Detailed information for compound 1366307

Basic information

Technical information
  • TDR Targets ID: 1366307
  • Name: methyl 4-[[1-[(1-acetyl-3,4-dihydro-2H-quinol in-6-yl)sulfonyl]piperidine-4-carbonyl]amino] benzoate
  • MW: 499.579 | Formula: C25H29N3O6S
  • H donors: 1 H acceptors: 5 LogP: 2 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccc2c(c1)CCCN2C(=O)C
  • InChi: 1S/C25H29N3O6S/c1-17(29)28-13-3-4-20-16-22(9-10-23(20)28)35(32,33)27-14-11-18(12-15-27)24(30)26-21-7-5-19(6-8-21)25(31)34-2/h5-10,16,18H,3-4,11-15H2,1-2H3,(H,26,30)
  • InChiKey: WPRJZIGDAXSBLL-UHFFFAOYSA-N  

Network

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Synonyms

  • 4-[[[1-[(1-acetyl-3,4-dihydro-2H-quinolin-6-yl)sulfonyl]-4-piperidinyl]-oxomethyl]amino]benzoic acid methyl ester
  • 4-[[1-[(1-acetyl-3,4-dihydro-2H-quinolin-6-yl)sulfonyl]piperidine-4-carbonyl]amino]benzoic acid methyl ester
  • methyl 4-[[1-[(1-ethanoyl-3,4-dihydro-2H-quinolin-6-yl)sulfonyl]piperidin-4-yl]carbonylamino]benzoate
  • G855-0612
  • NCGC00135291-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lamin A/C Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0851 0.0626 0.5243
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0702 0.0475 0.0475
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0268 0.0032 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.051 0.0279 0.032
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0607 0.0378 0.0996
Plasmodium falciparum serine/threonine protein kinase 0.0246 0.001 0.0075
Brugia malayi SH2 domain containing protein 0.0836 0.0611 0.0702
Echinococcus multilocularis roundabout 2 0.0347 0.0113 0.0113
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0832 0.0607 0.0606
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0702 0.0475 0.1257
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0268 0.0032 0.003
Echinococcus multilocularis titin 0.0436 0.0203 0.0203
Plasmodium falciparum protein kinase, putative 0.0268 0.0032 0.028
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Plasmodium falciparum protein kinase 5 0.0521 0.0291 0.2682
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3246 0.3065 0.3065
Brugia malayi putative serine/threonine kinase SADA gamma 0.0402 0.0169 0.0193
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Giardia lamblia Kinase, CMGC CDK 0.0521 0.0291 0.237
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0402 0.0169 0.0191
Echinococcus multilocularis dual specificity protein kinase clk2 0.1186 0.0968 0.0967
Schistosoma mansoni serine/threonine protein kinase 0.0436 0.0203 0.0525
Echinococcus granulosus tyrosine protein kinase shark 0.0737 0.051 0.0585
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.1051 0.083 0.0953
Trichomonas vaginalis STE family protein kinase 0.0421 0.0189 0.1566
Trichomonas vaginalis protein tyrosine kinase, putative 0.0268 0.0032 0.0253
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Schistosoma mansoni tyrosine kinase 0.0475 0.0243 0.0632
Schistosoma mansoni protein kinase 0.2563 0.237 0.6369
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0952 0.0729 0.0838
Echinococcus granulosus N chimaerin 0.0404 0.0171 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0305 0.007 0.0571
Echinococcus granulosus dual specificity 0.0308 0.0074 0.0084
Brugia malayi cyclin-dependent kinase 7 homolog 0.0745 0.0518 0.0595
Brugia malayi Fes/CIP4 homology domain containing protein 0.0899 0.0675 0.0775
Loa Loa (eye worm) hypothetical protein 0.1049 0.0828 0.0951
Trypanosoma cruzi casein kinase, putative 0.0689 0.0462 0.0528
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0354 0.012 0.0136
Brugia malayi Protein kinase domain containing protein 0.05 0.0269 0.0308
Schistosoma mansoni vav2 0.0451 0.0219 0.0568
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1574 0.1363 0.1363
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0268 0.0032 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0074 0.0085
Entamoeba histolytica serine/threonine protein kinase, putative 0.0402 0.0169 0.144
Plasmodium vivax calcium-dependent protein kinase, putative 0.0607 0.0378 0.3492
Trypanosoma brucei Pseudokinase, putative 0.0268 0.0032 0.0035
Echinococcus granulosus cyclin dependent kinase 9 0.0441 0.0208 0.0239
Onchocerca volvulus 0.0268 0.0032 0.003
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1132 0.0912 0.0912
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0268 0.0032 0.0032
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0691 0.0463 0.399
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0268 0.0032 0.003
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0851 0.0626 0.0717
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.012 0.0992
Loa Loa (eye worm) hypothetical protein 0.0631 0.0403 0.0462
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1192 0.0973 0.1118
Entamoeba histolytica protein kinase, putative 0.0421 0.0189 0.1615
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0247 0.0011 0.001
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0851 0.0626 0.5805
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Toxoplasma gondii protein kinase 0.0268 0.0032 0.028
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1294 0.1077 0.1238
Onchocerca volvulus Slit protein homolog 0.0303 0.0068 0.0077
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0244 0.0008 0.0053
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.082 0.0594 0.0683
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0591 0.0362 0.0361
Plasmodium falciparum calcium-dependent protein kinase 4 0.0607 0.0378 0.3492
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2422 0.2226 0.2557
Trichomonas vaginalis CAMK family protein kinase 0.0464 0.0232 0.193
Loa Loa (eye worm) hypothetical protein 0.0607 0.0378 0.0434
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni rap gtpase-activating protein 0.0762 0.0535 0.142
Echinococcus multilocularis serine:threonine protein kinase 3 0.0439 0.0207 0.0206
Echinococcus granulosus protein kinase c epsilon type 0.0788 0.0562 0.0645
Schistosoma mansoni serine/threonine protein kinase 0.0614 0.0385 0.1016
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1372 0.1157 0.1326
Loa Loa (eye worm) TK protein kinase 0.0268 0.0032 0.0037
Entamoeba histolytica receptor protein kinase, putative 0.0268 0.0032 0.0261
Echinococcus multilocularis tyrosine protein kinase csk 0.0268 0.0032 0.0032
Entamoeba histolytica tyrosin kinase, putative 0.0319 0.0085 0.0716
Toxoplasma gondii AGC kinase 0.0851 0.0626 0.5805
Loa Loa (eye worm) TK/FAK protein kinase 0.3928 0.376 0.4319
Schistosoma mansoni tyrosine kinase 0.1132 0.0912 0.2438
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Schistosoma mansoni tyrosine kinase 0.0962 0.074 0.1972
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0345 0.0111 0.0128
Loa Loa (eye worm) projectin 0.0245 0.0009 0.001
Echinococcus multilocularis mitogen activated protein kinase 11 0.8784 0.8705 0.8705
Echinococcus multilocularis NCK adaptor protein 0.043 0.0197 0.0197
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0521 0.0291 0.0334
Entamoeba histolytica PH domain containing protein kinase, putative 0.0375 0.0142 0.121
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0607 0.0378 0.0434
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Echinococcus granulosus nephrin 0.0245 0.0009 0.001
Loa Loa (eye worm) TK protein kinase 0.0268 0.0032 0.0037
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0268 0.0032 0.0037
Echinococcus multilocularis cyclin dependent kinase 19 0.1769 0.1561 0.1561
Schistosoma mansoni tyrosine kinase 0.3885 0.3716 1
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2661 0.247 0.2837
Echinococcus multilocularis hemicentin 1 0.0309 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Loa Loa (eye worm) hypothetical protein 0.0402 0.0169 0.0194
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0271 0.0036 0.0291
Schistosoma mansoni tyrosine kinase 0.0694 0.0467 0.1236
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Loa Loa (eye worm) TK protein kinase 0.0952 0.0729 0.0838
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0247 0.0011 0.001
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0268 0.0032 0.0037
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0268 0.0032 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0521 0.0291 0.2422
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0614 0.0385 0.0385
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Loa Loa (eye worm) hypothetical protein 0.0829 0.0604 0.0694
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0404 0.0171 0.017
Echinococcus multilocularis calcium dependent protein kinase 0.0416 0.0184 0.0183
Loa Loa (eye worm) hypothetical protein 0.0829 0.0604 0.0694
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1574 0.1363 0.1565
Brugia malayi protein kinase C3,putative 0.0454 0.0222 0.0255
Echinococcus granulosus contactin 0.0347 0.0113 0.0129
Schistosoma mansoni protein kinase 0.0691 0.0463 0.1225
Schistosoma mansoni tyrosine kinase 0.0899 0.0675 0.1798
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.001 0.0005
Loa Loa (eye worm) TK/Met protein kinase 0.0268 0.0032 0.0037
Echinococcus multilocularis casein kinase I alpha 0.0689 0.0462 0.0461
Echinococcus granulosus epidermal growth factor receptor 0.0962 0.074 0.0849
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0862 0.0637 0.0732
Entamoeba histolytica casein kinase, putative 0.0689 0.0462 0.398
Echinococcus multilocularis tyrosine protein kinase pr2 0.0268 0.0032 0.0032
Brugia malayi Guanylyl cyclase protein 23 0.0268 0.0032 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase, putative 0.0691 0.0463 0.399
Trypanosoma brucei Flagellum attachment zone protein 20 0.0268 0.0032 0.0035
Echinococcus granulosus tyrosine protein kinase csk 0.0268 0.0032 0.0037
Schistosoma mansoni serine/threonine kinase 0.0508 0.0277 0.0723
Loa Loa (eye worm) TK/CSK protein kinase 0.0268 0.0032 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0308 0.0074 0.0084
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0247 0.0011 0.0082
Loa Loa (eye worm) hypothetical protein 0.1095 0.0875 0.1005
Echinococcus multilocularis N chimaerin 0.0404 0.0171 0.017
Entamoeba histolytica serine/threonine kinase, putative 0.0268 0.0032 0.0261
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0268 0.0032 0.0253
Echinococcus multilocularis peroxidasin 0.0312 0.0077 0.0077
Toxoplasma gondii AGC kinase 0.0752 0.0525 0.4863
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0591 0.0362 0.0415
Echinococcus multilocularis rho associated protein kinase 0.083 0.0605 0.0605
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0952 0.0729 0.0729
Schistosoma mansoni tyrosine kinase 0.0577 0.0347 0.0912
Brugia malayi Protein kinase domain containing protein 0.0799 0.0574 0.0659
Loa Loa (eye worm) RGC/RGC protein kinase 0.0268 0.0032 0.0037
Trypanosoma brucei cdc2-related kinase 3 0.0521 0.0291 0.0331
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0286 0.0051 0.005
Schistosoma mansoni protein kinase 0.0421 0.0189 0.0486
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0459 0.0227 0.026
Schistosoma mansoni protein kinase 0.0459 0.0227 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus receptor type guanylyl cyclase 0.0268 0.0032 0.0037
Schistosoma mansoni kinase 0.0441 0.0208 0.0539
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0282 0.0047 0.0053
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Plasmodium falciparum calcium-dependent protein kinase 1 0.0607 0.0378 0.3492
Loa Loa (eye worm) hypothetical protein 0.0996 0.0774 0.0889
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0591 0.0362 0.0416
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0009 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0851 0.0626 0.1667
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0268 0.0032 0.0253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0009 0.001
Plasmodium vivax glycogen synthase kinase 3, putative 0.1294 0.1077 1
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0315 0.008 0.008
Echinococcus multilocularis tyrosine kinase 0.0268 0.0032 0.0032
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1186 0.0968 0.1109
Entamoeba histolytica tyrosin kinase, putative 0.0268 0.0032 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.05 0.0269 0.0309
Trypanosoma cruzi cdc2-related kinase 1 0.0521 0.0291 0.0331
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0268 0.0032 0.028
Leishmania major protein kinase A catalytic subunit isoform 2 0.0851 0.0626 0.0717
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Giardia lamblia Kinase, CMGC CDK 0.0521 0.0291 0.237
Trichomonas vaginalis CMGC family protein kinase 0.1294 0.1077 0.903
Giardia lamblia Kinase, AGC PKA 0.0851 0.0626 0.521
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1186 0.0968 0.1109
Brugia malayi Tyrosine-protein kinase abl-1 0.1265 0.1048 0.1204
Echinococcus multilocularis raf serine:threonine protein kinase 0.044 0.0207 0.0207
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0614 0.0385 0.0442
Brugia malayi Variant SH3 domain containing protein 0.0412 0.0179 0.0205
Echinococcus granulosus beta-adrenergic receptor kinase 0.0345 0.0111 0.0128
Schistosoma mansoni kinase 0.0424 0.0191 0.0493
Schistosoma mansoni serine/threonine protein kinase 0.0555 0.0325 0.0852
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0719
Giardia lamblia Kinase, CMGC MAPK 0.0247 0.0011 0.0006
Brugia malayi Protein kinase domain containing protein 0.0862 0.0637 0.0732
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Schistosoma mansoni hypothetical protein 0.0344 0.011 0.0273
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Echinococcus granulosus dual specificity mitogen activated protein 0.1407 0.1193 0.137
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1132 0.0912 0.0912
Echinococcus granulosus mitogen activated protein kinase 11 0.8784 0.8705 1
Echinococcus multilocularis casein kinase I gamma 0.0391 0.0157 0.0157
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1539 0.1326 0.1524
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0899 0.0675 0.0775
Brugia malayi Protein kinase domain containing protein 0.05 0.0269 0.0308
Echinococcus granulosus cyclin dependent kinase 5 0.0521 0.0291 0.0334
Entamoeba histolytica cysteine surface protein, putative 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1372 0.1157 0.1326
Echinococcus multilocularis protein kinase c epsilon type 0.0788 0.0562 0.0561
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2442 0.2247 0.2581
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0762 0.0535 0.142
Echinococcus granulosus cyclin dependent kinase 0.0521 0.0291 0.0334
Brugia malayi hypothetical protein 0.05 0.0269 0.0308
Toxoplasma gondii AGC kinase 0.0851 0.0626 0.5805
Echinococcus granulosus mitogen activated protein kinase 14 0.8784 0.8705 1
Schistosoma mansoni protein kinase 0.0421 0.0189 0.0486
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Entamoeba histolytica protein kinase domain containing protein 0.1372 0.1157 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0719
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0441 0.0208 0.0239
Brugia malayi bone morphogenetic protein type 1 receptor 0.1055 0.0834 0.0957
Onchocerca volvulus 0.0762 0.0535 0.0683
Brugia malayi protein kinase C II. 0.0788 0.0562 0.0645
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0691 0.0463 0.399
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2563 0.237 0.2722
Brugia malayi Peroxidasin 0.0312 0.0077 0.0089
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0354 0.012 0.0138
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0459 0.0227 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Loa Loa (eye worm) CAMK/PKD protein kinase 0.102 0.0798 0.0917
Schistosoma mansoni tyrosine kinase 0.1116 0.0896 0.2394
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0521 0.0291 0.0334
Echinococcus granulosus dual specificity 0.0308 0.0074 0.0084
Trichomonas vaginalis STE family protein kinase 0.0305 0.007 0.0571
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Echinococcus granulosus mitogen activated protein kinase 3 0.0247 0.0011 0.0012
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0268 0.0032 0.0032
Echinococcus granulosus tyrosine protein kinase Blk 0.0952 0.0729 0.0838
Echinococcus granulosus lachesin 0.0309 0.0074 0.0085
Schistosoma mansoni tyrosine kinase 0.1574 0.1363 0.3653
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0701 0.0473 0.0544
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1141 0.0922 0.1059
Echinococcus granulosus retinal guanylyl cyclase 2 0.0268 0.0032 0.0037
Echinococcus granulosus fibroblast growth factor receptor 4 0.1574 0.1363 0.1565
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0328 0.0093 0.0107
Entamoeba histolytica PH domain containing protein kinase, putative 0.0375 0.0142 0.121
Schistosoma mansoni serine/threonine-protein kinase 0.0375 0.0142 0.036
Loa Loa (eye worm) hypothetical protein 0.0344 0.011 0.0126
Schistosoma mansoni nephrin 0.0947 0.0724 0.193
Echinococcus multilocularis activin receptor type 0.4477 0.4319 0.4318
Echinococcus granulosus serine:threonine protein kinase N2 0.129 0.1074 0.1233
Entamoeba histolytica ankyrin repeat protein 0.0268 0.0032 0.0261
Brugia malayi Sex muscle abnormal protein 5 0.0412 0.0179 0.0205
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0328 0.0093 0.0848
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0836 0.0611 0.0611
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0607 0.0378 0.0434
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0412 0.0179 0.0205
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Brugia malayi Variant SH3 domain containing protein 0.0281 0.0046 0.0052
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0962 0.074 0.0849
Brugia malayi integrin-linked kinase 0.0268 0.0032 0.0037
Schistosoma mansoni hemicentin 0.0245 0.0009 0.0001
Echinococcus granulosus casein kinase I alpha 0.0689 0.0462 0.053
Entamoeba histolytica ankyrin repeat protein 0.0268 0.0032 0.0261
Trichomonas vaginalis STE family protein kinase 0.0248 0.0012 0.0083
Entamoeba histolytica protein kinase, putative 0.0445 0.0213 0.1823
Brugia malayi Protein kinase domain containing protein 0.0464 0.0232 0.0266
Plasmodium falciparum casein kinase 2, alpha subunit 0.0265 0.003 0.0254
Echinococcus granulosus roundabout 2 0.1049 0.0828 0.0951
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Echinococcus granulosus casein kinase I alpha 0.0689 0.0462 0.053
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Entamoeba histolytica protein kinase, putative 0.1372 0.1157 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0268 0.0032 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.012 0.0992
Onchocerca volvulus 0.037 0.0137 0.0166
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0626
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Trypanosoma cruzi cdc2-related kinase 3 0.0521 0.0291 0.0331
Echinococcus granulosus cGMP dependent protein kinase 1 0.0303 0.0069 0.0078
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.8784 0.8705 1
Echinococcus multilocularis neuroglian 0.0909 0.0685 0.0685
Schistosoma mansoni tyrosine kinase 0.0679 0.0452 0.1195
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1115 0.0895 0.1028
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0607 0.0378 0.0431
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1294 0.1077 0.1238
Onchocerca volvulus 0.05 0.0269 0.0337
Loa Loa (eye worm) hypothetical protein 0.0702 0.0475 0.0545
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0336 0.0102 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.0143 0.0363
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0268 0.0032 0.0032
Schistosoma mansoni cell adhesion molecule 0.0842 0.0617 0.1642
Plasmodium falciparum casein kinase 1 0.0689 0.0462 0.4274
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Echinococcus multilocularis PAK box P21 Rho binding 0.0397 0.0164 0.0164
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Brugia malayi map kinase activated protein kinase protein 2 0.0591 0.0362 0.0415
Entamoeba histolytica p21-activated kinase 0.0469 0.0237 0.2036
Loa Loa (eye worm) hypothetical protein 0.4654 0.4499 0.5168
Echinococcus multilocularis twitchin 0.0397 0.0164 0.0164
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0308 0.0074 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0011 0.0074
Echinococcus multilocularis tyrosine protein kinase Abl 0.1463 0.1249 0.1249
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0268 0.0032 0.0032
Echinococcus multilocularis tyrosine kinase 0.05 0.0269 0.0268
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1186 0.0968 0.1109
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.289 0.2703 0.3105
Trichomonas vaginalis CAMK family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1583 0.1372 0.1575
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0521 0.0291 0.0334
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0436 0.0203 0.0233
Leishmania major casein kinase, putative 0.0689 0.0462 0.0528
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0402 0.0169 0.0168
Echinococcus granulosus insulin receptor 0.1521 0.1309 0.1503
Loa Loa (eye worm) hypothetical protein 0.0309 0.0074 0.0085
Plasmodium falciparum calcium-dependent protein kinase 3 0.0607 0.0378 0.3492
Schistosoma mansoni tyrosine kinase 0.1132 0.0912 0.2438
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.003 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0683 0.0455 0.1205
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica hypothetical protein 0.0271 0.0036 0.0291
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0268 0.0032 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0308 0.0074 0.0662
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0074 0.0598
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0499 0.0268 0.0305
Echinococcus multilocularis beta adrenergic receptor kinase 0.0345 0.0111 0.0111
Trypanosoma cruzi cdc2-related kinase 1 0.0521 0.0291 0.0331
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Leishmania major protein kinase, putative 0.0691 0.0463 0.0529
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0679 0.0452 0.1195
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0347 0.0113 0.0113
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1132 0.0912 0.1048
Onchocerca volvulus 0.05 0.0269 0.0337
Echinococcus multilocularis TGF beta receptor type 1 0.0977 0.0755 0.0755
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0607 0.0378 0.0434
Echinococcus multilocularis natriuretic peptide receptor 1 0.0268 0.0032 0.0032
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Trichomonas vaginalis STE family protein kinase 0.0421 0.0189 0.1566
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0811 0.0586 0.0673
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0247 0.0011 0.001
Toxoplasma gondii hypothetical protein 0.05 0.0269 0.248
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.8784 0.8705 1
Loa Loa (eye worm) hypothetical protein 0.028 0.0044 0.0051
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0514 0.0283 0.0283
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Brugia malayi Variant SH3 domain containing protein 0.0412 0.0179 0.0205
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Brugia malayi C-terminal src kinase protein 1 0.0268 0.0032 0.0037
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0762 0.0535 0.0612
Loa Loa (eye worm) hypothetical protein 0.0373 0.0139 0.016
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Trichomonas vaginalis AGC family protein kinase 0.0658 0.043 0.3593
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0851 0.0626 0.0717
Giardia lamblia Kinase, STE STE20 0.0421 0.0189 0.1508
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0245 0.0009 0.001
Brugia malayi Casein kinase II, alpha chain 0.0265 0.003 0.0034
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0246 0.001 0.0009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0009 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Echinococcus granulosus neuroglian 0.0347 0.0113 0.0129
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0281 0.0046 0.0052
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni nephrin 0.0347 0.0113 0.0282
Echinococcus multilocularis cyclin dependent kinase 0.0521 0.0291 0.029
Schistosoma mansoni atypical protein kinase C 0.0885 0.0661 0.1759
Brugia malayi Protein kinase domain containing protein 0.0377 0.0143 0.0164
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0614 0.0385 0.0385
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0247 0.0011 0.001
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0952 0.0729 0.0838
Echinococcus multilocularis aurora kinase A 0.0691 0.0463 0.0463
Echinococcus granulosus protein kinase c iota type 0.0878 0.0654 0.0751
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.0169 0.0431
Brugia malayi ephrin receptor 1 precursor 0.0301 0.0066 0.0076
Onchocerca volvulus 0.05 0.0269 0.0337
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.083 0.0605 0.1609
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0321 0.0087 0.01
Loa Loa (eye worm) hypothetical protein 0.0309 0.0074 0.0085
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.0165 0.1368
Trichomonas vaginalis STE family protein kinase 0.0421 0.0189 0.1566
Schistosoma mansoni serine/threonine protein kinase 0.1539 0.1326 0.3554
Brugia malayi Cam kinase protein 1 0.0607 0.0378 0.0434
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0702 0.0475 0.0545
Echinococcus granulosus casein kinase I delta 0.0689 0.0462 0.053
Schistosoma mansoni protein kinase 0.0265 0.003 0.0057
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0702 0.0475 0.0475
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0421 0.0189 0.0216
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0421 0.0189 0.0188
Toxoplasma gondii casein kinase I 0.0689 0.0462 0.4274
Leishmania major protein kinase, putative 0.1186 0.0968 0.1109
Echinococcus multilocularis 0.0254 0.0019 0.0018
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Echinococcus multilocularis tyrosine protein kinase Blk 0.0952 0.0729 0.0729
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0074 0.0598
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Plasmodium vivax tyrosine kinase-like protein, putative 0.0244 0.0008 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0047 0.0372
Entamoeba histolytica hypothetical protein 0.1372 0.1157 1
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0336 0.0102 0.0117
Trypanosoma brucei rac serine-threonine kinase, putative 0.0799 0.0574 0.0656
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni tyrosine kinase 0.0694 0.0467 0.1236
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1372 0.1157 0.1329
Brugia malayi Protein kinase domain containing protein 0.082 0.0594 0.0682
Onchocerca volvulus 0.1001 0.0779 0.1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3901 0.3732 0.4287
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0268 0.0032 0.0064
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0305 0.007 0.0633
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0009 0.001
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2563 0.237 0.237
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0305 0.007 0.0633
Onchocerca volvulus 0.03 0.0065 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.0362 0.0953
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0009 0.0053
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1539 0.1326 0.1523
Plasmodium falciparum protein serine/threonine kinase-1 0.1186 0.0968 0.898
Echinococcus granulosus serine:threonine protein kinase TAO1 0.289 0.2703 0.3105
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Echinococcus multilocularis epidermal growth factor receptor 0.0962 0.074 0.0739
Echinococcus multilocularis mitogen activated protein kinase 0.0247 0.0011 0.0011
Echinococcus granulosus aurora kinase A 0.0691 0.0463 0.0531
Echinococcus granulosus activin receptor type 0.4477 0.4319 0.4961
Schistosoma mansoni vesicular amine transporter 0.0702 0.0475 0.1257
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0268 0.0032 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0614 0.0385 0.3218
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0607 0.0378 0.0434
Brugia malayi P38 map kinase family protein 2 0.8784 0.8705 1
Leishmania major protein kinase, putative 0.0459 0.0227 0.0258
Giardia lamblia Kinase, CAMK CAMKL 0.0445 0.0213 0.1715
Trypanosoma cruzi Protein kinase B 0.0375 0.0142 0.016
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1178 0.0959 0.1101
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0475 0.0243 0.0279
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.012 0.0302
Schistosoma mansoni serine/threonine RGC 0.0268 0.0032 0.0064
Echinococcus multilocularis integrin linked protein kinase 0.0268 0.0032 0.0032
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0268 0.0032 0.0037
Giardia lamblia Kinase, CMGC GSK 0.1294 0.1077 0.9024
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0473 0.1254
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0268 0.0032 0.0037
Brugia malayi Receptor family ligand binding region containing protein 0.0268 0.0032 0.0037
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0851 0.0626 0.0717
Schistosoma mansoni adapter molecule crk 0.0412 0.0179 0.0459
Echinococcus multilocularis transfer RNA-Phe 0.0245 0.0009 0.0009
Echinococcus granulosus MAM 0.0344 0.011 0.0126
Echinococcus multilocularis cyclin dependent kinase 5 0.0521 0.0291 0.029
Schistosoma mansoni serine/threonine protein kinase 0.1899 0.1694 0.4546
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0347 0.0113 0.013
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0402 0.0169 0.0191
Trypanosoma cruzi casein kinase II, putative 0.0265 0.003 0.0031
Onchocerca volvulus 0.0499 0.0268 0.0336
Brugia malayi probable protein kinase 0.1813 0.1606 0.1844
Leishmania major protein kinase A catalytic subunit 0.0851 0.0626 0.0717
Brugia malayi Protein kinase domain containing protein 0.05 0.0269 0.0308
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0851 0.0626 0.0719
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0375 0.0142 0.016
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0268 0.0032 0.0037
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1186 0.0968 0.1109
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2478 0.2284 0.2283
Onchocerca volvulus 0.0354 0.012 0.0145
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0445 0.0213 0.1961
Loa Loa (eye worm) hypothetical protein 0.0762 0.0535 0.0615
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1407 0.1193 0.1368
Loa Loa (eye worm) hypothetical protein 0.1181 0.0962 0.1106
Trypanosoma cruzi polo-like protein kinase, putative 0.0354 0.012 0.0136
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Brugia malayi Protein kinase domain containing protein 0.0391 0.0157 0.018
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0308 0.0074 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0288 0.0053 0.0428
Schistosoma mansoni vam6/vps39 related 0.0762 0.0535 0.142
Echinococcus granulosus c-Jun N-terminal kinases 0.3246 0.3065 0.352
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.012 0.0992
Echinococcus granulosus roundabout 2 0.0347 0.0113 0.0129
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Loa Loa (eye worm) hypothetical protein 0.0331 0.0097 0.0111
Loa Loa (eye worm) hypothetical protein 0.1181 0.0962 0.1106
Loa Loa (eye worm) TK/INSR protein kinase 0.1521 0.1309 0.1504
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0347 0.0113 0.0113
Loa Loa (eye worm) TK/EPH protein kinase 0.0358 0.0125 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.2478 0.2284 0.6136
Entamoeba histolytica PH domain containing protein kinase, putative 0.0899 0.0675 0.5828
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0111 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0011 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0702 0.0475 0.0474
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0308 0.0074 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0032 0.0064
Leishmania major protein kinase, putative 0.0248 0.0012 0.0011
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0459 0.0227 0.2086
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0689 0.0462 0.053
Schistosoma mansoni cell adhesion molecule 0.0245 0.0009 0.0001
Echinococcus granulosus cGMP dependent protein kinase 0.0303 0.0069 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0788 0.0562 0.1492
Echinococcus granulosus Protein kinase C brain isozyme 0.0832 0.0607 0.0696
Loa Loa (eye worm) hypothetical protein 0.0303 0.0068 0.0078
Entamoeba histolytica protein kinase, putative 0.0799 0.0574 0.4949
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0074 0.0598
Schistosoma mansoni protein kinase 0.0459 0.0227 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0268 0.0032 0.0253
Brugia malayi Protein kinase domain containing protein 0.1186 0.0968 0.1111
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1132 0.0912 0.1048
Loa Loa (eye worm) hypothetical protein 0.1538 0.1325 0.1523
Plasmodium vivax tyrosine kinase-like protein, putative 0.0268 0.0032 0.028
Trichomonas vaginalis CAMK family protein kinase 0.0373 0.0139 0.1148
Echinococcus granulosus calcium activated potassium channel 0.0373 0.0139 0.016
Brugia malayi Protein kinase domain containing protein 0.0614 0.0385 0.0442
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Echinococcus granulosus twitchin 0.1099 0.0879 0.101
Echinococcus multilocularis mitogen activated protein kinase 14 0.8784 0.8705 0.8705
Trichomonas vaginalis CK1 family protein kinase 0.0689 0.0462 0.3859
Loa Loa (eye worm) hypothetical protein 0.164 0.143 0.1642
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Plasmodium vivax tyrosine kinase-like protein, putative 0.0268 0.0032 0.028
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0851 0.0626 0.5805
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0368 0.0134 0.0154
Entamoeba histolytica protein kinase, putative 0.1372 0.1157 1
Echinococcus multilocularis tyrosine protein kinase 0.0268 0.0032 0.0032
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2478 0.2284 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Brugia malayi Protein kinase domain containing protein 0.0652 0.0423 0.0486
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0424 0.0191 0.1587
Loa Loa (eye worm) hypothetical protein 0.0671 0.0443 0.0509
Entamoeba histolytica hypothetical protein 0.0422 0.0189 0.1616
Schistosoma mansoni serine/threonine protein kinase 0.0521 0.0291 0.0761
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0268 0.0032 0.0037
Schistosoma mansoni hypothetical protein 0.0268 0.0032 0.0064
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0607 0.0378 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0851 0.0626 0.1667
Brugia malayi Protein kinase domain containing protein 0.2478 0.2284 0.2623
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0111 0.0277
Trichomonas vaginalis AGC family protein kinase 0.0691 0.0463 0.3869
Loa Loa (eye worm) hypothetical protein 0.05 0.0269 0.0308
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0248 0.0012 0.0085
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1738 0.1529 0.1756
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0074 0.0085
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1141 0.0922 0.0922
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1956 0.1752 0.2012
Trichomonas vaginalis AGC family protein kinase 0.0614 0.0385 0.3218
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus titin 0.0436 0.0203 0.0233
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Loa Loa (eye worm) TK protein kinase 0.0268 0.0032 0.0037
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1372 0.1157 0.1326
Echinococcus granulosus growth factor receptor bound protein 2 0.043 0.0197 0.0226
Giardia lamblia Protein 21.1 0.0268 0.0032 0.0186
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1132 0.0912 0.0912
Brugia malayi RhoGAP domain containing protein 0.0404 0.0171 0.0196
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0245 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.5267 0.5124 0.5886
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0328 0.0093 0.0105
Echinococcus granulosus serine:threonine protein kinase 3 0.0439 0.0207 0.0237
Echinococcus multilocularis calcium activated potassium channel 0.0373 0.0139 0.0139
Entamoeba histolytica protein kinase , putative 0.0691 0.0463 0.399
Entamoeba histolytica protein kinase, putative 0.0445 0.0213 0.1823
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Echinococcus granulosus Vam6:Vps39 protein 0.0762 0.0535 0.0615
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1956 0.1752 0.2013
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0379 0.0145 0.0167
Echinococcus granulosus protein kinase 0.0268 0.0032 0.0037
Echinococcus multilocularis slit 2 protein 0.0303 0.0068 0.0068
Loa Loa (eye worm) SRC-1 0.1132 0.0912 0.1048
Echinococcus granulosus cyclin dependent kinase 9 0.0485 0.0253 0.029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0009 0.001
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0412 0.0179 0.0205
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0246 0.001 0.0009
Loa Loa (eye worm) TK protein kinase 0.1781 0.1573 0.1807
Echinococcus multilocularis mitogen activated protein kinase 11 0.8784 0.8705 0.8705
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1141 0.0922 0.1059
Schistosoma mansoni protein kinase 0.2563 0.237 0.6369
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Brugia malayi hypothetical protein 0.0268 0.0032 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Trichomonas vaginalis TK family protein kinase 0.0268 0.0032 0.0253
Echinococcus multilocularis 0.0996 0.0774 0.0773
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0473 0.1254
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1583 0.1372 0.1575
Schistosoma mansoni protein tyrosine kinase 0.0268 0.0032 0.0064
Giardia lamblia Kinase, CK1 Casein kinase 0.0689 0.0462 0.3817
Echinococcus multilocularis casein kinase ii subunit alpha 0.0265 0.003 0.0029
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0788 0.0562 0.0645
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1407 0.1193 0.1368
Schistosoma mansoni growth factor receptor-bound protein 0.0412 0.0179 0.0459
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.6073 0.5944 0.6829
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Trichomonas vaginalis TKL family protein kinase 0.027 0.0035 0.0275
Echinococcus multilocularis rac serine:threonine kinase 0.0375 0.0142 0.0142
Trypanosoma brucei SNF1-related protein kinases, putative 0.0402 0.0169 0.0191
Echinococcus multilocularis c src tyrosine kinase 0.0679 0.0452 0.0451
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0952 0.0729 0.0729
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0303 0.0069 0.0616
Plasmodium falciparum calcium-dependent protein kinase 2 0.0607 0.0378 0.3492
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0421 0.0189 0.0216
Echinococcus granulosus kinase suppressor of Ras 1 0.0268 0.0032 0.0037
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1407 0.1193 0.1368
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0404 0.0171 0.0196
Entamoeba histolytica protein kinase domain containing protein 0.1294 0.1077 0.9314
Echinococcus granulosus tyrosine kinase 0.0268 0.0032 0.0037
Echinococcus granulosus tyrosine kinase 0.0952 0.0729 0.0838
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Loa Loa (eye worm) RGC/RGC protein kinase 0.0268 0.0032 0.0037
Echinococcus multilocularis roundabout 2 0.0347 0.0113 0.0113
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Schistosoma mansoni protein kinase 0.0397 0.0164 0.042
Schistosoma mansoni serine/threonine protein kinase 0.0691 0.0463 0.1225
Entamoeba histolytica protein kinase, putative 0.0246 0.001 0.007
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0555 0.0325 0.0324
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0268 0.0032 0.0037
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Entamoeba histolytica cell division protein kinase 2, putative 0.0521 0.0291 0.2498
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis cyclin dependent kinase 1 0.0521 0.0291 0.029
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0246 0.001 0.0075
Entamoeba histolytica serine/threonine kinase, putative 0.0268 0.0032 0.0261
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0691 0.0463 0.0463
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0268 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0344 0.011 0.0126
Echinococcus multilocularis myosin iiia 0.0248 0.0012 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Echinococcus multilocularis Immunoglobulin 0.0702 0.0475 0.0474
Entamoeba histolytica protein kinase, putative 0.0614 0.0385 0.3319
Loa Loa (eye worm) hypothetical protein 0.0631 0.0403 0.0462
Toxoplasma gondii protein kinase domain-containing protein 0.0268 0.0032 0.028
Echinococcus granulosus roundabout 2 0.0347 0.0113 0.0129
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0762 0.0535 0.142
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0011 0.0074
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1186 0.0968 0.898
Echinococcus granulosus dual specificity 0.1372 0.1157 0.1328
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Loa Loa (eye worm) RGC/RGC protein kinase 0.0268 0.0032 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) AUR protein kinase 0.0691 0.0463 0.0532
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0309 0.0074 0.0084
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0614 0.0385 0.0443
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.289 0.2703 0.2703
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0009 0.001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0421 0.0189 0.0216
Brugia malayi Protein kinase domain containing protein 0.1908 0.1702 0.1955
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Plasmodium falciparum protein kinase, putative 0.0459 0.0227 0.2086
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0328 0.0093 0.0093
Echinococcus granulosus dual specificity 0.0308 0.0074 0.0084
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0009 0.001
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0459 0.0227 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) hypothetical protein 0.1908 0.1702 0.1956
Brugia malayi Protein kinase domain containing protein 0.082 0.0594 0.0682
Giardia lamblia Kinase, AGC AKT 0.1115 0.0895 0.7479
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Echinococcus granulosus tyrosine protein kinase Src42A 0.0702 0.0475 0.0545
Brugia malayi Protein kinase domain containing protein 0.1521 0.1309 0.1503
Trichomonas vaginalis CAMK family protein kinase 0.0607 0.0378 0.3154
Echinococcus granulosus neuroglian 0.0909 0.0685 0.0787
Onchocerca volvulus 0.0268 0.0032 0.003
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0286 0.0051 0.0058
Echinococcus granulosus insulin growth factor 1 receptor beta 0.156 0.1348 0.1548
Onchocerca volvulus 0.2829 0.2641 0.3418
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0654 0.0426 0.1126
Brugia malayi Immunoglobulin I-set domain containing protein 0.0347 0.0113 0.0129
Echinococcus multilocularis casein kinase I delta 0.0689 0.0462 0.0461
Schistosoma mansoni cell adhesion molecule 0.0347 0.0113 0.0282
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Echinococcus multilocularis casein kinase I alpha 0.0689 0.0462 0.0461
Loa Loa (eye worm) TK protein kinase 0.0604 0.0375 0.0431
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0459 0.0227 0.0258
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2548 0.2355 0.2354
Trichomonas vaginalis AGC family protein kinase 0.0691 0.0463 0.3869
Schistosoma mansoni tyrosine kinase 0.2316 0.2119 0.5691
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.082 0.0594 0.0683
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Giardia lamblia Kinase, CMGC GSK 0.1294 0.1077 0.9024
Echinococcus granulosus hemicentin 1 0.0309 0.0074 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.0208 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus casein kinase ii subunit alpha 0.0265 0.003 0.0034
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0555 0.0325 0.0324
Trichomonas vaginalis AGC family protein kinase 0.0691 0.0463 0.3869
Brugia malayi EGF-like domain containing protein 0.0303 0.0068 0.0078
Schistosoma mansoni neuroglian 0.0347 0.0113 0.0282
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Trypanosoma brucei protein kinase, putative 0.1294 0.1077 0.1235
Echinococcus granulosus natriuretic peptide receptor 1 0.0268 0.0032 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Onchocerca volvulus 0.0268 0.0032 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.012 0.0992
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Brugia malayi Protein kinase domain containing protein 0.0614 0.0385 0.0442
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0246 0.001 0.0012
Brugia malayi Protein kinase domain containing protein 0.0521 0.0291 0.0334
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0344 0.011 0.0126
Brugia malayi cyclin-dependent kinase 9 0.0441 0.0208 0.0239
Echinococcus multilocularis casein kinase I delta 0.0689 0.0462 0.0461
Echinococcus granulosus c src tyrosine kinase 0.0679 0.0452 0.0518
Brugia malayi Protein kinase domain containing protein 0.0244 0.0009 0.0009
Trypanosoma brucei aurora B kinase 0.0691 0.0463 0.0529
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0303 0.0069 0.0068
Onchocerca volvulus 0.05 0.0269 0.0337
Brugia malayi phosphoinositide-dependent protein kinase I 0.0244 0.0009 0.0009
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0288 0.0053 0.0061
Loa Loa (eye worm) hypothetical protein 0.0309 0.0074 0.0085
Entamoeba histolytica protein kinase domain containing protein 0.0691 0.0463 0.399
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.1001 0.0779 0.0895
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0851 0.0626 0.0717
Echinococcus granulosus TGF-beta receptor type-1 0.0977 0.0755 0.0867
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Brugia malayi Protein kinase domain containing protein 0.0336 0.0102 0.0117
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0354 0.012 0.0138
Echinococcus granulosus tyrosine protein kinase otk 0.0309 0.0074 0.0085
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni protein kinase 0.0368 0.0134 0.0339
Schistosoma mansoni hypothetical protein 0.0245 0.0009 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.0169 0.0431
Brugia malayi STE20-like kinase MST 0.0439 0.0207 0.0237
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Brugia malayi hypothetical protein 0.0268 0.0032 0.0037
Onchocerca volvulus 0.0268 0.0032 0.003
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0423 0.019 0.1625
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1407 0.1193 0.137
Trichomonas vaginalis protein kinase atn1, putative 0.0268 0.0032 0.0253
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1407 0.1193 0.137
Giardia lamblia Aurora kinase 0.0691 0.0463 0.3827
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Echinococcus granulosus raf serine:threonine protein kinase 0.044 0.0207 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) AUR protein kinase 0.0691 0.0463 0.0532
Entamoeba histolytica protein kinase domain containing protein 0.0379 0.0145 0.124
Echinococcus granulosus casein kinase I alpha 0.0689 0.0462 0.053
Loa Loa (eye worm) hypothetical protein 0.074 0.0513 0.059
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Schistosoma mansoni serine/threonine protein kinase 0.1186 0.0968 0.2587
Echinococcus granulosus TGF beta receptor type 1 0.0977 0.0755 0.0867
Brugia malayi Prion-like- 0.0309 0.0074 0.0085
Echinococcus multilocularis Immunoglobulin 0.0702 0.0475 0.0474
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus multilocularis dual specificity 0.1372 0.1157 0.1156
Echinococcus multilocularis serine:threonine protein kinase 0.0373 0.0139 0.0139
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0614 0.0385 0.0442
Echinococcus multilocularis hemicentin 1 0.0309 0.0074 0.0074
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1294 0.1077 0.1237
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0268 0.0032 0.0032
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0804 0.0578 0.0664
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0373 0.0139 0.016
Echinococcus granulosus tyrosine protein kinase HCK 0.072 0.0493 0.0566
Giardia lamblia Kinase, AGC PKA 0.0328 0.0093 0.0702
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0397 0.0164 0.042
Giardia lamblia Kinase, NEK 0.0268 0.0032 0.0186
Entamoeba histolytica serine/threonine kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase, putative 0.0397 0.0164 0.1403
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.0169 0.0431
Schistosoma mansoni serine/threonine protein kinase 0.0832 0.0607 0.1613
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1055 0.0834 0.0958
Brugia malayi Tyrosine-protein kinase abl-1 0.1463 0.1249 0.1435
Trypanosoma cruzi aurora B kinase, putative 0.0691 0.0463 0.0529
Schistosoma mansoni protein kinase 0.1813 0.1606 0.4307
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1574 0.1363 0.1363
Brugia malayi Protein kinase domain containing protein 0.2661 0.247 0.2837
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0607 0.0378 0.0377
Echinococcus multilocularis protein KINase family member (kin 25) 0.0899 0.0675 0.0675
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0268 0.0032 0.0261
Entamoeba histolytica serine/threonine kinase, putative 0.0268 0.0032 0.0261
Brugia malayi Egg laying defective protein 4 0.0303 0.0069 0.0078
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0268 0.0032 0.0037
Plasmodium falciparum NIMA related kinase 1 0.0305 0.007 0.0633
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1583 0.1372 0.1576
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0762 0.0535 0.0615
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0379 0.0145 0.0145
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.8784 0.8705 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0391 0.0157 0.0181
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0244 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Brugia malayi Variant SH3 domain containing protein 0.0404 0.0171 0.0196
Onchocerca volvulus 0.0436 0.0203 0.0252
Echinococcus granulosus defective proboscis extension response 0.0702 0.0475 0.0545
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0377 0.0143 0.0165
Entamoeba histolytica hypothetical protein 0.027 0.0035 0.0284
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1372 0.1157 0.1326
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1186 0.0968 0.1109
Trypanosoma cruzi protein kinase, putative 0.0268 0.0032 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0521 0.0291 0.2422
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1132 0.0912 0.0912
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0265 0.003 0.0254
Onchocerca volvulus Serine\/threonine kinase homolog 0.0354 0.012 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0246 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.05 0.0269 0.0309
Toxoplasma gondii aurora kinase 0.0691 0.0463 0.4285
Giardia lamblia Kinase, NEK 0.0305 0.007 0.0507
Brugia malayi Protein kinase domain containing protein 0.0514 0.0283 0.0325
Schistosoma mansoni serine/threonine protein kinase 0.0555 0.0325 0.0852
Brugia malayi Immunoglobulin I-set domain containing protein 0.0436 0.0203 0.0233
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0538 0.0307 0.0353
Echinococcus granulosus protein kinase shaggy 0.1294 0.1077 0.1237
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0009 0.0053
Echinococcus multilocularis tyrosine protein kinase otk 0.0309 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0494 0.0263 0.0302
Schistosoma mansoni protein kinase 0.0689 0.0462 0.1222
Trichomonas vaginalis CK1 family protein kinase 0.0689 0.0462 0.3859
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Plasmodium falciparum glycogen synthase kinase 3 0.1294 0.1077 1
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Schistosoma mansoni tyrosine kinase 0.1521 0.1309 0.3507
Schistosoma mansoni serine/threonine kinase 0.0614 0.0385 0.1016
Echinococcus granulosus casein kinase I delta 0.0689 0.0462 0.053
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2661 0.247 0.2469
Loa Loa (eye worm) serine/threonine protein kinase 0.0268 0.0032 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.1769 0.1561 0.4188
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0719
Brugia malayi casein kinase 1, delta 0.0689 0.0462 0.053
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0404 0.0171 0.0437
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1186 0.0968 0.1109
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0404 0.0171 0.0437
Brugia malayi serine/threonine protein kinase 6 0.0691 0.0463 0.0531
Echinococcus multilocularis tyrosine protein kinase csk 0.0268 0.0032 0.0032
Brugia malayi Protein kinase c protein 2 0.0408 0.0175 0.0201
Loa Loa (eye worm) hypothetical protein 0.0702 0.0475 0.0545
Entamoeba histolytica serine/threonine protein kinase, putative 0.0354 0.012 0.1024
Trypanosoma cruzi casein kinase, putative 0.0689 0.0462 0.0528
Schistosoma mansoni serine/threonine protein kinase 0.0832 0.0607 0.1613
Echinococcus granulosus tyrosine protein kinase pr2 0.0268 0.0032 0.0037
Leishmania major casein kinase II, putative 0.0265 0.003 0.0031
Schistosoma mansoni nck2/grb4 0.0412 0.0179 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.1738 0.1529 0.4101
Entamoeba histolytica protein kinase, putative 0.0799 0.0574 0.4949
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0607 0.0378 0.3492
Loa Loa (eye worm) hypothetical protein 0.0851 0.0626 0.072
Loa Loa (eye worm) hypothetical protein 0.0568 0.0338 0.0389
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0009 0.001
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0607 0.0378 0.0377
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0851 0.0626 0.0717
Brugia malayi Protein kinase domain containing protein 0.0354 0.012 0.0138
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0461 0.0229 0.0263
Entamoeba histolytica casein kinase 1, putative 0.0689 0.0462 0.398
Trypanosoma cruzi casein kinase, putative 0.0689 0.0462 0.0528
Echinococcus multilocularis protein kinase shaggy 0.1294 0.1077 0.1077
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1132 0.0912 0.0912
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.012 0.0992
Onchocerca volvulus 0.083 0.0605 0.0774
Loa Loa (eye worm) TK/ROR protein kinase 0.0475 0.0243 0.0279
Brugia malayi Protein kinase domain containing protein 0.0373 0.0139 0.0159
Echinococcus multilocularis ephrin type A receptor 4 A 0.0339 0.0105 0.0104
Echinococcus multilocularis growth factor receptor bound protein 2 0.0412 0.0179 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trypanosoma cruzi casein kinase, putative 0.0689 0.0462 0.0528
Schistosoma mansoni serine/threonine protein kinase 0.0614 0.0385 0.1016
Trypanosoma brucei cdc2-related kinase 1 0.0521 0.0291 0.0331
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0607 0.0378 0.0434
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0244 0.0008 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Entamoeba histolytica cell division protein kinase 2, putative 0.0565 0.0335 0.2885
Plasmodium vivax serine/threonine kinase-1, putative 0.1186 0.0968 0.898
Schistosoma mansoni tyrosine kinase 0.0505 0.0274 0.0715
Entamoeba histolytica protein kinase, putative 0.0308 0.0074 0.0617
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) TK/ALK protein kinase 0.5265 0.5122 0.5884
Echinococcus multilocularis serine:threonine protein kinase N2 0.0614 0.0385 0.0385
Echinococcus granulosus epidermal growth factor receptor 0.1116 0.0896 0.1029
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0836 0.0611 0.0702
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1132 0.0912 0.0912
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.8784 0.8705 1
Loa Loa (eye worm) hypothetical protein 0.074 0.0513 0.059
Echinococcus granulosus tyrosine kinase 0.05 0.0269 0.0308
Schistosoma mansoni roundabout 0.0309 0.0074 0.0177
Brugia malayi cell division control protein 2 homolog 0.0521 0.0291 0.0334
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1294 0.1077 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0851 0.0626 0.072
Giardia lamblia Kinase 0.0268 0.0032 0.0186
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0354 0.012 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.05 0.0269 0.0308
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0402 0.0169 0.0194
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0521 0.0291 0.2682
Echinococcus granulosus activated cdc42 kinase 1 0.1908 0.1702 0.1955
Onchocerca volvulus 0.0923 0.07 0.0897
Loa Loa (eye worm) hypothetical protein 0.082 0.0594 0.0683
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Echinococcus multilocularis tyrosine protein kinase shark 0.0737 0.051 0.0509
Leishmania major protein kinase, putative 0.0607 0.0378 0.0431
Loa Loa (eye worm) hypothetical protein 0.0512 0.0281 0.0323
Onchocerca volvulus Tyrosine kinase homolog 0.3303 0.3124 0.4045
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0607 0.0378 0.3492
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0244 0.0009 0.001
Schistosoma mansoni tyrosine kinase 0.0694 0.0467 0.1236
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0521 0.0291 0.0334
Entamoeba histolytica casein kinase, putative 0.0265 0.003 0.0237
Giardia lamblia Kinase, STE STE20 0.0248 0.0012 0.0015
Brugia malayi Tyrosine-protein kinase PR2 0.0268 0.0032 0.0037
Schistosoma mansoni protein kinase 0.0268 0.0032 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.044 0.0207 0.0536
Brugia malayi serine/threonine-protein kinase PAK 7 0.2422 0.2226 0.2557
Echinococcus granulosus retinal guanylyl cyclase 2 0.0268 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0245 0.0009 0.001
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0689 0.0462 0.053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0347 0.0113 0.0129
Brugia malayi Protein kinase domain containing protein 0.0899 0.0675 0.0776
Brugia malayi protein C17H12.11 0.0671 0.0443 0.0509
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Plasmodium vivax protein kinase, putative 0.0285 0.0049 0.0438
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Onchocerca volvulus 0.1294 0.1077 0.1387
Loa Loa (eye worm) AGC/AKT protein kinase 0.0799 0.0574 0.0659
Echinococcus multilocularis dual specificity 0.0308 0.0074 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0139 0.0353
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1132 0.0912 0.0912
Loa Loa (eye worm) TK protein kinase 0.0268 0.0032 0.0037
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Entamoeba histolytica protein kinase, putative 0.1294 0.1077 0.9314
Echinococcus multilocularis MAM 0.0344 0.011 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.0009 0.0059
Entamoeba histolytica protein kinase, putative 0.0691 0.0463 0.399
Loa Loa (eye worm) AGC/NDR protein kinase 0.0614 0.0385 0.0443
Onchocerca volvulus 0.0344 0.011 0.0131
Loa Loa (eye worm) hypothetical protein 0.1011 0.0789 0.0906
Brugia malayi Furin-like cysteine rich region family protein 0.1116 0.0896 0.1029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0347 0.0113 0.0129
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0689 0.0462 0.0528
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Trichomonas vaginalis STE family protein kinase 0.0397 0.0164 0.136
Brugia malayi Protein kinase domain 0.0421 0.0189 0.0216
Brugia malayi Serine/threonine-protein kinase SULU 0.289 0.2703 0.3105
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0661 0.0432 0.0496
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Entamoeba histolytica protein kinase, putative 0.0608 0.0379 0.3265
Entamoeba histolytica tyrosin kinase, putative 0.0268 0.0032 0.0261
Echinococcus granulosus tyrosine protein kinase Lyn 0.1323 0.1107 0.1271
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.156 0.1348 0.1348
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0689 0.0462 0.1222
Entamoeba histolytica protein kinase domain containing protein 0.0319 0.0085 0.0716
Giardia lamblia Kinase, NEK 0.0268 0.0032 0.0186
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Loa Loa (eye worm) hypothetical protein 0.0923 0.07 0.0804
Brugia malayi p70 ribosomal S6 kinase beta 0.0752 0.0525 0.0603
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0248 0.0012 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0011 0.0074
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0012 0.0011
Schistosoma mansoni protein kinase 0.1055 0.0834 0.2225
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) hypothetical protein 0.1011 0.0789 0.0906
Echinococcus multilocularis dual specificity mitogen activated protein 0.1407 0.1193 0.1193
Echinococcus granulosus titin 0.0436 0.0203 0.0233
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.8784 0.8705 1
Loa Loa (eye worm) hypothetical protein 0.0343 0.0109 0.0126
Echinococcus multilocularis FL cytokine receptor 0.0268 0.0032 0.0032
Echinococcus granulosus tyrosine protein kinase csk 0.0268 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0347 0.0113 0.013
Echinococcus granulosus tyrosine protein kinase Src64B 0.1132 0.0912 0.1048
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0626
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0555 0.0325 0.0372
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Brugia malayi Protein kinase domain containing protein 0.05 0.0269 0.0308
Trypanosoma brucei protein kinase, putative 0.0459 0.0227 0.0258
Brugia malayi serine/threonine-protein kinase plk-2 0.0354 0.012 0.0138
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0347 0.0113 0.0282
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0268 0.0032 0.0064
Loa Loa (eye worm) TK protein kinase 0.0268 0.0032 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Echinococcus multilocularis protein tyrosine kinase 0.3885 0.3716 0.3716
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0328 0.0093 0.0848
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0012 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.1132 0.0912 0.1048
Onchocerca volvulus Serine\/threonine kinase homolog 0.0336 0.0102 0.0121
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0268 0.0032 0.0064
Trichomonas vaginalis STE family protein kinase 0.0268 0.0032 0.0253
Brugia malayi Protein kinase domain containing protein 0.1372 0.1157 0.1328
Entamoeba histolytica SH2-protein kinase domain containing protein 0.05 0.0269 0.2306
Entamoeba histolytica serine/threonine kinase, putative 0.0268 0.0032 0.0261
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0459 0.0227 0.0258
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0521 0.0291 0.0331
Echinococcus multilocularis casein kinase i 0.0689 0.0462 0.0461
Echinococcus granulosus hypothetical protein 0.0996 0.0774 0.0888
Echinococcus granulosus serine:threonine protein kinase 0.0373 0.0139 0.0159
Giardia lamblia Kinase, CAMK CAMKL 0.0445 0.0213 0.1715
Loa Loa (eye worm) AGC/PKG protein kinase 0.0303 0.0069 0.0079
Entamoeba histolytica tyrosin kinase, putative 0.0268 0.0032 0.0261
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0268 0.0032 0.0037
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2442 0.2247 0.2247
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1738 0.1529 0.1757
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2661 0.247 0.2837
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0475 0.0243 0.0243
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2181 0.1981 0.2275
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0347 0.0113 0.0113
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0607 0.0378 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0762 0.0535 0.0615
Brugia malayi protein-tyrosine kinase 0.0952 0.0729 0.0838
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0309 0.0074 0.0177
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0412 0.0179 0.0459
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0977 0.0755 0.0755
Echinococcus multilocularis serine:threonine protein kinase 38 0.0614 0.0385 0.0385
Onchocerca volvulus 0.0829 0.0604 0.0773
Entamoeba histolytica PH domain containing protein kinase, putative 0.0899 0.0675 0.5828
Schistosoma mansoni tyrosine kinase 0.2281 0.2082 0.5593
Echinococcus granulosus rho-associated protein kinase 1 0.083 0.0605 0.0695
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Entamoeba histolytica protein kinase domain containing protein 0.0459 0.0227 0.1943
Schistosoma mansoni protein kinase 0.0977 0.0755 0.2013
Loa Loa (eye worm) hypothetical protein 0.0309 0.0074 0.0085
Echinococcus multilocularis insulin receptor 0.1521 0.1309 0.1309
Schistosoma mansoni protein kinase 0.0459 0.0227 0.0588
Schistosoma mansoni protein kinase 0.1407 0.1193 0.3194
Echinococcus multilocularis tyrosine protein kinase HCK 0.072 0.0493 0.0493
Echinococcus granulosus tyrosine protein kinase Fyn 0.1132 0.0912 0.1048
Loa Loa (eye worm) IKK protein kinase 0.7806 0.7709 0.8856
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3246 0.3065 0.3521
Trypanosoma cruzi casein kinase, putative 0.0689 0.0462 0.0528
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0379 0.0145 0.0167
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0308 0.0074 0.0082
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1583 0.1372 0.1371
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1294 0.1077 0.2883
Echinococcus granulosus cyclin dependent kinase 19 0.1769 0.1561 0.1793
Echinococcus granulosus tyrosine protein kinase Fyn 0.1132 0.0912 0.1048
Echinococcus multilocularis heat shock protein 70 0.0268 0.0032 0.0032
Schistosoma mansoni titin 0.0309 0.0074 0.0177
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0752 0.0525 0.0603
Loa Loa (eye worm) hypothetical protein 0.1622 0.1411 0.1621
Plasmodium vivax serine/threonine protein kinase, putative 0.0246 0.001 0.0075
Loa Loa (eye worm) AGC/PKA protein kinase 0.0851 0.0626 0.072
Loa Loa (eye worm) hypothetical protein 0.0312 0.0077 0.0089
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0661 0.0432 0.0432
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0247 0.0011 0.0013
Schistosoma mansoni septate junction protein 0.0309 0.0074 0.0177
Echinococcus multilocularis serine threonine protein kinase 0.066 0.0432 0.0431
Echinococcus multilocularis 0.1051 0.083 0.083
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0689 0.0462 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0379 0.0145 0.0369
Plasmodium vivax unspecified product 0.0265 0.003 0.0254
Giardia lamblia Kinase, NEK 0.0305 0.007 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.1186 0.0968 0.2587
Echinococcus multilocularis mitogen activated protein kinase 3 0.0247 0.0011 0.0011
Loa Loa (eye worm) TK/RYK protein kinase 0.0268 0.0032 0.0037
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0652 0.0423 0.0486
Trypanosoma brucei protein kinase, putative 0.0291 0.0056 0.0061
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0336 0.0102 0.0102
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0268 0.0032 0.0032
Echinococcus granulosus dual specificity protein kinase clk2 0.1186 0.0968 0.1111
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0762 0.0535 0.0612
Loa Loa (eye worm) gastrulation defective protein 1 0.1579 0.1367 0.1571
Entamoeba histolytica protein kinase, putative 0.072 0.0493 0.4253
Brugia malayi Protein kinase domain containing protein 0.2181 0.1981 0.2275
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0702 0.0475 0.1257
Giardia lamblia Kinase, CMGC CLK 0.1186 0.0968 0.8096
Trichomonas vaginalis STE family protein kinase 0.1407 0.1193 1
Schistosoma mansoni protein kinase 0.2661 0.247 0.6638
Schistosoma mansoni serine/threonine protein kinase 0.0851 0.0626 0.1667
Brugia malayi Protein kinase domain containing protein 0.7806 0.7709 0.8856
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0268 0.0032 0.0037
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0421 0.0189 0.0188
Echinococcus multilocularis transfer RNA-Thr 0.1908 0.1702 0.1702
Leishmania major hypothetical protein, conserved 0.0268 0.0032 0.0035
Brugia malayi hypothetical protein 0.0762 0.0535 0.0615
Loa Loa (eye worm) hypothetical protein 0.0309 0.0074 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.0009 0.0059
Brugia malayi MAP kinase sur-1 0.0247 0.0011 0.0012
Onchocerca volvulus 0.0268 0.0032 0.003
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus multilocularis serine:threonine protein kinase N2 0.129 0.1074 0.1073
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0047 0.0372
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Schistosoma mansoni septate junction protein 0.0309 0.0074 0.0177
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0074 0.0085
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Trichomonas vaginalis STE family protein kinase 0.0421 0.0189 0.1566
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Echinococcus granulosus cGMP dependent protein kinase 1 0.0303 0.0069 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.0169 0.0431
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1539 0.1326 0.1326
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus multilocularis serine:threonine protein kinase N2 0.1905 0.1699 0.1699
Echinococcus granulosus serine:threonine protein kinase 0.0373 0.0139 0.0159
Schistosoma mansoni tyrosine kinase 0.0737 0.051 0.1352
Schistosoma mansoni serine/threonine protein kinase 0.1178 0.0959 0.2564
Brugia malayi hypothetical protein 0.0344 0.011 0.0126
Schistosoma mansoni growth factor receptor-bound protein 0.043 0.0197 0.0508
Plasmodium falciparum calcium-dependent protein kinase 5 0.0607 0.0378 0.3492
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Loa Loa (eye worm) TK/DDR protein kinase 0.0343 0.0109 0.0126
Echinococcus granulosus serine:threonine kinase SAD 1 0.0402 0.0169 0.0193
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0762 0.0535 0.0612
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0555 0.0325 0.0372
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0439 0.0207 0.0237
Onchocerca volvulus 0.05 0.0269 0.0337
Entamoeba histolytica protein kinase, putative 0.0752 0.0525 0.4529
Loa Loa (eye worm) hypothetical protein 0.0762 0.0535 0.0615
Loa Loa (eye worm) thyroid receptor interactor 0.0899 0.0675 0.0775
Schistosoma mansoni titin 0.0245 0.0009 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0139 0.0353
Onchocerca volvulus 0.0268 0.0032 0.003
Echinococcus multilocularis cyclin dependent kinase 9 0.0485 0.0253 0.0253
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Echinococcus multilocularis cyclin dependent kinase 9 0.0441 0.0208 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.074 0.0513 0.059
Trichomonas vaginalis AGC family protein kinase 0.0799 0.0574 0.4799
Echinococcus multilocularis protein kinase 0.0268 0.0032 0.0032
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0851 0.0626 0.0717
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Onchocerca volvulus 0.1049 0.0828 0.1063
Trichomonas vaginalis STE family protein kinase 0.1407 0.1193 1
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0074 0.0598
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0851 0.0626 0.0717
Schistosoma mansoni serine/threonine-protein kinase 0.0375 0.0142 0.036
Echinococcus granulosus peroxidasin 0.0312 0.0077 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.0032 0.0253
Brugia malayi serine/threonine kinase 12 0.0691 0.0463 0.0531
Brugia malayi Immunoglobulin I-set domain containing protein 0.3901 0.3732 0.4287
Onchocerca volvulus 0.7806 0.7709 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0404 0.0171 0.0196
Brugia malayi SRC-1 0.1132 0.0912 0.1048
Schistosoma mansoni tyrosine kinase 0.1521 0.1309 0.3507
Loa Loa (eye worm) hypothetical protein 0.0631 0.0403 0.0463
Echinococcus granulosus expressed protein 0.0246 0.001 0.0012
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1294 0.1077 0.1235
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0402 0.0169 0.0191
Trypanosoma brucei casein kinase I, isoform 2 0.0689 0.0462 0.0528
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Schistosoma mansoni tyrosine kinase 0.0962 0.074 0.1972
Schistosoma mansoni serine/threonine protein kinase 0.289 0.2703 0.7268
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0607 0.0378 0.3492
Echinococcus multilocularis roundabout 2 0.1049 0.0828 0.0828
Echinococcus multilocularis cyclin dependent kinase 7 0.0701 0.0473 0.0473
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0402 0.0169 0.0191
Echinococcus granulosus mitogen activated protein kinase 0.0247 0.0011 0.0012
Trichomonas vaginalis CK1 family protein kinase 0.0689 0.0462 0.3859
Giardia lamblia Kinase, CMGC CK2 0.0265 0.003 0.0162
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0268 0.0032 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0691 0.0463 0.399
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0268 0.0032 0.0032
Echinococcus granulosus serine/threonine protein kinase 0.0375 0.0142 0.0163
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0402 0.0169 0.0191
Entamoeba histolytica protein kinase, putative 0.0246 0.001 0.007
Echinococcus granulosus integrin linked protein kinase 0.0268 0.0032 0.0037
Schistosoma mansoni cell adhesion molecule 0.0245 0.0009 0.0001
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0309 0.0074 0.0074
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0247 0.0011 0.001
Brugia malayi intracellular kinase 0.1294 0.1077 0.1237
Entamoeba histolytica hypothetical protein, conserved 0.0268 0.0032 0.0261
Onchocerca volvulus 0.0382 0.0149 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0102 0.0252
Echinococcus multilocularis neuroglian 0.0347 0.0113 0.0113
Onchocerca volvulus 0.0268 0.0032 0.003
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0247 0.0011 0.001
Loa Loa (eye worm) TK/EGFR protein kinase 0.1116 0.0896 0.103
Schistosoma mansoni ephrin receptor 0.0306 0.0071 0.0169
Brugia malayi Fibronectin type III domain containing protein 0.074 0.0513 0.059
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) AUR protein kinase 0.0691 0.0463 0.0532
Giardia lamblia Kinase, NEK 0.0305 0.007 0.0507
Entamoeba histolytica protein kinase, putative 0.0244 0.0009 0.0054
Echinococcus granulosus protein tyrosine kinase 0.3885 0.3716 0.4269
Entamoeba histolytica protein kinase domain containing protein 0.0441 0.0208 0.1786
Toxoplasma gondii histone kinase SNF1, putative 0.0402 0.0169 0.1546
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0691 0.0463 0.0531
Brugia malayi hypothetical protein 0.074 0.0513 0.059
Echinococcus granulosus casein kinase I gamma 0.0391 0.0157 0.018
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0514 0.0283 0.0325
Brugia malayi Immunoglobulin I-set domain containing protein 0.1781 0.1573 0.1807
Loa Loa (eye worm) protein kinase domain-containing protein 0.0268 0.0032 0.0037
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0268 0.0032 0.0035
Trypanosoma brucei polo-like protein kinase 0.0354 0.012 0.0136
Loa Loa (eye worm) CAMK protein kinase 0.0436 0.0203 0.0233
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2215 0.2016 0.2016
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Schistosoma mansoni serine/threonine protein kinase 0.3246 0.3065 0.8243
Loa Loa (eye worm) hypothetical protein 0.1051 0.083 0.0954
Trichomonas vaginalis CMGC family protein kinase 0.0521 0.0291 0.2422
Brugia malayi casein kinase I 0.0689 0.0462 0.053
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Trichomonas vaginalis AGC family protein kinase 0.0691 0.0463 0.3869
Echinococcus granulosus serine threonine protein kinase nrc 0.0328 0.0093 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Onchocerca volvulus 0.0268 0.0032 0.003
Trypanosoma brucei Casein kinase II 0.0265 0.003 0.0031
Echinococcus granulosus cyclin dependent kinase 1 0.0521 0.0291 0.0334
Entamoeba histolytica protein kinase, putative 0.0423 0.019 0.1625
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.003 0.0229
Echinococcus multilocularis kinase suppressor of Ras 1 0.0268 0.0032 0.0032
Echinococcus granulosus tyrosine protein kinase ABL1 0.2548 0.2355 0.2705
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0379 0.0145 0.0167
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0513 0.0282 0.0324
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2478 0.2284 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0268 0.0032 0.0037
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0607 0.0378 0.3492
Echinococcus granulosus NDR protein kinase 0.0614 0.0385 0.0442
Trichomonas vaginalis STE family protein kinase 0.1407 0.1193 1
Leishmania major protein kinase, putative 0.0268 0.0032 0.0035
Echinococcus multilocularis tyrosine protein kinase Srms 0.0952 0.0729 0.0729
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Plasmodium falciparum cGMP-dependent protein kinase 0.0303 0.0069 0.0616
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0315 0.008 0.0092
Loa Loa (eye worm) hypothetical protein 0.0412 0.0179 0.0205
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0309 0.0074 0.0085
Trypanosoma cruzi cdc2-related kinase 3 0.0521 0.0291 0.0331
Brugia malayi Protein kinase domain containing protein 0.0268 0.0032 0.0037
Echinococcus multilocularis cyclin dependent kinase 1 0.0521 0.0291 0.029
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1294 0.1077 0.1077
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1132 0.0912 0.0912
Trichomonas vaginalis AGC family protein kinase 0.0662 0.0434 0.3626
Brugia malayi Protein kinase domain containing protein 0.3928 0.376 0.4319
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni protein kinase 0.1051 0.083 0.2215
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0247 0.0011 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0074 0.0175
Echinococcus multilocularis dual specificity 0.0308 0.0074 0.0073
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1583 0.1372 0.1576
Brugia malayi serine/threonine-protein kinase 6 0.0691 0.0463 0.0531
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0691 0.0463 0.4285
Echinococcus granulosus slit 2 protein 0.0303 0.0068 0.0078
Echinococcus granulosus ephrin type A receptor 4 A 0.0339 0.0105 0.012
Echinococcus multilocularis expressed protein 0.0246 0.001 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0836 0.0611 0.0702
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0607 0.0378 0.3492
Entamoeba histolytica protein kinase, putative 0.0607 0.0378 0.3252
Entamoeba histolytica serine/threonine kinase, putative 0.0268 0.0032 0.0261
Plasmodium falciparum serine/threonine protein kinase KIN 0.0402 0.0169 0.1546
Echinococcus multilocularis activated cdc42 kinase 1 0.1908 0.1702 0.1702
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0074 0.0598
Entamoeba histolytica protein kinase domain containing protein 0.1294 0.1077 0.9314
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0607 0.0378 0.3492
Brugia malayi Protein kinase domain containing protein 0.05 0.0269 0.0308
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Echinococcus multilocularis protein kinase c iota type 0.0878 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.05 0.0269 0.0309
Loa Loa (eye worm) TK protein kinase 0.0268 0.0032 0.0037
Echinococcus granulosus Immunoglobulin 0.0702 0.0475 0.0545
Leishmania major protein kinase, putative 0.1186 0.0968 0.1109
Entamoeba histolytica protein kinase 2, putative 0.0328 0.0093 0.079
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1178 0.0959 0.0959
Giardia lamblia Kinase, STE STE20 0.1407 0.1193 1
Brugia malayi Protein kinase domain containing protein 0.0246 0.001 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.0268 0.0032 0.0037
Onchocerca volvulus 0.0689 0.0462 0.0588
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0464 0.0232 0.0267
Entamoeba histolytica protein kinase, putative 0.0268 0.0032 0.0261
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0521 0.0291 0.0761
Echinococcus granulosus calcium dependent protein kinase 0.0416 0.0184 0.0211
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0268 0.0032 0.0037
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0851 0.0626 0.5805
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.051 0.0279 0.032
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2215 0.2016 0.2315
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0268 0.0032 0.0064
Echinococcus multilocularis epidermal growth factor receptor 0.1116 0.0896 0.0896
Entamoeba histolytica receptor protein kinase, putative 0.0268 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0899 0.0675 0.0776
Brugia malayi SH2 domain containing protein 0.05 0.0269 0.0308
Plasmodium falciparum tyrosine kinase-like protein 0.0268 0.0032 0.028
Schistosoma mansoni serine/threonine protein kinase 0.1905 0.1699 0.456
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0421 0.0189 0.0188
Echinococcus granulosus protein kinase C gamma type 0.066 0.0432 0.0495
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0268 0.0032 0.028
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2478 0.2284 0.2623
Trichomonas vaginalis CMGC family protein kinase 0.1294 0.1077 0.903
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1769 0.1561 0.1794
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Schistosoma mansoni protein kinase 0.2563 0.237 0.6369
Echinococcus granulosus serine:threonine protein kinase N2 0.1905 0.1699 0.1952
Trypanosoma cruzi protein kinase, putative 0.0268 0.0032 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1162 0.0943 0.1081
Loa Loa (eye worm) hypothetical protein 0.0923 0.07 0.0804
Echinococcus multilocularis lachesin 0.0309 0.0074 0.0074
Brugia malayi hypothetical protein 0.289 0.2703 0.3105
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) hypothetical protein 0.074 0.0513 0.059
Echinococcus multilocularis tyrosine protein kinase csk 0.0268 0.0032 0.0032
Echinococcus granulosus cyclin dependent kinase 7 0.0701 0.0473 0.0544
Echinococcus multilocularis mitogen activated protein kinase 14 0.8784 0.8705 0.8705
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Brugia malayi hypothetical protein 0.0671 0.0443 0.0509
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2478 0.2284 0.2954
Schistosoma mansoni tyrosine kinase 0.0679 0.0452 0.1195
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0268 0.0032 0.0253
Schistosoma mansoni cell adhesion molecule 0.0347 0.0113 0.0282
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.1141 0.0922 0.2463
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Entamoeba histolytica hypothetical protein 0.0268 0.0032 0.0261
Schistosoma mansoni hypothetical protein 0.0344 0.011 0.0273
Trypanosoma cruzi polo-like protein kinase, putative 0.0354 0.012 0.0136
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1294 0.1077 0.1235
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Loa Loa (eye worm) TK protein kinase 0.072 0.0493 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.1372 0.1157 0.3096
Brugia malayi Temporarily assigned gene name protein 59 0.0762 0.0535 0.0615
Plasmodium vivax casein kinase 1, putative 0.0689 0.0462 0.4274
Loa Loa (eye worm) RGC/RGC protein kinase 0.0268 0.0032 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Brugia malayi Raf kinase 0.0268 0.0032 0.0037
Entamoeba histolytica hypothetical protein 0.0271 0.0036 0.0291
Echinococcus multilocularis casein kinase I alpha 0.0689 0.0462 0.0461
Schistosoma mansoni myosin-binding protein-related 0.0245 0.0009 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0011 0.0074
Loa Loa (eye worm) AGC/PKN protein kinase 0.1905 0.1699 0.1952
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus activated cdc42 kinase 1 0.1908 0.1702 0.1955
Loa Loa (eye worm) hypothetical protein 0.0568 0.0338 0.0389
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.012 0.0992
Echinococcus granulosus retinal guanylyl cyclase 2 0.0268 0.0032 0.0037
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0248 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0762 0.0535 0.142
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0244 0.0009 0.0008
Echinococcus multilocularis serine:threonine protein kinase 0.0373 0.0139 0.0139
Loa Loa (eye worm) TK/ACK protein kinase 0.0268 0.0032 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0139 0.0353
Echinococcus multilocularis protein kinase 0.0268 0.0032 0.0032
Onchocerca volvulus 0.05 0.0269 0.0337
Loa Loa (eye worm) hypothetical protein 0.0268 0.0032 0.0037
Brugia malayi C1-like domain containing protein 0.1192 0.0973 0.1118
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0282 0.0047 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0169 0.1396
Schistosoma mansoni ste20-related kinase 0.0382 0.0148 0.0377
Giardia lamblia Kinase, PLK 0.0354 0.012 0.0931
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0265 0.003 0.0034
Leishmania major protein kinase A catalytic subunit isoform 1 0.0851 0.0626 0.0717
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Echinococcus granulosus tyrosine protein kinase 0.0268 0.0032 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.1178 0.0959 0.2564
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2478 0.2284 0.2623
Brugia malayi Hr1 repeat family protein 0.1905 0.1699 0.1952
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni ephrin receptor 0.0339 0.0105 0.0259
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Plasmodium vivax protein kinase Crk2 0.0521 0.0291 0.2682
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0069 0.0162
Loa Loa (eye worm) hypothetical protein 0.0705 0.0478 0.0549
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0347 0.0113 0.0129
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0521 0.0291 0.0331
Loa Loa (eye worm) TK/ABL protein kinase 0.2548 0.2355 0.2705
Echinococcus multilocularis receptor type guanylyl cyclase 0.0268 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0309 0.0074 0.0085
Plasmodium falciparum tyrosine kinase-like protein 0.0268 0.0032 0.028
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1186 0.0968 0.1112
Brugia malayi Protein kinase domain containing protein 0.1769 0.1561 0.1793
Entamoeba histolytica hypothetical protein 0.0271 0.0036 0.0291
Toxoplasma gondii STE kinase 0.0268 0.0032 0.028
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1141 0.0922 0.1059
Echinococcus granulosus tyrosine protein kinase Srms 0.0952 0.0729 0.0837
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0074 0.0085
Schistosoma mansoni titin 0.0436 0.0203 0.0525
Toxoplasma gondii CMGC kinase, CK2 family 0.0265 0.003 0.0254
Giardia lamblia Kinase, CMGC DYRK 0.0308 0.0074 0.0534
Echinococcus multilocularis expressed conserved protein 0.0303 0.0069 0.0068
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1132 0.0912 0.0912
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1622 0.1411 0.1621
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0309 0.0074 0.0085
Echinococcus granulosus NCK adaptor protein 0.0412 0.0179 0.0205
Echinococcus granulosus tyrosine protein kinase Src42A 0.1132 0.0912 0.1048
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0032 0.0064
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0804 0.0578 0.0664
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0391 0.0157 0.0401
Brugia malayi Protein kinase domain containing protein 0.0368 0.0134 0.0154
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1192 0.0973 0.1118
Schistosoma mansoni cell adhesion molecule 0.0309 0.0074 0.0177
Brugia malayi Stress-activated protein kinase jnk-1 0.3246 0.3065 0.352
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0862 0.0637 0.0732
Plasmodium falciparum serine/threonine protein kinase, putative 0.0691 0.0463 0.4285
Echinococcus multilocularis dual specificity 0.0308 0.0074 0.0073
Plasmodium falciparum protein kinase, putative 0.0268 0.0032 0.028
Entamoeba histolytica tyrosine kinase, putative 0.0268 0.0032 0.0261
Echinococcus granulosus protein kinase 0.1051 0.083 0.0953
Brugia malayi Doublecortin family protein 0.0321 0.0087 0.0099
Entamoeba histolytica protein kinase, putative 0.0271 0.0036 0.0291
Onchocerca volvulus 0.064 0.0411 0.0522
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0074 0.0598
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0268 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.05 0.0269 0.0309
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0268 0.0032 0.0261
Schistosoma mansoni tyrosine protein kinase 0.0268 0.0032 0.0064
Brugia malayi protein unc-22 0.0436 0.0203 0.0233
Trichomonas vaginalis CMGC family protein kinase 0.1186 0.0968 0.8109
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0762 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0923 0.07 0.0804
Schistosoma mansoni protein kinase C mu 0.1192 0.0973 0.2602
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0069 0.0162
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0303 0.0069 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0074 0.0085
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0032 0.0261
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0347 0.0113 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0268 0.0032 0.0253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0074 0.0085
Schistosoma mansoni tyrosine kinase 0.0268 0.0032 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0308 0.0074 0.0617
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0851 0.0626 0.0626
Echinococcus granulosus casein kinase i 0.0689 0.0462 0.053
Echinococcus multilocularis tyrosine protein kinase csk 0.0268 0.0032 0.0032
Echinococcus granulosus tyrosine protein kinase csk 0.0268 0.0032 0.0037

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.8913 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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