773
Brugia malayi Tubulin beta-1 chain 0.0165 0.1775 0.2293
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Echinococcus granulosus expressed protein 0.0399 0.4519 0.5325
Brugia malayi hypothetical protein 0.0013 0.0002 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.016 0.0207
Giardia lamblia Gamma tubulin 0.0119 0.1235 0.1572
Echinococcus granulosus transmembrane protease serine 3 0.0165 0.1773 0.2089
Trypanosoma brucei tubulin gamma chain 0.0119 0.1235 0.158
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0165 0.1773 0.2291
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0674 0.774 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Brugia malayi laminin alpha chain 0.0026 0.0146 0.0188
Brugia malayi beta-lactamase family protein 0.0042 0.0336 0.0434
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Echinococcus granulosus slit 2 protein 0.0026 0.0146 0.0172
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0112 0.0144
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Entamoeba histolytica tubulin gamma chain 0.0119 0.1235 0.1596
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.005 0.0065
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0073 0.0094
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0229 0.0296
Schistosoma mansoni hypothetical protein 0.0015 0.0024 0.0029
Echinococcus granulosus tubulin alpha 1C chain 0.0144 0.1536 0.181
Onchocerca volvulus 0.0165 0.1773 0.2291
Plasmodium falciparum tubulin gamma chain 0.0119 0.1235 0.1596
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Loa Loa (eye worm) beta-tubulin 0.0165 0.1775 0.2293
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0407 0.0526
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Loa Loa (eye worm) hypothetical protein 0.0077 0.0749 0.0968
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0013 0.000000000045487 0.000000000058772
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0674 0.774 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.02 0.0259
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Entamoeba histolytica hypothetical protein 0.0021 0.0084 0.0109
Echinococcus granulosus eukaryotic initiation factor 4A 0.0674 0.774 0.912
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Brugia malayi tubulin alpha chain - mouse 0.0144 0.1536 0.1985
Loa Loa (eye worm) tubulin alpha 2 0.0026 0.0145 0.0187
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0229 0.0296
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.005 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Brugia malayi hypothetical protein 0.0165 0.1773 0.2291
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.000000000045487 0.000000000058772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0181 0.0234
Trichomonas vaginalis tubulin beta chain, putative 0.0165 0.1775 0.2293
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0377 0.0487
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0509 0.0658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Brugia malayi hypothetical protein 0.0276 0.3071 0.3967
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0188
Brugia malayi DNA polymerase alpha catalytic subunit 0.0044 0.0365 0.0472
Echinococcus multilocularis cysteine protease 0.002 0.0073 0.0073
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0293 0.0359
Mycobacterium tuberculosis Probable reductase 0.0115 0.1195 0.1528
Schistosoma mansoni hypothetical protein 0.0165 0.1773 0.2089
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Leishmania major cathepsin L-like protease 0.0074 0.0715 0.0906
Echinococcus granulosus GPCR family 2 0.0033 0.0229 0.027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Mycobacterium tuberculosis Cell division protein FtsZ 0.0052 0.0448 0.0561
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.016 0.0187
Brugia malayi hypothetical protein 0.0499 0.5682 0.7342
Brugia malayi Tubulin beta chain 0.0067 0.0631 0.0816
Plasmodium falciparum eukaryotic initiation factor 4A 0.0674 0.774 1
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0084 0.01
Loa Loa (eye worm) hypothetical protein 0.0046 0.0377 0.0487
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0674 0.774 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0024 0.0032
Onchocerca volvulus 0.0031 0.0204 0.0264
Loa Loa (eye worm) fibroinase 0.002 0.0073 0.0094
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0068 0.0637 0.0805
Trichomonas vaginalis tubulin epsilon chain, putative 0.0052 0.0448 0.0579
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.1206 0.1558
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0115 0.1195 0.1528
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0336 0.0415
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0229 0.0229
Onchocerca volvulus 0.002 0.0073 0.0094
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0674 0.774 1
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.1388 0.1794
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0229 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Loa Loa (eye worm) hypothetical protein 0.0143 0.1516 0.1959
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0015 0.0022 0.0028
Onchocerca volvulus 0.0082 0.0809 0.1045
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0084 0.0084
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.005 0.0064
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0084 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Plasmodium falciparum thioredoxin reductase 0.0051 0.0437 0.0564
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0448 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0407 0.048
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.016 0.0207
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0163 0.0211
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0418 0.054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Plasmodium falciparum glutathione reductase 0.0051 0.0437 0.0564
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0336 0.0434
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0336 0.0434
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0795 0.1027
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni hypothetical protein 0.0013 0.000000000045487 0.000000000053597
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0293 0.0359
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0073 0.0086
Onchocerca volvulus 0.0042 0.0336 0.0434
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Giardia lamblia GTOR 0.0048 0.0407 0.0499
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0715 0.0906
Toxoplasma gondii beta-tubulin, putative 0.0165 0.1775 0.2293
Toxoplasma gondii beta-1 tubulin, putative 0.0165 0.1775 0.2293
Entamoeba histolytica cysteine protease, putative 0.002 0.0073 0.0094
Mycobacterium ulcerans cell division protein FtsZ 0.0052 0.0448 0.2464
Echinococcus granulosus tubulin alpha 3 chain 0.0144 0.1536 0.181
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0674 0.774 0.912
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0024 0.0125 0.0142
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Toxoplasma gondii DNA polymerase family B protein 0.0015 0.0022 0.0028
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.005 0.0064
Toxoplasma gondii kringle domain-containing protein 0.0018 0.005 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Loa Loa (eye worm) hypothetical protein 0.0056 0.0497 0.0642
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0336 0.0415
Echinococcus granulosus microtubule associated protein 2 0.0738 0.8487 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0229 0.0277
Loa Loa (eye worm) tubulin alpha-2 chain 0.0144 0.1536 0.1985
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0163 0.0192
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0336 0.0434
Trichomonas vaginalis tubulin alpha chain, putative 0.0119 0.1235 0.1596
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.005 0.0044
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0165 0.1773 0.2089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.005 0.0064
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.005 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0015 0.0022 0.0022
Schistosoma mansoni slit 0.0026 0.0146 0.0172
Echinococcus granulosus tubulin delta chain 0.0052 0.0448 0.0528
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0631 0.0816
Loa Loa (eye worm) alpha-tubulin 0.0144 0.1536 0.1985
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0073 0.0094
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0084 0.0109
Schistosoma mansoni survival motor neuron protein 0.0056 0.0502 0.0592
Brugia malayi Tubulin alpha-2 chain 0.0144 0.1536 0.1985
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.012 0.0135
Echinococcus multilocularis pikachurin 0.0026 0.0146 0.0146
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus dnaJ subfamily B 0.0437 0.4967 0.5853
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0115 0.1195 0.8867
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0079 0.0102
Entamoeba histolytica tubulin alpha chain, putative 0.0144 0.1536 0.1985
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.1206 0.1541
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0044 0.0056
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Onchocerca volvulus 0.0165 0.1773 0.2291
Plasmodium falciparum tubulin delta chain, putative 0.0052 0.0448 0.0579
Schistosoma mansoni hypothetical protein 0.0437 0.4967 0.5853
Brugia malayi Tubulin alpha chain 0.0144 0.1536 0.1985
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0016 0.0026 0.0034
Echinococcus multilocularis beta tubulin 0.0165 0.1775 0.1775
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0674 0.774 0.912
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0229 0.0277
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.005 0.0044
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Plasmodium vivax tubulin epsilon chain, putative 0.0119 0.1235 0.1596
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0094
Echinococcus granulosus Tubulin alpha 1 chain 0.0144 0.1536 0.181
Brugia malayi cytochrome P450 0.0015 0.0015 0.002
Plasmodium falciparum thioredoxin reductase 0.0018 0.005 0.0064
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Schistosoma mansoni hypothetical protein 0.0055 0.0492 0.058
Brugia malayi beta-lactamase 0.0042 0.0336 0.0434
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0336 0.0415
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.1059 0.1369
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0502 0.0649
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.012 0.0135
Schistosoma mansoni microtubule-associated protein tau 0.0738 0.8487 1
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0028
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0795 0.1027
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0026 0.0146 0.0188
Mycobacterium leprae cell division protein FtsZ 0.0052 0.0448 0.3254
Schistosoma mansoni netrin receptor unc5 0.0015 0.0024 0.0029
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0111 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Trichomonas vaginalis set domain proteins, putative 0.0543 0.6206 0.8019
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0437 0.0437
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0055 0.0065
Echinococcus multilocularis slit 2 protein 0.0026 0.0146 0.0146
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Loa Loa (eye worm) hypothetical protein 0.0053 0.0464 0.0599
Entamoeba histolytica tubulin alpha-1 chain 0.0144 0.1536 0.1985
Brugia malayi hypothetical protein 0.0143 0.1516 0.1959
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0407 0.0407
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0229 0.0229
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Trypanosoma brucei alpha tubulin, putative 0.0067 0.0631 0.0798
Onchocerca volvulus DNA polymerase homolog 0.0015 0.0022 0.0028
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0229 0.0277
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0336 0.0415
Leishmania major epsilon tubulin, putative 0.0119 0.1235 0.158
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0715 0.0906
Echinococcus multilocularis tubulin gamma 1 chain 0.0119 0.1235 0.1235
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0407 0.0526
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0165 0.1775 0.1775
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.1206 0.1421
Echinococcus multilocularis tubulin alpha 3 chain 0.0144 0.1536 0.1536
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0033 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.021 0.0271
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0715 0.0906
Onchocerca volvulus 0.0543 0.6208 0.8021
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0336 0.0434
Echinococcus multilocularis transmembrane protease serine 3 0.0165 0.1773 0.1773
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0407 0.0507
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0044 0.0056
Loa Loa (eye worm) hypothetical protein 0.0071 0.0675 0.0872
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.005 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0084 0.01
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0212 0.0274
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0675 0.0872
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0229 0.0229
Echinococcus granulosus tubulin alpha 0.0119 0.1235 0.1456
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0163 0.0211
Entamoeba histolytica hypothetical protein 0.0013 0.000000000045487 0.000000000058772
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0084 0.01
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0024 0.0125 0.0161
Trichomonas vaginalis tubulin gamma chain, putative 0.0119 0.1235 0.1596
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0529 0.0664
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Echinococcus multilocularis tar DNA binding protein 0.0132 0.1388 0.1388
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Schistosoma mansoni chromobox protein 0.0081 0.0795 0.0937
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.005 0.0036
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0044 0.0365 0.0472
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0112 0.0144
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Plasmodium vivax hypothetical protein, conserved 0.0013 0.000000000045487 0.000000000058772
Echinococcus granulosus Mastin 0.0165 0.1773 0.2089
Loa Loa (eye worm) hypothetical protein 0.0499 0.5682 0.7342
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.005 0.0059
Echinococcus multilocularis lamin 0.0057 0.0509 0.0509
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0191
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus multilocularis lamin dm0 0.0057 0.0509 0.0509
Plasmodium vivax SET domain protein, putative 0.0069 0.0653 0.0844
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0336 0.2407
Giardia lamblia Alpha-tubulin 0.0144 0.1536 0.1962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0653 0.0769
Loa Loa (eye worm) tubulin gamma chain 0.0119 0.1235 0.1596
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Echinococcus multilocularis tubulin subunit TubB 0.0144 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.005 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0222 0.0286
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0073 0.0073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0073 0.0073
Echinococcus granulosus L aminoadipate semialdehyde 0.0097 0.0979 0.1153
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0084 0.01
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0084 0.0109
Giardia lamblia DNA polymerase alpha subunit A 0.0046 0.0388 0.0475
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.0637 0.3539
Giardia lamblia Beta tubulin 0.0165 0.1775 0.2271
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0015 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0631 0.0816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0191
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0674 0.774 0.774
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0144 0.1536 0.1985
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.000000000045487 0.000000000058772
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0212 1
Trypanosoma brucei zeta tubulin 0.0052 0.0448 0.0561
Loa Loa (eye worm) tubulin beta-4 chain 0.0165 0.1775 0.2293
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0188
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0015 0.0022 0.0009
Onchocerca volvulus 0.002 0.0073 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0637 0.075
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0084 0.01
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.005 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0263 0.034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Mycobacterium tuberculosis Probable dehydrogenase 0.0115 0.1195 0.1528
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.005 0.0044
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0767 0.0903
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0229 0.0296
Onchocerca volvulus 0.0067 0.0631 0.0816
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.2983 0.3842
Brugia malayi Cytochrome P450 family protein 0.0024 0.012 0.0155
Echinococcus multilocularis peroxisome assembly protein 26 0.0144 0.1536 0.1536
Trichomonas vaginalis tubulin, putative 0.0165 0.1775 0.2293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Trypanosoma brucei trypanothione reductase 0.0051 0.0437 0.0545
Schistosoma mansoni tubulin subunit epsilon 0.0119 0.1235 0.1456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0015 0.0022 0.0028
Onchocerca volvulus 0.002 0.0073 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.005 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0407 0.0526
Onchocerca volvulus Cathepsin L homolog 0.002 0.0073 0.0094
Loa Loa (eye worm) tubulin alpha 2 0.0093 0.0932 0.1204
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.1206 0.1558
Echinococcus granulosus tubulin subunit TubB 0.0144 0.1536 0.181
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0336 0.0415
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.1206 0.1558
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0336 0.0434
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0674 0.774 1
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0084 0.01
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0073 0.0094
Plasmodium vivax glutathione reductase, putative 0.0051 0.0437 0.0564
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0082 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0036 0.0262 0.0339
Onchocerca volvulus 0.0165 0.1773 0.2291
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0027 0.0163 0.0843
Loa Loa (eye worm) BEN-1 protein 0.0165 0.1775 0.2293
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Giardia lamblia Beta tubulin 0.0165 0.1775 0.2271
Echinococcus multilocularis Protein lozenge 0.0063 0.0577 0.0577
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0377 0.0487
Giardia lamblia Epsilon tubulin 0.0052 0.0448 0.0553
Brugia malayi Protein kinase domain containing protein 0.0018 0.005 0.0065
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0229 0.0296
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Echinococcus multilocularis microtubule associated protein 2 0.0738 0.8487 0.8487
Echinococcus multilocularis neuropeptide receptor A26 0.0539 0.6154 0.6154
Entamoeba histolytica hypothetical protein 0.0021 0.0084 0.0109
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Onchocerca volvulus 0.0018 0.005 0.0065
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.1418 0.1832
Echinococcus granulosus tumor protein p63 0.0361 0.4076 0.4803
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0034
Leishmania major gamma-tubulin 0.0119 0.1235 0.158
Echinococcus granulosus alpha tubulin 0.0144 0.1536 0.181
Echinococcus granulosus tubulin gamma 1 chain 0.0119 0.1235 0.1456
Leishmania major cytochrome p450-like protein 0.0024 0.012 0.0135
Schistosoma mansoni tubulin subunit alpha 0.0144 0.1536 0.181
Mycobacterium ulcerans 6-phosphofructokinase 0.0116 0.1206 0.6773
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0437 0.0545
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.0653 0.0844
Onchocerca volvulus 0.002 0.0073 0.0094
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0084 0.01
Schistosoma mansoni lamin 0.0057 0.0509 0.06
Brugia malayi SET domain containing protein 0.0016 0.0037 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0509 0.0658
Echinococcus granulosus death domain containing protein 0.0015 0.0024 0.0029
Echinococcus multilocularis Chromo domain 0.0013 0.000000000045487 0.000000000045487
Schistosoma mansoni intermediate filament proteins 0.0057 0.0509 0.06
Brugia malayi Cytochrome P450 family protein 0.0024 0.012 0.0155
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Schistosoma mansoni lamin 0.0057 0.0509 0.06
Loa Loa (eye worm) cytochrome P450 0.0015 0.0015 0.002
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni hypothetical protein 0.0071 0.0675 0.0795
Brugia malayi eukaryotic initiation factor 4A 0.0674 0.774 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0027 0.0163 0.0148
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Mycobacterium ulcerans beta-lactamase 0.0042 0.0336 0.1823
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0212 0.0274
Trichomonas vaginalis tubulin gamma chain, putative 0.0119 0.1235 0.1596
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0418 0.054
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.005 0.0064
Leishmania major eukaryotic initiation factor 4a, putative 0.0674 0.774 1
Loa Loa (eye worm) abnormal epIthelia family member 0.0026 0.0146 0.0188
Echinococcus granulosus tubulin alpha 3 chain 0.0144 0.1536 0.181
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0407 0.0507
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0437 0.0564
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0084 0.0084
Brugia malayi Kringle domain containing protein 0.0018 0.005 0.0065
Leishmania major hypothetical protein, conserved 0.0018 0.005 0.0046
Echinococcus granulosus tar DNA binding protein 0.0132 0.1388 0.1636
Trypanosoma cruzi tubulin delta chain 0.0052 0.0448 0.0561
Echinococcus granulosus Chromobox protein 3 0.0013 0.00000004398 0.000000051821
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0084 0.01
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0084 0.01
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Echinococcus multilocularis beta tubulin 0.0165 0.1775 0.1775
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.005 0.0195
Plasmodium vivax DNA polymerase alpha, putative 0.0044 0.0365 0.0472
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.047 0.0607
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0024 0.0024
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0084 0.0109
Brugia malayi Tubulin gamma chain 0.0119 0.1235 0.1596
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0464 0.0547
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0336 0.1823
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.3071 0.3071
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0097 0.0979 0.1265
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0033 0.0033
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.1059 0.1369
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0057 0.0509 0.0658
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Loa Loa (eye worm) hypothetical protein 0.0027 0.016 0.0207
Schistosoma mansoni hypothetical protein 0.0165 0.1773 0.2089
Brugia malayi Tubulin alpha-2 chain 0.0144 0.1536 0.1985
Brugia malayi phosphofructokinase 0.0116 0.1206 0.1558
Trichomonas vaginalis tubulin epsilon chain, putative 0.0144 0.1536 0.1985
Echinococcus granulosus peroxisome assembly protein 26 0.0144 0.1536 0.181
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis tubulin gamma chain, putative 0.0165 0.1775 0.2293
Echinococcus granulosus lamin dm0 0.0057 0.0509 0.06
Echinococcus granulosus lamin 0.0057 0.0509 0.06
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0073 0.0086
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0336 0.0395
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0146 0.0172
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0015 0.0022 0.0026
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.1773
Plasmodium vivax vivapain-2 0.002 0.0073 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0448 0.0579
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0093 0.0932 0.1204
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0084 0.01
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.0616 0.0725
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0052 0.0448 1
Trypanosoma brucei beta tubulin 0.0119 0.1235 0.158
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0229 0.027
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.005 0.0046
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0009
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0795 0.1027
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.000000000045487 0.000000000045487
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.012 0.0155
Loa Loa (eye worm) glutathione reductase 0.0051 0.0437 0.0564
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Echinococcus multilocularis glycoprotein Antigen 5 0.0165 0.1773 0.1773
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.0637 0.3539
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Leishmania major zeta tubulin, putative 0.0052 0.0448 0.0561
Loa Loa (eye worm) alpha-tubulin 0.0144 0.1536 0.1985
Entamoeba histolytica tubulin family protein 0.0165 0.1775 0.2293
Brugia malayi Cytochrome P450 family protein 0.0053 0.047 0.0607
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Echinococcus granulosus tubulin beta 1 chain 0.0165 0.1775 0.2091
Echinococcus multilocularis Tubulin alpha 1 chain 0.0144 0.1536 0.1536
Echinococcus granulosus pikachurin 0.0026 0.0146 0.0172
Onchocerca volvulus 0.0013 0.00000004398 0.000000056824
Loa Loa (eye worm) hypothetical protein 0.0075 0.0727 0.094
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0165 0.0195
Echinococcus granulosus tubulin beta 4A class IVa 0.0165 0.1775 0.2091
Toxoplasma gondii cathepsin CPL 0.002 0.0073 0.0094
Brugia malayi beta-lactamase family protein 0.0042 0.0336 0.0434
Loa Loa (eye worm) trypsin family protein 0.0165 0.1773 0.2291
Schistosoma mansoni tubulin subunit alpha 0.0144 0.1536 0.181
Echinococcus multilocularis geminin 0.0388 0.439 0.439
Trypanosoma cruzi tubulin delta chain 0.0052 0.0448 0.0561
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Plasmodium falciparum glutathione reductase 0.0018 0.005 0.0064
Entamoeba histolytica tubulin family protein 0.0165 0.1775 0.2293
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.027
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.0637 0.0637
Brugia malayi beta-tubulin, identical 0.0165 0.1775 0.2293
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.1206 0.1421
Mycobacterium leprae conserved hypothetical protein 0.0027 0.0163 0.1114
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.4967 0.4967
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0023 0.003
Echinococcus granulosus tubulin epsilon chain 0.0119 0.1235 0.1456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Onchocerca volvulus 0.0056 0.0502 0.0649

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 8 % Inhibition of strand rejoining activity of human DNA topoisomerase 2 assessed as protein-DNA complex formation at 20 uM by cell-based assay ChEMBL. 1331331
ID50 (binding) = 50 uM Inhibition of human DNA topoisomerase 2 ChEMBL. 1331331

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.