Detailed information for compound 1337619

Basic information

Technical information
  • TDR Targets ID: 1337619
  • Name: methyl 3-[(3-nitrophenyl)carbamoylamino]thiop hene-2-carboxylate
  • MW: 321.309 | Formula: C13H11N3O5S
  • H donors: 2 H acceptors: 4 LogP: 2.73 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1sccc1NC(=O)Nc1cccc(c1)[N+](=O)[O-]
  • InChi: 1S/C13H11N3O5S/c1-21-12(17)11-10(5-6-22-11)15-13(18)14-8-3-2-4-9(7-8)16(19)20/h2-7H,1H3,(H2,14,15,18)
  • InChiKey: VRGPZIXENFWGJU-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 3-[[[(3-nitrophenyl)amino]-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester
  • 3-[(3-nitrophenyl)carbamoylamino]thiophene-2-carboxylic acid methyl ester
  • ZINC02857807
  • IVK/1201987

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0406 0.0325 0.0325
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0247 0.0099 0.0099
Onchocerca volvulus 0.0266 0.0125 0.0345
Trichomonas vaginalis CMGC family protein kinase 0.0395 0.031 0.1411
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0755 0.0824 0.1407
Schistosoma mansoni serine/threonine protein kinase 0.0573 0.0565 0.0565
Echinococcus multilocularis Rac GTPase activating protein 1 0.0189 0.0015 0.0026
Plasmodium falciparum calcium-dependent protein kinase 1 0.032 0.0202 0.1445
Echinococcus multilocularis epidermal growth factor receptor 0.3042 0.4091 0.6983
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0519 0.0488 0.0833
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0657 0.0684 0.3576
Loa Loa (eye worm) AGC/NDR protein kinase 0.0788 0.0871 0.0871
Giardia lamblia Kinase, NEK 0.0661 0.0691 0.3852
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0339 0.0229 0.0326
Onchocerca volvulus 0.0705 0.0753 0.207
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.1167
Schistosoma mansoni nephrin 0.0491 0.0447 0.0447
Echinococcus multilocularis serine:threonine protein kinase N2 0.0252 0.0105 0.0179
Loa Loa (eye worm) hypothetical protein 0.0251 0.0104 0.0104
Schistosoma mansoni serine/threonine kinase 0.0686 0.0726 0.0726
Giardia lamblia Kinase, CMGC GSK 0.0623 0.0636 0.3509
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0099 0.0292
Brugia malayi Protein kinase c protein 2 0.0534 0.0508 0.0508
Echinococcus multilocularis tyrosine protein kinase HCK 0.047 0.0417 0.0711
Echinococcus granulosus mitogen activated protein kinase 3 0.0395 0.031 0.0441
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0661 0.0691 0.3612
Brugia malayi Protein kinase domain containing protein 0.1237 0.1513 0.1513
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0573 0.0565 0.0565
Loa Loa (eye worm) hypothetical protein 0.0199 0.0031 0.0031
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0201 0.0034 0.0057
Schistosoma mansoni unc-13 (munc13) 0.0195 0.0024 0.0024
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.024 0.0089 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0089 0.0236
Plasmodium vivax serine/threonine kinase-1, putative 0.0371 0.0276 0.2452
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1032 0.122 0.1734
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Schistosoma mansoni titin 0.0244 0.0094 0.0094
Entamoeba histolytica protein kinase, putative 0.032 0.0202 0.0982
Schistosoma mansoni protein kinase 0.0678 0.0715 0.0715
Brugia malayi hypothetical protein 0.0406 0.0325 0.0325
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Echinococcus granulosus tyrosine protein kinase Blk 0.0619 0.0631 0.0896
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0371 0.0276 0.0276
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.0531 0.2579
Trichomonas vaginalis STE family protein kinase 0.0297 0.017 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0269 0.0131 0.0459
Echinococcus multilocularis protein kinase c iota type 0.1397 0.1742 0.2973
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0384 0.0294 0.0294
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0199 0.0031 0.0053
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0755 0.0824 0.1407
Echinococcus granulosus cyclin dependent kinase 1 0.0573 0.0565 0.0802
Loa Loa (eye worm) hypothetical protein 0.0894 0.1022 0.1022
Brugia malayi Protein kinase domain 0.0407 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0705 0.0753 0.0753
Entamoeba histolytica protein kinase, putative 0.0623 0.0636 0.3247
Leishmania major casein kinase II, putative 0.0678 0.0715 0.4005
Entamoeba histolytica protein kinase, putative 0.0788 0.0871 0.447
Echinococcus multilocularis serine:threonine protein kinase 0.0549 0.0531 0.0906
Brugia malayi MAP kinase sur-1 0.0395 0.031 0.031
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0247 0.0099 0.0099
Echinococcus granulosus roundabout 2 0.0584 0.058 0.0823
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0623 0.0636 0.0904
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0709 0.0758 0.3883
Echinococcus multilocularis serine:threonine protein kinase N2 0.0788 0.0871 0.1487
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Schistosoma mansoni ephrin receptor 0.0193 0.0022 0.0022
Giardia lamblia Kinase, CMGC DYRK 0.024 0.0089 0.005
Brugia malayi Variant SH3 domain containing protein 0.0286 0.0154 0.0154
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0807 0.0899 0.0899
Echinococcus granulosus insulin receptor 0.2216 0.2911 0.4135
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1343 0.1664 0.2363
Onchocerca volvulus 0.1621 0.2062 0.5669
Echinococcus multilocularis ephrin type A receptor 4 A 0.0497 0.0456 0.0778
Echinococcus multilocularis dual specificity 0.024 0.0089 0.0152
Brugia malayi SH2 domain containing protein 0.0322 0.0205 0.0205
Echinococcus granulosus fibroblast growth factor receptor 4 0.1179 0.143 0.2031
Trypanosoma brucei Casein kinase II 0.0678 0.0715 0.3427
Entamoeba histolytica protein kinase, putative 0.0384 0.0294 0.146
Echinococcus multilocularis protein kinase shaggy 0.0623 0.0636 0.1086
Echinococcus granulosus protein kinase C gamma type 0.0995 0.1168 0.1659
Brugia malayi Protein kinase domain containing protein 0.0549 0.0531 0.0531
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.2237 0.2942 0.5022
Echinococcus multilocularis protein kinase c epsilon type 0.0983 0.1149 0.1962
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0709 0.0758 0.7805
Entamoeba histolytica protein kinase , putative 0.0709 0.0758 0.3883
Trypanosoma cruzi polo-like protein kinase, putative 0.1343 0.1664 1
Schistosoma mansoni serine/threonine protein kinase 0.1215 0.1481 0.1481
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.0466 0.0466
Echinococcus multilocularis casein kinase I alpha 0.0403 0.0321 0.0549
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1179 0.143 0.244
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.032 0.0202 0.0202
Trypanosoma cruzi aurora B kinase, putative 0.0709 0.0758 0.428
Trichomonas vaginalis CMGC family protein kinase 0.0573 0.0565 0.2759
Echinococcus granulosus aurora kinase A 0.0709 0.0758 0.1077
Plasmodium falciparum protein kinase, putative 0.0309 0.0187 0.1272
Plasmodium falciparum calcium-dependent protein kinase 5 0.032 0.0202 0.1445
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.1167
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0287
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0309 0.0187 0.0575
Echinococcus multilocularis mitogen activated protein kinase 14 0.0778 0.0857 0.1463
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0322 0.0205 0.0292
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0251 0.0104 0.0148
Plasmodium vivax tyrosine kinase-like protein, putative 0.023 0.0075 0.0218
Echinococcus multilocularis cyclin dependent kinase 1 0.0573 0.0565 0.0964
Echinococcus granulosus tyrosine protein kinase Fyn 0.0755 0.0824 0.1171
Schistosoma mansoni adapter molecule crk 0.0286 0.0154 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0939 0.1087 0.1856
Giardia lamblia Kinase, CDC7 0.0247 0.0099 0.0117
Loa Loa (eye worm) hypothetical protein 0.0533 0.0508 0.0508
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0388 0.03 0.0512
Trypanosoma cruzi polo-like protein kinase, putative 0.1343 0.1664 1
Schistosoma mansoni serine/threonine protein kinase 0.1621 0.2062 0.2062
Loa Loa (eye worm) AGC/PKA protein kinase 0.0657 0.0684 0.0684
Echinococcus multilocularis tyrosine kinase 0.0322 0.0205 0.035
Loa Loa (eye worm) TK protein kinase 0.1264 0.1551 0.1551
Loa Loa (eye worm) hypothetical protein 0.018 0.0004 0.0004
Echinococcus granulosus serine:threonine protein kinase N2 0.1039 0.123 0.1747
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0778 0.0857 0.4905
Giardia lamblia Kinase, STE STE20 0.0407 0.0327 0.1554
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0778 0.0857 0.0857
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.0276 0.0276
Brugia malayi Sex muscle abnormal protein 5 0.0286 0.0154 0.0154
Schistosoma mansoni growth factor receptor-bound protein 0.0286 0.0154 0.0154
Onchocerca volvulus 0.2467 0.327 0.8992
Brugia malayi SRC-1 0.0755 0.0824 0.0824
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0859 0.0973 0.0973
Echinococcus multilocularis casein kinase I gamma 0.0254 0.0108 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0573 0.0565 0.0565
Entamoeba histolytica hypothetical protein 0.0189 0.0015 0.0006
Echinococcus granulosus serine:threonine protein kinase 3 0.1274 0.1566 0.2225
Loa Loa (eye worm) TK/ALK protein kinase 0.063 0.0646 0.0646
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0294 0.1324
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.032 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0318 0.02 0.02
Brugia malayi Protein kinase domain containing protein 0.0573 0.0565 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0823 0.0921 0.0921
Echinococcus multilocularis serine:threonine protein kinase 0.0549 0.0531 0.0906
Brugia malayi RhoGAP domain containing protein 0.0189 0.0015 0.0015
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0671 0.0704 0.0704
Loa Loa (eye worm) protein kinase domain-containing protein 0.0254 0.0108 0.0108
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.033 0.0217 0.0308
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0778 0.0857 0.4905
Entamoeba histolytica protein kinase, putative 0.0297 0.017 0.0811
Echinococcus multilocularis growth factor receptor bound protein 2 0.0286 0.0154 0.0262
Loa Loa (eye worm) hypothetical protein 0.0385 0.0296 0.0296
Onchocerca volvulus 0.0325 0.021 0.0578
Schistosoma mansoni serine/threonine protein kinase 0.0657 0.0684 0.0684
Echinococcus granulosus epidermal growth factor receptor 0.3042 0.4091 0.5811
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0384 0.0294 0.0502
Schistosoma mansoni serine/threonine protein kinase 0.1184 0.1437 0.1437
Loa Loa (eye worm) hypothetical protein 0.0574 0.0566 0.0566
Schistosoma mansoni tyrosine kinase 0.1179 0.143 0.143
Loa Loa (eye worm) hypothetical protein 0.039 0.0303 0.0303
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0766 0.084 0.084
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.0412 0.0412
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0678 0.0715 0.0715
Echinococcus multilocularis neuroglian 0.0469 0.0416 0.071
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1972 0.2563 0.3641
Schistosoma mansoni serine/threonine protein kinase 0.0568 0.0557 0.0557
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0403 0.0321 0.0321
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0309 0.0187 0.0919
Echinococcus granulosus Vam6:Vps39 protein 0.0251 0.0104 0.0148
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0403 0.0321 0.0321
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0939 0.1087 0.1544
Giardia lamblia Kinase, AGC AKT 0.0564 0.0552 0.2978
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.04 0.0317 0.1492
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.032 0.0202 0.1001
Echinococcus granulosus Diacylglycerol kinase theta 0.0189 0.0015 0.0022
Trypanosoma brucei casein kinase I, isoform 2 0.0403 0.0321 0.13
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0322 0.0205 0.035
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0251 0.0104 0.0104
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0345
Trichomonas vaginalis CMGC family protein kinase 0.0395 0.031 0.1411
Onchocerca volvulus Serine\/threonine kinase homolog 0.0392 0.0305 0.0839
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Onchocerca volvulus 0.0322 0.0205 0.0565
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0709 0.0758 0.1295
Brugia malayi Protein kinase domain containing protein 0.153 0.1931 0.1931
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0339 0.0229 0.0229
Trypanosoma cruzi casein kinase, putative 0.0403 0.0321 0.152
Echinococcus granulosus Rac GTPase activating protein 1 0.0189 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.1492 0.1878 0.1878
Echinococcus granulosus hypothetical protein 0.0234 0.008 0.0114
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1343 0.1664 0.284
Schistosoma mansoni serine/threonine protein kinase 0.1972 0.2563 0.2563
Brugia malayi ephrin receptor 1 precursor 0.0325 0.021 0.021
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1215 0.1481 0.2104
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0591 0.059 0.3215
Brugia malayi Temporarily assigned gene name protein 59 0.0655 0.0682 0.0682
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0573 0.0565 0.3057
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0457 0.0399 0.0399
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0199 0.0031 0.0044
Schistosoma mansoni rac gtpase activating protein 0.0189 0.0015 0.0015
Echinococcus granulosus serine/threonine protein kinase 0.0879 0.1002 0.1423
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0235 0.0081 0.0081
Echinococcus multilocularis expressed protein 0.0235 0.0081 0.0138
Brugia malayi Protein kinase domain containing protein 0.0591 0.059 0.059
Brugia malayi protein kinase C II. 0.0983 0.1149 0.1149
Echinococcus granulosus ephrin type A receptor 4 A 0.0497 0.0456 0.0647
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0287
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0755 0.0824 0.1407
Schistosoma mansoni hypothetical protein 0.039 0.0302 0.0302
Schistosoma mansoni vam6/vps39 related 0.0251 0.0104 0.0104
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0657 0.0684 0.0684
Loa Loa (eye worm) hypothetical protein 0.0322 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0384 0.0295 0.0295
Onchocerca volvulus 0.0251 0.0104 0.0286
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0395 0.031 0.124
Echinococcus granulosus serine:threonine kinase SAD 1 0.0318 0.02 0.0283
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0623 0.0636 0.0636
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.04 0.0317 0.1277
Echinococcus granulosus tyrosine kinase 0.0619 0.0631 0.0896
Echinococcus multilocularis dual specificity 0.024 0.0089 0.0152
Schistosoma mansoni protein kinase 0.1099 0.1315 0.1315
Trypanosoma brucei cdc2-related kinase 1 0.0573 0.0565 0.2616
Brugia malayi Immunoglobulin I-set domain containing protein 0.3116 0.4197 0.4197
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0286 0.0154 0.0154
Echinococcus multilocularis dual specificity protein kinase clk2 0.0371 0.0276 0.0472
Echinococcus multilocularis casein kinase i 0.0403 0.0321 0.0549
Trichomonas vaginalis AGC family protein kinase 0.0709 0.0758 0.3786
Schistosoma mansoni serine/threonine kinase 0.0788 0.0871 0.0871
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0407 0.0327 0.0464
Trypanosoma cruzi cdc2-related kinase 1 0.0573 0.0565 0.3057
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.04 0.0317 0.158
Entamoeba histolytica protein kinase, putative 0.0329 0.0215 0.1049
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0564 0.0552 0.0552
Entamoeba histolytica casein kinase, putative 0.0678 0.0715 0.3656
Brugia malayi hypothetical protein 0.0251 0.0104 0.0104
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0392 0.0305 0.0521
Schistosoma mansoni nephrin 0.0199 0.0031 0.0031
Echinococcus multilocularis neuroglian 0.0199 0.0031 0.0053
Trichomonas vaginalis CK1 family protein kinase 0.0403 0.0321 0.1469
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0755 0.0824 0.1407
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0099 0.0099
Echinococcus multilocularis c src tyrosine kinase 0.0457 0.0399 0.0681
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0297 0.0169 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0939 0.1087 0.1087
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.024 0.0089 0.0089
Leishmania major protein kinase, putative 0.0371 0.0276 0.1235
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1689 0.2159 0.2159
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.02 0.02
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0403 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0453 0.0394 0.0394
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0657 0.0684 0.381
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0591 0.059 0.2751
Loa Loa (eye worm) TK/FAK protein kinase 0.1165 0.141 0.141
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0392 0.0305 0.0434
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0384 0.0294 0.0418
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.0971
Loa Loa (eye worm) hypothetical protein 0.0766 0.084 0.084
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0788 0.0871 0.1237
Plasmodium falciparum serine/threonine protein kinase 0.0235 0.0081 0.0066
Schistosoma mansoni cell adhesion molecule 0.0199 0.0031 0.0031
Entamoeba histolytica protein kinase, putative 0.0407 0.0327 0.1632
Brugia malayi C1-like domain containing protein 0.0859 0.0973 0.0973
Echinococcus multilocularis protein kinase c eta type 0.0189 0.0015 0.0026
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0778 0.0857 0.4198
Brugia malayi Stress-activated protein kinase jnk-1 0.1312 0.162 0.162
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0619 0.0631 0.1077
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Entamoeba histolytica protein kinase, putative 0.0235 0.0081 0.0348
Loa Loa (eye worm) hypothetical protein 0.0286 0.0154 0.0154
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0819 0.0915 0.1562
Echinococcus granulosus tyrosine protein kinase shark 0.0322 0.0205 0.0292
Loa Loa (eye worm) thyroid receptor interactor 0.0275 0.0138 0.0138
Echinococcus granulosus protein tyrosine kinase 0.1153 0.1393 0.198
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0339 0.0229 0.0229
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0943 0.1093 0.1093
Echinococcus granulosus growth factor receptor bound protein 2 0.0286 0.0154 0.0218
Trichomonas vaginalis STE family protein kinase 0.04 0.0317 0.1446
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0318 0.02 0.075
Loa Loa (eye worm) hypothetical protein 0.0404 0.0323 0.0323
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0235 0.0081 0.0351
Brugia malayi Cam kinase protein 1 0.032 0.0202 0.0202
Echinococcus multilocularis calcium activated potassium channel 0.0527 0.0498 0.0851
Echinococcus granulosus N chimaerin 0.0339 0.0229 0.0326
Trichomonas vaginalis CK1 family protein kinase 0.0403 0.0321 0.1469
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0407 0.0327 0.0558
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0788 0.0871 0.1487
Schistosoma mansoni tyrosine kinase 0.2216 0.2911 0.2911
Brugia malayi Temporarily assigned gene name protein 59 0.0251 0.0104 0.0104
Schistosoma mansoni ste20-related kinase 0.1012 0.1191 0.1191
Brugia malayi Fibronectin type III domain containing protein 0.0406 0.0325 0.0325
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1312 0.162 0.162
Brugia malayi Protein kinase domain containing protein 0.0322 0.0205 0.0205
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.0971
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.032 0.0202 0.1631
Loa Loa (eye worm) AUR protein kinase 0.0709 0.0758 0.0758
Trichomonas vaginalis AGC family protein kinase 0.0709 0.0758 0.3786
Echinococcus multilocularis mitogen activated protein kinase 14 0.0778 0.0857 0.1463
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0591 0.059 0.3215
Entamoeba histolytica protein kinase domain containing protein 0.024 0.0089 0.0389
Schistosoma mansoni tyrosine kinase 0.0755 0.0824 0.0824
Entamoeba histolytica protein kinase, putative 0.0709 0.0758 0.3883
Schistosoma mansoni diacylglycerol kinase theta 0.0189 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0089 0.0236
Trypanosoma cruzi casein kinase, putative 0.0403 0.0321 0.152
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.7179 1 1
Echinococcus multilocularis myosin iiia 0.04 0.0317 0.0541
Schistosoma mansoni serine/threonine-protein kinase 0.0879 0.1002 0.1002
Brugia malayi Protein kinase domain containing protein 0.0949 0.1101 0.1101
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0504 0.0466 0.0662
Trypanosoma cruzi casein kinase, putative 0.0403 0.0321 0.152
Entamoeba histolytica protein kinase, putative 0.0326 0.0212 0.103
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0847 0.0956 1
Loa Loa (eye worm) hypothetical protein 0.0189 0.0015 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0199 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0827 0.0928 0.0928
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0827 0.0928 0.0928
Echinococcus granulosus casein kinase i 0.0403 0.0321 0.0457
Schistosoma mansoni hypothetical protein 0.039 0.0302 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0949 0.1101 0.1101
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Entamoeba histolytica cell division protein kinase 2, putative 0.0573 0.0565 0.2873
Plasmodium vivax unspecified product 0.0678 0.0715 0.7321
Brugia malayi Protein kinase domain containing protein 0.0322 0.0205 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0371 0.0276 0.123
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0309 0.0187 0.0672
Echinococcus multilocularis hypothetical protein 0.039 0.0302 0.0516
Echinococcus granulosus c src tyrosine kinase 0.0457 0.0399 0.0567
Giardia lamblia Kinase, NEK 0.0661 0.0691 0.3852
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1312 0.162 0.2766
Loa Loa (eye worm) hypothetical protein 0.0201 0.0034 0.0034
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0318 0.02 0.0642
Loa Loa (eye worm) hypothetical protein 0.0705 0.0753 0.0753
Trichomonas vaginalis CAMK family protein kinase 0.0297 0.0169 0.0664
Schistosoma mansoni cell adhesion molecule 0.0199 0.0031 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0294 0.1324
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0318 0.02 0.02
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0591 0.059 0.059
Leishmania major protein kinase, putative 0.04 0.0317 0.1492
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.037 0.0275 0.0275
Echinococcus multilocularis tyrosine protein kinase Srms 0.0619 0.0631 0.1077
Brugia malayi Protein kinase domain containing protein 0.0384 0.0294 0.0294
Echinococcus multilocularis death associated protein kinase 1 0.4279 0.5858 1
Schistosoma mansoni tyrosine kinase 0.0999 0.1173 0.1173
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0949 0.1101 0.3029
Entamoeba histolytica diacylglycerol kinase, putative 0.0189 0.0015 0.0006
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0199 0.0031 0.0031
Schistosoma mansoni tyrosine kinase 0.0331 0.0219 0.0219
Echinococcus granulosus serine threonine protein kinase nrc 0.0847 0.0956 0.1358
Entamoeba histolytica protein kinase, putative 0.033 0.0217 0.1057
Echinococcus multilocularis serine:threonine protein kinase N2 0.1039 0.123 0.21
Echinococcus granulosus twitchin 0.0606 0.0612 0.0869
Loa Loa (eye worm) hypothetical protein 0.039 0.0302 0.0302
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.062 0.3051
Brugia malayi RhoGEF domain containing protein 0.0189 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.02 0.02
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0395 0.031 0.145
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1375 0.171 0.2919
Trichomonas vaginalis AGC family protein kinase 0.0657 0.0684 0.3391
Entamoeba histolytica protein kinase, putative 0.0709 0.0758 0.3883
Echinococcus multilocularis Immunoglobulin 0.0384 0.0295 0.0503
Brugia malayi casein kinase I 0.0403 0.0321 0.0321
Schistosoma mansoni protein kinase 0.032 0.0202 0.0202
Toxoplasma gondii histone kinase SNF1, putative 0.0318 0.02 0.0986
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0309 0.0187 0.0672
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0466 0.0412 0.0412
Trichomonas vaginalis CMGC family protein kinase 0.0395 0.031 0.1411
Trichomonas vaginalis CMGC family protein kinase 0.0395 0.031 0.1411
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0195 0.0024 0.0035
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0847 0.0956 0.5529
Echinococcus granulosus calcium activated potassium channel 0.0527 0.0498 0.0708
Echinococcus granulosus contactin 0.0199 0.0031 0.0044
Echinococcus multilocularis raf serine:threonine protein kinase 0.036 0.026 0.0445
Schistosoma mansoni protein kinase 0.0403 0.0321 0.0321
Trypanosoma cruzi casein kinase II, putative 0.0678 0.0715 0.4005
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Echinococcus granulosus protein kinase c eta type 0.0189 0.0015 0.0022
Brugia malayi Protein kinase domain containing protein 0.0322 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0406 0.0325 0.0325
Echinococcus granulosus titin 0.0244 0.0094 0.0134
Trypanosoma cruzi casein kinase, putative 0.0403 0.0321 0.152
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0108 0.0108
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0657 0.0684 0.381
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.04 0.0317 0.158
Onchocerca volvulus 0.0322 0.0205 0.0565
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.1274 0.1566 0.1566
Loa Loa (eye worm) hypothetical protein 0.0195 0.0024 0.0024
Brugia malayi Protein kinase domain containing protein 0.0943 0.1093 0.1093
Echinococcus granulosus tyrosine protein kinase Srms 0.0322 0.0205 0.0292
Loa Loa (eye worm) hypothetical protein 0.0477 0.0427 0.0427
Echinococcus granulosus dual specificity 0.024 0.0089 0.0126
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.032 0.0202 0.1001
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0345 0.0239 0.0239
Trypanosoma brucei rac serine-threonine kinase, putative 0.153 0.1931 1
Brugia malayi map kinase activated protein kinase protein 2 0.1972 0.2563 0.2563
Echinococcus granulosus dual specificity 0.024 0.0089 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.1184 0.1437 0.1437
Echinococcus multilocularis mitogen activated protein kinase 11 0.0778 0.0857 0.1463
Echinococcus granulosus dual specificity 0.024 0.0089 0.0126
Entamoeba histolytica hypothetical protein 0.0591 0.059 0.3003
Loa Loa (eye worm) hypothetical protein 0.0729 0.0788 0.0788
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0318 0.02 0.075
Schistosoma mansoni tyrosine kinase 0.1813 0.2335 0.2335
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0819 0.0915 0.0915
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0244 0.0094 0.0094
Echinococcus multilocularis roundabout 2 0.0584 0.058 0.0989
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0089 0.0236
Echinococcus granulosus cGMP dependent protein kinase 0.0334 0.0224 0.0318
Schistosoma mansoni tyrosine kinase 0.3042 0.4091 0.4091
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.032 0.0202 0.1631
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1343 0.1664 1
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0705 0.0754 0.1286
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0859 0.0973 0.0973
Echinococcus granulosus Protein kinase C brain isozyme 0.1184 0.1437 0.2041
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0477 0.0427 0.0607
Schistosoma mansoni serine/threonine protein kinase 0.1343 0.1664 0.1664
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0089 0.0236
Loa Loa (eye worm) hypothetical protein 0.0189 0.0015 0.0015
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0371 0.0276 0.1235
Schistosoma mansoni tyrosine kinase 0.0322 0.0205 0.0205
Echinococcus granulosus protein kinase 0.037 0.0275 0.0391
Echinococcus granulosus casein kinase I delta 0.0403 0.0321 0.0457
Trypanosoma brucei polo-like protein kinase 0.1343 0.1664 0.8557
Onchocerca volvulus 0.0322 0.0205 0.0565
Schistosoma mansoni cell adhesion molecule 0.0499 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0562 0.0549 0.0549
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0318 0.02 0.0341
Brugia malayi Protein kinase domain containing protein 0.0686 0.0726 0.0726
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.024 0.0089 0.0089
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0949 0.1101 0.1101
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1984 0.258 0.3665
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.0224 0.0224
Trichomonas vaginalis AGC family protein kinase 0.0859 0.0973 0.4924
Echinococcus granulosus defective proboscis extension response 0.0384 0.0295 0.0418
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0447 0.0385 0.0385
Echinococcus multilocularis cyclin dependent kinase 5 0.0573 0.0565 0.0964
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0339 0.0229 0.0392
Loa Loa (eye worm) hypothetical protein 0.0895 0.1024 0.1024
Echinococcus granulosus cGMP dependent protein kinase 1 0.0334 0.0224 0.0318
Brugia malayi casein kinase 1, delta 0.0403 0.0321 0.0321
Echinococcus multilocularis aurora kinase A 0.0709 0.0758 0.1295
Schistosoma mansoni serine/threonine protein kinase 0.0395 0.031 0.031
Giardia lamblia Kinase, CMGC MAPK 0.0395 0.031 0.145
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0755 0.0824 0.1407
Trypanosoma brucei protein kinase, putative 0.0623 0.0636 0.3003
Trypanosoma brucei cdc2-related kinase 3 0.0573 0.0565 0.2616
Onchocerca volvulus 0.0283 0.015 0.0413
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0366 0.0269 0.0269
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0657 0.0684 0.6978
Echinococcus multilocularis serine:threonine protein kinase 3 0.1274 0.1566 0.2674
Entamoeba histolytica protein kinase domain containing protein 0.0623 0.0636 0.3247
Echinococcus multilocularis tyrosine protein kinase Abl 0.086 0.0974 0.1663
Loa Loa (eye worm) hypothetical protein 0.0705 0.0753 0.0753
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0099 0.0292
Echinococcus granulosus serine:threonine protein kinase 0.0549 0.0531 0.0754
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0847 0.0956 1
Loa Loa (eye worm) hypothetical protein 0.0251 0.0104 0.0104
Entamoeba histolytica casein kinase 1, putative 0.0403 0.0321 0.1603
Schistosoma mansoni protein kinase 0.032 0.0202 0.0202
Onchocerca volvulus 0.0322 0.0205 0.0565
Entamoeba histolytica PH domain containing protein kinase, putative 0.0689 0.073 0.3733
Echinococcus granulosus c-Jun N-terminal kinases 0.1312 0.162 0.2301
Toxoplasma gondii CMGC kinase, CK2 family 0.0678 0.0715 0.3741
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0395 0.031 0.031
Echinococcus multilocularis serine threonine protein kinase 0.0995 0.1168 0.1993
Echinococcus multilocularis protein tyrosine kinase 0.1153 0.1393 0.2379
Echinococcus granulosus tyrosine protein kinase Src42A 0.0755 0.0824 0.1171
Echinococcus granulosus casein kinase I alpha 0.0403 0.0321 0.0457
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1149 0.1387 0.1387
Echinococcus granulosus nervana 2 0.071 0.076 0.108
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0099 0.0099
Echinococcus granulosus RNA directed DNA polymerase 0.0201 0.0034 0.0048
Entamoeba histolytica protein kinase, putative 0.153 0.1931 1
Echinococcus multilocularis RNA directed DNA polymerase 0.0201 0.0034 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0661 0.0691 0.7052
Echinococcus multilocularis dual specificity testis specific protein kinase 0.1099 0.1315 0.2245
Brugia malayi Protein kinase domain containing protein 0.0901 0.1033 0.1033
Echinococcus granulosus CDC7 cell division cycle 7 0.0247 0.0099 0.0141
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0384 0.0294 0.0294
Echinococcus multilocularis NCK adaptor protein 0.0286 0.0154 0.0262
Echinococcus multilocularis 0.0234 0.008 0.0137
Echinococcus multilocularis casein kinase I delta 0.0403 0.0321 0.0549
Echinococcus multilocularis nervana 2 0.071 0.076 0.1297
Echinococcus multilocularis roundabout 2 0.0199 0.0031 0.0053
Entamoeba histolytica protein kinase, putative 0.033 0.0217 0.1057
Entamoeba histolytica diacylglycerol kinase, putative 0.0189 0.0015 0.0006
Loa Loa (eye worm) hypothetical protein 0.0325 0.021 0.021
Brugia malayi Ras association domain family 1 isoform A 0.0189 0.0015 0.0015
Loa Loa (eye worm) TK protein kinase 0.0619 0.0631 0.0631
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0287
Schistosoma mansoni vesicular amine transporter 0.0384 0.0295 0.0295
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0573 0.0565 0.0565
Echinococcus granulosus tyrosine kinase 0.0322 0.0205 0.0292
Echinococcus multilocularis Glutaredoxin protein 5 0.071 0.076 0.1297
Plasmodium falciparum casein kinase 1 0.0403 0.0321 0.2796
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0318 0.02 0.075
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus granulosus tyrosine protein kinase Lyn 0.0892 0.102 0.145
Schistosoma mansoni kinase 0.1436 0.1798 0.1798
Schistosoma mansoni hypothetical protein 0.0189 0.0015 0.0015
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.071 0.076 0.1297
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0504 0.0466 0.0466
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0345
Schistosoma mansoni ephrin receptor 0.0497 0.0456 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0466 0.0412 0.0412
Loa Loa (eye worm) AGC/AKT protein kinase 0.153 0.1931 0.1931
Brugia malayi serine/threonine-protein kinase PAK 7 0.1149 0.1387 0.1387
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.04 0.0317 0.1492
Echinococcus granulosus tyrosine protein kinase ABL1 0.1375 0.171 0.2429
Schistosoma mansoni serine/threonine protein kinase 0.033 0.0217 0.0217
Trypanosoma cruzi casein kinase, putative 0.0403 0.0321 0.152
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0519 0.0488 0.0693
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0403 0.0321 0.152
Trichomonas vaginalis AGC family protein kinase 0.0661 0.0691 0.3426
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0466 0.0412 0.0585
Loa Loa (eye worm) RasGEF domain-containing protein 0.0189 0.0015 0.0015
Brugia malayi putative serine/threonine kinase SADA gamma 0.0318 0.02 0.02
Echinococcus granulosus dual specificity testis-specific protein kinase 0.1099 0.1315 0.1868
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0371 0.0276 0.1235
Echinococcus granulosus protein kinase shaggy 0.0623 0.0636 0.0904
Loa Loa (eye worm) hypothetical protein 0.0234 0.008 0.008
Echinococcus multilocularis tyrosine protein kinase Blk 0.0619 0.0631 0.1077
Echinococcus granulosus Glutaredoxin protein 5 0.071 0.076 0.108
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0657 0.0684 0.326
Giardia lamblia Kinase, CAMK CAMKL 0.0318 0.02 0.075
Echinococcus granulosus tyrosine protein kinase HCK 0.047 0.0417 0.0592
Brugia malayi Kinase associated domain 1 family protein 0.039 0.0302 0.0302
Trypanosoma brucei aurora B kinase 0.0709 0.0758 0.3663
Loa Loa (eye worm) raf kinase 0.0189 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0722 0.0777 0.0777
Brugia malayi Protein kinase domain containing protein 0.0371 0.0276 0.0276
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0251 0.0104 0.0146
Entamoeba histolytica serine/threonine protein kinase, putative 0.0318 0.02 0.0967
Schistosoma mansoni serine/threonine protein kinase 0.1312 0.162 0.162
Echinococcus granulosus unc 13 munc13 0.0195 0.0024 0.0035
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0297 0.0169 0.0241
Entamoeba histolytica protein kinase 2, putative 0.0847 0.0956 0.4915
Loa Loa (eye worm) hypothetical protein 0.0754 0.0823 0.0823
Brugia malayi protein kinase C3,putative 0.0747 0.0813 0.0813
Echinococcus multilocularis epidermal growth factor receptor 0.1984 0.258 0.4405
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.062 0.3051
Brugia malayi phosphoinositide-dependent protein kinase I 0.0384 0.0294 0.0294
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0484 0.0437 0.0621
Trichomonas vaginalis CAMK family protein kinase 0.0297 0.0169 0.0664
Brugia malayi cell division control protein 2 homolog 0.0573 0.0565 0.0565
Echinococcus granulosus cyclin dependent kinase 5 0.0573 0.0565 0.0802
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0322 0.0205 0.0997
Trypanosoma cruzi cdc2-related kinase 1 0.0573 0.0565 0.3057
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0286 0.0154 0.0154
Echinococcus granulosus tyrosine protein kinase Fyn 0.0755 0.0824 0.1171
Onchocerca volvulus 0.0244 0.0094 0.0259
Giardia lamblia Kinase, PLK 0.1343 0.1664 1
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Echinococcus multilocularis PAK box P21 Rho binding 0.0297 0.017 0.0289
Plasmodium falciparum calcium-dependent protein kinase 3 0.032 0.0202 0.1445
Schistosoma mansoni protein kinase 0.037 0.0275 0.0275
Giardia lamblia Kinase, CMGC CDK 0.0573 0.0565 0.3057
Onchocerca volvulus 0.0322 0.0205 0.0565
Schistosoma mansoni tyrosine kinase 0.1813 0.2335 0.2335
Entamoeba histolytica p21-activated kinase 0.0439 0.0372 0.187
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0371 0.0276 0.1057
Loa Loa (eye worm) hypothetical protein 0.0657 0.0684 0.0684
Entamoeba histolytica protein kinase, putative 0.024 0.0089 0.0389
Onchocerca volvulus 0.0403 0.0321 0.0884
Loa Loa (eye worm) hypothetical protein 0.1237 0.1513 0.1513
Loa Loa (eye worm) TK/EGFR protein kinase 0.3042 0.4091 0.4091
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0266 0.0125 0.0281
Giardia lamblia Kinase, CK1 Casein kinase 0.0403 0.0321 0.152
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1032 0.122 0.2083
Loa Loa (eye worm) AGC/PKN protein kinase 0.1039 0.123 0.123
Schistosoma mansoni serine/threonine protein kinase 0.036 0.026 0.026
Loa Loa (eye worm) TK/EPH protein kinase 0.0586 0.0583 0.0583
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0287 0.0156 0.0741
Trichomonas vaginalis CMGC family protein kinase 0.0573 0.0565 0.2759
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Brugia malayi Protein kinase domain containing protein 0.0235 0.0081 0.0081
Leishmania major protein kinase, putative 0.032 0.0202 0.0767
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.032 0.0202 0.1631
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3116 0.4197 0.4197
Schistosoma mansoni serine/threonine protein kinase 0.0709 0.0758 0.0758
Trichomonas vaginalis CMGC family protein kinase 0.0623 0.0636 0.3139
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0657 0.0684 0.381
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Brugia malayi SH2 domain containing protein 0.0322 0.0205 0.0205
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0384 0.0295 0.0295
Brugia malayi hypothetical protein 0.0504 0.0466 0.0466
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0334 0.0224 0.0382
Echinococcus multilocularis expressed conserved protein 0.0334 0.0224 0.0382
Trichomonas vaginalis STE family protein kinase 0.0407 0.0327 0.1498
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0247 0.0099 0.0116
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0395 0.031 0.1578
Echinococcus granulosus mitogen activated protein kinase 0.0395 0.031 0.0441
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0657 0.0684 0.326
Schistosoma mansoni serine/threonine protein kinase 0.0823 0.0921 0.0921
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.032 0.0202 0.0657
Echinococcus granulosus casein kinase I gamma 0.0254 0.0108 0.0154
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0949 0.1101 0.1565
Giardia lamblia Kinase, AGC PKA 0.0657 0.0684 0.381
Loa Loa (eye worm) CAMK protein kinase 0.0244 0.0094 0.0094
Brugia malayi Fes/CIP4 homology domain containing protein 0.0275 0.0138 0.0138
Brugia malayi Egg laying defective protein 4 0.0334 0.0224 0.0224
Echinococcus multilocularis Immunoglobulin 0.0384 0.0295 0.0503
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1237 0.1513 0.1513
Echinococcus granulosus epidermal growth factor receptor 0.1984 0.258 0.3665
Onchocerca volvulus 0.0247 0.0099 0.0273
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0089 0.0089
Echinococcus multilocularis roundabout 2 0.0199 0.0031 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0939 0.1087 0.1087
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0339 0.0229 0.0229
Echinococcus multilocularis 0.0882 0.1006 0.1717
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0466 0.0412 0.0412
Brugia malayi Serine/threonine-protein kinase SULU 0.0504 0.0466 0.0466
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0395 0.031 0.145
Brugia malayi P38 map kinase family protein 2 0.0778 0.0857 0.0857
Brugia malayi RhoGAP domain containing protein 0.0339 0.0229 0.0229
Leishmania major protein kinase A catalytic subunit isoform 2 0.0657 0.0684 0.381
Schistosoma mansoni serine/threonine protein kinase 0.0657 0.0684 0.0684
Plasmodium falciparum serine/threonine protein kinase, putative 0.0709 0.0758 0.7756
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0678 0.0715 0.7321
Plasmodium falciparum protein serine/threonine kinase-1 0.0371 0.0276 0.2284
Brugia malayi Protein kinase domain containing protein 0.0631 0.0647 0.0647
Plasmodium falciparum cGMP-dependent protein kinase 0.0334 0.0224 0.1685
Entamoeba histolytica serine/threonine protein kinase, putative 0.1343 0.1664 0.8607
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0247 0.0099 0.0099
Echinococcus granulosus tyrosine protein kinase Fyn 0.0755 0.0824 0.1171
Echinococcus multilocularis serine:threonine protein kinase 38 0.0788 0.0871 0.1487
Brugia malayi Tyrosine-protein kinase abl-1 0.086 0.0974 0.0974
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0247 0.0099 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0709 0.0758 0.3786
Echinococcus multilocularis titin 0.0244 0.0094 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0657 0.0684 0.0684
Brugia malayi Protein kinase domain containing protein 0.4754 0.6537 0.6537
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.0321 0.0321
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Toxoplasma gondii casein kinase I 0.0403 0.0321 0.1638
Brugia malayi p70 ribosomal S6 kinase beta 0.1498 0.1885 0.1885
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Trypanosoma brucei SNF1-related protein kinases, putative 0.0318 0.02 0.0642
Plasmodium falciparum serine/threonine protein kinase KIN 0.0318 0.02 0.1413
Onchocerca volvulus 0.0623 0.0636 0.175
Schistosoma mansoni atypical protein kinase C 0.1428 0.1786 0.1786
Brugia malayi Protein kinase domain containing protein 0.0447 0.0385 0.0385
Echinococcus granulosus nervana 2 0.071 0.076 0.108
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0766 0.084 0.1435
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0371 0.0276 0.1396
Echinococcus granulosus dual specificity protein kinase clk2 0.0371 0.0276 0.0393
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0788 0.0871 0.1237
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1135 0.1367 0.1941
Trichomonas vaginalis CAMK family protein kinase 0.0686 0.0726 0.3614
Brugia malayi Tyrosine-protein kinase abl-1 0.0651 0.0675 0.0675
Echinococcus granulosus neuroglian 0.0469 0.0416 0.0591
Brugia malayi Protein kinase domain containing protein 0.0193 0.0022 0.0022
Plasmodium vivax calcium-dependent protein kinase, putative 0.032 0.0202 0.1631
Echinococcus multilocularis casein kinase ii subunit alpha 0.0678 0.0715 0.122
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.0971
Loa Loa (eye worm) TK protein kinase 0.047 0.0417 0.0417
Loa Loa (eye worm) CDC7 protein kinase 0.0247 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.0329 0.0215 0.1049
Echinococcus multilocularis rho associated protein kinase 0.1621 0.2062 0.352
Entamoeba histolytica PH domain containing protein kinase, putative 0.0879 0.1002 0.5153
Loa Loa (eye worm) hypothetical protein 0.0436 0.0369 0.0369
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0199 0.0031 0.0053
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1179 0.143 0.244
Onchocerca volvulus Serine\/threonine kinase homolog 0.1343 0.1664 0.4575
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1215 0.1481 0.1481
Loa Loa (eye worm) hypothetical protein 0.032 0.0202 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.024 0.0089 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0807 0.0899 0.0899
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0705 0.0754 0.1071
Loa Loa (eye worm) SRC-1 0.0755 0.0824 0.0824
Brugia malayi hypothetical protein 0.0367 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0604 0.0609 0.0609
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0395 0.031 0.145
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0189 0.0015 0.0015
Leishmania major protein kinase A catalytic subunit isoform 1 0.0657 0.0684 0.381
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.1167
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0286 0.0154 0.0154
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0407 0.0327 0.0464
Loa Loa (eye worm) hypothetical protein 0.0182 0.0006 0.0006
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0504 0.0466 0.0796
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0407 0.0327 0.0558
Schistosoma mansoni tyrosine kinase 0.0457 0.0399 0.0399
Leishmania major protein kinase A catalytic subunit 0.0657 0.0684 0.381
Toxoplasma gondii AGC kinase 0.0657 0.0684 0.3576
Plasmodium vivax protein kinase Crk2 0.0573 0.0565 0.5655
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0847 0.0956 0.1632
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0371 0.0276 0.1235
Schistosoma mansoni serine/threonine-protein kinase 0.0879 0.1002 0.1002
Brugia malayi Variant SH3 domain containing protein 0.0339 0.0229 0.0229
Echinococcus multilocularis calcium dependent protein kinase 0.0182 0.0006 0.0011
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0257 0.0112 0.0192
Echinococcus multilocularis dual specificity 0.024 0.0089 0.0152
Schistosoma mansoni tyrosine kinase 0.035 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0189 0.0015 0.0015
Schistosoma mansoni protein kinase 0.032 0.0202 0.0202
Giardia lamblia Kinase, AGC PKA 0.0847 0.0956 0.5529
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0709 0.0758 0.3883
Loa Loa (eye worm) hypothetical protein 0.0549 0.0531 0.0531
Trichomonas vaginalis STE family protein kinase 0.0407 0.0327 0.1498
Echinococcus multilocularis twitchin 0.0222 0.0063 0.0108
Brugia malayi diacylglycerol kinase 0.0189 0.0015 0.0015
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Leishmania major protein kinase, putative 0.0709 0.0758 0.428
Entamoeba histolytica protein kinase domain containing protein 0.0709 0.0758 0.3883
Echinococcus granulosus mitogen activated protein kinase 14 0.0778 0.0857 0.1218
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0573 0.0565 0.2939
Trypanosoma brucei protein kinase, putative 0.0395 0.031 0.124
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.023 0.0075 0.032
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0755 0.0824 0.1171
Schistosoma mansoni rap gtpase-activating protein 0.0251 0.0104 0.0104
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0334 0.0224 0.0382
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0337 0.0227 0.0227
Echinococcus granulosus mitogen activated protein kinase 11 0.0778 0.0857 0.1218
Brugia malayi Protein kinase domain containing protein 0.0254 0.0108 0.0108
Toxoplasma gondii AGC kinase 0.0657 0.0684 0.3576
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0318 0.02 0.16
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0619 0.0631 0.0896
Brugia malayi serine/threonine-protein kinase plk-2 0.1343 0.1664 0.1664
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0847 0.0956 0.1358
Echinococcus granulosus expressed protein 0.0235 0.0081 0.0115
Trichomonas vaginalis AGC family protein kinase 0.0788 0.0871 0.4382
Plasmodium falciparum casein kinase 2, alpha subunit 0.0678 0.0715 0.7261
Brugia malayi Protein kinase domain containing protein 0.0322 0.0205 0.0205
Echinococcus granulosus casein kinase I alpha 0.0403 0.0321 0.0457
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Schistosoma mansoni protein kinase C mu 0.0189 0.0015 0.0015
Onchocerca volvulus 0.1484 0.1866 0.513
Schistosoma mansoni protein kinase 0.0709 0.0758 0.0758
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0251 0.0104 0.0125
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.024 0.0089 0.005
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0202 0.0838
Brugia malayi hypothetical protein 0.018 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.1039 0.123 0.123
Schistosoma mansoni protein kinase 0.0447 0.0385 0.0385
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0089 0.0236
Echinococcus granulosus myotubularin protein 13 0.0221 0.0061 0.0086
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.4754 0.6537 0.6537
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0143 0.5
Brugia malayi probable protein kinase 0.0621 0.0633 0.0633
Echinococcus multilocularis insulin receptor 0.2216 0.2911 0.4969
Schistosoma mansoni tyrosine kinase 0.1153 0.1393 0.1393
Echinococcus granulosus serine:threonine protein kinase 0.0549 0.0531 0.0754
Echinococcus granulosus cyclin dependent kinase 0.0573 0.0565 0.0802
Schistosoma mansoni nck2/grb4 0.0286 0.0154 0.0154
Loa Loa (eye worm) TK/ROR protein kinase 0.0257 0.0112 0.0112
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0755 0.0824 0.1407
Loa Loa (eye worm) hypothetical protein 0.0562 0.0549 0.0549
Echinococcus granulosus activin receptor type 0.0309 0.0187 0.0266
Echinococcus multilocularis peroxidasin 0.0179 0.0002 0.0003
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0949 0.1101 0.188
Schistosoma mansoni tyrosine kinase 0.0755 0.0824 0.0824
Echinococcus granulosus roundabout 2 0.0199 0.0031 0.0044
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0949 0.1101 0.1101
Brugia malayi intracellular kinase 0.0623 0.0636 0.0636
Brugia malayi Protein kinase domain containing protein 0.0819 0.0915 0.0915
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0766 0.084 0.1194
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0094 0.0094
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0623 0.0636 0.1086
Echinococcus multilocularis nervana 2 0.071 0.076 0.1297
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0384 0.0295 0.0295
Echinococcus granulosus Immunoglobulin 0.0384 0.0295 0.0418
Echinococcus multilocularis CDC7 cell division cycle 7 0.0247 0.0099 0.017
Loa Loa (eye worm) hypothetical protein 0.0533 0.0508 0.0508
Echinococcus granulosus insulin growth factor 1 receptor beta 0.2237 0.2942 0.4179
Entamoeba histolytica protein kinase, putative 0.0235 0.0081 0.0348
Trypanosoma cruzi p21-activated kinase 3, putative 0.0247 0.0099 0.0116
Brugia malayi hypothetical protein 0.0322 0.0205 0.0205
Trichomonas vaginalis AGC family protein kinase 0.0709 0.0758 0.3786
Entamoeba histolytica protein kinase domain containing protein 0.0591 0.059 0.3003
Schistosoma mansoni serine/threonine protein kinase 0.7179 1 1
Loa Loa (eye worm) AUR protein kinase 0.0709 0.0758 0.0758
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0807 0.0899 0.1277
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0371 0.0276 0.1235
Entamoeba histolytica protein kinase domain containing protein 0.0466 0.0412 0.2076
Onchocerca volvulus 0.0754 0.0823 0.2262
Schistosoma mansoni growth factor receptor-bound protein 0.0286 0.0154 0.0154
Giardia lamblia Kinase, CAMK CAMKL 0.0318 0.02 0.075
Entamoeba histolytica protein kinase, putative 0.0591 0.059 0.3003
Entamoeba histolytica protein kinase, putative 0.047 0.0417 0.21
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Loa Loa (eye worm) AUR protein kinase 0.0709 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.0406 0.0325 0.0325
Echinococcus granulosus casein kinase I alpha 0.0403 0.0321 0.0457
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0099 0.0292
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1179 0.143 0.2031
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Brugia malayi Peroxidasin 0.0179 0.0002 0.0002
Schistosoma mansoni protein kinase C mu 0.0859 0.0973 0.0973
Loa Loa (eye worm) TK/INSR protein kinase 0.2216 0.2911 0.2911
Brugia malayi Protein kinase domain containing protein 0.2216 0.2911 0.2911
Echinococcus multilocularis mitogen activated protein kinase 0.0395 0.031 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.059 0.059
Leishmania major casein kinase, putative 0.0403 0.0321 0.152
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.02 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0623 0.0636 0.3247
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0657 0.0684 0.326
Schistosoma mansoni protein kinase 0.0297 0.017 0.017
Entamoeba histolytica PH domain containing protein kinase, putative 0.0879 0.1002 0.5153
Giardia lamblia Kinase, NEK 0.0661 0.0691 0.3852
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1135 0.1367 0.2333
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0709 0.0758 0.1077
Brugia malayi Furin-like cysteine rich region family protein 0.3042 0.4091 0.4091
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0686 0.0726 0.0726
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus multilocularis rac serine:threonine kinase 0.0879 0.1002 0.171
Brugia malayi Immunoglobulin I-set domain containing protein 0.0199 0.0031 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0573 0.0565 0.2759
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0251 0.0104 0.0104
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0657 0.0684 0.691
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0199 0.0031 0.0053
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0591 0.059 0.3215
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0384 0.0295 0.0503
Echinococcus multilocularis N chimaerin 0.0339 0.0229 0.0392
Entamoeba histolytica PH domain containing protein kinase, putative 0.0689 0.073 0.3733
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.069 0.0731 0.3643
Loa Loa (eye worm) hypothetical protein 0.0484 0.0437 0.0437
Onchocerca volvulus Tyrosine kinase homolog 0.2724 0.3637 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0879 0.1002 0.5818
Brugia malayi protein unc-22 0.0244 0.0094 0.0094
Brugia malayi Protein kinase domain containing protein 0.093 0.1074 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.0498 0.0498
Schistosoma mansoni diacylglycerol kinase theta 0.0189 0.0015 0.0015
Giardia lamblia Kinase, CMGC CDK 0.0573 0.0565 0.3057
Loa Loa (eye worm) hypothetical protein 0.0189 0.0015 0.0015
Echinococcus granulosus calcium dependent protein kinase 0.0182 0.0006 0.0009
Trypanosoma cruzi Protein kinase B 0.0879 0.1002 0.5818
Brugia malayi Casein kinase II, alpha chain 0.0678 0.0715 0.0715
Brugia malayi protein-tyrosine kinase 0.0619 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0367 0.027 0.027
Entamoeba histolytica protein kinase domain containing protein 0.0678 0.0715 0.3656
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0623 0.0636 0.3322
Toxoplasma gondii aurora kinase 0.0709 0.0758 0.3974
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.071 0.076 0.108
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0395 0.031 0.145
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0949 0.1101 0.1101
Schistosoma mansoni unc-13 (munc13) 0.0195 0.0024 0.0024
Plasmodium falciparum calcium-dependent protein kinase 2 0.032 0.0202 0.1445
Echinococcus granulosus protein kinase c iota type 0.1397 0.1742 0.2474
Echinococcus multilocularis activin receptor type 0.0309 0.0187 0.0319
Loa Loa (eye worm) hypothetical protein 0.0179 0.0002 0.0002
Brugia malayi serine/threonine protein kinase 6 0.0709 0.0758 0.0758
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1237 0.1513 0.1513
Entamoeba histolytica protein kinase, putative 0.0287 0.0156 0.0741
Onchocerca volvulus 0.0195 0.0024 0.0067
Loa Loa (eye worm) TK/ABL protein kinase 0.1375 0.171 0.171
Plasmodium falciparum protein kinase 5 0.0573 0.0565 0.5558
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.0224 0.0224
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0251 0.0104 0.0146
Brugia malayi serine/threonine-protein kinase 6 0.0709 0.0758 0.0758
Schistosoma mansoni protein kinase 0.0407 0.0327 0.0327
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Echinococcus multilocularis casein kinase I alpha 0.0403 0.0321 0.0549
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0623 0.0636 0.3509
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.032 0.0202 0.0202
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.032 0.0202 0.1001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0199 0.0031 0.0031
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0596 0.0598 0.3266
Echinococcus multilocularis myotubularin protein 13 0.0221 0.0061 0.0104
Entamoeba histolytica cell division protein kinase 2, putative 0.0573 0.0565 0.2873
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1215 0.1481 0.2528
Schistosoma mansoni serine/threonine protein kinase 0.0788 0.0871 0.0871
Schistosoma mansoni vav2 0.037 0.0275 0.0275
Plasmodium falciparum NIMA related kinase 1 0.0661 0.0691 0.6986
Schistosoma mansoni hypothetical protein 0.0251 0.0104 0.0104
Giardia lamblia Kinase, STE STE20 0.04 0.0317 0.1492
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.033 0.0217 0.037
Trichomonas vaginalis CMGC family protein kinase 0.0623 0.0636 0.3139
Brugia malayi Protein kinase domain containing protein 0.0322 0.0205 0.0205
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0407 0.0327 0.0464
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1498 0.1885 0.1885
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0089 0.0236
Echinococcus multilocularis mitogen activated protein kinase 3 0.0395 0.031 0.053
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0623 0.0636 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.032 0.0202 0.0202
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0657 0.0684 0.381
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0395 0.031 0.145
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0081 0.0081
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0623 0.0636 0.0636
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Trypanosoma cruzi cdc2-related kinase 3 0.0573 0.0565 0.3057
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.0498 0.0498
Brugia malayi Protein kinase domain containing protein 0.1237 0.1513 0.1513
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0709 0.0758 0.3883
Brugia malayi Protein kinase domain containing protein 0.0788 0.0871 0.0871
Schistosoma mansoni neuroglian 0.0199 0.0031 0.0031
Schistosoma mansoni tyrosine kinase 0.0457 0.0399 0.0399
Schistosoma mansoni protein kinase 0.0621 0.0633 0.0633
Echinococcus granulosus rho-associated protein kinase 1 0.1621 0.2062 0.2929
Echinococcus granulosus casein kinase ii subunit alpha 0.0678 0.0715 0.1015
Onchocerca volvulus 0.0247 0.0099 0.0273
Leishmania major protein kinase, putative 0.0309 0.0187 0.0672
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0371 0.0276 0.1057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0345
Brugia malayi Immunoglobulin I-set domain containing protein 0.1264 0.1551 0.1551
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0623 0.0636 0.3509
Loa Loa (eye worm) hypothetical protein 0.0251 0.0104 0.0104
Echinococcus multilocularis cyclin dependent kinase 1 0.0573 0.0565 0.0964
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0388 0.03 0.0426
Plasmodium falciparum calcium-dependent protein kinase 4 0.032 0.0202 0.1445
Echinococcus multilocularis unc 13 (munc13) 0.0195 0.0024 0.0042
Echinococcus multilocularis mitogen activated protein kinase 11 0.0778 0.0857 0.1463
Loa Loa (eye worm) hypothetical protein 0.0384 0.0295 0.0295
Echinococcus granulosus neuroglian 0.0199 0.0031 0.0044
Echinococcus granulosus raf serine:threonine protein kinase 0.036 0.026 0.037
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0755 0.0824 0.1407
Brugia malayi Variant SH3 domain containing protein 0.0286 0.0154 0.0154
Schistosoma mansoni protein kinase C 0.0195 0.0024 0.0024
Onchocerca volvulus 0.0722 0.0777 0.2137
Echinococcus multilocularis tyrosine protein kinase shark 0.0322 0.0205 0.035
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0334 0.0224 0.1114
Plasmodium falciparum glycogen synthase kinase 3 0.0623 0.0636 0.6371
Trichomonas vaginalis CAMK family protein kinase 0.0318 0.02 0.0824
Giardia lamblia Aurora kinase 0.0709 0.0758 0.428
Echinococcus granulosus serine:threonine protein kinase N2 0.0252 0.0105 0.0149
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.0294 0.0294
Brugia malayi Protein kinase domain containing protein 0.0247 0.0099 0.0099
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1184 0.1437 0.2453
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0807 0.0899 0.1535
Entamoeba histolytica protein kinase, putative 0.153 0.1931 1
Schistosoma mansoni protein kinase 0.0309 0.0187 0.0187
Schistosoma mansoni tyrosine kinase 0.1225 0.1496 0.1496
Brugia malayi Immunoglobulin I-set domain containing protein 0.0244 0.0094 0.0094
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0294 0.1324
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0549 0.0531 0.0531
Schistosoma mansoni protein kinase 0.1099 0.1315 0.1315
Schistosoma mansoni protein kinase 0.0819 0.0915 0.0915
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1972 0.2563 0.4375
Echinococcus granulosus NDR protein kinase 0.0788 0.0871 0.1237
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0199 0.0031 0.0053
Trypanosoma brucei protein kinase, putative 0.0309 0.0187 0.0575
Plasmodium vivax casein kinase 1, putative 0.0403 0.0321 0.2953
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0573 0.0565 0.3057
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0199 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0392 0.0305 0.0305
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.024 0.0089 0.0393
Brugia malayi Pleckstrin Homology Domain 0.0221 0.0061 0.0061
Schistosoma mansoni protein kinase 0.0407 0.0327 0.0327
Onchocerca volvulus 0.0322 0.0205 0.0565
Brugia malayi serine/threonine kinase 12 0.0709 0.0758 0.0758
Brugia malayi STE20-like kinase MST 0.1274 0.1566 0.1566
Plasmodium vivax serine/threonine protein kinase, putative 0.0235 0.0081 0.0282
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0466 0.0412 0.0703
Echinococcus multilocularis 0.037 0.0275 0.0469
Plasmodium vivax glycogen synthase kinase 3, putative 0.0623 0.0636 0.645
Brugia malayi Doublecortin family protein 0.0366 0.0269 0.0269
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0778 0.0857 0.0857
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.032 0.0202 0.0345
Giardia lamblia Kinase, CMGC GSK 0.0623 0.0636 0.3509
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0823 0.0921 0.1309
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0755 0.0824 0.1407
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0755 0.0824 0.1407
Loa Loa (eye worm) hypothetical protein 0.018 0.0004 0.0004
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0807 0.0899 0.0899
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0189 0.0015 0.0015
Echinococcus multilocularis cyclin dependent kinase 0.0573 0.0565 0.0964
Schistosoma mansoni serine/threonine protein kinase 0.0983 0.1149 0.1149
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.0498 0.0498
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0657 0.0684 0.1167
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0573 0.0565 0.0802
Echinococcus multilocularis casein kinase I delta 0.0403 0.0321 0.0549
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0939 0.1087 0.1856
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1972 0.2563 0.2563
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.033 0.0217 0.037
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0819 0.0915 0.13
Entamoeba histolytica hypothetical protein 0.0737 0.0799 0.4095
Echinococcus granulosus tyrosine protein kinase Src42A 0.0448 0.0386 0.0548
Loa Loa (eye worm) hypothetical protein 0.0269 0.0131 0.0131
Echinococcus multilocularis dual specificity 0.0591 0.059 0.1007
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0407 0.0327 0.0558
Echinococcus granulosus peroxidasin 0.0179 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0453 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0189 0.0015 0.0015
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0188 0.0015 0.0015
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0448 0.0386 0.0658
Echinococcus granulosus titin 0.0244 0.0094 0.0134
Brugia malayi Protein kinase domain containing protein 0.1165 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0221 0.0061 0.0061
Entamoeba histolytica protein kinase domain containing protein 0.0309 0.0187 0.0903
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.02 0.02
Echinococcus granulosus casein kinase I delta 0.0403 0.0321 0.0457
Brugia malayi Variant SH3 domain containing protein 0.0188 0.0015 0.0015
Echinococcus multilocularis casein kinase I alpha 0.0403 0.0321 0.0549
Giardia lamblia Kinase, CMGC CK2 0.0678 0.0715 0.4005
Echinococcus granulosus serine:threonine protein kinase Chk2 0.033 0.0217 0.0308
Entamoeba histolytica protein kinase, putative 0.0591 0.059 0.3003
Echinococcus multilocularis Diacylglycerol kinase theta 0.0189 0.0015 0.0026
Leishmania major protein kinase, putative 0.0371 0.0276 0.1235
Schistosoma mansoni tyrosine kinase 0.1984 0.258 0.258
Trichomonas vaginalis CMGC family protein kinase 0.0678 0.0715 0.3555
Echinococcus granulosus cGMP dependent protein kinase 1 0.0334 0.0224 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0788 0.0871 0.1487
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0195 0.0024 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0827 0.0928 0.4682
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.1343 0.1664 0.8585
Loa Loa (eye worm) TK/FER protein kinase 0.0322 0.0205 0.0205
Echinococcus granulosus NCK adaptor protein 0.0286 0.0154 0.0218
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0939 0.1087 0.1544
Trichomonas vaginalis STE family protein kinase 0.0407 0.0327 0.1498
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0989 0.1159 0.1647
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.032 0.0202 0.0287
Mycobacterium ulcerans hypothetical protein 0.0197 0.0027 0.5
Echinococcus granulosus tyrosine protein kinase Src64B 0.0755 0.0824 0.1171
Brugia malayi diacylglycerol kinase 0.0189 0.0015 0.0015
Echinococcus granulosus dual specificity 0.0591 0.059 0.0838
Trichomonas vaginalis STE family protein kinase 0.0661 0.0691 0.3426
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5106 0.704 1
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0318 0.02 0.075
Trichomonas vaginalis CK1 family protein kinase 0.0403 0.0321 0.1469
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0257 0.0112 0.016
Loa Loa (eye worm) AGC/PKA protein kinase 0.0657 0.0684 0.0684
Loa Loa (eye worm) hypothetical protein 0.0189 0.0015 0.0015
Entamoeba histolytica protein kinase, putative 0.1498 0.1885 0.9762
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0755 0.0824 0.1171
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0099 0.0099
Schistosoma mansoni tyrosine kinase 0.1813 0.2335 0.2335
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0573 0.0565 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0063 0.0063
Echinococcus granulosus protein kinase c epsilon type 0.0983 0.1149 0.1633
Trichomonas vaginalis AGC family protein kinase 0.153 0.1931 1
Onchocerca volvulus 0.0533 0.0508 0.1396
Schistosoma mansoni tyrosine kinase 0.1984 0.258 0.258
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0392 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0788 0.0871 0.0871
Toxoplasma gondii AGC kinase 0.1498 0.1885 1
Entamoeba histolytica casein kinase, putative 0.0403 0.0321 0.1603
Brugia malayi Hr1 repeat family protein 0.1039 0.123 0.123
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0395 0.031 0.145
Trypanosoma cruzi cdc2-related kinase 3 0.0573 0.0565 0.3057
Loa Loa (eye worm) AGC/PKG protein kinase 0.0334 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0367 0.027 0.027
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0983 0.1149 0.1149
Echinococcus granulosus roundabout 2 0.0199 0.0031 0.0044
Schistosoma mansoni tyrosine kinase 0.2216 0.2911 0.2911
Brugia malayi Immunoglobulin I-set domain containing protein 0.0406 0.0325 0.0325
Trichomonas vaginalis AGC family protein kinase 0.0827 0.0928 0.4682
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0251 0.0104 0.0178
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0823 0.0921 0.1572
Trichomonas vaginalis STE family protein kinase 0.0407 0.0327 0.1498
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0989 0.1159 0.1979
Giardia lamblia Kinase, CMGC CLK 0.0371 0.0276 0.1235
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0778 0.0857 0.4905
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1343 0.1664 0.1664

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.7079 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 6.7456 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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