Detailed information for compound 1355738

Basic information

Technical information
  • TDR Targets ID: 1355738
  • Name: 2-ethylsulfanyl-4-(5-methylfuran-2-yl)-6-oxo- 4,5-dihydro-1H-pyridine-3-carbonitrile
  • MW: 262.327 | Formula: C13H14N2O2S
  • H donors: 1 H acceptors: 2 LogP: 1.42 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCSC1=C(C#N)C(CC(=O)N1)c1ccc(o1)C
  • InChi: 1S/C13H14N2O2S/c1-3-18-13-10(7-14)9(6-12(16)15-13)11-5-4-8(2)17-11/h4-5,9H,3,6H2,1-2H3,(H,15,16)
  • InChiKey: JEWOUWCNKJLSOO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-ethylsulfanyl-4-(5-methyl-2-furyl)-6-oxo-4,5-dihydro-1H-pyridine-3-carbonitrile
  • 2-(ethylthio)-4-(5-methyl-2-furyl)-6-oxo-4,5-dihydro-1H-pyridine-3-carbonitrile
  • 2-(ethylthio)-6-keto-4-(5-methyl-2-furyl)-4,5-dihydro-1H-pyridine-3-carbonitrile
  • AG-690/12888733
  • STOCK1S-29108
  • 2-Ethylsulfanyl-4-(5-methyl-furan-2-yl)-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carbonitrile
  • MLS001029986
  • SMR000427209

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens snurportin 1 No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.0432 0.0249 0.1853
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0104 0.0104
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0613 0.0467 0.0466
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0485 0.0312 0.0312
Trichomonas vaginalis CMGC family protein kinase 0.0336 0.0131 0.0818
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.2036 0.2191 0.2189
Echinococcus granulosus cGMP dependent protein kinase 1 0.0485 0.0312 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Echinococcus granulosus serine:threonine protein kinase N2 0.2147 0.2324 0.2324
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0098 0.0098
Brugia malayi protein kinase C II. 0.1023 0.0964 0.0964
Schistosoma mansoni tyrosine kinase 0.0849 0.0753 0.0753
Echinococcus granulosus tyrosine protein kinase csk 0.0294 0.0081 0.0081
Echinococcus granulosus serine:threonine protein kinase N2 0.1396 0.1415 0.1415
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Toxoplasma gondii histone kinase SNF1, putative 0.0453 0.0274 0.1862
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0294 0.0081 0.0081
Echinococcus granulosus ephrin type A receptor 4 A 0.0507 0.034 0.034
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0432 0.0249 0.0247
Schistosoma mansoni protein tyrosine kinase 0.0294 0.0081 0.0081
Toxoplasma gondii CMGC kinase, CK2 family 0.037 0.0173 0.0888
Plasmodium falciparum calcium-dependent protein kinase 5 0.0372 0.0176 0.1369
Loa Loa (eye worm) hypothetical protein 0.1352 0.1362 0.136
Echinococcus granulosus integrin linked protein kinase 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.233 0.2546 0.2546
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Echinococcus granulosus snurportin 1 0.0372 0.0175 0.0175
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Entamoeba histolytica cysteine surface protein, putative 0.0294 0.0081 0.0634
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1131 0.1095 0.1095
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.034 0.0137 0.0137
Brugia malayi Protein kinase domain containing protein 0.0867 0.0774 0.0774
Entamoeba histolytica serine/threonine kinase, putative 0.0294 0.0081 0.0634
Schistosoma mansoni protein kinase 0.3123 0.3506 0.3506
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0717 0.0594 0.4951
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0294 0.0081 0.0375
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0706 0.0579 0.0579
Echinococcus granulosus epidermal growth factor receptor 0.5971 0.6955 0.6955
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0615 0.0469 0.0469
Entamoeba histolytica hypothetical protein 0.1267 0.1259 1
Loa Loa (eye worm) TK protein kinase 0.2357 0.2579 0.2578
Schistosoma mansoni tyrosine kinase 0.1828 0.1938 0.1938
Echinococcus multilocularis tyrosine protein kinase shark 0.2472 0.2718 0.2718
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.2036 0.2191 0.2189
Onchocerca volvulus 0.0336 0.0131 0.0319
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1149 0.1117 0.1115
Echinococcus granulosus Vam6:Vps39 protein 0.1066 0.1015 0.1015
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0614 0.0468 0.0468
Loa Loa (eye worm) TK/INSR protein kinase 0.5434 0.6304 0.6303
Entamoeba histolytica tyrosin kinase, putative 0.0294 0.0081 0.0634
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1018 0.0958 0.9415
Echinococcus multilocularis tyrosine protein kinase csk 0.0294 0.0081 0.0081
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0356 0.0156 0.0155
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0424 0.0238 0.0238
Brugia malayi cytokine inducible SH2-containing protein 5 0.034 0.0137 0.0137
Echinococcus multilocularis N chimaerin 0.0527 0.0363 0.0363
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0107 0.0603
Onchocerca volvulus Netrin receptor homolog 0.0236 0.0011 0.0023
Echinococcus granulosus calcium activated potassium channel 0.0486 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.1213 0.1194 0.1193
Echinococcus multilocularis serine:threonine protein kinase N2 0.1396 0.1415 0.1415
Onchocerca volvulus 0.0336 0.0131 0.0319
Leishmania major protein kinase, putative 0.0867 0.0774 0.7905
Schistosoma mansoni protein kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.034 0.0136 0.0135
Brugia malayi Protein kinase domain containing protein 0.2357 0.2579 0.2579
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi P38 map kinase family protein 2 0.0567 0.0411 0.0411
Entamoeba histolytica PH domain containing protein kinase, putative 0.0589 0.0439 0.3477
Echinococcus multilocularis Immunoglobulin 0.0483 0.031 0.031
Schistosoma mansoni protein kinase 0.0294 0.0081 0.0081
Echinococcus granulosus roundabout 2 0.0839 0.0741 0.0741
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Protein kinase domain containing protein 0.1194 0.1171 0.1171
Echinococcus multilocularis protein kinase shaggy 0.0717 0.0594 0.0594
Schistosoma mansoni nephrin 0.0356 0.0156 0.0156
Entamoeba histolytica protein kinase, putative 0.1149 0.1117 0.8867
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.042 0.0234 0.1721
Brugia malayi Protein kinase domain containing protein 0.2036 0.2191 0.2191
Echinococcus granulosus suppressor of cytokine signaling 7 0.034 0.0137 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1283 0.1278 0.1278
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0567 0.0411 0.3865
Echinococcus multilocularis expressed conserved protein 0.0485 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.027 0.0052 0.0051
Echinococcus multilocularis tyrosine protein kinase otk 0.027 0.0052 0.0052
Schistosoma mansoni protein kinase 0.0818 0.0715 0.0715
Schistosoma mansoni growth factor receptor-bound protein 0.0562 0.0405 0.0405
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0567 0.0411 0.041
Schistosoma mansoni signal transduction protein lnk-related 0.034 0.0137 0.0137
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1684 0.1764 0.1764
Echinococcus granulosus hypothetical protein 0.034 0.0137 0.0137
Entamoeba histolytica PH domain containing protein kinase, putative 0.0669 0.0535 0.4242
Brugia malayi Protein kinase domain containing protein 0.0666 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Onchocerca volvulus 0.0294 0.0081 0.0196
Echinococcus granulosus protein tyrosine kinase 0.3565 0.4041 0.4041
Plasmodium vivax protein kinase, putative 0.0344 0.0142 0.0878
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1212 0.1192 0.1191
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0382 0.0188 0.0187
Echinococcus granulosus tyrosine protein kinase HCK 0.0836 0.0737 0.0737
Echinococcus granulosus signal transduction protein lnk realted 0.034 0.0137 0.0137
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0634 0.0493 0.3911
Giardia lamblia Kinase, CDC7 0.0336 0.0131 0.072
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.1018 0.0958 0.0958
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.034 0.0137 0.0333
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.034 0.0137 0.0137
Echinococcus granulosus contactin 0.0356 0.0156 0.0156
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0591 0.0441 0.4163
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica p21-activated kinase 0.0469 0.0293 0.2315
Loa Loa (eye worm) hypothetical protein 0.1066 0.1015 0.1014
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1781 0.1881 0.1881
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Loa Loa (eye worm) AUR protein kinase 0.0818 0.0715 0.0714
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1075 0.1027 0.1027
Schistosoma mansoni protein kinase 0.0424 0.0238 0.0238
Loa Loa (eye worm) RGC/RGC protein kinase 0.0311 0.0101 0.01
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis casein kinase I alpha 0.0399 0.0208 0.0208
Onchocerca volvulus 0.034 0.0137 0.0333
Plasmodium vivax serine/threonine protein kinase, putative 0.0313 0.0104 0.0336
Brugia malayi C1-like domain containing protein 0.1131 0.1095 0.1095
Loa Loa (eye worm) hypothetical protein 0.0872 0.0781 0.078
Echinococcus multilocularis roundabout 2 0.0356 0.0156 0.0156
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0434 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Echinococcus granulosus expressed conserved protein 0.034 0.0137 0.0137
Echinococcus multilocularis suppressor of cytokine signaling 6 0.034 0.0137 0.0137
Echinococcus granulosus N chimaerin 0.0527 0.0363 0.0363
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2379 0.2606 0.2605
Trichomonas vaginalis STE family protein kinase 0.0294 0.0081 0.0375
Echinococcus granulosus tyrosine protein kinase Blk 0.1176 0.1149 0.1149
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Echinococcus granulosus CDC7 cell division cycle 7 0.0336 0.0131 0.0131
Echinococcus granulosus rho-associated protein kinase 1 0.189 0.2014 0.2014
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Echinococcus multilocularis receptor type guanylyl cyclase 0.0311 0.0101 0.0101
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0356 0.0156 0.0156
Echinococcus granulosus SHC transforming protein 3 0.034 0.0137 0.0137
Trypanosoma cruzi aurora B kinase, putative 0.0818 0.0715 0.6952
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0624 0.0481 0.457
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.034 0.0137 0.0137
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0356 0.0156 0.0156
Echinococcus multilocularis titin 0.0372 0.0175 0.0175
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.027 0.0052 0.0051
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.044 0.0258 0.1709
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0308 0.0098 0.0097
Echinococcus granulosus tyrosine kinase 0.1176 0.1149 0.1149
Echinococcus granulosus casein kinase I gamma 0.0747 0.063 0.063
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0867 0.0774 0.755
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1212 0.1192 0.1191
Schistosoma mansoni serine/threonine protein kinase 0.0382 0.0188 0.0188
Echinococcus multilocularis hemicentin 1 0.027 0.0052 0.0052
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Onchocerca volvulus 0.0463 0.0285 0.0696
Echinococcus multilocularis suppressor of cytokine signaling 7 0.034 0.0137 0.0137
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0294 0.0081 0.0375
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1212 0.1192 0.1192
Echinococcus granulosus Glutaredoxin protein 5 0.0398 0.0208 0.0208
Echinococcus granulosus casein kinase I delta 0.0399 0.0208 0.0208
Brugia malayi Cam kinase protein 1 0.0372 0.0176 0.0176
Onchocerca volvulus 0.0252 0.0031 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus tyrosine protein kinase Srms 0.1993 0.2139 0.2139
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0545 0.0384 0.4376
Echinococcus multilocularis serine:threonine protein kinase 3 0.2072 0.2234 0.2234
Echinococcus granulosus casein kinase I alpha 0.0399 0.0208 0.0208
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0372 0.0176 0.0176
Trypanosoma cruzi protein kinase, putative 0.0294 0.0081 0.0513
Loa Loa (eye worm) TK protein kinase 0.0294 0.0081 0.008
Loa Loa (eye worm) AGC/NDR protein kinase 0.0751 0.0634 0.0633
Brugia malayi Immunoglobulin I-set domain containing protein 0.027 0.0052 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0188 0.1319
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Onchocerca volvulus 0.034 0.0137 0.0333
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0284 0.0069 0.0068
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0294 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0294 0.0081 0.0375
Entamoeba histolytica protein kinase domain containing protein 0.0717 0.0594 0.471
Echinococcus granulosus tyrosine protein kinase Fyn 0.139 0.1408 0.1408
Schistosoma mansoni serine/threonine protein kinase 0.0751 0.0634 0.0634
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0624 0.0481 0.3667
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0315 0.0107 0.0775
Giardia lamblia Kinase, CMGC GSK 0.0717 0.0594 0.7353
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0372 0.0176 0.0176
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Echinococcus multilocularis TGF beta receptor type 1 0.0525 0.036 0.036
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0235 0.001 0.0009
Loa Loa (eye worm) SH2 domain-containing protein 0.034 0.0137 0.0136
Echinococcus multilocularis activin receptor type 0.2373 0.2598 0.2598
Loa Loa (eye worm) hypothetical protein 0.2036 0.2191 0.2189
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0294 0.0081 0.008
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Trypanosoma cruzi polo-like protein kinase, putative 0.0831 0.0731 0.7116
Trichomonas vaginalis conserved hypothetical protein 0.0295 0.0083 0.0389
Loa Loa (eye worm) hypothetical protein 0.0231 0.0005 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1176 0.1149 0.1149
Giardia lamblia Kinase, CMGC CDK 0.0432 0.0249 0.2401
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) SH2 domain-containing protein 0.034 0.0137 0.0136
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Brugia malayi hypothetical protein 0.0244 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.156 0.1614 0.1614
Echinococcus multilocularis serine:threonine protein kinase 0.0417 0.023 0.023
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0313 0.0104 0.0214
Brugia malayi Kinase associated domain 1 family protein 0.034 0.0136 0.0136
Echinococcus multilocularis PAK box P21 Rho binding 0.0352 0.0151 0.0151
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis CDC7 cell division cycle 7 0.0336 0.0131 0.0131
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0751 0.0634 0.0634
Brugia malayi Peroxidasin 0.0272 0.0054 0.0054
Schistosoma mansoni suppressor of cytokine signaling 0.034 0.0137 0.0137
Echinococcus multilocularis natriuretic peptide receptor 1 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis 0.034 0.0137 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.1212 0.1192 0.1192
Schistosoma mansoni tyrosine kinase 0.5677 0.6599 0.6599
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0313 0.0104 0.075
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0432 0.0249 0.0247
Brugia malayi Protein kinase domain containing protein 0.2036 0.2191 0.2191
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0453 0.0274 0.0273
Plasmodium falciparum glycogen synthase kinase 3 0.0717 0.0594 0.7396
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.076 0.0645 0.0643
Echinococcus granulosus hypothetical protein 0.072 0.0597 0.0597
Schistosoma mansoni tyrosine kinase 0.0849 0.0753 0.0753
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0751 0.0634 0.0634
Echinococcus granulosus cyclin dependent kinase 19 0.0285 0.007 0.007
Echinococcus granulosus dual specificity 0.0382 0.0188 0.0188
Plasmodium falciparum serine/threonine protein kinase KIN 0.0453 0.0274 0.2782
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus granulosus mitogen activated protein kinase 0.0315 0.0107 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Giardia lamblia Kinase, CMGC CK2 0.037 0.0173 0.1319
Trypanosoma cruzi casein kinase, putative 0.0399 0.0208 0.1797
Plasmodium falciparum serine/threonine protein kinase 0.0313 0.0104 0.0336
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0545 0.0384 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0751 0.0634 0.0634
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.044 0.0258 0.231
Loa Loa (eye worm) hypothetical protein 0.0463 0.0285 0.0284
Entamoeba histolytica tyrosin kinase, putative 0.0294 0.0081 0.0634
Brugia malayi serine/threonine-protein kinase PAK 7 0.199 0.2135 0.2135
Echinococcus granulosus dual specificity 0.0382 0.0188 0.0188
Plasmodium vivax glycogen synthase kinase 3, putative 0.0717 0.0594 0.7396
Brugia malayi p70 ribosomal S6 kinase beta 0.1149 0.1117 0.1117
Trypanosoma cruzi casein kinase II, putative 0.037 0.0173 0.1447
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0432 0.0249 0.1909
Brugia malayi Fibronectin type III domain containing protein 0.0569 0.0414 0.0414
Brugia malayi protein kinase C3,putative 0.0609 0.0462 0.0462
Onchocerca volvulus 0.0244 0.002 0.0046
Entamoeba histolytica protein kinase, putative 0.1018 0.0958 0.7605
Echinococcus multilocularis protein kinase 0.0294 0.0081 0.0081
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0356 0.0156 0.0156
Trypanosoma brucei aurora B kinase 0.0818 0.0715 0.582
Brugia malayi Protein kinase domain containing protein 0.0613 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.072 0.0597 0.0596
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1781 0.1881 0.1881
Echinococcus multilocularis protein KINase family member (kin 25) 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0751 0.0634 0.0634
Brugia malayi SH2 domain containing protein 0.1646 0.1718 0.1718
Giardia lamblia Kinase, CMGC GSK 0.0717 0.0594 0.7353
Echinococcus multilocularis serine:threonine protein kinase N2 0.2147 0.2324 0.2324
Entamoeba histolytica protein kinase domain containing protein 0.0717 0.0594 0.471
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1176 0.1149 0.1149
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2573 0.284 0.284
Schistosoma mansoni tyrosine kinase 0.139 0.1408 0.1408
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi protein-tyrosine kinase 0.1176 0.1149 0.1149
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0294 0.0081 0.0081
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0591 0.0441 0.4163
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis SH2 domain containing adapter protein F 0.034 0.0137 0.0137
Entamoeba histolytica serine/threonine kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis casein kinase ii subunit alpha 0.037 0.0173 0.0173
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0398 0.0208 0.0208
Loa Loa (eye worm) TK/CSK protein kinase 0.0294 0.0081 0.008
Loa Loa (eye worm) protein-tyrosine phosphatase 0.034 0.0137 0.0136
Loa Loa (eye worm) hypothetical protein 0.0634 0.0493 0.0492
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Brugia malayi Immunoglobulin I-set domain containing protein 0.027 0.0052 0.0052
Loa Loa (eye worm) TK/FAK protein kinase 0.3604 0.4088 0.4087
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Loa Loa (eye worm) CAMK protein kinase 0.0372 0.0175 0.0174
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis protein kinase 0.0294 0.0081 0.0081
Onchocerca volvulus 0.103 0.0972 0.238
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0717 0.0594 0.5847
Entamoeba histolytica serine/threonine kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.034 0.0137 0.0137
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0382 0.0188 0.0981
Echinococcus granulosus serine:threonine protein kinase 0.0417 0.023 0.023
Trichomonas vaginalis TKL family protein kinase 0.0295 0.0083 0.0389
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0294 0.0081 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.007 0.007
Schistosoma mansoni tensin 0.034 0.0137 0.0137
Loa Loa (eye worm) protein kinase domain-containing protein 0.0294 0.0081 0.008
Echinococcus granulosus activated cdc42 kinase 1 0.0294 0.0081 0.0081
Brugia malayi map kinase activated protein kinase protein 2 0.135 0.136 0.136
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Echinococcus granulosus nervana 2 0.0398 0.0208 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis ephrin type A receptor 4 A 0.0507 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Brugia malayi cell division control protein 2 homolog 0.0432 0.0249 0.0249
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2379 0.2606 0.2606
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0294 0.0081 0.0375
Echinococcus granulosus nervana 2 0.0398 0.0208 0.0208
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0485 0.0312 0.2232
Schistosoma mansoni serine/threonine protein kinase 0.1018 0.0958 0.0958
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0624 0.0481 0.5765
Giardia lamblia Kinase, NEK 0.049 0.0319 0.3405
Schistosoma mansoni cell adhesion molecule 0.0356 0.0156 0.0156
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) TK protein kinase 0.192 0.205 0.2049
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) CDC7 protein kinase 0.0336 0.0131 0.013
Schistosoma mansoni ephrin receptor 0.038 0.0185 0.0185
Trypanosoma brucei cdc2-related kinase 3 0.0432 0.0249 0.1536
Loa Loa (eye worm) AGC/PKN protein kinase 0.2147 0.2324 0.2323
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0399 0.0208 0.1797
Echinococcus multilocularis protein tyrosine kinase 0.3565 0.4041 0.4041
Echinococcus multilocularis serine:threonine protein kinase 0.0417 0.023 0.023
Echinococcus granulosus tyrosine protein kinase csk 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Schistosoma mansoni kinase 0.0645 0.0507 0.0507
Echinococcus multilocularis casein kinase I delta 0.0399 0.0208 0.0208
Trypanosoma brucei protein kinase, putative 0.0717 0.0594 0.4705
Plasmodium falciparum cGMP-dependent protein kinase 0.0485 0.0312 0.3335
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.5572 0.6471 0.6471
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0424 0.0238 0.0238
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.111 0.1069 0.1068
Echinococcus granulosus tyrosine protein kinase Lyn 0.1537 0.1585 0.1585
Echinococcus multilocularis neuroglian 0.0356 0.0156 0.0156
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0672 0.0539 0.0538
Brugia malayi Immunoglobulin I-set domain containing protein 0.4072 0.4655 0.4655
Brugia malayi SRC-1 0.139 0.1408 0.1408
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1018 0.0958 0.0957
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Echinococcus granulosus SH2 motif 0.034 0.0137 0.0137
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0831 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0385 0.0191 0.019
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0294 0.0081 0.0375
Brugia malayi phosphoinositide-dependent protein kinase I 0.0308 0.0098 0.0098
Entamoeba histolytica serine/threonine protein kinase, putative 0.0831 0.0731 0.5805
Loa Loa (eye worm) RGC/RGC protein kinase 0.0311 0.0101 0.01
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Brugia malayi SH2 domain containing protein 0.0634 0.0493 0.0493
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0294 0.0081 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0624 0.0481 0.0481
Loa Loa (eye worm) TK/ACK protein kinase 0.0294 0.0081 0.008
Entamoeba histolytica hypothetical protein 0.1018 0.0958 0.7605
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.042 0.0234 0.0234
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0706 0.0579 0.0578
Giardia lamblia Kinase, STE STE20 0.0591 0.0441 0.5156
Onchocerca volvulus 0.0294 0.0081 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.023 0.1686
Loa Loa (eye worm) hypothetical protein 0.1352 0.1362 0.136
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus granulosus protein kinase C gamma type 0.0889 0.0801 0.0801
Echinococcus granulosus mitogen activated protein kinase 14 0.0567 0.0411 0.0411
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.3123 0.3506 0.3505
Brugia malayi Fes/CIP4 homology domain containing protein 0.1001 0.0937 0.0937
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0107 0.0603
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Protein kinase domain containing protein 0.0243 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0055 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.1283 0.1278 0.1278
Entamoeba histolytica casein kinase, putative 0.037 0.0173 0.1365
Brugia malayi Protein kinase domain containing protein 0.0634 0.0493 0.0493
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0583 0.0431 0.0431
Entamoeba histolytica protein kinase domain containing protein 0.037 0.0173 0.1365
Brugia malayi Protein kinase domain containing protein 0.1212 0.1192 0.1192
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0756 0.0641 0.0641
Echinococcus granulosus tensin 0.034 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.1066 0.1015 0.1014
Echinococcus granulosus dual specificity 0.0382 0.0188 0.0188
Brugia malayi cyclin-dependent kinase 7 homolog 0.0233 0.0007 0.0007
Schistosoma mansoni titin 0.0372 0.0175 0.0175
Giardia lamblia Kinase, CMGC CLK 0.0867 0.0774 0.9941
Schistosoma mansoni protein kinase 0.0615 0.0469 0.0469
Echinococcus multilocularis SH2 domain containing protein 7 0.034 0.0137 0.0137
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.076 0.0645 0.5353
Echinococcus granulosus protein kinase 0.1564 0.1619 0.1619
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus granulosus neuroglian 0.0356 0.0156 0.0156
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0624 0.0481 0.3667
Entamoeba histolytica ankyrin repeat protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0308 0.0098 0.0097
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0867 0.0774 0.6694
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0294 0.0081 0.0081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0569 0.0414 0.0414
Echinococcus multilocularis tyrosine protein kinase Fyn 0.139 0.1408 0.1408
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0244 0.002 0.0019
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Plasmodium vivax protein kinase Crk2 0.0432 0.0249 0.2415
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.3123 0.3506 0.3506
Loa Loa (eye worm) hypothetical protein 0.0614 0.0468 0.0467
Entamoeba histolytica receptor protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.1066 0.1015 0.1015
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0175 0.0175
Schistosoma mansoni roundabout 0.027 0.0052 0.0052
Onchocerca volvulus 0.0634 0.0493 0.1206
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0294 0.0081 0.0081
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0399 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.0244 0.002 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0819 0.0717 0.5989
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0372 0.0176 0.1369
Giardia lamblia Kinase, CK1 Casein kinase 0.0399 0.0208 0.1814
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0478 0.0304 0.0304
Brugia malayi Pleckstrin Homology Domain 0.0231 0.0005 0.0005
Echinococcus granulosus MAM 0.0244 0.002 0.002
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.5971 0.6955 0.6955
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0717 0.0594 0.5718
Echinococcus granulosus defective proboscis extension response 0.0483 0.031 0.031
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Echinococcus granulosus TGF beta receptor type 1 0.0525 0.036 0.036
Schistosoma mansoni serine/threonine protein kinase 0.135 0.136 0.136
Loa Loa (eye worm) hypothetical protein 0.103 0.0972 0.0971
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0818 0.0715 0.915
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.1066 0.1015 0.1015
Brugia malayi C-terminal src kinase protein 1 0.0294 0.0081 0.0081
Loa Loa (eye worm) TK/ABL protein kinase 0.2168 0.235 0.2349
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0296 0.0083 0.0648
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0272 0.0054 0.0054
Schistosoma mansoni septate junction protein 0.027 0.0052 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0624 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Giardia lamblia Kinase, CMGC MAPK 0.0315 0.0107 0.0371
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0294 0.0081 0.008
Loa Loa (eye worm) hypothetical protein 0.0307 0.0097 0.0096
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0453 0.0274 0.0274
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0567 0.0411 0.303
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0717 0.0594 0.0594
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.0312 0.0312
Schistosoma mansoni tyrosine kinase 0.3565 0.4041 0.4041
Echinococcus multilocularis mitogen activated protein kinase 14 0.0567 0.0411 0.0411
Brugia malayi Prion-like- 0.027 0.0052 0.0052
Schistosoma mansoni protein kinase 0.0679 0.0547 0.0547
Schistosoma mansoni hypothetical protein 0.0244 0.002 0.002
Entamoeba histolytica protein kinase, putative 0.0487 0.0314 0.2487
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0525 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.2063 0.2223 0.2222
Plasmodium vivax serine/threonine kinase-1, putative 0.0867 0.0774 1
Trichomonas vaginalis AGC family protein kinase 0.0818 0.0715 0.5977
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) hypothetical protein 0.0872 0.0781 0.078
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Schistosoma mansoni protein kinase 0.0424 0.0238 0.0238
Onchocerca volvulus Serine\/threonine kinase homolog 0.0583 0.0431 0.1054
Plasmodium falciparum serine/threonine protein kinase, putative 0.0818 0.0715 0.915
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0917 0.0836 0.0836
Trichomonas vaginalis AGC family protein kinase 0.0864 0.0771 0.6467
Schistosoma mansoni serine/threonine protein kinase 0.2147 0.2324 0.2324
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Entamoeba histolytica protein kinase, putative 0.0818 0.0715 0.5677
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0372 0.0176 0.0176
Echinococcus multilocularis mitogen activated protein kinase 11 0.0567 0.0411 0.0411
Trypanosoma cruzi casein kinase, putative 0.0399 0.0208 0.1797
Schistosoma mansoni serine/threonine protein kinase 0.0747 0.063 0.063
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Brugia malayi MAP kinase sur-1 0.0315 0.0107 0.0107
Echinococcus granulosus tyrosine protein kinase ABL1 0.2168 0.235 0.235
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0453 0.0274 0.2199
Schistosoma mansoni tyrosine kinase 0.2131 0.2305 0.2305
Schistosoma mansoni tyrosine kinase 0.1781 0.1881 0.1881
Echinococcus granulosus serine:threonine protein kinase mig 15 0.2484 0.2732 0.2732
Brugia malayi Tyrosine-protein kinase abl-1 0.0947 0.0872 0.0872
Entamoeba histolytica protein kinase, putative 0.0382 0.0188 0.1485
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Brugia malayi hypothetical protein 0.1066 0.1015 0.1015
Trichomonas vaginalis conserved hypothetical protein 0.0294 0.0081 0.0375
Brugia malayi Tensin 0.034 0.0137 0.0137
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.135 0.136 0.1359
Onchocerca volvulus 0.189 0.2014 0.4933
Brugia malayi Protein kinase domain containing protein 0.5572 0.6471 0.6471
Onchocerca volvulus 0.3164 0.3555 0.8713
Onchocerca volvulus 0.0634 0.0493 0.1206
Echinococcus multilocularis Glutaredoxin protein 5 0.0398 0.0208 0.0208
Schistosoma mansoni suppressor of cytokine signaling 0.034 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.1653 0.1727 0.1726
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Schistosoma mansoni serine/threonine protein kinase 0.0917 0.0836 0.0836
Brugia malayi STAT protein, DNA binding domain containing protein 0.034 0.0137 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Schistosoma mansoni protein kinase 0.1483 0.152 0.152
Brugia malayi Tyrosine-protein kinase abl-1 0.1435 0.1463 0.1463
Echinococcus granulosus Protein kinase C brain isozyme 0.1075 0.1027 0.1027
Entamoeba histolytica protein kinase, putative 0.0717 0.0594 0.471
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Schistosoma mansoni vesicular amine transporter 0.0483 0.031 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0274 0.0274
Plasmodium falciparum calcium-dependent protein kinase 1 0.0372 0.0176 0.1369
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0372 0.0176 0.0176
Schistosoma mansoni tyrosine kinase 0.8487 1 1
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0372 0.0176 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0298 0.0086 0.0415
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1066 0.1015 1
Leishmania major protein kinase, putative 0.0818 0.0715 0.7233
Giardia lamblia Kinase, AGC PKA 0.0545 0.0384 0.4351
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) thyroid receptor interactor 0.1001 0.0937 0.0936
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0434 0.025 0.025
Echinococcus granulosus tyrosine protein kinase Fyn 0.139 0.1408 0.1408
Echinococcus multilocularis casein kinase I gamma 0.0747 0.063 0.063
Loa Loa (eye worm) RGC/RGC protein kinase 0.0294 0.0081 0.008
Echinococcus multilocularis tyrosine protein kinase pr2 0.0294 0.0081 0.0081
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1018 0.0958 1
Loa Loa (eye worm) TK protein kinase 0.0294 0.0081 0.008
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Entamoeba histolytica serine/threonine protein kinase, putative 0.0453 0.0274 0.2167
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0527 0.0363 0.0363
Loa Loa (eye worm) AGC/PKA protein kinase 0.0624 0.0481 0.0479
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Entamoeba histolytica protein kinase, putative 0.0308 0.0098 0.0767
Echinococcus granulosus tyrosine protein kinase Fyn 0.139 0.1408 0.1408
Echinococcus granulosus Immunoglobulin 0.0483 0.031 0.031
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Schistosoma mansoni protein kinase 0.0399 0.0208 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0356 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Brugia malayi Temporarily assigned gene name protein 59 0.1066 0.1015 0.1015
Onchocerca volvulus 0.0363 0.0165 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0294 0.0081 0.0375
Echinococcus multilocularis expressed protein 0.0313 0.0104 0.0104
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0294 0.0081 0.0081
Onchocerca volvulus Tyrosine kinase homolog 0.3597 0.408 1
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Echinococcus multilocularis tyrosine protein kinase Fyn 0.139 0.1408 0.1408
Echinococcus granulosus myotubularin protein 13 0.0231 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0188 0.1319
Echinococcus granulosus serine/threonine protein kinase 0.0589 0.0439 0.0439
Schistosoma mansoni tensin 0.034 0.0137 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.135 0.136 0.136
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0624 0.0481 0.457
Schistosoma mansoni serine/threonine protein kinase 0.0756 0.0641 0.0641
Brugia malayi intracellular kinase 0.0717 0.0594 0.0594
Loa Loa (eye worm) AGC/AKT protein kinase 0.1194 0.1171 0.1169
Echinococcus granulosus c-Jun N-terminal kinases 0.0917 0.0836 0.0836
Entamoeba histolytica protein kinase, putative 0.0352 0.0151 0.1188
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0712 0.0587 0.0587
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Plasmodium falciparum protein kinase, putative 0.044 0.0258 0.2553
Entamoeba histolytica serine/threonine kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0398 0.0208 0.0208
Brugia malayi hypothetical protein 0.0323 0.0116 0.0116
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Protein kinase domain containing protein 0.0432 0.0249 0.0249
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Schistosoma mansoni tyrosine kinase 0.139 0.1408 0.1408
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1475 0.151 0.151
Echinococcus granulosus tyrosine kinase 0.0634 0.0493 0.0493
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1018 0.0958 0.9415
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1483 0.152 0.152
Brugia malayi bone morphogenetic protein type 1 receptor 0.0672 0.0539 0.0539
Schistosoma mansoni septate junction protein 0.027 0.0052 0.0052
Brugia malayi Immunoglobulin I-set domain containing protein 0.192 0.205 0.205
Schistosoma mansoni serine/threonine protein kinase 0.1626 0.1694 0.1694
Schistosoma mansoni growth factor receptor-bound protein 0.0555 0.0397 0.0397
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2573 0.284 0.284
Leishmania major casein kinase, putative 0.0399 0.0208 0.1442
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0818 0.0715 0.0715
Schistosoma mansoni titin 0.027 0.0052 0.0052
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0399 0.0208 0.0206
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0306 0.0096 0.0143
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Brugia malayi serine/threonine protein kinase 6 0.0818 0.0715 0.0715
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0818 0.0715 0.0715
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0188 0.1319
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus protein kinase shaggy 0.0717 0.0594 0.0594
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Schistosoma mansoni neuroglian 0.0356 0.0156 0.0156
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0399 0.0208 0.0206
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0294 0.0081 0.0634
Loa Loa (eye worm) hypothetical protein 0.0624 0.0481 0.0479
Echinococcus multilocularis neuroglian 0.0623 0.0479 0.0479
Echinococcus multilocularis peroxidasin 0.0272 0.0054 0.0054
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0679 0.0547 0.0546
Echinococcus multilocularis SH2 motif 0.034 0.0137 0.0137
Plasmodium vivax unspecified product 0.037 0.0173 0.1327
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Entamoeba histolytica hypothetical protein 0.0259 0.0039 0.0299
Loa Loa (eye worm) TK/RYK protein kinase 0.0294 0.0081 0.008
Echinococcus multilocularis myosin iiia 0.0591 0.0441 0.0441
Onchocerca volvulus 0.0294 0.0081 0.0196
Echinococcus granulosus TGF-beta receptor type-1 0.0525 0.036 0.036
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0372 0.0176 0.0176
Entamoeba histolytica protein kinase, putative 0.0296 0.0083 0.0648
Plasmodium vivax casein kinase 1, putative 0.0399 0.0208 0.1824
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.139 0.1408 0.1408
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0372 0.0175 0.0175
Brugia malayi tRNA modification GTPase TrmE family protein 0.034 0.0137 0.0137
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0372 0.0176 0.1369
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Echinococcus multilocularis dual specificity 0.0382 0.0188 0.0188
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0285 0.007 0.0068
Trypanosoma brucei casein kinase I, isoform 2 0.0399 0.0208 0.116
Trypanosoma brucei protein kinase, putative 0.044 0.0258 0.1624
Schistosoma mansoni protein kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0483 0.031 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Loa Loa (eye worm) hypothetical protein 0.0985 0.0918 0.0917
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis tyrosine protein kinase HCK 0.0836 0.0737 0.0737
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0917 0.0836 0.0834
Loa Loa (eye worm) hypothetical protein 0.0463 0.0285 0.0284
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0272 0.0055 0.0055
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.034 0.0137 0.0137
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Brugia malayi hypothetical protein 0.0634 0.0493 0.0493
Echinococcus granulosus twitchin 0.0769 0.0656 0.0656
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0313 0.0104 0.0225
Trypanosoma brucei polo-like protein kinase 0.0831 0.0731 0.5969
Plasmodium falciparum calcium-dependent protein kinase 3 0.0372 0.0176 0.1369
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0453 0.0274 0.2782
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0624 0.0481 0.3859
Onchocerca volvulus 0.0634 0.0493 0.1206
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0819 0.0717 0.0715
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0545 0.0384 0.3593
Onchocerca volvulus 0.0294 0.0081 0.0196
Schistosoma mansoni adapter molecule crk 0.0555 0.0397 0.0397
Entamoeba histolytica hypothetical protein 0.0296 0.0083 0.0648
Loa Loa (eye worm) TK/DDR protein kinase 0.0294 0.0081 0.008
Echinococcus multilocularis cyclin dependent kinase 1 0.0432 0.0249 0.0249
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1785 0.1886 0.1886
Loa Loa (eye worm) hypothetical protein 0.0799 0.0692 0.0691
Echinococcus multilocularis mitogen activated protein kinase 14 0.0567 0.0411 0.0411
Schistosoma mansoni protein kinase 0.0672 0.0539 0.0539
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0259 0.0039 0.0039
Giardia lamblia Kinase, STE STE20 0.0424 0.0238 0.2255
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.0714 0.059 0.059
Onchocerca volvulus 0.0634 0.0493 0.1206
Brugia malayi protein unc-22 0.0372 0.0175 0.0175
Echinococcus granulosus aurora kinase A 0.0818 0.0715 0.0715
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Brugia malayi Protein kinase domain containing protein 0.5434 0.6304 0.6304
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0583 0.0431 0.0431
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0527 0.0363 0.0363
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0567 0.0411 0.3865
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0272 0.0054 0.0054
Entamoeba histolytica serine/threonine kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus cGMP dependent protein kinase 0.0485 0.0312 0.0312
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0545 0.0384 0.0384
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Echinococcus granulosus SH2 motif 0.034 0.0137 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Entamoeba histolytica protein kinase, putative 0.0424 0.0238 0.1884
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Schistosoma mansoni serine/threonine-protein kinase 0.0589 0.0439 0.0439
Onchocerca volvulus 0.0634 0.0493 0.1206
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0233 0.0007 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.027 0.0052 0.0052
Echinococcus multilocularis protein kinase c iota type 0.1214 0.1195 0.1195
Loa Loa (eye worm) hypothetical protein 0.1066 0.1015 0.1014
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0453 0.0274 0.2199
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0372 0.0176 0.0916
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0818 0.0715 0.5677
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0382 0.0188 0.1033
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0372 0.0176 0.1369
Echinococcus granulosus casein kinase I delta 0.0399 0.0208 0.0208
Echinococcus multilocularis tyrosine protein kinase csk 0.0294 0.0081 0.0081
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0469 0.0293 0.0291
Echinococcus multilocularis calcium activated potassium channel 0.0486 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Entamoeba histolytica PH domain containing protein kinase, putative 0.0669 0.0535 0.4242
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.139 0.1408 0.1408
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.027 0.0052 0.0052
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Mycobacterium ulcerans hypothetical protein 0.0339 0.0135 0.5
Onchocerca volvulus 0.033 0.0124 0.0302
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.1066 0.1015 0.1015
Giardia lamblia Kinase, NEK 0.049 0.0319 0.3405
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Echinococcus multilocularis nervana 2 0.0398 0.0208 0.0208
Loa Loa (eye worm) TK/EGFR protein kinase 0.8487 1 1
Echinococcus multilocularis casein kinase i 0.0399 0.0208 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.027 0.0052 0.0052
Echinococcus granulosus casein kinase I alpha 0.0399 0.0208 0.0208
Trichomonas vaginalis STE family protein kinase 0.0424 0.0238 0.1763
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0717 0.0594 0.0592
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0432 0.0249 0.1909
Entamoeba histolytica protein kinase, putative 0.0396 0.0205 0.1619
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0849 0.0753 0.0753
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Trichomonas vaginalis protein tyrosine kinase, putative 0.0294 0.0081 0.0375
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Echinococcus granulosus suppressor of cytokine signaling 6 0.034 0.0137 0.0137
Entamoeba histolytica casein kinase 1, putative 0.0399 0.0208 0.164
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0751 0.0634 0.0634
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1684 0.1764 0.1764
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0624 0.0481 0.0481
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0589 0.0439 0.4143
Schistosoma mansoni tyrosine kinase 0.2472 0.2718 0.2718
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis rho associated protein kinase 0.189 0.2014 0.2014
Echinococcus multilocularis serine:threonine protein kinase N2 0.0831 0.0731 0.0731
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0629 0.0487 0.0486
Trichomonas vaginalis STE family protein kinase 0.0424 0.0238 0.1763
Trypanosoma brucei rac serine-threonine kinase, putative 0.1194 0.1171 1
Trichomonas vaginalis STE family protein kinase 0.0424 0.0238 0.1763
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.139 0.1408 0.1408
Brugia malayi Protein kinase domain containing protein 0.0469 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.1538 0.1587 0.1586
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0455 0.0276 0.0274
Leishmania major protein kinase A catalytic subunit isoform 1 0.0624 0.0481 0.4557
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0624 0.0481 0.5765
Entamoeba histolytica protein kinase 2, putative 0.0545 0.0384 0.3046
Brugia malayi RhoGAP domain containing protein 0.0527 0.0363 0.0363
Schistosoma mansoni protein kinase 0.044 0.0258 0.0258
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1342 0.135 0.1349
Brugia malayi Immunoglobulin I-set domain containing protein 0.027 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.034 0.0136 0.0136
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Brugia malayi hypothetical protein 0.2379 0.2606 0.2606
Echinococcus multilocularis mitogen activated protein kinase 0.0315 0.0107 0.0107
Brugia malayi casein kinase I 0.0399 0.0208 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Schistosoma mansoni tyrosine kinase 0.5677 0.6599 0.6599
Schistosoma mansoni serine/threonine protein kinase 0.189 0.2014 0.2014
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1131 0.1095 0.1094
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0301 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Schistosoma mansoni rap gtpase-activating protein 0.1066 0.1015 0.1015
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0455 0.0276 0.0276
Entamoeba histolytica protein kinase, putative 0.0272 0.0055 0.0426
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0424 0.0238 0.0238
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Leishmania major protein kinase, putative 0.044 0.0258 0.2019
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0188 0.1319
Loa Loa (eye worm) hypothetical protein 0.0319 0.0111 0.011
Brugia malayi Protein kinase domain containing protein 0.0634 0.0493 0.0493
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Echinococcus multilocularis serine:threonine protein kinase 38 0.0751 0.0634 0.0634
Echinococcus granulosus serine:threonine protein kinase 3 0.2072 0.2234 0.2234
Echinococcus multilocularis nervana 2 0.0398 0.0208 0.0208
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0336 0.0131 0.0131
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0382 0.0188 0.0188
Brugia malayi Protein kinase domain containing protein 0.0417 0.023 0.023
Schistosoma mansoni protein kinase 0.0615 0.0469 0.0469
Loa Loa (eye worm) hypothetical protein 0.0753 0.0637 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.1475 0.151 0.151
Brugia malayi Temporarily assigned gene name protein 59 0.043 0.0246 0.0246
Echinococcus granulosus insulin growth factor 1 receptor beta 0.552 0.6408 0.6408
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Loa Loa (eye worm) TK protein kinase 0.0294 0.0081 0.008
Brugia malayi Stress-activated protein kinase jnk-1 0.0917 0.0836 0.0836
Schistosoma mansoni nephrin 0.0709 0.0583 0.0583
Onchocerca volvulus 0.1744 0.1837 0.4499
Brugia malayi Guanylyl cyclase protein 23 0.0311 0.0101 0.0101
Toxoplasma gondii AGC kinase 0.0624 0.0481 0.3859
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0432 0.0249 0.1617
Schistosoma mansoni ephrin receptor 0.0507 0.034 0.034
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0107 0.0603
Echinococcus multilocularis tyrosine protein kinase Fgr 0.139 0.1408 0.1408
Trichomonas vaginalis protein kinase atn1, putative 0.0294 0.0081 0.0375
Echinococcus granulosus hemicentin 1 0.027 0.0052 0.0052
Echinococcus granulosus tyrosine protein kinase 0.2357 0.2579 0.2579
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Leishmania major protein kinase, putative 0.0591 0.0441 0.4101
Trypanosoma cruzi cdc2-related kinase 1 0.0432 0.0249 0.2213
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0615 0.0469 0.0469
Echinococcus granulosus fibroblast growth factor receptor 4 0.1781 0.1881 0.1881
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0313 0.0104 0.0103
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) TK protein kinase 0.0836 0.0737 0.0735
Echinococcus multilocularis dual specificity 0.0382 0.0188 0.0188
Giardia lamblia Kinase, CMGC DYRK 0.0382 0.0188 0.1533
Entamoeba histolytica protein kinase domain containing protein 0.0382 0.0188 0.1485
Schistosoma mansoni serine/threonine protein kinase 0.0756 0.0641 0.0641
Trichomonas vaginalis STE family protein kinase 0.0591 0.0441 0.355
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.1023 0.0964 0.0963
Echinococcus multilocularis epidermal growth factor receptor 0.5971 0.6955 0.6955
Schistosoma mansoni serine/threonine protein kinase 0.0624 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0294 0.0081 0.0375
Trypanosoma cruzi cdc2-related kinase 1 0.0432 0.0249 0.2213
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.139 0.1408 0.1408
Schistosoma mansoni hypothetical protein 0.1066 0.1015 0.1015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Trichomonas vaginalis STE family protein kinase 0.0424 0.0238 0.1763
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0061 0.02
Brugia malayi Immunoglobulin I-set domain containing protein 0.0356 0.0156 0.0156
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.552 0.6408 0.6408
Brugia malayi STE20-like kinase MST 0.2072 0.2234 0.2234
Brugia malayi Protein kinase domain containing protein 0.0583 0.0431 0.0431
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) TK/ROR protein kinase 0.0434 0.025 0.0249
Schistosoma mansoni serine/threonine protein kinase 0.0481 0.0307 0.0307
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Schistosoma mansoni protein kinase 0.0352 0.0151 0.0151
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1785 0.1886 0.1886
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.111 0.1069 0.1069
Brugia malayi hypothetical protein 0.0307 0.0097 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Schistosoma mansoni nck2/grb4 0.0555 0.0397 0.0397
Echinococcus granulosus activin receptor type 0.2373 0.2598 0.2598
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0372 0.0176 0.0176
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0107 0.0603
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Echinococcus multilocularis cyclin dependent kinase 7 0.0233 0.0007 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.2057 0.2215 0.2215
Trichomonas vaginalis AGC family protein kinase 0.0818 0.0715 0.5977
Echinococcus granulosus protein kinase c epsilon type 0.1023 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.027 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0717 0.0594 0.0592
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.156 0.1614 0.1614
Echinococcus multilocularis NCK adaptor protein 0.0562 0.0405 0.0405
Schistosoma mansoni serine/threonine protein kinase 0.0867 0.0774 0.0774
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.2072 0.2234 0.2233
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0356 0.0156 0.0156
Schistosoma mansoni tensin-related 0.034 0.0137 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0274 0.0274
Schistosoma mansoni protein kinase 0.0294 0.0081 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0286 0.0071 0.0071
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Schistosoma mansoni hypothetical protein 0.034 0.0137 0.0137
Brugia malayi probable protein kinase 0.263 0.2909 0.2909
Schistosoma mansoni serine/threonine protein kinase 0.0583 0.0431 0.0431
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0259 0.0039 0.0039
Onchocerca volvulus 0.0294 0.0081 0.0196
Schistosoma mansoni serine/threonine RGC 0.0294 0.0081 0.0081
Echinococcus granulosus cyclin dependent kinase 0.0432 0.0249 0.0249
Loa Loa (eye worm) TK protein kinase 0.0294 0.0081 0.008
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0294 0.0081 0.0081
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0539 0.0378 0.0376
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.034 0.0137 0.0136
Trichomonas vaginalis AGC family protein kinase 0.0818 0.0715 0.5977
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus casein kinase I alpha 0.0399 0.0208 0.0208
Brugia malayi Protein-tyrosine phosphatase containing protein 0.034 0.0137 0.0137
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1283 0.1278 0.1277
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Echinococcus granulosus titin 0.0372 0.0175 0.0175
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.027 0.0052 0.0052
Echinococcus granulosus casein kinase i 0.0399 0.0208 0.0208
Loa Loa (eye worm) AGC/PKA protein kinase 0.0624 0.0481 0.0479
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2379 0.2606 0.2606
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0274 0.0274
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0555 0.0397 0.0397
Brugia malayi Hr1 repeat family protein 0.2147 0.2324 0.2324
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Schistosoma mansoni protein kinase 0.263 0.2909 0.2909
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.034 0.0137 0.0137
Schistosoma mansoni protein kinase 0.1564 0.1619 0.1619
Trichomonas vaginalis AGC family protein kinase 0.0308 0.0098 0.0522
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0591 0.0441 0.3299
Trichomonas vaginalis AGC family protein kinase 0.0624 0.0481 0.3904
Schistosoma mansoni hypothetical protein 0.0372 0.0175 0.0175
Echinococcus multilocularis FL cytokine receptor 0.0294 0.0081 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) TK/Met protein kinase 0.0294 0.0081 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Brugia malayi Doublecortin family protein 0.0539 0.0378 0.0378
Onchocerca volvulus 0.0294 0.0081 0.0196
Brugia malayi hypothetical protein 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.049 0.0319 0.2292
Brugia malayi hypothetical protein 0.0294 0.0081 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.0313 0.0313
Toxoplasma gondii casein kinase I 0.0399 0.0208 0.1221
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0372 0.0176 0.0176
Trichomonas vaginalis CK1 family protein kinase 0.0399 0.0208 0.1492
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0308 0.0098 0.0098
Onchocerca volvulus 0.0666 0.0531 0.1298
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Leishmania major protein kinase, putative 0.0867 0.0774 0.7905
Echinococcus granulosus growth factor receptor bound protein 2 0.0562 0.0405 0.0405
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0301 0.0089 0.0089
Echinococcus granulosus cyclin dependent kinase 1 0.0432 0.0249 0.0249
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1475 0.151 0.1509
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0424 0.0238 0.0238
Loa Loa (eye worm) TK protein kinase 0.1305 0.1306 0.1304
Plasmodium falciparum protein serine/threonine kinase-1 0.0867 0.0774 1
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) hypothetical protein 0.027 0.0052 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Loa Loa (eye worm) SRC-1 0.139 0.1408 0.1407
Echinococcus granulosus tyrosine kinase 0.0311 0.0101 0.0101
Schistosoma mansoni protein kinase 0.0311 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0712 0.0587 0.0587
Entamoeba histolytica PH domain containing protein kinase, putative 0.0589 0.0439 0.3477
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0591 0.0441 0.3493
Entamoeba histolytica protein kinase, putative 0.0313 0.0104 0.082
Schistosoma mansoni cell adhesion molecule 0.027 0.0052 0.0052
Plasmodium falciparum calcium-dependent protein kinase 2 0.0372 0.0176 0.1369
Echinococcus granulosus NDR protein kinase 0.0751 0.0634 0.0634
Echinococcus multilocularis activated cdc42 kinase 1 0.0294 0.0081 0.0081
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0315 0.0107 0.025
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Schistosoma mansoni protein kinase 0.037 0.0173 0.0173
Entamoeba histolytica receptor protein kinase, putative 0.0294 0.0081 0.0634
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0294 0.0081 0.008
Trichomonas vaginalis AGC family protein kinase 0.0308 0.0098 0.0522
Onchocerca volvulus Basement membrane proteoglycan homolog 0.027 0.0052 0.0125
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.034 0.0137 0.0137
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0867 0.0774 0.755
Loa Loa (eye worm) hypothetical protein 0.0483 0.031 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.0432 0.0249 0.1853
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0624 0.0481 0.3667
Entamoeba histolytica protein kinase, putative 0.1194 0.1171 0.9298
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0567 0.0411 0.3765
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0717 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0712 0.0587 0.0586
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0624 0.0481 0.457
Echinococcus granulosus cyclin dependent kinase 5 0.0432 0.0249 0.0249
Entamoeba histolytica protein kinase domain containing protein 0.0818 0.0715 0.5677
Echinococcus granulosus kinase suppressor of Ras 1 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Echinococcus granulosus roundabout 2 0.0356 0.0156 0.0156
Schistosoma mansoni SH2A 0.034 0.0137 0.0137
Trichomonas vaginalis CK1 family protein kinase 0.0399 0.0208 0.1492
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.1564 0.1619 0.1618
Giardia lamblia Kinase, CMGC CDK 0.0432 0.0249 0.2401
Loa Loa (eye worm) TK/KIN16 protein kinase 0.4072 0.4655 0.4654
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0294 0.0081 0.0081
Echinococcus multilocularis tyrosine kinase 0.0311 0.0101 0.0101
Entamoeba histolytica protein kinase, putative 0.0272 0.0055 0.0426
Echinococcus multilocularis SH2 motif 0.034 0.0137 0.0137
Entamoeba histolytica hypothetical protein, conserved 0.0294 0.0081 0.0634
Schistosoma mansoni serine/threonine protein kinase 0.2379 0.2606 0.2606
Echinococcus granulosus tyrosine protein kinase otk 0.027 0.0052 0.0052
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis SH2 motif 0.034 0.0137 0.0137
Entamoeba histolytica SH2 domain containing protein 0.034 0.0137 0.108
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0555 0.0397 0.0396
Echinococcus multilocularis aurora kinase A 0.0818 0.0715 0.0715
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Brugia malayi Protein kinase domain containing protein 0.0679 0.0547 0.0547
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.139 0.1408 0.1408
Onchocerca volvulus 0.0985 0.0918 0.2247
Trichomonas vaginalis AGC family protein kinase 0.0818 0.0715 0.5977
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0315 0.0107 0.0106
Echinococcus multilocularis tensin 0.034 0.0137 0.0137
Entamoeba histolytica PH domain containing protein kinase, putative 0.0271 0.0053 0.0413
Echinococcus multilocularis tyrosine protein kinase Src64B 0.139 0.1408 0.1408
Trichomonas vaginalis CMGC family protein kinase 0.037 0.0173 0.1187
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0294 0.0081 0.0081
Loa Loa (eye worm) casein kinase 0.0601 0.0453 0.0451
Giardia lamblia Kinase, PLK 0.0831 0.0731 0.9328
Entamoeba histolytica cell division protein kinase 2, putative 0.0432 0.0249 0.1965
Schistosoma mansoni hypothetical protein 0.0294 0.0081 0.0081
Echinococcus granulosus peroxidasin 0.0272 0.0054 0.0054
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0315 0.0107 0.0775
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Schistosoma mansoni serine/threonine kinase 0.0751 0.0634 0.0634
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0188 0.1319
Brugia malayi Raf kinase 0.0294 0.0081 0.0081
Trichomonas vaginalis CMGC family protein kinase 0.0432 0.0249 0.1853
Loa Loa (eye worm) AUR protein kinase 0.0818 0.0715 0.0714
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0483 0.031 0.031
Echinococcus multilocularis epidermal growth factor receptor 0.8487 1 1
Brugia malayi Egg laying defective protein 4 0.0485 0.0312 0.0312
Onchocerca volvulus 0.034 0.0137 0.0333
Echinococcus multilocularis cyclin dependent kinase 5 0.0432 0.0249 0.0249
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Schistosoma mansoni tyrosine protein kinase 0.0294 0.0081 0.0081
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Echinococcus multilocularis c src tyrosine kinase 0.0849 0.0753 0.0753
Trypanosoma cruzi casein kinase, putative 0.0399 0.0208 0.1797
Echinococcus multilocularis hypothetical protein 0.034 0.0136 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0458 0.0279 0.2123
Echinococcus multilocularis Immunoglobulin 0.0483 0.031 0.031
Echinococcus granulosus c src tyrosine kinase 0.0849 0.0753 0.0753
Loa Loa (eye worm) hypothetical protein 0.0397 0.0205 0.0204
Schistosoma mansoni vav2 0.0572 0.0417 0.0417
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Giardia lamblia Kinase, AGC AKT 0.087 0.0778 1
Loa Loa (eye worm) TK/FER protein kinase 0.0634 0.0493 0.0492
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0372 0.0175 0.0174
Onchocerca volvulus 0.034 0.0137 0.0333
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus granulosus titin 0.0372 0.0175 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.0313 0.0313
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Loa Loa (eye worm) TK protein kinase 0.0294 0.0081 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0286 0.0072 0.007
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis tyrosine protein kinase Blk 0.1176 0.1149 0.1149
Echinococcus granulosus cyclin dependent kinase 7 0.0233 0.0007 0.0007
Schistosoma mansoni protein kinase 0.1483 0.152 0.152
Echinococcus multilocularis snurportin 1 0.0372 0.0175 0.0175
Echinococcus multilocularis signal transduction protein lnk realted 0.034 0.0137 0.0137
Entamoeba histolytica protein kinase, putative 0.0751 0.0634 0.5032
Echinococcus multilocularis 0.3511 0.3976 0.3976
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0372 0.0176 0.0916
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0176 0.1213
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0483 0.031 0.031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0356 0.0156 0.0156
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0294 0.0081 0.0081
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1475 0.151 0.151
Echinococcus multilocularis tyrosine protein kinase Srms 0.1176 0.1149 0.1149
Plasmodium falciparum calcium-dependent protein kinase 4 0.0372 0.0176 0.1369
Brugia malayi Receptor family ligand binding region containing protein 0.0311 0.0101 0.0101
Echinococcus multilocularis casein kinase I delta 0.0399 0.0208 0.0208
Schistosoma mansoni hypothetical protein 0.034 0.0136 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0176 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Brugia malayi Protein kinase domain containing protein 0.0747 0.063 0.063
Echinococcus granulosus SH2 domain containing protein 7 0.034 0.0137 0.0137
Giardia lamblia Kinase, CAMK CAMKL 0.0453 0.0274 0.2765
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1066 0.1015 0.8575
Giardia lamblia Kinase, CMGC SRPK 0.0313 0.0104 0.0334
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.156 0.1614 0.1614
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Echinococcus multilocularis cyclin dependent kinase 19 0.0285 0.007 0.007
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0756 0.0641 0.0641
Entamoeba histolytica protein kinase , putative 0.0818 0.0715 0.5677
Loa Loa (eye worm) SH2 domain-containing protein 0.034 0.0137 0.0136
Onchocerca volvulus 0.0799 0.0692 0.1694
Schistosoma mansoni protein kinase 0.0294 0.0081 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0712 0.0587 0.4655
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Echinococcus granulosus activated cdc42 kinase 1 0.0294 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.034 0.0137 0.0137
Brugia malayi Protein kinase domain containing protein 0.0308 0.0098 0.0098
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0294 0.0081 0.008
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Giardia lamblia Kinase, CAMK CAMKL 0.0453 0.0274 0.2765
Echinococcus multilocularis dual specificity 0.0382 0.0188 0.0188
Schistosoma mansoni tyrosine kinase 0.2365 0.2588 0.2588
Echinococcus multilocularis dual specificity protein kinase clk2 0.0867 0.0774 0.0774
Onchocerca volvulus 0.0372 0.0175 0.0426
Echinococcus multilocularis heat shock protein 70 0.0294 0.0081 0.0081
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0372 0.0176 0.0871
Loa Loa (eye worm) RGC/RGC protein kinase 0.0311 0.0101 0.01
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Trypanosoma cruzi protein kinase, putative 0.0294 0.0081 0.0513
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0294 0.0081 0.0081
Toxoplasma gondii AGC kinase 0.1149 0.1117 1
Trypanosoma brucei SNF1-related protein kinases, putative 0.0453 0.0274 0.177
Trichomonas vaginalis CMGC family protein kinase 0.0717 0.0594 0.4903
Entamoeba histolytica ankyrin repeat protein 0.0294 0.0081 0.0634
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Echinococcus granulosus receptor type guanylyl cyclase 0.0311 0.0101 0.0101
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.6157 0.7179 0.7179
Schistosoma mansoni tyrosine kinase 0.0564 0.0408 0.0408
Echinococcus multilocularis rac serine:threonine kinase 0.0589 0.0439 0.0439
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0294 0.0081 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.0274 0.0274
Brugia malayi ephrin receptor 1 precursor 0.0395 0.0203 0.0203
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1212 0.1192 0.1192
Brugia malayi Immunoglobulin I-set domain containing protein 0.027 0.0052 0.0052
Echinococcus multilocularis 0.1564 0.1619 0.1619
Echinococcus multilocularis raf serine:threonine protein kinase 0.0481 0.0307 0.0307
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.3123 0.3506 0.3506
Loa Loa (eye worm) hypothetical protein 0.088 0.0791 0.079
Echinococcus multilocularis integrin linked protein kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0649 0.0511 0.051
Schistosoma mansoni tyrosine kinase 0.5434 0.6304 0.6304
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1212 0.1192 0.2919
Echinococcus multilocularis tyrosine protein kinase 0.2357 0.2579 0.2579
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Brugia malayi Protein kinase domain containing protein 0.0455 0.0276 0.0276
Brugia malayi Protein kinase domain containing protein 0.1947 0.2083 0.2083
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0483 0.031 0.031
Brugia malayi serine/threonine-protein kinase plk-2 0.0831 0.0731 0.0731
Brugia malayi Variant SH3 domain containing protein 0.0391 0.0198 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.037 0.0173 0.1327
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0372 0.0176 0.0175
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.199 0.2135 0.2134
Loa Loa (eye worm) hypothetical protein 0.0417 0.023 0.0228
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1283 0.1278 0.1278
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0712 0.0587 0.0587
Trichomonas vaginalis TK family protein kinase 0.0295 0.0083 0.0389
Echinococcus granulosus mitogen activated protein kinase 3 0.0315 0.0107 0.0107
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0831 0.0731 0.7418
Brugia malayi Protein kinase domain 0.0424 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0272 0.0054 0.0053
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1212 0.1192 0.1192
Brugia malayi Tyrosine-protein kinase PR2 0.0294 0.0081 0.0081
Echinococcus multilocularis cyclin dependent kinase 1 0.0432 0.0249 0.0249
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0391 0.0198 0.0197
Echinococcus granulosus lachesin 0.027 0.0052 0.0052
Echinococcus granulosus casein kinase ii subunit alpha 0.037 0.0173 0.0173
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0867 0.0774 0.755
Echinococcus granulosus insulin receptor 0.5434 0.6304 0.6304
Loa Loa (eye worm) TK/FER protein kinase 0.1646 0.1718 0.1717
Schistosoma mansoni tyrosine kinase 0.0311 0.0101 0.0101
Schistosoma mansoni cell adhesion molecule 0.0356 0.0156 0.0156
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0382 0.0188 0.1219
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0867 0.0774 0.6361
Brugia malayi SH2 domain containing protein 0.034 0.0137 0.0137
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1646 0.1718 0.1718
Schistosoma mansoni serine/threonine protein kinase 0.0706 0.0579 0.0579
Schistosoma mansoni protein kinase C mu 0.1131 0.1095 0.1095
Entamoeba histolytica hypothetical protein 0.0297 0.0084 0.0659
Loa Loa (eye worm) serine/threonine protein kinase 0.0294 0.0081 0.008
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0453 0.0274 0.2471
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0294 0.0081 0.008
Entamoeba histolytica protein kinase domain containing protein 0.1018 0.0958 0.7605
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.027 0.0052 0.0051
Brugia malayi Protein kinase domain containing protein 0.0285 0.007 0.007
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0624 0.0481 0.457
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0294 0.0081 0.0081
Echinococcus granulosus tyrosine protein kinase Src42A 0.0888 0.0801 0.0801
Echinococcus multilocularis mitogen activated protein kinase 3 0.0315 0.0107 0.0107
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0356 0.0156 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0818 0.0715 0.0715
Loa Loa (eye worm) TK/EPH protein kinase 0.0566 0.041 0.0409
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0272 0.0055 0.0055
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0424 0.0238 0.0238
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0315 0.0107 0.0295
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.034 0.0137 0.0333
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0867 0.0774 0.0773
Onchocerca volvulus 0.0399 0.0208 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.156 0.1614 0.1614
Loa Loa (eye worm) hypothetical protein 0.0485 0.0312 0.031
Schistosoma mansoni tyrosine kinase 0.05 0.033 0.033
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0081 0.0081
Echinococcus granulosus tyrosine protein kinase csk 0.0294 0.0081 0.0081
Echinococcus granulosus tyrosine protein kinase Src64B 0.139 0.1408 0.1408
Loa Loa (eye worm) TK/ALK protein kinase 0.2329 0.2545 0.2544
Loa Loa (eye worm) hypothetical protein 0.0753 0.0637 0.0636
Brugia malayi casein kinase 1, delta 0.0399 0.0208 0.0208
Echinococcus multilocularis tyrosine protein kinase Abl 0.1435 0.1463 0.1463
Schistosoma mansoni tyrosine kinase 0.5971 0.6955 0.6955
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.1066 0.1015 0.1015
Echinococcus multilocularis cyclin dependent kinase 0.0432 0.0249 0.0249
Schistosoma mansoni serine/threonine-protein kinase 0.0589 0.0439 0.0439
Plasmodium falciparum casein kinase 2, alpha subunit 0.037 0.0173 0.1327
Trypanosoma cruzi cdc2-related kinase 3 0.0432 0.0249 0.2213
Echinococcus granulosus serine threonine protein kinase nrc 0.0545 0.0384 0.0384
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0294 0.0081 0.0081
Onchocerca volvulus Serine\/threonine kinase homolog 0.0831 0.0731 0.179
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Echinococcus multilocularis roundabout 2 0.0839 0.0741 0.0741
Brugia malayi Casein kinase II, alpha chain 0.037 0.0173 0.0173
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0294 0.0081 0.0081
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.049 0.0319 0.3425
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1283 0.1278 0.1278
Entamoeba histolytica protein kinase, putative 0.1194 0.1171 0.9298
Brugia malayi Protein kinase domain containing protein 0.0819 0.0717 0.0717
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1212 0.1192 0.1192
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.044 0.0258 0.1624
Echinococcus multilocularis dual specificity 0.1018 0.0958 0.0958
Onchocerca volvulus 0.1066 0.1015 0.2486
Schistosoma mansoni serine/threonine kinase 0.076 0.0645 0.0645
Schistosoma mansoni GTPase activating protein 0.034 0.0137 0.0137
Plasmodium falciparum NIMA related kinase 1 0.049 0.0319 0.3425
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Plasmodium falciparum casein kinase 1 0.0399 0.0208 0.1824
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) hypothetical protein 0.0453 0.0274 0.0273
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1018 0.0958 0.8046
Loa Loa (eye worm) protein kinase domain-containing protein 0.0747 0.063 0.0628
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0756 0.0641 0.0641
Brugia malayi Protein kinase domain containing protein 0.0634 0.0493 0.0493
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.027 0.0052 0.0051
Brugia malayi Serine/threonine-protein kinase SULU 0.2379 0.2606 0.2606
Echinococcus multilocularis roundabout 2 0.0356 0.0156 0.0156
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0294 0.0081 0.0081
Leishmania major protein kinase, putative 0.0372 0.0176 0.1082
Echinococcus granulosus serine:threonine kinase SAD 1 0.0453 0.0274 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0432 0.0249 0.0249
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis tyrosine protein kinase Fyn 0.139 0.1408 0.1408
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0831 0.0731 0.0731
Trichomonas vaginalis AGC family protein kinase 0.0751 0.0634 0.526
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0502 0.0333 0.0332
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0485 0.0312 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Schistosoma mansoni tyrosine kinase 0.5971 0.6955 0.6955
Brugia malayi hypothetical protein 0.034 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0569 0.0414 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.1075 0.1027 0.1027
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0294 0.0081 0.008
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0294 0.0081 0.0081
Onchocerca volvulus 0.034 0.0137 0.0333
Echinococcus multilocularis tyrosine kinase 0.0634 0.0493 0.0493
Trichomonas vaginalis CK1 family protein kinase 0.0399 0.0208 0.1492
Schistosoma mansoni protein kinase 0.1483 0.152 0.152
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1781 0.1881 0.1881
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0487 0.0314 0.2487
Plasmodium falciparum protein kinase 5 0.0432 0.0249 0.2415
Echinococcus multilocularis death associated protein kinase 1 0.2864 0.3193 0.3193
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.0399 0.0208 0.0208
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1066 0.1015 1
Loa Loa (eye worm) hypothetical protein 0.0463 0.0285 0.0284
Echinococcus multilocularis myotubularin protein 13 0.0231 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0294 0.0081 0.0634
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0915 0.0832 0.857
Entamoeba histolytica tyrosin kinase, putative 0.0294 0.0081 0.0634
Brugia malayi Sex muscle abnormal protein 5 0.0555 0.0397 0.0397
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0175 0.0174
Loa Loa (eye worm) hypothetical protein 0.0311 0.0101 0.01
Leishmania major casein kinase II, putative 0.037 0.0173 0.1049
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0527 0.0363 0.0362
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0673 0.054 0.4426
Brugia malayi protein C17H12.11 0.0323 0.0116 0.0116
Echinococcus granulosus neuroglian 0.0623 0.0479 0.0479
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0315 0.0107 0.0295
Brugia malayi Protein kinase domain containing protein 0.076 0.0645 0.0645
Schistosoma mansoni tyrosine-protein kinase zap-70 0.034 0.0137 0.0137
Echinococcus granulosus tensin C1 domain containing phosphatase 0.034 0.0137 0.0137
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0456 0.0277 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.1023 0.0964 0.0964
Loa Loa (eye worm) hypothetical protein 0.0569 0.0414 0.0413
Echinococcus granulosus protein kinase c iota type 0.1214 0.1195 0.1195
Echinococcus granulosus natriuretic peptide receptor 1 0.0294 0.0081 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0458 0.0279 0.2123
Onchocerca volvulus 0.0717 0.0594 0.1452
Loa Loa (eye worm) hypothetical protein 0.034 0.0137 0.0136
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0527 0.0363 0.0363
Echinococcus granulosus epidermal growth factor receptor 0.8487 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0867 0.0774 0.0774
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0624 0.0481 0.0481
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0188 0.1319
Trypanosoma brucei protein kinase, putative 0.0315 0.0107 0.0237
Brugia malayi serine/threonine kinase 12 0.0818 0.0715 0.0715
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0259 0.0039 0.0039
Leishmania major protein kinase A catalytic subunit 0.0624 0.0481 0.4557
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0478 0.0304 0.0304
Echinococcus multilocularis tyrosine protein kinase Src42A 0.139 0.1408 0.1408
Echinococcus granulosus fch and double sh3 domains protein 2 0.0228 0.0001 0.0001
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.027 0.0052 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0235 0.001 0.001
Trichomonas vaginalis AGC family protein kinase 0.0308 0.0098 0.0522
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0372 0.0176 0.0916
Echinococcus multilocularis casein kinase I alpha 0.0399 0.0208 0.0208
Schistosoma mansoni tensin-related 0.034 0.0137 0.0137
Echinococcus multilocularis transfer RNA-Thr 0.0294 0.0081 0.0081
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1483 0.152 0.152
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0469 0.0293 0.0291
Echinococcus granulosus NCK adaptor protein 0.0555 0.0397 0.0397
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0453 0.0274 0.2471
Schistosoma mansoni tyrosine kinase 0.5434 0.6304 0.6304
Loa Loa (eye worm) hypothetical protein 0.0307 0.0097 0.0096
Echinococcus multilocularis casein kinase I alpha 0.0399 0.0208 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.037 0.0173 0.0172
Entamoeba histolytica protein kinase, putative 0.0396 0.0205 0.1619
Brugia malayi serine/threonine-protein kinase 6 0.0818 0.0715 0.0715
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Leishmania major protein kinase A catalytic subunit isoform 2 0.0624 0.0481 0.4557
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0315 0.0107 0.0237
Loa Loa (eye worm) hypothetical protein 0.0294 0.0081 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Echinococcus granulosus expressed protein 0.0313 0.0104 0.0104
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0311 0.0101 0.0245
Schistosoma mansoni atypical protein kinase C 0.1234 0.1219 0.1219
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0591 0.0441 0.3493
Plasmodium vivax calcium-dependent protein kinase, putative 0.0372 0.0176 0.1369
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1212 0.1192 0.1192
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0432 0.0249 0.0249
Echinococcus multilocularis hemicentin 1 0.027 0.0052 0.0052
Schistosoma mansoni tyrosine kinase 0.0294 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0634 0.0493 0.0493
Trichomonas vaginalis conserved hypothetical protein 0.0294 0.0081 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.0831 0.0731 0.0731
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Schistosoma mansoni vam6/vps39 related 0.1066 0.1015 0.1015
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Brugia malayi Protein kinase domain containing protein 0.0313 0.0104 0.0104
Echinococcus multilocularis serine threonine protein kinase 0.0889 0.0801 0.0801
Trypanosoma brucei Casein kinase II 0.037 0.0173 0.0844
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0272 0.0055 0.0055
Schistosoma mansoni tyrosine kinase 0.5677 0.6599 0.6599
Trichomonas vaginalis STE family protein kinase 0.049 0.0319 0.2472
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0382 0.0188 0.1599
Trypanosoma cruzi cdc2-related kinase 3 0.0432 0.0249 0.2213
Echinococcus granulosus protein kinase 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus granulosus roundabout 2 0.0356 0.0156 0.0156
Echinococcus multilocularis insulin receptor 0.5434 0.6304 0.6304
Trichomonas vaginalis CAMK family protein kinase 0.0831 0.0731 0.612
Schistosoma mansoni serine/threonine protein kinase 0.1075 0.1027 0.1027
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0751 0.0634 0.0634
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.044 0.0258 0.231
Loa Loa (eye worm) hypothetical protein 0.027 0.0052 0.0051
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0756 0.0641 0.0641
Trypanosoma cruzi Protein kinase B 0.0589 0.0439 0.4143
Echinococcus granulosus tyrosine protein kinase Src42A 0.139 0.1408 0.1408
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis SHC transforming protein 3 0.034 0.0137 0.0137
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0272 0.0055 0.0055
Loa Loa (eye worm) AUR protein kinase 0.0818 0.0715 0.0714
Brugia malayi hypothetical protein 0.0569 0.0414 0.0414
Echinococcus multilocularis growth factor receptor bound protein 2 0.0555 0.0397 0.0397
Echinococcus multilocularis lachesin 0.027 0.0052 0.0052
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2168 0.235 0.235
Brugia malayi putative serine/threonine kinase SADA gamma 0.0453 0.0274 0.0274
Brugia malayi Variant SH3 domain containing protein 0.0555 0.0397 0.0397
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Brugia malayi Variant SH3 domain containing protein 0.0527 0.0363 0.0363
Brugia malayi Protein kinase domain containing protein 0.3123 0.3506 0.3506
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0417 0.023 0.0228
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Giardia lamblia Kinase, NEK 0.049 0.0319 0.3405
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trypanosoma brucei cdc2-related kinase 1 0.0432 0.0249 0.1536
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0131 0.0131
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0372 0.0176 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0717 0.0594 0.4903
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0818 0.0715 0.5677
Trichomonas vaginalis AGC family protein kinase 0.0819 0.0717 0.5989
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0712 0.0587 0.0587
Entamoeba histolytica protein kinase domain containing protein 0.0314 0.0106 0.083
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.0312 0.0312
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0313 0.0104 0.0266
Echinococcus multilocularis mitogen activated protein kinase 11 0.0567 0.0411 0.0411
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Toxoplasma gondii aurora kinase 0.0818 0.0715 0.6124
Entamoeba histolytica protein kinase, putative 0.0378 0.0183 0.1443
Loa Loa (eye worm) AGC/PKG protein kinase 0.0485 0.0312 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Plasmodium vivax tyrosine kinase-like protein, putative 0.0306 0.0096 0.0214
Schistosoma mansoni ste20-related kinase 0.1628 0.1696 0.1696
Trichomonas vaginalis STE family protein kinase 0.0352 0.0151 0.099
Trypanosoma cruzi casein kinase, putative 0.0399 0.0208 0.1797
Echinococcus granulosus mitogen activated protein kinase 11 0.0567 0.0411 0.0411
Trichomonas vaginalis CMGC family protein kinase 0.0336 0.0131 0.0818
Brugia malayi ribosomal protein S6 kinase alpha 3 0.087 0.0778 0.0778
Loa Loa (eye worm) STAT protein 0.034 0.0137 0.0136
Echinococcus granulosus tyrosine protein kinase shark 0.2472 0.2718 0.2718
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0424 0.0238 0.0238
Schistosoma mansoni shc transforming protein 0.034 0.0137 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0007 0.0007
Echinococcus multilocularis 0.072 0.0597 0.0597
Echinococcus granulosus dual specificity protein kinase clk2 0.0867 0.0774 0.0774
Entamoeba histolytica protein kinase, putative 0.1018 0.0958 0.7605
Onchocerca volvulus 0.0634 0.0493 0.1206
Entamoeba histolytica cell division protein kinase 2, putative 0.0432 0.0249 0.1965
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0453 0.0274 0.177
Onchocerca volvulus 0.0311 0.0101 0.0245
Loa Loa (eye worm) hypothetical protein 0.0244 0.002 0.0019
Echinococcus granulosus serine:threonine protein kinase 0.0417 0.023 0.023
Loa Loa (eye worm) TK protein kinase 0.1176 0.1149 0.1148
Entamoeba histolytica protein kinase domain containing protein 0.044 0.0258 0.2042
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0717 0.0594 0.0594
Echinococcus granulosus dual specificity 0.1018 0.0958 0.0958
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.0107 0.0107
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0545 0.0384 0.4376
Loa Loa (eye worm) hypothetical protein 0.0799 0.0692 0.0691
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0527 0.0363 0.0363
Brugia malayi Protein kinase domain containing protein 0.0294 0.0081 0.0081
Echinococcus multilocularis protein kinase c epsilon type 0.1023 0.0964 0.0964
Trichomonas vaginalis CAMK family protein kinase 0.042 0.0234 0.1721
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0081 0.0634
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0356 0.0156 0.0156
Brugia malayi Protein kinase domain containing protein 0.0729 0.0608 0.0608
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0555 0.0397 0.0396
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0306 0.0096 0.0214
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0818 0.0715 0.5677
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0867 0.0774 0.755
Entamoeba histolytica hypothetical protein 0.0296 0.0083 0.0648
Brugia malayi Protein kinase domain containing protein 0.0634 0.0493 0.0493
Trichomonas vaginalis CMGC family protein kinase 0.0336 0.0131 0.0818
Echinococcus granulosus cGMP dependent protein kinase 1 0.0485 0.0312 0.0312
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Loa Loa (eye worm) TK/FER protein kinase 0.0294 0.0081 0.008
Echinococcus granulosus SH2 domain containing adapter protein F 0.034 0.0137 0.0137
Echinococcus multilocularis tyrosine protein kinase csk 0.0294 0.0081 0.0081
Entamoeba histolytica protein kinase, putative 0.0836 0.0737 0.5847
Toxoplasma gondii AGC kinase 0.0624 0.0481 0.3859
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica tyrosin kinase, putative 0.0314 0.0106 0.083
Echinococcus granulosus retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Brugia malayi Protein kinase c protein 2 0.047 0.0295 0.0295
Brugia malayi integrin-linked kinase 0.0294 0.0081 0.0081
Schistosoma mansoni protein kinase 0.0525 0.036 0.036
Entamoeba histolytica protein kinase, putative 0.0313 0.0104 0.082
Trypanosoma cruzi polo-like protein kinase, putative 0.0831 0.0731 0.7116
Onchocerca volvulus 0.0294 0.0081 0.0196
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus granulosus MAP kinase activated protein kinase 2 0.135 0.136 0.136
Loa Loa (eye worm) hypothetical protein 0.0356 0.0156 0.0155
Trichomonas vaginalis AGC family protein kinase 0.1194 0.1171 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0294 0.0081 0.0081
Trypanosoma cruzi casein kinase, putative 0.0399 0.0208 0.1797
Entamoeba histolytica tyrosine kinase, putative 0.0294 0.0081 0.0634
Schistosoma mansoni protein kinase 0.0294 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0555 0.0397 0.0396
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0945 0.0869 0.0868
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0831 0.0731 0.073
Entamoeba histolytica protein kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis twitchin 0.0286 0.0071 0.0071
Echinococcus multilocularis suppressor of cytokine signaling 7 0.034 0.0137 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0432 0.0249 0.0249
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0295 0.0083 0.0389
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Echinococcus multilocularis tensin 0.034 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0323 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.0569 0.0414 0.0413
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0308 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0818 0.0715 0.5677
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.042 0.0234 0.0234
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0867 0.0774 0.6361
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Echinococcus multilocularis tyrosine protein kinase csk 0.0294 0.0081 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Trichomonas vaginalis AGC family protein kinase 0.049 0.0319 0.2472
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0583 0.0431 0.043
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0315 0.0107 0.0775
Schistosoma mansoni cell adhesion molecule 0.07 0.0572 0.0572
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0315 0.0107 0.0775
Brugia malayi Variant SH3 domain containing protein 0.0555 0.0397 0.0397
Schistosoma mansoni tyrosine kinase 0.0311 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0278 0.0061 0.006
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Entamoeba histolytica hypothetical protein 0.0296 0.0083 0.0648
Loa Loa (eye worm) hypothetical protein 0.1791 0.1894 0.1893
Brugia malayi Protein kinase domain containing protein 0.3604 0.4088 0.4088
Loa Loa (eye worm) hypothetical protein 0.2484 0.2732 0.2731
Schistosoma mansoni tensin 0.034 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.0244 0.002 0.002
Entamoeba histolytica casein kinase, putative 0.0399 0.0208 0.164
Echinococcus granulosus raf serine:threonine protein kinase 0.0481 0.0307 0.0307
Onchocerca volvulus 0.034 0.0137 0.0333
Trichomonas vaginalis TKL family protein kinase 0.0294 0.0081 0.0375
Giardia lamblia Kinase, AGC PKA 0.0624 0.0481 0.5731
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0888 0.0801 0.0801
Entamoeba histolytica serine/threonine kinase, putative 0.0294 0.0081 0.0634
Echinococcus multilocularis MAM 0.0244 0.002 0.002
Echinococcus granulosus tyrosine protein kinase pr2 0.0294 0.0081 0.0081
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0228 0.0001 0.0001
Onchocerca volvulus 0.0294 0.0081 0.0196
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0294 0.0081 0.0634
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1646 0.1718 0.1718
Trichomonas vaginalis CAMK family protein kinase 0.0453 0.0274 0.2078
Loa Loa (eye worm) IKK protein kinase 0.0666 0.0531 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0372 0.0176 0.1389
Trichomonas vaginalis CMGC family protein kinase 0.0867 0.0774 0.6497
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0432 0.0249 0.0247
Giardia lamblia Aurora kinase 0.0818 0.0715 0.9096

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.6626 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 141.2538 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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