Detailed information for compound 1033122

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 368.903 | Formula: C21H25ClN4
  • H donors: 1 H acceptors: 2 LogP: 4.51 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(Cc1ccccc1)CCCNc1ccc(nn1)c1ccccc1.Cl
  • InChi: 1S/C21H24N4.ClH/c1-25(17-18-9-4-2-5-10-18)16-8-15-22-21-14-13-20(23-24-21)19-11-6-3-7-12-19;/h2-7,9-14H,8,15-17H2,1H3,(H,22,24);1H
  • InChiKey: NNHYJZAGKKPICP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Torpedo californica Acetylcholinesterase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K01049 acetylcholinesterase [EC3.1.1.7], putative Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) carboxylesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum Acetylcholinesterase 1 precursor, putative Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) acetylcholinesterase 1 Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Acetylcholinesterase   586 aa 564 aa 29.4 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   586 aa 546 aa 29.3 %
Onchocerca volvulus Carnitine O-palmitoyltransferase 2, mitochondrial homolog Acetylcholinesterase   586 aa 552 aa 37.7 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   586 aa 509 aa 24.8 %
Onchocerca volvulus Acetylcholinesterase   586 aa 612 aa 25.5 %
Echinococcus granulosus BC026374 protein S09 family Acetylcholinesterase   586 aa 648 aa 32.6 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   586 aa 571 aa 25.0 %
Echinococcus multilocularis BC026374 protein (S09 family) Acetylcholinesterase   586 aa 643 aa 32.2 %
Echinococcus granulosus neuroligin Acetylcholinesterase   586 aa 493 aa 21.5 %
Drosophila melanogaster CG10175 gene product from transcript CG10175-RE Acetylcholinesterase   586 aa 535 aa 31.4 %
Onchocerca volvulus Molybdopterin synthase catalytic subunit homolog Acetylcholinesterase   586 aa 588 aa 28.1 %
Onchocerca volvulus Putative nuclear protein Acetylcholinesterase   586 aa 551 aa 40.7 %
Schistosoma japonicum ko:K01050 cholinesterase [EC3.1.1.8], putative Acetylcholinesterase   586 aa 577 aa 33.6 %
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Acetylcholinesterase   586 aa 602 aa 24.4 %
Schistosoma mansoni gliotactin Acetylcholinesterase   586 aa 474 aa 31.6 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   586 aa 592 aa 28.0 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   586 aa 480 aa 24.6 %
Echinococcus multilocularis neuroligin Acetylcholinesterase   586 aa 487 aa 23.0 %
Onchocerca volvulus Acetylcholinesterase   586 aa 562 aa 25.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0047 0.0102 0.0327
Loa Loa (eye worm) jmjC domain-containing protein 0.0137 0.0382 0.1234
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0065 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0083 0.0411
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0011 0.0015
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0059 0.0085
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0133 0.0371 0.0764
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0028 0.0085
Schistosoma mansoni hypothetical protein 0.0195 0.0563 0.116
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0027 0.0085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0056 0.0115
Loa Loa (eye worm) hypothetical protein 0.0047 0.0102 0.0327
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.003 0.0029
Onchocerca volvulus 0.0062 0.0148 0.0461
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0472 0.143 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Onchocerca volvulus Putative organic anion transporter 0.0128 0.0354 0.113
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0024 0.003 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Entamoeba histolytica P-glycoprotein-2 0.0024 0.003 0.0093
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.003 0.0146
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0392
Schistosoma mansoni cpg binding protein 0.0065 0.0157 0.0324
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0155 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0116 0.0315 0.0463
Echinococcus granulosus neuroligin 0.0021 0.0019 0.0037
Echinococcus multilocularis acetylcholinesterase 0.0123 0.0338 0.0337
Schistosoma mansoni multidrug resistance protein 0.0024 0.003 0.006
Onchocerca volvulus 0.0035 0.0065 0.0192
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0039 0.0268
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.003 0.0043
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Giardia lamblia Kinase, CMGC MAPK 0.0116 0.0315 0.1396
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0148 0.0147
Schistosoma mansoni DNA helicase recq1 0.0027 0.0038 0.0076
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0155 0.0154
Schistosoma mansoni intermediate filament proteins 0.0023 0.0027 0.0054
Echinococcus granulosus muscleblind protein 0.0339 0.1012 0.2089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Mycobacterium ulcerans lipase LipD 0.0041 0.0083 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0044 0.0064
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0039 0.0056
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0073 0.0202
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0011 0.0054
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0008 0.0007
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0017 0.0158
Trichomonas vaginalis esterase, putative 0.0041 0.0083 0.0411
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0016
Brugia malayi intermediate filament protein 0.0023 0.0027 0.0085
Brugia malayi jmjC domain containing protein 0.0133 0.0371 0.1196
Toxoplasma gondii transporter, major facilitator family protein 0.0128 0.0354 0.3351
Onchocerca volvulus 0.0047 0.0102 0.0312
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Loa Loa (eye worm) ICD-1 protein 0.004 0.0079 0.0255
Leishmania major hypothetical protein, conserved 0.0036 0.0065 0.0095
Trypanosoma brucei transcription factor BTF3, putative 0.004 0.0079 0.0116
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0027 0.0038 0.0037
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0119
Echinococcus granulosus cathepsin l1 0.0024 0.0028 0.0056
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Toxoplasma gondii NAC domain-containing protein 0.004 0.0079 0.0746
Entamoeba histolytica transcription factor BTF3, putative 0.004 0.0079 0.034
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0039 0.0108
Brugia malayi Smad1 0.0017 0.0008 0.0023
Echinococcus multilocularis smad 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0017 0.0006 0.0011
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0297 0.0881 0.2849
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0155 0.2373
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0472 0.143 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0148 0.0475
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Entamoeba histolytica cysteine protease, putative 0.0035 0.0065 0.0267
Schistosoma mansoni coup transcription factor 0.0062 0.0148 0.0303
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0155 0.0319
Onchocerca volvulus 0.0035 0.0065 0.0192
Echinococcus multilocularis lysine specific demethylase 5A 0.0133 0.0371 0.037
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0079 0.0199 0.041
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0213 0.0619 1
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0065 0.0132
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0027 0.0085
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0017 0.0017
Toxoplasma gondii cathepsin CPL 0.0035 0.0065 0.0606
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Loa Loa (eye worm) hypothetical protein 0.0123 0.0338 0.1089
Entamoeba histolytica P-glycoprotein-1 0.0024 0.003 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Echinococcus multilocularis caspase 8 0.002 0.0017 0.0017
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0027 0.0038 0.0187
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0746 0.241
Echinococcus granulosus geminin 0.0195 0.0563 0.116
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Echinococcus granulosus cpg binding protein 0.0069 0.0169 0.0347
Onchocerca volvulus 0.0065 0.0157 0.0492
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0038 0.0072 0.0105
Echinococcus granulosus microtubule associated protein 2 0.1565 0.4843 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.078 0.2193
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0148 0.0475
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Entamoeba histolytica recQ family helicase, putative 0.003 0.0046 0.0176
Schistosoma mansoni rab6-interacting 0.0064 0.0155 0.0319
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0017 0.0035
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0087 0.0242
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0148 0.0303
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0213 0.0619 0.1739
Echinococcus granulosus mitogen activated protein kinase 0.0116 0.0315 0.0649
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0054
Trypanosoma brucei mitochondrial DNA polymerase beta 0.2188 0.6789 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0039 0.0056
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0157 0.0507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0011 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0376 0.0553
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0103 0.0103
Echinococcus granulosus Ankyrin 0.0017 0.0006 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0066 0.0614
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.2188 0.6789 1
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0148 0.0303
Echinococcus multilocularis caspase 0.002 0.0017 0.0017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0021 0.0041
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0006 0.001
Brugia malayi hypothetical protein 0.0029 0.0044 0.0141
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0128 0.0354 0.1144
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0103 0.0332
Echinococcus multilocularis lamin 0.0023 0.0027 0.0026
Schistosoma mansoni transcription factor btf3 0.004 0.0079 0.0163
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0148 0.0475
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Onchocerca volvulus 0.0024 0.0028 0.0073
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0027 0.0038 0.0076
Onchocerca volvulus 0.0029 0.0045 0.0129
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0065 0.0094
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Echinococcus multilocularis mitogen activated protein kinase 0.0116 0.0315 0.0314
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0148 0.0461
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0021 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0148 0.0303
Mycobacterium ulcerans carboxylesterase, LipT 0.0021 0.0019 0.0051
Schistosoma mansoni cpg binding protein 0.0069 0.0169 0.0347
Plasmodium vivax vivapain-2 0.0035 0.0065 0.0884
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Echinococcus granulosus acetylcholinesterase 0.0123 0.0338 0.0695
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Schistosoma mansoni retinoic acid receptor RXR 0.0175 0.0502 0.1035
Treponema pallidum fructose-bisphosphate aldolase 0.0663 0.2025 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.1035 0.3189 0.4696
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0039 0.0056
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0148 0.0461
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Leishmania major NAD synthase, putative 0.0094 0.0249 0.0366
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0148 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0148 0.0475
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0038 0.0072 0.0429
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0083 0.0411
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0065 0.0133
Toxoplasma gondii Alpha-galactosidase 0.0017 0.0006 0.005
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.003 0.0319
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0116 0.0315 0.0463
Schistosoma mansoni hypothetical protein 0.0195 0.0563 0.116
Plasmodium vivax metacaspase 1, putative 0.002 0.0017 0.0107
Schistosoma mansoni hypothetical protein 0.0928 0.2852 0.5888
Schistosoma mansoni inositol monophosphatase 0.0042 0.0087 0.0177
Echinococcus granulosus smad 0.0017 0.0008 0.0015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0039 0.0108
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0426 0.1375
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi hypothetical protein 0.0064 0.0155 0.05
Schistosoma mansoni organic anion transporter 0.0128 0.0354 0.073
Brugia malayi SPARC precursor 0.0088 0.0227 0.0733
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0148 0.0303
Brugia malayi Pre-SET motif family protein 0.0036 0.0066 0.021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0065 0.0133
Schistosoma mansoni survival motor neuron protein 0.0055 0.0127 0.0261
Onchocerca volvulus Huntingtin homolog 0.0106 0.0285 0.0907
Echinococcus granulosus cathepsin L 0.0018 0.0011 0.0021
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0045 0.0092
Schistosoma mansoni hypothetical protein 0.0103 0.0277 0.057
Schistosoma mansoni acetylcholinesterase 0.0021 0.0019 0.0037
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0155 0.0154
Schistosoma mansoni multidrug resistance protein 0.0024 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0148 0.0303
Echinococcus multilocularis transcription factor btf3 0.004 0.0079 0.0079
Trichomonas vaginalis DNA helicase recq, putative 0.003 0.0046 0.0229
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Schistosoma mansoni smad1 5 8 and 0.0017 0.0008 0.0015
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0815 0.2499 0.2499
Loa Loa (eye worm) hypothetical protein 0.0068 0.0165 0.0533
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0083 0.0267
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0059 0.0187
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0044 0.0414
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0011 0.0033
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0087 0.0813
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0123 0.0338 0.0695
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Brugia malayi multidrug resistance protein 3 0.0024 0.003 0.0094
Toxoplasma gondii melibiase subfamily protein 0.0118 0.0322 0.3042
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0148 0.0475
Loa Loa (eye worm) glutaminase 0.0314 0.0936 0.3024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0148 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Echinococcus multilocularis mitogen activated protein kinase 3 0.0116 0.0315 0.0314
Brugia malayi MH2 domain containing protein 0.0017 0.0008 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0045 0.0092
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0376 0.0553
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0088
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0057 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0011 0.0015
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0375 0.1125 0.1657
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0083 0.0232
Loa Loa (eye worm) carboxylesterase 0.0021 0.0019 0.0058
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0119
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0079 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0148 0.0475
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0128 0.0354 0.073
Onchocerca volvulus 0.0021 0.0019 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Leishmania major cathepsin L-like protease 0.0135 0.0376 0.0553
Echinococcus granulosus Solute carrier organic anion transporter family 0.0128 0.0354 0.073
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0308 0.0915 0.1347
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0066 0.0134
Schistosoma mansoni lozenge 0.0126 0.0348 0.0716
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0128 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0011 0.0015
Echinococcus multilocularis BC026374 protein (S09 family) 0.0021 0.0019 0.0018
Brugia malayi cathepsin L-like precursor 0.0024 0.0028 0.0088
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0065 0.0133
Leishmania major basic transcription factor 3a, putative 0.004 0.0079 0.0116
Plasmodium vivax vivapain-2 0.0035 0.0065 0.0884
Schistosoma mansoni hypothetical protein 0.0041 0.0083 0.017
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0021 0.0019 0.0037
Echinococcus multilocularis para nitrobenzyl esterase 0.0021 0.0019 0.0018
Plasmodium vivax JmjC domain containing protein 0.0036 0.0065 0.089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0257 0.0827
Brugia malayi Cell death protein 3 precursor 0.0068 0.0165 0.0533
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0148 0.0475
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0124
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Onchocerca volvulus 0.0021 0.0019 0.0043
Schistosoma mansoni lipoxygenase 0.0252 0.0743 0.1532
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0017 0.0025
Onchocerca volvulus Cell death protein 3 homolog 0.0068 0.0165 0.0518
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0065 0.0064
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Mycobacterium tuberculosis Conserved protein 0.0041 0.0083 0.0232
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0083 0.017
Brugia malayi Cytochrome P450 family protein 0.0034 0.0059 0.0187
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0017 0.0007 0.0033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Brugia malayi hypothetical protein 0.0021 0.0019 0.0058
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0006 0.0016
Loa Loa (eye worm) inositol-1 0.0042 0.0087 0.0278
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0218 0.0449
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0045 0.0092
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Brugia malayi hypothetical protein 0.1005 0.3092 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0103 0.0332
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0083 0.0122
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0155 0.0154
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0148 0.0303
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Echinococcus granulosus lamin 0.0023 0.0027 0.0054
Echinococcus granulosus BC026374 protein S09 family 0.0021 0.0019 0.0037
Brugia malayi Cytochrome P450 family protein 0.0034 0.0059 0.0187
Brugia malayi hypothetical protein 0.0041 0.0083 0.0267
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0148 0.0303
Brugia malayi hypothetical protein 0.0106 0.0285 0.0921
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0065 0.0267
Schistosoma mansoni hypothetical protein 0.0111 0.0301 0.0619
Mycobacterium tuberculosis Conserved protein 0.0041 0.0083 0.0232
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0039 0.0108
Echinococcus multilocularis pol protein 0.3216 1 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0208
Echinococcus multilocularis cathepsin L 0.0018 0.0011 0.001
Onchocerca volvulus 0.0128 0.0354 0.113
Brugia malayi sodium-independent organic anion transporter family protein 0.0128 0.0354 0.1144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0017
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0028 0.0056
Brugia malayi nuclear receptor RXR 0.0033 0.0056 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0148 0.0475
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0252 0.0743 0.1532
Trypanosoma cruzi NAD+ synthase, putative 0.0094 0.0249 0.0366
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0065 0.0133
Echinococcus granulosus RUN 0.0064 0.0155 0.0319
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0116 0.0315 0.0463
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0213 0.0619 0.4324
Echinococcus multilocularis cysteine protease 0.0035 0.0065 0.0064
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0045 0.0144
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0277 0.0892
Brugia malayi Pre-SET motif family protein 0.0241 0.0706 0.2281
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Trypanosoma brucei metacaspase MCA2 0.002 0.0017 0.0025
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0006 0.0005
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0017 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Echinococcus multilocularis neuroligin 0.0021 0.0019 0.0018
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0039 0.0108
Onchocerca volvulus 0.0023 0.0027 0.0069
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Schistosoma mansoni BC026374 protein (S09 family) 0.0021 0.0019 0.0037
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0116 0.0315 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0008
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0155 0.1016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Loa Loa (eye worm) hypothetical protein 0.0106 0.0285 0.0921
Schistosoma mansoni neuroligin 3 (S09 family) 0.0021 0.0019 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0148 0.0475
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0045 0.0129
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0213 0.0619 0.5853
Toxoplasma gondii protease inhibitor PI2 0.0088 0.0227 0.2147
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.0706 0.2281
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0065 0.0207
Toxoplasma gondii histone lysine methyltransferase SET1 0.0125 0.0343 0.3246
Loa Loa (eye worm) hypothetical protein 0.0106 0.0285 0.0921
Schistosoma mansoni smdr2 0.0024 0.003 0.006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0083 0.0082
Brugia malayi prostaglandin transporter 0.0128 0.0354 0.1144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0148 0.0475
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Loa Loa (eye worm) hypothetical protein 0.1005 0.3092 1
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0148 0.0303
Entamoeba histolytica NAD synthetase, putative 0.0094 0.0249 0.1181
Echinococcus multilocularis musashi 0.0023 0.0027 0.0026
Echinococcus multilocularis multidrug resistance protein 1 0.0017 0.0007 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0019 0.0037
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0181 0.0584
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0308 0.0915 0.1347
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0155 0.0319
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0094 0.0249 0.1677
Echinococcus multilocularis dnaJ subfamily B 0.0928 0.2852 0.2852
Schistosoma mansoni caspase-7 (C14 family) 0.0068 0.0165 0.034
Brugia malayi hypothetical protein 0.0019 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Onchocerca volvulus 0.0055 0.0127 0.0394
Onchocerca volvulus 0.0035 0.0065 0.0192
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.1035 0.3189 0.4696
Loa Loa (eye worm) hypothetical protein 0.0339 0.1012 0.3272
Schistosoma mansoni zinc finger protein 0.0029 0.0045 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0039 0.0108
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0087 0.0427
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0103 0.0332
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0083 0.0232
Loa Loa (eye worm) DR-78 0.0029 0.0045 0.0144
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.0339 0.0499
Plasmodium vivax basic transcription factor 3b, putative 0.004 0.0079 0.1128
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0339 0.1012 0.3272
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Echinococcus granulosus acetylcholinesterase 0.0123 0.0338 0.0695
Echinococcus granulosus caspase 0.002 0.0017 0.0035
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0008 0.0023
Brugia malayi MH1 domain containing protein 0.0017 0.0008 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0056 0.018
Leishmania major hypothetical protein, conserved 0.0041 0.0083 0.0122
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Echinococcus multilocularis pol protein 0.3216 1 1
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0472 0.143 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0045 0.0144
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.003 0.0094
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0094 0.0249 0.1229
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0045 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Mycobacterium ulcerans beta-lactamase 0.0041 0.0083 0.0232
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0018 0.0047
Trichomonas vaginalis hypothetical protein 0.0213 0.0619 0.3055
Trichomonas vaginalis abcb9, putative 0.0024 0.003 0.0146
Brugia malayi secreted modular calcium-binding protein 1 0.0088 0.0227 0.0733
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0595 0.294
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0039 0.0139
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Schistosoma mansoni polycystin 1-related 0.0064 0.0155 0.0319
Echinococcus granulosus cathepsin l1 0.0035 0.0065 0.0132
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0045 0.0144
Plasmodium vivax SET domain protein, putative 0.0036 0.0066 0.0899
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0124
Mycobacterium tuberculosis Conserved protein 0.0041 0.0083 0.0232
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0148 0.0475
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0148 0.0303
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.003 0.0093
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0083 0.0122
Schistosoma mansoni gliotactin 0.0021 0.0019 0.0037
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0065 0.0095
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0021 0.0065
Schistosoma mansoni smad1 5 8 and 0.0017 0.0008 0.0015
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0065 0.0133
Brugia malayi nuclear receptor NHR-67 0.0029 0.0045 0.0144
Echinococcus multilocularis RUN 0.0064 0.0155 0.0154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Plasmodium falciparum basic transcription factor 3b, putative 0.004 0.0079 0.0483
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0045 0.0144
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0148 0.0147
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0065 0.0207
Brugia malayi Doublecortin family protein 0.0064 0.0155 0.05
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0008 0.0015
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0065 0.0609
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0021 0.0019 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0148 0.0475
Echinococcus multilocularis survival motor neuron protein 1 0.0272 0.0803 0.0803
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0148 0.0303
Brugia malayi Bloom's syndrome protein homolog 0.004 0.008 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0066 0.0134
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0038 0.0072 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0148 0.0475
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0046 0.0067
Onchocerca volvulus 0.0021 0.0019 0.0043
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0213 0.0619 0.3961
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0746 0.241
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0181 0.0181
Echinococcus multilocularis Protein lozenge 0.0126 0.0348 0.0347
Mycobacterium ulcerans hypothetical protein 0.0027 0.0039 0.0108
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0024 0.0029 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0018 0.0108
Leishmania major cytochrome p450-like protein 0.0034 0.0059 0.0085
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0083 0.0411
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Brugia malayi jmjC domain containing protein 0.0137 0.0382 0.1234
Echinococcus granulosus GPCR family 2 0.0048 0.0103 0.0212
Brugia malayi ecdysone receptor 0.0029 0.0045 0.0144
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0059 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0148 0.0475
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0044 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Trypanosoma brucei metacaspase 5, putative 0.002 0.0017 0.0025
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0019 0.0037
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0065 0.0095
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0116 0.0315 0.0463
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus multilocularis expressed protein 0.0088 0.0227 0.0227
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0008 0.0023
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0038 0.0072 0.0105
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0472 0.143 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0083 0.0411
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0181 0.0584
Echinococcus multilocularis GPCR, family 2 0.0048 0.0103 0.0103
Loa Loa (eye worm) acetylcholinesterase 1 0.0123 0.0338 0.1089
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0148 0.0475
Schistosoma mansoni lipoxygenase 0.0137 0.038 0.0784
Echinococcus multilocularis acetylcholinesterase 0.0123 0.0338 0.0337
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0083 0.017
Loa Loa (eye worm) hypothetical protein 0.1005 0.3092 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0103 0.0212
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0472 0.143 0.4021
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0017 0.0035
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0148 0.0147
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0011 0.0015
Schistosoma mansoni microtubule-associated protein tau 0.1565 0.4843 1
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Trichomonas vaginalis taga, putative 0.0024 0.003 0.0146
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0045 0.0144
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0091
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0017 0.0158
Echinococcus multilocularis pol protein 0.3216 1 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0017 0.0158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0261
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0083 0.0232
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.003 0.0132
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0127 0.0409
Loa Loa (eye worm) carboxylesterase 0.0021 0.0019 0.0058
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0044 0.0236
Mycobacterium tuberculosis Conserved hypothetical protein 0.1152 0.3554 1
Onchocerca volvulus 0.0128 0.0354 0.113
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0208
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0083 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0011 0.0015
Loa Loa (eye worm) cysteine protease 0.0035 0.0065 0.0207
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.003 0.0094
Loa Loa (eye worm) agrin synaptic family protein 0.0088 0.0227 0.0733
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0065 0.0133
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0027 0.0038 0.0119
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Leishmania major metacaspase, putative 0.002 0.0017 0.0025
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0046 0.0067
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0213 0.0619 0.1739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0087 0.0427
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0116 0.0315 0.0463
Schistosoma mansoni cpg binding protein 0.0069 0.0169 0.0347
Schistosoma mansoni smad1 5 8 and 0.0017 0.0008 0.0015
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Brugia malayi Uncoordinated protein 44 0.0017 0.0006 0.0016
Brugia malayi ecdysteroid receptor 0.0062 0.0148 0.0475
Mycobacterium ulcerans hypothetical protein 0.1152 0.3554 1
Mycobacterium ulcerans NAD synthetase 0.0094 0.0249 0.0698
Loa Loa (eye worm) hypothetical protein 0.0126 0.0347 0.1119
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Plasmodium falciparum enoyl-acyl carrier reductase 0.0213 0.0619 0.4283
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Loa Loa (eye worm) RecQ helicase 0.004 0.008 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0065 0.0609
Schistosoma mansoni rab6-interacting 0.0064 0.0155 0.0319
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0118 0.0322 0.0321
Brugia malayi hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni follistatin 0.0088 0.0227 0.0468
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0079 0.0199 0.0984
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0083 0.1189
Schistosoma mansoni agrin 0.0088 0.0227 0.0468
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0148 0.0475
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0257 0.0528
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0148 0.0303
Echinococcus multilocularis lamin dm0 0.0023 0.0027 0.0026
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0056 0.0115
Brugia malayi Cytochrome P450 family protein 0.0055 0.0127 0.0408
Plasmodium falciparum metacaspase-like protein 0.002 0.0017 0.0046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0148 0.0303
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0011 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Leishmania major hypothetical protein, conserved 0.0029 0.0044 0.0064
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0045 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0045 0.0092
Onchocerca volvulus Huntingtin homolog 0.0106 0.0285 0.0907
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0066 0.0065
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0065 0.0064
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Echinococcus multilocularis caspase 2 0.0068 0.0165 0.0165
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Echinococcus multilocularis cysteine protease 0.0035 0.0065 0.0064
Echinococcus multilocularis Ankyrin 0.0017 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0151 0.0426 0.1375
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0324 0.0966 0.2715
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0029 0.0265
Trypanosoma brucei protein kinase, putative 0.0116 0.0315 0.0463
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0044 0.0551
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0008 0.0016
Echinococcus granulosus dnaJ subfamily B 0.0928 0.2852 0.5888
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0028 0.0088
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0066 0.0134
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0065 0.0064
Onchocerca volvulus 0.0035 0.0065 0.0192
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0088
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0094 0.0249 0.0698
Loa Loa (eye worm) carboxylesterase 0.0123 0.0338 0.1089
Echinococcus granulosus tar DNA binding protein 0.0073 0.0181 0.0373
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0008 0.0015
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0039 0.0077 0.0076
Onchocerca volvulus Putative organic anion transporter 0.0128 0.0354 0.113
Brugia malayi steroid hormone receptor 0.0062 0.0148 0.0475
Brugia malayi Cathepsin L-like precursor 0.0024 0.0028 0.0088
Brugia malayi Carboxylesterase family protein 0.0123 0.0338 0.1089
Brugia malayi hypothetical protein 0.0033 0.0056 0.018
Brugia malayi nuclear receptor RXR 0.0029 0.0045 0.0144
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Toxoplasma gondii hypothetical protein 0.0353 0.1056 1
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0103 0.0332
Onchocerca volvulus 0.0128 0.0354 0.113
Brugia malayi Death domain containing protein 0.0017 0.0006 0.0016
Echinococcus multilocularis bloom syndrome protein 0.004 0.008 0.0079
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0087 0.0086
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.2188 0.6789 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0045 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0148 0.0475
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0065 0.0208
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0175 0.0502 0.1035
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Onchocerca volvulus 0.0088 0.0227 0.0719
Echinococcus granulosus lamin dm0 0.0023 0.0027 0.0054
Echinococcus multilocularis Smad4 0.0017 0.0008 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0083 0.017
Trypanosoma cruzi NAD+ synthase, putative 0.0094 0.0249 0.0366
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0008 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0257 0.0528
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.002 0.0062
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0148 0.0475
Schistosoma mansoni hypothetical protein 0.0064 0.0155 0.0319
Trypanosoma brucei metacaspase MCA3 0.002 0.0017 0.0025
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0297 0.0881 0.2849
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0257 0.0256
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.003 0.0081
Echinococcus granulosus mitogen activated protein kinase 3 0.0116 0.0315 0.0649
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0039 0.0077 0.0157
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0011 0.0021
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0039 0.0108
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0046 0.0067
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni jumonji/arid domain-containing protein 0.0137 0.0382 0.0788
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0039 0.0124
Onchocerca volvulus 0.0041 0.0083 0.0252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0257 0.0528
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0065 0.0208
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.0064 0.0155 0.05
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0071 0.0425
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0308 0.0915 0.1347
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.003 0.0274
Echinococcus multilocularis geminin 0.0195 0.0563 0.0562
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0083 0.017
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0083 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0065 0.0379
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Leishmania major cathepsin L-like protease 0.0135 0.0376 0.0553
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0065 0.0192
Brugia malayi Cathepsin L-like precursor 0.0024 0.0028 0.0088
Brugia malayi sodium-independent organic anion transporter family protein 0.0128 0.0354 0.1144
Brugia malayi MH1 domain containing protein 0.0017 0.0008 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0044 0.0064
Brugia malayi hypothetical protein 0.0033 0.0056 0.018
Brugia malayi hypothetical protein 0.0064 0.0155 0.05
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0039 0.0139
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0148 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0094 0.0249 0.2351
Echinococcus multilocularis muscleblind protein 0.0339 0.1012 0.1012
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0039 0.0139
Brugia malayi MH2 domain containing protein 0.0253 0.0746 0.241
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0011 0.0033
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0252 0.0743 0.0742
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0392
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Schistosoma mansoni DNA helicase recq5 0.0027 0.0038 0.0076
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0094 0.0249 0.3916
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0083 0.0232
Loa Loa (eye worm) glutaminase 2 0.0314 0.0936 0.3024
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0008 0.0015
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0116 0.0315 0.2977
Brugia malayi hypothetical protein 0.0272 0.0803 0.2596
Brugia malayi Melibiase family protein 0.0079 0.0199 0.0642
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0066 0.0134
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Echinococcus multilocularis cpg binding protein 0.0069 0.0169 0.0168
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0065 0.0132
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0116 0.0315 0.0463
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0059 0.0187
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0155 0.05
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0148 0.0475
Schistosoma mansoni jumonji/arid domain-containing protein 0.0137 0.0382 0.0788
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0139 0.0389 0.0803
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi Muscleblind-like protein 0.0339 0.1012 0.3272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0006 0.0011
Onchocerca volvulus Putative organic anion transporter 0.0128 0.0354 0.113
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0008 0.0008
Brugia malayi TAR-binding protein 0.0073 0.0181 0.0584
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Brugia malayi RNA binding protein 0.0073 0.0181 0.0584
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0027 0.0038 0.0076
Mycobacterium ulcerans hypothetical protein 0.0041 0.0083 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi beta-lactamase family protein 0.0041 0.0083 0.0267
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0181 0.0584
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0006 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0083 0.0411
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0011 0.0021
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0065 0.0132
Brugia malayi beta-lactamase 0.0041 0.0083 0.0267
Echinococcus multilocularis carboxylesterase 5A 0.0123 0.0338 0.0337
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Onchocerca volvulus 0.0064 0.0155 0.0485
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.0376 0.0553
Mycobacterium ulcerans glutaminase 0.0314 0.0936 0.2631
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0045 0.0045
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0065 0.0192
Leishmania major p-glycoprotein 0.0024 0.003 0.0043
Schistosoma mansoni nuclear receptor 0.0029 0.0045 0.0092
Trichomonas vaginalis abcb9, putative 0.0024 0.003 0.0146
Leishmania major cathepsin L-like protease 0.0135 0.0376 0.0553
Brugia malayi GMP synthase 0.0038 0.0072 0.023
Echinococcus granulosus death domain containing protein 0.0017 0.0006 0.001
Brugia malayi glutaminase DH11.1 0.0314 0.0936 0.3024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0065 0.0064
Schistosoma mansoni lamin 0.0023 0.0027 0.0054
Trypanosoma cruzi MFS transporter, putative 0.0128 0.0354 0.0521
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0148 0.0475
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0087 0.0375
Echinococcus granulosus apoptotic protease activating factor 1 0.0047 0.0102 0.0209
Onchocerca volvulus 0.0021 0.0019 0.0043
Schistosoma mansoni lamin 0.0023 0.0027 0.0054
Trichomonas vaginalis abcb9, putative 0.0024 0.003 0.0146
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0039 0.0124
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0143 0.0399 0.0399
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0092
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0148 0.0303
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0123 0.0338 0.1089
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Onchocerca volvulus 0.0035 0.0065 0.0192
Loa Loa (eye worm) hypothetical protein 0.0079 0.0199 0.0642
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.003 0.0093
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Mycobacterium leprae Probable lipase LipE 0.0041 0.0083 0.0577
Entamoeba histolytica hypothetical protein 0.004 0.0079 0.034
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0007 0.0012
Echinococcus multilocularis microtubule associated protein 2 0.1565 0.4843 0.4843
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0028 0.0139
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0059 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0039 0.0108
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0007 0.0012
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0207
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0059 0.0187
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0118 0.0322 0.0663
Plasmodium vivax GMP synthetase, putative 0.0038 0.0072 0.1002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0056 0.0115
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Giardia lamblia NH3-dependent NAD+ synthetase 0.0094 0.0249 0.1064
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0663 0.2025 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Echinococcus granulosus transcription factor btf3 0.004 0.0079 0.0163
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0118 0.0322 0.0321
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0324 0.0966 0.2715
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0094 0.0249 0.0512
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Schistosoma mansoni hypothetical protein 0.0017 0.0006 0.001
Onchocerca volvulus 0.0036 0.0066 0.0194
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0017 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Brugia malayi Inositol-1 0.0042 0.0087 0.0278
Onchocerca volvulus 0.0023 0.0027 0.0069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0208
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0017 0.0054
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0116 0.0315 0.1016
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0308 0.0915 0.1347
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0039 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0148 0.0475
Brugia malayi beta-NAC-like protein 0.004 0.0079 0.0255
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0376 0.0553
Loa Loa (eye worm) fibroinase 0.0035 0.0065 0.0207
Loa Loa (eye worm) hypothetical protein 0.0103 0.0277 0.0892
Mycobacterium ulcerans GMP synthase 0.0038 0.0072 0.02
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0087 0.0177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0028 0.0139
Brugia malayi conserved hypotetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni multidrug resistance protein 0.0024 0.003 0.006
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Onchocerca volvulus 0.1005 0.3092 1
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0011 0.0015
Onchocerca volvulus 0.0128 0.0354 0.113
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0083 0.0232
Brugia malayi tailless protein 0.0029 0.0045 0.0144
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0021 0.0019 0.0092
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0073 0.0503
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0065 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Echinococcus granulosus survival motor neuron protein 1 0.0272 0.0803 0.1657
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0426 0.1375
Schistosoma mansoni inositol monophosphatase 0.0042 0.0087 0.0177
Trypanosoma brucei metacaspase 0.002 0.0017 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Echinococcus multilocularis follistatin 0.0088 0.0227 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Entamoeba histolytica P-glycoprotein-2 0.0024 0.003 0.0093
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0065 0.0132
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.003 0.0029
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0127 0.0408
Entamoeba histolytica P-glycoprotein-5 0.0024 0.003 0.0093
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0045 0.0092
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0087 0.0427
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0065 0.0379
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Echinococcus multilocularis muscleblind protein 1 0.0339 0.1012 0.1012
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0065 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0148 0.0475
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0085
Trichomonas vaginalis spcc417.12 protein, putative 0.0021 0.0019 0.0092
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0065 0.0192
Giardia lamblia Fructose-bisphosphate aldolase 0.0663 0.2025 1
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0056 0.018
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0148 0.0147
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0148 0.0303
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0094 0.0249 0.1737
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0056 0.0056
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0017 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0274 0.0809 0.3996
Onchocerca volvulus 0.0128 0.0354 0.113
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0094
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0079 0.0116
Brugia malayi nuclear receptor NHR-88 0.0062 0.0148 0.0475
Loa Loa (eye worm) hypothetical protein 0.0272 0.0803 0.2596
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0021 0.0019 0.0018
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0038 0.0072 0.0674
Plasmodium falciparum metacaspase 1 0.002 0.0017 0.0046
Echinococcus granulosus follistatin 0.0088 0.0227 0.0468
Toxoplasma gondii ABC1 family protein 0.0041 0.0083 0.0781
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0044 0.0236
Schistosoma mansoni hypothetical protein 0.0047 0.0102 0.0209
Echinococcus granulosus caspase 2 0.0068 0.0165 0.034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0426 0.1375
Trichomonas vaginalis glutaminase, putative 0.0314 0.0936 0.4621
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0065 0.0379
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0257 0.0827
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0056 0.018
Echinococcus granulosus intermediate filament protein 0.0023 0.0027 0.0054
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0083 0.0232
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0141
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Onchocerca volvulus 0.0274 0.081 0.2605
Schistosoma mansoni loxhd1 0.0064 0.0155 0.0319
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0148 0.0147
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0083 0.0577
Entamoeba histolytica P-glyco protein 6, putative 0.0024 0.003 0.0093
Loa Loa (eye worm) RNA binding protein 0.0073 0.0181 0.0584
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Echinococcus granulosus carboxylesterase 5A 0.0123 0.0338 0.0695
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0066 0.0134
Schistosoma mansoni organic anion transporter 0.0128 0.0354 0.073
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0324 0.0966 0.6752
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0595 0.294
Onchocerca volvulus 0.0064 0.0155 0.0485
Brugia malayi MAP kinase sur-1 0.0116 0.0315 0.1016
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0213 0.0619 0.4256
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0079 0.0199 0.041
Echinococcus multilocularis agrin 0.0088 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0045 0.0144
Brugia malayi Protein kinase domain containing protein 0.0018 0.0009 0.0026
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0045 0.0129
Onchocerca volvulus 0.0021 0.0019 0.0043
Schistosoma mansoni nuclear receptor 0.0029 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0065 0.0064
Trypanosoma brucei RNA helicase, putative 0.0111 0.0301 0.0442
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.0286 0.042
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0039 0.0108
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0029 0.0028
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0045 0.0092
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0103 0.0212
Echinococcus granulosus agrin 0.0088 0.0227 0.0468
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0018 0.0047
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0059 0.0085
Onchocerca volvulus Glucosylceramidase homolog 0.0195 0.0562 0.1804
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0065 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0103 0.0103
Echinococcus granulosus lysine specific demethylase 5A 0.0137 0.0382 0.0788
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Loa Loa (eye worm) ctsf protein 0.0035 0.0065 0.0207
Echinococcus multilocularis apoptotic protease activating factor 1 0.0047 0.0102 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0018 0.0046
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Brugia malayi ABC transporter family protein 0.0024 0.003 0.0094
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0065 0.0064
Leishmania major mitochondrial DNA polymerase beta 0.2188 0.6789 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Plasmodium vivax hypothetical protein, conserved 0.002 0.0017 0.0107
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.1035 0.3189 0.4696
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Loa Loa (eye worm) hypothetical protein 0.0064 0.0155 0.05
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.003 0.0307
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0133 0.0371 0.037
Brugia malayi nuclear hormone receptor 0.0062 0.0148 0.0475
Brugia malayi beta-lactamase family protein 0.0041 0.0083 0.0267
Onchocerca volvulus 0.0035 0.0065 0.0192
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0663 0.2025 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0088
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0039 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Schistosoma mansoni GMP synthetase 0.0038 0.0072 0.0147
Onchocerca volvulus 0.0027 0.0039 0.0109
Brugia malayi hypothetical protein 0.0128 0.0354 0.1144
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0065 0.0133
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0065 0.0133
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0027 0.0038 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0148 0.0475
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0083 0.0232
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0045 0.0144
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0065 0.0207
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.003 0.006
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Trypanosoma brucei NAD+ synthase, putative 0.0094 0.0249 0.0366
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0027 0.0085
Brugia malayi CXXC zinc finger family protein 0.0065 0.0157 0.0507
Brugia malayi MH2 domain containing protein 0.0017 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0036
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0472 0.143 0.6649
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0011 0.0021
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0057 0.0131 0.0269
Brugia malayi hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni smad 0.0017 0.0008 0.0015
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0021 0.002
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0148 0.0303
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.008 0.0396
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0039 0.0268
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0038 0.0072 0.0147
Schistosoma mansoni Smad4 0.0017 0.0008 0.0015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0348
Echinococcus granulosus phd:f box containing protein 0.0036 0.0065 0.0133
Loa Loa (eye worm) Smad1 0.0017 0.0008 0.0023
Echinococcus granulosus Smad4 0.0017 0.0008 0.0015
Echinococcus granulosus cysteine protease 0.0018 0.0011 0.0021
Loa Loa (eye worm) beta-lactamase 0.0041 0.0083 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0065 0.0381
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0257 0.0256
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0045 0.0092
Onchocerca volvulus 0.0029 0.0045 0.0129
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.003 0.0274
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0083 0.0232
Onchocerca volvulus 0.0035 0.0065 0.0192
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Echinococcus granulosus caspase 8 0.002 0.0017 0.0035
Loa Loa (eye worm) runx1 0.0126 0.0348 0.1122
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0083 0.017
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0148 0.0303
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.0733
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0045 0.0144
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Onchocerca volvulus 0.0041 0.0083 0.0252
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Schistosoma mansoni glutaminase 0.0314 0.0936 0.1931
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.003 0.0146
Onchocerca volvulus 0.0041 0.0083 0.0252
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0128 0.0354 0.1144
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0128 0.0354 0.0354
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0124
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Mycobacterium tuberculosis Carboxylesterase LipT 0.0021 0.0019 0.0051
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0148 0.0461
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0083 0.0267
Brugia malayi hypothetical protein 0.0128 0.0354 0.1144
Brugia malayi nuclear hormone receptor 0.0029 0.0045 0.0144
Schistosoma mansoni netrin receptor unc5 0.0017 0.0006 0.001
Echinococcus granulosus bloom syndrome protein 0.004 0.008 0.0164
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0038 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0148 0.0303
Trypanosoma brucei Metacaspase-4 0.002 0.0017 0.0025
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0371 0.0764
Echinococcus granulosus para nitrobenzyl esterase 0.0021 0.0019 0.0037
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0083 0.0232
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0008 0.0007
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0119
Brugia malayi Carboxylesterase family protein 0.0123 0.0338 0.1089
Onchocerca volvulus 0.0024 0.003 0.0078
Brugia malayi nuclear receptor NHR-88 0.0029 0.0045 0.0144
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0257 0.0528
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0472 0.143 0.4021
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0065 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0315 0.0649
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0019 0.0037
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.008 0.0396
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0257 0.0528

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 13 uM In vitro inhibition of Torpedo californica acetylcholinesterase. ChEMBL. 10052979

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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