Detailed information for compound 1185675

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 756.788 | Formula: C35H36N10O8S
  • H donors: 7 H acceptors: 10 LogP: 1.7 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2Nc1ccc(cc1)CC(=O)Nc1ccc(cc1)CC(=O)NCC/N=C(/Nc1ccc(cc1)[N+](=O)[O-])\S
  • InChi: 1S/C35H36N10O8S/c46-17-26-30(49)31(50)34(53-26)44-19-40-29-32(38-18-39-33(29)44)42-23-7-3-21(4-8-23)16-28(48)41-22-5-1-20(2-6-22)15-27(47)36-13-14-37-35(54)43-24-9-11-25(12-10-24)45(51)52/h1-12,18-19,26,30-31,34,46,49-50H,13-17H2,(H,36,47)(H,41,48)(H2,37,43,54)(H,38,39,42)/t26-,30-,31-,34?/m1/s1
  • InChiKey: QEDXFGSZFSLPSU-TWADQQKPSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Adenosine A1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis neuropeptide receptor Adenosine A1 receptor   326 aa 299 aa 22.4 %
Onchocerca volvulus Ubiquinol-cytochrome-c reductase complex assembly factor 1 homolog Adenosine A1 receptor   326 aa 286 aa 22.7 %
Schistosoma japonicum Alpha-1A adrenergic receptor, putative Adenosine A1 receptor   326 aa 295 aa 28.1 %
Loa Loa (eye worm) neuropeptide F receptor Adenosine A1 receptor   326 aa 316 aa 19.9 %
Onchocerca volvulus Adenosine A1 receptor   326 aa 304 aa 21.1 %
Echinococcus granulosus neuropeptide receptor Adenosine A1 receptor   326 aa 299 aa 22.4 %
Echinococcus granulosus thyrotropin releasing hormone receptor Adenosine A1 receptor   326 aa 321 aa 23.1 %
Onchocerca volvulus Adenosine A1 receptor   326 aa 306 aa 21.2 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Adenosine A1 receptor   326 aa 317 aa 24.6 %
Schistosoma mansoni peptide (allatostatin)-like receptor Adenosine A1 receptor   326 aa 327 aa 24.8 %
Echinococcus granulosus allatostatin A receptor Adenosine A1 receptor   326 aa 303 aa 24.1 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Adenosine A1 receptor   326 aa 321 aa 22.7 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Adenosine A1 receptor   326 aa 315 aa 21.6 %
Schistosoma mansoni dro/myosuppressin receptor Adenosine A1 receptor   326 aa 326 aa 22.1 %
Loa Loa (eye worm) hypothetical protein Adenosine A1 receptor   326 aa 300 aa 24.3 %
Echinococcus multilocularis allatostatin A receptor Adenosine A1 receptor   326 aa 303 aa 24.1 %
Schistosoma japonicum 5-hydroxytryptamine receptor 4, putative Adenosine A1 receptor   326 aa 286 aa 26.9 %
Schistosoma mansoni neuropeptide receptor Adenosine A1 receptor   326 aa 311 aa 21.2 %
Brugia malayi hypothetical protein Adenosine A1 receptor   326 aa 305 aa 21.0 %
Schistosoma mansoni neuropeptide receptor Adenosine A1 receptor   326 aa 274 aa 22.6 %
Onchocerca volvulus Adenosine A1 receptor   326 aa 323 aa 20.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0059 0.0053
Plasmodium falciparum transporter, putative 0.0361 0.1651 1
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0194 0.0194
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Plasmodium vivax amine transporter, putative 0.0361 0.1651 1
Brugia malayi Uncoordinated protein 44 0.0015 0.0015 0.0004
Onchocerca volvulus 0.0063 0.0242 0.0234
Schistosoma mansoni adenoreceptor 0.0063 0.0242 0.0242
Echinococcus granulosus serotonin receptor 0.0063 0.0242 0.0242
Leishmania major cytochrome p450-like protein 0.0022 0.0049 0.0119
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Entamoeba histolytica hypothetical protein 0.0028 0.0079 0.129
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0053 0.0194 0.0188
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0165 0.0165
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0063 0.0242 0.0242
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0049 0.0279
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0059 0.0059
Schistosoma mansoni alpha-1 adrenergic receptor 0.0063 0.0242 0.0242
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0361 0.1651 0.1651
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0016 0.0019 0.0013
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0016 0.0019 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0139 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0165 0.0159
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0175 0.0164
Brugia malayi mbt repeat family protein 0.0047 0.0165 0.0154
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0063 0.0242 0.0231
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0113 0.0113
Leishmania major sterol C-24 reductase, putative 0.0048 0.0171 0.0471
Mycobacterium ulcerans lipase LipD 0.0036 0.0113 0.1483
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0089 0.1724
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0176 0.0176
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0307 0.0307
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Giardia lamblia PHD finger protein 15 0.0044 0.0151 0.6512
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Brugia malayi Abnormal catecholamine distribution protein 1 0.02 0.0888 0.0878
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0463 0.1306
Loa Loa (eye worm) MBCTL1 0.0053 0.0195 0.0189
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Schistosoma mansoni polycystin 1-related 0.004 0.0135 0.0135
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0175 0.0164
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0077 0.0071
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0028 0.0059
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0668 0.0668
Echinococcus granulosus neuropeptide receptor 0.0063 0.0242 0.0242
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0068 0.035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0092 0.1002
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0059 0.0048
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0016 0.0016
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0269 0.0745
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.0242 0.0242
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0194 0.0183
Echinococcus multilocularis GPCR, family 2 0.0049 0.0175 0.0175
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0194 0.0194
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0256 0.0256
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0089 0.1724
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0019 0.0013
Echinococcus multilocularis nAChR subunit 0.0028 0.0079 0.0079
Schistosoma mansoni ATP-binding cassette transporter 0.0153 0.0669 0.0669
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.0673 0.0663
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0463 0.1314
Brugia malayi mbt repeat family protein 0.0047 0.0165 0.0154
Onchocerca volvulus 0.0063 0.0242 0.0234
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0113 0.0918
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.0242 0.0236
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0049 0.0279
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0049 0.0279
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0009
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0216 0.4426
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0059 0.0059
Onchocerca volvulus 0.0024 0.0059 0.0052
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0063 0.0242 0.0231
Onchocerca volvulus 0.0361 0.1651 0.1645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0063 0.0242 0.0234
Schistosoma mansoni hypothetical protein 0.0047 0.0165 0.0165
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Mycobacterium tuberculosis Conserved protein 0.0036 0.0113 0.0918
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0028 0.0187
Schistosoma mansoni lamin 0.0028 0.0077 0.0077
Echinococcus granulosus JmjC domain containing protein 4 0.0014 0.0011 0.0011
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0019 0.0013
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.0194 0.0194
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0113 0.0293
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0079 0.0073
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0059 0.0059
Toxoplasma gondii PHD-finger domain-containing protein 0.0044 0.0151 0.0851
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0113 0.2227
Brugia malayi phosphofructokinase 0.0113 0.0479 0.0469
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Schistosoma mansoni histamine h1 receptor 0.0063 0.0242 0.0242
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0098 0.0409 0.3888
Brugia malayi intermediate filament protein 0.0028 0.0077 0.0066
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0124 0.1755
Schistosoma mansoni hypothetical protein 0.0695 0.3231 0.3231
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0216 0.0602
Loa Loa (eye worm) inositol-1 0.011 0.0463 0.0458
Echinococcus granulosus lamin 0.0028 0.0077 0.0077
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0479 0.1351
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0053 0.0194 0.0194
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0021 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0063 0.0242 0.0242
Onchocerca volvulus 0.0063 0.0242 0.0234
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0019 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0089 0.1724
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0015 0.0015
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0028 0.0059
Brugia malayi Cation transporter family protein 0.0053 0.0194 0.0183
Echinococcus granulosus glutamate receptor 2 0.0169 0.0743 0.0743
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.0242 0.0242
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0176 0.0176
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0256 0.025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0169
Echinococcus multilocularis NMDA receptor 0.0057 0.0212 0.0212
Schistosoma mansoni sodium-dependent amino acid transporter 0.0361 0.1651 0.1651
Echinococcus multilocularis serotonin receptor 0.0063 0.0242 0.0242
Schistosoma mansoni rab6-interacting 0.004 0.0135 0.0135
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0195 0.0195
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0132 0.0132
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0194 0.0183
Echinococcus multilocularis glutamate receptor 2 0.0153 0.0668 0.0668
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0269 0.0269
Echinococcus granulosus microtubule associated protein 2 0.2075 0.9753 0.9753
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Brugia malayi Inositol-1 0.011 0.0463 0.0453
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0049 0.0043
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.0063 0.0242 0.0242
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0059 0.0149
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0038 0.0124 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0361 0.1651 0.1651
Brugia malayi jmjC domain containing protein 0.0053 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0016 0.0019 0.0019
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0049 0.0119
Echinococcus multilocularis lamin b receptor 0.0092 0.0381 0.0381
Brugia malayi Muscleblind-like protein 0.0146 0.0634 0.0624
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0063 0.0242 0.0236
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0143 0.062 0.062
Onchocerca volvulus 0.0063 0.0242 0.0234
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0014 0.0012 0.0002
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0113 0.1483
Loa Loa (eye worm) hypothetical protein 0.0103 0.0432 0.0426
Echinococcus granulosus neuropeptide receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0242 0.0242
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0063 0.0242 0.0242
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0028 0.0028
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Echinococcus granulosus neuropeptide s receptor 0.0063 0.0242 0.0242
Onchocerca volvulus 0.0063 0.0242 0.0234
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.0242 0.0242
Brugia malayi PHD-finger family protein 0.0044 0.0151 0.014
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.02 0.0888 0.0883
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0123 0.0123
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0171 0.0471
Leishmania major protein kinase, putative 0.0018 0.0031 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Plasmodium vivax hypothetical protein, conserved 0.0361 0.1651 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0216 0.0602
Brugia malayi Glutamate receptor 2 precursor 0.0153 0.0668 0.0658
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0479 1
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0242 0.0242
Echinococcus multilocularis tyrosine kinase 0.0016 0.0019 0.0019
Echinococcus granulosus neuropeptide receptor A26 0.0063 0.0242 0.0242
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0015 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0063 0.0242 0.0242
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0216 0.1252
Trypanosoma cruzi C-14 sterol reductase, putative 0.0092 0.0381 0.1076
Loa Loa (eye worm) hypothetical protein 0.0382 0.1749 0.1744
Echinococcus granulosus geminin 0.0695 0.3231 0.3231
Echinococcus multilocularis glutamate receptor NMDA 0.0082 0.0332 0.0332
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.011 0.0463 0.9635
Onchocerca volvulus 0.0047 0.0165 0.0157
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0089 0.1724
Leishmania major extracellular receptor, putative 0.0016 0.0019 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0176 0.0176
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0059 0.0053
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.0194 0.0188
Loa Loa (eye worm) RecQ helicase 0.0022 0.0048 0.0042
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.0194 0.0183
Schistosoma mansoni nAChR subunit 0.0024 0.0059 0.0059
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0059 0.0139
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.001
Brugia malayi beta-lactamase family protein 0.0036 0.0113 0.0102
Schistosoma mansoni phd/f-box containing protein 0.0014 0.0011 0.0011
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0089 0.1512
Schistosoma mansoni vesicular acetylcholine transporter 0.0656 0.3047 0.3047
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0028 0.0049
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0068 0.035
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Schistosoma mansoni opsin-like receptor 0.0063 0.0242 0.0242
Schistosoma mansoni protein kinase 0.0016 0.0019 0.0019
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0016 0.0019 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0479 1
Echinococcus granulosus jumonji domain containing protein 0.0061 0.0231 0.0231
Brugia malayi hypothetical protein 0.0017 0.0024 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0511 0.0505
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0079 0.0068
Brugia malayi Metabotropic glutamate receptor precursor. 0.0016 0.0019 0.0008
Brugia malayi Cytochrome P450 family protein 0.0031 0.0092 0.0081
Schistosoma mansoni lamin 0.0028 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Echinococcus multilocularis receptor type guanylyl cyclase 0.0016 0.0019 0.0019
Schistosoma mansoni amine GPCR 0.0063 0.0242 0.0242
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0063 0.0242 0.0242
Brugia malayi G-protein coupled receptor 0.0063 0.0242 0.0231
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0006
Onchocerca volvulus 0.0063 0.0242 0.0234
Brugia malayi ORL1-like opioid receptor 0.0063 0.0242 0.0231
Echinococcus granulosus sex peptide receptor 0.0063 0.0242 0.0242
Brugia malayi hypothetical protein 0.0228 0.1024 0.1015
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0165 0.0165
Brugia malayi 6-phosphofructokinase 0.0113 0.0479 0.0469
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Schistosoma mansoni biogenic amine receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0015 0.0009
Echinococcus granulosus inositol monophosphatase 1 0.011 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Schistosoma mansoni hypothetical protein 0.0049 0.0175 0.0175
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0048 0.0048
Schistosoma mansoni sodium/chloride dependent transporter 0.0361 0.1651 0.1651
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0656 0.3047 0.3041
Echinococcus granulosus tachykinin peptides receptor 99D 0.0063 0.0242 0.0242
Leishmania major cytochrome p450-like protein 0.0031 0.0092 0.0243
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0059 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Loa Loa (eye worm) hypothetical protein 0.0047 0.0165 0.0159
Brugia malayi Serotonin receptor 0.0063 0.0242 0.0231
Echinococcus granulosus RUN 0.004 0.0135 0.0135
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0014 0.0011 0.001
Leishmania major cytochrome p450-like protein 0.0022 0.0049 0.0119
Brugia malayi Death domain containing protein 0.0015 0.0015 0.0004
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0063 0.0242 0.0242
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0656 0.3047 0.3042
Brugia malayi PAS domain containing protein 0.0051 0.0187 0.0177
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0063 0.0242 0.0231
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0012 0.0005
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0743 0.0743
Schistosoma mansoni rab6-interacting 0.004 0.0135 0.0135
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0194 0.0194
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.0242 0.0236
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus granulosus glutamate receptor subunit protein glur 0.0057 0.0212 0.0212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Echinococcus granulosus lamin b receptor 0.0092 0.0381 0.0381
Brugia malayi Tachykinin-like peptides receptor 99D 0.0063 0.0242 0.0231
Echinococcus granulosus somatostatin receptor 0.0063 0.0242 0.0242
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0063 0.0242 0.0242
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0049 0.0279
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0015 0.0015
Schistosoma mansoni amine GPCR 0.0063 0.0242 0.0242
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0057 0.0212 0.0212
Echinococcus granulosus tm gpcr rhodopsin 0.1103 0.5161 0.5161
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0059 0.0294
Echinococcus granulosus metabotropic glutamate receptor 2 0.0016 0.0019 0.0019
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0269 0.0754
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0021 0.001
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0028 0.0049
Loa Loa (eye worm) beta-lactamase 0.0036 0.0113 0.0107
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0053 0.0194 0.0183
Schistosoma mansoni opsin-like receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi G protein-coupled receptor 0.0063 0.0242 0.0231
Schistosoma mansoni microtubule-associated protein tau 0.2075 0.9753 0.9753
Brugia malayi follicle stimulating hormone receptor 0.0302 0.1373 0.1364
Mycobacterium leprae Probable lipase LipE 0.0036 0.0113 0.2227
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0194 0.0183
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0021 0.0021
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0256 0.0256
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0059 0.0059
Brugia malayi Dopamine receptor protein 1 0.0063 0.0242 0.0231
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.0242 0.0242
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0139 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Trypanosoma cruzi extracellular receptor, putative 0.0016 0.0019 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0194 0.0194
Schistosoma mansoni glutamate receptor NMDA 0.0325 0.1483 0.1483
Schistosoma mansoni jumonji/arid domain-containing protein 0.0053 0.0194 0.0194
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0079 0.0068
Brugia malayi PHD-finger family protein 0.0014 0.0012 0.0001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Echinococcus granulosus peregrin 0.0044 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0127 0.0547 0.0541
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.011 0.0463 1
Echinococcus multilocularis somatostatin receptor 0.0063 0.0242 0.0242
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0111 0.2201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.0242 0.0242
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0172 0.076 0.0754
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0028 0.0059
Loa Loa (eye worm) melatonin receptor type 1A 0.0063 0.0242 0.0236
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Entamoeba histolytica hypothetical protein 0.0024 0.0059 0.0866
Schistosoma mansoni cytochrome P450 0.0022 0.0049 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.1093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis fmrfamide receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0146 0.0634 0.0629
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0113 0.2227
Brugia malayi putative neuropeptide receptor NPR1 0.0063 0.0242 0.0231
Echinococcus multilocularis peregrin 0.0044 0.0151 0.0151
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni phosphatidylserine receptor 0.0014 0.0011 0.0011
Onchocerca volvulus 0.004 0.0135 0.0127
Brugia malayi hypoxia-induced factor 1 0.0159 0.0697 0.0686
Schistosoma mansoni neuropeptide receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis lamin 0.0028 0.0077 0.0077
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0089 0.0475
Echinococcus granulosus metabotropic glutamate receptor 5 0.0016 0.0019 0.0019
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0063 0.0242 0.0242
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0113 0.0113
Onchocerca volvulus Neuropeptide F receptor homolog 0.0063 0.0242 0.0234
Loa Loa (eye worm) cytochrome P450 0.0022 0.0049 0.0043
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0194 0.0194
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0063 0.0242 0.0236
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0269 0.0754
Echinococcus multilocularis neuropeptide receptor 0.0063 0.0242 0.0242
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0216 0.4284
Loa Loa (eye worm) LGC-31 protein 0.0053 0.0194 0.0188
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0008 0.0008
Brugia malayi hypothetical protein 0.004 0.0135 0.0124
Schistosoma mansoni intermediate filament proteins 0.0028 0.0077 0.0077
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0792 0.3689 0.3689
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0014 0.0012 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0098 0.0409 0.8514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus multilocularis phd:f box containing protein 0.0014 0.0011 0.0011
Brugia malayi TAR-binding protein 0.0066 0.0256 0.0245
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Onchocerca volvulus 0.0361 0.1651 0.1645
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0049 0.0279
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0216 0.3893
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Toxoplasma gondii hypothetical protein 0.0361 0.1651 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0014 0.0012 0.0005
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0256 0.0245
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0175 0.0169
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0028 0.0028
Brugia malayi putative neuropeptide receptor 0.0063 0.0242 0.0231
Brugia malayi larval opioid receptor 0.0063 0.0242 0.0231
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Loa Loa (eye worm) TYRA-2 protein 0.0063 0.0242 0.0236
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0028 0.0059
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0021 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0479 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus granulosus receptor type guanylyl cyclase 0.0016 0.0019 0.0019
Echinococcus granulosus bloom syndrome protein 0.0022 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0049 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0048 0.0171 0.0165
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0049 0.0119
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0068 0.0175
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0063 0.0242 0.0242
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0028 0.0075 0.0069
Brugia malayi vesicular acetylcholine transporter unc-17 0.0656 0.3047 0.3039
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0063 0.0242 0.0234
Echinococcus granulosus G protein coupled receptor 139 0.0063 0.0242 0.0242
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0015 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0014 0.0011 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0068 0.035
Echinococcus granulosus dro:myosuppressin receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0511 0.0505
Brugia malayi sulfakinin receptor protein 0.0063 0.0242 0.0231
Onchocerca volvulus 0.0063 0.0242 0.0234
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.1019 1
Brugia malayi hypothetical protein 0.0024 0.0059 0.0048
Loa Loa (eye worm) hypothetical protein 0.0044 0.0151 0.0145
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Schistosoma mansoni hypothetical protein 0.0063 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0049 0.0109
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0743 0.0743
Brugia malayi AKH receptor 0.0063 0.0242 0.0231
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0113 0.2227
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0361 0.1651 0.1642
Schistosoma mansoni metabotropic glutamate receptor 0.0016 0.0019 0.0019
Echinococcus granulosus Ankyrin 0.0015 0.0016 0.0016
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0634 0.0634
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0021
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0479 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0063 0.0242 0.0242
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0012
Schistosoma mansoni ap endonuclease 0.0058 0.0216 0.0216
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0113 0.0113
Brugia malayi G protein-coupled receptor F59B2.13 0.0063 0.0242 0.0231
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0165 0.0165
Echinococcus multilocularis RUN 0.004 0.0135 0.0135
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0361 0.1651 0.1642
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.004 0.0135 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0016 0.0019 0.0012
Onchocerca volvulus 0.0063 0.0242 0.0234
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0747 0.3476 0.3472
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0216 0.1252
Echinococcus granulosus lysine specific demethylase 6a 0.0014 0.0011 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Trypanosoma cruzi C-14 sterol reductase, putative 0.0092 0.0381 0.1076
Onchocerca volvulus 0.0063 0.0242 0.0234
Echinococcus granulosus glutamate NMDA receptor subunit 0.0325 0.1483 0.1483
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0016 0.0019 0.0013
Echinococcus multilocularis nmda type glutamate receptor 0.0098 0.0407 0.0407
Trichomonas vaginalis esterase, putative 0.0036 0.0113 0.2227
Brugia malayi hypothetical protein 0.0016 0.0019 0.0008
Echinococcus granulosus single minded 2 0.0042 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Echinococcus granulosus g protein coupled receptor 0.0063 0.0242 0.0242
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0063 0.0242 0.0231
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0028 0.0103
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0028 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0015 0.0015
Brugia malayi neuropeptide F receptor 0.0063 0.0242 0.0231
Loa Loa (eye worm) hypothetical protein 0.0154 0.0673 0.0668
Onchocerca volvulus 0.0053 0.0194 0.0186
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0668 0.0668
Entamoeba histolytica myo-inositol monophosphatase, putative 0.011 0.0463 0.9658
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Echinococcus multilocularis sodium and chloride dependent glycine 0.0361 0.1651 0.1651
Mycobacterium leprae putative cytochrome p450 0.0022 0.0049 0.0874
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.0673 0.0668
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0242 0.0242
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0269 0.0754
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0194 0.0194
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0049 0.0279
Leishmania major hypothetical protein, conserved 0.0036 0.0113 0.0303
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0113 0.0918
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0165 0.0154
Echinococcus multilocularis musashi 0.0028 0.0077 0.0077
Brugia malayi Glutamate receptor 1 precursor 0.0153 0.0668 0.0658
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.0194 0.0188
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0079 0.0068
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0089 0.0475
Echinococcus multilocularis glutamate receptor 2 0.0169 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.0063 0.0242 0.0242
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Brugia malayi 6-phosphofructokinase 0.0113 0.048 0.0469
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0016 0.0019 0.0008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0089 0.0475
Schistosoma mansoni amine GPCR 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.0697 0.0691
Echinococcus granulosus g protein coupled receptor 0.0063 0.0242 0.0242
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0028 0.0187
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0269 0.0263
Brugia malayi beta-lactamase 0.0036 0.0113 0.0102
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0063 0.0242 0.0234
Echinococcus multilocularis neuropeptide receptor A26 0.0063 0.0242 0.0242
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Onchocerca volvulus 0.0036 0.0113 0.0105
Brugia malayi G-protein coupled receptor 0.0063 0.0242 0.0231
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0028 0.0059
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0028 0.0022
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0216 0.021
Echinococcus multilocularis lysine specific demethylase 6a 0.0014 0.0011 0.0011
Onchocerca volvulus 0.0361 0.1651 0.1645
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.0242 0.0242
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.0194 0.0194
Schistosoma mansoni lipoxygenase 0.0178 0.0786 0.0786
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0743 0.0743
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0089 0.0494
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0063 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Echinococcus granulosus phd:f box containing protein 0.0014 0.0011 0.0011
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0479 0.0473
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0195 0.0195
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0059 0.0059
Onchocerca volvulus 0.0063 0.0242 0.0234
Schistosoma mansoni single-minded 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0127 0.0547 0.054
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0107
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0059 0.0053
Echinococcus granulosus death domain containing protein 0.0015 0.0015 0.0015
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0216 0.0216
Loa Loa (eye worm) RNA binding protein 0.0066 0.0256 0.025
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0021 0.0061
Echinococcus multilocularis vesicular acetylcholine transporter 0.0656 0.3047 0.3047
Schistosoma mansoni neuropeptide receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0194 0.0194
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0068 0.0175
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni biogenic amine receptor 0.0063 0.0242 0.0242
Onchocerca volvulus 0.0063 0.0242 0.0234
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0063 0.0242 0.0236
Brugia malayi hypothetical protein 0.0172 0.076 0.075
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0092 0.0086
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0743 0.0743
Echinococcus granulosus tyrosine kinase 0.0016 0.0019 0.0019
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0135 0.0135
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1103 0.5161 0.5161
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0021
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0361 0.1651 0.1651
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0216 0.0602
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0079 0.0068
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0092 0.0243
Leishmania major hypothetical protein, conserved 0.0014 0.0011 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0176 0.017
Schistosoma mansoni neuropeptide f receptor 76f 0.0063 0.0242 0.0242
Schistosoma mansoni biogenic amine receptor 0.0063 0.0242 0.0242
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.0194 0.0194
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0049 0.0279
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Brugia malayi Dopamine receptor protein 2 0.0063 0.0242 0.0231
Mycobacterium tuberculosis Conserved protein 0.0036 0.0113 0.0918
Echinococcus granulosus lysine specific demethylase 5A 0.0053 0.0194 0.0194
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0049 0.0175 0.0175
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0089 0.0475
Onchocerca volvulus 0.0028 0.0077 0.007
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.011 0.0463 0.2758
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni netrin receptor unc5 0.0015 0.0015 0.0015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis sex peptide receptor 0.0063 0.0242 0.0242
Onchocerca volvulus 0.0028 0.0079 0.0071
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0021 0.0061
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0668 0.0668
Brugia malayi Dopamine receptor 0.0063 0.0242 0.0231
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0028 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0107
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.0242 0.0242
Onchocerca volvulus 0.004 0.0135 0.0127
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0113 0.0918
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0049 0.0279
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Schistosoma mansoni hypothetical protein 0.0295 0.1338 0.1338
Echinococcus granulosus g-protein coupled receptor 0.0063 0.0242 0.0242
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0028 0.0059
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0151 0.0851
Schistosoma mansoni hypothetical protein 0.0695 0.3231 0.3231
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0242 0.0242
Brugia malayi Cation transporter family protein 0.0053 0.0194 0.0183
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0021 0.0015
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0479 0.4591
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0194 0.0183
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0269 0.0258
Brugia malayi metabotropic glutamate receptor type 2 0.0016 0.0019 0.0008
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0028 0.0022
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0361 0.1651 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Brugia malayi isocitrate dehydrogenase 0.0016 0.0021 0.001
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0194 0.0194
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0028 0.0049
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0113 0.2227
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.004 0.0135 0.0129
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) glutamate receptor 0.0016 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Mycobacterium ulcerans hypothetical protein 0.0036 0.0113 0.1483
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0256 0.0256
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0049 0.0279
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0194 0.0183
Onchocerca volvulus 0.0063 0.0242 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.0194 0.0183
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0063 0.0242 0.0242
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0668 0.0668
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0026 0.0068 0.0062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0195 0.0189
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0479 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0089 0.1724
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0127 0.0547 0.0547
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.0194 0.0183
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.0242 0.0236
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0463 0.1314
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0014 0.0012 0.0005
Brugia malayi neuropeptide F receptor 0.0063 0.0242 0.0231
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni amine GPCR 0.0063 0.0242 0.0242
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0479 0.136
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0059 0.0059
Schistosoma mansoni metabotropic glutamate receptor 0.0016 0.0019 0.0019
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0028 0.0059
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0135 0.0135
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0059 0.0059
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0063 0.0242 0.0242
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0165 0.0165
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0019 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus granulosus glutamate receptor NMDA 0.0082 0.0332 0.0332
Echinococcus granulosus GPCR family 2 0.0049 0.0175 0.0175
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0049 0.0231
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0169 0.0743 0.0743
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0479 0.136
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0194 0.0194
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0135 0.0135
Brugia malayi AF-10 protein 0.0014 0.0012 0.0001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0113 0.0107
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0479 0.0394
Echinococcus granulosus vesicular acetylcholine transporter 0.0656 0.3047 0.3047
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0107
Schistosoma mansoni glutamate receptor NMDA 0.0251 0.1131 0.1131
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0008 0.0008
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0743 0.0743
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0668 0.0668
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0113 0.0303
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0049 0.0279
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0194 0.0194
Echinococcus granulosus alpha 1A adrenergic receptor 0.0063 0.0242 0.0242
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0216 0.0216
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0135 0.0756
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Brugia malayi Doublecortin family protein 0.004 0.0135 0.0124
Brugia malayi hypothetical protein 0.0024 0.0059 0.0048
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0089 0.0475
Brugia malayi Melatonin receptor type 1A 0.0063 0.0242 0.0231
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0194 0.0194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0195 0.0195
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0092 0.0086
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0113 0.1483
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.0242 0.0242
Schistosoma mansoni vesicular amine transporter 0.02 0.0888 0.0888
Echinococcus granulosus PHD finger protein rhinoceros 0.0044 0.0151 0.0151
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0008 0.0008
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0049 0.0874
Schistosoma mansoni protein phosphatase 2C 0.0014 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0127 0.0547 0.054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0077 0.0071
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0021 0.0061
Echinococcus multilocularis dro:myosuppressin receptor 0.0063 0.0242 0.0242
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0028 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0053 0.0194 0.0194
Echinococcus granulosus sodium and chloride dependent glycine 0.0361 0.1651 0.1651
Brugia malayi hypothetical protein 0.0024 0.0059 0.0048
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0021 0.0039
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0479 0.0479
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0059 0.0048
Echinococcus multilocularis muscleblind protein 0.0146 0.0634 0.0634
Echinococcus granulosus nAChR subunit 0.0053 0.0194 0.0194
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0016 0.0019 0.0019
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0479 0.0479
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0048 0.0037
Schistosoma mansoni opsin-like receptor 0.0063 0.0242 0.0242
Mycobacterium tuberculosis Conserved protein 0.0036 0.0113 0.0918
Schistosoma mansoni jumonji domain containing protein 0.0113 0.0481 0.0481
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0194 0.0194
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0302 0.1373 0.1368
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0124 0.0124
Toxoplasma gondii ABC1 family protein 0.0036 0.0113 0.062
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0049 0.0279
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0048 0.0853
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0216 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0028 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0256 0.0256
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.0242 0.0242
Echinococcus granulosus 7TM GPCR rhodopsin 0.0063 0.0242 0.0242
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0021 0.0061
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0024 0.0059 0.0052
Onchocerca volvulus 0.0053 0.0194 0.0186
Loa Loa (eye worm) hypothetical protein 0.1332 0.6242 0.6239
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis Ankyrin 0.0015 0.0016 0.0016
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0026 0.0026
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0443 0.0432
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0089 0.0494
Leishmania major hypothetical protein, conserved 0.0026 0.0068 0.0175
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0012 0.0012
Onchocerca volvulus 0.0053 0.0194 0.0186
Leishmania major C-14 sterol reductase, putative 0.0092 0.0381 0.1076
Toxoplasma gondii PHD-finger domain-containing protein 0.0044 0.0151 0.0851
Onchocerca volvulus 0.0028 0.0077 0.007
Onchocerca volvulus Alhambra homolog 0.0044 0.0151 0.0143
Echinococcus multilocularis jumonji domain containing 1A 0.0014 0.0011 0.0011
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0361 0.1651 0.1646
Echinococcus granulosus fmrfamide receptor 0.0063 0.0242 0.0242
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0113 0.062
Echinococcus granulosus nAChR subunit 0.0028 0.0079 0.0079
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0743 0.0743
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0011 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0242 0.0242
Echinococcus granulosus nmda type glutamate receptor 0.0139 0.06 0.06
Trypanosoma brucei C-14 sterol reductase, putative 0.0092 0.0381 0.1067
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0028 0.0049
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0028 0.0059
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0216 0.4426
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0089 0.1724
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0049 0.0279
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0057 0.0212 0.0212
Onchocerca volvulus 0.0028 0.0079 0.0071
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Brugia malayi Serotonin receptor 0.0063 0.0242 0.0231
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.0194 0.0194
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0123 0.0117
Schistosoma mansoni hypothetical protein 0.0105 0.0443 0.0443
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0113 0.2227
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0059 0.0059
Echinococcus multilocularis neuropeptide s receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0256 0.025
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0325 0.1483 0.1483
Brugia malayi jmjC domain containing protein 0.0143 0.062 0.0609
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0463 0.1314
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0035 0.0148
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0021 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.0673 0.0663
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.0194 0.0194
Schistosoma mansoni neuropeptide receptor 0.0063 0.0242 0.0242
Echinococcus granulosus jumonji domain containing 1A 0.0014 0.0011 0.0011
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0178 0.0786 0.0786
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0242 0.0242
Echinococcus multilocularis sodium and chloride dependent glycine 0.0361 0.1651 0.1651
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0015 0.0015
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0113 0.0918
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0049 0.0119
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0479 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni jumonji/arid domain-containing protein 0.0053 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Loa Loa (eye worm) hypothetical protein 0.0228 0.1024 0.1019
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0077 0.0071
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0059 0.0048
Echinococcus granulosus transcription factor Dp 1 0.004 0.0132 0.0132
Onchocerca volvulus 0.0036 0.0113 0.0105
Schistosoma mansoni nAChR subunit 0.0024 0.0059 0.0059
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0057 0.0212 0.0212
Echinococcus granulosus peptide allatostatin:somatostatin 0.0063 0.0242 0.0242
Echinococcus granulosus neuropeptide FF receptor 2 0.0063 0.0242 0.0242
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0175 0.0175
Onchocerca volvulus 0.0024 0.0059 0.0052
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0011 0.0005
Schistosoma mansoni growth hormone secretagogue receptor 0.0063 0.0242 0.0242
Schistosoma mansoni hypothetical protein 0.0063 0.0242 0.0242
Echinococcus granulosus tar DNA binding protein 0.0066 0.0256 0.0256
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0092 0.0234
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0194 0.0194
Plasmodium falciparum amino acid transporter, putative 0.0361 0.1651 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0021 0.0039
Echinococcus multilocularis neuropeptide receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0092 0.0086
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0107
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Schistosoma mansoni neuropeptide receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0107
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0269 0.5433
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus multilocularis microtubule associated protein 2 0.2075 0.9753 0.9753
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0089 0.1724
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0063 0.0242 0.0231
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0361 0.1651 0.1651
Brugia malayi Protein kinase domain containing protein 0.0015 0.0015 0.0004
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0049 0.0279
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0111 0.2201
Echinococcus granulosus intermediate filament protein 0.0028 0.0077 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0089 0.0475
Echinococcus multilocularis jumonji domain containing protein 0.0061 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus multilocularis g-protein coupled receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.0242 0.0242
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0747 0.3476 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0216 0.0129
Echinococcus granulosus sodium and chloride dependent glycine 0.0361 0.1651 0.1651
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0361 0.1651 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0049 0.0279
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0135 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0479 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Trypanosoma brucei C-8 sterol isomerase, putative 0.0747 0.3476 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0361 0.1651 0.1642
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0068 0.035
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0021 0.0029
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0216 0.0206
Schistosoma mansoni tyrosine kinase 0.0016 0.0019 0.0019
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0194 0.0183
Echinococcus granulosus nmda type glutamate receptor 0.0098 0.0407 0.0407
Echinococcus granulosus allatostatin A receptor 0.0063 0.0242 0.0242
Brugia malayi RNA binding protein 0.0066 0.0256 0.0245
Loa Loa (eye worm) hypothetical protein 0.0146 0.0634 0.0629
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0049 0.0279
Echinococcus multilocularis glutamate receptor 2 0.0112 0.0475 0.0475
Brugia malayi Bromodomain containing protein 0.0044 0.0151 0.014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0053
Echinococcus multilocularis lysine specific demethylase 5A 0.0053 0.0194 0.0194
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0043 0.0102
Schistosoma mansoni survival motor neuron protein 0.0047 0.0165 0.0165
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0176 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.0194 0.0183
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0176 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Schistosoma mansoni hypothetical protein 0.0044 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0073
Echinococcus multilocularis inositol monophosphatase 1 0.011 0.0463 0.0463
Trichomonas vaginalis inositol monophosphatase, putative 0.011 0.0463 0.9667
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0195 0.0195
Loa Loa (eye worm) jmjC domain-containing protein 0.009 0.037 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Brugia malayi GnHR receptor homolog 0.0063 0.0242 0.0231
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0063 0.0242 0.0242
Schistosoma mansoni Lamin B receptor (ERG24) 0.0092 0.0381 0.0381
Brugia malayi Guanylyl cyclase protein 23 0.0016 0.0019 0.0008
Brugia malayi hypothetical protein 0.0063 0.0242 0.0231
Brugia malayi beta-lactamase family protein 0.0036 0.0113 0.0102
Loa Loa (eye worm) hypothetical protein 0.0033 0.0099 0.0094
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0059 0.0048
Brugia malayi hypothetical protein 0.0024 0.0059 0.0048
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0194 0.0194
Loa Loa (eye worm) jmjC domain-containing protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus multilocularis PHD finger protein rhinoceros 0.0044 0.0151 0.0151
Brugia malayi Cytochrome P450 family protein 0.0022 0.0049 0.0038
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0028 0.0028
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0089 0.0475
Schistosoma mansoni inositol monophosphatase 0.011 0.0463 0.0463
Onchocerca volvulus 0.0127 0.0547 0.054
Brugia malayi hypothetical protein 0.0026 0.0068 0.0058
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0195 0.0867 0.0867
Onchocerca volvulus 0.0063 0.0242 0.0234
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0053 0.0194 0.0194
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) PHD-finger family protein 0.0044 0.0151 0.0145
Echinococcus granulosus lamin dm0 0.0028 0.0077 0.0077
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0194 0.0194
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0113 0.0303
Schistosoma mansoni jumonji domain containing protein 0.0014 0.0011 0.0011
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0068 0.0166
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.1024 0.1024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0059 0.0048
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0014 0.0012 0.0002
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Onchocerca volvulus 0.0016 0.0019 0.0012
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0194 0.0194
Echinococcus multilocularis lamin dm0 0.0028 0.0077 0.0077
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0028 0.0059
Brugia malayi Cytochrome P450 family protein 0.0022 0.0049 0.0038
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0361 0.1651 1
Echinococcus granulosus orexin receptor type 2 0.0063 0.0242 0.0242
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0307 0.0307
Onchocerca volvulus 0.0063 0.0242 0.0234
Brugia malayi hypothetical protein 0.004 0.0135 0.0124
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0479 0.0479
Loa Loa (eye worm) glutamate receptor 1 0.0153 0.0668 0.0663
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0057 0.0212 0.0212
Leishmania major C-8 sterol isomerase-like protein 0.0747 0.3476 1
Brugia malayi hypothetical protein 0.0024 0.0059 0.0048
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.0242 0.0242
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0361 0.1651 0.1651
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0361 0.1651 0.1642
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0012 0.0001
Echinococcus multilocularis nAChR subunit 0.0053 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0127 0.0547 0.0541
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0194 0.0194
Plasmodium falciparum phd finger protein, putative 0.0044 0.0151 0.0851
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0135 0.0135
Brugia malayi MH2 domain containing protein 0.012 0.0511 0.05
Echinococcus multilocularis fmrfamide receptor 0.0063 0.0242 0.0242
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0113 0.0102
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0194 0.0194
Onchocerca volvulus Putative nachr subunit 0.0053 0.0194 0.0186
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0479 0.0473
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0013 0.0015
Schistosoma mansoni loxhd1 0.004 0.0135 0.0135
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0165 0.0157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0361 0.1651 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0028 0.0059
Toxoplasma gondii hypothetical protein 0.0361 0.1651 1
Echinococcus multilocularis nmda type glutamate receptor 0.0139 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0169 0.0743 0.0743
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0216 0.0593
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0747 0.3476 0.3468
Loa Loa (eye worm) hypothetical protein 0.0075 0.0298 0.0292
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0022 0.0049 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0176 0.0176
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0063 0.0242 0.0242
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0113 0.0918
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0028 0.0059
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0165 0.0165
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0195 0.0867 0.0867
Loa Loa (eye worm) hypothetical protein 0.0105 0.0443 0.0437
Loa Loa (eye worm) doublecortin family protein 0.004 0.0135 0.0129
Echinococcus multilocularis geminin 0.0695 0.3231 0.3231
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0127 0.0547 0.0547
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0044 0.0151 0.0151
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0048 0.0853
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0124 0.0113
Echinococcus granulosus atrial natriuretic peptide receptor 0.0016 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0479 1
Onchocerca volvulus 0.0047 0.0165 0.0157
Schistosoma mansoni hypothetical protein 0.0057 0.0212 0.0212
Onchocerca volvulus 0.0063 0.0242 0.0234
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0463 0.9667
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0361 0.1651 0.1646
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0463 0.9667
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus multilocularis JmjC domain containing protein 4 0.0014 0.0011 0.0011
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0049 0.0119
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0242 0.0242
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0195 0.0184
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.0011 0.0011
Echinococcus granulosus g protein coupled receptor 0.0063 0.0242 0.0242
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0361 0.1651 0.1651
Schistosoma mansoni sodium/chloride dependent transporter 0.0361 0.1651 0.1651
Schistosoma mansoni myosin xvIII 0.0063 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0079 0.0079
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0028 0.0059
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Loa Loa (eye worm) hypothetical protein 0.004 0.0135 0.0129
Onchocerca volvulus 0.0036 0.0113 0.0105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0194 0.0183
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0019 0.0008
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0049 0.0279
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0049 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.0194 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Mycobacterium ulcerans beta-lactamase 0.0036 0.0113 0.1483
Echinococcus multilocularis orexin receptor type 2 0.0063 0.0242 0.0242
Onchocerca volvulus 0.0016 0.0019 0.0012
Echinococcus granulosus synaptic vesicular amine transporter 0.02 0.0888 0.0888
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0049 0.0279
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0175 0.0175
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0021 0.0021
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0216 0.1957
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0361 0.1651 0.1651
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0113 0.0918
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0063 0.0242 0.0236
Echinococcus granulosus muscleblind protein 0.0146 0.0634 0.0634
Brugia malayi Cytochrome P450 family protein 0.0031 0.0092 0.0081
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0479 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0028 0.0017
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0014 0.0011 0.001
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0113 0.0918
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0194 0.0183
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0015 0.0015
Echinococcus granulosus glutamate receptor 2 0.0112 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0011 0.0005
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0194 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus multilocularis synaptic vesicular amine transporter 0.02 0.0888 0.0888
Echinococcus multilocularis 0.0022 0.0049 0.0049
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0479 0.0473
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0049 0.0279
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0059 0.0059
Brugia malayi Cation transporter family protein 0.0127 0.0547 0.0537
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Echinococcus multilocularis serotonin receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0057 0.0212 0.0212
Schistosoma mansoni tyrosine kinase 0.0016 0.0019 0.0019
Schistosoma mansoni nAChR subunit 0.0053 0.0194 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0361 0.1651 0.1651
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0123 0.0112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0194 0.0183
Schistosoma mansoni amine GPCR 0.0063 0.0242 0.0242
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.1024 0.1024
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0175 0.0175
Echinococcus granulosus hypothetical protein 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0188
Schistosoma mansoni ap endonuclease 0.0058 0.0216 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0089 0.3235
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0135 0.0135
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0015 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0021 0.0039
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0361 0.1651 0.1646
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Brugia malayi hypothetical protein 0.0361 0.1651 0.1642
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0178 0.0786 0.0786
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0049 0.0279
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0113 0.2227
Schistosoma mansoni hypothetical protein 0.0051 0.0183 0.0183
Brugia malayi cytochrome P450 0.0022 0.0049 0.0038
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0143 0.062 0.062
Loa Loa (eye worm) glutamate receptor 2 0.0153 0.0668 0.0663
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0063 0.0242 0.0242
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0059 0.0059
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0063 0.0242 0.0242
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0195 0.0195
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0008 0.0008
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0059 0.0048
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0479 0.0479
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.0011 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.1332 0.6242 0.6239
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0049 0.0175 0.0175
Echinococcus multilocularis allatostatin A receptor 0.0063 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0028 0.0432
Toxoplasma gondii exonuclease III APE 0.0058 0.0216 0.1252
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0079 0.0079
Brugia malayi RE15519p 0.0063 0.0242 0.0231
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.0242 0.0242
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0028 0.0028
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0053 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.0236
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0171 0.0471
Schistosoma mansoni lipoxygenase 0.0106 0.0443 0.0443
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0077 0.0066
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0175 0.0175
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0256 0.0256
Schistosoma mansoni inositol monophosphatase 0.011 0.0463 0.0463
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0092 0.0243
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0135 0.0756

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) % Inhibition of [125I]-APNEA binding to adenosine A1 receptor of rat brain ChEMBL. 2709373
Ki (binding) nM Displacement of [3H]-N6 -(phenylisopropyl)adenosine (R)-[3H]-PIA from Adenosine A1 receptor of calf brain ChEMBL. 2709373
Ki (binding) = 1.97 nM Affinity for adenosine A1 receptor using [3H]-N6-(phenylisopropyl)adenosine (R)-[3H]-PIA as a radioligand in rat brain. ChEMBL. 2709373

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.