Detailed information for compound 107598

Basic information

Technical information
  • TDR Targets ID: 107598
  • Name: 7-[[(2Z)-2-(2-amino-5-chloro-1,3-thiazol-4-yl )-2-hydroxyiminoacetyl]amino]-3-[(4-aminopyri midin-2-yl)sulfanylmethylsulfanyl]-8-oxo-5-th ia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • MW: 575.065 | Formula: C17H15ClN8O5S4
  • H donors: 5 H acceptors: 8 LogP: 2.56 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: O/N=C(/c1nc(sc1Cl)N)\C(=O)NC1C(=O)N2C1SCC(=C2C(=O)O)SCSc1nccc(n1)N
  • InChi: 1S/C17H15ClN8O5S4/c18-11-7(24-16(20)35-11)8(25-31)12(27)23-9-13(28)26-10(15(29)30)5(3-32-14(9)26)33-4-34-17-21-2-1-6(19)22-17/h1-2,9,14,31H,3-4H2,(H2,20,24)(H,23,27)(H,29,30)(H2,19,21,22)/b25-8-
  • InChiKey: GLGZDFCPGWUNSH-JAHAZDFLSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 7-[[(2Z)-2-(2-amino-5-chloro-thiazol-4-yl)-2-hydroxyimino-acetyl]amino]-3-[(4-aminopyrimidin-2-yl)sulfanylmethylsulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-[[(2Z)-2-(2-amino-5-chloro-4-thiazolyl)-2-hydroxyimino-1-oxoethyl]amino]-3-[[(4-amino-2-pyrimidinyl)thio]methylthio]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-[[(2Z)-2-(2-azanyl-5-chloro-1,3-thiazol-4-yl)-2-hydroxyimino-ethanoyl]amino]-3-[(4-azanylpyrimidin-2-yl)sulfanylmethylsulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-[[(2Z)-2-(2-amino-5-chloro-thiazol-4-yl)-2-hydroximino-acetyl]amino]-3-[[(4-aminopyrimidin-2-yl)thio]methylthio]-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-[[(2Z)-2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-hydroxyimino-ethanoyl]amino]-3-[(4-aminopyrimidin-2-yl)sulfanylmethylsulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus cyclin B3 1 0.0241 0.0375 0.0456
Onchocerca volvulus 0.0127 0.0146 0.1312
Trypanosoma cruzi cyclin, putative 0.0422 0.0738 0.4855
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0391 0.0675 0.4443
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0044 0.0265
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0401 0.0695 0.1109
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0266 0.0423 0.8737
Echinococcus granulosus regulator of G protein signaling 7 0.0062 0.0014 0.0008
Onchocerca volvulus 0.0187 0.0266 0.245
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0422 0.0738 0.4858
Echinococcus granulosus membrane bound transcription factor site 1 0.0144 0.018 0.0214
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0104 0.01 0.0093
Echinococcus multilocularis regulator of G protein signaling 3 0.0062 0.0014 0.0018
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0228 0.0348 0.2278
Loa Loa (eye worm) hypothetical protein 0.0119 0.013 0.0202
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0401 0.0695 0.0855
Brugia malayi Cyclin, N-terminal domain containing protein 0.0241 0.0375 0.0595
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0401 0.0695 0.1109
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0254 0.0401 0.2625
Brugia malayi Trypsin family protein 0.0066 0.0024 0.0032
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0263 0.0419 0.2745
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0422 0.0738 0.4858
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0102 0.0095 0.0087
Loa Loa (eye worm) hypothetical protein 0.0058 0.0008 0.0006
Schistosoma mansoni hypothetical protein 0.0077 0.0045 0.0037
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0401 0.0695 0.0863
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Echinococcus granulosus cyclins 0.0241 0.0375 0.0456
Echinococcus granulosus ubiquitin specific protease 41 0.0076 0.0044 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0215 0.0321 0.0834
Loa Loa (eye worm) hypothetical protein 0.006 0.0011 0.0011
Brugia malayi G protein-coupled receptor F59B2.13 0.0401 0.0695 0.1109
Toxoplasma gondii sortilin, putative 0.0207 0.0306 0.4451
Loa Loa (eye worm) hypothetical protein 0.0223 0.0337 0.0535
Trypanosoma cruzi UDP-galactopyranose mutase 0.0104 0.01 0.0636
Brugia malayi aspartic protease BmAsp-1, identical 0.0119 0.013 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Leishmania major hypothetical protein, unknown function 0.0649 0.1192 0.7863
Trypanosoma brucei antigen, putative 0.0271 0.0435 0.285
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0401 0.0695 0.0688
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0108 0.0107 0.0133
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Echinococcus granulosus sortilin 0.0207 0.0306 0.0371
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0241 0.0375 0.0456
Echinococcus granulosus GPI anchor transamidase 0.006 0.0011 0.0004
Echinococcus multilocularis cyclin y 0.0058 0.0008 0.0009
Entamoeba histolytica chitinase, putative 0.0307 0.0507 0.6857
Leishmania major receptor-type adenylate cyclase a-like protein 0.0263 0.0419 0.2745
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0177 0.0245 0.1596
Brugia malayi Trypsin-like protease protein 5 0.0066 0.0024 0.0032
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0125 0.0141 0.0358
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0153 0.0198 0.1283
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0072 0.0035 0.0027
Trichomonas vaginalis cyclins, putative 0.0241 0.0375 0.0975
Toxoplasma gondii cathepsin CPC2 0.0386 0.0665 0.9746
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0401 0.0695 0.0688
Loa Loa (eye worm) RGS-3 protein 0.0062 0.0014 0.0016
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0107 0.0124
Schistosoma mansoni neuropeptide receptor 0.0401 0.0695 0.0688
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0395 0.0682 0.4488
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0401 0.0695 0.0688
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0014 0.0024
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0129 0.015 0.0966
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Plasmodium vivax subtilisin-like protease 1 0.0144 0.018 0.2549
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0395 0.0682 0.4488
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.0266 0.3572
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0266 0.0423 0.0673
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0021 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0146 0.0372
Echinococcus granulosus tm gpcr rhodopsin 0.4071 0.8055 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0357 0.0606 0.3986
Brugia malayi Cathepsin L-like precursor 0.0187 0.0266 0.042
Echinococcus multilocularis neuropeptides capa receptor 0.0401 0.0695 0.0863
Schistosoma mansoni hypothetical protein 0.2405 0.4714 0.471
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.0035 0.0027
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.01 0.0092 0.0084
Brugia malayi ORL1-like opioid receptor 0.0401 0.0695 0.1109
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0422 0.0738 0.4855
Loa Loa (eye worm) G-protein coupled receptor 0.0401 0.0695 0.1109
Schistosoma mansoni axis inhibition protein axin 0.0062 0.0014 0.0007
Entamoeba histolytica peptidase, C54 family 0.0081 0.0052 0.0658
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0456 0.0806 0.5307
Echinococcus multilocularis integrin alpha ps 0.0276 0.0445 0.0552
Loa Loa (eye worm) hypothetical protein 0.007 0.003 0.0042
Schistosoma mansoni memapsin-2 (A01 family) 0.0933 0.1761 0.1755
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.007 0.0031 0.0024
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0401 0.0695 0.0688
Brugia malayi SWIRM domain containing protein 0.0558 0.1009 0.1612
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0111 0.0113 0.014
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.0401 0.0695 0.0863
Echinococcus multilocularis axis inhibition protein axin 0.0062 0.0014 0.0018
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.007 0.003 0.0376
Plasmodium falciparum calpain 0.0234 0.0359 0.523
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0107 0.0133
Loa Loa (eye worm) PXA domain-containing protein 0.0062 0.0014 0.0016
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0062 0.0014 0.0007
Echinococcus granulosus calpain A 0.0271 0.0435 0.0531
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0125 0.0141 0.0358
Plasmodium vivax aspartyl protease, putative 0.0119 0.013 0.1814
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.0406 0.2658
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0263 0.0419 0.2745
Schistosoma mansoni endothelin-converting enzyme-related 0.0072 0.0035 0.0027
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0263 0.0419 0.2745
Trypanosoma cruzi cyclin, putative 0.0422 0.0738 0.4855
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0401 0.0695 0.1109
Brugia malayi putative neuropeptide receptor 0.0401 0.0695 0.1109
Trypanosoma brucei calpain-like protein, putative 0.0271 0.0435 0.285
Trichomonas vaginalis cyclin A, putative 0.0058 0.0008 0.0007
Brugia malayi endochitinase 0.0307 0.0507 0.0807
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0108 0.0107 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0234 0.0359 0.523
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0395 0.0682 0.1088
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0018 0.0188
Trypanosoma brucei Aminopeptidase M1, putative 0.0108 0.0107 0.0684
Trichomonas vaginalis cyclin D, putative 0.0241 0.0375 0.0975
Brugia malayi CG8232-PA 0.0058 0.0008 0.0006
Echinococcus multilocularis integrin alpha ps 0.0132 0.0156 0.0194
Schistosoma mansoni hypothetical protein 0.0132 0.0156 0.0149
Echinococcus granulosus aminopeptidase N 0.0367 0.0627 0.077
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.023 0.0352 0.4737
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Brugia malayi Cathepsin L-like precursor 0.0187 0.0266 0.042
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0113 0.1481
Schistosoma mansoni regulator of G protein signaling 0.0062 0.0014 0.0007
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0062 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0104 0.01 0.0154
Echinococcus granulosus fmrfamide receptor 0.0401 0.0695 0.0855
Trichomonas vaginalis cyclin B, putative 0.0422 0.0738 0.1931
Entamoeba histolytica hypothetical protein 0.0062 0.0014 0.0137
Leishmania major hypothetical protein, conserved 0.0426 0.0745 0.4904
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0021 0.0111
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0215 0.0321 0.0834
Brugia malayi celfurPC protein 0.2513 0.4931 0.7903
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.007 0.003 0.0023
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0528 0.0949 0.6259
Brugia malayi hypothetical protein 0.0108 0.0107 0.0166
Trichomonas vaginalis cyclin B3, putative 0.0058 0.0008 0.0007
Schistosoma mansoni calpain C (C02 family) 0.0271 0.0435 0.0427
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0107 0.0124
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0401 0.0695 0.0855
Brugia malayi Serotonin receptor 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.007 0.003 0.0042
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0294 0.0481 0.0765
Onchocerca volvulus 0.0105 0.0101 0.0889
Echinococcus multilocularis calpain family protein 1, d 0.0215 0.0321 0.0399
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0478 0.0849 0.5595
Brugia malayi GnHR receptor homolog 0.0401 0.0695 0.1109
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0478 0.0849 0.5595
Plasmodium vivax subtilisin-like serine protease, putative 0.0144 0.018 0.2549
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0401 0.0695 0.0863
Trichomonas vaginalis cyclins, putative 0.0422 0.0738 0.1931
Plasmodium falciparum plasmepsin II 0.0395 0.0682 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0266 0.0423 0.2776
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0066 0.0024 0.002
Trypanosoma cruzi cysteine peptidase inhibitor 0.023 0.0352 0.23
Brugia malayi endochitinase 0.0307 0.0507 0.0807
Leishmania major hypothetical protein, conserved 0.0328 0.0549 0.3606
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Loa Loa (eye worm) hypothetical protein 0.0104 0.01 0.0154
Trypanosoma brucei trypanothione synthetase, putative 0.0066 0.0023 0.0128
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0514 0.0922 0.0915
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0595 0.1084 0.715
Echinococcus granulosus G protein coupled receptor 139 0.0401 0.0695 0.0855
Onchocerca volvulus 0.0401 0.0695 0.652
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0273 0.0439 0.2877
Echinococcus multilocularis Cyclin L1 0.0058 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0133 0.0158 0.0246
Onchocerca volvulus 0.0401 0.0695 0.652
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0048 0.0293
Toxoplasma gondii subtilisin SUB5 0.0144 0.018 0.2578
Trichomonas vaginalis cyclin B3, putative 0.0058 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0144 0.018 0.0281
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Schistosoma mansoni sortilin 0.0147 0.0185 0.0178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0619 0.1132 0.7465
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0401 0.0695 0.0863
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0044 0.0265
Plasmodium falciparum plasmepsin X 0.0119 0.013 0.1846
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0228 0.0348 0.2278
Loa Loa (eye worm) cyclin C 0.0058 0.0008 0.0006
Echinococcus multilocularis cathepsin L 0.0099 0.009 0.0112
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.081 0.1515 1
Echinococcus granulosus tm gpcr rhodopsin 0.0401 0.0695 0.0855
Onchocerca volvulus 0.0584 0.1062 1
Trichomonas vaginalis cyclin B, putative 0.0422 0.0738 0.1931
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0111 0.0113 0.0174
Echinococcus granulosus integrin alpha 3 0.0472 0.0838 0.1032
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0386 0.0665 0.9745
Toxoplasma gondii aspartyl protease 0.0119 0.013 0.1846
Leishmania major small myristoylated protein-3, putative 0.0357 0.0606 0.3986
Brugia malayi CHE-14 protein 0.0109 0.011 0.017
Schistosoma mansoni neuropeptide f receptor 76f 0.0401 0.0695 0.0688
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0014 0.0024
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0266 0.0423 0.0526
Brugia malayi Myb-like DNA-binding domain containing protein 0.0189 0.027 0.0426
Trypanosoma cruzi cysteine peptidase, putative 0.0326 0.0544 0.3577
Echinococcus granulosus neuropeptides capa receptor 0.0401 0.0695 0.0855
Echinococcus granulosus serotonin receptor 0.0401 0.0695 0.0855
Brugia malayi neuropeptide F receptor 0.0401 0.0695 0.1109
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Trypanosoma cruzi UDP-galactopyranose mutase 0.0104 0.01 0.0636
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0395 0.0682 0.0847
Echinococcus multilocularis integrin alpha ps 0.0276 0.0445 0.0552
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0062 0.0014 0.0016
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.011 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0008 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0062 0.0014 0.0007
Schistosoma mansoni amine oxidase 0.0104 0.01 0.0093
Echinococcus granulosus 7TM GPCR rhodopsin 0.0401 0.0695 0.0855
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0104 0.01 0.1668
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0257 0.0406 0.2658
Schistosoma mansoni amine GPCR 0.0401 0.0695 0.0688
Leishmania major cysteine peptidase A (CPA) 0.0187 0.0266 0.1734
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0066 0.0024 0.003
Trypanosoma cruzi small myristoylated protein 1-2 0.041 0.0713 0.4695
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0008 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0796 0.1487 0.3906
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Echinococcus multilocularis Peptidase C54 0.0081 0.0052 0.0065
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Onchocerca volvulus 0.0401 0.0695 0.652
Schistosoma mansoni biogenic amine (5HT) receptor 0.0401 0.0695 0.0688
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.007 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0649 0.1192 0.7863
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0401 0.0695 0.0863
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0146 0.0183 0.0287
Brugia malayi Cathepsin L-like precursor 0.0187 0.0266 0.042
Loa Loa (eye worm) subtilase 0.0144 0.018 0.0281
Echinococcus multilocularis cyclin 0.0058 0.0008 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.01 0.0092 0.0084
Toxoplasma gondii subtilisin SUB6 0.0144 0.018 0.2578
Schistosoma mansoni calpain-7 (C02 family) 0.0345 0.0583 0.0576
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0652 0.1198 0.3145
Leishmania major small myristoylated protein 4, putative 0.0611 0.1117 0.7367
Toxoplasma gondii hypothetical protein 0.0183 0.0258 0.3737
Leishmania major hypothetical protein, conserved 0.0066 0.0023 0.0128
Entamoeba histolytica cysteine proteinase 1, putative 0.0099 0.009 0.1171
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0587 0.1069 0.7047
Schistosoma mansoni cyclin B3 0.0241 0.0375 0.0368
Mycobacterium ulcerans hypothetical protein 0.0097 0.0086 0.1352
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0611 0.1117 0.7367
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0144 0.018 0.0172
Brugia malayi GPI-anchor transamidase 0.006 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.01 0.0092 0.058
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0111 0.0113 0.1591
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0149 0.0189 0.0181
Mycobacterium ulcerans oxidoreductase 0.0104 0.01 0.1668
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0149 0.0189 0.0181
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0062 0.0014 0.0007
Echinococcus granulosus lysine specific histone demethylase 1A 0.0104 0.01 0.0115
Loa Loa (eye worm) hypothetical protein 0.007 0.0031 0.0044
Schistosoma mansoni opsin-like receptor 0.0401 0.0695 0.0688
Schistosoma mansoni hypothetical protein 0.0215 0.0321 0.0314
Loa Loa (eye worm) hypothetical protein 0.0558 0.1009 0.1612
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0584 0.1062 0.1056
Loa Loa (eye worm) hypothetical protein 0.0294 0.0481 0.0765
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) microfilarial chitinase 0.0262 0.0416 0.0661
Loa Loa (eye worm) neuropeptide F receptor 0.0401 0.0695 0.1109
Entamoeba histolytica aminopeptidase, putative 0.0108 0.0107 0.1409
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0063 0.0018 0.0022
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Loa Loa (eye worm) hypothetical protein 0.0076 0.0044 0.0064
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Schistosoma mansoni cathepsin F (C01 family) 0.0127 0.0146 0.0139
Loa Loa (eye worm) cuticular endochitinase 0.0307 0.0507 0.0807
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0111 0.0113 0.1559
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0129 0.015 0.0143
Onchocerca volvulus 0.0066 0.0024 0.0156
Brugia malayi Integrin alpha pat-2 precursor 0.0616 0.1127 0.1801
Mycobacterium leprae Possible secreted protease 0.0144 0.018 0.2083
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0177 0.0245 0.0386
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0144 0.018 0.0172
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.006 0.0011 0.0016
Schistosoma mansoni myosin xvIII 0.0401 0.0695 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.0864 0.0858
Plasmodium vivax unspecified product 0.006 0.0011 0.0048
Brugia malayi neuroendocrine convertase 1 precursor 0.2012 0.3926 0.6292
Entamoeba histolytica cyclin, domain containing protein 0.0058 0.0008 0.0047
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.006 0.0369
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0048 0.0115
Trypanosoma cruzi aminopeptidase, putative 0.0108 0.0107 0.0684
Echinococcus multilocularis g protein coupled receptor 0.0401 0.0695 0.0863
Trypanosoma brucei hypothetical protein 0.0471 0.0836 0.5508
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0241 0.0375 0.0465
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.007 0.003 0.0174
Echinococcus granulosus sex peptide receptor 0.0401 0.0695 0.0855
Echinococcus multilocularis regulator of G protein signaling 0.0062 0.0014 0.0018
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0122 0.0136 0.0129
Brugia malayi AKH receptor 0.0401 0.0695 0.1109
Echinococcus multilocularis dnaJ subfamily B 0.2405 0.4714 0.5852
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.023 0.0352 0.23
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0115 0.0121 0.0188
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0401 0.0695 0.1109
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0181 0.0174
Entamoeba histolytica cyclin C, putative 0.0058 0.0008 0.0047
Onchocerca volvulus 0.0401 0.0695 0.652
Plasmodium vivax aspartyl proteinase, putative 0.0395 0.0682 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trypanosoma cruzi cyclin 9, putative 0.0058 0.0008 0.0023
Loa Loa (eye worm) CYL-1 protein 0.0058 0.0008 0.0006
Echinococcus granulosus allatostatin A receptor 0.0401 0.0695 0.0855
Toxoplasma gondii cyclin 4, putative 0.0058 0.0008 0.0039
Brugia malayi Trypsin family protein 0.0066 0.0024 0.0032
Echinococcus granulosus biogenic amine 5HT receptor 0.0401 0.0695 0.0855
Echinococcus granulosus expressed protein 0.0791 0.1478 0.1827
Trichomonas vaginalis cyclin A, putative 0.0422 0.0738 0.1931
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.0406 0.2658
Schistosoma mansoni biogenic amine receptor 0.0401 0.0695 0.0688
Loa Loa (eye worm) hypothetical protein 0.0329 0.0551 0.0877
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0401 0.0695 0.0688
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0228 0.0348 0.2278
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0024 0.0016
Echinococcus granulosus integrin alpha ps 0.0276 0.0445 0.0543
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0395 0.0682 0.0838
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0401 0.0695 0.0863
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Echinococcus multilocularis Regulator of G protein signaling 20 0.0062 0.0014 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.009 0.1171
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0144 0.018 0.3403
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0207 0.0306 0.1999
Onchocerca volvulus 0.0108 0.0107 0.0947
Loa Loa (eye worm) hypothetical protein 0.0584 0.1062 0.1698
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0649 0.1192 0.7863
Trypanosoma cruzi trypanothione synthetase, putative 0.0066 0.0023 0.0128
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0058 0.0008 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0401 0.0695 0.0863
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.003 0.0174
Loa Loa (eye worm) calpain 0.0302 0.0497 0.0791
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0119 0.013 0.1846
Onchocerca volvulus CoRest homolog 0.0195 0.0281 0.2591
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0108 0.0107 0.0684
Onchocerca volvulus 0.0401 0.0695 0.652
Trypanosoma brucei cyclin 9 0.0058 0.0008 0.0023
Toxoplasma gondii hypothetical protein 0.0215 0.0321 0.467
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0104 0.01 0.1373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.081 0.1515 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0107 0.0133
Onchocerca volvulus 0.0119 0.013 0.116
Schistosoma mansoni cyclins 0.0241 0.0375 0.0368
Brugia malayi Cathepsin L-like precursor 0.0187 0.0266 0.042
Loa Loa (eye worm) TYRA-2 protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0058 0.0008 0.0039
Brugia malayi Kringle domain containing protein 0.0133 0.0158 0.0246
Leishmania major small myristoylated protein-1 0.041 0.0713 0.4695
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0558 0.101 0.6661
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Echinococcus granulosus cyclins 0.0241 0.0375 0.0456
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0641 0.1176 0.776
Onchocerca volvulus 0.0422 0.0738 0.692
Loa Loa (eye worm) hypothetical protein 0.0195 0.0281 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0008 0.0007
Schistosoma mansoni histamine h1 receptor 0.0401 0.0695 0.0688
Loa Loa (eye worm) hypothetical protein 0.0271 0.0435 0.0691
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0652 0.1198 0.3145
Trypanosoma brucei conserved protein 0.0211 0.0314 0.2054
Leishmania major hypothetical protein, conserved 0.0133 0.0158 0.1016
Echinococcus multilocularis cysteine protease 0.0187 0.0266 0.033
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.01 0.0092 0.058
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0266 0.0424 0.2782
Echinococcus granulosus cyclins 0.0241 0.0375 0.0456
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0122 0.0136 0.0876
Onchocerca volvulus 0.0119 0.013 0.116
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0111 0.0113 0.0105
Echinococcus multilocularis G-protein coupled receptor, putative 0.0401 0.0695 0.0863
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0107 0.0133
Echinococcus granulosus calpain 0.0271 0.0435 0.0531
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0076 0.0043 0.0062
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0584 0.1062 0.1056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Leishmania major hypothetical protein, conserved 0.0263 0.0419 0.2745
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Schistosoma mansoni cathepsin F (C01 family) 0.0187 0.0266 0.0259
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0063 0.0018 0.0185
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0641 0.1176 0.776
Echinococcus granulosus orexin receptor type 2 0.0401 0.0695 0.0855
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0401 0.0695 0.0855
Entamoeba histolytica hypothetical protein 0.0062 0.0014 0.0137
Brugia malayi Cyclin C 0.0058 0.0008 0.0006
Trypanosoma cruzi cruzipain precursor, putative 0.006 0.0011 0.0044
Trypanosoma cruzi trypanothione synthetase 0.0066 0.0023 0.0128
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0144 0.018 0.2083
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0081 0.0052 0.0045
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0024 0.0016
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0058 0.0008 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0122 0.0136 0.0212
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.003 0.0338
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0158 0.1016
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0149 0.0189 0.0181
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Plasmodium vivax sortilin, putative 0.0207 0.0306 0.443
Toxoplasma gondii subtilisin SUB1 0.0144 0.018 0.2578
Loa Loa (eye worm) hypothetical protein 0.0119 0.013 0.0202
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0081 0.0052 0.0125
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0081 0.0052 0.0125
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Loa Loa (eye worm) neuropeptide F receptor 0.0401 0.0695 0.1109
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0395 0.0682 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0102 0.0095 0.0109
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi peptidase family M13 containing protein 0.0072 0.0035 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Loa Loa (eye worm) hypothetical protein 0.0218 0.0327 0.0518
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0129 0.015 0.0382
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0187 0.0266 0.033
Loa Loa (eye worm) cyclin domain-containing protein 0.0058 0.0008 0.0006
Brugia malayi hypothetical protein 0.0062 0.0014 0.0016
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0102 0.0095 0.0146
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0271 0.0435 0.0427
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0061 0.0012 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0104 0.01 0.1373
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni neuropeptide F-like receptor 0.0401 0.0695 0.0688
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0077 0.0045 0.0037
Entamoeba histolytica cyclin family protein 0.0241 0.0375 0.5055
Plasmodium vivax subtilisin-like protease 2, putative 0.0144 0.018 0.2549
Echinococcus granulosus Furin 1 0.0796 0.1487 0.1838
Leishmania major trypanothione synthetase, putative 0.0066 0.0023 0.0128
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0044 0.0045
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0228 0.0348 0.2278
Entamoeba histolytica cysteine proteinase, putative 0.0127 0.0146 0.1935
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Echinococcus granulosus epidermal growth factor receptor 0.0374 0.064 0.0786
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0125 0.0141 0.0358
Schistosoma mansoni site-1 peptidase (S08 family) 0.0144 0.018 0.0172
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.0266 0.3572
Brugia malayi Peptidase family M1 containing protein 0.0108 0.0107 0.0166
Trypanosoma cruzi cysteine proteinase, putative 0.0099 0.009 0.0568
Echinococcus multilocularis serotonin receptor 0.0401 0.0695 0.0863
Echinococcus granulosus regulator of G protein signaling 3 0.0062 0.0014 0.0008
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0263 0.0419 0.2745
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0641 0.1176 0.776
Schistosoma mansoni amine GPCR 0.0401 0.0695 0.0688
Trypanosoma cruzi cysteine protease, putative 0.0099 0.009 0.0568
Brugia malayi Papain family cysteine protease containing protein 0.0187 0.0266 0.042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Echinococcus granulosus tissue type plasminogen activator 0.0133 0.0158 0.0186
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0144 0.018 0.2083
Trichomonas vaginalis cyclin D, putative 0.0058 0.0008 0.0007
Loa Loa (eye worm) cyclin domain-containing protein 0.0058 0.0008 0.0006
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0111 0.0113 0.1591
Toxoplasma gondii subtilisin SUB9 0.0144 0.018 0.2578
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0048 0.0293
Echinococcus granulosus g protein coupled receptor 0.0401 0.0695 0.0855
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0102 0.0095 0.0118
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0097 0.0085 0.0097
Echinococcus multilocularis neuroendocrine convertase 2 0.2012 0.3926 0.4874
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.018 0.046
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0044 0.0055
Schistosoma mansoni glutamate receptor NMDA 0.0259 0.0409 0.0402
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.0419 0.2745
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.009 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.011 0.0277
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0273 0.0439 0.2877
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0043 0.01
Schistosoma mansoni amine oxidase 0.0104 0.01 0.0093
Echinococcus granulosus neuropeptide s receptor 0.0866 0.1627 0.2012
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0263 0.0419 0.2745
Echinococcus granulosus neuropeptide receptor 0.0401 0.0695 0.0855
Onchocerca volvulus Putative endochitinase 0.0307 0.0507 0.4735
Brugia malayi calpain 5 0.0215 0.0321 0.0509
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0104 0.01 0.1407
Entamoeba histolytica peptidase, C54 family 0.0192 0.0276 0.3706
Trypanosoma cruzi CYC2-like cyclin, putative 0.0422 0.0738 0.4855
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0215 0.0321 0.0834
Plasmodium falciparum cyclin 0.0241 0.0375 0.5462
Loa Loa (eye worm) hypothetical protein 0.034 0.0572 0.0912
Loa Loa (eye worm) hypothetical protein 0.0294 0.0481 0.0765
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0104 0.01 0.1668
Echinococcus multilocularis neuropeptide FF receptor 2 0.0879 0.1654 0.2054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Echinococcus multilocularis GPI anchor transamidase 0.006 0.0011 0.0014
Trypanosoma brucei inhibitor of cysteine peptidase 0.023 0.0352 0.23
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0401 0.0695 0.0688
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0102 0.0095 0.0601
Schistosoma mansoni serine-type protease inhibitor 0.3988 0.7889 0.7887
Mycobacterium tuberculosis Conserved hypothetical protein 0.0104 0.01 0.1197
Onchocerca volvulus 0.0066 0.0024 0.0156
Brugia malayi Cathepsin L-like precursor 0.006 0.0011 0.0011
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0187 0.0266 0.3855
Echinococcus granulosus cyclins 0.0241 0.0375 0.0456
Schistosoma mansoni cathepsin D (A01 family) 0.0958 0.1812 0.1806
Trypanosoma cruzi cysteine peptidase, putative 0.0099 0.009 0.0568
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0187 0.0266 0.033
Loa Loa (eye worm) hypothetical protein 0.1217 0.233 0.3732
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0271 0.0435 0.0427
Giardia lamblia Cathepsin B precursor 0.01 0.0092 0.0384
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0471 0.0836 0.5508
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0021 0.0026
Echinococcus granulosus hypothetical protein 0.0401 0.0695 0.0855
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0294 0.0481 0.0474
Trichomonas vaginalis cyclins, putative 0.0422 0.0738 0.1931
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0471 0.0836 0.5508
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0552 0.0997 0.6573
Onchocerca volvulus 0.0187 0.0266 0.245
Loa Loa (eye worm) calpain family protein 1 0.0215 0.0321 0.0509
Brugia malayi cathepsin F-like cysteine proteinase 0.006 0.0011 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Loa Loa (eye worm) hypothetical protein 0.0484 0.0861 0.1375
Schistosoma mansoni otubain-1 (C65 family) 0.0084 0.006 0.0052
Entamoeba histolytica cysteine protease, putative 0.0187 0.0266 0.3572
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0144 0.0179 0.0281
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0652 0.1198 0.3145
Echinococcus granulosus neuroendocrine convertase 2 0.2012 0.3926 0.487
Trypanosoma cruzi cysteine proteinase, putative 0.0099 0.009 0.0568
Echinococcus multilocularis g protein coupled receptor 0.0401 0.0695 0.0863
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0175 0.0241 0.0233
Echinococcus granulosus tm gpcr rhodopsin 0.0401 0.0695 0.0855
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0192 0.0276 0.18
Echinococcus multilocularis enteropeptidase 0.0066 0.0024 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Trypanosoma cruzi small myristoylated protein 1-1 0.041 0.0713 0.4695
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0357 0.0606 0.3986
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.009 0.1171
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0145 0.0181 0.0284
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.006 0.0011 0.0011
Trypanosoma brucei Calpain-like protein 2 0.0601 0.1097 0.7233
Toxoplasma gondii histone lysine-specific demethylase 0.0104 0.01 0.1407
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Echinococcus multilocularis Furin 1 0.0796 0.1487 0.1846
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0079 0.0048 0.0604
Schistosoma mansoni biogenic amine receptor 0.0401 0.0695 0.0688
Leishmania major cyclin 0.0422 0.0738 0.4855
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Echinococcus granulosus peptide allatostatin:somatostatin 0.0401 0.0695 0.0855
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Brugia malayi Dopamine receptor protein 2 0.0401 0.0695 0.1109
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0108 0.0107 0.0684
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0021 0.0111
Echinococcus multilocularis glycoprotein Antigen 5 0.0066 0.0024 0.003
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0215 0.0321 0.21
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Echinococcus granulosus cyclin b3 0.0241 0.0375 0.0456
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0081 0.0052 0.0125
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0266 0.0423 0.0517
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.01 0.0092 0.058
Entamoeba histolytica hypothetical protein 0.0058 0.0008 0.0047
Brugia malayi Peptidase family C54 containing protein 0.0081 0.0052 0.0077
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0587 0.1069 0.7047
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.04 0.0692 0.4557
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0043 0.01
Echinococcus granulosus 7tm_1 domain containing protein 0.0401 0.0695 0.0855
Echinococcus granulosus cathepsin l cysteine peptidase 0.0187 0.0266 0.0321
Trypanosoma cruzi Aminopeptidase M1, putative 0.0108 0.0107 0.0684
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Mycobacterium tuberculosis Possible oxidoreductase 0.0104 0.01 0.1197
Loa Loa (eye worm) hypothetical protein 0.0259 0.041 0.0652
Loa Loa (eye worm) hypothetical protein 0.0062 0.0014 0.0016
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0058 0.0008 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0328 0.0549 0.3606
Loa Loa (eye worm) integrin beta-2 0.1589 0.3078 0.4932
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0071 0.0034 0.0198
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0083 0.0058 0.0072
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0254 0.0401 0.2625
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0097 0.0085 0.0538
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.006 0.0011 0.0003
Schistosoma mansoni site-1 peptidase (S08 family) 0.0144 0.018 0.0172
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0079 0.0048 0.0041
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0099 0.009 0.0568
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.081 0.1515 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0099 0.009 0.0568
Plasmodium vivax plasmepsin IV, putative 0.0395 0.0682 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.006 0.0011 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0071 0.0034 0.0077
Brugia malayi G protein-coupled receptor 0.0401 0.0695 0.1109
Brugia malayi Regulator of G protein signaling domain containing protein 0.0062 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trypanosoma cruzi conserved protein 0.0426 0.0745 0.4904
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0422 0.0738 0.4858
Schistosoma mansoni hypothetical protein 0.0077 0.0045 0.0037
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0243 0.0379 0.0601
Brugia malayi Cyclin, N-terminal domain containing protein 0.0422 0.0738 0.1177
Schistosoma mansoni opsin-like receptor 0.0401 0.0695 0.0688
Loa Loa (eye worm) TK/EGFR protein kinase 0.0374 0.064 0.1021
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Plasmodium falciparum subtilisin-like protease 1 0.0144 0.018 0.2578
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0228 0.0348 0.2278
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.009 0.1171
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0072 0.0035 0.0027
Brugia malayi Serotonin receptor 0.0401 0.0695 0.1109
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0796 0.1487 0.148
Plasmodium falciparum plasmepsin I 0.0395 0.0682 1
Leishmania major cathepsin L-like protease 0.0187 0.0266 0.1734
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0063 0.0018 0.009
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0104 0.01 0.1668
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Brugia malayi cyclin fold protein 1 variant b 0.0058 0.0008 0.0006
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0917 0.1729 0.1723
Loa Loa (eye worm) TK/ROR protein kinase 0.0133 0.0158 0.0246
Leishmania major cathepsin L-like protease 0.0326 0.0544 0.3577
Toxoplasma gondii subtilisin SUB11 0.0144 0.018 0.2578
Echinococcus granulosus G protein coupled receptor kinase 1 0.0083 0.0058 0.0062
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0528 0.0949 0.6259
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0111 0.0113 0.0105
Toxoplasma gondii aspartyl protease ASP1 0.0395 0.0682 1
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0108 0.0107 0.0684
Echinococcus granulosus neuropeptide Y receptor 0.0401 0.0695 0.0855
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0192 0.0276 0.18
Loa Loa (eye worm) hypothetical protein 0.0109 0.011 0.017
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0558 0.101 0.6661
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0097 0.0085 0.0212
Brugia malayi cathepsin B-like cysteine proteinase 0.01 0.0092 0.0141
Trypanosoma cruzi cysteine peptidase, putative 0.006 0.0011 0.0044
Leishmania major cathepsin L-like protease 0.0187 0.0266 0.1734
Leishmania major small myristoylated protein-2 0.0697 0.1289 0.8509
Echinococcus multilocularis protoporphyrinogen oxidase 0.0104 0.01 0.0124
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0107 0.0124
Echinococcus multilocularis neuropeptide s receptor 0.0866 0.1627 0.202
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus granulosus sterol regulatory element binding protein 0.0109 0.011 0.0127
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0097 0.0085 0.0538
Echinococcus granulosus alpha 1A adrenergic receptor 0.0401 0.0695 0.0855
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi hypothetical protein 0.0062 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Echinococcus granulosus ubiquitin specific peptidase c family 0.0129 0.015 0.0177
Loa Loa (eye worm) integrin alpha pat-2 0.095 0.1796 0.2874
Toxoplasma gondii subtilisin SUB7 0.0144 0.018 0.2578
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0079 0.0048 0.0534
Plasmodium vivax aspartyl protease, putative 0.0119 0.013 0.1814
Schistosoma mansoni amine GPCR 0.0401 0.0695 0.0688
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.006 0.001 0.0041
Schistosoma mansoni cathepsin D (A01 family) 0.0958 0.1812 0.1806
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0071 0.0034 0.0026
Loa Loa (eye worm) hypothetical protein 0.0181 0.0253 0.04
Trypanosoma brucei cysteine peptidase, putative 0.0558 0.101 0.6661
Plasmodium falciparum plasmepsin VI 0.0395 0.0682 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0092 0.0141
Echinococcus multilocularis regulator of G protein signaling 7 0.0062 0.0014 0.0018
Echinococcus granulosus glycoprotein Antigen 5 0.0066 0.0024 0.002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0619 0.1132 0.7465
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) peptidase family M13 containing protein 0.0218 0.0327 0.0518
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0257 0.0406 0.2658
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Echinococcus multilocularis cyclin G2 0.0058 0.0008 0.0009
Brugia malayi Kelch motif family protein 0.0243 0.0379 0.0601
Brugia malayi hypothetical protein 0.0066 0.0024 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Loa Loa (eye worm) G-protein coupled receptor 0.0401 0.0695 0.1109
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0168 0.0227 0.4128
Trypanosoma cruzi hypothetical protein, conserved 0.0328 0.0549 0.3606
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0401 0.0695 0.1109
Echinococcus multilocularis Mastin 0.0066 0.0024 0.003
Echinococcus granulosus neuropeptide receptor 0.0858 0.1611 0.1993
Leishmania major calpain protease-like protein 0.0246 0.0384 0.2513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Giardia lamblia GPI-anchor transamidase, putative 0.006 0.0011 0.0015
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0144 0.018 0.3403
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0062 0.0014 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0062 0.0014 0.0007
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0401 0.0695 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0044 0.0103
Echinococcus multilocularis cyclin G2 0.0058 0.0008 0.0009
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0111 0.0113 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Loa Loa (eye worm) hypothetical protein 0.006 0.0011 0.0011
Trichomonas vaginalis cyclin D, putative 0.0241 0.0375 0.0975
Giardia lamblia G2/mitotic-specific cyclin B 0.0422 0.0738 0.3326
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0066 0.0023 0.0128
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.01 0.0092 0.0084
Leishmania major META domain containing protein 0.0263 0.0419 0.2745
Echinococcus granulosus dro:myosuppressin receptor 0.0401 0.0695 0.0855
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0113 0.0719
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0079 0.0048 0.5
Brugia malayi Eukaryotic aspartyl protease family protein 0.0119 0.013 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0456 0.0806 0.5307
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0401 0.0695 0.0855
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0071 0.0034 0.0198
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Echinococcus multilocularis neuropeptide receptor 0.0401 0.0695 0.0863
Trypanosoma cruzi cysteine peptidase, putative 0.0326 0.0544 0.3577
Brugia malayi Melatonin receptor type 1A 0.0401 0.0695 0.1109
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0767 0.143 0.9438
Trypanosoma brucei hypothetical protein, conserved 0.0328 0.0549 0.3606
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0528 0.0949 0.6259
Brugia malayi follicle stimulating hormone receptor 0.0401 0.0695 0.1109
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0163 0.0218 0.1414
Trypanosoma brucei trypanothione synthetase 0.0066 0.0023 0.0128
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.006 0.0011 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Echinococcus granulosus Peptidase C54 0.0081 0.0052 0.0056
Trypanosoma brucei cysteine peptidase C (CPC) 0.01 0.0092 0.058
Giardia lamblia Furin precursor putative serine protease 0.0652 0.1198 0.5424
Brugia malayi calpain D 0.0282 0.0457 0.0726
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0144 0.018 0.0281
Echinococcus granulosus axis inhibition protein axin 0.0062 0.0014 0.0008
Brugia malayi Cathepsin L-like cysteine proteinase 0.0127 0.0146 0.0228
Echinococcus granulosus cathepsin l1 0.0187 0.0266 0.0321
Echinococcus multilocularis neuropeptide receptor 0.0858 0.1611 0.2
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0395 0.0682 0.0675
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.011 0.0127
Loa Loa (eye worm) endoprotease bli-4 0.3165 0.6238 1
Trichomonas vaginalis calpain, putative 0.0215 0.0321 0.0834
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi Trypsin family protein 0.0066 0.0024 0.0032
Trypanosoma brucei cyclin 3 0.0058 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0223 0.0337 0.0535
Schistosoma mansoni neuropeptide receptor 0.0401 0.0695 0.0688
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0058 0.0008 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0879 0.1654 0.2046
Loa Loa (eye worm) cyclin domain-containing protein 0.0058 0.0008 0.0006
Trypanosoma brucei CHAP domain containing protein, putative 0.0066 0.0023 0.0128
Toxoplasma gondii kringle domain-containing protein 0.0133 0.0158 0.2253
Brugia malayi Peptidase family M13 containing protein 0.0294 0.0481 0.0765
Trichomonas vaginalis ubiquitin specific protease, putative 0.0062 0.0015 0.0027
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0187 0.0266 0.042
Mycobacterium ulcerans monoamine oxidase 0.0104 0.01 0.1668
Loa Loa (eye worm) hypothetical protein 0.0514 0.0922 0.1472
Toxoplasma gondii cathepsin B 0.01 0.0092 0.1282
Leishmania major hypothetical protein, conserved 0.0263 0.0419 0.2745
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0066 0.0024 0.0032
Plasmodium falciparum protoporphyrinogen oxidase 0.0104 0.01 0.1407
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Loa Loa (eye worm) proprotein convertase 2 0.0796 0.1487 0.2378
Loa Loa (eye worm) cyclin domain-containing protein 0.0058 0.0008 0.0006
Entamoeba histolytica hypothetical protein 0.0062 0.0014 0.0137
Mycobacterium ulcerans dehydrogenase 0.0104 0.01 0.1668
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0109 0.011 0.0136
Trypanosoma brucei subtilisin peptidase 0.0144 0.018 0.1161
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi PXA domain containing protein 0.0062 0.0014 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0767 0.143 0.9438
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0266 0.0423 0.2776
Brugia malayi regulator of G-protein signaling egl-10 0.0062 0.0014 0.0016
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0108 0.0107 0.0124
Trypanosoma brucei small myristoylated protein 1-1 0.041 0.0713 0.4695
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0062 0.0014 0.0018
Trypanosoma brucei Calpain-like protein CALP1.3 0.0478 0.0849 0.5595
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0177 0.0245 0.0386
Trichomonas vaginalis cyclins, putative 0.0422 0.0738 0.1931
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0153 0.0198 0.2643
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Mycobacterium tuberculosis Possible chitinase 0.0262 0.0416 0.8501
Trypanosoma brucei Calpain-like protein 1.1 0.081 0.1515 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0401 0.0695 0.0863
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0514 0.0922 0.1144
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.04 0.0692 0.4557
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Plasmodium falciparum sortilin 0.0207 0.0306 0.4451
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.002 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Leishmania major inhibitor of cysteine peptidase 0.023 0.0352 0.23
Toxoplasma gondii hypothetical protein 0.0058 0.0008 0.0039
Schistosoma mansoni neuropeptide receptor 0.0401 0.0695 0.0688
Schistosoma mansoni hypothetical protein 0.0066 0.0024 0.0016
Trichomonas vaginalis cyclins, putative 0.0422 0.0738 0.1931
Onchocerca volvulus 0.0133 0.0158 0.1422
Leishmania major cyclin 9, putative 0.0058 0.0008 0.0023
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus multilocularis calpain 5 0.0271 0.0435 0.054
Onchocerca volvulus 0.0401 0.0695 0.652
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0177 0.0245 0.1596
Plasmodium falciparum plasmepsin IX 0.0119 0.013 0.1846
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.0084 0.006 0.0074
Trypanosoma brucei Calpain-like protein 1.2 0.0619 0.1132 0.7465
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0144 0.018 0.0223
Loa Loa (eye worm) aminopeptidase N 0.0108 0.0107 0.0166
Echinococcus granulosus cathepsin L cysteine proteinase 0.0187 0.0266 0.0321
Plasmodium vivax vivapain-2 0.0187 0.0266 0.3831
Brugia malayi aspartic protease BmAsp-2, identical 0.0119 0.013 0.0202
Plasmodium vivax calpain, putative 0.029 0.0473 0.6892
Schistosoma mansoni cyclin B 0.0422 0.0738 0.0731
Loa Loa (eye worm) hypothetical protein 0.006 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Entamoeba histolytica GPI-anchor transamidase, putative 0.006 0.0011 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0129 0.015 0.0966
Trichomonas vaginalis hypothetical protein 0.0215 0.0321 0.0834
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0014 0.0024
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.006 0.0369
Loa Loa (eye worm) hypothetical protein 0.0223 0.0337 0.0535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0207 0.0306 0.1999
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.0084 0.006 0.0811
Echinococcus granulosus neuropeptides capa receptor 0.0401 0.0695 0.0855
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.0136 0.0876
Brugia malayi proprotein convertase 2 0.2012 0.3926 0.6292
Entamoeba histolytica cyclin, putative 0.0422 0.0738 1
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0058 0.0008 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0063 0.0018 0.0022
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus granulosus Regulator of G protein signaling 20 0.0062 0.0014 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0099 0.009 0.0568
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0456 0.0806 0.5307
Echinococcus granulosus somatostatin receptor 0.0401 0.0695 0.0855
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0401 0.0695 0.1109
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.04 0.0692 0.4557
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0486 0.0864 0.138
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0129 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0062 0.0014 0.0016
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0215 0.0321 0.0834
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.018 0.046
Brugia malayi PXA domain containing protein 0.0062 0.0014 0.0016
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0024 0.0016
Mycobacterium ulcerans chitinase/cellulase 0.0262 0.0416 0.8581
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0187 0.0266 0.0688
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.0084 0.006 0.0065
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0078 0.0047 0.059
Trypanosoma brucei calpain-like protein, putative 0.0528 0.0949 0.6259
Echinococcus multilocularis regulator of G protein signaling 3 0.0062 0.0014 0.0018
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0144 0.018 0.1161
Onchocerca volvulus Cathepsin L homolog 0.0187 0.0266 0.245
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0061 0.0012 0.0005
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0422 0.0738 0.4858
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0122 0.0136 0.1909
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Brugia malayi putative neuropeptide receptor NPR1 0.0401 0.0695 0.1109
Echinococcus multilocularis sex peptide receptor 0.0401 0.0695 0.0863
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0401 0.0695 0.0855
Loa Loa (eye worm) calpain family protein 1 0.0271 0.0435 0.0691
Schistosoma mansoni furin-1 (S08 family) 0.1361 0.2619 0.2614
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.003 0.0174
Echinococcus multilocularis cathepsin b 0.01 0.0092 0.0114
Schistosoma mansoni z-protein (S1r protein) 0.0062 0.0014 0.0007
Loa Loa (eye worm) hypothetical protein 0.0218 0.0327 0.0518
Toxoplasma gondii subtilisin SUB10 0.0144 0.018 0.2578
Onchocerca volvulus 0.0401 0.0695 0.652
Trichomonas vaginalis cyclins, putative 0.0058 0.0008 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0099 0.009 0.0082
Trichomonas vaginalis cyclin B, putative 0.0058 0.0008 0.0007
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.01 0.0092 0.0084
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0071 0.0034 0.0198
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0122 0.0136 0.016
Mycobacterium ulcerans chitinase/cellulase 0.0262 0.0416 0.8581
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.018 0.046
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Onchocerca volvulus 0.0146 0.0183 0.1665
Echinococcus multilocularis cyclin A3 4 0.0058 0.0008 0.0009
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.007 0.003 0.0042
Echinococcus multilocularis G1:S specific cyclin D1 0.0058 0.0008 0.0009
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0144 0.018 0.1161
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0014 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0081 0.0052 0.0125
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0796 0.1487 0.3906
Echinococcus granulosus cathepsin L cysteine protease 0.0099 0.009 0.0102
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0129 0.015 0.1989
Loa Loa (eye worm) hypothetical protein 0.0879 0.1654 0.2647
Brugia malayi Protein kinase domain containing protein 0.0133 0.0158 0.0246
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0228 0.0348 0.2278
Echinococcus granulosus endothelin converting enzyme 1 0.0294 0.0481 0.0588
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Chlamydia trachomatis protoporphyrinogen oxidase 0.0104 0.01 1
Giardia lamblia Cyclin A 0.0241 0.0375 0.1674
Trypanosoma cruzi trypanothione synthetase, putative 0.0066 0.0023 0.0128
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0109 0.011 0.017
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0058 0.0008 0.0023
Schistosoma mansoni amine GPCR 0.0401 0.0695 0.0688
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0357 0.0606 0.3986
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0192 0.0276 0.18
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0401 0.0695 0.0688
Toxoplasma gondii peptidase family M13 protein 0.0294 0.0481 0.703
Onchocerca volvulus 0.0187 0.0266 0.245
Trypanosoma brucei amidase, putative 0.0066 0.0023 0.0128
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.01 0.0092 0.0084
Loa Loa (eye worm) hypothetical protein 0.0514 0.0922 0.1472
Brugia malayi A-kinase anchor protein 10, precursor 0.0062 0.0014 0.0016
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.0081 0.0052 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Echinococcus granulosus axis inhibition protein axin 0.0062 0.0014 0.0008
Echinococcus multilocularis sortilin 0.0207 0.0306 0.038
Brugia malayi cathepsin L-like precursor 0.0127 0.0146 0.0228
Schistosoma mansoni serine-type protease inhibitor 0.3988 0.7889 0.7887
Loa Loa (eye worm) hypothetical protein 0.0066 0.0024 0.0032
Plasmodium falciparum cysteine proteinase falcipain 1 0.0099 0.009 0.1256
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.009 0.0138
Onchocerca volvulus 0.0187 0.0266 0.245
Echinococcus granulosus beta-adrenergic receptor kinase 0.0145 0.0181 0.0216
Brugia malayi calpain 7 0.0302 0.0497 0.0791
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.081 0.1515 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0024 0.0032
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0104 0.01 0.1373
Loa Loa (eye worm) zinc metallopeptidase 4 0.0072 0.0035 0.0049
Plasmodium falciparum cyclin 1 0.0058 0.0008 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0063 0.0018 0.0034
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0133 0.0158 0.2223
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0228 0.0348 0.2278
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0144 0.018 0.3403
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Loa Loa (eye worm) hypothetical protein 0.0266 0.0423 0.0673
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0024 0.0016
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0099 0.009 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Brugia malayi regulator of G-protein signaling rgs-7 0.0062 0.0014 0.0016
Onchocerca volvulus Neuropeptide F receptor homolog 0.0401 0.0695 0.652
Trypanosoma cruzi cysteine peptidase, putative 0.0326 0.0544 0.3577
Trypanosoma brucei calpain-like protein, putative 0.029 0.0473 0.3101
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0486 0.0864 0.1073
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Entamoeba histolytica hypothetical protein 0.0061 0.0012 0.0108
Plasmodium vivax plasmepsin V, putative 0.0119 0.013 0.1814
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0023 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0257 0.0406 0.2658
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0079 0.0048 0.0642
Brugia malayi Furin-like cysteine rich region family protein 0.0374 0.064 0.1021
Schistosoma mansoni hypothetical protein 0.006 0.0012 0.0004
Trypanosoma brucei Aminopeptidase M1, putative 0.0108 0.0107 0.0684
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0619 0.1132 0.7465
Loa Loa (eye worm) fibroinase 0.0187 0.0266 0.042
Brugia malayi endoprotease bli-4 precursor 0.3165 0.6238 1
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0215 0.0321 0.0834
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0122 0.0136 0.0169
Toxoplasma gondii cyclin dependent kinase binding protein 0.0058 0.0008 0.0039
Echinococcus multilocularis hypothetical protein 0.0271 0.0435 0.054
Plasmodium falciparum subtilisin-like protease 3 0.0144 0.018 0.2578
Trypanosoma brucei SUMO1/Ulp2, putative 0.0177 0.0245 0.1596
Giardia lamblia Cathepsin B precursor 0.01 0.0092 0.0384
Onchocerca volvulus 0.0187 0.0266 0.245
Echinococcus multilocularis sterol regulatory element binding protein 0.0109 0.011 0.0137
Echinococcus multilocularis neuropeptide Y receptor 0.0401 0.0695 0.0863
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.0043 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Trichomonas vaginalis cyclin B, putative 0.0058 0.0008 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0401 0.0695 0.0863
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0081 0.0052 0.0319
Onchocerca volvulus Putative endochitinase 0.0307 0.0507 0.4735
Trypanosoma cruzi mitotic cyclin, putative 0.0058 0.0008 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0018 0.009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0228 0.0348 0.2278
Leishmania major cathepsin L-like protease 0.0326 0.0544 0.3577
Schistosoma mansoni integrin alpha-ps 0.0276 0.0445 0.0438
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0021 0.0027
Trypanosoma brucei calpain-like protein, putative 0.029 0.0473 0.3101
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0125 0.0141 0.0606
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0215 0.0321 0.0834
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1097 0.7233
Echinococcus granulosus tachykinin peptides receptor 99D 0.0401 0.0695 0.0855
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0122 0.0136 0.0129
Trichomonas vaginalis calpain, putative 0.0215 0.0321 0.0834
Brugia malayi hypothetical protein 0.0119 0.013 0.0202
Trypanosoma cruzi cysteine peptidase, putative 0.0187 0.0266 0.1734
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0097 0.0085 0.0538
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Echinococcus multilocularis allatostatin A receptor 0.0401 0.0695 0.0863
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0271 0.0435 0.054
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0102 0.0095 0.0601
Echinococcus granulosus regulator of G protein signaling 3 0.0062 0.0014 0.0008
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0401 0.0695 0.652
Echinococcus multilocularis cathepsin L cysteine protease 0.0187 0.0266 0.033
Onchocerca volvulus 0.0144 0.018 0.163
Loa Loa (eye worm) cysteine protease 0.0187 0.0266 0.042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0401 0.0695 0.1109
Echinococcus multilocularis serotonin receptor 0.0401 0.0695 0.0863
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0018 0.015
Leishmania major trypanothione synthetase, putative 0.0066 0.0023 0.0128
Schistosoma mansoni neuropeptide receptor 0.0858 0.1611 0.1605
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0081 0.0052 0.0319
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.007 0.0031 0.018
Loa Loa (eye worm) hypothetical protein 0.0215 0.0321 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0008 0.0007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0061 0.0012 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Echinococcus multilocularis protein patched 0.0109 0.011 0.0137
Echinococcus multilocularis dro:myosuppressin receptor 0.0401 0.0695 0.0863
Plasmodium falciparum plasmepsin III 0.0119 0.013 0.1846
Onchocerca volvulus 0.0558 0.1009 0.9491
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0528 0.0949 0.6259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0146 0.0372
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0401 0.0695 0.0863
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0263 0.0419 0.2745
Schistosoma mansoni Mername-AA248 (C02 family) 0.0271 0.0435 0.0427
Brugia malayi Stress-activated protein kinase jnk-1 0.0486 0.0864 0.138
Loa Loa (eye worm) hypothetical protein 0.0584 0.1062 0.1698
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.029 0.0473 0.3101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0071 0.0034 0.0048
Echinococcus multilocularis neuropeptide receptor A26 0.0866 0.1627 0.202
Trypanosoma brucei calpain, putative 0.0215 0.0321 0.21
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.011 0.0136
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni hypothetical protein 0.0077 0.0045 0.0037
Trypanosoma cruzi ubiquitin hydrolase, putative 0.006 0.001 0.0041
Onchocerca volvulus 0.0518 0.0929 0.8737
Brugia malayi Regulator of G protein signaling domain containing protein 0.0062 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0215 0.0321 0.0509
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.007 0.0031 0.0039
Brugia malayi Cathepsin L-like precursor 0.0127 0.0146 0.0228
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0528 0.0949 0.6259
Brugia malayi Pepsin A precursor 0.0119 0.013 0.0202
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.009 0.1171
Schistosoma mansoni neuropeptide F-like receptor 0.0401 0.0695 0.0688
Leishmania major mitotic cyclin, putative 0.0058 0.0008 0.0023
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0071 0.0034 0.0042
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0266 0.0423 0.2776
Loa Loa (eye worm) hypothetical protein 0.0243 0.0379 0.0601
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0099 0.009 0.0082
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0144 0.018 0.0214
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0338 0.0569 0.3738
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0129 0.015 0.0966
Onchocerca volvulus 0.0066 0.0024 0.0156
Brugia malayi neuropeptide F receptor 0.0401 0.0695 0.1109
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0097 0.0085 0.0078
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0401 0.0695 0.0688
Echinococcus granulosus transmembrane protease serine 3 0.0066 0.0024 0.002
Trypanosoma cruzi major cysteine proteinase, putative 0.0178 0.0248 0.1616
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0063 0.0018 0.0022
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0115 0.0121 0.0188
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0144 0.018 0.3031
Plasmodium falciparum GPI-anchor transamidase, putative 0.006 0.0011 0.0089
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0558 0.101 0.6661
Loa Loa (eye worm) hypothetical protein 0.0294 0.0481 0.0765
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0401 0.0695 0.0863
Echinococcus granulosus calpain 5 0.0271 0.0435 0.0531
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.023 0.0352 0.4737
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0357 0.0606 0.3986
Echinococcus multilocularis g protein coupled receptor 0.0401 0.0695 0.0863
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.0419 0.2745
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0107 0.0133
Onchocerca volvulus Putative endochitinase 0.0307 0.0507 0.4735
Echinococcus multilocularis fmrfamide receptor 0.0401 0.0695 0.0863
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0401 0.0695 0.0688
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0081 0.0052 0.0125
Trichomonas vaginalis cyclin B, putative 0.0422 0.0738 0.1931
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0076 0.0043 0.0053
Brugia malayi Endochitinase 0.0307 0.0507 0.0807
Loa Loa (eye worm) cathepsin B 0.01 0.0092 0.0141
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0144 0.018 0.3031
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0021 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0111 0.0113 0.014
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0063 0.0018 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0263 0.0419 0.2745
Echinococcus multilocularis cysteine protease atg4b 0.0081 0.0052 0.0065
Loa Loa (eye worm) peptidase family M1 containing protein 0.0297 0.0486 0.0774
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.0132 0.0156 0.0244
Schistosoma mansoni hypothetical protein 0.0401 0.0695 0.0688
Trypanosoma cruzi cyclin 6, putative 0.0422 0.0738 0.4855
Plasmodium vivax aspartyl proteinase, putative 0.0119 0.013 0.1814
Loa Loa (eye worm) ctsf protein 0.0187 0.0266 0.042
Echinococcus multilocularis neuropeptides capa receptor 0.0401 0.0695 0.0863
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0245 0.0238
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0153 0.0198 0.1283
Leishmania major hypothetical protein, conserved 0.0263 0.0419 0.2745
Loa Loa (eye worm) hypothetical protein 0.0066 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.1948 0.3798 0.4715
Schistosoma mansoni hypothetical protein 0.0401 0.0695 0.0688
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.1948 0.3798 0.471
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0796 0.1487 0.3906
Echinococcus multilocularis calpain 7 (C02 family) 0.0302 0.0497 0.0617
Trypanosoma cruzi mitotic cyclin, putative 0.0058 0.0008 0.0023
Plasmodium falciparum plasmepsin VII 0.0119 0.013 0.1846
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0074 0.0039 0.0039
Echinococcus multilocularis fmrfamide receptor 0.0401 0.0695 0.0863
Plasmodium falciparum cysteine repeat modular protein 1 0.0133 0.0158 0.2253
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0149 0.0189 0.0181
Echinococcus multilocularis somatostatin receptor 0.0401 0.0695 0.0863
Loa Loa (eye worm) calpain D 0.0282 0.0457 0.0726
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0558 0.101 0.6661
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0111 0.0113 0.0131
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0071 0.0034 0.0033
Echinococcus multilocularis calpain 0.0271 0.0435 0.054
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0066 0.0024 0.002
Echinococcus multilocularis expressed protein 0.0791 0.1478 0.1835
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0076 0.0044 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.018 0.046
Echinococcus granulosus rhodopsin orphan GPCR 0.0401 0.0695 0.0855
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0108 0.0107 0.027
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0076 0.0044 0.0545
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.0044 0.0064
Mycobacterium leprae probable zinc metalloprotease 0.0294 0.0481 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Schistosoma mansoni neprilysin-2 (M13 family) 0.0149 0.0189 0.0181
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0062 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0039 0.0233
Onchocerca volvulus 0.0066 0.0024 0.0156
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0391 0.0675 0.4443
Brugia malayi ubiquitin specific protease 14 0.007 0.003 0.0042
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1948 0.3798 1
Loa Loa (eye worm) hypothetical protein 0.3165 0.6238 1
Echinococcus granulosus neuropeptide receptor A26 0.0866 0.1627 0.2012
Onchocerca volvulus 0.0401 0.0695 0.652
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0122 0.0136 0.0129
Echinococcus granulosus cysteine protease atg4b 0.0081 0.0052 0.0056
Echinococcus granulosus regulator of G protein signaling 7 0.0062 0.0014 0.0008
Brugia malayi Dopamine receptor protein 1 0.0401 0.0695 0.1109
Echinococcus granulosus Mastin 0.0066 0.0024 0.002
Schistosoma mansoni integrin beta subunit 0.0931 0.1758 0.1752
Schistosoma mansoni hypothetical protein 0.0401 0.0695 0.0688
Schistosoma mansoni hypothetical protein 0.0066 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.0084 0.006 0.0089
Echinococcus granulosus dnaJ subfamily B 0.2405 0.4714 0.5848
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.029 0.0473 0.3101
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0192 0.0276 0.18
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.0375 0.0975
Toxoplasma gondii aspartyl protease ASP3 0.0119 0.013 0.1846
Trypanosoma brucei small myristoylated protein 1-2 0.041 0.0713 0.4695
Echinococcus multilocularis g-protein coupled receptor 0.0401 0.0695 0.0863
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Onchocerca volvulus 0.0401 0.0695 0.652
Leishmania major calpain family cysteine protease-like protein 0.0545 0.0985 0.6491
Echinococcus granulosus cathepsin l1 0.0127 0.0146 0.0172
Echinococcus granulosus calpain 7 C02 family 0.0302 0.0497 0.0608
Echinococcus granulosus g-protein coupled receptor 0.0401 0.0695 0.0855
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0043 0.01
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0796 0.1487 0.3906
Plasmodium vivax vivapain-1 0.0099 0.009 0.1222
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0079 0.0048 0.006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0401 0.0695 0.0855
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0395 0.0682 0.4488
Toxoplasma gondii subtilisin SUB12 0.0186 0.0263 0.3812
Echinococcus granulosus glutamate NMDA receptor subunit 0.0259 0.0409 0.0499
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0061 0.0012 0.0015
Toxoplasma gondii subtilisin SUB4 0.0144 0.018 0.2578
Echinococcus granulosus integrin beta 2 0.1174 0.2246 0.2781
Echinococcus multilocularis beta adrenergic receptor kinase 0.0145 0.0181 0.0225
Schistosoma mansoni hypothetical protein 0.0077 0.0045 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.04 0.0692 0.4557
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0109 0.011 0.0103
Echinococcus granulosus lysine specific histone demethylase 1A 0.0514 0.0922 0.1136
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.006 0.0369
Echinococcus multilocularis integrin beta 2 0.1174 0.2246 0.2788
Brugia malayi hypothetical protein 0.0104 0.01 0.0154
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0044 0.0103
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0076 0.0043 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0328 0.0549 0.1434
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.0419 0.2745
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0018 0.009
Echinococcus multilocularis cathepsin b 0.01 0.0092 0.0114
Trichomonas vaginalis cyclin B3, putative 0.0241 0.0375 0.0975
Toxoplasma gondii subtilisin SUB8 0.0144 0.018 0.2578
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0079 0.0048 0.0293
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0796 0.1487 0.3906
Brugia malayi calpain family protein 1 0.0271 0.0435 0.0691
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0044 0.0265
Trichomonas vaginalis hypothetical protein 0.0652 0.1198 0.3145
Schistosoma mansoni cathepsin F (C01 family) 0.0187 0.0266 0.0259
Trypanosoma brucei mitotic cyclin 6 0.0422 0.0738 0.4855
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0153 0.0198 0.1283
Loa Loa (eye worm) chitinase I 0.0307 0.0507 0.0807
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.006 0.0011 0.0016
Mycobacterium ulcerans aminopeptidase N PepN 0.0108 0.0107 0.1826
Loa Loa (eye worm) hypothetical protein 0.0223 0.0337 0.0535
Echinococcus granulosus g protein coupled receptor 0.0401 0.0695 0.0855
Brugia malayi G-protein coupled receptor 0.0401 0.0695 0.1109
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0079 0.0048 0.5
Entamoeba histolytica cysteine proteinase 2 0.0099 0.009 0.1171
Loa Loa (eye worm) hypothetical protein 0.0466 0.0825 0.1318
Leishmania major hypothetical protein, conserved 0.0263 0.0419 0.2745
Loa Loa (eye worm) melatonin receptor type 1A 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.0136 0.0347
Brugia malayi Dopamine receptor 0.0401 0.0695 0.1109
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.3165 0.6238 0.6235
Loa Loa (eye worm) hypothetical protein 0.0127 0.0146 0.0228
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0228 0.0348 0.2278
Echinococcus multilocularis protein dispatched 1 0.0109 0.011 0.0137
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.002 0.0039
Trichomonas vaginalis cyclin B, putative 0.0241 0.0375 0.0975
Echinococcus multilocularis 0.2513 0.4931 0.6121
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0044 0.0265
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.0136 0.0347
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) cyclin domain-containing protein 0.0241 0.0375 0.0595
Loa Loa (eye worm) hypothetical protein 0.0066 0.0024 0.0032
Mycobacterium ulcerans zinc metalloprotease 0.0294 0.0481 1
Onchocerca volvulus 0.0367 0.0627 0.5872
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0104 0.01 0.1407
Trypanosoma brucei RNA helicase, putative 0.0214 0.032 0.209
Brugia malayi Cyclin, N-terminal domain containing protein 0.0058 0.0008 0.0006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0587 0.1069 0.7047
Echinococcus multilocularis membrane bound transcription factor site 1 0.0144 0.018 0.0223
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0207 0.0306 0.1999
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0386 0.0665 0.9746
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0401 0.0695 0.0863
Brugia malayi hypothetical protein 0.0243 0.0379 0.0601
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0144 0.018 0.1161
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.007 0.003 0.0376
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0062 0.0014 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Giardia lamblia High cysteine membrane protein Group 2 0.1153 0.2202 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0401 0.0695 0.1109
Echinococcus granulosus cathepsin L 0.0099 0.009 0.0102
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.006 0.0011 0.0045
Echinococcus multilocularis regulator of G protein signaling 7 0.0062 0.0014 0.0018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0338 0.0569 0.3738
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0102 0.0095 0.0601
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0111 0.0113 0.0719
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0401 0.0695 0.0863
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.002 0.0039
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0122 0.0136 0.194
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0254 0.0401 0.2625
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0021 0.0013
Trypanosoma cruzi trypanothione synthetase 0.0066 0.0023 0.0128
Leishmania major UDP-galactopyranose mutase 0.0104 0.01 0.0636
Brugia malayi RE15519p 0.0401 0.0695 0.1109
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.007 0.003 0.0038
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0097 0.0085 0.0106
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0187 0.0266 0.3855
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Schistosoma mansoni hypothetical protein 0.0214 0.032 0.0312
Plasmodium vivax unspecified product 0.0099 0.009 0.1222
Onchocerca volvulus Putative endochitinase 0.0307 0.0507 0.4735
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0063 0.0018 0.001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0528 0.0949 0.6259
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0102 0.0095 0.0601
Brugia malayi Cathepsin L-like precursor 0.0187 0.0266 0.042
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0108 0.0107 0.0133
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0097 0.0085 0.013
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.006 0.0369
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0044 0.0055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0357 0.0606 0.3986
Echinococcus multilocularis cyclin k 0.0058 0.0008 0.0009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0879 0.1654 0.2647
Loa Loa (eye worm) hypothetical protein 0.0062 0.0014 0.0016
Trichomonas vaginalis calpain, putative 0.0215 0.0321 0.0834
Schistosoma mansoni hypothetical protein 0.0077 0.0045 0.0037
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0528 0.0949 0.6259
Trypanosoma cruzi cruzipain precursor, putative 0.0326 0.0544 0.3577
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0144 0.018 0.3031
Schistosoma mansoni adenoreceptor 0.0401 0.0695 0.0688
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0478 0.0849 0.5595
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0076 0.0043 0.0161
Loa Loa (eye worm) hypothetical protein 0.0062 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0395 0.0682 0.1088
Echinococcus multilocularis aminopeptidase N 0.0367 0.0627 0.0778
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Trypanosoma brucei unspecified product 0.0263 0.0419 0.2745
Brugia malayi larval opioid receptor 0.0401 0.0695 0.1109
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0076 0.0044 0.0167
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.009 0.0138
Echinococcus granulosus enteropeptidase 0.0066 0.0024 0.002
Leishmania major hypothetical protein, conserved 0.0263 0.0419 0.2745
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni patched 1 0.0109 0.011 0.0103
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0058 0.0008 0.0039
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0122 0.0136 0.194
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.007 0.003 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0257 0.0406 0.2658
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0228 0.0348 0.2278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Loa Loa (eye worm) hypothetical protein 0.0148 0.0187 0.0294
Leishmania major subtilisin-like serine peptidase 0.0144 0.018 0.1161
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0115 0.0121 0.0142
Echinococcus multilocularis cyclin B3 1 0.0241 0.0375 0.0465
Echinococcus granulosus cathepsin b 0.01 0.0092 0.0105
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Brugia malayi hypothetical protein 0.0119 0.013 0.0202
Schistosoma mansoni hypothetical protein 0.0401 0.0695 0.0688
Onchocerca volvulus Cathepsin F homolog 0.0187 0.0266 0.245
Brugia malayi hypothetical protein 0.0058 0.0008 0.0006
Plasmodium vivax aspartyl protease, putative 0.0119 0.013 0.1814
Loa Loa (eye worm) hypothetical protein 0.0262 0.0416 0.0661
Entamoeba histolytica calpain family cysteine protease, putative 0.0282 0.0457 0.6169
Plasmodium falciparum plasmepsin IV 0.0395 0.0682 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0327 0.0518
Loa Loa (eye worm) hypothetical protein 0.0422 0.0738 0.1177
Schistosoma mansoni integrin alpha-ps 0.0144 0.0179 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.01 0.0092 0.0229
Loa Loa (eye worm) hypothetical protein 0.0058 0.0008 0.0006
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Trichomonas vaginalis cyclins, putative 0.0058 0.0008 0.0007
Toxoplasma gondii subtilisin SUB2 0.0144 0.018 0.2578
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.007 0.003 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Leishmania major cathepsin L-like protease 0.0187 0.0266 0.1734
Entamoeba histolytica protein kinase, putative 0.0058 0.0008 0.0047
Schistosoma mansoni hypothetical protein 0.0652 0.1198 0.1191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0144 0.018 0.3031
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0108 0.0107 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0181 0.0174
Leishmania major cathepsin L-like protease 0.0326 0.0544 0.3577
Schistosoma mansoni hypothetical protein 0.0077 0.0045 0.0037
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0259 0.0409 0.0508
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0395 0.0682 0.1786
Giardia lamblia Cathepsin B precursor 0.01 0.0092 0.0384
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0113 0.0719
Echinococcus multilocularis orexin receptor type 2 0.0401 0.0695 0.0863
Loa Loa (eye worm) trypsin family protein 0.0066 0.0024 0.0032
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0271 0.0435 0.0427
Schistosoma mansoni calpain-2 (C02 family) 0.0215 0.0321 0.0314
Entamoeba histolytica cysteine protease, putative 0.0099 0.009 0.1171
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0259 0.041 0.2686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1948 0.3798 1
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.018 0.046
Brugia malayi hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni axis inhibition protein axin 0.0062 0.0014 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Echinococcus multilocularis epidermal growth factor receptor 0.0374 0.064 0.0795
Echinococcus multilocularis cathepsin L cysteine protease 0.0187 0.0266 0.033
Leishmania major PFPI/DJ-1-like protein, putative 0.0443 0.078 0.5136
Loa Loa (eye worm) hypothetical protein 0.0127 0.0146 0.0228
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0271 0.0435 0.0531
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0228 0.0348 0.2278
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0024 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.003 0.0174
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0119 0.013 0.0202
Trypanosoma cruzi unspecified product 0.041 0.0713 0.4695
Brugia malayi sulfakinin receptor protein 0.0401 0.0695 0.1109
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0266 0.0423 0.0416
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Schistosoma mansoni biogenic amine (5HT) receptor 0.0401 0.0695 0.0688
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.009 0.0224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0044 0.0103
Echinococcus multilocularis integrin alpha 3 0.0472 0.0838 0.104
Leishmania major mitotic cyclin, putative 0.0058 0.0008 0.0023
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0071 0.0034 0.0198
Echinococcus multilocularis transmembrane protease serine 3 0.0066 0.0024 0.003
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0263 0.0419 0.2745
Entamoeba histolytica cyclin, domain containing protein 0.0058 0.0008 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0187 0.0266 0.0688
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Leishmania major hypothetical protein, conserved 0.0263 0.0419 0.2745
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0102 0.0095 0.0146
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0129 0.015 0.0382
Loa Loa (eye worm) hypothetical protein 0.0218 0.0327 0.0518
Schistosoma mansoni alpha-1 adrenergic receptor 0.0401 0.0695 0.0688
Mycobacterium ulcerans epoxide hydrolase EphA 0.0168 0.0227 0.4442
Loa Loa (eye worm) hypothetical protein 0.0189 0.027 0.0426
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Onchocerca volvulus Putative endochitinase 0.0307 0.0507 0.4735
Echinococcus granulosus cathepsin b 0.01 0.0092 0.0105
Plasmodium vivax vivapain-2 0.0187 0.0266 0.3831
Leishmania major chitinase 0.0307 0.0507 0.333
Echinococcus granulosus cyclin B 0.0422 0.0738 0.0907
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0144 0.018 0.1161
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0081 0.0052 0.0319
Schistosoma mansoni cathepsin s 0.006 0.0011 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0097 0.0085 0.013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0401 0.0695 0.0863
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Schistosoma mansoni autophagin-1 (C54 family) 0.0081 0.0052 0.0045
Echinococcus multilocularis ubiquitin specific protease 41 0.0076 0.0044 0.0055
Toxoplasma gondii cathepsin CPL 0.0187 0.0266 0.3855
Loa Loa (eye worm) hypothetical protein 0.0127 0.0146 0.0228
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0187 0.0266 0.042
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Schistosoma mansoni regulator of G protein signaling 0.0062 0.0014 0.0007
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0401 0.0695 0.0688
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.006 0.0011 0.0045
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0021 0.0111
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0294 0.0481 1
Onchocerca volvulus 0.0187 0.0266 0.245
Plasmodium falciparum cysteine proteinase falcipain 3 0.0187 0.0266 0.3855
Plasmodium falciparum plasmepsin VIII, putative 0.0119 0.013 0.1846
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.081 0.1515 1
Schistosoma mansoni biogenic amine receptor 0.0401 0.0695 0.0688
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0008 0.0023
Loa Loa (eye worm) cyclin domain-containing protein 0.0058 0.0008 0.0006
Loa Loa (eye worm) aspartyl protease 6 0.0119 0.013 0.0202
Onchocerca volvulus Cathepsin L homolog 0.0187 0.0266 0.245
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0063 0.0018 0.0188
Trichomonas vaginalis cyclins, putative 0.0239 0.037 0.0963
Onchocerca volvulus 0.0066 0.0024 0.0156
Brugia malayi Cyclin, N-terminal domain containing protein 0.0422 0.0738 0.1177
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0326 0.0544 0.3577
Plasmodium falciparum plasmepsin V 0.0119 0.013 0.1846
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0401 0.0695 0.0688
Giardia lamblia Hypothetical protein 0.0241 0.0375 0.1674
Plasmodium vivax GPI-anchor transamidase, putative 0.006 0.0011 0.005
Brugia malayi hypothetical protein 0.0058 0.0008 0.0006
Echinococcus multilocularis cysteine protease 0.0187 0.0266 0.033
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0266 0.0423 0.2776
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0552 0.0997 0.6573
Echinococcus granulosus cysteine protease 0.0099 0.009 0.0102
Loa Loa (eye worm) hypothetical protein 0.0223 0.0337 0.0535
Plasmodium falciparum subtilisin-like protease 2 0.0144 0.018 0.2578
Loa Loa (eye worm) hypothetical protein 0.0062 0.0014 0.0016
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0076 0.0044 0.0037
Trichomonas vaginalis cyclin B, putative 0.0422 0.0738 0.1931
Schistosoma mansoni amine GPCR 0.0401 0.0695 0.0688
Echinococcus multilocularis cyclin t1 0.0058 0.0008 0.0009
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0108 0.0107 0.0684
Schistosoma mansoni opsin-like receptor 0.0401 0.0695 0.0688
Echinococcus multilocularis axis inhibition protein axin 0.0062 0.0014 0.0018
Brugia malayi Integrin beta pat-3 precursor 0.1589 0.3078 0.4932
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0767 0.143 0.9438
Trypanosoma brucei mitotic cyclin 0.0058 0.0008 0.0023
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0018 0.009
Plasmodium vivax hypothetical protein, conserved 0.0104 0.01 0.1373
Echinococcus granulosus calpain A 0.0271 0.0435 0.0531
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0144 0.018 0.046
Echinococcus granulosus integrin alpha ps 0.0132 0.0156 0.0185
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0044 0.0045
Toxoplasma gondii peptidase c13 family protein 0.006 0.0011 0.0089
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0115 0.0121 0.0188
Loa Loa (eye worm) hypothetical protein 0.0401 0.0695 0.1109
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus granulosus c-Jun N-terminal kinases 0.0486 0.0864 0.1065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0796 0.1487 0.3906
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0063 0.0018 0.0034
Echinococcus multilocularis calpain A 0.0271 0.0435 0.054
Echinococcus granulosus biogenic amine 5HT receptor 0.0401 0.0695 0.0855
Onchocerca volvulus 0.0401 0.0695 0.652
Loa Loa (eye worm) hypothetical protein 0.0066 0.0024 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0266 0.0688
Brugia malayi calpain family protein 1 0.0271 0.0435 0.0691
Schistosoma mansoni integrin alpha 0.0616 0.1127 0.112
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0254 0.0401 0.2625
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0076 0.0043 0.0044
Echinococcus granulosus furin 0.3165 0.6238 0.7742
Loa Loa (eye worm) peptidase family M13 containing protein 0.0218 0.0327 0.0518
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0021 0.0017
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0081 0.0052 0.0045
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0104 0.01 0.1407
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0071 0.0034 0.0048
Loa Loa (eye worm) cyclin domain-containing protein 0.0058 0.0008 0.0006
Plasmodium vivax vivapain-3 0.0099 0.009 0.1222
Echinococcus multilocularis cyclin b3 0.0241 0.0375 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.0419 0.2745
Entamoeba histolytica cyclin, putative 0.0241 0.0375 0.5055
Loa Loa (eye worm) hypothetical protein 0.0058 0.0008 0.0006
Brugia malayi Subtilase family protein 0.0144 0.018 0.0281
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.006 0.0011 0.0016
Leishmania major cathepsin L-like protease 0.0187 0.0266 0.1734
Brugia malayi Cathepsin L-like precursor 0.0187 0.0266 0.042
Schistosoma mansoni hypothetical protein 0.0133 0.0158 0.015
Schistosoma mansoni growth hormone secretagogue receptor 0.0401 0.0695 0.0688
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0115 0.0121 0.0151
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Schistosoma mansoni calpain (C02 family) 0.0271 0.0435 0.0427
Echinococcus granulosus g protein coupled receptor 0.0401 0.0695 0.0855
Loa Loa (eye worm) hypothetical protein 0.0122 0.0136 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0187 0.0266 0.0688
Toxoplasma gondii exonuclease 0.006 0.001 0.008
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0558 0.101 0.6661
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.081 0.1515 1
Brugia malayi amine oxidase, flavin-containing family protein 0.0148 0.0187 0.0294
Onchocerca volvulus 0.0401 0.0695 0.652
Echinococcus multilocularis 0.0104 0.01 0.0124
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0466 0.0825 0.1318
Echinococcus granulosus Protein patched homolog 1 0.0109 0.011 0.0127
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0024 0.003
Leishmania major cathepsin L-like protease 0.0187 0.0266 0.1734
Schistosoma mansoni tyrosine kinase 0.0374 0.064 0.0633
Echinococcus multilocularis endothelin converting enzyme 1 0.0294 0.0481 0.0597
Loa Loa (eye worm) hypothetical protein 0.0223 0.0337 0.0535
Loa Loa (eye worm) hypothetical protein 0.0422 0.0738 0.1177
Loa Loa (eye worm) hypothetical protein 0.0187 0.0266 0.042
Loa Loa (eye worm) hypothetical protein 0.007 0.0031 0.0044
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0307 0.0506 0.3322
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0021 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0652 0.1198 0.3145
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0228 0.0348 0.2278
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0153 0.0198 0.1283
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0401 0.0695 0.0688
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0177 0.0245 0.1596
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0014 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0119 0.013 0.0123
Trypanosoma brucei calpain, putative 0.0471 0.0836 0.5508
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.006 0.0011 0.0045
Schistosoma mansoni regulator of G protein signaling 0.0062 0.0014 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0401 0.0695 0.0863
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0063 0.0018 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.04 0.0692 0.4557
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0076 0.0043 0.0561
Brugia malayi G-protein coupled receptor 0.0401 0.0695 0.1109
Onchocerca volvulus 0.0187 0.0266 0.245
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0401 0.0695 0.1109
Echinococcus multilocularis cyclin y 0.0058 0.0008 0.0009
Echinococcus multilocularis tissue type plasminogen activator 0.0133 0.0158 0.0196
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.081 0.1515 1
Echinococcus multilocularis G protein coupled receptor 139 0.0858 0.1611 0.2
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.4071 0.8055 1
Trypanosoma cruzi subtilisin peptidase 0.0144 0.018 0.1161
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0401 0.0695 0.0688
Brugia malayi Cathepsin L-like precursor 0.0127 0.0146 0.0228
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0207 0.0306 0.1999
Echinococcus multilocularis cyclin B 0.0422 0.0738 0.0916
Leishmania major trypanothione synthetase-like protein 0.0066 0.0023 0.0128
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0066 0.0023 0.0128
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0066 0.0023 0.0128
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.0136 0.0876
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0144 0.018 0.0281
Schistosoma mansoni neprilysin 0.0077 0.0045 0.0037
Echinococcus granulosus neuropeptide Y receptor 0.0401 0.0695 0.0855
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0014 0.0024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0129 0.015 0.0966
Schistosoma mansoni calpain-7 (C02 family) 0.0345 0.0583 0.0576
Echinococcus granulosus cyclins 0.0241 0.0375 0.0456
Entamoeba histolytica cyclin family protein 0.0241 0.0375 0.5055
Echinococcus multilocularis cyclins 0.0241 0.0375 0.0465
Brugia malayi Trypsin family protein 0.0584 0.1062 0.1698
Brugia malayi Peptidase family M1 containing protein 0.0367 0.0627 0.0999
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0215 0.0321 0.0834

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.25 ug ml-1 Minimal inhibitory concentration against methicillin susceptible Staphylococcus aureus giorgio ChEMBL. 10999485
MIC (functional) = 0.25 ug ml-1 Minimal inhibitory concentration against Haemophilus influenza HIN003, beta lactamase producing resistant strain ChEMBL. 10999485
MIC (functional) = 0.5 ug ml-1 Minimal inhibitory concentration against Proteus vulgaris 6059 ChEMBL. 10999485
MIC (functional) = 0.5 ug ml-1 Minimal inhibitory concentration against Moraxella catarrhalis 25240 ChEMBL. 10999485
MIC (functional) = 1 ug ml-1 Minimal inhibitory concentration against Escherichia coli 3190Y ChEMBL. 10999485
MIC (functional) = 1 ug ml-1 Minimal inhibitory concentration against Streptococcus pneumonia PN010, penicillin resistant ChEMBL. 10999485
MIC (functional) = 1 ug ml-1 Minimal inhibitory concentration against Escherichia coli 3190Y ChEMBL. 10999485
MIC (functional) = 2 ug ml-1 Minimal inhibitory concentration against methicillin resistant Staphylococcus aureus 77 ChEMBL. 10999485
MIC (functional) = 2 ug ml-1 Minimal inhibitory concentration against Enterococcus faecalis 29212 ChEMBL. 10999485
MIC (functional) = 8 ug ml-1 Minimal inhibitory concentration against Klebsiella pneumonia 2011E ChEMBL. 10999485

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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