Detailed information for compound 1330636

Basic information

Technical information
  • TDR Targets ID: 1330636
  • Name: 93361-93-4
  • MW: 369.434 | Formula: C20H19NO4S
  • H donors: 3 H acceptors: 4 LogP: 0.5 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc2c(c1)Sc1cccc3c1C(C2)CNC3.OC(=O)/C=C\C(=O)O
  • InChi: 1S/C16H15NS.C4H4O4/c1-2-6-14-11(4-1)8-13-10-17-9-12-5-3-7-15(18-14)16(12)13;5-3(6)1-2-4(7)8/h1-7,13,17H,8-10H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
  • InChiKey: AQQSBMUTIZCLBU-BTJKTKAUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1H-(1)BENZOTHIEPINO(4,3,2-de)ISOQUINOLINE, 2,3,12,12a-TETRAHYDRO-, (Z)-2-BUTENED
  • 1H-(1)Benzothiepino(4,3,2-de)isoquinoline, 2,3,12,12a-tetrahydro-, (Z)-2-butenedioate (1:1)
  • 2,3,12,12a-Tetrahydro-1H-(1)benzothiepino(2,3,4-ed)isoquinoline hydrogen maleate
  • 2,3,12,12a-tetrahydro-1H-[1]benzothiepino[4,3,2-de]isoquinoline
  • MLS000705798
  • SMR000224835

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens trace amine associated receptor 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis sex peptide receptor trace amine associated receptor 1 339 aa 281 aa 17.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum cysteine proteinase falcipain 1 0.0121 0.0586 0.5417
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0074 0.0132
Leishmania major hypothetical protein, conserved 0.0035 0.0102 0.0176
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0028 0.006 0.0048
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Loa Loa (eye worm) hypothetical protein 0.0253 0.133 0.1372
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.02 0.0475
Loa Loa (eye worm) hypothetical protein 0.0068 0.0289 0.0298
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.02 0.0475
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0027 0.0054 0.0083
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0088 0.0402 0.2252
Onchocerca volvulus Cathepsin L homolog 0.0209 0.1081 0.2591
Onchocerca volvulus 0.0058 0.0233 0.0519
Schistosoma mansoni smad 0.006 0.0241 0.0228
Schistosoma mansoni hypothetical protein 0.1789 1 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0798 0.0785
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0053 0.02 0.1436
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0074 0.006
Loa Loa (eye worm) inositol-1 0.0041 0.0135 0.0139
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0028 0.006 0.0168
Onchocerca volvulus 0.003 0.0074 0.0132
Loa Loa (eye worm) hypothetical protein 0.0068 0.0289 0.0298
Trypanosoma cruzi cysteine proteinase, putative 0.0121 0.0586 0.1146
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0035 0.0102 0.0821
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0111 0.0476
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0053 0.02 0.0475
Mycobacterium ulcerans beta-lactamase 0.0263 0.139 0.5033
Onchocerca volvulus 0.0035 0.0102 0.0198
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0135 0.0489
Trichomonas vaginalis set domain proteins, putative 0.0747 0.4117 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0206
Brugia malayi fibroinase precursor 0.0053 0.02 0.0192
Loa Loa (eye worm) hypothetical protein 0.0046 0.0161 0.0167
Entamoeba histolytica cysteine protease, putative 0.0053 0.02 0.1739
Brugia malayi beta-lactamase family protein 0.0263 0.139 0.1421
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0135 0.0243
Schistosoma mansoni cathepsin F (C01 family) 0.0209 0.1081 0.1069
Loa Loa (eye worm) hypothetical protein 0.0516 0.2814 0.2902
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Schistosoma mansoni smad1 5 8 and 0.006 0.0241 0.0228
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0042 0.0045
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0058 0.023 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0035 0.0102 0.0105
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0133 0.0119
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0263 0.139 0.1433
Echinococcus granulosus chromobox protein 1 0.0071 0.0302 0.0289
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0088 0.0402 0.0388
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0074 0.006
Echinococcus granulosus TGF beta signal transducer SmadC 0.006 0.0241 0.0228
Schistosoma mansoni hypothetical protein 0.0035 0.0099 0.0086
Plasmodium vivax serine-repeat antigen (SERA) 0.0053 0.02 0.1436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.02 0.0475
Brugia malayi MH1 domain containing protein 0.0033 0.009 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0074 0.0062
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0074 0.0132
Toxoplasma gondii exonuclease III APE 0.0174 0.0886 0.3175
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0014 0.0128
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0033 0.0177
Plasmodium falciparum serine repeat antigen 9 0.0053 0.02 0.1845
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.002 0.0007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0209 0.1081 0.1115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.02 0.0475
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.006 0.0093
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0021 0.002 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0102 0.073
Schistosoma mansoni neutral sphingomyelinase 0.0035 0.0102 0.0088
Leishmania major trypanothione reductase 0.0124 0.06 0.1175
Brugia malayi cathepsin L-like precursor 0.014 0.0695 0.0704
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0028 0.006 0.0137
Schistosoma mansoni nocturnin 0.0035 0.0102 0.0088
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0043 0.0145 0.0154
Toxoplasma gondii cathepsin CPC1 0.0053 0.02 0.0676
Echinococcus granulosus lamin 0.0058 0.0233 0.0219
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0043 0.0145 0.1212
Brugia malayi Cathepsin L-like precursor 0.0209 0.1081 0.1103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0161 0.0152
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Trypanosoma cruzi trypanothione reductase, putative 0.0124 0.06 0.1175
Schistosoma mansoni cathepsin F (C01 family) 0.0209 0.1081 0.1069
Toxoplasma gondii preprocathepsin c precursor, putative 0.0053 0.02 0.0676
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0028 0.006 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.1379 0.3343
Brugia malayi Latrophilin receptor protein 2 0.0117 0.0564 0.0568
Echinococcus granulosus neuropeptide s receptor 0.0462 0.2512 0.2501
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0028 0.006 0.0219
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0054 0.0056
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0053 0.02 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0127 0.0299
Loa Loa (eye worm) hypothetical protein 0.0263 0.139 0.1433
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.0777 0.153
Giardia lamblia Cathepsin B precursor 0.0053 0.02 0.1868
Echinococcus multilocularis cysteine protease 0.0209 0.1081 0.1069
Brugia malayi hypothetical protein 0.1018 0.5646 0.5817
Mycobacterium tuberculosis Probable esterase LipL 0.0263 0.139 0.1478
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0147
Trypanosoma brucei trypanothione reductase 0.0124 0.06 0.1175
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0226 0.118 0.1168
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0043 0.0145 0.0262
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0021 0.002 0.0039
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1683 0.9401 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.0564 0.0581
Schistosoma mansoni cathepsin B (C01 family) 0.0053 0.02 0.0186
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0127 0.062 0.1215
Giardia lamblia Cathepsin L precursor 0.0053 0.02 0.1868
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0135 0.0243
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0031 0.0081 0.0069
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.02 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0074 0.0062
Entamoeba histolytica cysteine proteinase 1, putative 0.0121 0.0586 0.5357
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0196 0.1008 0.2441
Onchocerca volvulus 0.0209 0.1081 0.2591
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0035 0.0102 0.0237
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0028 0.006 0.0219
Loa Loa (eye worm) hypothetical protein 0.005 0.0186 0.0192
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0333 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0586 0.1415
Mycobacterium ulcerans aldehyde dehydrogenase 0.0506 0.2761 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.047 0.0457
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0161 0.0296
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0208 0.1074 0.1095
Plasmodium falciparum DNase I-like protein, putative 0.0035 0.0102 0.0939
Leishmania major aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0102 0.0822
Echinococcus granulosus beta LACTamase domain containing family member 0.0263 0.139 0.1378
Schistosoma mansoni hypothetical protein 0.0028 0.006 0.0047
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0263 0.139 0.1378
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0174 0.0886 0.3209
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0105
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0145 0.0135
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0028 0.006 0.0435
Trypanosoma cruzi cysteine peptidase, putative 0.0209 0.1081 0.2139
Echinococcus granulosus tumor protein p63 0.0706 0.3886 0.3877
Echinococcus granulosus synaptojanin 1 0.0035 0.0102 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Schistosoma mansoni hypothetical protein 0.0036 0.0107 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0068 0.007
Schistosoma mansoni ap endonuclease 0.0174 0.0886 0.0873
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0074 0.0132
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0043 0.0145 0.1041
Trypanosoma cruzi cysteine protease, putative 0.0121 0.0586 0.1146
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0035 0.0102 0.0821
Plasmodium falciparum serine repeat antigen 7 0.0053 0.02 0.1845
Echinococcus granulosus ferritin 0.0028 0.0059 0.0045
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0196 0.1008 0.0996
Onchocerca volvulus 0.0049 0.0177 0.0382
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0206
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0279 0.0531
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0064
Loa Loa (eye worm) hypothetical protein 0.0088 0.0398 0.0411
Plasmodium falciparum phd finger protein, putative 0.0029 0.0068 0.063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0074 0.0076
Echinococcus multilocularis deoxyribonuclease 1 2 0.0035 0.0102 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0053 0.02 0.0475
Schistosoma mansoni inositol monophosphatase 0.0041 0.0135 0.0121
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.006 0.0047
Schistosoma mansoni aldehyde dehydrogenase 0.0506 0.2761 0.2751
Echinococcus granulosus snurportin 1 0.062 0.3405 0.3396
Trypanosoma brucei hypothetical protein, conserved 0.0263 0.139 0.2757
Plasmodium falciparum serine repeat antigen 1 0.0053 0.02 0.1845
Brugia malayi PHD-finger family protein 0.0029 0.0068 0.0056
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.006 0.0093
Echinococcus granulosus cysteine protease 0.0121 0.0586 0.0573
Plasmodium falciparum thioredoxin reductase 0.0043 0.0145 0.1337
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0028 0.006 0.0168
Entamoeba histolytica cysteine protease, putative 0.0053 0.02 0.1739
Loa Loa (eye worm) hypothetical protein 0.0058 0.0233 0.024
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0174 0.0886 0.0873
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0798 0.0785
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Brugia malayi hypothetical protein 0.0081 0.0359 0.0356
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0177 0.0182
Trichomonas vaginalis penicillin-binding protein, putative 0.0263 0.139 0.3369
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.002 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Echinococcus granulosus cathepsin L 0.0121 0.0586 0.0573
Onchocerca volvulus 0.0023 0.0033 0.0031
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0174 0.0886 0.0873
Brugia malayi MH2 domain containing protein 0.006 0.0241 0.0235
Echinococcus multilocularis mothers against decapentaplegic 6 0.0027 0.0054 0.004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0074 0.0062
Giardia lamblia Cathepsin B precursor 0.0053 0.02 0.1868
Schistosoma mansoni ferritin 0.0028 0.0059 0.0045
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.0307 0.0303
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0042 0.0057
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0279 0.0273
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0068 0.0054
Brugia malayi Cathepsin L-like precursor 0.014 0.0695 0.0704
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0028 0.006 0.0047
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Brugia malayi cathepsin Z-like cysteine proteinase 0.0053 0.02 0.0192
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0053 0.02 0.1436
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0121 0.0586 0.0573
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0028 0.006 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0035 0.0102 0.0237
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0461 0.0448
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.02 0.0192
Trichomonas vaginalis glutathione reductase, putative 0.0043 0.0145 0.0342
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0033 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0021
Onchocerca volvulus 0.0209 0.1081 0.2591
Plasmodium falciparum thioredoxin reductase 0.0124 0.06 0.5549
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0021 0.002 0.0021
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0053 0.02 0.0192
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0174 0.0886 0.1748
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0074 0.006
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0058 0.023 0.0245
Schistosoma mansoni ferritin light chain 0.0028 0.0059 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0074 0.006
Entamoeba histolytica hypothetical protein 0.0047 0.0169 0.1454
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0177 0.0163
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0074 0.006
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0043 0.0145 0.0262
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0177 0.0163
Loa Loa (eye worm) hypothetical protein 0.014 0.0695 0.0717
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0028 0.006 0.0064
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0053 0.02 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.02 0.0475
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0033 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0028 0.006 0.0219
Echinococcus granulosus cathepsin l1 0.0209 0.1081 0.1069
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0143 0.0147
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0042 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0102 0.0237
Plasmodium vivax vivapain-3 0.0121 0.0586 0.4215
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0414 0.0401
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0035 0.0102 0.073
Trypanosoma cruzi cysteine proteinase, putative 0.0121 0.0586 0.1146
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0215 0.0201
Echinococcus multilocularis cpg binding protein 0.0029 0.0069 0.0055
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0088 0.0402 0.1412
Giardia lamblia Cathepsin L precursor 0.0053 0.02 0.1868
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0028 0.0059 0.0063
Brugia malayi glutathione reductase 0.0124 0.06 0.0606
Brugia malayi G-protein alpha subunit 0.0021 0.002 0.0007
Echinococcus granulosus cathepsin L 0.0053 0.02 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0516 0.2814 0.2804
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0043 0.0145 0.0524
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0053 0.02 0.1436
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0161 0.0148
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0053 0.02 0.0206
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0145 0.0262
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0021 0.002 0.0006
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0068 0.0054
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0196 0.1008 0.1992
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0437 0.0424
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0043 0.0145 0.3601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0161 0.1485
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0215 0.0201
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0074 0.006
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0143 0.0129
Trichomonas vaginalis D-aminoacylase, putative 0.0263 0.139 0.3369
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0028 0.006 0.0169
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0102 0.0237
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0053 0.02 0.1868
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0177 0.0163
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0302 0.0725
Giardia lamblia Cathepsin B precursor 0.0196 0.1008 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0043 0.0145 0.1315
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0506 0.2761 0.2751
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0074 0.0062
Trichomonas vaginalis ap endonuclease, putative 0.0174 0.0886 0.2144
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0798 0.0823
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0031 0.0081 0.0069
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0461 0.0448
Loa Loa (eye worm) hypothetical protein 0.014 0.0695 0.0717
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0307 0.0294
Loa Loa (eye worm) ctsf protein 0.0209 0.1081 0.1115
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0169 0.0401
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0028 0.006 0.0064
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0127 0.062 0.1215
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0028 0.006 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Trypanosoma cruzi mitochondrial protein 99, putative 0.0035 0.0102 0.0176
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0233 0.0226
Brugia malayi Cathepsin L-like precursor 0.0209 0.1081 0.1103
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.1379 0.3343
Schistosoma mansoni lamin 0.0058 0.0233 0.0219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0121 0.0586 0.1146
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0117 0.0564 0.0551
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0161 0.0148
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0206
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.002 0.0006
Plasmodium falciparum serine repeat antigen 2 0.0053 0.02 0.1845
Echinococcus multilocularis neuropeptide receptor A26 0.0462 0.2512 0.2501
Brugia malayi cathepsin L-like cysteine proteinase 0.0053 0.02 0.0192
Echinococcus multilocularis peptidase Clp (S14 family) 0.0058 0.023 0.0216
Entamoeba histolytica cysteine proteinase, putative 0.0121 0.0586 0.5357
Toxoplasma gondii hypothetical protein 0.003 0.0075 0.0222
Entamoeba histolytica hypothetical protein 0.0053 0.02 0.1739
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0043 0.0145 0.1337
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0035 0.0102 0.0939
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0099 0.0086
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0904 0.5004 1
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0028 0.006 0.0064
Schistosoma mansoni ap endonuclease 0.0174 0.0886 0.0873
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0102 0.0237
Brugia malayi Pre-SET motif family protein 0.0656 0.3606 0.371
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0127 0.062 0.1215
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0058
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0135 0.1135
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0028 0.0059 0.0198
Toxoplasma gondii LsmAD domain-containing protein 0.0081 0.0359 0.1255
Schistosoma mansoni cript-related 0.0035 0.0102 0.0088
Echinococcus multilocularis protein patched 0.0042 0.0143 0.0129
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.006 0.0047
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.002 0.0006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0174 0.0886 0.0914
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0145 0.1314
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Mycobacterium tuberculosis Probable lipase LipD 0.0263 0.139 0.1478
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0028 0.006 0.0169
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Schistosoma mansoni nuclear hormone receptor 0.003 0.0074 0.006
Plasmodium falciparum serine repeat antigen 4 0.0053 0.02 0.1845
Schistosoma mansoni chromobox protein 0.0071 0.0302 0.0289
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0033 0.0038
Entamoeba histolytica cysteine protease, putative 0.0053 0.02 0.1739
Plasmodium vivax unspecified product 0.0053 0.02 0.1436
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0062
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0028 0.006 0.0435
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0053 0.02 0.1436
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0028 0.006 0.0047
Echinococcus granulosus GPCR family 2 0.0117 0.0564 0.0551
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0028 0.006 0.0064
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0088 0.0402 0.289
Echinococcus granulosus intermediate filament protein 0.0058 0.0233 0.0219
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0231 0.0791
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0099 0.0086
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.002 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0068 0.049
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0021 0.002 0.0007
Brugia malayi Heterochromatin protein 1 0.0071 0.0302 0.0298
Leishmania major aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Schistosoma mansoni hypothetical protein 0.0253 0.133 0.1318
Entamoeba histolytica cysteine proteinase, putative 0.0209 0.1081 1
Entamoeba histolytica hypothetical protein 0.0025 0.0042 0.0267
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0028 0.006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0049 0.0177 0.0182
Schistosoma mansoni smad 0.0027 0.0054 0.004
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0021 0.002 0.0006
Schistosoma mansoni hypothetical protein 0.033 0.1766 0.1754
Entamoeba histolytica hypothetical protein 0.0035 0.0099 0.08
Loa Loa (eye worm) hypothetical protein 0.0033 0.009 0.0093
Onchocerca volvulus 0.0053 0.02 0.0438
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0028 0.006 0.0219
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0099 0.0086
Echinococcus multilocularis cathepsin b 0.0516 0.2814 0.2804
Loa Loa (eye worm) hypothetical protein 0.0058 0.0231 0.0238
Giardia lamblia PHD finger protein 15 0.0029 0.0068 0.0546
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 0.3714
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0798 0.081
Loa Loa (eye worm) hypothetical protein 0.0263 0.139 0.1433
Plasmodium falciparum serine repeat antigen 3 0.0053 0.02 0.1845
Onchocerca volvulus 0.0209 0.1081 0.2591
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0021
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0313 0.1671 0.1777
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.0307 0.0317
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0428 0.2317 0.4616
Brugia malayi MH2 domain containing protein 0.006 0.0241 0.0235
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0483 0.263 0.2619
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.02 0.0192
Onchocerca volvulus Cathepsin L homolog 0.0053 0.02 0.0438
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0135 0.0441
Brugia malayi MH1 domain containing protein 0.006 0.0241 0.0235
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Plasmodium falciparum importin beta, putative 0.0058 0.0231 0.2137
Brugia malayi Aldehyde dehydrogenase protein 4 0.0028 0.006 0.0048
Trichomonas vaginalis penicillin-binding protein, putative 0.0263 0.139 0.3369
Echinococcus multilocularis cathepsin b 0.0516 0.2814 0.2804
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0074 0.006
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0307 0.0294
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0074 0.0062
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0053 0.02 0.1436
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0042 0.0305
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.002 0.0007
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0035 0.0102 0.0105
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0169 0.0401
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Loa Loa (eye worm) RecQ helicase 0.002 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0041 0.0134 0.012
Leishmania major endonuclease/exonuclease protein-like protein 0.0035 0.0102 0.0176
Schistosoma mansoni cathepsin F (C01 family) 0.014 0.0695 0.0682
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.006 0.0093
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.002 0.0039
Brugia malayi beta-lactamase 0.0263 0.139 0.1421
Echinococcus multilocularis survival motor neuron protein 1 0.1018 0.5646 0.564
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0279 0.0287
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Schistosoma mansoni intermediate filament proteins 0.0058 0.0233 0.0219
Onchocerca volvulus Cathepsin F homolog 0.0209 0.1081 0.2591
Trypanosoma brucei glucosidase, putative 0.0035 0.0102 0.0176
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.02 0.0186
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0068 0.0054
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0043 0.0145 0.0262
Loa Loa (eye worm) Smad1 0.006 0.0241 0.0249
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0231 0.0435
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0043 0.0145 0.0262
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0483 0.263 0.2619
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0226 0.118 0.1168
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0209 0.1081 0.262
Leishmania major hypothetical protein, conserved 0.0263 0.139 0.2757
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0035 0.0102 0.0237
Plasmodium falciparum serine repeat antigen 8 0.0053 0.02 0.1845
Schistosoma mansoni alpha glucosidase 0.0035 0.0102 0.0088
Loa Loa (eye worm) TAR-binding protein 0.0072 0.0307 0.0317
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0028 0.006 0.0062
Plasmodium falciparum glutathione reductase 0.0124 0.06 0.5549
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0053 0.02 0.1845
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0483 0.263 0.2619
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0028 0.0059 0.016
Entamoeba histolytica hypothetical protein 0.0035 0.0099 0.08
Loa Loa (eye worm) transcription factor SMAD2 0.0879 0.4865 0.5017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0034
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0209 0.1081 0.1069
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0145 0.0131
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0145 0.1336
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.1379 0.3343
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0161 0.0383
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0033 0.0119
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0233 0.024
Brugia malayi Calcitonin receptor-like protein seb-1 0.037 0.1991 0.2042
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0043 0.0145 0.1041
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0053 0.02 0.0475
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0074 0.006
Loa Loa (eye worm) hypothetical protein 0.0209 0.1081 0.1115
Schistosoma mansoni ferritin 0.0028 0.0059 0.0045
Loa Loa (eye worm) pigment dispersing factor receptor c 0.037 0.1991 0.2053
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0112 0.0098
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0028 0.006 0.0098
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0177 0.0382
Loa Loa (eye worm) hypothetical protein 0.0081 0.0359 0.037
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0075 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0106 0.0502 0.0489
Leishmania major RNA-editing complex protein MP100, putative 0.0035 0.0102 0.0176
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0161 0.0148
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0021 0.002 0.0039
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0143 0.0129
Echinococcus multilocularis peregrin 0.0029 0.0068 0.0054
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0033 0.0177
Mycobacterium ulcerans aldehyde dehydrogenase 0.0506 0.2761 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0263 0.139 0.1478
Leishmania major mitochondrial DNA polymerase beta 0.0904 0.5004 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0279 0.0265
Mycobacterium leprae conserved hypothetical protein 0.0263 0.139 0.8285
Leishmania major aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0174 0.0886 0.1748
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 0.4259
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0144 0.034
Echinococcus granulosus mothers against decapentaplegic 5 0.006 0.0241 0.0228
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0035 0.0102 0.0939
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0074 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0033 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0879 0.4865 0.5017
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0021 0.002 0.0021
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0145 0.0476
Echinococcus multilocularis cathepsin L 0.0121 0.0586 0.0573
Mycobacterium ulcerans hypothetical protein 0.0263 0.139 0.5033
Leishmania major pantothenate kinase subunit, putative 0.0036 0.0107 0.0186
Loa Loa (eye worm) hypothetical protein 0.0052 0.0197 0.0203
Echinococcus multilocularis protein dispatched 1 0.0048 0.0177 0.0163
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0028 0.006 0.0219
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0028 0.006 0.0093
Plasmodium falciparum serine repeat antigen 6 0.0053 0.02 0.1845
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0231 0.0435
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1735 0.9696 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0021
Onchocerca volvulus 0.0092 0.0421 0.0977
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0033 0.0119
Onchocerca volvulus 0.0747 0.4117 1
Plasmodium vivax ataxin-2 like protein, putative 0.0081 0.0359 0.2581
Echinococcus granulosus cathepsin b 0.0516 0.2814 0.2804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.02 0.0475
Treponema pallidum exodeoxyribonuclease (exoA) 0.0174 0.0886 1
Brugia malayi Papain family cysteine protease containing protein 0.0209 0.1081 0.1103
Loa Loa (eye worm) beta-lactamase 0.0263 0.139 0.1433
Schistosoma mansoni apoferritin-2 0.0028 0.0059 0.0045
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0028 0.006 0.0219
Trypanosoma cruzi mitochondrial protein 99, putative 0.0035 0.0102 0.0176
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0028 0.006 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.02 0.0206
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0028 0.006 0.0047
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Mycobacterium tuberculosis Probable dehydrogenase 0.0282 0.1493 0.1588
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0043 0.0145 0.0524
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Entamoeba histolytica cysteine protease, putative 0.0053 0.02 0.1739
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.0695 0.1681
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0043 0.0145 0.0476
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0033 0.0177
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0398 0.0385
Schistosoma mansoni cpg binding protein 0.0029 0.0069 0.0055
Schistosoma mansoni ferritin 0.0028 0.0059 0.0045
Leishmania major cysteine peptidase A (CPA) 0.0209 0.1081 0.2139
Brugia malayi Cathepsin L-like precursor 0.0209 0.1081 0.1103
Mycobacterium tuberculosis Conserved hypothetical protein 0.0476 0.259 0.2755
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0036 0.0107 0.0186
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0127 0.062 0.1215
Loa Loa (eye worm) hypothetical protein 0.014 0.0695 0.0717
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0053 0.02 0.1868
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0278 0.1474 0.1462
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0053 0.02 0.0475
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0135 0.0121
Brugia malayi MH1 domain containing protein 0.0033 0.009 0.0079
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0028 0.006 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0035 0.0102 0.0176
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0028 0.006 0.0047
Echinococcus multilocularis beta LACTamase domain containing family member 0.0263 0.139 0.1378
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0486 0.0473
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0177 0.0163
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0035 0.0102 0.0088
Mycobacterium ulcerans esterase/lipase LipP 0.0263 0.139 0.5033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0821
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0035 0.0102 0.0176
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0053 0.02 0.1845
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Brugia malayi cathepsin B-like cysteine proteinase 0.0516 0.2814 0.2892
Echinococcus granulosus FTZ F1 alpha 0.003 0.0074 0.006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0117 0.0564 0.0581
Brugia malayi mbt repeat family protein 0.0049 0.0177 0.0168
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0021 0.002 0.0006
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0028 0.006 0.0093
Onchocerca volvulus Putative neutral sphingomyelinase 0.0035 0.0102 0.0198
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0062 0.0048
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0398 0.0385
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0042 0.0104
Brugia malayi hypothetical protein 0.0152 0.0759 0.0769
Schistosoma mansoni carbon catabolite repressor protein 0.0035 0.0102 0.0088
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0035 0.0102 0.0176
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0483 0.263 0.2619
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0028 0.006 0.0093
Loa Loa (eye worm) hypothetical protein 0.0263 0.139 0.1433
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Echinococcus granulosus cathepsin L cysteine proteinase 0.0209 0.1081 0.1069
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.002 0.0006
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0177 0.0163
Brugia malayi ecdysteroid receptor 0.003 0.0074 0.0062
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0028 0.006 0.0064
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0074 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0121 0.0586 0.1146
Plasmodium vivax vivapain-1 0.0121 0.0586 0.4215
Brugia malayi Smad1 0.006 0.0241 0.0235
Schistosoma mansoni thyroid hormone receptor 0.003 0.0074 0.006
Echinococcus multilocularis ferritin 0.0028 0.0059 0.0045
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0043 0.0145 0.1212
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Giardia lamblia Cysteine protease 0.0053 0.02 0.1868
Giardia lamblia Cysteine protease 0.0053 0.02 0.1868
Brugia malayi follicle stimulating hormone receptor 0.1735 0.9696 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0028 0.006 0.0219
Onchocerca volvulus 0.0028 0.006 0.0098
Brugia malayi MH2 domain containing protein 0.0027 0.0054 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Echinococcus multilocularis TGF beta signal transducer SmadC 0.006 0.0241 0.0228
Schistosoma mansoni alpha-glucosidase 0.0136 0.0673 0.066
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0028 0.006 0.0047
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.002 0.0006
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0068 0.0198
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Schistosoma mansoni hypothetical protein 0.0117 0.0564 0.0551
Entamoeba histolytica cysteine protease, putative 0.0053 0.02 0.1739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0074 0.0076
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0021 0.002 0.0039
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0102 0.0319
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0028 0.006 0.0047
Giardia lamblia Cathepsin L precursor 0.0053 0.02 0.1868
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0053 0.02 0.0475
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.014 0.0695 0.1365
Brugia malayi CHE-14 protein 0.0042 0.0143 0.0133
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0074 0.006
Trichomonas vaginalis ap endonuclease, putative 0.0174 0.0886 0.2144
Schistosoma mansoni chromobox protein 0.0071 0.0302 0.0289
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0701 0.0688
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0112 0.0115
Echinococcus multilocularis lamin 0.0058 0.0233 0.0219
Leishmania major GTP-binding protein, putative 0.0043 0.0145 0.0262
Brugia malayi Probable ClpP-like protease 0.0088 0.0402 0.0401
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0279 0.0531
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0088 0.0402 0.0388
Loa Loa (eye worm) hypothetical protein 0.0057 0.0227 0.0234
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0135 0.0121
Trichomonas vaginalis esterase, putative 0.0263 0.139 0.3369
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0043 0.0145 0.0262
Trichomonas vaginalis ferritin, putative 0.0028 0.0059 0.0134
Echinococcus multilocularis traf and tnf receptor associated protein 0.0035 0.0102 0.0088
Giardia lamblia hypothetical protein 0.0035 0.0102 0.0882
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0121 0.0586 0.0573
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0074 0.0062
Brugia malayi CXXC zinc finger family protein 0.0028 0.006 0.0048
Brugia malayi Cathepsin L-like precursor 0.0068 0.0289 0.0284
Plasmodium vivax vivapain-2 0.0209 0.1081 0.7782
Giardia lamblia Cysteine protease 0.0053 0.02 0.1868
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0043 0.0145 0.0262
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0821
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0209 0.1081 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0075 0.0385
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0068 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0074 0.0062
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0074 0.006
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0025 0.0011
Brugia malayi cathepsin F-like cysteine proteinase 0.0053 0.02 0.0192
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0506 0.2761 0.2751
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0021 0.002 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0074 0.0062
Schistosoma mansoni hypothetical protein 0.062 0.3405 0.3396
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0028 0.006 0.0435
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0028 0.006 0.0093
Plasmodium falciparum cysteine proteinase falcipain 3 0.0209 0.1081 1
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0174 0.0886 0.8193
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0033 0.0119
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 0.1455
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.1379 0.3343
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0161 0.0383
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0924 0.2236
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.002 0.0006
Schistosoma mansoni hypothetical protein 0.0208 0.1074 0.1062
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0033 0.0119
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0461 0.0462
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Brugia malayi hypothetical protein 0.0052 0.0197 0.0189
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0035 0.0102 0.0176
Giardia lamblia Cathepsin B precursor 0.0053 0.02 0.1868
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.002 0.0007
Plasmodium vivax thioredoxin reductase, putative 0.0124 0.06 0.4318
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0053 0.02 0.1436
Echinococcus granulosus traf and tnf receptor associated protein 0.0035 0.0102 0.0088
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.006 0.0047
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Schistosoma mansoni hypothetical protein 0.1789 1 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0821
Loa Loa (eye worm) cysteine protease 0.0209 0.1081 0.1115
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0135 0.0243
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0035 0.0102 0.0821
Echinococcus multilocularis snurportin 1 0.062 0.3405 0.3396
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Echinococcus granulosus mothers against decapentaplegic 6 0.0027 0.0054 0.004
Schistosoma mansoni smad1 5 8 and 0.006 0.0241 0.0228
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0053 0.02 0.1436
Brugia malayi mbt repeat family protein 0.0049 0.0177 0.0168
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Giardia lamblia Encystation-specific protease 0.0053 0.02 0.1868
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.1379 0.1422
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0028 0.006 0.0213
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0206
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.2141 0.213
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.139 0.2757
Toxoplasma gondii aldehyde dehydrogenase 0.0506 0.2761 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0068 0.0198
Echinococcus granulosus neuropeptide receptor A26 0.0462 0.2512 0.2501
Leishmania major importin beta-1 subunit, putative 0.0047 0.0169 0.0311
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0074 0.006
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0033 0.0038
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0035 0.0102 0.0176
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0174 0.0886 0.0942
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0121 0.0586 0.0573
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0152 0.0759 0.0782
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0428 0.2317 0.4616
Toxoplasma gondii NADPH-glutathione reductase 0.0043 0.0145 0.0476
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0231 0.0218
Echinococcus granulosus cathepsin L cysteine protease 0.0121 0.0586 0.0573
Brugia malayi exodeoxyribonuclease III family protein 0.0174 0.0886 0.0901
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0102 0.0237
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0174 0.0886 0.8169
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0028 0.006 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0143 0.0337
Loa Loa (eye worm) hypothetical protein 0.0103 0.0486 0.0501
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0053 0.02 0.1845
Schistosoma mansoni synaptojanin 0.0035 0.0102 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0263 0.139 1
Onchocerca volvulus 0.0035 0.0102 0.0198
Brugia malayi jmjC domain containing protein 0.0037 0.0112 0.0101
Echinococcus multilocularis chromobox protein 1 0.0071 0.0302 0.0289
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0904 0.5004 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0516 0.2814 0.2804
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0437 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Mycobacterium ulcerans lipase LipD 0.0263 0.139 0.5033
Mycobacterium tuberculosis Conserved protein 0.0263 0.139 0.1478
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0177 0.0163
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0174 0.0886 0.1748
Echinococcus multilocularis synaptojanin 1 0.0035 0.0102 0.0088
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0177 0.0163
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0102 0.0237
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0209 0.1081 0.1115
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0263 0.139 0.1478
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0053 0.02 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0105
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0053 0.02 0.1868
Echinococcus granulosus survival motor neuron protein 1 0.1018 0.5646 0.564
Brugia malayi Pre-SET motif family protein 0.0095 0.0437 0.0437
Treponema pallidum bacterioferrin (TpF1) 0.0028 0.0059 0.0198
Loa Loa (eye worm) fibroinase 0.0209 0.1081 0.1115
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0121 0.0586 0.1146
Onchocerca volvulus 0.0209 0.1081 0.2591
Schistosoma mansoni inositol monophosphatase 0.0041 0.0135 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.02 0.0475
Brugia malayi hypothetical protein 0.0035 0.0099 0.0088
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0033 0.0119
Brugia malayi Thioredoxin reductase 0.0124 0.06 0.0606
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0053 0.02 0.1739
Loa Loa (eye worm) MBCTL1 0.0055 0.0215 0.0221
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 0.1455
Giardia lamblia Hypothetical protein 0.0053 0.02 0.1868
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0531 0.2901 0.2982
Onchocerca volvulus 0.0058 0.0233 0.0519
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0437 0.0424
Entamoeba histolytica cysteine proteinase 2 0.0121 0.0586 0.5357
Brugia malayi RNA, U transporter 1 0.0165 0.0836 0.0849
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0313 0.1671 1
Schistosoma mansoni cathepsin C 0.0053 0.02 0.0186
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0279 0.0265
Echinococcus multilocularis neuropeptide s receptor 0.0462 0.2512 0.2501
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0028 0.006 0.0047
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0161 0.0296
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0028 0.006 0.0168
Schistosoma mansoni hypothetical protein 0.0029 0.0068 0.0054
Onchocerca volvulus 0.0209 0.1081 0.2591
Brugia malayi nuclear receptor NHR-88 0.003 0.0074 0.0062
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0035 0.0102 0.0176
Trypanosoma cruzi cruzipain precursor, putative 0.0209 0.1081 0.2139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0586 0.1415
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0074 0.006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0033 0.0119
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0798 0.0785
Echinococcus granulosus smad 0.006 0.0241 0.0228
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Loa Loa (eye worm) cathepsin B 0.0196 0.1008 0.104
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0233 0.024
Echinococcus granulosus neutral sphingomyelinase 0.0035 0.0102 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0307 0.0294
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0102 0.0088
Echinococcus granulosus peregrin 0.0029 0.0068 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0244 0.0252
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.002 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0043 0.0145 0.0262
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0516 0.2814 0.2804
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0135 0.0318
Echinococcus multilocularis mothers against decapentaplegic 2 0.0027 0.0054 0.004
Echinococcus multilocularis chromobox protein 1 0.0071 0.0302 0.0289
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Onchocerca volvulus 0.0209 0.1081 0.2591
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0871 0.2078
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0034
Brugia malayi aldehyde dehydrogenase 0.0028 0.006 0.0048
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0102 0.0237
Schistosoma mansoni cathepsin s 0.0068 0.0289 0.0276
Trichomonas vaginalis D-aminoacylase, putative 0.0263 0.139 0.3369
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0021
Echinococcus multilocularis musashi 0.0058 0.0233 0.0219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0028 0.006 0.0219
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0042 0.0104
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 0.4259
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0161 0.0148
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0111 0.0118
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0135 0.1098
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0043 0.0145 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0127 0.0299
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0112 0.0098
Echinococcus multilocularis geminin 0.1789 1 1
Echinococcus multilocularis GPCR, family 2 0.0117 0.0564 0.0551
Toxoplasma gondii ABC1 family protein 0.0263 0.139 0.5008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0074 0.0062
Schistosoma mansoni hypothetical protein 0.0041 0.0134 0.012
Loa Loa (eye worm) aldehyde dehydrogenase 0.0028 0.006 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0074 0.0062
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0028 0.006 0.0047
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0701 0.0688
Giardia lamblia Alcohol dehydrogenase 0.0028 0.006 0.0468
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0359 0.0691
Giardia lamblia Hypothetical protein 0.0053 0.02 0.1868
Brugia malayi steroid hormone receptor 0.003 0.0074 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.02 0.0475
Schistosoma mansoni hypothetical protein 0.0041 0.0134 0.012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0074 0.006
Echinococcus multilocularis cathepsin L cysteine protease 0.0209 0.1081 0.1069
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0053 0.02 0.1739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0074 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.1379 0.3343
Echinococcus granulosus cathepsin l cysteine peptidase 0.0209 0.1081 0.1069
Loa Loa (eye worm) G protein alpha subunit 3 0.0021 0.002 0.0021
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0279 0.0265
Plasmodium vivax unspecified product 0.0068 0.0289 0.2082
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0053 0.02 0.0475
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0103 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Plasmodium vivax serine-repeat antigen (SERA) 0.0053 0.02 0.1436
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0161 0.1383
Toxoplasma gondii cathepsin CPC2 0.0053 0.02 0.0676
Toxoplasma gondii cathepsin CPL 0.0209 0.1081 0.3886
Treponema pallidum NADH oxidase 0.0043 0.0145 0.1212
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0289 0.0552
Entamoeba histolytica Ran family GTPase 0.0043 0.0145 0.1224
Mycobacterium tuberculosis Conserved protein 0.0263 0.139 0.1478
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0124 0.06 0.0638
Schistosoma mansoni importin beta-1 0.0058 0.0231 0.0218
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0279 0.0531
Schistosoma mansoni aldehyde dehydrogenase 0.0506 0.2761 0.2751
Loa Loa (eye worm) hypothetical protein 0.0263 0.139 0.1433
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.02 0.0475
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0215 0.0201
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.139 0.2757
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0043 0.0145 0.0135
Schistosoma mansoni apoferritin-2 0.0028 0.0059 0.0045
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0586 0.0591
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0043 0.0145 0.0131
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0302 0.0312
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0088 0.0402 0.1412
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0359 0.3317
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0279 0.0531
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0289 0.0552
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0102 0.0176
Echinococcus multilocularis cathepsin L 0.0053 0.02 0.0186
Entamoeba histolytica cysteine proteinase, putative 0.014 0.0695 0.6382
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.02 0.0372
Toxoplasma gondii thioredoxin reductase 0.0124 0.06 0.2134
Brugia malayi cathepsin L precursor 0.0053 0.02 0.0192
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0302 0.0725
Echinococcus granulosus importin subunit beta 1 0.0058 0.0231 0.0218
Schistosoma mansoni ran 0.0043 0.0145 0.0131
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0035 0.0102 0.0821
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0035 0.0102 0.0939
Plasmodium vivax unspecified product 0.0121 0.0586 0.4215
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0206
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0035 0.0102 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.0209 0.1081 0.2139
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0209 0.1081 0.1069
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0827 0.4573 0.4566
Echinococcus multilocularis lamin dm0 0.0058 0.0233 0.0219
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0021 0.002 0.0007
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.008 0.0082
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0014 0.0024
Brugia malayi cathepsin Z-like cysteine proteinase 0.0053 0.02 0.0192
Entamoeba histolytica cysteine protease, putative 0.0209 0.1081 1
Giardia lamblia Cathepsin B precursor 0.0053 0.02 0.1868
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.022 0.0751
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0053 0.02 0.1436
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0053 0.02 0.0186
Schistosoma mansoni Smad4 0.0027 0.0054 0.004
Schistosoma mansoni lamin 0.0058 0.0233 0.0219
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0035 0.0102 0.0176
Brugia malayi hypothetical protein 0.0021 0.002 0.0007
Brugia malayi CCR4 0.0035 0.0102 0.0091
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0135 0.0243
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.006 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0398 0.0385
Schistosoma mansoni thyroid hormone receptor 0.003 0.0074 0.006
Echinococcus granulosus Smad4 0.006 0.0241 0.0228
Schistosoma mansoni Smad4 0.006 0.0241 0.0228
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0169 0.0311
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0035 0.0102 0.0088
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0174 0.0886 1
Echinococcus granulosus cathepsin l1 0.014 0.0695 0.0682
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.002 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0924 0.2236
Brugia malayi RNA binding protein 0.0072 0.0307 0.0303
Entamoeba histolytica cysteine proteinase, putative 0.0121 0.0586 0.5357
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0028 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0105
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0074 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.02 0.0475
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0145 0.0131
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0028 0.006 0.0047
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0161 0.0148
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0014 0.0014
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0102 0.0176
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0102 0.0105
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0102 0.0091
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0821
Giardia lamblia Cathepsin L-like protease 0.0053 0.02 0.1868
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0112 0.0098
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0054 0.0056
Echinococcus multilocularis tar DNA binding protein 0.0072 0.0307 0.0294
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0161 0.0296
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0021 0.002 0.0007
Mycobacterium ulcerans bacterioferritin BfrA 0.0028 0.0059 0.0214
Mycobacterium tuberculosis Probable hydrolase 0.0263 0.139 0.1478
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0307 0.0294
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0145 0.0262
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0074 0.006
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0014 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.1379 0.3343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Leishmania major hypothetical protein, conserved 0.0035 0.0102 0.0176
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0035 0.0102 0.0088
Echinococcus granulosus peptidase Clp S14 family 0.0058 0.023 0.0216
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0209 0.1081 1
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0021 0.002 0.0007
Trichomonas vaginalis Phospholipase C precursor, putative 0.0035 0.0102 0.0237
Schistosoma mansoni peptidase Clp (S14 family) 0.0088 0.0402 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0174 0.0886 0.1748
Loa Loa (eye worm) hypothetical protein 0.0068 0.0289 0.0298
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0437 0.1541
Entamoeba histolytica cysteine proteinase, putative 0.0121 0.0586 0.5357
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0028 0.006 0.0219
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0135 0.0318
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0034
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0437 0.0424
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0021 0.002 0.0006
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0821
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Loa Loa (eye worm) thioredoxin reductase 0.0124 0.06 0.0619
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.002 0.0006
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0035 0.0102 0.0176
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0506 0.2761 0.2937
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.02 0.0372
Trichomonas vaginalis D-aminoacylase, putative 0.0263 0.139 0.3369
Onchocerca volvulus 0.0088 0.0398 0.0923
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0278 0.1474 0.1462
Schistosoma mansoni survival motor neuron protein 0.0208 0.1074 0.1062
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0263 0.139 0.5033
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0028 0.006 0.0169
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0586 0.0591
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0135 0.0318
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0144 0.0302
Brugia malayi MH1 domain containing protein 0.006 0.0241 0.0235
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0033 0.0119
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0074 0.0076
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.002 0.0006
Brugia malayi Bromodomain containing protein 0.0029 0.0068 0.0056
Schistosoma mansoni hypothetical protein 0.0117 0.0564 0.0551
Brugia malayi cathepsin F-like cysteine proteinase 0.0068 0.0289 0.0284
Brugia malayi latrophilin 2 splice variant baaae 0.0253 0.133 0.136
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0437 0.0424
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0131
Schistosoma mansoni hypothetical protein 0.0041 0.0134 0.012
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0035 0.0102 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0053 0.02 0.0475
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0074 0.0076
Brugia malayi Cathepsin L-like precursor 0.0209 0.1081 0.1103
Mycobacterium tuberculosis Probable exported protein 0.0035 0.0102 0.0108
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0117 0.0564 0.0551
Brugia malayi Inositol-1 0.0041 0.0135 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0102 0.0176
Schistosoma mansoni ferritin 0.0028 0.0059 0.0045
Mycobacterium tuberculosis Probable reductase 0.0282 0.1493 0.1588
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.002 0.0039
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.02 0.0192
Mycobacterium tuberculosis Probable oxidoreductase 0.0313 0.1671 0.1777
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0021 0.002 0.0039
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0282 0.1493 0.1588
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0483 0.263 0.2619
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Schistosoma mansoni cpg binding protein 0.0028 0.006 0.0046
Entamoeba histolytica G protein alpha subunit, putative 0.0021 0.002 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.014 0.0695 0.1681
Echinococcus granulosus expressed conserved protein 0.0093 0.0428 0.0414
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0319
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0074 0.006
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.02 0.0186
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0033 0.0035
Treponema pallidum hypothetical protein 0.0035 0.0102 0.0701
Loa Loa (eye worm) hypothetical protein 0.0031 0.0078 0.0081
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0074 0.006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0161 0.0383
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0035 0.0102 0.0237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0174 0.0886 0.8772
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0028 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0035 0.0102 0.0105
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0263 0.139 0.1478
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0053 0.02 0.1436
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0483 0.263 0.2619
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0074 0.0076
Brugia malayi intermediate filament protein 0.0058 0.0233 0.0226
Giardia lamblia Inositol 5-phosphatase 4 0.0035 0.0102 0.0882
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0075 0.0692
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.02 0.0475
Echinococcus granulosus mothers against decapentaplegic 2 0.0027 0.0054 0.004
Trypanosoma brucei cysteine peptidase C (CPC) 0.0196 0.1008 0.1992
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0307 0.0294
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0074 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0074 0.0076
Brugia malayi Cathepsin L-like precursor 0.0209 0.1081 0.1103
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0035 0.0102 0.0237
Loa Loa (eye worm) hypothetical protein 0.0531 0.2901 0.2992
Leishmania major hypothetical protein, conserved 0.0035 0.0102 0.0176
Brugia malayi Cathepsin L-like cysteine proteinase 0.014 0.0695 0.0704
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.002 0.0006
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0133 0.0119
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0035 0.0102 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0145 0.104
Entamoeba histolytica cysteine proteinase, putative 0.0121 0.0586 0.5357
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.006 0.0093
Brugia malayi beta-lactamase family protein 0.0263 0.139 0.1421
Echinococcus multilocularis cathepsin L cysteine protease 0.0209 0.1081 0.1069
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0035 0.0102 0.073
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0028 0.006 0.0047
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0074 0.006
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0035 0.0102 0.0237
Schistosoma mansoni coup transcription factor 0.003 0.0074 0.006
Brugia malayi Cathepsin L-like precursor 0.0209 0.1081 0.1103
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Onchocerca volvulus 0.0103 0.0486 0.1137
Treponema pallidum gamma-glutamyl phosphate reductase 0.0028 0.006 0.0213
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0161 0.0148
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0028 0.006 0.0048
Schistosoma mansoni ferritin light chain 0.0028 0.0059 0.0045
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.008 0.0068
Loa Loa (eye worm) glutathione reductase 0.0124 0.06 0.0619
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0068 0.0289 0.0298
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0035 0.0102 0.0237
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.002 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Schistosoma mansoni Smad4 0.0027 0.0054 0.004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0074 0.0062
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0074 0.006
Onchocerca volvulus 0.0263 0.139 0.3343
Echinococcus granulosus lamin dm0 0.0058 0.0233 0.0219
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0215 0.0201
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.002 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0483 0.263 0.2712
Onchocerca volvulus 0.0208 0.1074 0.2574
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0021 0.002 0.0021
Echinococcus multilocularis tumor protein p63 0.0706 0.3886 0.3877
Loa Loa (eye worm) MH2 domain-containing protein 0.006 0.0241 0.0249
Echinococcus multilocularis cysteine protease 0.0209 0.1081 0.1069
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0053 0.02 0.1868
Trypanosoma cruzi cysteine peptidase, putative 0.0209 0.1081 0.2139
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.02 0.0186
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0035 0.0102 0.0105
Echinococcus granulosus cpg binding protein 0.0029 0.0069 0.0055
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0102 0.0237
Schistosoma mansoni ran 0.0043 0.0145 0.0131
Plasmodium falciparum serine repeat antigen 5 0.0053 0.02 0.1845
Loa Loa (eye worm) hypothetical protein 0.0055 0.0215 0.0221
Trypanosoma cruzi cysteine peptidase, putative 0.0121 0.0586 0.1146
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0035 0.0102 0.0821
Brugia malayi nuclear hormone receptor 0.003 0.0074 0.0062
Mycobacterium leprae Probable lipase LipE 0.0263 0.139 0.8285
Leishmania major hypothetical protein, conserved 0.0081 0.0359 0.0691
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0074 0.006
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0359 0.0691
Loa Loa (eye worm) nuclear factor I 0.0033 0.009 0.0093
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0102 0.0822
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0209 0.1081 0.262
Plasmodium vivax vivapain-2 0.0209 0.1081 0.7782
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0398 0.0397
Giardia lamblia Cathepsin L-like protease 0.0053 0.02 0.1868
Mycobacterium ulcerans bacterioferritin BfrB 0.0028 0.0059 0.0214
Brugia malayi Cathepsin L-like precursor 0.014 0.0695 0.0704
Onchocerca volvulus 0.0031 0.0078 0.0142
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Giardia lamblia Cysteine protease 0.0053 0.02 0.1868
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0215 0.0207
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0282 0.1493 0.1588
Brugia malayi mothers against decapentaplegic homolog 3 0.0027 0.0054 0.0042
Trichomonas vaginalis ran, putative 0.0043 0.0145 0.0342
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0042 0.1055
Onchocerca volvulus 0.0152 0.0759 0.1803
Onchocerca volvulus 0.0209 0.1081 0.2591
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0428 0.2317 0.4616
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0028 0.006 0.0093
Giardia lamblia Cathepsin L precursor 0.0053 0.02 0.1868
Echinococcus granulosus thioredoxin glutathione reductase 0.0125 0.0606 0.0593
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.006 0.0062
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.02 0.0186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0028 0.006 0.0435
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.02 0.0206
Onchocerca volvulus 0.0263 0.139 0.3343
Schistosoma mansoni smad1 5 8 and 0.006 0.0241 0.0228
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0033 0.0038
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0028 0.006 0.0064
Echinococcus multilocularis smad 0.006 0.0241 0.0228
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0145 0.0262
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0282 0.1493 0.1588
Giardia lamblia Cathepsin L precursor 0.0053 0.02 0.1868
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0076
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0062 0.0048
Loa Loa (eye worm) hypothetical protein 0.1018 0.5646 0.5823
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0088 0.0402 1
Loa Loa (eye worm) MH1 domain-containing protein 0.006 0.0241 0.0249
Plasmodium vivax SET domain protein, putative 0.0095 0.0437 0.3145
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0014 0.00000000018366
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0516 0.2814 0.2804
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0871 0.2109
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0035 0.0102 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0074 0.006
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0282 0.1493 0.1588
Echinococcus granulosus expressed protein 0.0021 0.002 0.0006
Mycobacterium tuberculosis Conserved protein 0.0263 0.139 0.1478
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0483 0.263 0.2619
Leishmania major cathepsin L-like protease 0.0209 0.1081 0.2139
Mycobacterium ulcerans aldehyde dehydrogenase 0.0506 0.2761 1
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0028 0.006 0.0219
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0042 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0035 0.0102 0.0939
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0035 0.0102 0.0176
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0028 0.006 0.0219
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0102 0.0091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0016 0.0002
Echinococcus multilocularis expressed protein 0.0021 0.002 0.0006
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Schistosoma mansoni TGF-beta signal transducer Smad2 0.006 0.0241 0.0228
Mycobacterium ulcerans hypothetical protein 0.0476 0.259 0.938
Onchocerca volvulus 0.014 0.0695 0.1648
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0107 0.0094
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0042 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0074 0.0062
Giardia lamblia Cathepsin B precursor 0.0196 0.1008 1
Onchocerca volvulus 0.0263 0.139 0.3343
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.006 0.0093
Schistosoma mansoni alpha-glucosidase 0.0136 0.0673 0.066
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0028 0.006 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.1081 0.262
Loa Loa (eye worm) hypothetical protein 0.0263 0.139 0.1433
Plasmodium falciparum glutathione reductase 0.0043 0.0145 0.1337
Brugia malayi MH2 domain containing protein 0.0879 0.4865 0.501
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0656 0.3606 0.3719
Trypanosoma brucei PAB1-binding protein , putative 0.0081 0.0359 0.0691
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0035 0.0102 0.0237
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.002 0.0006
Trichomonas vaginalis mercuric reductase, putative 0.0043 0.0145 0.0342
Loa Loa (eye worm) hypothetical protein 0.0088 0.0402 0.0414
Giardia lamblia Cathepsin B precursor 0.0196 0.1008 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0174 0.0886 0.6375
Echinococcus granulosus cathepsin b 0.0516 0.2814 0.2804
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0215 0.0201
Echinococcus granulosus chromobox protein 1 0.0071 0.0302 0.0289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0145 0.0149
Plasmodium vivax importin-beta 2, putative 0.0058 0.0231 0.1663
Brugia malayi TAR-binding protein 0.0072 0.0307 0.0303
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0014 0.0024
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.002 0.0006
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0021 0.002 0.0007
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0279 0.248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0209 0.1081 0.2139
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0042 0.0058
Entamoeba histolytica hypothetical protein 0.0035 0.0099 0.08
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0127 0.026
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0102 0.0088
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.006 0.0047
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0107 0.0094
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0144 0.034
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0169 0.0401
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.062 0.3405 0.3512
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0074 0.0062
Loa Loa (eye worm) RNA binding protein 0.0072 0.0307 0.0317
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0074 0.0062
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0444 0.043
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.002 0.0006
Onchocerca volvulus Cathepsin L homolog 0.0209 0.1081 0.2591
Plasmodium vivax exodeoxyribonuclease III, putative 0.0035 0.0102 0.073
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0516 0.2814 0.5611
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0143 0.0129
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0035 0.0102 0.0176
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0161 0.0148
Schistosoma mansoni hypothetical protein 0.0396 0.2141 0.213
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0074 0.006
Mycobacterium tuberculosis Probable lipase LipE 0.0263 0.139 0.1478
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0359 0.3317
Brugia malayi chromobox protein homolog 3 0.004 0.0127 0.0117
Giardia lamblia Cathepsin L precursor 0.0053 0.02 0.1868
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0444 0.043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0058
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0043 0.0145 0.0524
Echinococcus granulosus transcription factor Dp 1 0.0039 0.012 0.0107
Giardia lamblia Cathepsin B precursor 0.0053 0.02 0.1868
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0483 0.263 0.2702
Schistosoma mansoni cathepsin S (C01 family) 0.0053 0.02 0.0186
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0043 0.0145 0.0262
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0068 0.0289 0.0284
Entamoeba histolytica cysteine protease, putative 0.0053 0.02 0.1739
Entamoeba histolytica hypothetical protein 0.0035 0.0099 0.08
Echinococcus granulosus tar DNA binding protein 0.0072 0.0307 0.0294
Echinococcus granulosus expressed protein 0.0028 0.0059 0.0045
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0196 0.1008 0.1992
Echinococcus multilocularis Smad4 0.006 0.0241 0.0228
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0102 0.0237
Plasmodium vivax glutathione reductase, putative 0.0124 0.06 0.4318
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0263 0.139 0.1421
Loa Loa (eye worm) hypothetical protein 0.0099 0.0461 0.0476
Toxoplasma gondii cathepsin B 0.0196 0.1008 0.3619
Echinococcus multilocularis mothers against decapentaplegic 5 0.006 0.0241 0.0228
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0105
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0042 0.0153
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0035 0.0102 0.0821
Brugia malayi Importin beta-1 subunit 0.0058 0.0231 0.0224
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0074 0.006
Entamoeba histolytica cysteine proteinase, putative 0.0209 0.1081 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0074 0.0062
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0256 0.0242
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.012 0.0107
Echinococcus multilocularis thioredoxin glutathione reductase 0.0125 0.0606 0.0593
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0506 0.2761 0.5505
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.1379 0.141
Echinococcus multilocularis expressed conserved protein 0.0093 0.0428 0.0414
Echinococcus granulosus dnaJ subfamily B 0.0396 0.2141 0.213
Loa Loa (eye worm) hypothetical protein 0.0095 0.0437 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0117 0.0564 0.0568
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0263 0.139 0.1378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0075 0.0539
Trypanosoma cruzi cysteine peptidase, putative 0.0209 0.1081 0.2139
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.002 0.0006
Echinococcus multilocularis neutral sphingomyelinase 0.0035 0.0102 0.0088
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0074 0.006
Schistosoma mansoni hypothetical protein 0.0117 0.0564 0.0551
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0145 0.0262
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0313 0.1671 0.1777
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0028 0.0059 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0904 0.5004 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0043 0.0145 0.0131
Loa Loa (eye worm) hypothetical protein 0.0263 0.139 0.1433
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0074 0.006
Mycobacterium ulcerans hypothetical protein 0.0023 0.0033 0.0119
Echinococcus multilocularis expressed protein 0.0028 0.0059 0.0045
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0145 0.0262
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0102 0.0237
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0028 0.006 0.0064
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0035 0.0102 0.0105
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0053 0.02 0.1436
Schistosoma mansoni hypothetical protein 0.0117 0.0564 0.0551
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0161 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0053 0.02 0.0475
Onchocerca volvulus Alhambra homolog 0.0029 0.0068 0.0117
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0028 0.006 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0033 0.0035
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0035 0.0102 0.0088
Schistosoma mansoni patched 1 0.0042 0.0143 0.0129
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0043 0.0145 0.1337
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0058 0.023 0.1204
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0437 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.1081 0.262
Schistosoma mansoni synaptojanin 0.0035 0.0102 0.0088
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0282 0.1493 0.8917
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0035 0.0102 0.0176
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0014 0.0128
Brugia malayi jmjC domain containing protein 0.0096 0.0444 0.0444
Entamoeba histolytica cysteine protease, putative 0.0121 0.0586 0.5357
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0161 0.0296
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0206
Schistosoma mansoni cpg binding protein 0.0029 0.0069 0.0055
Trypanosoma brucei RNA editing exonuclease 2 0.0035 0.0102 0.0176
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0461 0.4192
Onchocerca volvulus 0.0106 0.0502 0.1177
Toxoplasma gondii hypothetical protein 0.0146 0.0726 0.2592

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 5.873 uM PubChem BioAssay. Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1). (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 7.103 uM PubChem BioAssay. Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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