Detailed information for compound 1014302

Basic information

Technical information
  • TDR Targets ID: 1014302
  • Name: 70748-49-1
  • MW: 302.451 | Formula: C20H30O2
  • H donors: 0 H acceptors: 0 LogP: 2.8 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/C/1=C\CC[C@]2(C)O[C@H]2CC/C(=C/[C@H]2C(=C(C)CO2)CC1)/C
  • InChi: 1S/C20H30O2/c1-14-6-5-11-20(4)19(22-20)10-8-15(2)12-18-17(9-7-14)16(3)13-21-18/h6,12,18-19H,5,7-11,13H2,1-4H3/b14-6+,15-12+/t18-,19-,20-/m0/s1
  • InChiKey: OQGXDKRHMBRZCS-FXFXMZOASA-N  


Substructure search Similarity search

Network

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Synonyms

  • Oxireno(9,10)cyclotetradeca(1,2-b)furan, 1a,2,3,6,7,9,10a,13,14,14a-decahydro-1a,5,8,12-tetramethyl-, (1aR,4E,10aR,11E,14aR)-rel-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0187 0.0187
Echinococcus multilocularis serotonin receptor 0.0051 0.009 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Leishmania major glycerol uptake protein, putative 0.0771 0.1663 1
Brugia malayi putative neuropeptide receptor 0.0051 0.009 0.009
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0034 0.0034
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Trichomonas vaginalis ABC transporter, putative 0.001 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.0668 0.1439 0.1439
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.009 0.009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0208 0.0434 0.3328
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.01
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0012 0.0012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0017 0.0017
Echinococcus granulosus zinc finger protein 0.0024 0.0032 0.0032
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0102 0.02 0.1524
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0187 0.0187
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.009 0.009
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0094 0.0563
Echinococcus granulosus microtubule associated protein 2 0.0678 0.1462 0.1462
Loa Loa (eye worm) nuclear hormone receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0012 0.0012
Echinococcus multilocularis neuropeptide receptor 0.0051 0.009 0.009
Onchocerca volvulus 0.0051 0.009 0.0535
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni multidrug resistance protein 0.001 0.0001 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0038 0.0266
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0027 0.0027
Onchocerca volvulus Glucosylceramidase homolog 0.0173 0.0356 0.2138
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0038 0.0038
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0263 0.0554 0.0554
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0095
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.0001 0.0001
Onchocerca volvulus Huntingtin homolog 0.0132 0.0267 0.1603
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.009 0.009
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.0225 0.1355
Entamoeba histolytica hypothetical protein 0.0113 0.0225 0.1355
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.009 0.009
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0034 0.0034
Loa Loa (eye worm) Smad1 0.0025 0.0034 0.0034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0024 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0042 0.0041
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.009 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0024 0.0146
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0071 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Echinococcus multilocularis polycomb protein SCMH1 0.0057 0.0103 0.0103
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0012 0.0012
Plasmodium falciparum protein serine/threonine kinase-1 0.0059 0.0106 0.0105
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0133 0.0133
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0011 0.0001 0.0003
Leishmania major hypothetical protein, conserved 0.0015 0.0011 0.0062
Leishmania major protein kinase, putative 0.0059 0.0106 0.0634
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0059 0.0106 0.064
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0027 0.0027
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.009 0.009
Mycobacterium tuberculosis Conserved protein 0.0071 0.0133 0.1017
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 0.2426
Onchocerca volvulus 0.0051 0.009 0.0535
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.009 0.009
Echinococcus multilocularis muscleblind protein 0.0179 0.0369 0.0369
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.009 0.009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.4584 1 1
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0011 0.0003 0.0021
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0027 0.0027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.009 0.009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0433 0.0433
Schistosoma mansoni Smad4 0.0025 0.0034 0.0034
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.009 0.009
Brugia malayi hypothetical protein 0.0034 0.0053 0.0053
Brugia malayi follicle stimulating hormone receptor 0.0051 0.009 0.009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0111 0.0111
Loa Loa (eye worm) hhat protein 0.0771 0.1663 0.1663
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0027 0.0027
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0027 0.0027
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Echinococcus granulosus dual specificity protein kinase clk2 0.0059 0.0106 0.0106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0027 0.0027
Echinococcus multilocularis multidrug resistance protein 1 0.001 0.0001 0.0001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0024 0.2022
Onchocerca volvulus 0.0051 0.009 0.0535
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.001 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0051 0.009 0.009
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0001 0.0001
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0067 0.0067
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0004 0.0004
Echinococcus granulosus geminin 0.0668 0.1439 0.1439
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0053 0.0095 0.0094
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0208 0.0434 0.0434
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0063 0.0063
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.4584 1 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0011 0.0003 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0225 0.0225
Brugia malayi MH1 domain containing protein 0.0025 0.0034 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0003 0.0003
Schistosoma mansoni biogenic amine receptor 0.0051 0.009 0.009
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0012 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Mycobacterium leprae Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.0603 0.1296 1
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.0003 0.0021
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.003
Schistosoma mansoni Smad4 0.0011 0.0003 0.0003
Trypanosoma brucei ISWI complex protein 0.0015 0.0011 0.0068
Schistosoma mansoni neuropeptide receptor 0.0051 0.009 0.009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0133 0.0133
Mycobacterium tuberculosis Conserved protein 0.0071 0.0133 0.1017
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0001 0.0001
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0012 0.0073
Brugia malayi hypothetical protein 0.0271 0.0571 0.0571
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0771 0.1663 0.1663
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0038 0.0222
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0027 0.0027
Brugia malayi MBOAT family protein 0.0771 0.1663 0.1663
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0011 0.0003 0.0021
Echinococcus granulosus polycomb protein SCMH1 0.0057 0.0103 0.0103
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.009 0.009
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0011 0.0003 0.0019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0038 0.0285
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0115 0.0229 0.0229
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.009 0.009
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0023 0.0022
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0011 0.0003 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0047 0.0081 0.0081
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.009 0.009
Brugia malayi steroid hormone receptor 0.0022 0.0027 0.0027
Onchocerca volvulus 0.0051 0.009 0.0535
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus multilocularis somatostatin receptor 0.0051 0.009 0.009
Echinococcus multilocularis Smad4 0.0025 0.0034 0.0034
Brugia malayi conserved hypotetical protein 0.0011 0.0001 0.0001
Treponema pallidum alginate O-acetylation protein (algI) 0.0771 0.1663 1
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0003 0.0003
Echinococcus granulosus expressed protein 0.0017 0.0015 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0024 0.0146
Loa Loa (eye worm) hypothetical protein 0.0058 0.0105 0.0105
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.009 0.009
Echinococcus multilocularis expressed protein 0.0017 0.0015 0.0015
Giardia lamblia PHD finger protein 15 0.0029 0.0042 0.3775
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0045 0.0045
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.003 0.003
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0771 0.1663 0.1663
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0027 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0038 0.0266
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0132 0.0267 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Trypanosoma cruzi glycerol uptake protein, putative 0.0771 0.1663 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0012 0.0073
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.009 0.009
Echinococcus granulosus ferritin 0.0017 0.0015 0.0015
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0011 0.0003 0.0003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0011 0.0003 0.0003
Echinococcus multilocularis peptidase Clp (S14 family) 0.0102 0.02 0.02
Toxoplasma gondii hypothetical protein 0.0771 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0771 0.1663 0.1663
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0106 0.064
Schistosoma mansoni coup transcription factor 0.0022 0.0027 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0771 0.1663 0.1663
Echinococcus granulosus survival motor neuron protein 1 0.0271 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi multidrug resistance protein 3 0.001 0.0001 0.0001
Onchocerca volvulus Huntingtin homolog 0.0132 0.0267 0.1603
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.3814 0.8316 0.8316
Mycobacterium ulcerans hypothetical protein 0.0027 0.0038 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0027 0.0027
Echinococcus multilocularis dual specificity protein kinase clk2 0.0059 0.0106 0.0106
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.009 0.009
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0015 0.0105
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0301 0.0301
Giardia lamblia Kinase, CMGC CLK 0.0059 0.0106 1
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0027 0.0027
Echinococcus multilocularis sex peptide receptor 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Brugia malayi hypothetical protein 0.0113 0.0225 0.0225
Trichomonas vaginalis ABC transporter, putative 0.001 0.0001 0.0006
Trichomonas vaginalis set domain proteins, putative 0.0237 0.0496 0.2984
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0133 0.0999
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.009 0.009
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0251 0.0528 0.0528
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.001 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0668 0.1439 0.1439
Schistosoma mansoni hypothetical protein 0.0206 0.0429 0.0429
Trichomonas vaginalis abcb9, putative 0.001 0.0001 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0057 0.0103 0.0103
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0038 0.0228
Entamoeba histolytica P-glyco protein 6, putative 0.001 0.0001 0.0006
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0155 0.0317 0.0316
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0038 0.0266
Echinococcus multilocularis multidrug resistance protein 1 0.001 0.0001 0.0001
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0064 0.5884
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.004 0.004
Brugia malayi GnHR receptor homolog 0.0051 0.009 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Toxoplasma gondii pantoate-beta-alanine ligase 0.0603 0.1296 0.1296
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0084 0.0084
Plasmodium vivax serine/threonine kinase-1, putative 0.0059 0.0106 0.0105
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0133 0.0798
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0081 0.0081
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.003 0.003
Schistosoma mansoni Smad4 0.0011 0.0003 0.0003
Echinococcus granulosus orexin receptor type 2 0.0051 0.009 0.009
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Echinococcus multilocularis serotonin receptor 0.0051 0.009 0.009
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0133 0.1017
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0034 0.0034
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.0001 0.0001
Schistosoma mansoni smad1 5 8 and 0.0025 0.0034 0.0034
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0027 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0011 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0027 0.0027
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Brugia malayi ecdysteroid receptor 0.0022 0.0027 0.0027
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0155 0.0317 0.0317
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0024 0.014
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0133 0.1017
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0001 0.0001
Trichomonas vaginalis transmembrane protein nessy, putative 0.0771 0.1663 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0771 0.1663 0.1663
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0004 0.0004
Brugia malayi Pre-SET motif family protein 0.0208 0.0433 0.0433
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0155 0.0317 0.0317
Toxoplasma gondii hypothetical protein 0.0053 0.0095 0.0095
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0017
Mycobacterium ulcerans beta-lactamase 0.0071 0.0133 0.0999
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0771 0.1663 0.1663
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0004 0.0004
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.01
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.001 0.0001 0.0006
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0011 0.0003 0.0021
Mycobacterium tuberculosis Conserved protein 0.0071 0.0133 0.1017
Onchocerca volvulus 0.0051 0.009 0.0535
Brugia malayi PHD-finger family protein 0.0013 0.0007 0.0007
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0017
Brugia malayi Bromodomain containing protein 0.0035 0.0055 0.0055
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0071 0.0133 0.0792
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0077 0.0462
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Onchocerca volvulus 0.0022 0.0027 0.0159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0093 0.0093
Echinococcus multilocularis microtubule associated protein 2 0.0678 0.1462 0.1462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0045 0.0045
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0133 0.0999
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0027 0.0027
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.009 0.009
Echinococcus multilocularis g protein coupled receptor 0.0051 0.009 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Brugia malayi MH2 domain containing protein 0.0025 0.0034 0.0034
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0771 0.1663 0.1663
Entamoeba histolytica vacuolar protein sorting 26 0.0771 0.1663 1
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0251 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Onchocerca volvulus 0.0051 0.009 0.0535
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0133 0.0999
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi aldehyde dehydrogenase 0.0011 0.0003 0.0003
Entamoeba histolytica P-glycoprotein-5 0.001 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0094 0.0094
Brugia malayi Serotonin receptor 0.0051 0.009 0.009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0045 0.0045
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0208 0.0434 0.2604
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0027 0.0027
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0011 0.0003 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.009 0.009
Echinococcus granulosus dnaJ subfamily B 0.0399 0.0852 0.0852
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0094 0.0093
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0047 0.0081 0.0081
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0011 0.0003 0.0015
Echinococcus multilocularis ferritin 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis 0.0058 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0015 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.009 0.009
Schistosoma mansoni ferritin light chain 0.0017 0.0015 0.0015
Echinococcus granulosus o acyltransferase membrane bound domain 0.0771 0.1663 0.1663
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.009 0.009
Echinococcus multilocularis SAM and MBT domain containing protein 0.0057 0.0103 0.0103
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0027 0.0027
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0027 0.0159
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.0001 0.0001
Brugia malayi isocitrate dehydrogenase 0.0015 0.0012 0.0012
Onchocerca volvulus 0.003 0.0045 0.0264
Mycobacterium ulcerans aldehyde dehydrogenase 0.0208 0.0434 0.3328
Echinococcus granulosus o acyltransferase membrane bound domain 0.0771 0.1663 0.1663
Schistosoma mansoni ferritin 0.0017 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0047 0.0081 0.0081
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0017
Plasmodium falciparum phd finger protein, putative 0.0029 0.0042 0.0041
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.009 0.009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0038 0.0266
Brugia malayi ORL1-like opioid receptor 0.0051 0.009 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0094 0.0093
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi larval opioid receptor 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0059 0.0108 0.0108
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.009 0.009
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0011 0.0002 0.0002
Trichomonas vaginalis esterase, putative 0.0071 0.0133 0.0798
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0024 0.0023
Echinococcus multilocularis neuropeptide s receptor 0.0949 0.2054 0.2054
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0106 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Schistosoma mansoni peptidase Clp (S14 family) 0.0155 0.0317 0.0317
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0002 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.009 0.009
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.009 0.009
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.011 0.011
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.0001 0.0001
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0011 0.0003 0.0021
Brugia malayi nuclear receptor NHR-88 0.0022 0.0027 0.0027
Echinococcus granulosus GPCR family 2 0.0095 0.0187 0.0187
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.009 0.009
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0084 0.0084
Schistosoma mansoni sex comb on midleg homolog 0.0057 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0095 0.0187 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0011 0.0003 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.009 0.009
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.003 0.003
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0017 0.0017
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0023 0.015
Trypanosoma brucei glycerol uptake protein, putative 0.0771 0.1663 1
Schistosoma mansoni survival motor neuron protein 0.0055 0.0099 0.0099
Echinococcus granulosus g protein coupled receptor 0.0051 0.009 0.009
Schistosoma mansoni myosin xvIII 0.0051 0.009 0.009
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0042 0.0042
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0771 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0071 0.0133 0.0133
Leishmania major aldehyde dehydrogenase, putative 0.0011 0.0003 0.0015
Echinococcus multilocularis peregrin 0.0035 0.0055 0.0055
Echinococcus multilocularis histone acetyltransferase MYST2 0.0065 0.012 0.012
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0065 0.012 0.012
Entamoeba histolytica P-glycoprotein-1 0.001 0.0001 0.0006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0027 0.0027
Onchocerca volvulus 0.0071 0.0133 0.0792
Echinococcus granulosus serotonin receptor 0.0051 0.009 0.009
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0051 0.009 0.0535
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0351 0.0746 0.0746
Loa Loa (eye worm) MBOAT family protein 0.0771 0.1663 0.1663
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0554 0.3333
Loa Loa (eye worm) hypothetical protein 0.0771 0.1663 0.1663
Schistosoma mansoni hypothetical protein 0.0771 0.1663 0.1663
Trypanosoma cruzi ISWI complex protein 0.0015 0.0011 0.0068
Leishmania major hypothetical protein, conserved 0.0771 0.1663 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0102 0.02 0.154
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0017 0.01
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.009 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0179 0.0369 0.0369
Leishmania major glycerol uptake protein, putative 0.0771 0.1663 1
Echinococcus multilocularis smad 0.0025 0.0034 0.0034
Schistosoma mansoni zinc finger protein 0.0015 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0063 0.0063
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0057 0.0103 0.0103
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0263 0.0554 0.0554
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0051 0.009 0.009
Leishmania major hypothetical protein, conserved 0.0091 0.0178 0.1065
Schistosoma mansoni aldehyde dehydrogenase 0.0208 0.0434 0.0434
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0133 0.1017
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0451 0.0964 0.7434
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0027 0.0027
Schistosoma mansoni sterol O-acyltransferase 1 0.0771 0.1663 0.1663
Brugia malayi sulfakinin receptor protein 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus granulosus neuropeptide receptor 0.0051 0.009 0.009
Echinococcus multilocularis ATP binding cassette sub family B 0.001 0.0001 0.0001
Brugia malayi hypothetical protein 0.0132 0.0267 0.0267
Brugia malayi nuclear hormone receptor 0.0011 0.0001 0.0001
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0017 0.0095
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0011 0.0003 0.0019
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0017 0.01
Brugia malayi PHD-finger family protein 0.0029 0.0042 0.0042
Brugia malayi beta-lactamase 0.0071 0.0133 0.0133
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.093 0.2012 0.2012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0027 0.0027
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0011 0.0003 0.0003
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0024 0.0024
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0024 0.0146
Loa Loa (eye worm) MBCTL1 0.0065 0.012 0.012
Echinococcus granulosus multidrug resistance protein 1 0.001 0.0001 0.0001
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0027 0.0027
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0017
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0155 0.0317 0.2426
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0017 0.0095
Toxoplasma gondii exonuclease III APE 0.0021 0.0024 0.0024
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0133 0.0133
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.009 0.009
Loa Loa (eye worm) MBOAT family protein 0.0771 0.1663 0.1663
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0064 0.0063
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.009 0.009
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.003 0.003
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0133 0.1017
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Schistosoma mansoni adenoreceptor 0.0051 0.009 0.009
Trichomonas vaginalis taga, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0302 0.0638 0.0638
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0133 0.0798
Echinococcus multilocularis survival motor neuron protein 1 0.0271 0.0571 0.0571
Brugia malayi Bromodomain containing protein 0.0041 0.0069 0.0069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0056 0.0056
Echinococcus granulosus neuropeptide s receptor 0.0949 0.2054 0.2054
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Brugia malayi MBOAT family protein 0.0771 0.1663 0.1663
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.009 0.009
Loa Loa (eye worm) nuclear receptor NHR-67 0.0011 0.0001 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0094 0.0563
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.009 0.009
Entamoeba histolytica hypothetical protein 0.0113 0.0225 0.1355
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0024 0.0146
Echinococcus granulosus sex peptide receptor 0.0051 0.009 0.009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.009 0.009
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.0603 0.1296 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0058 0.0347
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni multidrug resistance protein 0.001 0.0001 0.0001
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0063 0.0063
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.0001 0.0001
Echinococcus granulosus smad 0.0025 0.0034 0.0034
Echinococcus multilocularis GPCR, family 2 0.0095 0.0187 0.0187
Brugia malayi MH2 domain containing protein 0.0025 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Brugia malayi hypothetical protein 0.0053 0.0094 0.0094
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0003 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus multilocularis tumor protein p63 0.0691 0.149 0.149
Loa Loa (eye worm) nuclear factor I 0.0014 0.0009 0.0009
Brugia malayi nuclear receptor RXR 0.0011 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0771 0.1663 1
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0027 0.0027
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0771 0.1663 0.1663
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0038 0.0038
Echinococcus granulosus o acyltransferase membrane bound domain 0.0771 0.1663 0.1663
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0059 0.0106 0.0106
Schistosoma mansoni biogenic amine receptor 0.0051 0.009 0.009
Schistosoma mansoni amine GPCR 0.0051 0.009 0.009
Brugia malayi neuropeptide F receptor 0.0051 0.009 0.009
Echinococcus granulosus Smad4 0.0025 0.0034 0.0034
Trichomonas vaginalis ABC transporter, putative 0.001 0.0001 0.0006
Brugia malayi MBOAT family protein 0.0771 0.1663 0.1663
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0302 0.0638 0.0638
Echinococcus multilocularis neuropeptide receptor 0.0051 0.009 0.009
Onchocerca volvulus 0.0051 0.009 0.0535
Echinococcus granulosus allatostatin A receptor 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0023 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0024 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0077 0.0462
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0011 0.0003 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0047 0.0081 0.0081
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Onchocerca volvulus 0.0051 0.009 0.0535
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0027 0.0027
Echinococcus granulosus somatostatin receptor 0.0051 0.009 0.009
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0027 0.0027
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.009 0.009
Brugia malayi Aldehyde dehydrogenase protein 4 0.0011 0.0003 0.0003
Schistosoma mansoni opsin-like receptor 0.0051 0.009 0.009
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0229 0.0479 0.0479
Schistosoma mansoni hypothetical protein 0.0029 0.0042 0.0042
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0017 0.01
Loa Loa (eye worm) diacylglycerol acyltransferase 0.4584 1 1
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0011 0.0003 0.0003
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.009 0.009
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0012 0.0011
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.009 0.0535
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.009 0.009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0077 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0011 0.0003 0.0002
Brugia malayi ABC transporter family protein 0.001 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0051 0.009 0.009
Onchocerca volvulus 0.0051 0.009 0.0535
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0059 0.0106 0.064
Onchocerca volvulus 0.0051 0.009 0.0535
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0057 0.0103 0.0615
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0034 0.0034
Brugia malayi MH1 domain containing protein 0.0014 0.0009 0.0009
Brugia malayi MH1 domain containing protein 0.0014 0.0009 0.0009
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 0.2426
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.009 0.009
Brugia malayi ecdysone receptor 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0011 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis abcb9, putative 0.001 0.0001 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0027 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0003 0.0003
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0044 0.0074 0.0074
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0027 0.0027
Onchocerca volvulus 0.0051 0.009 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus granulosus peregrin 0.0035 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0377 0.2265
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0133 0.0798
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0095 0.0187 0.0187
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0012 0.0012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0024 0.0146
Echinococcus multilocularis protein dispatched 1 0.0055 0.0099 0.0099
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0287 0.0287
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0011 0.0003 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0161 0.0331 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0027 0.0027
Loa Loa (eye worm) beta-lactamase 0.0071 0.0133 0.0133
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0024 0.018
Echinococcus multilocularis orexin receptor type 2 0.0051 0.009 0.009
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.0003 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.002 0.015
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0017
Brugia malayi neuropeptide F receptor 0.0051 0.009 0.009
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0063 0.0063
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0077 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0554 0.3333
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0133 0.0798
Trichomonas vaginalis ABC transporter, putative 0.001 0.0001 0.0006
Schistosoma mansoni zinc finger protein 0.0771 0.1663 0.1663
Brugia malayi PHD-finger family protein 0.003 0.0043 0.0043
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0012 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0093 0.0093
Schistosoma mansoni neuropeptide receptor 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.009 0.009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0052
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.009 0.009
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0024 0.0663
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0011 0.0003 0.0003
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0011 0.0003 0.0021
Brugia malayi nuclear receptor NHR-67 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0155 0.0317 0.0317
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0001 0.0001
Echinococcus granulosus hypothetical protein 0.0058 0.0105 0.0105
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0038 0.0228
Schistosoma mansoni ferritin 0.0017 0.0015 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.0949 0.2054 0.2054
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0059 0.0106 0.0106
Schistosoma mansoni amine GPCR 0.0051 0.009 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0047 0.0081 0.0081
Leishmania major glycerol uptake protein, putative 0.0771 0.1663 1
Echinococcus multilocularis g protein coupled receptor 0.0051 0.009 0.009
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0027 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Brugia malayi mbt repeat family protein 0.0057 0.0103 0.0103
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0011 0.0003 0.0021
Brugia malayi Serotonin receptor 0.3832 0.8356 0.8356
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0229 0.0479 0.0479
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0053 0.0095 0.0552
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0301 0.0301
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0065 0.012 0.012
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.009 0.009
Loa Loa (eye worm) hhat protein 0.0771 0.1663 0.1663
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus multilocularis sterol O acyltransferase 1 0.0771 0.1663 0.1663
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0038 0.0266
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.002 0.015
Brugia malayi MH2 domain containing protein 0.0373 0.0793 0.0793
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.013
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Brugia malayi Dopamine receptor protein 1 0.0051 0.009 0.009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0302 0.0638 0.0638
Echinococcus granulosus fmrfamide receptor 0.0051 0.009 0.009
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0188 0.0188
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0051 0.009 0.009
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0065 0.012 0.012
Onchocerca volvulus 0.0051 0.009 0.0535
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0024 0.0146
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0051 0.009 0.009
Onchocerca volvulus Alhambra homolog 0.0029 0.0042 0.0249
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0099 0.0099
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.001 0.0001 0.0006
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0011 0.0003 0.0003
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.009 0.009
Echinococcus granulosus SAM and MBT domain containing protein 0.0057 0.0103 0.0103
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 1
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0003 0.0003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0001 0.0003
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0771 0.1663 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.001 0.0001 0.0001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0027 0.0027
Brugia malayi AKH receptor 0.0051 0.009 0.009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0133 0.0133
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0084 0.0084
Schistosoma mansoni myelin transcription factor 1 myt1 0.0065 0.012 0.012
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.009 0.009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.009 0.009
Brugia malayi CHE-14 protein 0.0048 0.0084 0.0084
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0093 0.0093
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0027 0.0027
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0024 0.0024
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0012 0.0012
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0771 0.1663 0.1663
Schistosoma mansoni amine GPCR 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0024 0.0161
Schistosoma mansoni ferritin 0.0017 0.0015 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0057 0.0103 0.0615
Schistosoma mansoni hypothetical protein 0.0399 0.0852 0.0852
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0011 0.0003 0.0019
Brugia malayi jmjC domain containing protein 0.0096 0.0188 0.0188
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0118 0.0118
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Schistosoma mansoni smad1 5 8 and 0.0025 0.0034 0.0034
Onchocerca volvulus 0.0051 0.009 0.0535
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0041 0.0041
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0094 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Entamoeba histolytica hypothetical protein, conserved 0.0771 0.1663 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0047 0.0081 0.0081
Schistosoma mansoni neuropeptide receptor 0.0051 0.009 0.009
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0012 0.0073
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni zinc finger protein 0.0024 0.0032 0.0032
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.001 0.0001 0.0006
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0023 0.0022
Loa Loa (eye worm) transcription factor SMAD2 0.0373 0.0793 0.0793
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0771 0.1663 0.1663
Onchocerca volvulus 0.0101 0.02 0.1195
Schistosoma mansoni ap endonuclease 0.0021 0.0024 0.0024
Brugia malayi Dopamine receptor 0.0051 0.009 0.009
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0038 0.0266
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0271 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0059 0.0106 0.064
Echinococcus granulosus hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.0001 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0058 0.0347
Entamoeba histolytica P-glycoprotein-2 0.001 0.0001 0.0006
Echinococcus multilocularis expressed conserved protein 0.0106 0.021 0.021
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0208 0.0434 0.3341
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0015 0.0015
Trichomonas vaginalis ABC transporter, half transporter, putative 0.001 0.0001 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0133 0.1017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0027 0.0027
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0011 0.0003 0.0021
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0067 0.0067
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0011 0.0003 0.0019
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0003 0.0003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0056 0.0056
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0011 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0032 0.0047 0.0047
Brugia malayi G protein-coupled receptor 0.0051 0.009 0.009
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.0603 0.1296 1
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0027 0.0027
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.0003 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0027 0.0027
Mycobacterium ulcerans lipase LipD 0.0071 0.0133 0.0999
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0038 0.0285
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.01
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0133 0.0798
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0771 0.1663 0.1663
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0133 0.0798
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0071 0.0133 0.0133
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0101 0.02 0.02
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0027 0.0027
Schistosoma mansoni opsin-like receptor 0.0051 0.009 0.009
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0133 0.1017
Schistosoma mansoni cpg binding protein 0.0028 0.004 0.004
Brugia malayi Melatonin receptor type 1A 0.0051 0.009 0.009
Schistosoma mansoni zinc finger protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0071 0.0133 0.0133
Echinococcus granulosus peptidase Clp S14 family 0.0102 0.02 0.02
Schistosoma mansoni smad1 5 8 and 0.0025 0.0034 0.0034
Brugia malayi Hhat protein 0.0771 0.1663 0.1663
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0003 0.0003
Brugia malayi Muscleblind-like protein 0.0179 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.009 0.009
Brugia malayi Probable ClpP-like protease 0.0155 0.0317 0.0317
Onchocerca volvulus 0.0051 0.009 0.0535
Echinococcus granulosus g protein coupled receptor 0.0051 0.009 0.009
Echinococcus granulosus multidrug resistance protein 1 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0024 0.0024
Leishmania major aldehyde dehydrogenase, putative 0.0011 0.0003 0.0015
Schistosoma mansoni hypothetical protein 0.0095 0.0187 0.0187
Brugia malayi MBOAT family protein 0.0771 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis geminin 0.0668 0.1439 0.1439
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0012 0.0012
Schistosoma mansoni bromodomain containing protein 0.0067 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0042
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0011 0.0002 0.0015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0081 0.0081
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni histamine h1 receptor 0.0051 0.009 0.009
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.009 0.009
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0004 0.0004
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0012 0.0011
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0011 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Brugia malayi MH1 domain containing protein 0.0025 0.0034 0.0034
Trypanosoma cruzi GUP1, putative 0.0771 0.1663 1
Echinococcus multilocularis cpg binding protein 0.0032 0.0047 0.0047
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0771 0.1663 0.1663
Loa Loa (eye worm) aldehyde dehydrogenase 0.0011 0.0003 0.0003
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0187 0.0187
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0001 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0038 0.0266
Leishmania major hypothetical protein, conserved 0.0053 0.0094 0.0558
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.009 0.009
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0003 0.0003
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0001 0.0001
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0011 0.0003 0.0015
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.009 0.009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.009 0.009
Brugia malayi nuclear receptor RXR 0.0012 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0554 0.3333
Schistosoma mansoni hypothetical protein 0.0055 0.0099 0.0099
Onchocerca volvulus 0.0051 0.009 0.0535
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.009 0.009
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0003 0.0002
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0023 0.0691
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0027 0.0027
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0001 0.0001
Mycobacterium leprae Probable lipase LipE 0.0071 0.0133 0.0999
Entamoeba histolytica hypothetical protein 0.0771 0.1663 1
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni fkbp-rapamycin associated protein 0.001 0.0000000027257 0.0000000027257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.009 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0027 0.0027
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.4584 1 1
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0053 0.0095 0.0709
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.009 0.009
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0017 0.01
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.009 0.009
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0771 0.1663 0.1663
Echinococcus multilocularis allatostatin A receptor 0.0051 0.009 0.009
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 0.0316
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0017 0.0095
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0206 0.0429 0.0429
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0771 0.1663 0.1663
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0113 0.0225 0.1355
Schistosoma mansoni amine GPCR 0.0051 0.009 0.009
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0027 0.0027
Echinococcus granulosus sterol O acyltransferase 1 0.0771 0.1663 0.1663
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0011 0.0003 0.0021
Toxoplasma gondii ABC1 family protein 0.0071 0.0133 0.0133
Leishmania major aldehyde dehydrogenase, putative 0.0011 0.0003 0.0015
Entamoeba histolytica hypothetical protein 0.0113 0.0225 0.1355
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.009 0.009
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0011 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0179 0.0369 0.0369
Leishmania major glycerol uptake protein, putative 0.0771 0.1663 1
Echinococcus granulosus tumor protein p63 0.0691 0.149 0.149
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0225 0.0225
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.0001 0.0001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0187 0.0187
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0042 0.0042
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0011 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0377 0.2265
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0077 0.0076
Trypanosoma cruzi glycerol uptake protein, putative 0.0771 0.1663 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus granulosus muscleblind protein 0.0179 0.0369 0.0369
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0007 0.0007
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0771 0.1663 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.004 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0038 0.0266
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0771 0.1663 1
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0003 0.0003
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.009 0.009
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0187 0.0187
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0084 0.0507
Toxoplasma gondii aldehyde dehydrogenase 0.0208 0.0434 0.0434
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0771 0.1663 0.1663
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0027 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.002 0.015
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0027 0.0027
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0015 0.0086
Brugia malayi beta-lactamase family protein 0.0071 0.0133 0.0133
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0017 0.01
Echinococcus granulosus cpg binding protein 0.0032 0.0047 0.0047
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0011 0.0003 0.0003
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0771 0.1663 0.1663
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.009 0.009
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0042 0.0042
Trichomonas vaginalis ABC transporter, half transporter, putative 0.001 0.0001 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0027 0.0027
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi MBOAT family protein 0.0771 0.1663 0.1663
Schistosoma mansoni biogenic amine receptor 0.0051 0.009 0.009
Brugia malayi jmjC domain containing protein 0.0039 0.0063 0.0063
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0113 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0071 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0071 0.0133 0.0133
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.003 0.003
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Echinococcus granulosus g-protein coupled receptor 0.0051 0.009 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.009 0.009
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0034 0.0034
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0038 0.0266
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0064 0.0385
Loa Loa (eye worm) hypothetical protein 0.0065 0.012 0.012
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.4584 1 1
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0027 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0094 0.0093
Brugia malayi G-protein coupled receptor 0.0051 0.009 0.009
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0113 0.0225 0.0225
Echinococcus multilocularis protein patched 0.0048 0.0084 0.0084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0048 0.0084 0.0084
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.009 0.009
Onchocerca volvulus 0.0027 0.0038 0.0222
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.0852 0.0852
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Entamoeba histolytica P-glycoprotein 5, putative 0.001 0.0001 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0208 0.0434 0.3328
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.009 0.009
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0017
Echinococcus granulosus neuropeptide receptor A26 0.0949 0.2054 0.2054
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0012 0.0067
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.001 0.0001 0.0001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.009 0.009
Onchocerca volvulus 0.0051 0.009 0.0535
Loa Loa (eye worm) DR-78 0.0011 0.0001 0.0001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0027 0.0027
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0012 0.0012
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0051 0.009 0.009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.002 0.015
Onchocerca volvulus 0.0028 0.004 0.0233
Trichomonas vaginalis abcb9, putative 0.001 0.0001 0.0006
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0208 0.0434 0.0434
Brugia malayi nuclear hormone receptor 0.0022 0.0027 0.0027
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.009 0.009
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni cpg binding protein 0.0032 0.0047 0.0047
Loa Loa (eye worm) mbt repeat family protein 0.0057 0.0103 0.0103
Schistosoma mansoni ferritin 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0038
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0771 0.1663 0.1663
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0011 0.0003 0.0021
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0059 0.0106 0.064
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.009 0.009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0187 0.0187
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0038
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0011 0.0003 0.0021
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0017 0.0017
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0012 0.0086
Schistosoma mansoni ferritin light chain 0.0017 0.0015 0.0015
Trypanosoma cruzi glycerol uptake protein, putative 0.0771 0.1663 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0373 0.0793 0.0793
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0027 0.0027
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0015 0.0067
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0093 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0171 0.1026
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0038 0.0222
Loa Loa (eye worm) hypothetical protein 0.005 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Echinococcus granulosus Niemann Pick C1 protein 0.0161 0.0331 0.0331
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0025 0.0025
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.0003 0.0015
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0001 0.0001
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0155 0.0317 0.189
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0038 0.0228
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0771 0.1663 0.1663
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0155 0.0317 0.0317
Schistosoma mansoni smad 0.0025 0.0034 0.0034
Schistosoma mansoni apoferritin-2 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0554 0.3333
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0011 0.0003 0.0021
Onchocerca volvulus 0.0011 0.0001 0.0003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0027 0.0027
Brugia malayi RE15519p 0.0051 0.009 0.009
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0094 0.0563
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.009 0.009
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0042 0.0042
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0133 0.0133
Brugia malayi Calcitonin receptor-like protein seb-1 0.0302 0.0638 0.0638
Schistosoma mansoni microtubule-associated protein tau 0.0678 0.1462 0.1462
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0102 0.02 0.154
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0106 0.0106
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0015 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0027 0.0027
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0053 0.0095 0.0094
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0771 0.1663 0.1663
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.009 0.009
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.4584 1 1
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis g protein coupled receptor 0.0051 0.009 0.009
Trichomonas vaginalis ferritin, putative 0.0017 0.0015 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Onchocerca volvulus 0.0771 0.1663 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0771 0.1663 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0015 0.0105
Loa Loa (eye worm) acetyltransferase 0.0148 0.0301 0.0301
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0001 0.0003
Leishmania major protein kinase, putative 0.0059 0.0106 0.0634
Onchocerca volvulus 0.0237 0.0496 0.298
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0187 0.0187
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0042 0.0042
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0045 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0133 0.0798
Mycobacterium ulcerans hypothetical protein 0.0071 0.0133 0.0999
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.0003 0.0021
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.009 0.009
Brugia malayi mbt repeat family protein 0.0057 0.0103 0.0103
Brugia malayi Dopamine receptor protein 2 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Trichomonas vaginalis porcupine, putative 0.0771 0.1663 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0011
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.001 0.0001 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0027 0.0027
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0038 0.0222
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0011 0.0003 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0038 0.0038
Giardia lamblia GTOR 0.0018 0.0017 0.1285
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0015
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0027 0.0027
Brugia malayi MH2 domain containing protein 0.0011 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0225 0.0225
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.011 0.011
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.009 0.009
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.009 0.009
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0095
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0003
Schistosoma mansoni patched 1 0.0048 0.0084 0.0084
Brugia malayi tailless protein 0.0011 0.0001 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0024 0.0125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0093 0.0093
Echinococcus granulosus g protein coupled receptor 0.0051 0.009 0.009
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.0225 0.0225
Plasmodium vivax SET domain protein, putative 0.003 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0155 0.0317 0.0317
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0011 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0051 0.009 0.009
Brugia malayi G-protein coupled receptor 0.0051 0.009 0.009
Schistosoma mansoni sex comb on midleg homolog 0.0057 0.0103 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0003 0.0003
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.001 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.0095 0.0187 0.0187
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.0225 0.0225
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0012 0.0012
Brugia malayi nuclear receptor NHR-88 0.0011 0.0001 0.0001
Schistosoma mansoni ap endonuclease 0.0021 0.0024 0.0024
Entamoeba histolytica P-glycoprotein-2 0.001 0.0001 0.0006
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0034 0.0034
Loa Loa (eye worm) multidrug resistance protein 3 0.001 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0011 0.0003 0.0003
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0007 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0133 0.0132
Brugia malayi Bromodomain containing protein 0.0079 0.0151 0.0151
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.001 0.0001 0.0001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0118 0.0118
Onchocerca volvulus 0.0071 0.0133 0.0792
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.009 0.009
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.009 0.0535
Onchocerca volvulus 0.0055 0.0099 0.0592
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0027 0.0027
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.009 0.009
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0145 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Loa Loa (eye worm) MBOAT family protein 0.0771 0.1663 0.1663
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.009 0.009
Brugia malayi Smad1 0.0025 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0038
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.001 0.0001 0.0006
Schistosoma mansoni nuclear receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0133 0.0798
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Echinococcus granulosus neuropeptide receptor 0.0051 0.009 0.009
Schistosoma mansoni multidrug resistance protein 0.001 0.0001 0.0001
Echinococcus granulosus expressed conserved protein 0.0106 0.021 0.021
Brugia malayi hypothetical protein 0.0051 0.009 0.009
Echinococcus multilocularis muscleblind protein 1 0.0179 0.0369 0.0369
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0356 0.2142
Brugia malayi beta-lactamase family protein 0.0071 0.0133 0.0133
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0011 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0017
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.4584 1 1
Trypanosoma cruzi ISWI complex protein 0.0015 0.0011 0.0068
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus granulosus histone acetyltransferase MYST2 0.0065 0.012 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0771 0.1663 1
Schistosoma mansoni aldehyde dehydrogenase 0.0208 0.0434 0.0434
Schistosoma mansoni smad 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0015 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.009 0.009
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.009 0.009
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0017 0.01
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.01
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0001 0.0001
Trypanosoma cruzi GUP1, putative 0.0771 0.1663 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.009 0.009
Entamoeba histolytica P-glycoprotein-2, putative 0.001 0.0001 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0554 0.3333
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0027 0.0159
Schistosoma mansoni smdr2 0.001 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0059 0.0106 0.0106
Schistosoma mansoni hypothetical protein 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0024 0.0024
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0071 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni nuclear receptor 0.0011 0.0001 0.0001
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0027 0.0159
Leishmania major glycerol uptake protein, putative 0.0771 0.1663 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0267 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.009 0.009
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.009 0.009
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.0554 0.3333
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0015 0.0355
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0063 0.0063
Echinococcus multilocularis zinc finger protein 0.0024 0.0032 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0003 0.0003
Schistosoma mansoni apoferritin-2 0.0017 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0071 0.0133 0.0792
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0133 0.1017
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.009 0.009
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0059 0.0106 0.064
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.01
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.009
Brugia malayi Pre-SET motif family protein 0.003 0.0045 0.0045
Plasmodium falciparum diacylglycerol O-acyltransferase 0.4584 1 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0059 0.0106 0.064
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0015 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0063 0.0063
Trypanosoma brucei glycerol uptake protein, putative 0.0771 0.1663 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.009 0.009

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 3.87 ug ml-1 Cytotoxicity against mouse P388 cells after 3 days by MTT assay ChEMBL. No reference
ED50 (functional) = 15.74 ug ml-1 Cytotoxicity against human A549 cells after 6 days by MTT assay ChEMBL. No reference
ED50 (functional) = 16.07 ug ml-1 Cytotoxicity against human HT29 cells after 6 days by MTT assay ChEMBL. No reference
ED50 (functional) > 50 ug ml-1 Cytotoxicity against human KB cells after 3 days by MTT assay ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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