Detailed information for compound 1194043

Basic information

Technical information
  • TDR Targets ID: 1194043
  • Name: 3-[(4-chlorophenyl)sulfonylamino]-N-(pyridin- 2-ylmethyl)propanamide
  • MW: 353.824 | Formula: C15H16ClN3O3S
  • H donors: 2 H acceptors: 4 LogP: 1.22 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NCc1ccccn1)CCNS(=O)(=O)c1ccc(cc1)Cl
  • InChi: 1S/C15H16ClN3O3S/c16-12-4-6-14(7-5-12)23(21,22)19-10-8-15(20)18-11-13-3-1-2-9-17-13/h1-7,9,19H,8,10-11H2,(H,18,20)
  • InChiKey: YTHCTJIATAIHBY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[(4-chlorophenyl)sulfonylamino]-N-(2-pyridylmethyl)propanamide
  • 3-[(4-chlorophenyl)sulfonylamino]-N-(2-pyridylmethyl)propionamide
  • SMR000031683
  • N~3~-[(4-chlorophenyl)sulfonyl]-N~1~-(pyridin-2-ylmethyl)-beta-alaninamide
  • MLS000046074
  • EU-0063612

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0025 0.0017 0.0017
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0045 0.0088 0.2004
Echinococcus granulosus ornithine aminotransferase 0.0138 0.0426 0.0426
Brugia malayi MH2 domain containing protein 0.0035 0.0053 0.0186
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Leishmania major trypanothione reductase 0.0105 0.0306 0.7009
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0102 0.0297 0.0708
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0025 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0038 0.0064 0.1415
Echinococcus multilocularis ornithine aminotransferase 0.0138 0.0426 0.0426
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0112 0.0331 0.7596
Giardia lamblia DINP protein human, muc B family 0.0041 0.0075 0.1671
Echinococcus multilocularis Aminotransferase class III 0.0138 0.0426 0.0426
Mycobacterium ulcerans L-lysine aminotransferase 0.0138 0.0426 0.1088
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0005 0.0005
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0025 0.0017 0.0017
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0017 0.004
Echinococcus granulosus chromobox protein 1 0.0084 0.0231 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Schistosoma mansoni gabp alpha 0.0074 0.0194 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0087 0.0243 0.5554
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0045 0.0088 0.1336
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Trichomonas vaginalis ap endonuclease, putative 0.0087 0.0243 0.0697
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0033 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0022 0.0069
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.034 0.7812
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0058 0.0137 0.3104
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0676 0.238 0.238
Schistosoma mansoni ferritin 0.0052 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0045 0.0088 0.1962
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0075 0.1671
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0075 0.0075
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Onchocerca volvulus 0.0047 0.0097 0.0952
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0138 0.0426 0.1088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0329
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0182 0.066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0182 0.066
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0025 0.0017 0.0322
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0025 0.0017 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Trichomonas vaginalis PIKK family atypical protein kinase 0.014 0.0435 0.1255
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0075 0.0266
Loa Loa (eye worm) hypothetical protein 0.0047 0.0096 0.0346
Echinococcus granulosus thioredoxin glutathione reductase 0.0105 0.0306 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.023 0.0659
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0231 0.0662
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0203 0.0663 0.0663
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0047 0.0096 0.0096
Loa Loa (eye worm) glutathione reductase 0.0105 0.0306 0.1116
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0025 0.0017 0.0017
Onchocerca volvulus 0.0101 0.0293 0.3299
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus cpg binding protein 0.0109 0.0323 0.0323
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0243 0.0809 0.2969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0227 0.065
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0096 0.0344
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0075 0.1671
Echinococcus granulosus zinc finger protein 0.0029 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Leishmania major phosphatidylinositol 3-kinase, putative 0.0047 0.0096 0.216
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0025 0.0017 0.0017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0017 0.0017
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0025 0.0017 0.0219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) MH2 domain-containing protein 0.0518 0.1806 0.6643
Brugia malayi Inositol-1 0.0114 0.034 0.1243
Echinococcus granulosus dna polymerase eta 0.0041 0.0075 0.0075
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.012 0.036 0.1039
Schistosoma mansoni apoferritin-2 0.0052 0.0113 0.0113
Brugia malayi Bromodomain containing protein 0.0046 0.0093 0.0333
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0212 0.0772
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium tuberculosis Probable aminotransferase 0.0969 0.3446 1
Echinococcus multilocularis chromobox protein 1 0.0084 0.0231 0.0231
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0057 0.0057
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0057 0.0986
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0769 0.2717 1
Mycobacterium ulcerans lipase LipD 0.0079 0.0212 0.0458
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.014 0.0435 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.034 0.7812
Echinococcus multilocularis zinc finger protein 0.0029 0.0032 0.0032
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0017 0.004
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0027 0.0022 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0212 0.0299
Schistosoma mansoni smad 0.0035 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0029 0.0595
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0022 0.0069
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0083 0.0083
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0574
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Schistosoma mansoni chromobox protein 0.0084 0.0231 0.0231
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.014 0.0435 0.1255
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0025 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0046 0.0127
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0266 0.089 0.2458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0062 0.0172
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0212 0.4851
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0182 0.0182
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0025 0.0017 0.0322
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Entamoeba histolytica hypothetical protein 0.0038 0.0064 0.1415
Treponema pallidum exodeoxyribonuclease (exoA) 0.0087 0.0243 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0096 0.0271
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0203 0.0663 0.2432
Mycobacterium tuberculosis Probable reductase 0.0239 0.0793 0.2172
Schistosoma mansoni apoferritin-2 0.0052 0.0113 0.0113
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Schistosoma mansoni hypothetical protein 0.0243 0.0809 0.0809
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) fli-1 protein 0.0225 0.0741 0.2719
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Schistosoma mansoni inositol monophosphatase 0.0114 0.034 0.034
Schistosoma mansoni Smad4 0.0035 0.0053 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0227 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0574
Brugia malayi F/Y-rich N-terminus family protein 0.0034 0.005 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0256 0.0736
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0017 0.004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0057 0.1256
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0505 0.176 0.5025
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0075 0.021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Onchocerca volvulus 0.0079 0.0212 0.2333
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0212 0.0458
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis ferritin 0.0052 0.0113 0.0113
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0138 0.0426 0.1088
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0057 0.1256
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.014 0.0435 0.0435
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Echinococcus multilocularis expressed protein 0.0025 0.0017 0.0017
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.014 0.0435 0.0435
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Schistosoma mansoni microtubule-associated protein tau 0.2774 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Brugia malayi hypothetical protein 0.0169 0.0539 0.1974
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0212 0.0773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0096 0.0271
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0112 0.0331 0.7596
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0138 0.0426 0.1088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0055 0.0124 0.0124
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0138 0.0426 0.1558
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.014 0.0435 0.0435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis esterase, putative 0.0079 0.0212 0.0609
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0017 0.0017
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0027 0.0022 0.0435
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0203 0.0663 0.2431
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0029 0.0595
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi TAR-binding protein 0.0071 0.0182 0.066
Mycobacterium ulcerans hypothetical protein 0.0079 0.0212 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0057 0.1256
Onchocerca volvulus 0.0048 0.0099 0.0987
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0075 0.0075
Echinococcus granulosus fetal alzheimer antigen falz 0.0033 0.0045 0.0045
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0194 0.0194
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0075 0.0075
Schistosoma mansoni ferritin 0.0052 0.0113 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0047 0.0097 0.0097
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0212 0.0458
Loa Loa (eye worm) hypothetical protein 0.0085 0.0235 0.0857
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0087 0.0243 0.5554
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0037 0.0037
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0025 0.0017 0.0322
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.0322 0.7549
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0003 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0057 0.0158
Mycobacterium leprae Probable lipase LipE 0.0079 0.0212 0.0299
Brugia malayi hypothetical protein 0.0231 0.0765 0.2808
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0025 0.0017 0.0017
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0266 0.089 0.2458
Schistosoma mansoni DNA helicase recq5 0.0021 0.0003 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0055 0.0124 0.0124
Schistosoma mansoni cellular tumor antigen P53 0.0156 0.0492 0.0492
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.014 0.0435 1
Leishmania major hypothetical protein, conserved 0.0079 0.0212 0.4851
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0212 0.0212
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0182 0.0182
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0075 0.0053
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0057 0.1283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0331 0.0952
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0045 0.0088 0.0088
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0114 0.034 0.532
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0025 0.0017 0.0017
Echinococcus multilocularis Smad4 0.0035 0.0053 0.0053
Schistosoma mansoni DNA helicase recq1 0.0021 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0212 0.4851
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0025 0.0017 0.0017
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0025 0.0017 0.0329
Brugia malayi Ets-domain containing protein 0.0074 0.0194 0.0704
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0114 0.034 0.0836
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma brucei unspecified product 0.0041 0.0075 0.1671
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0138 0.0426 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Echinococcus multilocularis expressed protein 0.0052 0.0113 0.0113
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0194 0.0704
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Schistosoma mansoni smad1 5 8 and 0.0035 0.0053 0.0053
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0057 0.0855
Mycobacterium tuberculosis Conserved protein 0.0079 0.0212 0.0458
Giardia lamblia Hypothetical protein 0.0025 0.0017 0.0322
Echinococcus granulosus expressed protein 0.0052 0.0113 0.0113
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0025 0.0017 0.0017
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0025 0.0017 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0049 0.0049
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0231 0.084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium tuberculosis Conserved protein 0.0079 0.0212 0.0458
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.014 0.0435 0.1592
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0021 0.0021
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0087 0.0243 0.5528
Toxoplasma gondii thioredoxin reductase 0.0105 0.0306 0.4773
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0025 0.0017 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0114 0.034 0.7684
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0025 0.0017 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0075 0.1671
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.014 0.0435 1
Mycobacterium ulcerans acetylornithine aminotransferase 0.0138 0.0426 0.1088
Trichomonas vaginalis ubiquitin specific protease, putative 0.0025 0.0017 0.004
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.014 0.0435 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0053 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.023 0.0659
Brugia malayi Fli-1 protein 0.0225 0.0741 0.2718
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0216 0.071 0.071
Loa Loa (eye worm) hypothetical protein 0.0769 0.2717 1
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0075 0.1671
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0267 0.0768
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni DNA polymerase eta 0.0041 0.0075 0.0075
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0243 0.0809 0.0809
Echinococcus multilocularis inositol monophosphatase 1 0.0114 0.034 0.034
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0573
Brugia malayi MH1 domain containing protein 0.0035 0.0053 0.0186
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0047 0.0096 0.216
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0033 0.0045 0.0045
Brugia malayi MH1 domain containing protein 0.0035 0.0053 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0022 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0022 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0212 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0243 0.0809 0.0809
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Entamoeba histolytica hypothetical protein 0.0038 0.0064 0.1415
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Leishmania major hypothetical protein, conserved 0.0109 0.0322 0.7389
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0212 0.0458
Brugia malayi PHD-finger family protein 0.0036 0.0055 0.0194
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.011
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0114 0.034 0.7812
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0212 0.0609
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0212 0.0212
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0064 0.0064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0138 0.0426 0.1088
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0102 0.0297 0.0553
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0049 0.0735
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0212 0.0609
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0969 0.3446 1
Plasmodium falciparum ornithine aminotransferase 0.0138 0.0426 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.0322 0.7389
Loa Loa (eye worm) CHromoDomain protein family member 0.0022 0.0005 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.034 0.098
Schistosoma mansoni cpg binding protein 0.0109 0.0323 0.0323
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Brugia malayi hypothetical protein 0.0109 0.0322 0.1176
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0212 0.4784
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0182 0.0182
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0083 0.0083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.0266
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0203 0.0663 0.0663
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0182 0.066
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.014 0.0435 1
Brugia malayi hypothetical protein 0.0038 0.0064 0.0225
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0194 0.0194
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0025 0.0017 0.0017
Echinococcus multilocularis GPCR, family 2 0.0243 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0079 0.0212 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0138 0.0426 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Onchocerca volvulus 0.0156 0.0492 0.5673
Echinococcus granulosus dna polymerase kappa 0.0041 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0033 0.0087
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0045 0.0088 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0182 0.0182
Toxoplasma gondii non-specific serine/threonine protein kinase 0.003 0.0033 0.047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0045 0.0088 0.1962
Plasmodium falciparum ubiquitin specific protease, putative 0.0025 0.0017 0.0329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0025 0.0017 0.0052
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0203 0.0663 0.0663
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0022 0.0435
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0045 0.0088 0.0313
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0243 0.0809 0.0809
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.034 0.7812
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0053 0.0187
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Schistosoma mansoni cpg binding protein 0.0109 0.0323 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0022 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0027 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0096 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0096 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0331 0.0952
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0059 0.0162
Echinococcus multilocularis chromobox protein 1 0.0084 0.0231 0.0231
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Echinococcus granulosus tumor protein p63 0.1067 0.3801 0.3801
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Brugia malayi ubiquitin specific protease 14 0.0025 0.0017 0.0051
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0047 0.0096 0.216
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0138 0.0426 0.0426
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0231 0.0662
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0239 0.0793 0.2172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Loa Loa (eye worm) thioredoxin reductase 0.0105 0.0306 0.1116
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1721 0.6174 0.6174
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0105 0.0306 0.0734
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0022 0.0296
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0075 0.0075
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0138 0.0426 0.0939
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0243 0.0809 0.0809
Brugia malayi beta-lactamase family protein 0.0079 0.0212 0.0772
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0017 0.0017
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0212 0.0458
Plasmodium falciparum glutathione reductase 0.0036 0.0057 0.1283
Brugia malayi beta-lactamase 0.0079 0.0212 0.0772
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0182 0.0182
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0025 0.0017 0.0017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.002 0.005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0025 0.0017 0.0329
Plasmodium falciparum glutathione reductase 0.0105 0.0306 0.7161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0331 0.0952
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0025 0.0017 0.0052
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0025 0.0017 0.0017
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0087 0.0243 0.5675
Schistosoma mansoni hypothetical protein 0.0962 0.3417 0.3417
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0087 0.0243 0.0548
Schistosoma mansoni zinc finger protein 0.0029 0.0032 0.0032
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0017 0.0017
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0087 0.0243 0.5554
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0025 0.0017 0.0322
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0047 0.0096 0.216
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0045 0.0088 0.1962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0573
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0059 0.0162
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0017 0.0017
Brugia malayi CHD4 protein 0.0022 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0025 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.014 0.0435 0.1255
Plasmodium vivax ornithine aminotransferase, putative 0.0138 0.0426 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0057 0.1256
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0096 0.0951
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0052 0.0113 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0075 0.0053
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Toxoplasma gondii ubiquitin-specific protease USP4 0.0025 0.0017 0.0219
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0057 0.1256
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0182 0.0182
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.014 0.0435 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0022 0.0005 0.0005
Trichomonas vaginalis ferritin, putative 0.0052 0.0113 0.0319
Echinococcus granulosus inositol monophosphatase 1 0.0114 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0079 0.0212 0.0773
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0212 0.0458
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0057 0.1256
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0087 0.0243 0.0885
Schistosoma mansoni ets-related 0.0225 0.0741 0.0741
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0059 0.0162
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0057 0.1256
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0025 0.0017 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0057 0.0986
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0769 0.2717 1
Trichomonas vaginalis ap endonuclease, putative 0.0087 0.0243 0.0697
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0087 0.0243 0.5038
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0212 0.0458
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0266 0.089 0.2332
Mycobacterium ulcerans bacterioferritin BfrB 0.0052 0.0113 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0203 0.0663 0.0663
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Brugia malayi latrophilin 2 splice variant baaae 0.0526 0.1834 0.6745
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Echinococcus granulosus histone lysine methyltransferase setb 0.0055 0.0124 0.0124
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0025 0.0017 0.0017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0225 0.0743 0.2729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Brugia malayi Heterochromatin protein 1 0.0084 0.0231 0.084
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0057 0.1256
Schistosoma mansoni ferritin light chain 0.0052 0.0113 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.023 0.0659
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0016 0.0048
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0045 0.0088 0.1962
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0212 0.0458
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0057 0.0057
Schistosoma mansoni ferritin 0.0052 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0087 0.0243 0.5554
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0057 0.1256
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0208 0.0208
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.014 0.0435 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0025 0.0017 0.0017
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium tuberculosis Conserved protein 0.0079 0.0212 0.0458
Loa Loa (eye worm) hypothetical protein 0.0526 0.1834 0.6746
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0025 0.0017 0.0017
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0025 0.0017 0.0017
Plasmodium vivax thioredoxin reductase, putative 0.0105 0.0306 0.7065
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0025 0.0017 0.0017
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0045 0.0088 0.0246
Brugia malayi Latrophilin receptor protein 2 0.0243 0.0809 0.2969
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0203 0.0663 0.0663
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0138 0.0426 0.1088
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0027 0.0022 0.0435
Trichomonas vaginalis ubiquitin specific protease, putative 0.0025 0.0017 0.004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Echinococcus granulosus bloom syndrome protein 0.0021 0.0003 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0022 0.0071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0025 0.0017 0.0219
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0231 0.0765 0.2808
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0196 0.0637 1
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0969 0.3446 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0239 0.0793 0.2041
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0057 0.0855
Brugia malayi Pre-SET motif family protein 0.0225 0.0743 0.2729
Schistosoma mansoni ferritin light chain 0.0052 0.0113 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0096 0.0272
Giardia lamblia DUB-1 0.0025 0.0017 0.0322
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.0373
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Plasmodium falciparum ubiquitin specific protease, putative 0.0025 0.0017 0.0329
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0156 0.0492 0.1804
Plasmodium vivax ataxin-2 like protein, putative 0.0109 0.0322 0.7466
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Echinococcus granulosus smad 0.0035 0.0053 0.0053
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0212 0.0458
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Loa Loa (eye worm) transcription factor SMAD2 0.0518 0.1806 0.6643
Brugia malayi hypothetical protein 0.0025 0.0017 0.0051
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0057 0.1256
Mycobacterium ulcerans hypothetical protein 0.0969 0.3446 1
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0049 0.0049
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0025 0.0017 0.0017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0021 0.0021
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0045 0.0088 0.0246
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0676 0.238 0.238
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Brugia malayi glutathione reductase 0.0105 0.0306 0.1116
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Toxoplasma gondii hypothetical protein 0.0025 0.0017 0.0219
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0138 0.0426 1
Plasmodium falciparum thioredoxin reductase 0.0036 0.0057 0.1283
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0003 0.0000000005569
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0014 0.0032
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0025 0.0017 0.0017
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0087 0.0243 0.0548
Trypanosoma brucei unspecified product 0.0028 0.0029 0.0595
Echinococcus granulosus Aminotransferase class III 0.0138 0.0426 0.0426
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Loa Loa (eye worm) hypothetical protein 0.0109 0.0322 0.1177
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0087 0.0243 0.0243
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0075 0.0053
Schistosoma mansoni hypothetical protein 0.0025 0.0017 0.0017
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0969 0.3446 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni ap endonuclease 0.0087 0.0243 0.0243
Toxoplasma gondii exonuclease III APE 0.0087 0.0243 0.3782
Trichomonas vaginalis helicase, putative 0.0023 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0079 0.0212 0.0773
Mycobacterium tuberculosis Probable oxidoreductase 0.0266 0.089 0.2458
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0243 0.0809 0.2969
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) beta-lactamase 0.0079 0.0212 0.0773
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0045 0.0088 0.0312
Loa Loa (eye worm) phosphatidylinositol 3 0.014 0.0435 0.1592
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0045 0.0088 0.0088
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0057 0.02
Loa Loa (eye worm) Smad1 0.0035 0.0053 0.0187
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0025 0.0017 0.0017
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0025 0.0017 0.0017
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0052 0.0113 0.0164
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.0103 0.0103
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0045 0.0088 0.1732
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0096 0.0271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0021 0.0021
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0053 0.0053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0203 0.0663 0.0663
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0155 0.0561
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0053 0.0053
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Trypanosoma cruzi trypanothione reductase, putative 0.0105 0.0306 0.7009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0017 0.0017
Trypanosoma brucei unspecified product 0.0028 0.0029 0.0595
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0574
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni cpg binding protein 0.0101 0.0293 0.0293
Loa Loa (eye worm) inositol-1 0.0114 0.034 0.1244
Echinococcus granulosus dnaJ subfamily B 0.0962 0.3417 0.3417
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0025 0.0017 0.0017
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Trypanosoma brucei trypanothione reductase 0.0105 0.0306 0.7009
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0138 0.0426 0.1088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0057 0.0158
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0075 0.1671
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0969 0.3446 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi beta-lactamase family protein 0.0079 0.0212 0.0772
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0124 0.0448
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi target of rapamycin kinase 3 0.0112 0.0331 0.7596
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0075 0.0266
Schistosoma mansoni hypothetical protein 0.0025 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0097
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0096 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0037 0.0059 0.0209
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0052 0.0113 0.1508
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Brugia malayi chromobox protein homolog 3 0.0047 0.0096 0.0345
Echinococcus granulosus ferritin 0.0052 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi MH2 domain containing protein 0.0035 0.0053 0.0186
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Brugia malayi Pre-SET motif family protein 0.0034 0.0049 0.0172
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0057 0.1283
Onchocerca volvulus 0.0037 0.0059 0.051
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Loa Loa (eye worm) latrophilin receptor protein 2 0.0243 0.0809 0.2969
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0025 0.0017 0.0017
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Loa Loa (eye worm) hypothetical protein 0.0079 0.0212 0.0773
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0025 0.0017 0.0017
Echinococcus multilocularis ubiquitin specific protease 41 0.0025 0.0017 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0022 0.0022
Echinococcus multilocularis cpg binding protein 0.0109 0.0323 0.0323
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0109 0.031
Trichomonas vaginalis set domain proteins, putative 0.0256 0.0855 0.2476
Entamoeba histolytica hypothetical protein 0.0025 0.0017 0.0322
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Echinococcus multilocularis tumor protein p63 0.1067 0.3801 0.3801
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.014 0.0435 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Schistosoma mansoni hypothetical protein 0.0526 0.1834 0.1834
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0022 0.0022
Echinococcus multilocularis dnaJ subfamily B 0.0962 0.3417 0.3417
Echinococcus granulosus ubiquitin specific peptidase c family 0.0025 0.0017 0.0017
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0075 0.0266
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0022 0.0022
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0075 0.0075
Onchocerca volvulus 0.0079 0.0212 0.2333
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0239 0.0793 0.2172
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0329
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0025 0.0017 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0029 0.0595
Loa Loa (eye worm) CXXC zinc finger family protein 0.0101 0.0293 0.1071
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0138 0.0426 0.0939
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0025 0.0017 0.0017
Brugia malayi exodeoxyribonuclease III family protein 0.0087 0.0243 0.0884
Entamoeba histolytica hypothetical protein 0.0038 0.0064 0.1415
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Giardia lamblia GTOR 0.014 0.0435 1
Toxoplasma gondii LsmAD domain-containing protein 0.0109 0.0322 0.5032
Brugia malayi Smad1 0.0035 0.0053 0.0186
Onchocerca volvulus 0.0256 0.0855 1
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.0765 0.0765
Schistosoma mansoni bromodomain containing protein 0.0082 0.0224 0.0224
Plasmodium vivax SET domain protein, putative 0.0034 0.0049 0.0801
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0025 0.0017 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0212 0.4851
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0053 0.0053
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0025 0.0017 0.0017
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.034 0.098
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0239 0.0793 0.2172
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0075 0.0053
Loa Loa (eye worm) RNA binding protein 0.0071 0.0182 0.066
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0239 0.0793 0.2172
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0169 0.0539 0.1975
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0243 0.0809 0.0809
Onchocerca volvulus 0.0079 0.0212 0.2333
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Schistosoma mansoni ferritin 0.0052 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0243 0.0809 0.0809
Mycobacterium ulcerans beta-lactamase 0.0079 0.0212 0.0458
Loa Loa (eye worm) hypothetical protein 0.0057 0.0133 0.0481
Brugia malayi Calcitonin receptor-like protein seb-1 0.0769 0.2717 1
Schistosoma mansoni peptidase 0.0025 0.0017 0.0017
Echinococcus granulosus tar DNA binding protein 0.0071 0.0182 0.0182
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0025 0.0017 0.0017
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0331 0.0952
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Mycobacterium ulcerans bacterioferritin BfrA 0.0052 0.0113 0.0164
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.0765 0.0765
Loa Loa (eye worm) hypothetical protein 0.0046 0.0093 0.0334
Echinococcus multilocularis ornithine aminotransferase 0.0138 0.0426 0.0426
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.0322 0.7549
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Loa Loa (eye worm) hypothetical protein 0.0079 0.0212 0.0773
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0097 0.0345
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0025 0.0017 0.0051
Brugia malayi MH2 domain containing protein 0.0518 0.1806 0.6643
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0573
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.034 0.7812
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0138 0.0426 0.6666
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0047 0.0096 0.216
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0025 0.0017 0.0017
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0047 0.0096 0.216
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0105 0.0306 0.0306
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Trypanosoma brucei PAB1-binding protein , putative 0.0109 0.0322 0.7389
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0066 0.0166 0.3783
Trichomonas vaginalis inositol monophosphatase, putative 0.0114 0.034 0.098
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0045 0.0088 0.0312
Echinococcus granulosus Smad4 0.0035 0.0053 0.0053
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0109 0.031
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0087 0.0243 0.5554
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0096 0.0272
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0022 0.0435
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0219
Brugia malayi CXXC zinc finger family protein 0.0101 0.0293 0.107
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.005
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0212 0.0609
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Onchocerca volvulus 0.0169 0.0539 0.6224
Plasmodium falciparum thioredoxin reductase 0.0105 0.0306 0.7161
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0075 0.1671
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0025 0.0017 0.0017
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0045 0.0088 0.0313
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0055 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0025 0.0017 0.0017
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0331 0.0952
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0087 0.0243 0.5554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0045 0.0088 0.1962
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0053 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Entamoeba histolytica protein kinase rad3, putative 0.0027 0.0022 0.0435
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0138 0.0426 0.1088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0025 0.0017 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0212 0.0609
Schistosoma mansoni hypothetical protein 0.0049 0.0103 0.0103
Brugia malayi RNA binding protein 0.0071 0.0182 0.066
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Schistosoma mansoni inositol monophosphatase 0.0114 0.034 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Echinococcus granulosus chromobox protein 1 0.0084 0.0231 0.0231
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0057 0.0057
Echinococcus multilocularis smad 0.0035 0.0053 0.0053
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0212 0.0609
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0025 0.0017 0.0017
Brugia malayi Ets-domain containing protein 0.0074 0.0194 0.0704
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0025 0.0017 0.0017
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0017 0.0051
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0025 0.0017 0.0329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus multilocularis microtubule associated protein 2 0.2774 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0059 0.0162
Loa Loa (eye worm) hypothetical protein 0.0079 0.0212 0.0773
Echinococcus multilocularis dna polymerase eta 0.0041 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Schistosoma mansoni hypothetical protein 0.0038 0.0064 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Schistosoma mansoni ap endonuclease 0.0087 0.0243 0.0243
Mycobacterium tuberculosis Probable dehydrogenase 0.0239 0.0793 0.2172
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0075 0.021
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0208 0.0208
Treponema pallidum bacterioferrin (TpF1) 0.0052 0.0113 0.2992
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.0322 0.7389
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0025 0.0017 0.0017
Toxoplasma gondii ABC1 family protein 0.0079 0.0212 0.3303
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0022 0.0071
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0059 0.0162
Leishmania major DNA polymerase kappa, putative 0.0041 0.0075 0.1671
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0212 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0017
Schistosoma mansoni fkbp-rapamycin associated protein 0.0027 0.0022 0.0022
Echinococcus granulosus ubiquitin specific protease 41 0.0025 0.0017 0.0017
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Schistosoma mansoni chromobox protein 0.0084 0.0231 0.0231
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0075 0.1671
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0243 0.0809 0.0809
Toxoplasma gondii target of rapamycin (TOR), putative 0.0104 0.0304 0.4752
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Brugia malayi Bromodomain containing protein 0.0096 0.0275 0.1003
Brugia malayi Thioredoxin reductase 0.0105 0.0306 0.1116
Brugia malayi hypothetical protein 0.0071 0.0181 0.0658
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0138 0.0426 0.0939
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0104 0.0304 0.0876
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0025 0.0017 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0022 0.0055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0059 0.0162
Leishmania major DNA polymerase eta, putative 0.0041 0.0075 0.1671
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0203 0.0663 0.0663
Trichomonas vaginalis ubiquitin specific protease, putative 0.0025 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0052
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0047 0.0096 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0059 0.0162
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0212 0.0212
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.0103 0.0103
Loa Loa (eye worm) histone methyltransferase 0.0033 0.0043 0.015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0025 0.0017 0.0017
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0047 0.0096 0.0096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0025 0.0017 0.0329
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0109 0.1106
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0025 0.0017 0.0017
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Schistosoma mansoni smad1 5 8 and 0.0035 0.0053 0.0053
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0025 0.0017 0.0017
Echinococcus granulosus GPCR family 2 0.0243 0.0809 0.0809
Schistosoma mansoni smad1 5 8 and 0.0035 0.0053 0.0053
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0059 0.0162
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0025 0.0017 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.02 0.0574
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0017 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0017 0.004
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0017 0.0322
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0017 0.0322
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0003 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0025 0.0017 0.0322
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0087 0.0243 0.0243
Plasmodium vivax glutathione reductase, putative 0.0105 0.0306 0.7065
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0064 0.0064
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0057 0.1256
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.004
Schistosoma mansoni survival motor neuron protein 0.0047 0.0097 0.0097
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0025 0.0017 0.0017

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 0.3696 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.7079 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 3.6964 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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