Detailed information for compound 1077122

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 577.638 | Formula: C34H27N9O
  • H donors: 4 H acceptors: 5 LogP: 7.71 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#Cc1c(N)nc(cc1c1ccccc1OC)c1ccc(cc1)Nc1nc(Nc2ccccc2)nc(n1)Nc1ccccc1
  • InChi: 1S/C34H27N9O/c1-44-30-15-9-8-14-26(30)27-20-29(40-31(36)28(27)21-35)22-16-18-25(19-17-22)39-34-42-32(37-23-10-4-2-5-11-23)41-33(43-34)38-24-12-6-3-7-13-24/h2-20H,1H3,(H2,36,40)(H3,37,38,39,41,42,43)
  • InChiKey: BIQPPACOXIKXOX-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0118 0.093 1
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0011 0.005 0.047
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0279
Echinococcus multilocularis ETS transcription factor Elf 1 0.0012 0.0052 0.0045
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.0028 0.003
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.024 0.0233
Loa Loa (eye worm) hypothetical protein 0.0185 0.1489 0.4608
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0569 0.7394
Schistosoma mansoni hypothetical protein 0.0084 0.0652 0.0777
Trypanosoma cruzi serine/threonine protein phosphatase type 5, putative 0.0021 0.0127 0.1645
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0006 0.0007 0.0012
Plasmodium vivax DNA repair protein REV1, putative 0.001 0.0039 0.0425
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.024 0.2525
Trichomonas vaginalis protein phosphatase-1, putative 0.0012 0.0054 0.018
Onchocerca volvulus 0.0009 0.0028 0.0065
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.0009 0.0029 0.0381
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.0009 0.0029 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.093 0.1764
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0044 0.005
Loa Loa (eye worm) hypothetical protein 0.0061 0.0463 0.1427
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0034 0.0111
Toxoplasma gondii ABC1 family protein 0.0098 0.077 0.8261
Leishmania major hypothetical protein, conserved 0.0074 0.0569 0.7394
Echinococcus multilocularis cpg binding protein 0.0038 0.0273 0.0266
Trypanosoma cruzi GUP1, putative 0.0011 0.0049 0.064
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0202 0.1623 0.5025
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0129 0.0243
Trichomonas vaginalis set domain proteins, putative 0.0349 0.2842 1
Trypanosoma brucei unspecified product 0.0022 0.0141 0.1806
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.0322
Plasmodium vivax acyl-CoA synthetase, putative 0.0016 0.0085 0.1028
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0642 0.5267 1
Schistosoma mansoni protein phosphatase type 1 0.0009 0.0029 0.0032
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0011 0.0049 0.0056
Echinococcus granulosus o acyltransferase membrane bound domain 0.0011 0.0049 0.0051
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0008 0.0022 0.0015
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0018 0.0101 0.0189
Echinococcus granulosus dna polymerase kappa 0.0032 0.0224 0.026
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0028 0.0184 0.0217
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0022 0.0015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0216 0.066
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Echinococcus granulosus o acyltransferase membrane bound domain 0.0011 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0068 0.052 0.1605
Loa Loa (eye worm) hypothetical protein 0.0047 0.0346 0.1064
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0098 0.077 0.0917
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Echinococcus multilocularis expressed protein 0.0009 0.0028 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.025 0.0474
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0129 0.1676
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0011 0.0049 0.0056
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0026 0.0173 0.0327
Onchocerca volvulus Protein ultraspiracle homolog 0.0008 0.0022 0.0046
Schistosoma mansoni ets-related 0.0242 0.1959 0.234
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0022 0.0059
Entamoeba histolytica hypothetical protein 0.0062 0.0468 0.2914
Trichomonas vaginalis penicillin-binding protein, putative 0.0098 0.077 0.2702
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0009 0.0029 0.0022
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Echinococcus granulosus ferritin 0.0011 0.005 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0142 0.0434
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0009 0.0029 0.0095
Entamoeba histolytica protein kinase, putative 0.0062 0.0468 0.2914
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0009 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0009 0.0028 0.003
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.024 0.0454
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0124 0.1587
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0037 0.0261 0.3388
Trypanosoma cruzi prolyl endopeptidase 0.0009 0.0034 0.0442
Onchocerca volvulus 0.0008 0.0022 0.0046
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.024 0.3097
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0011 0.0049 0.0459
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0009 0.0034 0.0063
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0006 0.0006 0.001
Entamoeba histolytica protein phosphatase, putative 0.0012 0.0054 0.032
Entamoeba histolytica hypothetical protein, conserved 0.0009 0.0034 0.0197
Echinococcus multilocularis SAM and MBT domain containing protein 0.0028 0.0184 0.0177
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0233
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0101 0.0191
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0039 0.0481
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0224 0.0424
Leishmania major DNA polymerase kappa, putative 0.001 0.0039 0.0511
Echinococcus multilocularis geminin 0.1016 0.8364 0.8363
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0011 0.0049 0.0753
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0052 0.0153
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.0058
Brugia malayi MH1 domain containing protein 0.001 0.0041 0.0118
Schistosoma mansoni myelin transcription factor 1 myt1 0.0031 0.0216 0.0255
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0129 0.0242
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0032 0.0224 0.0687
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.004 0.0286 0.372
Brugia malayi Latrophilin receptor protein 2 0.0085 0.0657 0.2029
Loa Loa (eye worm) MH2 domain-containing protein 0.027 0.2194 0.6794
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0014 0.0071 0.0889
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0008 0.0022 0.0059
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0008 0.0022 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0097 0.0759 0.144
Brugia malayi nuclear hormone receptor 0.0008 0.0022 0.0059
Trypanosoma brucei glycerol uptake protein, putative 0.0011 0.0049 0.061
Leishmania major DNA damage repair protein, putative 0.001 0.0039 0.0511
Toxoplasma gondii type I fatty acid synthase, putative 0.0019 0.0117 0.1196
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0569 0.6088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0008 0.0022 0.0059
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0037 0.0261 0.0801
Entamoeba histolytica deoxycytidyl transferase, putative 0.0032 0.0224 0.1387
Brugia malayi Steroid receptor seven-up type 2 0.0008 0.0022 0.0059
Trichomonas vaginalis helicase, putative 0.0008 0.0024 0.0076
Trypanosoma brucei DNA damage repair protein, putative 0.001 0.0039 0.0481
Mycobacterium leprae Probable lipase LipE 0.0098 0.077 0.1458
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0009 0.0034 0.0293
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0015 0.008 0.1009
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0129 0.1676
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0018 0.0101 0.0191
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0138 0.0261
Onchocerca volvulus 0.0011 0.0049 0.0131
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0062 0.0468 0.6071
Onchocerca volvulus 0.0098 0.077 0.2367
Echinococcus granulosus protein phosphatase 5 0.002 0.0118 0.0133
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0022 0.0039
Echinococcus multilocularis smad 0.0018 0.0109 0.0102
Trypanosoma cruzi importin beta-1 subunit, putative 0.0016 0.0092 0.1201
Trypanosoma brucei serine/threonine protein phosphatase 5 0.0021 0.0127 0.1618
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0009 0.0028 0.0079
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0026 0.0173 0.0327
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0014 0.0071 0.0427
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0052 0.0059
Trichomonas vaginalis protein phosphatase-5, putative 0.0012 0.0054 0.018
Echinococcus granulosus importin subunit beta 1 0.002 0.0124 0.014
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.024
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0037 0.0261 0.1616
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0008 0.0022 0.0039
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0011 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Echinococcus multilocularis GPCR, family 2 0.0085 0.0657 0.0651
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.0009 0.0029 0.0399
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0037 0.0261 0.3367
Brugia malayi prolyl oligopeptidase family protein 0.0009 0.0034 0.0098
Echinococcus multilocularis prolyl endopeptidase 0.0009 0.0034 0.0027
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0129 0.0243
Toxoplasma gondii serine/threonine phosophatase PP1 0.0009 0.0029 0.0243
Brugia malayi prolyl oligopeptidase family protein 0.0009 0.0034 0.0098
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0032 0.0224 0.0217
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0011 0.0049 0.0293
Echinococcus granulosus ecdysone induced protein 78C 0.0008 0.0022 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0084 0.0652 0.0772
Giardia lamblia TCP-1 chaperonin subunit beta 0.0014 0.0071 0.0263
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0008 0.0022 0.0039
Brugia malayi serine/threonine protein phosphatase 5 0.002 0.0118 0.0358
Brugia malayi beta-lactamase family protein 0.0098 0.077 0.2378
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.1623 0.1939
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0013 0.0012
Mycobacterium ulcerans polyketide synthase 0.0018 0.0101 0.0191
Plasmodium vivax flap endonuclease 1, putative 0.0018 0.0103 0.1256
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0009 0.0029 0.0083
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0009 0.0028 0.0079
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0009 0.0028 0.0079
Plasmodium falciparum T-complex protein 1 subunit beta 0.0014 0.0071 0.1133
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Schistosoma mansoni apoferritin-2 0.0011 0.005 0.0056
Schistosoma mansoni Smad4 0.0018 0.0109 0.0127
Brugia malayi RNA binding protein 0.0147 0.1173 0.3628
Plasmodium vivax importin-beta 2, putative 0.002 0.0124 0.1538
Loa Loa (eye worm) RNA binding protein 0.0147 0.1173 0.3628
Mycobacterium ulcerans DNA polymerase IV 0.0032 0.0224 0.0424
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0042 0.0304 0.3949
Schistosoma mansoni aldehyde dehydrogenase 0.0036 0.025 0.0296
Echinococcus granulosus beta LACTamase domain containing family member 0.0098 0.077 0.0913
Mycobacterium ulcerans thioesterase TesA 0.0015 0.0077 0.0145
Trypanosoma brucei unspecified product 0.0022 0.0141 0.1806
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.1623 0.1939
Entamoeba histolytica hypothetical protein 0.0016 0.0092 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.0044 0.0037
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0008 0.0022 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Echinococcus granulosus tar DNA binding protein 0.0147 0.1173 0.1395
Echinococcus granulosus expressed protein 0.0011 0.005 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Schistosoma mansoni flap endonuclease-1 0.0016 0.0089 0.0103
Loa Loa (eye worm) MBOAT family protein 0.0011 0.0049 0.0145
Mycobacterium tuberculosis Probable lipase LipD 0.0098 0.077 0.146
Echinococcus multilocularis ferritin 0.0011 0.005 0.0043
Loa Loa (eye worm) hypothetical protein 0.001 0.0039 0.0114
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0326 0.0381
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0022 0.0059
Onchocerca volvulus 0.0395 0.3229 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0032 0.0224 0.0424
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Toxoplasma gondii serine/threonine protein phosphatase 0.002 0.0118 0.1203
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0022
Leishmania major hypothetical protein, conserved 0.0011 0.0049 0.064
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0022 0.0023
Echinococcus multilocularis sterol O acyltransferase 1 0.0115 0.0909 0.0903
Trypanosoma brucei DNA polymerase eta, putative 0.0047 0.0346 0.4475
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0097 0.0759 0.1439
Brugia malayi hypothetical protein 0.0185 0.1489 0.4608
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0018 0.0101 0.0191
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0011 0.0049 0.0042
Giardia lamblia Flap structure-specific endonuclease 0.0018 0.0103 0.0467
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0011 0.0049 0.0042
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0006 0.0003 0.0004
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0012 0.0052 0.0096
Echinococcus granulosus prolyl endopeptidase 0.0009 0.0034 0.0032
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0009 0.0028 0.0025
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0042 0.0304 0.3949
Echinococcus multilocularis flap endonuclease 1 0.0018 0.0103 0.0096
Loa Loa (eye worm) hypothetical protein 0.003 0.0208 0.0638
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0018 0.0101 0.0306
Schistosoma mansoni microtubule-associated protein tau 0.055 0.4509 0.5389
Loa Loa (eye worm) hypothetical protein 0.0104 0.0816 0.2522
Brugia malayi isocitrate dehydrogenase 0.0034 0.024 0.0736
Giardia lamblia Alanyl dipeptidyl peptidase 0.0009 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Echinococcus granulosus polycomb protein SCMH1 0.0028 0.0184 0.0212
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0395 0.3225 0.999
Toxoplasma gondii ImpB/MucB/SamB family protein 0.001 0.0039 0.0351
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0009 0.0028 0.0025
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0109 0.0122
Trypanosoma brucei prolyl endopeptidase 0.0009 0.0034 0.0411
Trypanosoma cruzi serine/threonine protein phosphatase type 5, putative 0.0021 0.0127 0.1645
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.004 0.0286 0.0339
Mycobacterium tuberculosis Conserved protein 0.0098 0.077 0.146
Brugia malayi MH1 domain containing protein 0.0018 0.0109 0.0329
Mycobacterium ulcerans hypothetical protein 0.0118 0.093 0.1764
Echinococcus multilocularis microtubule associated protein 2 0.055 0.4509 0.4505
Brugia malayi hypothetical protein 0.0048 0.0352 0.1083
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0199 0.1601 1
Mycobacterium ulcerans acetyl-CoA synthetase 0.0006 0.0007 0.0012
Brugia malayi prolyl oligopeptidase family protein 0.0009 0.0034 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0049 0.0165
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0009 0.0034 0.0197
Trypanosoma cruzi DNA polymerase eta, putative 0.0025 0.0161 0.2092
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0129 0.0243
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0011 0.0049 0.0051
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0006 0.0007 0.0014
Schistosoma mansoni GTP-binding protein alpha subunit 0.0009 0.0028 0.003
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0326 0.0386
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0008 0.0022 0.0015
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0011 0.0049 0.0555
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.001 0.0037 0.0321
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0018 0.0103 0.1038
Echinococcus granulosus cpg binding protein 0.0038 0.0273 0.0318
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.0224 0.289
Trypanosoma cruzi DNA damage repair protein, putative 0.001 0.0039 0.0511
Brugia malayi beta-lactamase 0.0098 0.077 0.2378
Echinococcus granulosus o acyltransferase membrane bound domain 0.0011 0.0049 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0009 0.0028 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0129 0.0243
Loa Loa (eye worm) CXXC zinc finger family protein 0.0036 0.0256 0.0785
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0037 0.0261 0.0309
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0052 0.0054
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0092 0.0317
Mycobacterium tuberculosis Probable peptidase 0.0009 0.0034 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0015 0.008 0.0073
Trichomonas vaginalis antibiotic synthetase, putative 0.0006 0.0007 0.0016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.1623 0.1618
Loa Loa (eye worm) hypothetical protein 0.0115 0.0909 0.281
Loa Loa (eye worm) transcription factor SMAD2 0.027 0.2194 0.6794
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0028 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.009
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0006 0.0007 0.0028
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0129 0.0242
Schistosoma mansoni smad 0.0008 0.0024 0.0026
Loa Loa (eye worm) latrophilin receptor protein 2 0.0085 0.0657 0.2029
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0009 0.0028 0.0079
Loa Loa (eye worm) hypothetical protein 0.0074 0.0569 0.1756
Trypanosoma cruzi glycerol uptake protein, putative 0.0011 0.0049 0.064
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0062 0.0055
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.024 0.0284
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0011 0.0049 0.0051
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0011 0.0049 0.0042
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0007 0.0015 0.0027
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0011 0.0049 0.0051
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Entamoeba histolytica vacuolar protein sorting 26 0.0011 0.0049 0.0293
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.004 0.0286 0.3026
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0014 0.0071 0.0918
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Brugia malayi Protein kinase domain containing protein 0.0042 0.0304 0.0934
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0009 0.0034 0.0411
Leishmania major T-complex protein 1, beta subunit, putative 0.0014 0.0071 0.0918
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0138 0.2336
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0022 0.0023
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0037 0.0261 0.0254
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0032 0.0224 0.0781
Loa Loa (eye worm) T-complex protein 1 0.0014 0.0071 0.0211
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0031 0.0216 0.025
Brugia malayi T-complex protein 1, beta subunit 0.0014 0.0071 0.0211
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.024 0.3119
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Brugia malayi Smad1 0.0018 0.0109 0.0329
Onchocerca volvulus 0.0021 0.0129 0.0379
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0012 0.0052 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0008 0.0022 0.0059
Schistosoma mansoni cpg binding protein 0.0036 0.0256 0.0303
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0138 0.1796
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Treponema pallidum fructose-bisphosphate aldolase 0.0199 0.1601 1
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.001 0.0039 0.0072
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0037 0.0261 0.3388
Echinococcus multilocularis dual specificity protein kinase clk2 0.0042 0.0304 0.0297
Echinococcus multilocularis protein phosphatase 5 0.002 0.0118 0.0111
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.0044 0.0044
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0009 0.0029 0.0095
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0052 0.0045
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0022 0.0023
Brugia malayi beta-lactamase family protein 0.0098 0.077 0.2378
Trypanosoma cruzi oligopeptidase b 0.0009 0.0034 0.0442
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.009
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0015 0.0077 0.0143
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.0145
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0009 0.0034 0.0411
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0468 0.2914
Schistosoma mansoni ap endonuclease 0.0022 0.0138 0.0162
Giardia lamblia Kinase, CMGC CLK 0.0042 0.0304 0.1748
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0039 0.0481
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Leishmania major serine/threonine protein phosphatase pp1(5.9), putative 0.0006 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.0145
Trichomonas vaginalis chaperonin, putative 0.0014 0.0071 0.024
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0009 0.0034 0.0442
Schistosoma mansoni hypothetical protein 0.0217 0.175 0.209
Echinococcus granulosus protein C ets 2 0.0012 0.0052 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0006 0.0002 0.0002
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0052 0.0153
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0006 0.0007 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0129 0.0243
Schistosoma mansoni ran 0.0015 0.008 0.0093
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0022
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0032 0.0224 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0141 0.1806
Schistosoma mansoni hypothetical protein 0.0033 0.0231 0.0273
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0307 0.2492 0.7718
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0008 0.0022 0.0038
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0346 0.4493
Schistosoma mansoni hypothetical protein 0.0038 0.0269 0.0319
Echinococcus granulosus microtubule associated protein 2 0.055 0.4509 0.5387
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.0028 0.0021
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0009 0.0029 0.0027
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0011 0.0049 0.0042
Echinococcus granulosus ETS transcription factor Elf 1 0.0012 0.0052 0.0054
Onchocerca volvulus 0.0008 0.0022 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Echinococcus multilocularis dna polymerase kappa 0.0032 0.0224 0.0217
Brugia malayi T-complex protein 1, beta subunit 0.0014 0.0071 0.0211
Schistosoma mansoni hypothetical protein 0.0172 0.1378 0.1645
Mycobacterium ulcerans thioesterase 0.0015 0.0077 0.0145
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0011 0.0049 0.0145
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0028 0.0184 0.055
Schistosoma mansoni sex comb on midleg homolog 0.0028 0.0184 0.0217
Loa Loa (eye worm) fatty acid synthase 0.0017 0.0099 0.03
Echinococcus multilocularis beta LACTamase domain containing family member 0.0098 0.077 0.0763
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0569 0.7385
Trichomonas vaginalis protein phosphatase-1, putative 0.0009 0.0029 0.0095
Echinococcus multilocularis Smad4 0.0018 0.0109 0.0102
Plasmodium falciparum DNA repair protein REV1, putative 0.001 0.0039 0.0577
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.024 0.0233
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0011 0.0049 0.0293
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0326 0.0386
Plasmodium falciparum importin beta, putative 0.002 0.0124 0.2087
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.024 0.0736
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0014 0.0075 0.0141
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0011 0.0049 0.0056
Echinococcus multilocularis tumor protein p63 0.0391 0.3193 0.3188
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0028 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Loa Loa (eye worm) beta-lactamase 0.0098 0.077 0.2378
Brugia malayi diacylglycerol acyltransferase 0.0011 0.0049 0.0145
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0009 0.0034 0.0038
Brugia malayi nuclear receptor NHR-88 0.0008 0.0022 0.0059
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0019 0.011 0.0208
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0009 0.0028 0.003
Echinococcus multilocularis mothers against decapentaplegic 2 0.0008 0.0024 0.0017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0062 0.0066
Schistosoma mansoni aldehyde dehydrogenase 0.0036 0.025 0.0296
Schistosoma mansoni hypothetical protein 0.1016 0.8364 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0109 0.0127
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.1298
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0042 0.0304 0.3949
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0011 0.005 0.0091
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0138 0.0131
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Plasmodium falciparum flap endonuclease 1 0.0018 0.0103 0.1704
Trypanosoma cruzi glycerol uptake protein, putative 0.0011 0.0049 0.064
Onchocerca volvulus 0.0098 0.077 0.2367
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.0029 0.0095
Entamoeba histolytica prolyl oligopeptidase family protein 0.0009 0.0034 0.0197
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0006 0.0007 0.001
Leishmania major DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Echinococcus multilocularis acylamino acid releasing enzyme 0.0009 0.0034 0.0027
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Brugia malayi Pre-SET motif family protein 0.0045 0.0326 0.1002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Schistosoma mansoni cpg binding protein 0.0038 0.0273 0.0324
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0031 0.0216 0.0209
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0006 0.0007 0.001
Loa Loa (eye worm) steroid hormone receptor 0.0008 0.0022 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0011 0.0049 0.0459
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0061 0.0182
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0009 0.0034 0.0063
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0109 0.0122
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0129 0.0792
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0007 0.0014
Loa Loa (eye worm) serine/threonine protein phosphatase 5 0.002 0.0118 0.0358
Trichomonas vaginalis D-aminoacylase, putative 0.0098 0.077 0.2702
Toxoplasma gondii prolyl endopeptidase 0.0009 0.0034 0.0293
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0008 0.0022 0.0018
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0346 0.1064
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0085 0.016
Schistosoma mansoni smad 0.0018 0.0109 0.0127
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0006 0.0007 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.1623 0.1939
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0569 1
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0009 0.0029 0.0083
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0098 0.077 0.146
Echinococcus granulosus ETS domain containing protein Elk 1 0.0012 0.0052 0.0054
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0011 0.0049 0.0145
Entamoeba histolytica hypothetical protein, conserved 0.0011 0.0049 0.0293
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0042 0.0304 0.3217
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0142 0.0269
Giardia lamblia Fructose-bisphosphate aldolase 0.0199 0.1601 1
Schistosoma mansoni sex comb on midleg homolog 0.0028 0.0184 0.0217
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0129 0.0243
Schistosoma mansoni hypothetical protein 0.0011 0.0049 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0034 0.0111
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0022 0.0023
Echinococcus multilocularis 0.0041 0.0299 0.0292
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0042 0.0304 0.393
Echinococcus multilocularis histone acetyltransferase MYST2 0.0031 0.0216 0.0209
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0008 0.0022 0.0039
Schistosoma mansoni elf1 0.0012 0.0052 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0028 0.0079
Schistosoma mansoni ets-related 0.0012 0.0052 0.0059
Echinococcus multilocularis ewsr:fli fusion protein type 0.0012 0.0052 0.0045
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0033 0.0231 0.0709
Mycobacterium leprae Polyketide synthase Pks13 0.0026 0.0173 0.0325
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0642 0.5267 1
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0011 0.0049 0.0042
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0097 0.0759 0.144
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.0224 0.289
Brugia malayi hypothetical protein 0.0009 0.0028 0.0079
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Loa Loa (eye worm) hypothetical protein 0.0045 0.0326 0.1002
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0642 0.5267 1
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0012 0.0052 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.025 0.0474
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0009 0.0028 0.003
Plasmodium vivax hypothetical protein, conserved 0.0098 0.077 1
Schistosoma mansoni hypothetical protein 0.0012 0.0052 0.0059
Brugia malayi latrophilin 2 splice variant baaae 0.0183 0.1471 0.4551
Echinococcus granulosus SAM and MBT domain containing protein 0.0028 0.0184 0.0212
Mycobacterium tuberculosis Probable hydrolase 0.0098 0.077 0.146
Schistosoma mansoni ets 0.0012 0.0052 0.0059
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0569 0.737
Trichomonas vaginalis porcupine, putative 0.0011 0.0049 0.0165
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.008 0.0616 0.1901
Brugia malayi polk-prov protein 0.001 0.0039 0.0114
Plasmodium falciparum acyl-CoA synthetase 0.0016 0.0085 0.1394
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0014 0.0071 0.0082
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0044 0.0037
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0009 0.0028 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.024 0.3119
Onchocerca volvulus 0.0009 0.0028 0.0065
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0018 0.0103 0.1307
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0011 0.0049 0.0051
Schistosoma mansoni zinc finger protein 0.0011 0.0049 0.0056
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0042 0.0304 0.0934
Entamoeba histolytica Ran family GTPase 0.0015 0.008 0.0484
Brugia malayi ImpB/MucB/SamB family protein 0.0032 0.0224 0.0687
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0008 0.0022 0.0059
Giardia lamblia DNA damage repair protein 0.001 0.0039 0.0064
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0006 0.0007 0.0012
Schistosoma mansoni acetyl-CoA synthetase 0.0006 0.0007 0.0005
Schistosoma mansoni survival motor neuron protein 0.0038 0.0269 0.0319
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Toxoplasma gondii hypothetical protein 0.0009 0.0034 0.0293
Onchocerca volvulus 0.0037 0.0259 0.0784
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0022 0.0039
Onchocerca volvulus 0.0349 0.2842 0.8799
Schistosoma mansoni gabp alpha 0.008 0.0616 0.0734
Brugia malayi MH1 domain containing protein 0.001 0.0041 0.0118
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0008 0.0022 0.0018
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0037 0.0261 0.0801
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.077 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0129 0.0392
Onchocerca volvulus 0.0057 0.043 0.1313
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.077 1
Brugia malayi steroid hormone receptor 0.0008 0.0022 0.0059
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.0028 0.0025
Brugia malayi MH1 domain containing protein 0.0018 0.0109 0.0329
Plasmodium falciparum serine/threonine protein phosphatase 5 0.002 0.0118 0.1975
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0109 0.0102
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0085 0.0657 0.0778
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0009 0.0034 0.0442
Loa Loa (eye worm) hypothetical protein 0.002 0.0124 0.0377
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0015 0.008 0.024
Echinococcus multilocularis snurportin 1 0.0217 0.175 0.1744
Schistosoma mansoni cpg binding protein 0.0038 0.0273 0.0324
Echinococcus granulosus hypothetical protein 0.0041 0.0299 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0129 0.0392
Trypanosoma brucei prolyl oligopeptidase, putative 0.0009 0.0034 0.0411
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0392
Brugia malayi MH2 domain containing protein 0.027 0.2194 0.6794
Loa Loa (eye worm) hypothetical protein 0.0395 0.3229 1
Plasmodium falciparum peptidase, putative 0.0009 0.0034 0.0482
Leishmania major DNA polymerase eta, putative 0.0047 0.0346 0.4493
Trichomonas vaginalis D-aminoacylase, putative 0.0098 0.077 0.2702
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0233
Mycobacterium ulcerans lipase LipD 0.0098 0.077 0.146
Loa Loa (eye worm) hypothetical protein 0.0041 0.0299 0.0918
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0009 0.0028 0.0025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.024 0.0233
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0042 0.0306 0.0357
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0022 0.0059
Toxoplasma gondii HEAT repeat-containing protein 0.002 0.0124 0.1271
Echinococcus granulosus ewsr:fli fusion protein type 0.0012 0.0052 0.0054
Mycobacterium leprae Probable polyketide synthase Pks1 0.0019 0.011 0.0206
Echinococcus multilocularis expressed protein 0.0011 0.005 0.0043
Schistosoma mansoni hypothetical protein 0.0012 0.0052 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0052 0.0153
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0009 0.0028 0.003
Leishmania major oligopeptidase b 0.0009 0.0034 0.0442
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0052 0.0153
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0138 0.1796
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.0028 0.003
Mycobacterium ulcerans hypothetical protein 0.0021 0.0129 0.0243
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0118 0.093 0.1764
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha 0.0006 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.0145
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0009 0.0034 0.0111
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0009 0.0034 0.0442
Brugia malayi Fli-1 protein 0.0242 0.1959 0.6064
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0009 0.0028 0.0021
Leishmania major protein kinase, putative 0.0042 0.0304 0.3949
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0138 0.017
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Plasmodium vivax serine/threonine protein phosphatase 5, putative 0.002 0.0118 0.1456
Loa Loa (eye worm) hypothetical protein 0.0008 0.0021 0.0056
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0268 0.2172 0.6723
Entamoeba histolytica hypothetical protein 0.0011 0.0049 0.0293
Trypanosoma brucei oligopeptidase b 0.0009 0.0034 0.0411
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.0009 0.0029 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Schistosoma mansoni GTP-binding protein alpha subunit 0.0009 0.0028 0.003
Brugia malayi photoreceptor-specific nuclear receptor 0.0008 0.0022 0.0059
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0085 0.0657 0.0778
Brugia malayi Protein kinase domain containing protein 0.0062 0.0468 0.1444
Leishmania major hypothetical protein, conserved 0.0098 0.077 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0184 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0468 0.0557
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0138 0.085
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0141 0.1806
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.1623 0.1934
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0098 0.077 0.146
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0231 0.0224
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0009 0.0028 0.003
Brugia malayi MH2 domain containing protein 0.0018 0.0109 0.0329
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0062 0.0468 0.6084
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0008 0.0024 0.0054
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0101 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0008 0.0022 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0022 0.0018
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0109 0.0329
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0304 0.1062
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0138 0.177
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0098 0.077 0.146
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0022 0.0023
Loa Loa (eye worm) flap endonuclease-1 0.0018 0.0103 0.0311
Onchocerca volvulus 0.0036 0.0256 0.0773
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0025 0.0161 0.1669
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0138 0.0261
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.0009 0.0029 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0011 0.0049 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0049 0.0165
Loa Loa (eye worm) hypothetical protein 0.003 0.0207 0.0634
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0138 0.1796
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0119 0.0938 0.289
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.0028 0.0025
Echinococcus multilocularis dual specificity 0.0062 0.0468 0.0462
Onchocerca volvulus Prolyl endopeptidase homolog 0.0009 0.0034 0.0084
Schistosoma mansoni ap endonuclease 0.0022 0.0138 0.0162
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Mycobacterium ulcerans bacterioferritin BfrA 0.0011 0.005 0.0092
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.0009 0.0029 0.0381
Brugia malayi MH2 domain containing protein 0.0008 0.0024 0.0068
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0006 0.0007 0.0012
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Trypanosoma brucei glycerol uptake protein, putative 0.0011 0.0049 0.061
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0014 0.0071 0.0076
Loa Loa (eye worm) mbt repeat family protein 0.0028 0.0184 0.0563
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0008 0.0022 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0022 0.0023
Trypanosoma brucei DNA damage repair protein, putative 0.001 0.0039 0.0481
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0022 0.0015
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0009 0.0034 0.0442
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0098 0.077 0.0917
Brugia malayi follicle stimulating hormone receptor 0.0395 0.3225 0.999
Echinococcus multilocularis tar DNA binding protein 0.0147 0.1173 0.1167
Trypanosoma cruzi DNA damage repair protein, putative 0.001 0.0039 0.0511
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Onchocerca volvulus 0.0028 0.0184 0.055
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0006 0.0007 0.0012
Echinococcus granulosus GA binding protein alpha chain 0.008 0.0616 0.0729
Brugia malayi Ser/Thr protein phosphatase family protein 0.0008 0.0026 0.0072
Brugia malayi DNA-binding protein D-ETS-3 0.0012 0.0052 0.0153
Echinococcus multilocularis ecdysone induced protein 78C 0.0008 0.0022 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0138 0.0478
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.024 0.3057
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0062 0.0468 0.1444
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0119 0.0938 0.1119
Loa Loa (eye worm) TAR-binding protein 0.0147 0.1173 0.3628
Toxoplasma gondii t-complex protein beta subunit 0.0014 0.0071 0.069
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0119 0.0938 0.0932
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0009 0.0028 0.0079
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Mycobacterium ulcerans polyketide synthase Pks13 0.0026 0.0173 0.0327
Entamoeba histolytica G protein alpha subunit, putative 0.0009 0.0028 0.0159
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0027
Echinococcus multilocularis GA binding protein alpha chain 0.008 0.0616 0.0609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0009 0.0028 0.0089
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0009 0.0028 0.0079
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0028 0.003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0138 0.0693
Onchocerca volvulus 0.0098 0.077 0.2367
Loa Loa (eye worm) protein phosphatase 5 0.0019 0.0113 0.0342
Echinococcus multilocularis polycomb protein SCMH1 0.0028 0.0184 0.0177
Trichomonas vaginalis antibiotic synthetase, putative 0.0006 0.0007 0.0016
Leishmania major acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0018 0.0101 0.0189
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0022 0.0023
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0018 0.0101 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0008 0.0022 0.0059
Loa Loa (eye worm) hhat protein 0.0011 0.0049 0.0145
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0142 0.0434
Echinococcus granulosus dual specificity 0.0062 0.0468 0.0552
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0036 0.025 0.0474
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0569 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0022 0.0039
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0022 0.0023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0008 0.0022 0.0015
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.0028 0.0021
Onchocerca volvulus 0.0045 0.0326 0.0989
Mycobacterium tuberculosis Probable lipase LipE 0.0098 0.077 0.146
Onchocerca volvulus Fatty acid synthase homolog 0.0032 0.0218 0.0654
Trypanosoma brucei chrX additional, unordered contigs 0.001 0.0039 0.0481
Echinococcus granulosus dna polymerase eta 0.0047 0.0346 0.0405
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0008 0.0022 0.0018
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0009 0.0028 0.003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.024 0.3119
Loa Loa (eye worm) hypothetical protein 0.0268 0.2172 0.6723
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0009 0.0034 0.0197
Schistosoma mansoni Smad4 0.0008 0.0024 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0078 0.0605 0.0721
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Brugia malayi Importin beta-1 subunit 0.002 0.0124 0.0377
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0008 0.0022 0.0059
Echinococcus granulosus dual specificity protein kinase clk2 0.0042 0.0304 0.0355
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0008 0.0022 0.0059
Leishmania major acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0101 0.0191
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0014 0.0073 0.0137
Mycobacterium ulcerans hypothetical protein 0.0118 0.093 0.1764
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Entamoeba histolytica protein kinase, putative 0.0062 0.0468 0.2914
Echinococcus granulosus mothers against decapentaplegic 6 0.0008 0.0024 0.0021
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0037 0.0261 0.3388
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.043 0.0511
Schistosoma mansoni Smad4 0.0008 0.0024 0.0026
Loa Loa (eye worm) MBOAT family protein 0.0011 0.0049 0.0145
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0008 0.0022 0.0015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0024 0.0068
Trypanosoma brucei protein phosphatase 1, putative 0.0009 0.0029 0.035
Brugia malayi prolyl oligopeptidase family protein 0.0119 0.0938 0.2899
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0015 0.008 0.1038
Echinococcus multilocularis ets variant gene 4 0.0012 0.0052 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0008 0.0022 0.0059
Brugia malayi hypothetical protein 0.0084 0.0652 0.2014
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.024 0.3097
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0138 0.0421
Brugia malayi hypothetical protein 0.0074 0.0569 0.1756
Loa Loa (eye worm) hypothetical protein 0.0061 0.0463 0.1427
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0022 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0129 0.0243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0392
Echinococcus multilocularis mothers against decapentaplegic 6 0.0008 0.0024 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0008 0.0022 0.0059
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0098 0.077 0.146
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0022 0.0059
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Trichomonas vaginalis ran, putative 0.0015 0.008 0.0273
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0015 0.008 0.079
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0039 0.0481
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0022 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0006 0.0007 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0022 0.0018
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0062 0.0185
Brugia malayi Ets-domain containing protein 0.008 0.0616 0.1901
Trichomonas vaginalis protein phosphatase-1, putative 0.0012 0.0054 0.018
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0326 0.0319
Brugia malayi Pre-SET motif family protein 0.0307 0.2492 0.7718
Trichomonas vaginalis flap endonuclease-1, putative 0.0018 0.0103 0.0353
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0304 0.0361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0199 0.1601 0.5628
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0015 0.008 0.1038
Leishmania major importin beta-1 subunit, putative 0.0016 0.0092 0.1201
Mycobacterium ulcerans esterase/lipase LipP 0.0098 0.077 0.146
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0006 0.0007 0.009
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0008 0.0022 0.0039
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0037 0.0261 0.0304
Echinococcus multilocularis survival motor neuron protein 1 0.0185 0.1489 0.1483
Echinococcus granulosus flap endonuclease 1 0.0018 0.0103 0.0115
Loa Loa (eye worm) hypothetical protein 0.0057 0.043 0.1325
Loa Loa (eye worm) G protein alpha subunit 3 0.0009 0.0028 0.0079
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0009 0.0028 0.0089
Onchocerca volvulus 0.0009 0.0028 0.0065
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0199 0.1601 1
Echinococcus granulosus survival motor neuron protein 1 0.0185 0.1489 0.1774
Echinococcus granulosus sterol O acyltransferase 1 0.0115 0.0909 0.1079
Entamoeba histolytica hypothetical protein 0.0084 0.0652 0.4067
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0006 0.0007 0.009
Loa Loa (eye worm) prolyl oligopeptidase 0.0119 0.0938 0.2899
Brugia malayi RNA, U transporter 1 0.0058 0.0434 0.1338
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0036 0.025 0.3252
Echinococcus granulosus snurportin 1 0.0217 0.175 0.2086
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0138 0.1722
Entamoeba histolytica Flap nuclease, putative 0.0018 0.0103 0.0627
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0628 0.5153 0.9782
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0129 0.0392
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Echinococcus multilocularis protein C ets 2 0.0012 0.0052 0.0045
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0119 0.0938 0.1114
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0039 0.0511
Loa Loa (eye worm) Smad1 0.0018 0.0109 0.0329
Schistosoma mansoni smad1 5 8 and 0.0018 0.0109 0.0127
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0098 0.077 0.2378
Schistosoma mansoni ferritin light chain 0.0011 0.005 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0039 0.0511
Toxoplasma gondii type I fatty acid synthase, putative 0.0012 0.0059 0.0569
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0231 0.0268
Mycobacterium ulcerans polyketide synthase Pks9 0.0012 0.0052 0.0097
Brugia malayi TAR-binding protein 0.0147 0.1173 0.3628
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0042 0.0304 0.3949
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0036 0.025 0.0244
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Trypanosoma cruzi glycerol uptake protein, putative 0.0011 0.0049 0.064
Trichomonas vaginalis penicillin-binding protein, putative 0.0098 0.077 0.2702
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.1623 0.1618
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0017 0.0097 0.0182
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0018 0.0103 0.1335
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.0224 0.289
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.093 0.1764
Mycobacterium ulcerans hypothetical protein 0.001 0.0039 0.0073
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0019 0.011 0.0206
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0109
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0569 0.7394
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0014 0.0071 0.0082
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0014 0.0071 0.024
Loa Loa (eye worm) hhat protein 0.0011 0.0049 0.0145
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0085 0.0657 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0024 0.0076
Toxoplasma gondii hypothetical protein 0.0011 0.0049 0.0459
Mycobacterium ulcerans polyketide synthase 0.0019 0.011 0.0208
Brugia malayi MH2 domain containing protein 0.0018 0.0109 0.0329
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0537 0.5745
Mycobacterium tuberculosis Conserved protein 0.0098 0.077 0.146
Echinococcus granulosus ETS transcription factor Elf 5 0.0012 0.0052 0.0054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0326 0.0386
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0006 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0009 0.0028 0.0079
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0028 0.0079
Brugia malayi MBOAT family protein 0.0011 0.0049 0.0145
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0024 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0153
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0129 0.0243
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.024 0.4147
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0022 0.0039
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.0009 0.0029 0.0083
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0024 0.0068
Mycobacterium tuberculosis Conserved protein 0.0098 0.077 0.146
Leishmania major DNA polymerase eta, putative 0.0025 0.0161 0.2092
Echinococcus granulosus geminin 0.1016 0.8364 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0009 0.0034 0.0038
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0009 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.001 0.0041 0.0118
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0009 0.0028 0.0079
Schistosoma mansoni protein phosphatase-1 0.0009 0.0029 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0141 0.1806
Mycobacterium ulcerans bacterioferritin BfrB 0.0011 0.005 0.0092
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0014 0.0073 0.0137
Leishmania major GTP-binding protein, putative 0.0015 0.008 0.1038
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0052 0.0045
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0062 0.0468 0.6084
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0014 0.0071 0.0835
Loa Loa (eye worm) hypothetical protein 0.0008 0.0022 0.0059
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0092 0.0317
Echinococcus granulosus tumor protein p63 0.0391 0.3193 0.3812
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0045 0.0326 0.0319
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0084 0.0652 0.0646
Trichomonas vaginalis DNA polymerase eta, putative 0.0032 0.0224 0.0781
Schistosoma mansoni ferritin 0.0011 0.005 0.0056
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0009 0.0028 0.0089
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0009 0.0029 0.0027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0022 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0039 0.0481
Echinococcus multilocularis importin subunit beta 1 0.002 0.0124 0.0117
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0017 0.0097 0.0182
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0014 0.0073 0.0135
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.024 0.2525
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0011 0.0049 0.0056
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.0029 0.0095
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0019 0.011 0.0206
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0018 0.0103 0.1335
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0392
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.0029 0.0095
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0129 0.0243
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0019 0.011 0.0208
Loa Loa (eye worm) nuclear factor I 0.001 0.0041 0.0118
Schistosoma mansoni terminal deoxycytidyl transferase 0.0032 0.0224 0.0265
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.001 0.0039 0.0351
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0113 0.0891 0.1057
Echinococcus granulosus histone acetyltransferase MYST2 0.0031 0.0216 0.025
Schistosoma mansoni ran 0.0015 0.008 0.0093
Leishmania major glycerol uptake protein, putative 0.0011 0.0049 0.064
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0008 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0098
Echinococcus granulosus FTZ F1 alpha 0.0008 0.0022 0.0018
Giardia lamblia Alanyl dipeptidyl peptidase 0.0009 0.0034 0.003
Trichomonas vaginalis ferritin, putative 0.0011 0.005 0.0166
Trypanosoma cruzi oligopeptidase b 0.0009 0.0034 0.0442
Brugia malayi Hhat protein 0.0011 0.0049 0.0145
Echinococcus granulosus mothers against decapentaplegic 2 0.0008 0.0024 0.0021
Onchocerca volvulus Bile acid receptor homolog 0.0008 0.0022 0.0046
Loa Loa (eye worm) MBCTL1 0.0031 0.0216 0.066
Echinococcus multilocularis transcription factor Dp 1 0.0021 0.0132 0.0126
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.004 0.0286 0.372
Brugia malayi Isocitrate dehydrogenase 0.0034 0.024 0.0736
Echinococcus multilocularis Dipeptidyl peptidase 9 0.004 0.0286 0.028
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0022 0.0039
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0011 0.0049 0.0293
Schistosoma mansoni smad1 5 8 and 0.0018 0.0109 0.0127
Echinococcus granulosus Smad4 0.0018 0.0109 0.0122
Echinococcus multilocularis FTZ F1 alpha 0.0008 0.0022 0.0015
Echinococcus granulosus transcription factor Dp 1 0.0021 0.0132 0.015
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0009 0.0028 0.0079
Loa Loa (eye worm) prolyl oligopeptidase 0.0009 0.0034 0.0098
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0009 0.0028 0.0089
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0109 0.0102
Brugia malayi Ets-domain containing protein 0.0012 0.0052 0.0153
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0034 0.0442
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0032 0.0224 0.0265
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0034 0.0355
Trichomonas vaginalis esterase, putative 0.0098 0.077 0.2702
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0304 0.0361
Treponema pallidum licC protein (licC) 0.0118 0.093 0.5678
Entamoeba histolytica acyl-coA synthetase, putative 0.0021 0.0129 0.0792
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0098 0.077 0.2378
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0078 0.0147
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.1623 0.1934
Entamoeba histolytica prolyl oligopeptidase family protein 0.0009 0.0034 0.0197
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0032 0.0224 0.2912
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0031 0.0216 0.066
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0138 0.0573
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0022 0.0059
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.0009 0.0029 0.0294
Brugia malayi mbt repeat family protein 0.0028 0.0184 0.0563
Toxoplasma gondii exonuclease III APE 0.0022 0.0138 0.1422
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0018 0.0101 0.0191
Echinococcus granulosus Dipeptidyl peptidase 9 0.004 0.0286 0.0334
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0062 0.0468 0.6084
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0129 0.1676
Schistosoma mansoni protein phosphatase-7 0.0008 0.0026 0.0028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0085 0.0657 0.2029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0024 0.0076
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0016 0.0085 0.016
Entamoeba histolytica prolyl oligopeptidase family protein 0.0009 0.0034 0.0197
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0085 0.0657 0.0651
Mycobacterium ulcerans beta-lactamase 0.0098 0.077 0.146
Brugia malayi AMP-binding enzyme family protein 0.0006 0.0008 0.0017
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0011 0.0049 0.0042
Leishmania major serine/threonine protein phosphatase type 5, putative 0.002 0.0118 0.1533
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Trichomonas vaginalis transmembrane protein nessy, putative 0.0011 0.0049 0.0165
Schistosoma mansoni importin beta-1 0.002 0.0124 0.0146
Schistosoma mansoni protein phosphatase-1 0.0009 0.0029 0.0032
Mycobacterium tuberculosis Probable esterase LipL 0.0098 0.077 0.146
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0011 0.005 0.0092
Schistosoma mansoni ferritin light chain 0.0011 0.005 0.0056
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0014 0.0071 0.0064
Schistosoma mansoni smad1 5 8 and 0.0018 0.0109 0.0127
Brugia malayi Calcitonin receptor-like protein seb-1 0.0268 0.2172 0.6723
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0008 0.0022 0.0059
Brugia malayi G-protein alpha subunit 0.0009 0.0028 0.0079
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0045 0.0326 0.3452
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0022 0.0059
Schistosoma mansoni hypothetical protein 0.1016 0.8364 1
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.0009 0.0029 0.0022
Echinococcus multilocularis dna polymerase eta 0.0047 0.0346 0.0339
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0008 0.0022 0.0059
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0014 0.0071 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Echinococcus multilocularis ETS transcription factor Elf 5 0.0012 0.0052 0.0045
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0009 0.0028 0.0089
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0011 0.0049 0.0056
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0098
Onchocerca volvulus 0.0023 0.0142 0.0421
Plasmodium vivax serine/threonine kinase-1, putative 0.0042 0.0304 0.3894
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.004 0.0286 0.372
Mycobacterium ulcerans hypothetical protein 0.0098 0.077 0.146
Loa Loa (eye worm) MBOAT family protein 0.0011 0.0049 0.0145
Loa Loa (eye worm) hypothetical protein 0.0085 0.0657 0.2029
Schistosoma mansoni sterol O-acyltransferase 1 0.0115 0.0909 0.1084
Plasmodium vivax SET domain protein, putative 0.0045 0.0326 0.4178
Schistosoma mansoni coup transcription factor 0.0008 0.0022 0.0023
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0011 0.0049 0.0051
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.004 0.0286 0.3699
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0024 0.0076
Loa Loa (eye worm) hypothetical protein 0.0098 0.077 0.2378
Trichomonas vaginalis D-aminoacylase, putative 0.0098 0.077 0.2702
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0044 0.0044
Schistosoma mansoni DNA polymerase eta 0.0047 0.0346 0.0411
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0138 0.0478
Loa Loa (eye worm) fli-1 protein 0.0242 0.1959 0.6064
Brugia malayi hypothetical protein 0.0395 0.3229 1
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0019 0.011 0.0208
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0024 0.0076
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0028 0.003
Trypanosoma brucei hypothetical protein, conserved 0.0098 0.077 1
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0009 0.0028 0.0021
Echinococcus granulosus GTP binding nuclear protein Ran 0.0015 0.008 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0034 0.0442
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0144 0.0883
Onchocerca volvulus 0.0038 0.0269 0.0813
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0022 0.0023
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0016 0.0085 0.5
Trypanosoma brucei unspecified product 0.0032 0.0224 0.289
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0038 0.0269 0.0826
Schistosoma mansoni DNA polymerase IV / kappa 0.001 0.0039 0.0044
Brugia malayi RNA recognition motif domain containing protein 0.0147 0.1173 0.3628
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.025 0.0474
Giardia lamblia DINP protein human, muc B family 0.0032 0.0224 0.124
Brugia malayi prolyl oligopeptidase family protein 0.004 0.0286 0.088
Echinococcus granulosus expressed protein 0.0009 0.0028 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.0008 0.0022 0.0015
Treponema pallidum bacterioferrin (TpF1) 0.0011 0.005 0.0002
Schistosoma mansoni hypothetical protein 0.0183 0.1471 0.1756
Loa Loa (eye worm) oxidoreductase 0.0006 0.0007 0.0014
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0202 0.1623 0.5025
Schistosoma mansoni apoferritin-2 0.0011 0.005 0.0056
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0113 0.0891 0.0884
Schistosoma mansoni tar DNA-binding protein 0.0147 0.1173 0.14
Mycobacterium ulcerans fatty acid synthase Fas 0.0006 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0049 0.0165
Loa Loa (eye worm) hypothetical protein 0.0183 0.1471 0.4551
Brugia malayi Flap endonuclease-1 0.0018 0.0103 0.0311
Brugia malayi transcription factor E74 isoform 0.0012 0.0052 0.0153
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0147 0.1173 0.3628
Toxoplasma gondii aldehyde dehydrogenase 0.0036 0.025 0.2636
Mycobacterium ulcerans DNA polymerase IV 0.0032 0.0224 0.0424
Mycobacterium tuberculosis Probable thioesterase TesA 0.0015 0.0077 0.0145
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0138 0.0157
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0268 0.2172 0.6723
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0153
Schistosoma mansoni protein phosphatase-5 0.0021 0.0127 0.0148
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0015 0.008 0.0956
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0052 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0224 0.289
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0009 0.0028 0.0079
Trypanosoma cruzi GUP1, putative 0.0011 0.0049 0.064
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0009 0.0034 0.0061
Leishmania major protein kinase, putative 0.0042 0.0304 0.3949
Trypanosoma cruzi DNA polymerase kappa, putative 0.0032 0.0224 0.2912
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0326 0.0386
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0138 0.0421
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0642 0.5267 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0011 0.005 0.0092
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0008 0.0022 0.0018
Echinococcus granulosus GPCR family 2 0.0085 0.0657 0.0778
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0013 0.006 0.0113
Schistosoma mansoni hypothetical protein 0.0085 0.0657 0.0783
Loa Loa (eye worm) hypothetical protein 0.0016 0.0085 0.0257
Mycobacterium leprae conserved hypothetical protein 0.0098 0.077 0.1458
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0022 0.0023
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0019 0.011 0.0208
Brugia malayi CXXC zinc finger family protein 0.0036 0.0256 0.0785
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0042 0.0304 0.393
Loa Loa (eye worm) hypothetical protein 0.0009 0.0029 0.0083
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0019 0.011 0.0208
Schistosoma mansoni protein phosphatase type 1 0.0009 0.0029 0.0032
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0217 0.175 0.5416
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0011 0.0049 0.0042
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0109 0.0329
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0006 0.0007 0.0012
Brugia malayi mothers against decapentaplegic homolog 3 0.0008 0.0024 0.0068
Schistosoma mansoni transcription factor LCR-F1 0.0084 0.0652 0.0777
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0124 0.1587
Brugia malayi ecdysteroid receptor 0.0008 0.0022 0.0059
Trichomonas vaginalis importin beta-1, putative 0.0016 0.0092 0.0317
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.004 0.0286 0.3699
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0098
Echinococcus granulosus smad 0.0018 0.0109 0.0122
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0036 0.025 0.0291
Brugia malayi hypothetical protein 0.003 0.0208 0.0638
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0006 0.0007 0.0012
Brugia malayi mbt repeat family protein 0.0028 0.0184 0.0563
Brugia malayi Ets-domain containing protein 0.008 0.0616 0.1901
Loa Loa (eye worm) acyl carrier protein 0.0008 0.0023 0.0063
Plasmodium falciparum protein serine/threonine kinase-1 0.0042 0.0304 0.5284
Echinococcus granulosus acylamino acid releasing enzyme 0.0009 0.0034 0.0032

Activities

Activity type Activity value Assay description Source Reference
IZ (functional) = 0.04 millimeter Antimicrobial activity against Escherichia coli at 1 umol/disk after 24 hrs by disk diffusion assay ChEMBL. 19926364
IZ (functional) = 7 millimeter Antimicrobial activity against Escherichia coli at 10 ug/disk after 24 hrs by disk diffusion assay ChEMBL. 19926364
MBC (functional) = 34.6 10'-2micromol/ml Antimicrobial activity against Escherichia coli after 24 hrs by microdilution technique ChEMBL. 19926364
MIC (functional) = 17.3 10'-2micromol/ml Antimicrobial activity against Escherichia coli after 24 hrs by microdilution technique ChEMBL. 19926364

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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