Detailed information for compound 1077122

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 577.638 | Formula: C34H27N9O
  • H donors: 4 H acceptors: 5 LogP: 7.71 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#Cc1c(N)nc(cc1c1ccccc1OC)c1ccc(cc1)Nc1nc(Nc2ccccc2)nc(n1)Nc1ccccc1
  • InChi: 1S/C34H27N9O/c1-44-30-15-9-8-14-26(30)27-20-29(40-31(36)28(27)21-35)22-16-18-25(19-17-22)39-34-42-32(37-23-10-4-2-5-11-23)41-33(43-34)38-24-12-6-3-7-13-24/h2-20H,1H3,(H2,36,40)(H3,37,38,39,41,42,43)
  • InChiKey: BIQPPACOXIKXOX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Alanyl dipeptidyl peptidase 0.0009 0.0034 0.003
Schistosoma mansoni terminal deoxycytidyl transferase 0.0032 0.0224 0.0265
Trichomonas vaginalis D-aminoacylase, putative 0.0098 0.077 0.2702
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0032 0.0224 0.0217
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0092 0.0317
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0022 0.0059
Brugia malayi Hhat protein 0.0011 0.0049 0.0145
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0124 0.1587
Echinococcus multilocularis geminin 0.1016 0.8364 0.8363
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Brugia malayi Flap endonuclease-1 0.0018 0.0103 0.0311
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0052 0.0045
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0129 0.0243
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0042 0.0306 0.0357
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0009 0.0028 0.003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0015 0.008 0.1038
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0138 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0129 0.1676
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0537 0.5745
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0011 0.0049 0.0051
Leishmania major oligopeptidase b 0.0009 0.0034 0.0442
Toxoplasma gondii serine/threonine phosophatase PP1 0.0009 0.0029 0.0243
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0326 0.0319
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0569 0.7385
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0014 0.0071 0.0835
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0022 0.0023
Loa Loa (eye worm) acyl carrier protein 0.0008 0.0023 0.0063
Mycobacterium ulcerans hypothetical protein 0.0118 0.093 0.1764
Loa Loa (eye worm) hypothetical protein 0.0028 0.0184 0.0563
Mycobacterium ulcerans lipase LipD 0.0098 0.077 0.146
Echinococcus multilocularis expressed protein 0.0009 0.0028 0.0021
Brugia malayi ecdysteroid receptor 0.0008 0.0022 0.0059
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0014 0.0071 0.0064
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0033 0.0231 0.0709
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0016 0.0085 0.5
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0018 0.0101 0.0191
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0008 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.0145
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.0058
Loa Loa (eye worm) flap endonuclease-1 0.0018 0.0103 0.0311
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0129 0.1676
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0061 0.0182
Onchocerca volvulus Fatty acid synthase homolog 0.0032 0.0218 0.0654
Trypanosoma brucei glycerol uptake protein, putative 0.0011 0.0049 0.061
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0119 0.0938 0.1114
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0009 0.0028 0.0079
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0018 0.0101 0.0189
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0268 0.2172 0.6723
Echinococcus granulosus sterol O acyltransferase 1 0.0115 0.0909 0.1079
Mycobacterium ulcerans polyketide synthase Pks13 0.0026 0.0173 0.0327
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Brugia malayi latrophilin 2 splice variant baaae 0.0183 0.1471 0.4551
Onchocerca volvulus 0.0008 0.0022 0.0046
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0011 0.0049 0.0293
Trichomonas vaginalis protein phosphatase-5, putative 0.0012 0.0054 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0039 0.0511
Schistosoma mansoni Smad4 0.0008 0.0024 0.0026
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0199 0.1601 1
Onchocerca volvulus 0.0023 0.0142 0.0421
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0008 0.0022 0.0018
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0028 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0008 0.0022 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0036 0.025 0.0296
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0101 0.0191
Plasmodium falciparum peptidase, putative 0.0009 0.0034 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0049 0.0165
Loa Loa (eye worm) nuclear factor I 0.001 0.0041 0.0118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Toxoplasma gondii serine/threonine protein phosphatase 0.002 0.0118 0.1203
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0024 0.0068
Schistosoma mansoni ran 0.0015 0.008 0.0093
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0022 0.0023
Brugia malayi mothers against decapentaplegic homolog 3 0.0008 0.0024 0.0068
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0007 0.0015 0.0027
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0018 0.0103 0.1335
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0006 0.0007 0.0012
Echinococcus multilocularis ETS transcription factor Elf 1 0.0012 0.0052 0.0045
Treponema pallidum licC protein (licC) 0.0118 0.093 0.5678
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Brugia malayi MH2 domain containing protein 0.0008 0.0024 0.0068
Trypanosoma cruzi oligopeptidase b 0.0009 0.0034 0.0442
Schistosoma mansoni transcription factor LCR-F1 0.0084 0.0652 0.0777
Mycobacterium ulcerans bacterioferritin BfrA 0.0011 0.005 0.0092
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.1623 0.1939
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0144 0.0883
Trichomonas vaginalis esterase, putative 0.0098 0.077 0.2702
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0028 0.0184 0.0217
Trichomonas vaginalis antibiotic synthetase, putative 0.0006 0.0007 0.0016
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0025 0.0161 0.1669
Leishmania major importin beta-1 subunit, putative 0.0016 0.0092 0.1201
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.0009 0.0029 0.0399
Onchocerca volvulus 0.0395 0.3229 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0098 0.077 0.146
Entamoeba histolytica hypothetical protein, conserved 0.0011 0.0049 0.0293
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.093 0.1764
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0062 0.0468 0.6084
Loa Loa (eye worm) hhat protein 0.0011 0.0049 0.0145
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0022 0.0023
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0109 0.0122
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Toxoplasma gondii hypothetical protein 0.0011 0.0049 0.0459
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Brugia malayi hypothetical protein 0.0074 0.0569 0.1756
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0019 0.011 0.0208
Mycobacterium ulcerans DNA polymerase IV 0.0032 0.0224 0.0424
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0006 0.0002 0.0002
Loa Loa (eye worm) T-complex protein 1 0.0014 0.0071 0.0211
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Brugia malayi hypothetical protein 0.0185 0.1489 0.4608
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0569 0.6088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0016 0.0085 0.016
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0037 0.0261 0.0309
Brugia malayi nuclear hormone receptor 0.0008 0.0022 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Giardia lamblia Fructose-bisphosphate aldolase 0.0199 0.1601 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0098 0.077 0.0763
Echinococcus granulosus protein C ets 2 0.0012 0.0052 0.0054
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Schistosoma mansoni hypothetical protein 0.0012 0.0052 0.0059
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0138 0.0261
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0011 0.0049 0.0042
Mycobacterium tuberculosis Probable esterase LipL 0.0098 0.077 0.146
Entamoeba histolytica hypothetical protein 0.0011 0.0049 0.0293
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Plasmodium falciparum T-complex protein 1 subunit beta 0.0014 0.0071 0.1133
Schistosoma mansoni hypothetical protein 0.0084 0.0652 0.0777
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0052 0.0054
Schistosoma mansoni ets 0.0012 0.0052 0.0059
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0014 0.0073 0.0137
Mycobacterium ulcerans esterase/lipase LipP 0.0098 0.077 0.146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Echinococcus granulosus mothers against decapentaplegic 2 0.0008 0.0024 0.0021
Schistosoma mansoni hypothetical protein 0.0217 0.175 0.209
Schistosoma mansoni Smad4 0.0008 0.0024 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0008 0.0022 0.0059
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0011 0.0049 0.0051
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0011 0.0049 0.0056
Echinococcus multilocularis microtubule associated protein 2 0.055 0.4509 0.4505
Brugia malayi hypothetical protein 0.0048 0.0352 0.1083
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.0029 0.0095
Brugia malayi Smad1 0.0018 0.0109 0.0329
Trypanosoma brucei hypothetical protein, conserved 0.0098 0.077 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Trypanosoma cruzi serine/threonine protein phosphatase type 5, putative 0.0021 0.0127 0.1645
Mycobacterium ulcerans bacterioferritin BfrB 0.0011 0.005 0.0092
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0011 0.005 0.047
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0008 0.0022 0.0059
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.0009 0.0029 0.0381
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0008 0.0022 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Schistosoma mansoni ferritin light chain 0.0011 0.005 0.0056
Mycobacterium tuberculosis Probable hydrolase 0.0098 0.077 0.146
Entamoeba histolytica hypothetical protein, conserved 0.0009 0.0034 0.0197
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0569 1
Mycobacterium ulcerans hypothetical protein 0.0118 0.093 0.1764
Mycobacterium leprae Probable polyketide synthase Pks1 0.0019 0.011 0.0206
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0011 0.0049 0.0042
Trichomonas vaginalis importin beta-1, putative 0.0016 0.0092 0.0317
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0009 0.0034 0.0038
Echinococcus granulosus ETS transcription factor Elf 5 0.0012 0.0052 0.0054
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0011 0.0049 0.0056
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.024 0.0284
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0138 0.0478
Echinococcus granulosus GTP binding nuclear protein Ran 0.0015 0.008 0.0087
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0009 0.0029 0.0095
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.0028 0.0025
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0119 0.0938 0.0932
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0024 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0008 0.0022 0.0059
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0032 0.0224 0.026
Echinococcus granulosus snurportin 1 0.0217 0.175 0.2086
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0009 0.0028 0.0025
Schistosoma mansoni microtubule-associated protein tau 0.055 0.4509 0.5389
Trichomonas vaginalis D-aminoacylase, putative 0.0098 0.077 0.2702
Echinococcus granulosus Smad4 0.0018 0.0109 0.0122
Loa Loa (eye worm) hypothetical protein 0.0057 0.043 0.1325
Echinococcus granulosus o acyltransferase membrane bound domain 0.0011 0.0049 0.0051
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0018 0.0101 0.0191
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Brugia malayi Calcitonin receptor-like protein seb-1 0.0268 0.2172 0.6723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Trypanosoma cruzi serine/threonine protein phosphatase type 5, putative 0.0021 0.0127 0.1645
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0009 0.0029 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0044 0.005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0022 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0084 0.0652 0.0646
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Plasmodium vivax SET domain protein, putative 0.0045 0.0326 0.4178
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0022 0.0023
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0052 0.0059
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Brugia malayi Isocitrate dehydrogenase 0.0034 0.024 0.0736
Schistosoma mansoni ferritin light chain 0.0011 0.005 0.0056
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0138 0.017
Loa Loa (eye worm) hypothetical protein 0.0008 0.0021 0.0056
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0017 0.0097 0.0182
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0052 0.0153
Loa Loa (eye worm) hypothetical protein 0.0061 0.0463 0.1427
Loa Loa (eye worm) hypothetical protein 0.0008 0.0024 0.0068
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.024
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0569 0.7394
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.004 0.0286 0.0339
Loa Loa (eye worm) hypothetical protein 0.0074 0.0569 0.1756
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0009 0.0034 0.0038
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0037 0.0261 0.0254
Trypanosoma brucei prolyl endopeptidase 0.0009 0.0034 0.0411
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0013 0.0012
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0011 0.0049 0.0042
Plasmodium vivax serine/threonine kinase-1, putative 0.0042 0.0304 0.3894
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0062 0.0468 0.1444
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0014 0.0071 0.0889
Loa Loa (eye worm) hypothetical protein 0.003 0.0207 0.0634
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.0029 0.0095
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0052 0.0054
Giardia lamblia Alanyl dipeptidyl peptidase 0.0009 0.0034 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0022 0.0059
Trypanosoma brucei protein phosphatase 1, putative 0.0009 0.0029 0.035
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0006 0.0007 0.0012
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0009 0.0028 0.003
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0009 0.0034 0.0442
Brugia malayi mbt repeat family protein 0.0028 0.0184 0.0563
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0018 0.0103 0.1307
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0008 0.0022 0.0039
Giardia lamblia TCP-1 chaperonin subunit beta 0.0014 0.0071 0.0263
Plasmodium falciparum importin beta, putative 0.002 0.0124 0.2087
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0217 0.175 0.5416
Brugia malayi ImpB/MucB/SamB family protein 0.0032 0.0224 0.0687
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0022 0.0039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Plasmodium vivax flap endonuclease 1, putative 0.0018 0.0103 0.1256
Echinococcus granulosus microtubule associated protein 2 0.055 0.4509 0.5387
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0032 0.0224 0.0781
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0008 0.0022 0.0039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0085 0.0657 0.2029
Entamoeba histolytica vacuolar protein sorting 26 0.0011 0.0049 0.0293
Loa Loa (eye worm) hypothetical protein 0.0268 0.2172 0.6723
Entamoeba histolytica G protein alpha subunit, putative 0.0009 0.0028 0.0159
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha 0.0006 0.0002 0.0032
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0138 0.1796
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0628 0.5153 0.9782
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0062 0.0468 0.6084
Plasmodium vivax acyl-CoA synthetase, putative 0.0016 0.0085 0.1028
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0008 0.0022 0.0015
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0018 0.0101 0.0306
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Loa Loa (eye worm) prolyl oligopeptidase 0.0119 0.0938 0.2899
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0138 0.085
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0011 0.0049 0.0293
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0009 0.0034 0.0411
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0009 0.0028 0.0089
Loa Loa (eye worm) hypothetical protein 0.003 0.0208 0.0638
Schistosoma mansoni GTP-binding protein alpha subunit 0.0009 0.0028 0.003
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.0028 0.0021
Echinococcus multilocularis ets variant gene 4 0.0012 0.0052 0.0045
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0032 0.0224 0.0687
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0032 0.0224 0.0265
Entamoeba histolytica Flap nuclease, putative 0.0018 0.0103 0.0627
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0009 0.0028 0.0089
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0045 0.0326 0.0319
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0037 0.0261 0.3367
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0036 0.025 0.3252
Brugia malayi prolyl oligopeptidase family protein 0.0009 0.0034 0.0098
Loa Loa (eye worm) MH2 domain-containing protein 0.027 0.2194 0.6794
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0008 0.0022 0.0015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0129 0.0242
Echinococcus granulosus ewsr:fli fusion protein type 0.0012 0.0052 0.0054
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0009 0.0034 0.0442
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.001 0.0039 0.0351
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.024 0.2525
Schistosoma mansoni DNA polymerase IV / kappa 0.001 0.0039 0.0044
Treponema pallidum fructose-bisphosphate aldolase 0.0199 0.1601 1
Schistosoma mansoni hypothetical protein 0.0172 0.1378 0.1645
Echinococcus granulosus geminin 0.1016 0.8364 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0141 0.1806
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0028 0.0079
Echinococcus granulosus hypothetical protein 0.0041 0.0299 0.0349
Schistosoma mansoni GTP-binding protein alpha subunit 0.0009 0.0028 0.003
Echinococcus multilocularis dna polymerase eta 0.0047 0.0346 0.0339
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0027
Loa Loa (eye worm) Smad1 0.0018 0.0109 0.0329
Echinococcus granulosus cpg binding protein 0.0038 0.0273 0.0318
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0012 0.0052 0.0096
Loa Loa (eye worm) MBOAT family protein 0.0011 0.0049 0.0145
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0199 0.1601 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0098
Leishmania major DNA damage repair protein, putative 0.001 0.0039 0.0511
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0062 0.0468 0.6071
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Loa Loa (eye worm) TAR-binding protein 0.0147 0.1173 0.3628
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0129 0.0243
Onchocerca volvulus 0.0045 0.0326 0.0989
Brugia malayi beta-lactamase 0.0098 0.077 0.2378
Trichomonas vaginalis antibiotic synthetase, putative 0.0006 0.0007 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0022 0.0023
Brugia malayi Ets-domain containing protein 0.008 0.0616 0.1901
Brugia malayi RNA recognition motif domain containing protein 0.0147 0.1173 0.3628
Loa Loa (eye worm) hypothetical protein 0.0115 0.0909 0.281
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0129 0.0243
Brugia malayi transcription factor E74 isoform 0.0012 0.0052 0.0153
Onchocerca volvulus 0.0036 0.0256 0.0773
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0044 0.0037
Echinococcus multilocularis polycomb protein SCMH1 0.0028 0.0184 0.0177
Loa Loa (eye worm) hypothetical protein 0.0085 0.0657 0.2029
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0014 0.0071 0.0918
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0022 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0326 0.0386
Schistosoma mansoni smad1 5 8 and 0.0018 0.0109 0.0127
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0022 0.0023
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0062 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0233
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0031 0.0216 0.0209
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0138 0.0421
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0642 0.5267 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0153
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0009 0.0028 0.0021
Echinococcus granulosus ETS domain containing protein Elk 1 0.0012 0.0052 0.0054
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0009 0.0028 0.0079
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0009 0.0028 0.0025
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0008 0.0022 0.0015
Loa Loa (eye worm) hypothetical protein 0.0068 0.052 0.1605
Leishmania major DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0039 0.0481
Echinococcus granulosus survival motor neuron protein 1 0.0185 0.1489 0.1774
Schistosoma mansoni apoferritin-2 0.0011 0.005 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0468 0.2914
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.0009 0.0029 0.0027
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0011 0.0049 0.0056
Entamoeba histolytica protein phosphatase, putative 0.0012 0.0054 0.032
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.024 0.0736
Onchocerca volvulus 0.0028 0.0184 0.055
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.0028 0.003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0098 0.077 0.146
Schistosoma mansoni smad1 5 8 and 0.0018 0.0109 0.0127
Brugia malayi prolyl oligopeptidase family protein 0.0009 0.0034 0.0098
Echinococcus granulosus FTZ F1 alpha 0.0008 0.0022 0.0018
Trichomonas vaginalis helicase, putative 0.0008 0.0024 0.0076
Entamoeba histolytica protein kinase, putative 0.0062 0.0468 0.2914
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0098 0.077 0.2378
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0032 0.0224 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0008 0.0022 0.0059
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0022 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0141 0.1806
Trypanosoma brucei DNA damage repair protein, putative 0.001 0.0039 0.0481
Loa Loa (eye worm) mbt repeat family protein 0.0028 0.0184 0.0563
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0009 0.0028 0.003
Echinococcus multilocularis thyroid hormone receptor alpha 0.0008 0.0022 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0129 0.0392
Mycobacterium tuberculosis Probable lipase LipD 0.0098 0.077 0.146
Toxoplasma gondii hypothetical protein 0.0009 0.0034 0.0293
Schistosoma mansoni elf1 0.0012 0.0052 0.0059
Schistosoma mansoni protein phosphatase type 1 0.0009 0.0029 0.0032
Schistosoma mansoni coup transcription factor 0.0008 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0034 0.0111
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0008 0.0022 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Entamoeba histolytica Ran family GTPase 0.0015 0.008 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0034 0.0111
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0085 0.0657 0.0778
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.1298
Loa Loa (eye worm) RNA binding protein 0.0147 0.1173 0.3628
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.0145
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0085 0.0657 0.0778
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.024 0.0233
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0011 0.0049 0.0042
Brugia malayi steroid hormone receptor 0.0008 0.0022 0.0059
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0039 0.0481
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0022 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0022 0.0059
Brugia malayi RNA, U transporter 1 0.0058 0.0434 0.1338
Echinococcus multilocularis ETS transcription factor Elf 5 0.0012 0.0052 0.0045
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Onchocerca volvulus Protein ultraspiracle homolog 0.0008 0.0022 0.0046
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0097 0.0759 0.144
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0098 0.077 0.146
Loa Loa (eye worm) hypothetical protein 0.0183 0.1471 0.4551
Trichomonas vaginalis set domain proteins, putative 0.0349 0.2842 1
Plasmodium vivax DNA repair protein REV1, putative 0.001 0.0039 0.0425
Brugia malayi prolyl oligopeptidase family protein 0.0119 0.0938 0.2899
Echinococcus granulosus GPCR family 2 0.0085 0.0657 0.0778
Giardia lamblia DNA damage repair protein 0.001 0.0039 0.0064
Mycobacterium ulcerans thioesterase TesA 0.0015 0.0077 0.0145
Trichomonas vaginalis ferritin, putative 0.0011 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0031 0.0216 0.066
Schistosoma mansoni hypothetical protein 0.0012 0.0052 0.0059
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0018 0.0103 0.1038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Onchocerca volvulus 0.0009 0.0028 0.0065
Mycobacterium tuberculosis Conserved protein 0.0098 0.077 0.146
Trichomonas vaginalis penicillin-binding protein, putative 0.0098 0.077 0.2702
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0011 0.0049 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0141 0.1806
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0037 0.0261 0.1616
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.0044 0.0044
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0129 0.0243
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0015 0.008 0.079
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0037 0.0261 0.3388
Schistosoma mansoni cpg binding protein 0.0038 0.0273 0.0324
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0011 0.0049 0.0051
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0009 0.0034 0.0411
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.0029 0.0095
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0118 0.093 1
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.001 0.0037 0.0321
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0129 0.0392
Toxoplasma gondii type I fatty acid synthase, putative 0.0012 0.0059 0.0569
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0009 0.0028 0.0079
Echinococcus multilocularis SAM and MBT domain containing protein 0.0028 0.0184 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0036 0.025 0.0291
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0109 0.0102
Schistosoma mansoni protein phosphatase-7 0.0008 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.001 0.0039 0.0114
Loa Loa (eye worm) hypothetical protein 0.0045 0.0326 0.1002
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0009 0.0034 0.0038
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0142 0.0269
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Toxoplasma gondii ABC1 family protein 0.0098 0.077 0.8261
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0233
Echinococcus multilocularis Smad4 0.0018 0.0109 0.0102
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0024 0.0068
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0019 0.011 0.0208
Mycobacterium ulcerans beta-lactamase 0.0098 0.077 0.146
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0109 0.0329
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0085 0.0657 0.0651
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0014 0.0071 0.024
Brugia malayi hypothetical protein 0.0009 0.0028 0.0079
Entamoeba histolytica prolyl oligopeptidase family protein 0.0009 0.0034 0.0197
Brugia malayi serine/threonine protein phosphatase 5 0.002 0.0118 0.0358
Echinococcus multilocularis 0.0041 0.0299 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0304 0.0361
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0142 0.0434
Echinococcus granulosus GA binding protein alpha chain 0.008 0.0616 0.0729
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0279
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0097 0.0759 0.1439
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0138 0.0573
Schistosoma mansoni sex comb on midleg homolog 0.0028 0.0184 0.0217
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0006 0.0007 0.0058
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0037 0.0261 0.3388
Echinococcus multilocularis prolyl endopeptidase 0.0009 0.0034 0.0027
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.0224 0.289
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0031 0.0216 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0049 0.0165
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0009 0.0028 0.0021
Echinococcus granulosus mothers against decapentaplegic 6 0.0008 0.0024 0.0021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0299 0.0918
Trypanosoma cruzi oligopeptidase b 0.0009 0.0034 0.0442
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0027
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.0028 0.0021
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0109 0.0122
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0009 0.0028 0.0025
Brugia malayi Importin beta-1 subunit 0.002 0.0124 0.0377
Echinococcus granulosus transcription factor Dp 1 0.0021 0.0132 0.015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0078 0.0605 0.0721
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0138 0.1722
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.004 0.0286 0.3026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0098 0.077 0.0917
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0006 0.0006 0.001
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0022 0.0023
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0101 0.0191
Loa Loa (eye worm) hhat protein 0.0011 0.0049 0.0145
Mycobacterium ulcerans hypothetical protein 0.001 0.0039 0.0073
Toxoplasma gondii ImpB/MucB/SamB family protein 0.001 0.0039 0.0351
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0138 0.0131
Entamoeba histolytica deoxycytidyl transferase, putative 0.0032 0.0224 0.1387
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0022 0.0018
Schistosoma mansoni zinc finger protein 0.0011 0.0049 0.0056
Echinococcus multilocularis tar DNA binding protein 0.0147 0.1173 0.1167
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Onchocerca volvulus 0.0098 0.077 0.2367
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0006 0.0007 0.001
Plasmodium falciparum acyl-CoA synthetase 0.0016 0.0085 0.1394
Loa Loa (eye worm) fatty acid synthase 0.0017 0.0099 0.03
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0129 0.0243
Loa Loa (eye worm) hypothetical protein 0.0395 0.3229 1
Schistosoma mansoni ets-related 0.0242 0.1959 0.234
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0008 0.0022 0.0015
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.0028 0.003
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0008 0.0024 0.0054
Schistosoma mansoni DNA polymerase eta 0.0047 0.0346 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0049 0.0165
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0008 0.0022 0.0018
Onchocerca volvulus 0.0011 0.0049 0.0131
Trichomonas vaginalis chaperonin, putative 0.0014 0.0071 0.024
Onchocerca volvulus Bile acid receptor homolog 0.0008 0.0022 0.0046
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.024
Echinococcus multilocularis survival motor neuron protein 1 0.0185 0.1489 0.1483
Trypanosoma brucei chrX additional, unordered contigs 0.001 0.0039 0.0481
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0009 0.0034 0.0063
Mycobacterium tuberculosis Conserved protein 0.0098 0.077 0.146
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0036 0.025 0.0244
Brugia malayi Pre-SET motif family protein 0.0307 0.2492 0.7718
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.024 0.4147
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0013 0.006 0.0113
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0006 0.0007 0.0012
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0042 0.0304 0.393
Echinococcus granulosus flap endonuclease 1 0.0018 0.0103 0.0115
Brugia malayi hypothetical protein 0.003 0.0208 0.0638
Echinococcus multilocularis sterol O acyltransferase 1 0.0115 0.0909 0.0903
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0009 0.0028 0.0079
Loa Loa (eye worm) protein phosphatase 5 0.0019 0.0113 0.0342
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.025 0.0474
Echinococcus granulosus expressed protein 0.0009 0.0028 0.0025
Schistosoma mansoni ap endonuclease 0.0022 0.0138 0.0162
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0202 0.1623 0.5025
Brugia malayi MH1 domain containing protein 0.0018 0.0109 0.0329
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0098 0.077 0.146
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Trichomonas vaginalis transmembrane protein nessy, putative 0.0011 0.0049 0.0165
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0642 0.5267 1
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0009 0.0034 0.0442
Leishmania major protein kinase, putative 0.0042 0.0304 0.3949
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.0009 0.0029 0.0083
Schistosoma mansoni cpg binding protein 0.0036 0.0256 0.0303
Toxoplasma gondii aldehyde dehydrogenase 0.0036 0.025 0.2636
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0011 0.005 0.0092
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0014 0.0071 0.0082
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.004 0.0286 0.372
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Onchocerca volvulus 0.0009 0.0028 0.0065
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0153
Schistosoma mansoni ran 0.0015 0.008 0.0093
Trichomonas vaginalis ran, putative 0.0015 0.008 0.0273
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0011 0.0049 0.0042
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0019 0.011 0.0208
Echinococcus granulosus protein phosphatase 5 0.002 0.0118 0.0133
Brugia malayi Pre-SET motif family protein 0.0045 0.0326 0.1002
Echinococcus granulosus polycomb protein SCMH1 0.0028 0.0184 0.0212
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0011 0.0049 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Echinococcus multilocularis dna polymerase kappa 0.0032 0.0224 0.0217
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0042 0.0304 0.3949
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0304 0.0361
Mycobacterium tuberculosis Probable peptidase 0.0009 0.0034 0.0063
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0028 0.0184 0.055
Plasmodium falciparum serine/threonine protein phosphatase 5 0.002 0.0118 0.1975
Echinococcus granulosus ecdysone induced protein 78C 0.0008 0.0022 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0008 0.0022 0.0015
Schistosoma mansoni sterol O-acyltransferase 1 0.0115 0.0909 0.1084
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.009
Loa Loa (eye worm) CXXC zinc finger family protein 0.0036 0.0256 0.0785
Mycobacterium ulcerans thioesterase 0.0015 0.0077 0.0145
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Schistosoma mansoni smad 0.0018 0.0109 0.0127
Trypanosoma brucei serine/threonine protein phosphatase 5 0.0021 0.0127 0.1618
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0009 0.0028 0.0079
Leishmania major hypothetical protein, conserved 0.0098 0.077 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0008 0.0022 0.0059
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.024 0.3097
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0084 0.0652 0.0772
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.0009 0.0029 0.0022
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0138 0.0478
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0006 0.0007 0.001
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0019 0.011 0.0208
Trichomonas vaginalis protein phosphatase-1, putative 0.0012 0.0054 0.018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Brugia malayi Ets-domain containing protein 0.0012 0.0052 0.0153
Brugia malayi beta-lactamase family protein 0.0098 0.077 0.2378
Entamoeba histolytica acyl-coA synthetase, putative 0.0021 0.0129 0.0792
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.004 0.0286 0.372
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0024 0.0076
Echinococcus granulosus o acyltransferase membrane bound domain 0.0011 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0185 0.1489 0.4608
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0032 0.0224 0.2912
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0042 0.0304 0.3949
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0014 0.0071 0.0082
Echinococcus granulosus ETS transcription factor Elf 1 0.0012 0.0052 0.0054
Echinococcus granulosus beta LACTamase domain containing family member 0.0098 0.077 0.0913
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0569 0.7394
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0346 0.4493
Echinococcus granulosus dna polymerase kappa 0.0032 0.0224 0.026
Brugia malayi TAR-binding protein 0.0147 0.1173 0.3628
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0022 0.0059
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0098 0.077 0.2378
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.0322
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0022 0.0039
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0008 0.0022 0.0039
Trypanosoma cruzi glycerol uptake protein, putative 0.0011 0.0049 0.064
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0009 0.0029 0.0027
Echinococcus multilocularis ferritin 0.0011 0.005 0.0043
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0011 0.0049 0.0042
Trypanosoma cruzi prolyl endopeptidase 0.0009 0.0034 0.0442
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.024 0.2525
Mycobacterium tuberculosis Conserved protein 0.0098 0.077 0.146
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.1623 0.1618
Mycobacterium leprae conserved hypothetical protein 0.0098 0.077 0.1458
Giardia lamblia Kinase, CMGC CLK 0.0042 0.0304 0.1748
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0009 0.0034 0.0061
Brugia malayi T-complex protein 1, beta subunit 0.0014 0.0071 0.0211
Schistosoma mansoni acetyl-CoA synthetase 0.0006 0.0007 0.0005
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0392
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.077 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0036 0.025 0.0474
Trypanosoma brucei oligopeptidase b 0.0009 0.0034 0.0411
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0006 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Brugia malayi Fli-1 protein 0.0242 0.1959 0.6064
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.009
Trypanosoma cruzi DNA damage repair protein, putative 0.001 0.0039 0.0511
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0018 0.0101 0.0189
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0006 0.0007 0.0012
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0268 0.2172 0.6723
Trypanosoma brucei glycerol uptake protein, putative 0.0011 0.0049 0.061
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0304 0.1062
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Loa Loa (eye worm) hypothetical protein 0.001 0.0041 0.0118
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0008 0.0022 0.0039
Loa Loa (eye worm) MBOAT family protein 0.0011 0.0049 0.0145
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Treponema pallidum bacterioferrin (TpF1) 0.0011 0.005 0.0002
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0008 0.0022 0.0038
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0006 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0124 0.0377
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0018 0.0103 0.1335
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0014 0.0075 0.0141
Brugia malayi follicle stimulating hormone receptor 0.0395 0.3225 0.999
Echinococcus multilocularis importin subunit beta 1 0.002 0.0124 0.0117
Echinococcus granulosus tar DNA binding protein 0.0147 0.1173 0.1395
Entamoeba histolytica protein kinase, putative 0.0062 0.0468 0.2914
Leishmania major serine/threonine protein phosphatase type 5, putative 0.002 0.0118 0.1533
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Brugia malayi Protein kinase domain containing protein 0.0062 0.0468 0.1444
Brugia malayi polk-prov protein 0.001 0.0039 0.0114
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.009
Echinococcus granulosus tumor protein p63 0.0391 0.3193 0.3812
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0019 0.011 0.0206
Schistosoma mansoni protein phosphatase-1 0.0009 0.0029 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0062 0.0066
Loa Loa (eye worm) MBCTL1 0.0031 0.0216 0.066
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0224 0.0424
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Giardia lamblia DINP protein human, muc B family 0.0032 0.0224 0.124
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0009 0.0034 0.0197
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0037 0.0261 0.0801
Echinococcus multilocularis dual specificity protein kinase clk2 0.0042 0.0304 0.0297
Onchocerca volvulus 0.0098 0.077 0.2367
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0011 0.0049 0.0056
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0119 0.0938 0.289
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Loa Loa (eye worm) serine/threonine protein phosphatase 5 0.002 0.0118 0.0358
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0392
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0008 0.0022 0.0059
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0231 0.0268
Mycobacterium leprae Polyketide synthase Pks13 0.0026 0.0173 0.0325
Schistosoma mansoni aldehyde dehydrogenase 0.0036 0.025 0.0296
Loa Loa (eye worm) hypothetical protein 0.0104 0.0816 0.2522
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0038 0.0269 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0008 0.0022 0.0059
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.0009 0.0029 0.0294
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0642 0.5267 1
Echinococcus granulosus expressed protein 0.0011 0.005 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Schistosoma mansoni cpg binding protein 0.0038 0.0273 0.0324
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0326 0.0386
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0468 0.0557
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0022 0.0039
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.0009 0.0029 0.0022
Onchocerca volvulus 0.0009 0.0028 0.0065
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0109 0.0127
Loa Loa (eye worm) oxidoreductase 0.0006 0.0007 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0022 0.0015
Echinococcus granulosus dual specificity protein kinase clk2 0.0042 0.0304 0.0355
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.004 0.0286 0.3699
Echinococcus multilocularis mothers against decapentaplegic 2 0.0008 0.0024 0.0017
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0011 0.0049 0.0753
Loa Loa (eye worm) fli-1 protein 0.0242 0.1959 0.6064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0326 0.0386
Schistosoma mansoni hypothetical protein 0.0183 0.1471 0.1756
Schistosoma mansoni ap endonuclease 0.0022 0.0138 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0085 0.0657 0.0651
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0026 0.0173 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Leishmania major acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Trypanosoma cruzi GUP1, putative 0.0011 0.0049 0.064
Brugia malayi Steroid receptor seven-up type 2 0.0008 0.0022 0.0059
Mycobacterium ulcerans polyketide synthase Pks9 0.0012 0.0052 0.0097
Leishmania major serine/threonine protein phosphatase pp1(5.9), putative 0.0006 0.0002 0.0032
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0109 0.0102
Echinococcus granulosus prolyl endopeptidase 0.0009 0.0034 0.0032
Toxoplasma gondii HEAT repeat-containing protein 0.002 0.0124 0.1271
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0008 0.0022 0.0059
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0009 0.0029 0.0083
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0138 0.0157
Schistosoma mansoni protein phosphatase-5 0.0021 0.0127 0.0148
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0113 0.0891 0.1057
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Echinococcus granulosus SAM and MBT domain containing protein 0.0028 0.0184 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0008 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0009 0.0029 0.0083
Leishmania major DNA polymerase eta, putative 0.0025 0.0161 0.2092
Schistosoma mansoni hypothetical protein 0.0038 0.0269 0.0319
Schistosoma mansoni hypothetical protein 0.0011 0.0049 0.0056
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.024 0.3119
Trypanosoma cruzi DNA damage repair protein, putative 0.001 0.0039 0.0511
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0129 0.1676
Loa Loa (eye worm) beta-lactamase 0.0098 0.077 0.2378
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0037 0.0261 0.0304
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.077 1
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0011 0.0049 0.0145
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.0028 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0129 0.0243
Trypanosoma brucei DNA damage repair protein, putative 0.001 0.0039 0.0481
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0018 0.0101 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0034 0.0442
Brugia malayi mbt repeat family protein 0.0028 0.0184 0.0563
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0015 0.0077 0.0143
Schistosoma mansoni smad 0.0008 0.0024 0.0026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Schistosoma mansoni Smad4 0.0018 0.0109 0.0127
Echinococcus granulosus importin subunit beta 1 0.002 0.0124 0.014
Trypanosoma brucei DNA polymerase eta, putative 0.0047 0.0346 0.4475
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0009 0.0028 0.0089
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Echinococcus granulosus Dipeptidyl peptidase 9 0.004 0.0286 0.0334
Schistosoma mansoni sex comb on midleg homolog 0.0028 0.0184 0.0217
Trypanosoma cruzi importin beta-1 subunit, putative 0.0016 0.0092 0.1201
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0037 0.0261 0.3388
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0008 0.0022 0.0018
Brugia malayi MH1 domain containing protein 0.001 0.0041 0.0118
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Leishmania major DNA polymerase eta, putative 0.0047 0.0346 0.4493
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.004 0.0286 0.3699
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0129 0.0242
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0042 0.0304 0.393
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Schistosoma mansoni hypothetical protein 0.1016 0.8364 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0101 0.0191
Mycobacterium ulcerans fatty acid synthase Fas 0.0006 0.0002 0.0002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0147 0.1173 0.3628
Plasmodium falciparum DNA repair protein REV1, putative 0.001 0.0039 0.0577
Schistosoma mansoni ets-related 0.0012 0.0052 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Onchocerca volvulus 0.0008 0.0022 0.0045
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0011 0.0049 0.0051
Echinococcus multilocularis transcription factor Dp 1 0.0021 0.0132 0.0126
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0009 0.0034 0.0293
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.008 0.0616 0.1901
Mycobacterium ulcerans hypothetical protein 0.0098 0.077 0.146
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0011 0.0049 0.0056
Echinococcus multilocularis acylamino acid releasing enzyme 0.0009 0.0034 0.0027
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0014 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Trypanosoma brucei prolyl oligopeptidase, putative 0.0009 0.0034 0.0411
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0129 0.0392
Trichomonas vaginalis DNA polymerase eta, putative 0.0032 0.0224 0.0781
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0031 0.0216 0.025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0098
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0011 0.0049 0.0293
Brugia malayi photoreceptor-specific nuclear receptor 0.0008 0.0022 0.0059
Mycobacterium ulcerans acetyl-CoA synthetase 0.0006 0.0007 0.0012
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0042 0.0304 0.3949
Onchocerca volvulus 0.0349 0.2842 0.8799
Trichomonas vaginalis protein phosphatase-1, putative 0.0012 0.0054 0.018
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0129 0.0792
Echinococcus granulosus ferritin 0.0011 0.005 0.0051
Mycobacterium tuberculosis Probable lipase LipE 0.0098 0.077 0.146
Leishmania major GTP-binding protein, putative 0.0015 0.008 0.1038
Onchocerca volvulus 0.0038 0.0269 0.0813
Echinococcus granulosus smad 0.0018 0.0109 0.0122
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0138 0.1796
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0138 0.1796
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Brugia malayi prolyl oligopeptidase family protein 0.004 0.0286 0.088
Trypanosoma brucei unspecified product 0.0032 0.0224 0.289
Plasmodium vivax serine/threonine protein phosphatase 5, putative 0.002 0.0118 0.1456
Echinococcus multilocularis dual specificity 0.0062 0.0468 0.0462
Trichomonas vaginalis flap endonuclease-1, putative 0.0018 0.0103 0.0353
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0642 0.5267 1
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0022 0.0039
Echinococcus multilocularis cpg binding protein 0.0038 0.0273 0.0266
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.024 0.3097
Leishmania major protein kinase, putative 0.0042 0.0304 0.3949
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.024 0.3119
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.0224 0.289
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0019 0.011 0.0206
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0042 0.0304 0.3949
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0085 0.0657 0.2029
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0119 0.0938 0.1119
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.024 0.0454
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0009 0.0028 0.0079
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0008 0.0017
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0012 0.0052 0.0045
Leishmania major hypothetical protein, conserved 0.0074 0.0569 0.7394
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0014 0.0071 0.0076
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.1623 0.1934
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0307 0.2492 0.7718
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0022 0.0023
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0009 0.0029 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0326 0.0386
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.0009 0.0029 0.0381
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Schistosoma mansoni survival motor neuron protein 0.0038 0.0269 0.0319
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0011 0.005 0.0091
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0022 0.0023
Brugia malayi T-complex protein 1, beta subunit 0.0014 0.0071 0.0211
Echinococcus multilocularis ewsr:fli fusion protein type 0.0012 0.0052 0.0045
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0009 0.0034 0.0197
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0017 0.0097 0.0182
Entamoeba histolytica prolyl oligopeptidase family protein 0.0009 0.0034 0.0197
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0006 0.0007 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0022 0.0018
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.0044 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0034 0.0442
Echinococcus multilocularis tumor protein p63 0.0391 0.3193 0.3188
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0022 0.0015
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0018 0.0101 0.0191
Brugia malayi hypothetical protein 0.0084 0.0652 0.2014
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.024 0.3057
Leishmania major acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0392
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Onchocerca volvulus 0.0098 0.077 0.2367
Schistosoma mansoni protein phosphatase type 1 0.0009 0.0029 0.0032
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0009 0.0034 0.0442
Toxoplasma gondii prolyl endopeptidase 0.0009 0.0034 0.0293
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0014
Leishmania major T-complex protein 1, beta subunit, putative 0.0014 0.0071 0.0918
Trypanosoma cruzi GUP1, putative 0.0011 0.0049 0.064
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0011 0.0049 0.0145
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0118 0.093 0.1764
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0138 0.177
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0138 0.0693
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Mycobacterium leprae Probable lipase LipE 0.0098 0.077 0.1458
Echinococcus multilocularis snurportin 1 0.0217 0.175 0.1744
Brugia malayi RNA binding protein 0.0147 0.1173 0.3628
Brugia malayi MH2 domain containing protein 0.0018 0.0109 0.0329
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0008 0.0022 0.0059
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0015 0.008 0.1009
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0008 0.0022 0.0018
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0006 0.0007 0.0012
Schistosoma mansoni myelin transcription factor 1 myt1 0.0031 0.0216 0.0255
Echinococcus multilocularis GPCR, family 2 0.0085 0.0657 0.0651
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Brugia malayi MH2 domain containing protein 0.0018 0.0109 0.0329
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0129 0.0243
Brugia malayi MH2 domain containing protein 0.027 0.2194 0.6794
Entamoeba histolytica hypothetical protein 0.0062 0.0468 0.2914
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0569 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0395 0.3225 0.999
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.043 0.0511
Echinococcus multilocularis protein C ets 2 0.0012 0.0052 0.0045
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0022
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0009 0.0028 0.0079
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0009 0.0028 0.0079
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0022 0.0039
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0011 0.0049 0.0555
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0022 0.0023
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0045 0.0326 0.3452
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.025 0.0474
Echinococcus multilocularis GA binding protein alpha chain 0.008 0.0616 0.0609
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0142 0.0434
Entamoeba histolytica prolyl oligopeptidase family protein 0.0009 0.0034 0.0197
Entamoeba histolytica hypothetical protein 0.0016 0.0092 0.0563
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.0145
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0026 0.0173 0.0327
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0008 0.0022 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.1623 0.1939
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.1623 0.1939
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0014
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0009 0.0028 0.003
Loa Loa (eye worm) prolyl oligopeptidase 0.0009 0.0034 0.0098
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0009 0.0028 0.0021
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0052 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0022 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0098 0.077 0.2702
Loa Loa (eye worm) hypothetical protein 0.0061 0.0463 0.1427
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0062 0.0468 0.6084
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0039 0.0481
Echinococcus multilocularis protein phosphatase 5 0.002 0.0118 0.0111
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Toxoplasma gondii exonuclease III APE 0.0022 0.0138 0.1422
Trypanosoma brucei unspecified product 0.0022 0.0141 0.1806
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0037 0.0261 0.0801
Mycobacterium tuberculosis Probable thioesterase TesA 0.0015 0.0077 0.0145
Echinococcus multilocularis mothers against decapentaplegic 6 0.0008 0.0024 0.0017
Mycobacterium ulcerans hypothetical protein 0.0021 0.0129 0.0243
Plasmodium falciparum flap endonuclease 1 0.0018 0.0103 0.1704
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0129 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Brugia malayi hypothetical protein 0.0395 0.3229 1
Loa Loa (eye worm) MBOAT family protein 0.0011 0.0049 0.0145
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0028 0.0079
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0015 0.008 0.1038
Echinococcus multilocularis FTZ F1 alpha 0.0008 0.0022 0.0015
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0097 0.0759 0.144
Brugia malayi MH1 domain containing protein 0.0018 0.0109 0.0329
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0569 0.737
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0009 0.0028 0.003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0008 0.0022 0.0018
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0113 0.0891 0.0884
Echinococcus multilocularis flap endonuclease 1 0.0018 0.0103 0.0096
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0009 0.0029 0.0083
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Mycobacterium ulcerans polyketide synthase 0.0019 0.011 0.0208
Schistosoma mansoni importin beta-1 0.002 0.0124 0.0146
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0006 0.0007 0.0014
Echinococcus granulosus histone acetyltransferase MYST2 0.0031 0.0216 0.025
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.0224 0.289
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0052 0.0045
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0011 0.005 0.0092
Plasmodium falciparum protein serine/threonine kinase-1 0.0042 0.0304 0.5284
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.1623 0.1618
Mycobacterium ulcerans polyketide synthase 0.0018 0.0101 0.0191
Trichomonas vaginalis penicillin-binding protein, putative 0.0098 0.077 0.2702
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0015 0.008 0.0073
Trichomonas vaginalis porcupine, putative 0.0011 0.0049 0.0165
Echinococcus granulosus o acyltransferase membrane bound domain 0.0011 0.0049 0.0051
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0129 0.0243
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.1623 0.1934
Giardia lamblia Flap structure-specific endonuclease 0.0018 0.0103 0.0467
Brugia malayi isocitrate dehydrogenase 0.0034 0.024 0.0736
Schistosoma mansoni hypothetical protein 0.1016 0.8364 1
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0009 0.0028 0.0079
Loa Loa (eye worm) hypothetical protein 0.0047 0.0346 0.1064
Plasmodium vivax hypothetical protein, conserved 0.0098 0.077 1
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.0009 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0109
Trypanosoma cruzi glycerol uptake protein, putative 0.0011 0.0049 0.064
Brugia malayi beta-lactamase family protein 0.0098 0.077 0.2378
Schistosoma mansoni gabp alpha 0.008 0.0616 0.0734
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0019 0.011 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0022 0.0059
Brugia malayi Ser/Thr protein phosphatase family protein 0.0008 0.0026 0.0072
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0138 0.2336
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0138 0.0421
Brugia malayi Protein kinase domain containing protein 0.0042 0.0304 0.0934
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0009 0.0028 0.0079
Schistosoma mansoni smad1 5 8 and 0.0018 0.0109 0.0127
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Loa Loa (eye worm) steroid hormone receptor 0.0008 0.0022 0.0059
Onchocerca volvulus 0.0021 0.0129 0.0379
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0042 0.0304 0.3217
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0009 0.0034 0.0063
Echinococcus multilocularis smad 0.0018 0.0109 0.0102
Brugia malayi diacylglycerol acyltransferase 0.0011 0.0049 0.0145
Toxoplasma gondii type I fatty acid synthase, putative 0.0019 0.0117 0.1196
Trypanosoma cruzi DNA polymerase eta, putative 0.0025 0.0161 0.2092
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.001 0.0039 0.0072
Trypanosoma brucei unspecified product 0.0022 0.0141 0.1806
Trichomonas vaginalis protein phosphatase-1, putative 0.0009 0.0029 0.0095
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0011 0.0049 0.0056
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Echinococcus multilocularis expressed protein 0.0011 0.005 0.0043
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0028 0.003
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0034 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Schistosoma mansoni hypothetical protein 0.0033 0.0231 0.0273
Echinococcus granulosus dual specificity 0.0062 0.0468 0.0552
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0014 0.0073 0.0135
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0009 0.0028 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Brugia malayi Latrophilin receptor protein 2 0.0085 0.0657 0.2029
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0039 0.0511
Leishmania major DNA polymerase kappa, putative 0.001 0.0039 0.0511
Trypanosoma cruzi glycerol uptake protein, putative 0.0011 0.0049 0.064
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0042 0.0304 0.0934
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0052 0.0153
Echinococcus multilocularis histone acetyltransferase MYST2 0.0031 0.0216 0.0209
Brugia malayi prolyl oligopeptidase family protein 0.0009 0.0034 0.0098
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0012 0.0052 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0039 0.0481
Leishmania major hypothetical protein, conserved 0.0011 0.0049 0.064
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0062 0.0185
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0014 0.0071 0.0427
Schistosoma mansoni apoferritin-2 0.0011 0.005 0.0056
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.093 0.1764
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.004 0.0286 0.372
Brugia malayi Ets-domain containing protein 0.008 0.0616 0.1901
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0092 0.0317
Onchocerca volvulus 0.0057 0.043 0.1313
Toxoplasma gondii t-complex protein beta subunit 0.0014 0.0071 0.069
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0052 0.0153
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0011 0.0049 0.0051
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.024 0.0233
Echinococcus granulosus acylamino acid releasing enzyme 0.0009 0.0034 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0098 0.077 0.0917
Mycobacterium ulcerans DNA polymerase IV 0.0032 0.0224 0.0424
Schistosoma mansoni protein phosphatase-1 0.0009 0.0029 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0231 0.0224
Brugia malayi DNA-binding protein D-ETS-3 0.0012 0.0052 0.0153
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Schistosoma mansoni flap endonuclease-1 0.0016 0.0089 0.0103
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0009 0.0034 0.0111
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0346 0.1064
Plasmodium vivax importin-beta 2, putative 0.002 0.0124 0.1538
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0028 0.0079
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Brugia malayi MH1 domain containing protein 0.001 0.0041 0.0118
Brugia malayi G-protein alpha subunit 0.0009 0.0028 0.0079
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0109 0.0329
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0326 0.0381
Loa Loa (eye worm) transcription factor SMAD2 0.027 0.2194 0.6794
Loa Loa (eye worm) G protein alpha subunit 3 0.0009 0.0028 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0085 0.016
Echinococcus multilocularis Dipeptidyl peptidase 9 0.004 0.0286 0.028
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0202 0.1623 0.5025
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0015 0.008 0.0956
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0009 0.0034 0.0038
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0014 0.0073 0.0137
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.025 0.0474
Brugia malayi nuclear receptor NHR-88 0.0008 0.0022 0.0059
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0028 0.003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0233
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0124 0.1587
Onchocerca volvulus 0.0037 0.0259 0.0784
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0011 0.0049 0.0459
Brugia malayi CXXC zinc finger family protein 0.0036 0.0256 0.0785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0009 0.0028 0.0089
Onchocerca volvulus Prolyl endopeptidase homolog 0.0009 0.0034 0.0084
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0044 0.0044
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.024 0.3119
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Echinococcus granulosus dna polymerase eta 0.0047 0.0346 0.0405
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0011 0.0049 0.0459

Activities

Activity type Activity value Assay description Source Reference
IZ (functional) = 0.04 millimeter Antimicrobial activity against Escherichia coli at 1 umol/disk after 24 hrs by disk diffusion assay ChEMBL. 19926364
IZ (functional) = 7 millimeter Antimicrobial activity against Escherichia coli at 10 ug/disk after 24 hrs by disk diffusion assay ChEMBL. 19926364
MBC (functional) = 34.6 10'-2micromol/ml Antimicrobial activity against Escherichia coli after 24 hrs by microdilution technique ChEMBL. 19926364
MIC (functional) = 17.3 10'-2micromol/ml Antimicrobial activity against Escherichia coli after 24 hrs by microdilution technique ChEMBL. 19926364

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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