Detailed information for compound 1133287

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 373.426 | Formula: C18H19N3O4S
  • H donors: 3 H acceptors: 5 LogP: 1.86 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1ccc2c1ncnc2SC1C=CC=CC=C1
  • InChi: 1S/C18H19N3O4S/c22-9-13-14(23)15(24)18(25-13)21-8-7-12-16(21)19-10-20-17(12)26-11-5-3-1-2-4-6-11/h1-8,10-11,13-15,18,22-24H,9H2/t13-,14-,15-,18?/m1/s1
  • InChiKey: KDRGLBRIXDISBC-JFURGGKOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0036 0.0024 0.0369
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0017 0 0.0000029048
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0035 0.0022 0.0347
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.001
Plasmodium falciparum plasmepsin VII 0.0036 0.0024 0.0385
Brugia malayi neuroendocrine convertase 1 precursor 0.5112 0.6316 0.6316
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0041 0.003 0.0701
Brugia malayi Protein kinase domain containing protein 0.0035 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0005 0.0005
Leishmania major protein kinase, putative 0.003 0.0016 0.0058
Echinococcus granulosus protein kinase C gamma type 0.0022 0.0006 0.0006
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0102 0.0106 0.1204
Mycobacterium tuberculosis Probable thioesterase TesA 0.0045 0.0035 0.0829
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0011 0.0072
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0694 0.0839 1
Toxoplasma gondii subtilisin SUB11 0.0357 0.0422 0.9568
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0107 0.0111 0.0111
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0005 0.0006
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Brugia malayi Kelch motif family protein 0.0138 0.015 0.015
Plasmodium vivax thrombospondin-related anonymous protein 0.0023 0.0008 0.0053
Echinococcus multilocularis glycoprotein Antigen 5 0.0024 0.0009 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0053 0.1052
Plasmodium vivax hypothetical protein, conserved 0.01 0.0103 0.203
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0005 0.0006
Loa Loa (eye worm) TK/EGFR protein kinase 0.067 0.081 0.081
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1975 0.2427 0.3969
Onchocerca volvulus Putative cubilin 0.0045 0.0035 0.0548
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0036 0.0036
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0357 0.0422 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.003 0.0016 0.019
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0694 0.0839 0.1368
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0053 0.0053
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0102 0.0106 0.0106
Echinococcus multilocularis fibrillin 1 0.0026 0.0011 0.0013
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0107 0.0111 0.1267
Schistosoma mansoni protein kinase 0.0244 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0008 0.0045
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0102 0.0106 0.0106
Echinococcus granulosus Protein kinase C brain isozyme 0.0028 0.0014 0.0014
Onchocerca volvulus 0.0191 0.0216 0.337
Echinococcus granulosus furin 0.8084 1 1
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1283 0.1569 0.1569
Schistosoma mansoni chromatin regulatory protein sir2 0.0694 0.0839 0.0839
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0036 0.0024 0.0369
Plasmodium falciparum plasmepsin IV 0.0036 0.0024 0.0385
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0035 0.0023 0.0337
Brugia malayi Protein kinase domain containing protein 0.0053 0.0045 0.0045
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0357 0.0422 1
Schistosoma mansoni discoidin domain receptor 0.0053 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0008
Brugia malayi ADAM-TS Spacer 1 family protein 0.0025 0.001 0.001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.004 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0035 0.0022 0.0132
Leishmania major phosphopantetheinyl transferase-like protein 0.0047 0.0037 0.0308
Loa Loa (eye worm) fatty acid synthase 0.0054 0.0045 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0016 0.0022
Echinococcus multilocularis growth factor receptor bound protein 2 0.0267 0.031 0.0388
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0001 0.0001
Mycobacterium ulcerans chitinase/cellulase 0.0064 0.0058 0.137
Onchocerca volvulus 0.0035 0.0023 0.0353
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus granulosus serine:threonine protein kinase N2 0.002 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0053 0.0053
Entamoeba histolytica chitinase, putative 0.0075 0.0071 0.0806
Onchocerca volvulus 0.0534 0.0641 1
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0053 0.0045 0.0056
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus granulosus NCK adaptor protein 0.0021 0.0005 0.0005
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0011 0.0125
Echinococcus granulosus intermediate filament protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0146 0.016 0.016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Echinococcus multilocularis cubilin 0.0035 0.0023 0.0028
Echinococcus multilocularis protein kinase c iota type 0.0027 0.0012 0.0015
Onchocerca volvulus 0.0018 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0052 0.0043 0.1013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0042 0.003 0.0038
Plasmodium falciparum calcium-dependent protein kinase 5 0.003 0.0016 0.0225
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.003 0.0016 0.0225
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0136 0.0136
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0035 0.0023 0.0023
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0008 0.0045
Loa Loa (eye worm) thioredoxin reductase 0.0076 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0296 0.0346 0.0345
Echinococcus multilocularis discoidin domain containing receptor 2 0.0053 0.0045 0.0056
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0019 0.0019
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0011 0.0271
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0023 0.0008 0.0008
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Brugia malayi Protein kinase domain containing protein 0.0043 0.0032 0.0032
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0357 0.0422 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0017 0.0016
Plasmodium falciparum LCCL domain-containing protein 0.0053 0.0045 0.0824
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.003 0.0016 0.019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0043 0.0033 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0189 0.0213 0.0267
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0233 0.0268 0.0268
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0107 0.0111 0.2381
Treponema pallidum NADH oxidase 0.0026 0.0011 0.1197
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0024
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0357 0.0422 0.0422
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0016 0.002
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0136 0.0136
Echinococcus granulosus growth factor receptor bound protein 2 0.0267 0.031 0.031
Brugia malayi amine oxidase, flavin-containing family protein 0.0142 0.0155 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Plasmodium falciparum calcium-dependent protein kinase 2 0.003 0.0016 0.0225
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0107 0.0111 0.1267
Echinococcus granulosus integrin beta 2 0.0489 0.0586 0.0585
Echinococcus granulosus MAM 0.01 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0033 0.002 0.0473
Brugia malayi hypothetical protein 0.0296 0.0346 0.0345
Plasmodium vivax aspartyl protease, putative 0.0036 0.0024 0.0385
Loa Loa (eye worm) SRC-1 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0013
Plasmodium falciparum plasmepsin III 0.0036 0.0024 0.0385
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0107 0.0111 0.0177
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0022 0.0006 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0047 0.0037 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0694 0.0839 0.0839
Loa Loa (eye worm) RNA binding protein 0.0127 0.0136 0.0136
Brugia malayi Tyrosine-protein kinase abl-1 0.0021 0.0005 0.0005
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.0035 0.0023 0.0028
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0012 0.0012
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0041 0.003 0.0701
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0186 0.021 0.3273
Echinococcus multilocularis transmembrane protease serine 3 0.0024 0.0009 0.0011
Toxoplasma gondii F5/8 type C domain-containing protein 0.0053 0.0045 0.0856
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0055 0.0047 0.1112
Loa Loa (eye worm) Carm1-pending protein 0.0107 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0004 0.0004
Mycobacterium ulcerans Sir2-like regulatory protein 0.0102 0.0106 0.2506
Onchocerca volvulus 0.0478 0.0571 0.8911
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0023 0.0008 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.003 0.0045
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0001 0.0008
Echinococcus granulosus tissue type plasminogen activator 0.0035 0.0022 0.0022
Mycobacterium ulcerans Type I modular polyketide synthase 0.0052 0.0043 0.1013
Echinococcus granulosus protein arginine methyltransferase 0.0189 0.0213 0.0213
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0053 0.0045 0.1067
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0019 0.0023
Echinococcus multilocularis tissue type plasminogen activator 0.0035 0.0022 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Schistosoma mansoni hypothetical protein 0.0053 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0053 0.0045 0.0045
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Chlamydia trachomatis protoporphyrinogen oxidase 0.01 0.0103 1
Echinococcus multilocularis serotonin receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) DEAH box polypeptide 35 0.0034 0.0021 0.002
Echinococcus granulosus membrane bound transcription factor site 1 0.0357 0.0422 0.0422
Echinococcus granulosus adam 17 protease 0.0018 0.0001 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0011 0.0125
Brugia malayi Integrin beta pat-3 precursor 0.0665 0.0803 0.0803
Onchocerca volvulus 0.0035 0.0023 0.0353
Onchocerca volvulus 0.002 0.0004 0.0062
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0011 0.0014
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0107 0.0111 0.0111
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1975 0.2427 0.3969
Loa Loa (eye worm) hypothetical protein 0.0186 0.021 0.021
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0024 0.0009 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0005 0.0006
Onchocerca volvulus 0.0018 0.0001 0.0008
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0055 0.0047 0.1112
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Echinococcus granulosus C type lectin domian containing protein 0.0041 0.0029 0.0029
Brugia malayi Nematode astacin protease protein 30 0.0035 0.0023 0.0023
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0045 0.0035 0.0829
Onchocerca volvulus Putative endochitinase 0.0075 0.0071 0.1113
Echinococcus granulosus methyltransferase protein 5 0.0107 0.0111 0.0111
Schistosoma mansoni tyrosine kinase 0.0021 0.0005 0.0005
Toxoplasma gondii rhoptry neck protein RON1 0.0041 0.0029 0.0488
Schistosoma mansoni intermediate filament proteins 0.0027 0.0012 0.0012
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0005 0.0005
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0011 0.0271
Echinococcus multilocularis Glutaredoxin protein 5 0.0021 0.0005 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0011 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0036 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Onchocerca volvulus 0.0018 0.0001 0.0008
Toxoplasma gondii aspartyl protease ASP3 0.0036 0.0024 0.0369
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.01 0.0103 0.0103
Plasmodium falciparum calcium-dependent protein kinase 1 0.003 0.0016 0.0225
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Toxoplasma gondii aspartyl protease ASP1 0.0036 0.0024 0.0369
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0022 0.0203
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0053 0.0053
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0047 0.0037 0.279
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0057 0.0057
Onchocerca volvulus 0.0018 0.0001 0.0008
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0267 0.031 0.031
Brugia malayi Angiotensin-converting enzyme family protein 0.1917 0.2355 0.2355
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis Furin 1 0.1975 0.2427 0.3036
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0053 0.0053
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0138 0.015 0.015
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0009
Plasmodium falciparum plasmepsin IX 0.0036 0.0024 0.0385
Plasmodium falciparum plasmepsin V 0.0409 0.0486 1
Onchocerca volvulus 0.0018 0.0001 0.0008
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Echinococcus granulosus serine:threonine protein kinase N2 0.0075 0.0072 0.0072
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0244 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Schistosoma mansoni site-1 peptidase (S08 family) 0.0357 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.007 0.0065 0.0065
Echinococcus multilocularis discoidin domain containing receptor 2 0.0053 0.0045 0.0056
Brugia malayi aspartic protease BmAsp-2, identical 0.0036 0.0024 0.0024
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0021 0.0005 0.0005
Toxoplasma gondii rhoptry neck protein RON9 0.0041 0.0029 0.0488
Echinococcus multilocularis enteropeptidase 0.0024 0.0009 0.0011
Schistosoma mansoni atypical protein kinase C 0.0027 0.0012 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0053 0.1254
Mycobacterium tuberculosis Possible oxidoreductase 0.01 0.0103 0.2438
Mycobacterium ulcerans hypothetical protein 0.0024 0.0009 0.0213
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0694 0.0839 1
Brugia malayi Variant SH3 domain containing protein 0.0017 0 0.0000029048
Echinococcus multilocularis protein kinase c epsilon type 0.0103 0.0106 0.0132
Brugia malayi GCC2 and GCC3 family protein 0.0051 0.0042 0.0041
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0102 0.0106 0.114
Echinococcus granulosus CUB 0.0035 0.0023 0.0023
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0357 0.0422 0.0422
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0023 0.0008 0.0053
Plasmodium falciparum cysteine repeat modular protein 1 0.0035 0.0022 0.0353
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0001 0.0001
Toxoplasma gondii PA14 domain-containing protein 0.0053 0.0045 0.0856
Trypanosoma brucei hypothetical protein, conserved 0.0047 0.0037 0.0308
Echinococcus granulosus Mastin 0.0024 0.0009 0.0009
Brugia malayi angiogenesis inhibito 0.0025 0.001 0.001
Onchocerca volvulus 0.0041 0.0029 0.0452
Mycobacterium ulcerans polyketide synthase 0.0055 0.0047 0.1112
Onchocerca volvulus 0.0095 0.0096 0.1497
Plasmodium falciparum plasmepsin VI 0.0036 0.0024 0.0385
Trichomonas vaginalis AGC family protein kinase 0.002 0.0004 0.0002
Mycobacterium ulcerans oxidoreductase 0.01 0.0103 0.2438
Onchocerca volvulus 0.0023 0.0008 0.0122
Brugia malayi hypothetical protein 0.0036 0.0024 0.0024
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.4947 0.6111 0.6111
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0078 0.0076 0.1803
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0001 0.0001
Echinococcus multilocularis NCK adaptor protein 0.0021 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0041 0.003 0.0701
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1917 0.2355 0.2355
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0189 0.0213 0.4749
Plasmodium vivax calcium-dependent protein kinase, putative 0.003 0.0016 0.0225
Echinococcus granulosus discoidin domain containing receptor 2 0.0053 0.0045 0.0045
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0052 0.0043 0.0043
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0102 0.0106 0.0274
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.0003 0.0003
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0036 0.0024 0.003
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0492 0.0589 0.0737
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0036 0.0036
Brugia malayi Thioredoxin reductase 0.0076 0.0073 0.0073
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0694 0.0839 0.0839
Schistosoma mansoni hypothetical protein 0.0032 0.0019 0.0019
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0011 0.0125
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0357 0.0422 0.0528
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0173 0.0193 0.4581
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Echinococcus multilocularis 0.6466 0.7995 1
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0192 0.0217 0.5149
Onchocerca volvulus 0.0023 0.0008 0.0122
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0102 0.0106 0.0132
Schistosoma mansoni amine oxidase 0.01 0.0103 0.0103
Brugia malayi Endochitinase 0.0075 0.0071 0.0071
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0021 0.0005 0.0005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.003 0.0016 0.0016
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0296 0.0346 0.4081
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0011 0.0271
Plasmodium falciparum apical sushi protein 0.0041 0.0029 0.0492
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0023 0.0008 0.0053
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.0041
Leishmania major arginine N-methyltransferase, type I 0.0107 0.0111 0.1203
Echinococcus granulosus Furin 1 0.1975 0.2427 0.2427
Echinococcus granulosus protein kinase c epsilon type 0.0103 0.0106 0.0106
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1975 0.2427 0.3969
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.01 0.0103 0.2438
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0103 0.0106 0.0106
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.01 0.0103 0.203
Echinococcus granulosus protein will die slowly 0.0275 0.032 0.032
Trypanosoma cruzi trypanothione reductase, putative 0.0076 0.0073 0.0809
Brugia malayi pregnancy-associated plasma protein-A 0.0041 0.0029 0.0029
Onchocerca volvulus 0.01 0.0103 0.1601
Mycobacterium ulcerans polyketide synthase 0.0052 0.0043 0.1013
Schistosoma mansoni dihydroceramide desaturase 0.0018 0.0001 0.0001
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0011 0.0014
Schistosoma mansoni serine/threonine kinase 0.002 0.0004 0.0004
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0001 0.0008
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0052 0.0043 0.1013
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.1618 0.1984 0.3243
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1975 0.2427 0.3969
Echinococcus granulosus neuroendocrine convertase 2 0.5112 0.6316 0.6316
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0055 0.0047 0.1112
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0011 0.0072
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.003 0.0016 0.0225
Loa Loa (eye worm) transcriptional regulator 0.0102 0.0106 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0136 0.0136
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0047 0.0037 0.067
Loa Loa (eye worm) DPY-31 protein 0.0035 0.0023 0.0023
Brugia malayi hypothetical protein 0.01 0.0103 0.0103
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.4947 0.6111 1
Onchocerca volvulus 0.0023 0.0008 0.0122
Brugia malayi Pre-SET motif family protein 0.006 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0173 0.0193 0.4581
Brugia malayi hypothetical protein 0.0023 0.0008 0.0008
Echinococcus granulosus thioredoxin glutathione reductase 0.0077 0.0074 0.0074
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0011 0.0072
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0051 0.0042 0.0042
Echinococcus multilocularis MAM 0.01 0.0103 0.0128
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0694 0.0839 0.1368
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0078 0.0076 0.1803
Echinococcus multilocularis serine threonine protein kinase 0.0022 0.0006 0.0007
Leishmania major trypanothione reductase 0.0076 0.0073 0.0743
Brugia malayi Furin-like cysteine rich region family protein 0.067 0.081 0.081
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0049 0.0039 0.0039
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0024 0.0009 0.0009
Onchocerca volvulus 0.002 0.0004 0.0062
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0024 0.0009 0.0009
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0047 0.0037 0.0876
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Toxoplasma gondii subtilisin SUB2 0.0357 0.0422 0.9568
Brugia malayi SEA domain containing protein 0.002 0.0004 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0005 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0077 0.0074 0.0093
Trichomonas vaginalis AGC family protein kinase 0.002 0.0004 0.0002
Loa Loa (eye worm) CUTiclin-Like family member 0.0023 0.0008 0.0008
Plasmodium vivax subtilisin-like protease 2, putative 0.0357 0.0422 0.8673
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus multilocularis GPCR, family 2 0.0032 0.0019 0.0023
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Toxoplasma gondii subtilisin SUB5 0.0357 0.0422 0.9568
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0422 0.0686
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.003 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0042 0.003 0.0315
Plasmodium vivax thioredoxin reductase, putative 0.0076 0.0073 0.1404
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0036 0.0045
Brugia malayi Probable ATP-dependent helicase DHX35 0.0034 0.0021 0.002
Schistosoma mansoni nck2/grb4 0.0021 0.0005 0.0005
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0035 0.0023 0.0023
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0357 0.0422 0.4998
Onchocerca volvulus 0.0023 0.0008 0.0122
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0105 0.0105
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0053 0.0045 0.0069
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0036 0.0024 0.0024
Brugia malayi Pre-SET motif family protein 0.042 0.0499 0.0499
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0037 0.0876
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0047 0.0037 0.0876
Leishmania major chitinase 0.0075 0.0071 0.0725
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Entamoeba histolytica protein kinase, putative 0.003 0.0016 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein kinase N2 0.0095 0.0096 0.012
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0023 0.0008 0.003
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0015 0.0015
Mycobacterium tuberculosis Possible chitinase 0.0064 0.0058 0.137
Loa Loa (eye worm) TK/ALK protein kinase 0.01 0.0103 0.0103
Echinococcus granulosus protein kinase c iota type 0.0027 0.0012 0.0012
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0021 0.0005 0.0007
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0023 0.0008 0.0053
Echinococcus granulosus discoidin domain containing receptor 2 0.0053 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0009
Brugia malayi Protein arginine N-methyltransferase 0.0107 0.0111 0.0111
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0173 0.0193 0.4581
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0047 0.0037 0.0657
Toxoplasma gondii subtilisin SUB4 0.0357 0.0422 0.9568
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Schistosoma mansoni discoidin domain receptor 0.0053 0.0045 0.0045
Trypanosoma brucei rac serine-threonine kinase, putative 0.0043 0.0032 0.0249
Mycobacterium ulcerans polyketide synthase Pks13 0.0078 0.0076 0.1803
Plasmodium falciparum thioredoxin reductase 0.0026 0.0011 0.0125
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0189 0.0213 0.0213
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.002 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0035 0.0022 0.0022
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.003 0.0016 0.0016
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0047 0.0037 0.067
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Onchocerca volvulus 0.0041 0.0029 0.0452
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0021 0.0005 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Entamoeba histolytica elongation factor-2 kinase, putative 0.0023 0.0008 0.0045
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0107 0.0111 0.1203
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0107 0.0111 0.0139
Toxoplasma gondii F5/8 type C domain-containing protein 0.0053 0.0045 0.0856
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0107 0.0111 0.0177
Loa Loa (eye worm) TK/ROR protein kinase 0.0035 0.0022 0.0022
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0492 0.0589 0.0589
Schistosoma mansoni hypothetical protein 0.01 0.0103 0.0103
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0036 0.0024 0.0034
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0049 0.0039 0.0039
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.002 0.0004 0.0004
Plasmodium falciparum plasmepsin II 0.0036 0.0024 0.0385
Trypanosoma cruzi UDP-galactopyranose mutase 0.01 0.0103 0.117
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.8084 1 1
Leishmania major silent information regulator 2, putative 0.0694 0.0839 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0052 0.0043 0.1013
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0028 0.0014 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0011 0.0125
Brugia malayi RhoGAP domain containing protein 0.0017 0 0.0000029048
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Onchocerca volvulus 0.0018 0.0001 0.0008
Schistosoma mansoni lamin 0.0027 0.0012 0.0012
Echinococcus multilocularis tar DNA binding protein 0.0127 0.0136 0.017
Echinococcus granulosus Tolloid protein 1 0.0049 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0008 0.0045
Brugia malayi SWIRM domain containing protein 0.0534 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.01 0.0103 0.0103
Schistosoma mansoni c4b-binding protein beta chain 0.0041 0.0029 0.0029
Onchocerca volvulus 0.0023 0.0008 0.0122
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0011 0.008
Mycobacterium ulcerans chitinase/cellulase 0.0064 0.0058 0.137
Brugia malayi CUB domain containing protein 0.0035 0.0023 0.0023
Brugia malayi Trypsin-like protease protein 5 0.0024 0.0009 0.0009
Onchocerca volvulus 0.0018 0.0001 0.0008
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0016 0.0016
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0694 0.0839 1
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.1618 0.1984 0.3243
Echinococcus granulosus serine/threonine protein kinase 0.0023 0.0008 0.0008
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0011 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Echinococcus granulosus tyrosine protein kinase Lyn 0.0022 0.0006 0.0006
Echinococcus granulosus lamin dm0 0.0027 0.0012 0.0012
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.0011 0.0016
Brugia malayi celfurPC protein 0.6466 0.7995 0.7995
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.0016
Plasmodium falciparum subtilisin-like protease 3 0.0357 0.0422 0.8673
Loa Loa (eye worm) DOMON domain-containing protein 0.002 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.0103
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0189 0.0213 0.4331
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.0103
Mycobacterium ulcerans Type I modular polyketide synthase 0.0052 0.0043 0.1013
Toxoplasma gondii thioredoxin reductase 0.0076 0.0073 0.15
Trichomonas vaginalis AGC family protein kinase 0.002 0.0004 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0014 0.0014
Onchocerca volvulus 0.0018 0.0001 0.0008
Toxoplasma gondii histone deacetylase SIR2-like 0.0102 0.0106 0.2259
Leishmania major arginine N-methyltransferase-like protein 0.0189 0.0213 0.2441
Entamoeba histolytica PH domain containing protein kinase, putative 0.0077 0.0075 0.0846
Brugia malayi SWIRM domain containing protein 0.0042 0.003 0.003
Plasmodium vivax plasmepsin IV, putative 0.0036 0.0024 0.0385
Brugia malayi Pepsin A precursor 0.0036 0.0024 0.0024
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0023 0.0008 0.0053
Loa Loa (eye worm) hypothetical protein 0.0534 0.0641 0.0641
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0001 0.0001
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0036 0.0024 0.0024
Brugia malayi von Willebrand Factor 0.0023 0.0008 0.0008
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0102 0.0106 0.0132
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0055 0.0047 0.1112
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Echinococcus granulosus Glutaredoxin protein 5 0.0021 0.0005 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0053 0.0053
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0047 0.0037 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.007 0.0065 0.0065
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0012 0.0012
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0005 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0053 0.1254
Entamoeba histolytica protein kinase, putative 0.0043 0.0032 0.0333
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Toxoplasma gondii histone lysine-specific demethylase 0.01 0.0103 0.2194
Echinococcus multilocularis protein will die slowly 0.0275 0.032 0.04
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Echinococcus granulosus protein arginine N methyltransferase 7 0.0107 0.0111 0.0111
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0047 0.0037 0.0657
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0296 0.0346 0.409
Brugia malayi SRC-1 0.0021 0.0005 0.0005
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0019 0.0019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0019 0.0019
Plasmodium falciparum subtilisin-like protease 2 0.0357 0.0422 0.8673
Plasmodium falciparum thrombospondin-related anonymous protein 0.0023 0.0008 0.0053
Onchocerca volvulus 0.002 0.0004 0.0062
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0173 0.0193 0.4581
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0011 0.0271
Echinococcus multilocularis Mastin 0.0024 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0032
Schistosoma mansoni tyrosine kinase 0.067 0.081 0.0809
Echinococcus granulosus NDR protein kinase 0.002 0.0004 0.0004
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0001 0.0001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Trypanosoma brucei trypanothione reductase 0.0076 0.0073 0.0743
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0053 0.0053
Echinococcus granulosus neuropilin nrp and tolloid tll 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0167 0.0185 0.0185
Echinococcus multilocularis lamin dm0 0.0027 0.0012 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Schistosoma mansoni growth factor receptor-bound protein 0.0267 0.031 0.031
Schistosoma mansoni protein kinase 0.0244 0.0282 0.0282
Echinococcus multilocularis serine:threonine protein kinase N2 0.002 0.0004 0.0005
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0798 0.0968 0.1211
Echinococcus granulosus c4b binding protein beta chain 0.0041 0.0029 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0011 0.0072
Brugia malayi ADAMTS-like protease 0.0025 0.001 0.001
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0357 0.0422 0.0422
Brugia malayi intermediate filament protein 0.0027 0.0012 0.0012
Plasmodium vivax apical sushi protein, putative 0.0041 0.0029 0.0492
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.003 0.0016 0.019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1975 0.2427 0.3969
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0043 0.0033 0.0032
Onchocerca volvulus 0.0018 0.0001 0.0008
Echinococcus multilocularis rac serine:threonine kinase 0.0023 0.0008 0.001
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0296 0.0346 0.4081
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0102 0.0106 0.2088
Loa Loa (eye worm) cuticular endochitinase 0.0075 0.0071 0.0071
Echinococcus multilocularis L aminoadipate semialdehyde 0.0167 0.0185 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0023 0.0032
Onchocerca volvulus 0.0149 0.0163 0.2545
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Brugia malayi Will die slowly protein 0.0275 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.3137 0.3868 0.3868
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0102 0.0106 0.1217
Brugia malayi hypothetical protein 0.01 0.0103 0.0103
Onchocerca volvulus 0.0036 0.0024 0.0371
Brugia malayi Nematode astacin protease protein 30 0.0035 0.0023 0.0023
Echinococcus granulosus lysine specific histone demethylase 1A 0.0492 0.0589 0.0589
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0023 0.0008 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.006 0.0053 0.0053
Loa Loa (eye worm) trypsin family protein 0.0024 0.0009 0.0009
Toxoplasma gondii kringle domain-containing protein 0.0035 0.0022 0.0333
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0045
Entamoeba histolytica hypothetical protein, conserved 0.0102 0.0106 0.1217
Loa Loa (eye worm) hypothetical protein 0.0357 0.0422 0.0422
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0053 0.0502
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0167 0.0185 0.0185
Echinococcus multilocularis protein arginine methyltransferase 0.0189 0.0213 0.0267
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0136 0.0136
Brugia malayi Hr1 repeat family protein 0.002 0.0004 0.0004
Echinococcus multilocularis c4b binding protein beta chain 0.0041 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0053 0.0045 0.0069
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.01 0.0103 0.2194
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.01 0.0103 0.203
Echinococcus multilocularis musashi 0.0027 0.0012 0.0015
Onchocerca volvulus 0.0024 0.0009 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Schistosoma mansoni tyrosine kinase 0.0021 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0005 0.0006
Schistosoma mansoni chromatin regulatory protein sir2 0.0102 0.0106 0.0106
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Giardia lamblia Sirtuin type 2 0.0102 0.0106 0.0274
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0001 0.0001
Brugia malayi aspartic protease BmAsp-1, identical 0.0036 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0275 0.032 0.032
Onchocerca volvulus Putative endochitinase 0.0075 0.0071 0.1113
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Loa Loa (eye worm) hypothetical protein 0.0149 0.0163 0.0163
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0005 0.0005
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Echinococcus granulosus voltage dependent calcium channel subunit 0.0023 0.0008 0.0008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.042 0.0499 0.0499
Plasmodium falciparum protoporphyrinogen oxidase 0.01 0.0103 0.203
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0041 0.0029 0.0029
Brugia malayi hypothetical protein 0.0035 0.0023 0.0023
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0357 0.0422 1
Echinococcus multilocularis 0.01 0.0103 0.0129
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0019
Onchocerca volvulus 0.0041 0.0029 0.0452
Plasmodium vivax aspartyl proteinase, putative 0.0036 0.0024 0.0385
Toxoplasma gondii subtilisin SUB10 0.0357 0.0422 0.9568
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0053 0.1254
Echinococcus granulosus lamin 0.0027 0.0012 0.0012
Giardia lamblia Furin precursor putative serine protease 0.1618 0.1984 0.541
Onchocerca volvulus 0.0018 0.0001 0.0008
Onchocerca volvulus 0.0036 0.0024 0.0371
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0107 0.0111 0.1267
Brugia malayi Protein kinase domain containing protein 0.01 0.0103 0.0103
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.1618 0.1984 0.3243
Schistosoma mansoni hypothetical protein 0.0032 0.0019 0.0019
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0008 0.0045
Brugia malayi Reprolysin 0.0025 0.001 0.001
Brugia malayi proprotein convertase 2 0.5112 0.6316 0.6316
Brugia malayi astacin protease protein 30 0.0035 0.0023 0.0023
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.002 0.0004 0.0004
Brugia malayi hypothetical protein 0.0057 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Giardia lamblia hypothetical protein 0.0042 0.003 0.0069
Loa Loa (eye worm) transcriptional regulator 0.0694 0.0839 0.0839
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0051 0.0042 0.099
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0016 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0065 0.0065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Echinococcus granulosus discoidin domain containing receptor 2 0.0053 0.0045 0.0045
Echinococcus granulosus epidermal growth factor receptor 0.067 0.081 0.0809
Echinococcus granulosus L aminoadipate semialdehyde 0.0167 0.0185 0.0185
Loa Loa (eye worm) integrin beta-2 0.0665 0.0803 0.0803
Entamoeba histolytica hypothetical protein 0.0047 0.0037 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Onchocerca volvulus 0.0027 0.0012 0.0182
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0189 0.0213 0.0345
Echinococcus multilocularis sex peptide receptor 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0041 0.0029 0.0452
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.0103
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0042 0.003 0.0722
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0102 0.0106 0.0106
Plasmodium vivax NAD-dependent deacetylase, putative 0.0102 0.0106 0.2088
Echinococcus granulosus adam 0.0067 0.0061 0.0061
Brugia malayi CUB domain containing protein 0.0035 0.0023 0.0023
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.002 0.0004 0.0004
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0173 0.0193 0.4581
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0001 0.0001
Plasmodium falciparum calcium-dependent protein kinase 4 0.003 0.0016 0.0225
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0053 0.0045 0.0069
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0102 0.0106 0.2506
Schistosoma mansoni hypothetical protein 0.0032 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0053 0.0053
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0357 0.0422 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Plasmodium vivax LCCL domain-containing protein 0.0053 0.0045 0.0824
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0214 0.0244 0.0244
Loa Loa (eye worm) hypothetical protein 0.0492 0.0589 0.0589
Giardia lamblia High cysteine membrane protein Group 2 0.2972 0.3663 1
Plasmodium falciparum thioredoxin reductase 0.0076 0.0073 0.1404
Brugia malayi transcriptional regulator, Sir2 family protein 0.0102 0.0106 0.0106
Echinococcus multilocularis lamin 0.0027 0.0012 0.0015
Onchocerca volvulus 0.0018 0.0001 0.0008
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0107 0.0111 0.1203
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0694 0.0839 0.1049
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0001 0.0001
Giardia lamblia Transcriptional regulator, Sir2 family 0.0102 0.0106 0.0274
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0338 0.0398 0.0398
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0053 0.0045 0.0701
Leishmania major subtilisin-like serine peptidase 0.0357 0.0422 0.4962
Schistosoma mansoni chromatin regulatory protein sir2 0.0102 0.0106 0.0106
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.002 0.0004 0.0005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0053 0.0067
Echinococcus multilocularis tyrosine protein kinase Abl 0.0021 0.0005 0.0006
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Schistosoma mansoni site-1 peptidase (S08 family) 0.0357 0.0422 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0105
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Echinococcus multilocularis nervana 2 0.002 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0004 0.0004
Onchocerca volvulus 0.0035 0.0023 0.0353
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0001 0.0001
Echinococcus granulosus nervana 2 0.002 0.0004 0.0004
Toxoplasma gondii subtilisin SUB12 0.0357 0.0422 0.9568
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0001 0.0001
Echinococcus multilocularis epidermal growth factor receptor 0.067 0.081 0.1013
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0051 0.0051
Echinococcus multilocularis membrane bound transcription factor site 1 0.0357 0.0422 0.0528
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0357 0.0422 1
Loa Loa (eye worm) sirtuin 4 0.0102 0.0106 0.0106
Mycobacterium tuberculosis Probable dehydrogenase 0.0173 0.0193 0.4581
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0009
Echinococcus multilocularis C type lectin domian containing protein 0.0041 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1975 0.2427 0.3969
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0694 0.0839 1
Onchocerca volvulus 0.0018 0.0001 0.0008
Schistosoma mansoni chromatin regulatory protein sir2 0.0694 0.0839 0.0839
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0053 0.0053
Brugia malayi hypothetical protein 0.0149 0.0163 0.0163
Echinococcus granulosus enteropeptidase 0.0024 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Echinococcus granulosus glycoprotein Antigen 5 0.0024 0.0009 0.0009
Echinococcus multilocularis CUB 0.0035 0.0023 0.0028
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0053 0.0045 0.0056
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0107 0.0111 0.1279
Plasmodium falciparum LCCL domain-containing protein 0.0053 0.0045 0.0824
Entamoeba histolytica hypothetical protein 0.0296 0.0346 0.409
Onchocerca volvulus 0.0041 0.0029 0.0452
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Plasmodium falciparum glutathione reductase 0.0026 0.0011 0.0125
Loa Loa (eye worm) transcriptional regulator 0.0102 0.0106 0.0106
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.002 0.0004 0.0004
Brugia malayi p70 ribosomal S6 kinase beta 0.0041 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0041 0.0029 0.0303
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.1975 0.2427 0.2427
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0024 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0001 0.0001
Echinococcus granulosus nervana 2 0.002 0.0004 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0036 0.0036
Schistosoma mansoni integrin beta subunit 0.0387 0.0458 0.0458
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0042 0.003 0.003
Onchocerca volvulus 0.0018 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0088 0.0089 0.0088
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0033 0.002 0.0473
Onchocerca volvulus 0.0018 0.0001 0.0008
Brugia malayi protein kinase C II. 0.0103 0.0106 0.0106
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0019 0.0019
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.002 0.0004 0.0005
Trypanosoma brucei SIR2-like protein 4, putative 0.0102 0.0106 0.114
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0005 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0016 0.0016
Loa Loa (eye worm) acyl carrier protein 0.0025 0.001 0.001
Brugia malayi Zona pellucida-like domain containing protein 0.0023 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0422 0.0686
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0035
Onchocerca volvulus 0.0018 0.0001 0.0008
Loa Loa (eye worm) proprotein convertase 2 0.1975 0.2427 0.2427
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.003 0.0016 0.0016
Trichomonas vaginalis WD repeat domain, putative 0.0275 0.032 0.0519
Loa Loa (eye worm) hypothetical protein 0.0049 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.1618 0.1984 0.1984
Plasmodium falciparum plasmepsin X 0.0036 0.0024 0.0385
Echinococcus multilocularis cubilin 0.0035 0.0023 0.0028
Onchocerca volvulus 0.0018 0.0001 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0023
Onchocerca volvulus 0.0024 0.0009 0.0139
Mycobacterium ulcerans protoporphyrinogen oxidase 0.01 0.0103 0.2438
Echinococcus granulosus GPCR family 2 0.0032 0.0019 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Plasmodium vivax subtilisin-like serine protease, putative 0.0357 0.0422 0.8673
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0015 0.0018
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0035 0.0023 0.0023
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0296 0.0346 0.4038
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis Tolloid protein 1 0.0049 0.0039 0.0049
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0053 0.0045 0.0045
Onchocerca volvulus 0.0041 0.0029 0.0452
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0001 0.0001
Brugia malayi Kringle domain containing protein 0.0035 0.0022 0.0022
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0052 0.0043 0.1013
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0102 0.0106 0.1217
Brugia malayi Sushi domain 0.0041 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Loa Loa (eye worm) endoprotease bli-4 0.8084 1 1
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0001 0.0001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0001 0.0001
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0053 0.0045 0.1067
Trichomonas vaginalis hypothetical protein 0.1618 0.1984 0.3243
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0136 0.0136
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Echinococcus granulosus cubilin 0.0035 0.0023 0.0023
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0016 0.002
Entamoeba histolytica protein kinase, putative 0.0043 0.0032 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0393 0.0466 0.5525
Schistosoma mansoni protein kinase 0.0244 0.0282 0.0282
Echinococcus multilocularis integrin beta 2 0.0489 0.0586 0.0732
Mycobacterium ulcerans thioesterase 0.0045 0.0035 0.0829
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.0003 0.0003
Plasmodium vivax glutathione reductase, putative 0.0076 0.0073 0.1404
Toxoplasma gondii subtilisin SUB8 0.0357 0.0422 0.9568
Loa Loa (eye worm) reprolysin 0.0043 0.0033 0.0032
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0004
Echinococcus multilocularis c src tyrosine kinase 0.0021 0.0005 0.0006
Loa Loa (eye worm) CUTiclin family member 0.0023 0.0008 0.0008
Brugia malayi CUB domain containing protein 0.0039 0.0027 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0042 0.0042
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0005 0.0005
Schistosoma mansoni septate junction protein 0.0063 0.0057 0.0057
Loa Loa (eye worm) AGC/PKN protein kinase 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Schistosoma mansoni adapter molecule crk 0.0021 0.0005 0.0005
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0393 0.0466 0.5492
Toxoplasma gondii subtilisin SUB1 0.0357 0.0422 0.9568
Mycobacterium leprae Polyketide synthase Pks13 0.0078 0.0076 0.1803
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0102 0.0106 0.1204
Brugia malayi von Willebrand factor type A domain containing protein 0.0023 0.0008 0.0008
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.01 0.0103 0.2438
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0027
Toxoplasma gondii subtilisin SUB6 0.0357 0.0422 0.9568
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0244 0.0282 0.0352
Echinococcus multilocularis disintegrin and metalloproteinase 0.0018 0.0001 0.0001
Brugia malayi CUB domain containing protein 0.0035 0.0023 0.0023
Mycobacterium ulcerans polyketide synthase Pks9 0.0033 0.002 0.0473
Onchocerca volvulus 0.0041 0.0029 0.0452
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0018 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0005 0.0006
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0031 0.0017 0.0406
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0694 0.0839 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0016 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0036 0.0045
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0018 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0001 0.0001
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0035 0.0023 0.0023
Toxoplasma gondii bicoid-interacting protein BIN3 0.0107 0.0111 0.2381
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0189 0.0213 0.4331
Echinococcus granulosus collagen alpha 1VII chain 0.0023 0.0008 0.0008
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Echinococcus granulosus chromatin regulatory protein sir2 0.0694 0.0839 0.0839
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Onchocerca volvulus 0.0054 0.0046 0.0711
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Brugia malayi N-terminal motif family protein 0.0186 0.021 0.021
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0142 0.0155 0.0154
Plasmodium falciparum plasmepsin I 0.0036 0.0024 0.0385
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.001
Toxoplasma gondii aspartyl protease ASP5 0.0373 0.0441 1
Schistosoma mansoni hypothetical protein 0.0032 0.0019 0.0019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0042 0.003 0.003
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.0136 0.0136
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.01 0.0103 0.2438
Schistosoma mansoni chromatin regulatory protein sir2 0.0102 0.0106 0.0106
Toxoplasma gondii histone deacetylase SIR2 0.0102 0.0106 0.2259
Entamoeba histolytica protein kinase 2, putative 0.0021 0.0005 0.0015
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0053 0.0066
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.01 0.0103 0.0103
Echinococcus granulosus transmembrane protease serine 3 0.0024 0.0009 0.0009
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0053 0.0044 0.1046
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0023 0.0008 0.001
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Brugia malayi glutathione reductase 0.0076 0.0073 0.0073
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0011 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0008 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0103 0.0106 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0011 0.0072
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0005 0.0006
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0001 0.0001
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Trypanosoma brucei subtilisin peptidase 0.0357 0.0422 0.4962
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0011 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Brugia malayi Eukaryotic aspartyl protease family protein 0.0036 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0023 0.0008 0.0008
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0047 0.0037 0.0876
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0357 0.0422 1
Plasmodium vivax subtilisin-like protease 1 0.0357 0.0422 0.8673
Brugia malayi CUB domain containing protein 0.0035 0.0023 0.0023
Toxoplasma gondii AGC kinase 0.0041 0.0029 0.0497
Mycobacterium tuberculosis Conserved hypothetical protein 0.01 0.0103 0.2438
Onchocerca volvulus 0.002 0.0004 0.0062
Mycobacterium ulcerans NAD-dependent deacetylase 0.0102 0.0106 0.2506
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0024 0.0009 0.0139
Loa Loa (eye worm) hypothetical protein 0.0034 0.002 0.002
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0011 0.0011
Echinococcus granulosus protein arginine N methyltransferase 8 0.0189 0.0213 0.0213
Schistosoma mansoni btb and poz domain-containing protein 0.0053 0.0045 0.0045
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0009
Plasmodium vivax hypothetical protein, conserved 0.01 0.0103 0.203
Brugia malayi endochitinase 0.0075 0.0071 0.0071
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0393 0.0466 0.5525
Brugia malayi Subtilase family protein 0.0357 0.0422 0.0422
Onchocerca volvulus 0.0041 0.0029 0.0452
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0357 0.0422 1
Loa Loa (eye worm) hypothetical protein 0.0492 0.0589 0.0589
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.003 0.0016 0.0225
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0053 0.0044 0.1046
Schistosoma mansoni lamin 0.0027 0.0012 0.0012
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.01 0.0103 0.203
Echinococcus multilocularis chromatin regulatory protein sir2 0.0694 0.0839 0.1049
Schistosoma mansoni chromatin regulatory protein sir2 0.0102 0.0106 0.0106
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0102 0.0106 0.0106
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0192 0.0217 0.5149
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0005 0.0006
Plasmodium falciparum calcium-dependent protein kinase 3 0.003 0.0016 0.0225
Onchocerca volvulus 0.006 0.0053 0.0833
Echinococcus multilocularis adam 0.0067 0.0061 0.0077
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0011 0.008
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0076 0.0073 0.1727
Echinococcus granulosus disintegrin and metalloproteinase 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0024 0.0009 0.0139
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0023
Echinococcus granulosus discoidin domain receptor 0.0053 0.0045 0.0045
Brugia malayi Carm1-pending protein 0.0107 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Loa Loa (eye worm) WD40 repeat protein 0.0275 0.032 0.032
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0057 0.0049 0.0049
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0036 0.0036
Echinococcus granulosus lysine specific histone demethylase 1A 0.01 0.0103 0.0103
Schistosoma mansoni cathepsin D (A01 family) 0.0036 0.0024 0.0024
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0107 0.0111 0.0177
Schistosoma mansoni furin-1 (S08 family) 0.3494 0.4311 0.4311
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.002 0.0004 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0012 0.0012
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0357 0.0422 1
Trypanosoma cruzi Protein kinase B 0.0023 0.0008 0.003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0052 0.0043 0.1013
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0008 0.0008
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0005 0.0006
Loa Loa (eye worm) TAR-binding protein 0.0127 0.0136 0.0136
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.4947 0.6111 0.7644
Schistosoma mansoni memapsin-2 (A01 family) 0.0036 0.0024 0.0024
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0102 0.0106 0.2088
Plasmodium vivax aspartyl proteinase, putative 0.0036 0.0024 0.0385
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Loa Loa (eye worm) glutathione reductase 0.0076 0.0073 0.0073
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0167 0.0185 0.0185
Onchocerca volvulus 0.0023 0.0008 0.0122
Brugia malayi Zona pellucida-like domain containing protein 0.0023 0.0008 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0036 0.0036
Loa Loa (eye worm) microfilarial chitinase 0.0064 0.0058 0.0058
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0064 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0422 0.0686
Trypanosoma cruzi subtilisin peptidase 0.0357 0.0422 0.4998
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0007 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Loa Loa (eye worm) aspartyl protease 6 0.0036 0.0024 0.0024
Plasmodium falciparum subtilisin-like protease 1 0.0357 0.0422 0.8673
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0011 0.0072
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0011
Onchocerca volvulus 0.0024 0.0009 0.0139
Onchocerca volvulus Fatty acid synthase homolog 0.0098 0.01 0.1563
Schistosoma mansoni serine/threonine-protein kinase 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0053
Onchocerca volvulus Putative endochitinase 0.0075 0.0071 0.1113
Schistosoma mansoni growth factor receptor-bound protein 0.0267 0.031 0.031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0009
Mycobacterium tuberculosis Probable reductase 0.0173 0.0193 0.4581
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0422 0.0686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0357 0.0422 0.0686
Onchocerca volvulus 0.0167 0.0185 0.2892
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Echinococcus granulosus cubilin 0.0035 0.0023 0.0023
Onchocerca volvulus 0.0051 0.0042 0.065
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0032 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Loa Loa (eye worm) chitinase I 0.0075 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0045 0.0069
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0053 0.0045 0.0701
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0036 0.0024 0.0024
Echinococcus multilocularis somatostatin receptor 0.0018 0.0001 0.0001
Schistosoma mansoni protein arginine n-methyltransferase 0.0107 0.0111 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0001 0.0001
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0041 0.0029 0.0029
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0102 0.0106 0.114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0036 0.0036
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.002 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0192 0.0217 0.5149
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0107 0.0111 0.0111
Plasmodium vivax SET domain protein, putative 0.006 0.0053 0.1001
Onchocerca volvulus 0.0035 0.0023 0.0353
Giardia lamblia Hypothetical protein 0.0694 0.0839 0.2278
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0214 0.0244 0.0244
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0005 0.0005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0055 0.0047 0.1112
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0422 0.0686
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0021 0.0005 0.0006
Onchocerca volvulus 0.0275 0.032 0.4995
Toxoplasma gondii subtilisin SUB9 0.0357 0.0422 0.9568
Plasmodium vivax hypothetical protein, conserved 0.0102 0.0106 0.2088
Schistosoma mansoni chromatin regulatory protein sir2 0.0694 0.0839 0.0839
Loa Loa (eye worm) CUB domain-containing protein 0.0035 0.0023 0.0023
Echinococcus multilocularis discoidin domain receptor 0.0053 0.0045 0.0056
Schistosoma mansoni SWI/SNF complex-related 0.0042 0.003 0.003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0055 0.0047 0.1112
Brugia malayi endochitinase 0.0075 0.0071 0.0071
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0189 0.0213 0.0213
Echinococcus granulosus serine threonine protein kinase nrc 0.0021 0.0005 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0001 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0106
Echinococcus granulosus tar DNA binding protein 0.0127 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.002 0.0004 0.0004
Plasmodium vivax LCCL domain-containing protein 0.0053 0.0045 0.0824
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0053 0.1039
Toxoplasma gondii aspartyl protease 0.0036 0.0024 0.0369
Entamoeba histolytica SWIRM domain protein 0.0042 0.003 0.0315
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0189 0.0213 0.0213
Entamoeba histolytica SWIRM domain protein 0.0042 0.003 0.0315
Echinococcus multilocularis protoporphyrinogen oxidase 0.01 0.0103 0.0129
Echinococcus granulosus geminin 0.0338 0.0398 0.0398
Trichomonas vaginalis hypothetical protein 0.0053 0.0045 0.0069
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0036 0.0036
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0107 0.0111 0.2381
Trichomonas vaginalis conserved hypothetical protein 0.1618 0.1984 0.3243
Mycobacterium ulcerans monoamine oxidase 0.01 0.0103 0.2438
Mycobacterium leprae Possible secreted protease 0.0357 0.0422 1
Loa Loa (eye worm) subtilase 0.0357 0.0422 0.0422
Brugia malayi Disintegrin family protein 0.0018 0.0001 0.0001
Plasmodium vivax aspartyl protease, putative 0.0036 0.0024 0.0385
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0005 0.0005
Mycobacterium ulcerans thioesterase TesA 0.0045 0.0035 0.0829
Onchocerca volvulus Putative endochitinase 0.0075 0.0071 0.1113
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0004 0.0004
Toxoplasma gondii subtilisin SUB7 0.0357 0.0422 0.9568
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0035 0.0022 0.0353
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0357 0.0422 1
Echinococcus multilocularis neuroendocrine convertase 2 0.5112 0.6316 0.79
Brugia malayi NAD-dependent deacetylase SIRT1 0.0102 0.0106 0.0106
Brugia malayi Sex muscle abnormal protein 5 0.0267 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.0103
Echinococcus multilocularis discoidin domain containing receptor 2 0.0053 0.0045 0.0056
Brugia malayi Calcium binding EGF domain containing protein 0.0045 0.0035 0.0035
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.002 0.0004 0.0005
Brugia malayi transcriptional regulator, Sir2 family protein 0.0102 0.0106 0.0106
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0357 0.0422 0.0422
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.002 0.0004 0.0005
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.003 0.0016 0.0058
Onchocerca volvulus 0.01 0.0103 0.1601
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0055 0.0047 0.1112
Entamoeba histolytica protein kinase, putative 0.0031 0.0018 0.0164
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0102 0.0106 0.0132
Plasmodium vivax aspartyl protease, putative 0.0036 0.0024 0.0385
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0043 0.0033 0.0032
Echinococcus multilocularis serine:threonine protein kinase 38 0.002 0.0004 0.0005
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0052 0.0043 0.1013
Leishmania major UDP-galactopyranose mutase 0.01 0.0103 0.1105
Loa Loa (eye worm) hypothetical protein 0.0034 0.002 0.002
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0004
Trichomonas vaginalis set domain proteins, putative 0.0478 0.0571 0.093
Schistosoma mansoni cathepsin D (A01 family) 0.0036 0.0024 0.0024
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0036 0.0024 0.0024
Loa Loa (eye worm) AGC/NDR protein kinase 0.002 0.0004 0.0004
Onchocerca volvulus 0.0024 0.0009 0.0139
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0008 0.0053
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0023 0.0008 0.0053
Toxoplasma gondii F5/8 type C domain-containing protein 0.0053 0.0045 0.0856
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0001 0.0001
Brugia malayi Muscle positioning protein 4 0.003 0.0017 0.0016
Onchocerca volvulus Putative endochitinase 0.0075 0.0071 0.1113
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0189 0.0213 0.0345
Onchocerca volvulus 0.0041 0.0029 0.0452
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Onchocerca volvulus 0.0357 0.0422 0.6583
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Leishmania major sir2-family protein-like protein 0.0102 0.0106 0.114
Schistosoma mansoni tyrosine kinase 0.0021 0.0005 0.0005
Plasmodium vivax plasmepsin V, putative 0.0409 0.0486 1
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0043 0.0033 0.0032
Brugia malayi Lectin C-type domain containing protein 0.0035 0.0023 0.0023
Onchocerca volvulus 0.0041 0.0029 0.0452
Echinococcus multilocularis serotonin receptor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0024
Loa Loa (eye worm) CUB domain-containing protein 0.0035 0.0023 0.0023
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0189 0.0213 0.0345
Mycobacterium leprae Probable polyketide synthase Pks1 0.0055 0.0047 0.1112
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0005 0.0005
Echinococcus multilocularis geminin 0.0338 0.0398 0.0497
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0023 0.0008 0.0008
Toxoplasma gondii type I fatty acid synthase, putative 0.0039 0.0027 0.0435
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0024
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0009
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0001 0.0001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0102 0.0106 0.0168
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Toxoplasma gondii SWIRM domain-containing protein 0.0042 0.003 0.0521
Mycobacterium ulcerans dehydrogenase 0.01 0.0103 0.2438
Schistosoma mansoni hypothetical protein 0.0338 0.0398 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0014 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0019 0.0019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0053 0.0067
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Loa Loa (eye worm) AGC/AKT protein kinase 0.0043 0.0032 0.0032
Plasmodium vivax protoporphyrinogen oxidase, putative 0.01 0.0103 0.203
Brugia malayi RNA binding protein 0.0127 0.0136 0.0136
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0053 0.1254
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0107 0.0111 0.1267
Echinococcus multilocularis nervana 2 0.002 0.0004 0.0005
Brugia malayi TAR-binding protein 0.0127 0.0136 0.0136
Trypanosoma cruzi UDP-galactopyranose mutase 0.01 0.0103 0.117
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0008
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0192 0.0217 0.5149
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0001 0.0001
Echinococcus granulosus c src tyrosine kinase 0.0021 0.0005 0.0005
Plasmodium falciparum glutathione reductase 0.0076 0.0073 0.1404
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0034 0.002 0.002
Schistosoma mansoni dock 0.0053 0.0045 0.0045
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.8084 1 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.4947 0.6111 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0052 0.0043 0.1013
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.003 0.0045
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0107 0.0111 0.0139
Schistosoma mansoni vav2 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0039 0.0027 0.0645
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0005 0.0005
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Toxoplasma gondii type I fatty acid synthase, putative 0.0055 0.0047 0.0901
Plasmodium falciparum plasmepsin VIII, putative 0.0036 0.0024 0.0385
Brugia malayi Cam kinase protein 1 0.003 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0027 0.0013 0.0114
Schistosoma mansoni amine oxidase 0.01 0.0103 0.0103
Onchocerca volvulus 0.0027 0.0012 0.0182

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 100 uM Cytotoxicity against uninfected human foreskin fibroblast(HFF cells) ChEMBL. 2846837

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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