Detailed information for compound 1038891

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 363.801 | Formula: C12H22ClN7O4
  • H donors: 5 H acceptors: 4 LogP: -3.33 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: N[C@H](CC(=O)N(C1CN=C(NC1=O)NC(=O)N)C)CCC(=O)N.Cl
  • InChi: 1S/C12H21N7O4.ClH/c1-19(9(21)4-6(13)2-3-8(14)20)7-5-16-12(17-10(7)22)18-11(15)23;/h6-7H,2-5,13H2,1H3,(H2,14,20)(H4,15,16,17,18,22,23);1H/t6-,7?;/m0./s1
  • InChiKey: GZWJDNUTICCYPY-OXIGJRIQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis importin beta-1, putative 0.0131 0.066 0.4718
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.026 0.0824
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.0214 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0049 0.0292
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0025 0.0085 0.0092
Leishmania major hypothetical protein, conserved 0.0028 0.0101 0.0576
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0964 0.1037
Brugia malayi SWIRM domain containing protein 0.059 0.3161 1
Onchocerca volvulus 0.0032 0.0126 0.0396
Echinococcus granulosus microtubule associated protein 2 0.068 0.3648 0.3924
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0213 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.004 0.0223
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0077 0.0243
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0011 0.0012
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0032 0.0126 0.0126
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0199 0.2309
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0036 0.0172
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0355 0.0382
Toxoplasma gondii histone lysine-specific demethylase 0.0124 0.0626 0.6088
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0025 0.0085 0.0085
Loa Loa (eye worm) G protein alpha subunit 3 0.0025 0.0085 0.0092
Schistosoma mansoni microtubule-associated protein tau 0.068 0.3648 0.3924
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0036 0.0336
Schistosoma mansoni hypothetical protein 0.1719 0.9297 1
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0124 0.0626 0.7552
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0011 0.0009 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.1023 0.5542
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0025 0.0085 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0057 0.0062
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0186 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.0026 0.0094 0.0101
Treponema pallidum NADH oxidase 0.0016 0.0036 0.0336
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0253 0.1538
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0057 0.0062
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0025 0.0085 0.027
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0302 0.2142
Schistosoma mansoni nocturnin 0.0032 0.0126 0.0135
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0123
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0006 0.0007
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0011 0.0009 0.001
Schistosoma mansoni cpg binding protein 0.0058 0.0264 0.0284
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0579 0.3101 0.3336
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0036
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0131 0.066 0.4718
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0011 0.0015
Echinococcus multilocularis dna polymerase kappa 0.0076 0.0365 0.0365
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0518 0.3719
Onchocerca volvulus Glucosylceramidase homolog 0.0174 0.0894 0.2827
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0036 0.0039
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0338 0.0364
Schistosoma mansoni thyroid hormone receptor 0.002 0.0057 0.0062
Brugia malayi tailless protein 0.0009 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0077 0.0371
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0057 0.0062
Echinococcus granulosus chromobox protein 1 0.0069 0.0323 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Toxoplasma gondii thioredoxin reductase 0.0046 0.0199 0.1875
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0126 0.1408
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.2142 0.2142
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0011 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0253 0.177
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0057 0.0062
Echinococcus multilocularis cpg binding protein 0.0061 0.0282 0.0282
Onchocerca volvulus Huntingtin homolog 0.0121 0.0607 0.1918
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Schistosoma mansoni kinase 0.0095 0.0467 0.0502
Brugia malayi kap beta 3 protein 0.003 0.0116 0.0366
Brugia malayi TAR-binding protein 0.0075 0.0355 0.1125
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0077 0.0371
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0155 0.177
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0684 0.0736
Brugia malayi Importin beta-1 subunit 0.0161 0.0826 0.2612
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0048
Plasmodium falciparum glutathione reductase 0.0016 0.0036 0.031
Echinococcus multilocularis importin subunit beta 1 0.0161 0.0826 0.0826
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0187
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0253 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0057 0.0181
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0048
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0001 0.0001
Toxoplasma gondii SWIRM domain-containing protein 0.0045 0.0193 0.1817
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0011 0.0009 0.0009
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0025 0.0085 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0077 0.0495
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0116 0.0125
Brugia malayi SWIRM domain containing protein 0.0045 0.0193 0.0611
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.004 0.0223
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0174 0.0187
Plasmodium falciparum DNase I-like protein, putative 0.0032 0.0126 0.1408
Loa Loa (eye worm) hypothetical protein 0.0044 0.0187 0.0201
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0036 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Schistosoma mansoni carbon catabolite repressor protein 0.0032 0.0126 0.0135
Leishmania major DNA polymerase eta, putative 0.0024 0.0079 0.044
Brugia malayi hypothetical protein 0.0009 0.0001 0.0002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0036 0.0172
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0076 0.0365 0.0393
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0033 0.0033
Entamoeba histolytica hypothetical protein 0.0011 0.0011 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0082 0.0531
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0303 0.1597 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0032 0.0126 0.0735
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0011 0.0009 0.001
Schistosoma mansoni ran 0.0093 0.0459 0.0493
Leishmania major DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Leishmania major hypothetical protein, conserved 0.0032 0.0126 0.0735
Giardia lamblia Inositol 5-phosphatase 4 0.0032 0.0126 0.1223
Leishmania major DNA damage repair protein, putative 0.0024 0.0079 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0193 0.1335
Echinococcus granulosus chromobox protein 2 0.0011 0.0011 0.0012
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0124 0.0626 0.0674
Loa Loa (eye worm) hypothetical protein 0.0057 0.026 0.028
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0036 0.031
Onchocerca volvulus 0.0046 0.0201 0.0633
Trypanosoma brucei DNA polymerase IV, putative 0.0076 0.0365 0.2243
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0006 0.0007
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0174 0.1196
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0036 0.0039
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0032 0.0126 0.0846
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0235 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Echinococcus multilocularis translational activator gcn1 0.003 0.0116 0.0116
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0077 0.0243
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0024 0.0079 0.0689
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0036 0.0286
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0007 0.0021
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0025 0.0085 0.027
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0006 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0729 0.4537
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0057 0.0062
Onchocerca volvulus 0.0057 0.026 0.0822
Entamoeba histolytica hypothetical protein 0.0011 0.0011 0.0022
Plasmodium vivax importin-beta 2, putative 0.0161 0.0826 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0011 0.0011
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0174 0.0174
Schistosoma mansoni cpg binding protein 0.0061 0.0282 0.0303
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0253 0.1538
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0253 0.2558
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0009 0.0001 0.0001
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0235 0.0744
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0011 0.0035
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0235 0.0235
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0236 0.1431
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0075 0.0355 0.0382
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0011 0.0022
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.026 0.028
Mycobacterium ulcerans FAD-linked oxidoreductase 0.0028 0.0101 0.05
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0009 0.001
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0518 0.3719
Brugia malayi Thioredoxin reductase 0.0046 0.0199 0.063
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0085
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0161 0.0956
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0101 0.1098
Trypanosoma cruzi polo-like protein kinase, putative 0.0186 0.0964 0.6012
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0036 0.0269
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0044 0.0187 0.1289
Loa Loa (eye worm) TAR-binding protein 0.0075 0.0355 0.0382
Loa Loa (eye worm) acetyltransferase 0.014 0.0712 0.0765
Schistosoma mansoni aldehyde dehydrogenase 0.0197 0.1023 0.11
Loa Loa (eye worm) glutathione reductase 0.0046 0.0199 0.0214
Trypanosoma brucei importin beta-1 subunit, putative 0.0161 0.0826 0.5142
Echinococcus granulosus lamin dm0 0.0057 0.026 0.028
Echinococcus multilocularis Chromo domain 0.0011 0.0011 0.0011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0161 0.0956
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0323 0.0348
Trypanosoma cruzi DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0161 0.0161
Echinococcus multilocularis deoxyribonuclease 1 2 0.0032 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0025 0.0085 0.0092
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0201 0.0201
Trypanosoma brucei polo-like protein kinase 0.0186 0.0964 0.6012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0116 0.0125
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.01 0.0107
Schistosoma mansoni chromobox protein 0.0069 0.0323 0.0348
Brugia malayi nuclear receptor NHR-88 0.002 0.0057 0.0181
Schistosoma mansoni amine oxidase 0.0124 0.0626 0.0674
Brugia malayi G-protein alpha subunit 0.0025 0.0085 0.027
Echinococcus granulosus importin 5 0.003 0.0116 0.0124
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0126 0.0135
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0057 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0579 0.3101 0.3336
Leishmania major hypothetical protein, conserved 0.003 0.0116 0.0671
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0253 0.2409
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0161 0.11
Loa Loa (eye worm) hypothetical protein 0.0161 0.0826 0.0888
Trypanosoma cruzi UDP-galactopyranose mutase 0.0124 0.0626 0.3886
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0253 0.1538
Schistosoma mansoni GTP-binding protein alpha subunit 0.0025 0.0085 0.0092
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0174 0.1202
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0161 0.0173
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.016 0.0821 0.0883
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0197 0.1023 0.11
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0323 0.2279
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0174 0.1999
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Toxoplasma gondii hypothetical protein 0.0049 0.0216 0.2038
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0079 0.044
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Echinococcus granulosus survival motor neuron protein 1 0.0508 0.2711 0.2916
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Onchocerca volvulus 0.0042 0.0177 0.056
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0093 0.0459 0.4434
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0011 0.0035
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0064 0.0204
Trypanosoma brucei PAB1-binding protein , putative 0.0108 0.0539 0.334
Mycobacterium ulcerans dehydrogenase 0.0124 0.0626 0.3374
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0011 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0355 0.0382
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0032 0.0126 0.0735
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0006 0.0007
Onchocerca volvulus 0.0058 0.0264 0.0833
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0032 0.0126 0.0735
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0057 0.0062
Loa Loa (eye worm) hypothetical protein 0.004 0.0168 0.0181
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0579 0.3101 0.3101
Mycobacterium ulcerans lipase LipD 0.0041 0.0174 0.0899
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.0101 0.0668
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0025 0.0085 0.0092
Brugia malayi glutathione reductase 0.0046 0.0199 0.063
Trichomonas vaginalis inositol monophosphatase, putative 0.0072 0.0344 0.2426
Mycobacterium tuberculosis Probable reductase 0.0104 0.0518 0.3719
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0077 0.0371
Onchocerca volvulus 0.0032 0.0126 0.0396
Plasmodium vivax ataxin-2 like protein, putative 0.0108 0.0539 0.6486
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0083
Echinococcus granulosus geminin 0.0169 0.0867 0.0933
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0036 0.0172
Loa Loa (eye worm) nuclear hormone receptor 0.0009 0.0001 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0077 0.071
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0036 0.031
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0032 0.0126 0.1223
Entamoeba histolytica rodhanase-like domain containing protein 0.0044 0.0187 0.1862
Loa Loa (eye worm) hypothetical protein 0.0178 0.0917 0.0987
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.004 0.0043
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0036 0.0336
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0025 0.0085 0.0085
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0011 0.0009 0.0029
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0187
Onchocerca volvulus 0.0234 0.1223 0.3867
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0253 0.1538
Mycobacterium ulcerans hypothetical protein 0.0024 0.0079 0.0382
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0057 0.0062
Trichomonas vaginalis DNA polymerase eta, putative 0.0076 0.0365 0.2582
Brugia malayi nuclear receptor RXR 0.001 0.0007 0.0021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.01 0.01
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0032 0.0126 0.0735
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0093 0.0459 0.2831
Plasmodium vivax transportin, putative 0.003 0.0116 0.1283
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0264 0.1389 0.1494
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Mycobacterium ulcerans FAD-dependent oxidoreductase 0.0028 0.0101 0.05
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0338 0.0338
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0124 0.0626 0.7552
Brugia malayi chromobox protein homolog 3 0.0038 0.0159 0.0504
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0077 0.071
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0174 0.0187
Echinococcus granulosus ubiquinone biosynthesis monooxygenase COQ6 0.0028 0.0101 0.0108
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0126 0.1408
Brugia malayi exodeoxyribonuclease III family protein 0.016 0.0821 0.2596
Onchocerca volvulus 0.0011 0.0011 0.0033
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0178 0.0917 0.2901
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0582 0.9279
Plasmodium falciparum transportin 0.003 0.0116 0.1283
Brugia malayi nuclear hormone receptor 0.002 0.0057 0.0181
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0057 0.0181
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0026 0.0171
Entamoeba histolytica serine/threonine protein kinase, putative 0.0186 0.0964 1
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0052 0.0164
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0057 0.0062
Schistosoma mansoni hypothetical protein 0.0403 0.2142 0.2304
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0116 0.0116
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0347 0.1838 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0282 0.0303
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0045 0.0195
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.0007 0.0007
Onchocerca volvulus 0.059 0.3161 1
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0032 0.0126 0.1223
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0253 0.177
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0057 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0116 0.0125
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0077 0.1098
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0092
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Schistosoma mansoni nuclear receptor 0.0009 0.0001 0.0001
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0076 0.0365 0.0393
Mycobacterium tuberculosis Conserved hypothetical protein 0.0124 0.0626 0.4507
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0032 0.0126 0.0135
Schistosoma mansoni DNA polymerase IV / kappa 0.0024 0.0079 0.0085
Entamoeba histolytica rodhanase-like domain containing protein 0.0044 0.0187 0.1862
Echinococcus multilocularis snurportin 1 0.1719 0.9297 0.9297
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0201 0.0216
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.0101 0.0668
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0032 0.0126 0.0846
Giardia lamblia DINP protein human, muc B family 0.0076 0.0365 0.3731
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0174 0.0899
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0174 0.1036
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0093 0.0459 0.5494
Schistosoma mansoni zinc finger protein 0.0009 0.0001 0.0001
Brugia malayi beta-lactamase family protein 0.0041 0.0174 0.0549
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0155 0.1532
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0076 0.0365 0.2601
Onchocerca volvulus 0.0023 0.0077 0.0241
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0057 0.0179
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0159 0.0502
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0235 0.0253
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0126 0.1223
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0032 0.0126 0.1408
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Echinococcus multilocularis 0.0124 0.0626 0.0626
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0626 0.7552
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0236 0.1431
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0174 0.2666
Loa Loa (eye worm) importin-beta domain-containing protein 0.003 0.0116 0.0124
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0253 0.0272
Schistosoma mansoni SWI/SNF complex-related 0.0045 0.0193 0.0208
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.016 0.0821 0.5111
Echinococcus granulosus dna polymerase kappa 0.0076 0.0365 0.0393
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0006 0.0007
Schistosoma mansoni amine oxidase 0.0124 0.0626 0.0674
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0729 0.4537
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Entamoeba histolytica G protein alpha subunit, putative 0.0025 0.0085 0.0799
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0011 0.0035
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Brugia malayi hypothetical protein 0.0009 0.0001 0.0002
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0235 0.0253
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0093 0.0459 0.4708
Loa Loa (eye worm) hypothetical protein 0.0044 0.0187 0.0201
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0579 0.3101 0.3101
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0011 0.0009 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.0684 0.0736
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1223
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0011 0.0015
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0076 0.0365 0.2601
Echinococcus granulosus inositol monophosphatase 1 0.0072 0.0344 0.037
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0582 0.4182
Trypanosoma brucei importin beta-1 subunit, putative 0.0161 0.0826 0.5142
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0048
Echinococcus granulosus thyroid hormone receptor alpha 0.0009 0.0001 0.0001
Trypanosoma brucei chrX additional, unordered contigs 0.0024 0.0079 0.044
Echinococcus granulosus lysine specific histone demethylase 1A 0.0546 0.2917 0.3138
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0355 0.0382
Trichomonas vaginalis cdc25c, putative 0.0044 0.0187 0.1289
Brugia malayi polk-prov protein 0.0024 0.0079 0.0249
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0303 0.1597 1
Echinococcus multilocularis protein MICAL 3 0.0028 0.0101 0.0101
Brugia malayi orphan nuclear receptor NR2E1 0.0009 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0057 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0057 0.0181
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0032 0.0126 0.1223
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0174 0.1202
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0116 0.1059
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0036 0.0149
Loa Loa (eye worm) hypothetical protein 0.0298 0.157 0.1688
Plasmodium falciparum ataxin-2 like protein, putative 0.0108 0.0539 0.6486
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Brugia malayi CXXC zinc finger family protein 0.0058 0.0264 0.0835
Schistosoma mansoni elf1 0.001 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0036 0.0198
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0124 0.0626 0.3374
Plasmodium falciparum protoporphyrinogen oxidase 0.0124 0.0626 0.7552
Toxoplasma gondii LsmAD domain-containing protein 0.0108 0.0539 0.5232
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0011 0.0015
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0032 0.0126 0.0846
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Brugia malayi Ets-domain containing protein 0.0071 0.0338 0.107
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0025 0.0085 0.027
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0126 0.0135
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0161 0.0173
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0012
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0006 0.0007
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0214 0.1113 0.1113
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0174 0.1202
Mycobacterium ulcerans oxidoreductase 0.0028 0.0101 0.05
Brugia malayi nuclear receptor RXR 0.0009 0.0001 0.0002
Brugia malayi CCR4 0.0032 0.0126 0.0398
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Loa Loa (eye worm) RNA binding protein 0.0075 0.0355 0.0382
Brugia malayi MAP kinase sur-1 0.0056 0.0253 0.0801
Brugia malayi mbt repeat family protein 0.0046 0.0201 0.0635
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0025 0.0085 0.0092
Treponema pallidum hypothetical protein 0.0032 0.0126 0.1438
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0093 0.0459 0.5494
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0036 0.0036
Onchocerca volvulus 0.0044 0.0187 0.0589
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0124 0.0626 0.7552
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1223
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.004 0.0168 0.0181
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0011 0.00000000023901
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Toxoplasma gondii HEAT repeat-containing protein 0.0161 0.0826 0.8054
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.016 0.0821 0.5111
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0199 0.1388
Trichomonas vaginalis cdc25b, putative 0.0044 0.0187 0.1289
Brugia malayi beta-lactamase family protein 0.0041 0.0174 0.0549
Schistosoma mansoni nuclear receptor nhr-48 0.0009 0.0001 0.0001
Schistosoma mansoni terminal deoxycytidyl transferase 0.0076 0.0365 0.0393
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0011 0.0021
Brugia malayi hypothetical protein 0.001 0.0007 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0077 0.0371
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0082 0.0531
Loa Loa (eye worm) nuclear receptor NHR-67 0.0009 0.0001 0.0001
Brugia malayi Ets-domain containing protein 0.001 0.0006 0.002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0053 0.0053
Echinococcus multilocularis protein C ets 2 0.001 0.0006 0.0006
Trypanosoma cruzi importin beta-1 subunit, putative 0.0131 0.066 0.4099
Plasmodium falciparum DNA repair protein REV1, putative 0.0024 0.0079 0.0832
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0199 0.0199
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0116 0.1051
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0187
Echinococcus granulosus transportin 1 0.003 0.0116 0.0124
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0126 0.1223
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0057 0.0057
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.016 0.0821 0.4437
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0079 0.044
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0253 0.1538
Schistosoma mansoni ets-related 0.0217 0.1128 0.1214
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0036
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0187
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0025 0.0085 0.0553
Plasmodium falciparum ataxin-2 like protein, putative 0.0108 0.0539 0.6486
Leishmania major UDP-galactopyranose mutase 0.0124 0.0626 0.3886
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0025 0.0085 0.0092
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0197 0.1023 0.1023
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0266 0.1397 0.1503
Echinococcus multilocularis protoporphyrinogen oxidase 0.0124 0.0626 0.0626
Schistosoma mansoni hypothetical protein 0.0312 0.1649 0.1774
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0579 0.3101 0.3336
Trypanosoma cruzi mitochondrial protein 99, putative 0.0032 0.0126 0.0735
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0622 0.0669
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0006 0.0006
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0546 0.2917 0.3138
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0033 0.0131 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0057 0.0062
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0712 0.2251
Echinococcus granulosus FTZ F1 alpha 0.002 0.0057 0.0062
Echinococcus granulosus GTP binding nuclear protein Ran 0.0093 0.0459 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0057 0.0181
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1223
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0025 0.0085 0.0085
Echinococcus granulosus bloom syndrome protein 0.0021 0.0064 0.0069
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0032 0.0126 0.0735
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.0101 0.0668
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0009 0.001
Loa Loa (eye worm) RecQ helicase 0.0021 0.0064 0.0069
Onchocerca volvulus 0.002 0.0057 0.0179
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0079 0.0689
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0025 0.0085 0.027
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0057 0.0181
Trichomonas vaginalis hypothetical protein 0.003 0.0116 0.0772
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0049 0.0292
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0302 0.4754
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0079 0.044
Loa Loa (eye worm) inositol-1 0.0072 0.0344 0.037
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0104 0.0111
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0076 0.0365 0.2582
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0077 0.0495
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0025 0.0085 0.0553
Brugia malayi RNA binding protein 0.0075 0.0355 0.1125
Loa Loa (eye worm) hypothetical protein 0.0076 0.0365 0.0393
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0082 0.0531
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0175 0.1205
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0082 0.0531
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0057 0.0181
Giardia lamblia Kinase, PLK 0.0186 0.0964 1
Loa Loa (eye worm) hypothetical protein 0.0546 0.2917 0.3138
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0025 0.0085 0.0092
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0032 0.0126 0.1408
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0182 0.1087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.004 0.0223
Echinococcus granulosus tar DNA binding protein 0.0075 0.0355 0.0382
Giardia lamblia hypothetical protein 0.0032 0.0126 0.1223
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Mycobacterium ulcerans oxidoreductase GMC-type 0.0028 0.0101 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0159 0.1089
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Trichomonas vaginalis ran, putative 0.0093 0.0459 0.3258
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0036 0.0172
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0034 0.0034
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0032 0.0126 0.0735
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0009 0.0001 0.0001
Trichomonas vaginalis helicase, putative 0.0013 0.0021 0.0088
Echinococcus multilocularis transportin 1 0.003 0.0116 0.0116
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0579 0.3101 0.9811
Schistosoma mansoni importin-beta 2 0.003 0.0116 0.0124
Brugia malayi hypothetical protein 0.001 0.0007 0.0021
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0072 0.0344 0.4123
Mycobacterium leprae Probable lipase LipE 0.0041 0.0174 0.2666
Brugia malayi Pre-SET motif family protein 0.0206 0.1069 0.3382
Trypanosoma brucei kynurenine 3-monooxygenase, putative 0.0028 0.0101 0.0576
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0082 0.0531
Schistosoma mansoni GTP-binding protein alpha subunit 0.0025 0.0085 0.0092
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.016 0.0821 0.0883
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0174 0.1193
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0213 0.0675
Loa Loa (eye worm) aldehyde dehydrogenase 0.0011 0.0009 0.001
Brugia malayi RNA, U transporter 1 0.0458 0.244 0.7719
Toxoplasma gondii FAD binding domain-containing protein 0.0028 0.0101 0.0903
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Echinococcus multilocularis ubiquinone biosynthesis monooxygenase COQ6 0.0028 0.0101 0.0101
Toxoplasma gondii FAD binding domain-containing protein 0.0028 0.0101 0.0903
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0029 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0057 0.0062
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0161 0.0509
Leishmania major hypothetical protein, conserved 0.0032 0.0126 0.0735
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0057 0.0181
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.013 0.0412
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0546 0.2917 0.2917
Schistosoma mansoni neutral sphingomyelinase 0.0032 0.0126 0.0135
Loa Loa (eye worm) hypothetical protein 0.0032 0.0126 0.0135
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0093 0.0459 0.0493
Leishmania major importin beta-1 subunit, putative 0.0131 0.066 0.4099
Echinococcus multilocularis GPCR, family 2 0.0015 0.0033 0.0033
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0036 0.0199
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0093 0.0459 0.2831
Loa Loa (eye worm) hypothetical protein 0.0169 0.0869 0.0935
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0126 0.1408
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Brugia malayi nuclear hormone receptor 0.0009 0.0001 0.0002
Brugia malayi intermediate filament protein 0.0057 0.026 0.0824
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0174 0.1627
Loa Loa (eye worm) hypothetical protein 0.0045 0.0193 0.0208
Trichomonas vaginalis hypothetical protein 0.0011 0.0011 0.0015
Schistosoma mansoni cpg binding protein 0.0061 0.0282 0.0303
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0033 0.0106
Chlamydia trachomatis monooxygenase 0.0028 0.0101 0.1088
Brugia malayi CHD4 protein 0.0015 0.0029 0.0092
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0077 0.0371
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0025 0.0085 0.0092
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0025 0.0085 0.0092
Echinococcus granulosus GPCR family 2 0.0015 0.0033 0.0036
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0009 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0011 0.0009 0.001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0076 0.0365 0.0393
Brugia malayi hypothetical protein 0.0108 0.0539 0.1706
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0033 0.0036
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0011 0.0012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0175 0.0553
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0116 0.0125
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.0365 0.2243
Leishmania major trypanothione reductase 0.0046 0.0199 0.1197
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0569 0.5526
Echinococcus granulosus snurportin 1 0.1719 0.9297 1
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0201 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Brugia malayi nuclear receptor NHR-67 0.0009 0.0001 0.0002
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0011 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0056 0.0255 0.0274
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0011 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0034 0.0034
Plasmodium vivax exodeoxyribonuclease III, putative 0.0032 0.0126 0.1408
Toxoplasma gondii exonuclease III APE 0.016 0.0821 0.8006
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0161 0.159
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.016 0.0821 0.5111
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0057 0.0181
Echinococcus granulosus nuclear receptor nhr 48 0.0009 0.0001 0.0001
Brugia malayi aldehyde dehydrogenase 0.0011 0.0009 0.0029
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0064 0.0401
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0053 0.0057
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0214 0.1113 0.1198
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Giardia lamblia DNA damage repair protein 0.0024 0.0079 0.0732
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0011 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0161 0.11
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0011 0.0009 0.0029
Schistosoma mansoni gabp alpha 0.0071 0.0338 0.0364
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0057 0.0062
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0025 0.0085 0.0092
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0174 0.0549
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0079 0.044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.0344 0.2426
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0057 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0174 0.1036
Brugia malayi N-terminal motif family protein 0.0178 0.0917 0.2903
Plasmodium vivax FAD-dependent monooxygenase, putative 0.0028 0.0101 0.1098
Onchocerca volvulus 0.0025 0.0085 0.0268
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0032 0.0126 0.0846
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0033 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0355 0.0382
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0201 0.0633
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0025 0.0085 0.0092
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0025 0.0085 0.0085
Trichomonas vaginalis set domain proteins, putative 0.0234 0.1223 0.8797
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0453 0.322
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0006 0.0007
Entamoeba histolytica SWIRM domain protein 0.0045 0.0193 0.193
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0009 0.0001 0.0001
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0025 0.0085 0.0092
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.016 0.0821 0.0821
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0253 0.1538
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0029 0.0029
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0347 0.1838 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0083
Loa Loa (eye worm) hypothetical protein 0.0508 0.2711 0.2916
Echinococcus multilocularis tar DNA binding protein 0.0075 0.0355 0.0355
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0582 0.4182
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0098 0.0646
Plasmodium falciparum thioredoxin reductase 0.0046 0.0199 0.2309
Trypanosoma cruzi DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0025 0.0085 0.0553
Brugia malayi Nuclear hormone receptor E75 0.0009 0.0001 0.0002
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0032 0.0126 0.0846
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0344 0.2107
Echinococcus granulosus importin subunit beta 1 0.0161 0.0826 0.0888
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Brugia malayi follicle stimulating hormone receptor 0.0266 0.1397 0.4421
Giardia lamblia hypothetical protein 0.0045 0.0193 0.193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0082 0.0531
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0011 0.0009 0.001
Toxoplasma gondii ABC1 family protein 0.0041 0.0174 0.1623
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0006 0.0007
Brugia malayi Protein cec-1. 0.0011 0.0011 0.0035
Mycobacterium tuberculosis Conserved protein 0.0041 0.0174 0.1202
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0057 0.0062
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0108
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0712 0.0765
Schistosoma mansoni hypothetical protein 0.0049 0.0214 0.0231
Loa Loa (eye worm) hypothetical protein 0.0108 0.0539 0.058
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1389 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0006 0.002
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0201 0.0216
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0174 0.1627
Echinococcus granulosus cpg binding protein 0.0061 0.0282 0.0303
Echinococcus multilocularis chromobox protein 1 0.0069 0.0323 0.0323
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0001 0.0001
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0045 0.0193 0.0208
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.016 0.0817 0.442
Echinococcus multilocularis ets variant gene 4 0.001 0.0006 0.0006
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.003 0.0116 0.0671
Loa Loa (eye worm) hypothetical protein 0.0052 0.0235 0.0253
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0355 0.0382
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0036 0.0172
Wolbachia endosymbiont of Brugia malayi 2-polyprenyl-6-methoxyphenol 4-hydroxylase 0.0028 0.0101 0.1127
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0174 0.1193
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0036 0.0269
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Mycobacterium ulcerans hypothetical protein 0.0028 0.0101 0.05
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0077 0.0427
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0161 0.11
Echinococcus granulosus neutral sphingomyelinase 0.0032 0.0126 0.0135
Schistosoma mansoni lamin 0.0057 0.026 0.028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0174 0.1196
Loa Loa (eye worm) hypothetical protein 0.0046 0.0201 0.0216
Trypanosoma cruzi DNA polymerase eta, putative 0.0024 0.0079 0.044
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0025 0.0085 0.027
Loa Loa (eye worm) hypothetical protein 0.0032 0.0126 0.0135
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0213 0.0675
Loa Loa (eye worm) hypothetical protein 0.0124 0.0626 0.0674
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0182 0.1087
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0025 0.0085 0.0092
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0161 0.0956
Schistosoma mansoni hypothetical protein 0.0169 0.0867 0.0933
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Trichomonas vaginalis esterase, putative 0.0041 0.0174 0.1193
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0253 0.0272
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0036
Leishmania major endonuclease/exonuclease protein-like protein 0.0032 0.0126 0.0735
Loa Loa (eye worm) hypothetical protein 0.059 0.3161 0.34
Mycobacterium ulcerans beta-lactamase 0.0041 0.0174 0.0899
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0303 0.1597 1
Schistosoma mansoni hypothetical protein 0.0169 0.0867 0.0933
Trichomonas vaginalis Phospholipase C precursor, putative 0.0032 0.0126 0.0846
Plasmodium vivax glutathione reductase, putative 0.0046 0.0199 0.2309
Mycobacterium leprae possibleputative FAD-linked oxidoreductase 0.0028 0.0101 0.1483
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0253 0.177
Trypanosoma cruzi Monooxygenase, putative 0.0028 0.0101 0.0576
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0116 0.0368
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0025 0.0085 0.0553
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.016 0.0821 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.0101 0.0668
Schistosoma mansoni inositol monophosphatase 0.0072 0.0344 0.037
Echinococcus multilocularis geminin 0.0169 0.0867 0.0867
Loa Loa (eye worm) hypothetical protein 0.0026 0.0094 0.0101
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0161 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0579 0.3101 0.3336
Brugia malayi ecdysteroid receptor 0.002 0.0057 0.0181
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0077 0.0243
Brugia malayi steroid hormone receptor 0.002 0.0057 0.0181
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0006 0.0006
Brugia malayi Nuclear hormone receptor E75 0.0009 0.0001 0.0002
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0124 0.0626 1
Brugia malayi Fli-1 protein 0.0217 0.1128 0.357
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0044 0.0187 0.1289
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0092
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0036 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0044 0.0187 0.0201
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0025 0.0085 0.0553
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.1069 0.115
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0253 0.0272
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0161 0.0161
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0199 0.0214
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0006 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0082 0.0531
Brugia malayi hypothetical protein 0.0025 0.0085 0.027
Schistosoma mansoni aldehyde dehydrogenase 0.0197 0.1023 0.11
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0174 0.1202
Plasmodium falciparum thioredoxin reductase 0.0016 0.0036 0.031
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0079 0.044
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0161 0.159
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0006 0.0007
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0093 0.0459 0.0459
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0057 0.0181
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0025 0.0085 0.027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0174 0.1995
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0025 0.0085 0.0553
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0053 0.0057
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0253 0.0272
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0036 0.0172
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0009 0.001
Entamoeba histolytica SWIRM domain protein 0.0045 0.0193 0.193
Brugia malayi hypothetical protein 0.0121 0.0607 0.1919
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0011 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0057 0.0057
Brugia malayi Rhodanese-like domain containing protein 0.0044 0.0187 0.0591
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Loa Loa (eye worm) helicase 0.0011 0.0011 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0174 0.1193
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0079 0.0689
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0453 0.322
Mycobacterium tuberculosis Probable exported protein 0.0032 0.0126 0.0852
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0187
Onchocerca volvulus 0.0044 0.0187 0.0589
Onchocerca volvulus 0.0041 0.0174 0.0547
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0009 0.0001 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.0001 0.0001
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0032 0.0126 0.0135
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0177 0.0191
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0034 0.0036
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0201 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Brugia malayi RNA recognition motif domain containing protein 0.0075 0.0355 0.1125
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0518 0.3719
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0161 0.0173
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1389 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0344 0.2107
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0032 0.0126 0.0846
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0032 0.0126 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0116 0.0125
Trichomonas vaginalis ap endonuclease, putative 0.016 0.0821 0.5883
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0011 0.0035
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0072 0.0344 0.1829
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0182 0.1087
Brugia malayi conserved hypotetical protein 0.0009 0.0001 0.0002
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0057 0.0057
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0174 0.0187
Trypanosoma brucei unspecified product 0.0053 0.0236 0.1431
Mycobacterium ulcerans oxidoreductase 0.0124 0.0626 0.3374
Onchocerca volvulus 0.0041 0.0174 0.0547
Echinococcus granulosus expressed protein 0.0025 0.0085 0.0092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0187
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0116 0.0125
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0033 0.0036
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Echinococcus multilocularis nuclear receptor nhr 48 0.0009 0.0001 0.0001
Schistosoma mansoni importin beta-1 0.0161 0.0826 0.0888
Onchocerca volvulus 0.0057 0.026 0.0822
Onchocerca volvulus 0.0011 0.0011 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1389 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0057 0.0181
Echinococcus granulosus synaptojanin 1 0.0032 0.0126 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Brugia malayi hypothetical protein 0.0124 0.0626 0.1981
Echinococcus granulosus protein C ets 2 0.001 0.0006 0.0007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0057 0.0062
Schistosoma mansoni ap endonuclease 0.016 0.0821 0.0883
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0131 0.066 0.4718
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0027 0.0199
Onchocerca volvulus 0.0041 0.0174 0.0547
Mycobacterium ulcerans hypothetical protein 0.0028 0.0101 0.05
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.1023 0.5542
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0201 0.0216
Leishmania major RNA-editing complex protein MP100, putative 0.0032 0.0126 0.0735
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0161 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0057 0.0181
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0032 0.0126 0.0735
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0518 0.3719
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0064 0.0064
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0011 0.0022
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0077 0.0427
Entamoeba histolytica deoxycytidyl transferase, putative 0.0076 0.0365 0.3731
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0712 0.0712
Chlamydia trachomatis protoporphyrinogen oxidase 0.0124 0.0626 1
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0945 0.6783
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0077 0.071
Mycobacterium ulcerans hypothetical protein 0.0041 0.0174 0.0899
Schistosoma mansoni thyroid hormone receptor 0.002 0.0057 0.0062
Loa Loa (eye worm) beta-lactamase 0.0041 0.0174 0.0187
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0079 0.044
Mycobacterium ulcerans oxidoreductase 0.0028 0.0101 0.05
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0044 0.0187 0.1289
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0253 0.0253
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Onchocerca volvulus Putative neutral sphingomyelinase 0.0032 0.0126 0.0396
Entamoeba histolytica rodhanase-like domain containing protein 0.0044 0.0187 0.1862
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0009 0.001
Trypanosoma brucei RNA editing exonuclease 2 0.0032 0.0126 0.0735
Leishmania major mitochondrial DNA polymerase beta 0.0303 0.1597 1
Brugia malayi nuclear receptor NHR-88 0.0009 0.0001 0.0002
Schistosoma mansoni nuclear receptor 0.0009 0.0001 0.0001
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0045 0.0413
Echinococcus multilocularis chromobox protein 2 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0048
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0077 0.0371
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0518 0.8252
Echinococcus granulosus lysine specific histone demethylase 1A 0.0124 0.0626 0.0674
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0033 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0253 0.177
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0011 0.0015
Trypanosoma cruzi mitochondrial protein 99, putative 0.0032 0.0126 0.0735
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0264 0.1389 0.4393
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0057 0.0062
Echinococcus granulosus translational activator gcn1 0.003 0.0116 0.0124
Plasmodium vivax SET domain protein, putative 0.0031 0.0116 0.1292
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0155 0.1532
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0057 0.0062
Onchocerca volvulus 0.0104 0.0513 0.1622
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0057 0.0062
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0201 0.0201
Echinococcus granulosus traf and tnf receptor associated protein 0.0032 0.0126 0.0135
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0057 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0079 0.044
Leishmania major GTP-binding protein, putative 0.0093 0.0459 0.2831
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0093 0.0459 0.1451
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0197 0.1023 0.6384
Echinococcus granulosus dna polymerase eta 0.0076 0.0365 0.0393
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0057 0.0057
Brugia malayi transcription factor E74 isoform 0.001 0.0006 0.002
Echinococcus multilocularis expressed protein 0.0025 0.0085 0.0085
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.016 0.0821 0.5927
Trypanosoma brucei trypanothione reductase 0.0046 0.0199 0.1197
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.0365 0.1155
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0064 0.0401
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0025 0.0085 0.0092
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0518 0.3719
Mycobacterium tuberculosis Conserved protein 0.0041 0.0174 0.1202
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0079 0.044
Echinococcus granulosus chromobox protein 1 0.0069 0.0323 0.0348
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0079 0.044
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0174 0.0899
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0029 0.0031
Brugia malayi hypothetical protein 0.0298 0.157 0.4966
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.0101 0.0668
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0032 0.0126 0.0135
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0057 0.0062
Schistosoma mansoni ran 0.0093 0.0459 0.0493
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0057 0.0062
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1389 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0011 0.00000000023901
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0126 0.0135
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0036 0.031
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Mycobacterium ulcerans hypothetical protein 0.0028 0.0101 0.05
Brugia malayi hypothetical protein 0.007 0.033 0.1046
Schistosoma mansoni chromobox protein 0.0011 0.0011 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0057 0.0181
Trichomonas vaginalis ap endonuclease, putative 0.016 0.0821 0.5883
Echinococcus granulosus Chromo domain 0.0011 0.0011 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Brugia malayi Rhodanese-like domain containing protein 0.0044 0.0187 0.0591
Brugia malayi MH2 domain containing protein 0.0135 0.0684 0.2164
Leishmania major hypothetical protein, conserved 0.0041 0.0174 0.1036
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0186 0.0964 0.1037
Schistosoma mansoni intermediate filament proteins 0.0057 0.026 0.028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.004 0.0223
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0036 0.031
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0032 0.0126 0.0846
Trypanosoma brucei protein kinase, putative 0.0056 0.0253 0.1538
Mycobacterium ulcerans membrane-associated oxidoreductase 0.0028 0.0101 0.05
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0582 0.4182
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0032 0.0126 0.0735
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.0817 0.5904
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0186 0.0964 0.6012
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0201 0.0216
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0032 0.0126 0.0135
Schistosoma mansoni hypothetical protein 0.0104 0.0513 0.0552
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0044 0.0187 0.1289
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0116 0.1051
Schistosoma mansoni chromobox protein 0.0069 0.0323 0.0348
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0057 0.0062
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0072 0.0344 0.3505
Brugia malayi hypothetical protein 0.0508 0.2711 0.8576
Plasmodium vivax DNA repair protein REV1, putative 0.0024 0.0079 0.0832
Loa Loa (eye worm) hypothetical protein 0.0028 0.01 0.0107
Echinococcus multilocularis inositol monophosphatase 1 0.0072 0.0344 0.0344
Echinococcus granulosus lamin 0.0057 0.026 0.028
Schistosoma mansoni ets-related 0.001 0.0006 0.0007
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0045 0.0261
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0338 0.0364
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0344 0.2107
Echinococcus multilocularis microtubule associated protein 2 0.068 0.3648 0.3648
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0048
Echinococcus multilocularis chromobox protein 1 0.0069 0.0323 0.0323
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0323 0.2279
Onchocerca volvulus 0.0044 0.0187 0.0589
Schistosoma mansoni ap endonuclease 0.016 0.0821 0.0883
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0223 0.1162 0.8421
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0011 0.0021
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0032 0.0122 0.0709
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0076 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Entamoeba histolytica hypothetical protein 0.0011 0.0011 0.0022
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0344 0.2107
Loa Loa (eye worm) hypothetical protein 0.0121 0.0607 0.0652
Brugia malayi nuclear hormone receptor family member odr-7 0.0009 0.0001 0.0002
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1223
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0174 0.0187
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0077 0.1098
Loa Loa (eye worm) hypothetical protein 0.0546 0.2917 0.3138
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0025 0.0085 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0057 0.0062
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.016 0.0821 0.994
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Schistosoma mansoni hypothetical protein 0.0033 0.013 0.014
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0011 0.0009 0.001
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0025 0.0085 0.027
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0104 0.0513 0.1623
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Leishmania major DNA polymerase eta, putative 0.0076 0.0365 0.2243
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0175 0.1205
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0077 0.0427
Schistosoma mansoni coup transcription factor 0.002 0.0057 0.0062
Trypanosoma brucei unspecified product 0.0076 0.0365 0.2243
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Loa Loa (eye worm) intermediate filament protein 0.0057 0.026 0.028
Brugia malayi amine oxidase, flavin-containing family protein 0.0169 0.0869 0.2751
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0182 0.1087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0083
Trypanosoma brucei DNA polymerase IV, putative 0.0076 0.0365 0.2243
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0032 0.0126 0.1408
Echinococcus multilocularis musashi 0.0057 0.026 0.026
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0057 0.0179
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni lamin 0.0057 0.026 0.028
Mycobacterium ulcerans hypothetical protein 0.0023 0.0077 0.0371
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0057 0.0062
Leishmania major hypothetical protein, conserved 0.0108 0.0539 0.334
Entamoeba histolytica hypothetical protein 0.0131 0.066 0.6818
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0025 0.0085 0.0553
Trypanosoma cruzi DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Schistosoma mansoni synaptojanin 0.0032 0.0126 0.0135
Plasmodium falciparum glutathione reductase 0.0046 0.0199 0.2309
Brugia malayi Aldehyde dehydrogenase protein 4 0.0011 0.0009 0.0029
Echinococcus multilocularis lamin 0.0057 0.026 0.026
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0045 0.0143
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0057 0.0062
Leishmania major hypothetical protein, conserved 0.0032 0.0126 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Mycobacterium ulcerans DNA polymerase IV 0.0076 0.0365 0.1947
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0032 0.0126 0.0126
Loa Loa (eye worm) DR-78 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase eta, putative 0.0076 0.0365 0.2243
Echinococcus multilocularis dna polymerase eta 0.0076 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0044
Trypanosoma cruzi UDP-galactopyranose mutase 0.0124 0.0626 0.3886
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0093 0.0459 0.2831
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0199 0.1197
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0044 0.0187 0.1289
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0036 0.0172
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0036 0.0172
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0025 0.0085 0.0092
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0126 0.0135
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0007
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0025 0.0085 0.027
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0011 0.0009 0.001
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0159 0.0171
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0126 0.0135
Schistosoma mansoni DNA polymerase eta 0.0076 0.0365 0.0393
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0036
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.0009 0.001
Trypanosoma cruzi polo-like protein kinase, putative 0.0186 0.0964 0.6012
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0193 0.1335
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0098 0.0646
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0124 0.0626 0.7552
Echinococcus granulosus Chromobox protein 3 0.0011 0.0011 0.0012
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0045 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0121 0.0607 0.0652
Echinococcus granulosus dnaJ subfamily B 0.0403 0.2142 0.2304
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0626 0.7552
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0011 0.0009 0.0009
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0011 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0174 0.1036
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0186 0.0964 0.1037
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0253 0.1538
Entamoeba histolytica HEAT repeat domain containing protein 0.003 0.0116 0.1116
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.0365 0.1155
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0174 0.1202
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0021 0.0088
Leishmania major DNA polymerase kappa, putative 0.0024 0.0079 0.044
Loa Loa (eye worm) hypothetical protein 0.0032 0.0126 0.0135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0044 0.0254
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.0007 0.0007
Mycobacterium ulcerans monoamine oxidase 0.0124 0.0626 0.3374
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0057 0.0057
Brugia malayi nuclear hormone receptor family member nhr-6 0.0009 0.0001 0.0002
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0025 0.0085 0.027
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1719 0.9297 1
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0011 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0007 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0057 0.0181
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0011 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0174 0.1193
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0108 0.0539 0.334
Onchocerca volvulus Huntingtin homolog 0.0121 0.0607 0.1918
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0174 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0082 0.0531
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Trypanosoma cruzi PAB1-binding protein , putative 0.0108 0.0539 0.334
Toxoplasma gondii aldehyde dehydrogenase 0.0197 0.1023 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0044 0.0187 0.0589
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Schistosoma mansoni cript-related 0.0032 0.0126 0.0135
Schistosoma mansoni hypothetical protein 0.0028 0.0101 0.0108
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0197 0.1023 0.7403
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1223
Trypanosoma cruzi DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0015
Echinococcus multilocularis survival motor neuron protein 1 0.0508 0.2711 0.2711
Schistosoma mansoni hypothetical protein 0.001 0.0006 0.0007
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0025 0.0085 0.0553
Schistosoma mansoni chromobox protein 0.0011 0.0011 0.0012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0007 0.0007
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0011 0.0009 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0057 0.0057
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0033 0.0036
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0161 0.0161
Trichomonas vaginalis cdc25b, putative 0.0044 0.0187 0.1289
Trypanosoma brucei Monooxygenase, putative 0.0028 0.0101 0.0576
Brugia malayi Ets-domain containing protein 0.0071 0.0338 0.107
Plasmodium falciparum FAD-dependent monooxygenase, putative 0.0028 0.0101 0.1098
Onchocerca volvulus Serine\/threonine kinase homolog 0.0186 0.0964 0.3048
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0025 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0159 0.1089
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.1023 0.5542
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0029 0.0031
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0126 0.0398
Trypanosoma brucei DNA polymerase IV, putative 0.0076 0.0365 0.2243
Brugia malayi ecdysone receptor 0.0009 0.0001 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0036 0.0172
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0032 0.0126 0.1408
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0011 0.0015
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0079 0.044
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0025 0.0085 0.0092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0126 0.0135
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0025 0.0085 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0161 0.0173
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0011 0.0015
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0013 0.0042
Brugia malayi SET domain containing protein 0.0014 0.0024 0.0075
Leishmania major pantothenate kinase subunit, putative 0.0033 0.0131 0.0768
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0199 0.0214
Onchocerca volvulus 0.0025 0.0085 0.0268
Schistosoma mansoni monoxygenase 0.0028 0.0101 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1389 1
Brugia malayi Inositol-1 0.0072 0.0344 0.1087
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.016 0.0821 0.8501
Mycobacterium tuberculosis Possible oxidoreductase 0.0124 0.0626 0.4507
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0174 0.1202
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0263 0.1378 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.0214 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0011 0.0022
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0045 0.0413
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.016 0.0821 0.5111
Onchocerca volvulus 0.0025 0.0085 0.0268
Mycobacterium tuberculosis Conserved protein 0.0041 0.0174 0.1202
Treponema pallidum exodeoxyribonuclease (exoA) 0.016 0.0821 1
Loa Loa (eye worm) kap beta 3 protein 0.003 0.0116 0.0124
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1223
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0036 0.0172
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.0007 0.0007
Schistosoma mansoni nuclear hormone receptor 0.002 0.0057 0.0062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.001
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0011 0.0013
Brugia malayi beta-lactamase 0.0041 0.0174 0.0549
Echinococcus multilocularis neutral sphingomyelinase 0.0032 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.001 0.0006 0.0007
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0032 0.0126 0.0735
Schistosoma mansoni ets 0.001 0.0006 0.0007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.0001 0.0001
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0006 0.0007
Brugia malayi Heterochromatin protein 1 0.0069 0.0323 0.1023
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0128 0.0645 0.6276
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0236 0.1431
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0011 0.0009 0.0027
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0044 0.0187 0.0187
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0032 0.0126 0.0846
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0729 0.4537
Onchocerca volvulus 0.003 0.0114 0.0359
Echinococcus granulosus intermediate filament protein 0.0057 0.026 0.028
Mycobacterium ulcerans DNA polymerase IV 0.0076 0.0365 0.1947
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0032 0.0126 0.0735
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0033 0.013 0.014
Echinococcus multilocularis lamin dm0 0.0057 0.026 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Echinococcus granulosus protein MICAL 3 0.0028 0.0101 0.0108
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0036 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0186 0.0964 0.692
Schistosoma mansoni inositol monophosphatase 0.0072 0.0344 0.037
Loa Loa (eye worm) fli-1 protein 0.0217 0.1128 0.1214
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0057 0.0181
Entamoeba histolytica Ran family GTPase 0.0093 0.0459 0.4708
Echinococcus multilocularis synaptojanin 1 0.0032 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0365 0.2243
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0126 0.1151
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0264 0.0284
Brugia malayi mbt repeat family protein 0.0046 0.0201 0.0635
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0036 0.0115
Plasmodium falciparum importin beta, putative 0.0161 0.0826 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0579 0.3101 0.3336
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0025 0.0085 0.0092
Brugia malayi Pre-SET motif family protein 0.0031 0.0116 0.0368
Schistosoma mansoni survival motor neuron protein 0.0104 0.0513 0.0552
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0579 0.3101 0.3336
Loa Loa (eye worm) MBCTL1 0.0052 0.0235 0.0253
Loa Loa (eye worm) hypothetical protein 0.0124 0.0626 0.0674
Brugia malayi hypothetical protein 0.0011 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0101 0.0576
Entamoeba histolytica exodeoxyribonuclease III, putative 0.016 0.0821 0.8501
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0174 0.1202
Echinococcus multilocularis traf and tnf receptor associated protein 0.0032 0.0126 0.0126
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0044 0.0187 0.0201
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0006 0.0007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0161 0.0956
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0062
Echinococcus multilocularis importin 5 0.003 0.0116 0.0116
Schistosoma mansoni synaptojanin 0.0032 0.0126 0.0135
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0032 0.0126 0.0735
Loa Loa (eye worm) hypothetical protein 0.0048 0.0213 0.023
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0894 0.6414
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0009 0.0001 0.0001
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0126 0.0735
Entamoeba histolytica hypothetical protein 0.0045 0.0193 0.193
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0057 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1389 1
Leishmania major hypothetical protein, conserved 0.0028 0.0101 0.0576
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0011 0.0022
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0057 0.0062
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.069 0.0742
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0057 0.0179
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0945 0.6783
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0232 0.1406
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0076 0.0365 0.2243
Onchocerca volvulus 0.0298 0.157 0.4965
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.016 0.0821 0.994
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.005 0.0483
Brugia malayi serine/threonine-protein kinase plk-2 0.0186 0.0964 0.3049
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.0344 0.2426
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0077 0.0371
Trypanosoma brucei unspecified product 0.0053 0.0236 0.1431
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0072 0.0344 0.3301
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0235 0.0235
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0006 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0057 0.0057
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0174 0.1193
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 64 uM In vitro inhibition of procaryotic translation using Escherichia coli S30 Extract system for Circular DNA. ChEMBL. 12482431

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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