Detailed information for compound 148282

Basic information

Technical information
  • TDR Targets ID: 148282
  • Name: 3-(diethylamino)-N-[7-[3-(diethylamino)propan oylamino]-9-oxofluoren-2-yl]propanamide
  • MW: 464.6 | Formula: C27H36N4O3
  • H donors: 2 H acceptors: 3 LogP: 2.82 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCC(=O)Nc1ccc2c(c1)C(=O)c1c2ccc(c1)NC(=O)CCN(CC)CC)CC
  • InChi: 1S/C27H36N4O3/c1-5-30(6-2)15-13-25(32)28-19-9-11-21-22-12-10-20(18-24(22)27(34)23(21)17-19)29-26(33)14-16-31(7-3)8-4/h9-12,17-18H,5-8,13-16H2,1-4H3,(H,28,32)(H,29,33)
  • InChiKey: LXKAADAEWLMNAU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(diethylamino)-N-[7-[3-(diethylamino)propanoylamino]-9-oxo-fluoren-2-yl]propanamide
  • 3-(diethylamino)-N-[7-[[3-(diethylamino)-1-oxopropyl]amino]-9-oxo-2-fluorenyl]propanamide
  • 3-(diethylamino)-N-[7-[3-(diethylamino)propanoylamino]-9-keto-fluoren-2-yl]propionamide
  • 3-diethylamino-N-[7-(3-diethylaminopropanoylamino)-9-oxofluoren-2-yl]propanamide
  • 3-diethylamino-N-[7-(3-diethylaminopropanoylamino)-9-oxo-fluoren-2-yl]propanamide
  • 3-diethylamino-N-[7-[(3-diethylamino-1-oxopropyl)amino]-9-oxo-2-fluorenyl]propanamide
  • 3-diethylamino-N-[7-(3-diethylaminopropanoylamino)-9-keto-fluoren-2-yl]propionamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens telomerase reverse transcriptase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans telomerase reverse transcriptase Get druggable targets OG5_131652 All targets in OG5_131652
Onchocerca volvulus Telomerase reverse transcriptase homolog Get druggable targets OG5_131652 All targets in OG5_131652
Candida albicans telomerase reverse transcriptase Get druggable targets OG5_131652 All targets in OG5_131652
Theileria parva hypothetical protein Get druggable targets OG5_131652 All targets in OG5_131652
Brugia malayi Telomerase reverse transcriptase Get druggable targets OG5_131652 All targets in OG5_131652
Babesia bovis conserved hypothetical protein Get druggable targets OG5_131652 All targets in OG5_131652
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0037 0.0075 0.0324
Onchocerca volvulus 0.0037 0.0075 0.0324
Onchocerca volvulus 0.0037 0.0075 0.0324
Onchocerca volvulus 0.0067 0.0171 0.0737
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0016 0.0004 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.011 0.0476
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0016 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0011 0.0033
Schistosoma mansoni hypothetical protein 0.0051 0.0119 0.0119
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.013 0.1707
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0416 0.0415
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0072 0.0187 0.0187
Echinococcus multilocularis importin subunit beta 1 0.0039 0.008 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.013 0.1707
Echinococcus multilocularis allatostatin A receptor 0.0037 0.0075 0.0075
Schistosoma mansoni transcription factor LCR-F1 0.0142 0.042 0.0419
Echinococcus granulosus expressed conserved protein 0.0061 0.0151 0.0151
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.013 0.1707
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.1063 0.3439 0.3439
Echinococcus multilocularis regulator of G protein signaling 7 0.0106 0.03 0.03
Echinococcus granulosus tachykinin peptides receptor 99D 0.0037 0.0075 0.0075
Brugia malayi PHD-finger family protein 0.0071 0.0187 0.0542
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0011 0.0048
Mycobacterium ulcerans beta-lactamase 0.0067 0.0171 0.2249
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0004 0.0016
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0175 0.0527 0.3589
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.013 0.1682
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0016 0.0004 0.0029
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.0077 0.0225
Echinococcus granulosus neuropeptide receptor A26 0.0037 0.0075 0.0075
Trichomonas vaginalis antibiotic synthetase, putative 0.0016 0.0004 0.0019
Brugia malayi steroid hormone receptor 0.0038 0.0077 0.0225
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0051 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Schistosoma mansoni hypothetical protein 0.0037 0.0075 0.0075
Schistosoma mansoni opsin-like receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0053 0.0125 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0106 0.03 0.03
Schistosoma mansoni nuclear receptor 0.0018 0.0011 0.0011
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0023 0.0029 0.0196
Echinococcus multilocularis neuropeptide s receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0077 0.0077
Schistosoma mansoni alkaline phosphatase 0.0121 0.035 0.035
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0037 0.0075 0.0075
Echinococcus multilocularis lysosomal alpha glucosidase 0.0217 0.0664 0.0664
Echinococcus multilocularis regulator of G protein signaling 7 0.0106 0.03 0.03
Giardia lamblia Cyclin A 0.0042 0.0091 0.1183
Onchocerca volvulus 0.0037 0.0075 0.0324
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Trichomonas vaginalis DNA helicase recq1, putative 0.0018 0.0012 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0416 0.0415
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.0077 0.0225
Onchocerca volvulus 0.0037 0.0075 0.0324
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0075 0.0075
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.0077 0.0077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0537 0.0537
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0091 0.0395
Plasmodium vivax SET domain protein, putative 0.0092 0.0254 0.4813
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.011 0.075
Schistosoma mansoni hypothetical protein 0.0037 0.0075 0.0075
Brugia malayi Protein kinase domain containing protein 0.071 0.2281 0.6631
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0024 0.0032 0.0032
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.025 0.0772 1
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0075 0.0075
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0077 0.0205 0.151
Brugia malayi Cytochrome P450 family protein 0.0015 0.0002 0.0006
Brugia malayi G-protein coupled receptor 0.0037 0.0075 0.0218
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.025 0.0772 1
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0079 0.0213 0.0213
Toxoplasma gondii RNA-directed DNA polymerase 0.0103 0.0289 0.4742
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.0077 0.0225
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0032 0.0138
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0496
Schistosoma mansoni alpha-glucosidase 0.0187 0.0565 0.0565
Trypanosoma brucei unspecified product 0.0037 0.0075 0.0511
Loa Loa (eye worm) PXA domain-containing protein 0.0106 0.03 0.0872
Schistosoma mansoni lipoxygenase 0.0099 0.0277 0.0277
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0072 0.0187 0.0187
Plasmodium falciparum pyruvate kinase 0.0025 0.0034 0.0639
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0335 0.0335
Brugia malayi Pyruvate kinase, M2 isozyme 0.0025 0.0034 0.0098
Onchocerca volvulus 0.0018 0.0011 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0078 0.0562
Loa Loa (eye worm) hypothetical protein 0.0035 0.0068 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0022 0.0094
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.0077 0.0077
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0496
Plasmodium vivax thioredoxin reductase, putative 0.0034 0.0063 0.1197
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0106 0.03 0.03
Onchocerca volvulus 0.0037 0.0075 0.0324
Leishmania major acetyl-CoA synthetase, putative 0.0016 0.0004 0.0029
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0632 0.2027 0.5892
Onchocerca volvulus 0.0038 0.0077 0.0334
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0016 0.0004 0.0041
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0072 0.0187 0.0187
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0064 0.0163 0.0473
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0034 0.0034
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0018 0.0011 0.0047
Brugia malayi hypothetical protein 0.0106 0.03 0.0872
Toxoplasma gondii PHD-finger domain-containing protein 0.0071 0.0187 0.306
Entamoeba histolytica hypothetical protein 0.0142 0.042 0.5433
Plasmodium falciparum protein kinase, putative 0.0017 0.0008 0.0159
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0011 0.0011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0027 0.0027
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0055 0.0132 0.0963
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0004 0.0029
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0032 0.0056 0.0243
Brugia malayi hypothetical protein 0.008 0.0216 0.0628
Schistosoma mansoni regulator of G protein signaling 0.0106 0.03 0.03
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0091 0.0091
Schistosoma mansoni neuropeptide receptor 0.0037 0.0075 0.0075
Leishmania major cytochrome p450-like protein 0.0015 0.0002 0.0015
Echinococcus multilocularis pyruvate kinase 0.002 0.0017 0.0016
Brugia malayi Serotonin receptor 0.0037 0.0075 0.0218
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0032 0.0092
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.013 0.0885
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0054 0.013 0.1707
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0109 0.0739
Brugia malayi Steroid receptor seven-up type 2 0.0038 0.0077 0.0225
Schistosoma mansoni pyruvate kinase 0.0025 0.0034 0.0034
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0016 0.0004 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.0077 0.0225
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0026
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0042 0.0091 0.0091
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0175 0.0527 0.8642
Trichomonas vaginalis cyclin D, putative 0.0042 0.0091 0.0395
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0112 0.0325
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0054 0.013 0.2434
Giardia lamblia DINP protein human, muc B family 0.0037 0.0075 0.0971
Trichomonas vaginalis cyclin B3, putative 0.0042 0.0091 0.0395
Echinococcus granulosus cyclin B 0.0102 0.0286 0.0286
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0023 0.0029 0.0472
Brugia malayi Cyclin, N-terminal domain containing protein 0.0102 0.0286 0.0832
Onchocerca volvulus 0.0067 0.0171 0.0737
Schistosoma mansoni aldehyde dehydrogenase 0.02 0.061 0.061
Onchocerca volvulus 0.0018 0.0011 0.0048
Echinococcus granulosus tar DNA binding protein 0.0141 0.0416 0.0415
Entamoeba histolytica pyruvate kinase, putative 0.0017 0.0009 0.0117
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.071 0.2281 0.6631
Echinococcus granulosus L aminoadipate semialdehyde 0.0071 0.0185 0.0185
Toxoplasma gondii hypothetical protein 0.0075 0.0197 0.3225
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.013 0.0885
Trichomonas vaginalis cyclins, putative 0.0102 0.0286 0.1237
Echinococcus granulosus lipoxygenase domain containing protein 0.0035 0.0068 0.0068
Echinococcus multilocularis lipoxygenase domain containing protein 0.0035 0.0068 0.0068
Schistosoma mansoni bromodomain containing protein 0.0096 0.0268 0.0268
Echinococcus granulosus neuropeptide s receptor 0.0037 0.0075 0.0075
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0008 0.0057
Echinococcus multilocularis neutral alpha glucosidase AB 0.0048 0.011 0.011
Brugia malayi putative neuropeptide receptor 0.0037 0.0075 0.0218
Chlamydia trachomatis pyruvate kinase 0.0025 0.0034 0.0817
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0032 0.0217
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0011 0.0048
Plasmodium vivax multidomain scavenger receptor, putative 0.0035 0.0068 0.1291
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0075 0.0511
Schistosoma mansoni cyclins 0.0042 0.0091 0.0091
Echinococcus multilocularis 0.0015 0.0002 0.0002
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0011 0.0011
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0106 0.03 0.03
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Schistosoma mansoni zinc finger protein 0.0032 0.0058 0.0058
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis dna polymerase eta 0.006 0.0149 0.0149
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0075 0.0075
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0025 0.0034 0.0034
Echinococcus multilocularis dro:myosuppressin receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0034 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0537 0.0537
Trypanosoma brucei pyruvate kinase 1 0.0025 0.0034 0.0229
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0086 0.0234 0.172
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.009 0.061
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0171 0.0737
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.0085 0.1106
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0496
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0075 0.0075
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0016 0.0004 0.0071
Leishmania major mitochondrial DNA polymerase beta 0.0462 0.1468 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0086 0.0234 0.172
Schistosoma mansoni tyrosine kinase 0.0401 0.1266 0.1266
Schistosoma mansoni regulator of G protein signaling 0.0106 0.03 0.03
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0132 0.0383
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0055 0.0132 0.0897
Onchocerca volvulus 0.0037 0.0075 0.0324
Loa Loa (eye worm) jmjC domain-containing protein 0.0185 0.0559 0.1626
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0002 0.0006
Brugia malayi follicle stimulating hormone receptor 0.0037 0.0075 0.0218
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.02 0.061 0.061
Brugia malayi GnHR receptor homolog 0.0037 0.0075 0.0218
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0002 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0024 0.0029 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Onchocerca volvulus 0.0054 0.013 0.0562
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0075 0.0075
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0077 0.0077
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0071 0.0185 0.0539
Mycobacterium leprae Probable pyruvate kinase PykA 0.0025 0.0034 0.06
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0539
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0106 0.03 0.03
Schistosoma mansoni neuropeptide receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0308 0.0308
Plasmodium falciparum cyclin 0.0042 0.0091 0.1733
Plasmodium vivax importin-beta 2, putative 0.0039 0.008 0.1527
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0109 0.0108
Echinococcus granulosus serotonin receptor 0.0037 0.0075 0.0075
Mycobacterium ulcerans hypothetical protein 0.0054 0.013 0.1707
Trypanosoma cruzi cyclin 6, putative 0.0102 0.0286 0.1949
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0026 0.0036 0.0245
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Mycobacterium tuberculosis Probable dehydrogenase 0.0077 0.0205 0.151
Brugia malayi glucose-6-phosphate dehydrogenase 0.0079 0.0213 0.0619
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0002 0.0015
Echinococcus granulosus allatostatin A receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0109 0.0315
Brugia malayi Sodium:solute symporter family protein 0.0034 0.0064 0.0187
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0037 0.0075 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0011 0.0048
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0075 0.0075
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0071 0.0185 0.0185
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0401 0.1266 0.1266
Brugia malayi Furin-like cysteine rich region family protein 0.0736 0.2368 0.6885
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0002 0.0015
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.0077 0.0225
Echinococcus multilocularis Regulator of G protein signaling 20 0.0106 0.03 0.03
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0041 0.0784
Schistosoma mansoni aldehyde dehydrogenase 0.02 0.061 0.061
Loa Loa (eye worm) TK/EGFR protein kinase 0.0736 0.2368 0.6885
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0079 0.0213 0.0213
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0072 0.0187 0.2418
Trichomonas vaginalis cyclins, putative 0.0102 0.0286 0.1237
Echinococcus granulosus thioredoxin glutathione reductase 0.0034 0.0065 0.0065
Echinococcus multilocularis thioredoxin glutathione reductase 0.0034 0.0065 0.0065
Echinococcus granulosus lysine specific demethylase 6a 0.0048 0.0109 0.0108
Brugia malayi ecdysone receptor 0.0018 0.0011 0.0033
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0217 0.0664 0.193
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0072 0.0187 0.0808
Schistosoma mansoni tyrosine kinase 0.0386 0.1218 0.1218
Treponema pallidum fructose-bisphosphate aldolase 0.025 0.0772 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0067 0.0171 0.017
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0011 0.0033
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0102 0.0286 0.1949
Loa Loa (eye worm) latrophilin receptor protein 2 0.0024 0.0029 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0032 0.0138
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0011 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0126 0.0365 0.5983
Schistosoma mansoni axis inhibition protein axin 0.0106 0.03 0.03
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0077 0.0205 0.387
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.00000000001019 0.000000000044063
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0171 0.3236
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Trichomonas vaginalis cyclin B, putative 0.0102 0.0286 0.1237
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0077 0.0225
Loa Loa (eye worm) DR-78 0.0018 0.0011 0.0033
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0016 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.004 0.0085 0.0247
Brugia malayi Importin beta-1 subunit 0.0039 0.008 0.0234
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0037 0.0072 0.0072
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0075 0.0075
Echinococcus multilocularis phd:f box containing protein 0.0048 0.0109 0.0108
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0065 0.0165 0.1126
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0034 0.0063 0.0453
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0242 0.0748 0.0748
Schistosoma mansoni opsin-like receptor 0.0037 0.0075 0.0075
Echinococcus granulosus solute carrier family 5 0.0034 0.0064 0.0064
Schistosoma mansoni loxhd1 0.0035 0.0068 0.0068
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0957 0.3091 0.8989
Mycobacterium ulcerans hypothetical protein 0.0243 0.075 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.02 0.061 0.4153
Echinococcus multilocularis geminin 0.0433 0.1374 0.1374
Schistosoma mansoni hypothetical protein 0.0024 0.0029 0.0029
Echinococcus granulosus PHD finger protein rhinoceros 0.0071 0.0187 0.0187
Giardia lamblia Protein 21.1 0.0015 0.0000078307 0.00000016106
Schistosoma mansoni jumonji/arid domain-containing protein 0.0185 0.0559 0.0559
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.011 0.0476
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0077 0.0225
Entamoeba histolytica hypothetical protein 0.0106 0.03 0.3886
Trichomonas vaginalis cyclin B, putative 0.0102 0.0286 0.1237
Trichomonas vaginalis cyclin B, putative 0.0102 0.0286 0.1237
Onchocerca volvulus 0.0035 0.0068 0.0294
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0011 0.0011
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0052 0.0122 0.1606
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0024 0.0032 0.0412
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0137 0.04 0.04
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0027 0.0041 0.0784
Schistosoma mansoni zinc finger protein 0.0022 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0038
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0004 0.0013
Brugia malayi RNA binding protein 0.0141 0.0416 0.1208
Schistosoma mansoni survival motor neuron protein 0.0064 0.0163 0.0163
Schistosoma mansoni protein kinase 0.0017 0.0008 0.0008
Echinococcus multilocularis jumonji domain containing protein 0.0099 0.0278 0.0278
Schistosoma mansoni dihydroorotate dehydrogenase 0.0175 0.0527 0.0527
Echinococcus multilocularis serotonin receptor 0.0037 0.0075 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.0077 0.0225
Trypanosoma cruzi pyruvate kinase 2, putative 0.0025 0.0034 0.0229
Echinococcus multilocularis ubiquitin specific protease 41 0.0024 0.0032 0.0032
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Leishmania major hypothetical protein, conserved 0.0022 0.0026 0.0174
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0011 0.0011
Onchocerca volvulus 0.0037 0.0075 0.0324
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus fetal alzheimer antigen falz 0.0037 0.0072 0.0072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0037 0.0075 0.0075
Schistosoma mansoni axis inhibition protein axin 0.0106 0.03 0.03
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0053
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Echinococcus multilocularis Niemann Pick C1 protein 0.0092 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0053
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0957 0.3091 0.3091
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0106 0.03 0.03
Brugia malayi Serotonin receptor 0.0037 0.0075 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Echinococcus granulosus epidermal growth factor receptor 0.0401 0.1266 0.1266
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0075 0.0971
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0075 0.0075
Plasmodium vivax JmjC domain containing protein 0.0048 0.0109 0.2059
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0075 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.011 0.0476
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0004 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0022 0.0094
Giardia lamblia Fructose-bisphosphate aldolase 0.025 0.0772 1
Schistosoma mansoni alkaline phosphatase 0.0121 0.035 0.035
Schistosoma mansoni hypothetical protein 0.0071 0.0187 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0175 0.0527 1
Brugia malayi hypothetical protein 0.0018 0.0011 0.0033
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0071 0.0187 0.0187
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0077 0.0077
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0011 0.0011
Echinococcus granulosus orexin receptor type 2 0.0037 0.0075 0.0075
Trypanosoma cruzi cyclin, putative 0.0102 0.0286 0.1949
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0037 0.0107
Brugia malayi Dopamine receptor protein 1 0.0037 0.0075 0.0218
Trypanosoma cruzi ISWI complex protein 0.0022 0.0026 0.0174
Loa Loa (eye worm) hypothetical protein 0.0106 0.03 0.0872
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.071 0.2281 0.228
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.0077 0.0077
Echinococcus granulosus integrin linked protein kinase 0.0015 0.0000078307 0.000000012436
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Echinococcus granulosus sodium:glucose cotransporter 0.0034 0.0064 0.0064
Onchocerca volvulus 0.0016 0.0004 0.0019
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0219 0.0669 0.4561
Schistosoma mansoni cpg binding protein 0.0069 0.0179 0.0179
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0091 0.0394
Schistosoma mansoni cpg binding protein 0.0069 0.0179 0.0179
Onchocerca volvulus 0.0071 0.0185 0.0802
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0034 0.0098
Echinococcus granulosus peregrin 0.0075 0.0198 0.0198
Echinococcus granulosus cyclin B3 1 0.0042 0.0091 0.0091
Loa Loa (eye worm) jmjC domain-containing protein 0.0148 0.0436 0.1268
Mycobacterium ulcerans hypothetical protein 0.0067 0.0171 0.2249
Trypanosoma brucei pyruvate kinase 1, putative 0.0025 0.0034 0.0229
Brugia malayi G protein-coupled receptor 0.0037 0.0075 0.0218
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus somatostatin receptor 0.0037 0.0075 0.0075
Schistosoma mansoni opsin-like receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis lipoxygenase domain containing protein 0.0035 0.0068 0.0068
Echinococcus multilocularis lysine specific demethylase 5A 0.0179 0.0539 0.0538
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.0077 0.0077
Onchocerca volvulus Huntingtin homolog 0.008 0.0216 0.0934
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0121 0.035 0.035
Plasmodium falciparum glutathione reductase 0.0034 0.0063 0.1197
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0034 0.0034
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0079 0.0213 0.145
Echinococcus multilocularis jumonji domain containing 1A 0.0048 0.0109 0.0108
Echinococcus multilocularis JmjC domain containing protein 4 0.0048 0.0109 0.0108
Echinococcus multilocularis X box binding protein 1 0.0194 0.059 0.059
Mycobacterium tuberculosis Conserved protein 0.0067 0.0171 0.1251
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0462 0.1468 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0018 0.0018
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0149 0.1018
Entamoeba histolytica hypothetical protein 0.0142 0.042 0.5433
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Entamoeba histolytica hypothetical protein 0.0142 0.042 0.5433
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.0077 0.0334
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0016 0.0004 0.0029
Schistosoma mansoni protein kinase 0.0015 0.0000078307 0.000000012436
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Brugia malayi Thioredoxin reductase 0.0034 0.0063 0.0183
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0008 0.0057
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0075 0.0218
Brugia malayi PXA domain containing protein 0.0106 0.03 0.0872
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.03 0.1298
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0048 0.011 0.032
Echinococcus multilocularis Polycystic kidney disease protein 0.0035 0.0068 0.0068
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0018 0.0011 0.0142
Loa Loa (eye worm) glutathione reductase 0.0034 0.0063 0.0183
Loa Loa (eye worm) hypothetical protein 0.0102 0.0286 0.0832
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0011 0.0048
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.013 0.1682
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Entamoeba histolytica hypothetical protein 0.0142 0.042 0.5433
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0121 0.035 0.035
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0011 0.0075
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0065 0.0164 0.0478
Mycobacterium tuberculosis Probable lipase LipD 0.0067 0.0171 0.1251
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0079 0.0213 0.0619
Loa Loa (eye worm) hypothetical protein 0.0106 0.03 0.0872
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0177 0.0764
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Toxoplasma gondii ABC1 family protein 0.0067 0.0171 0.2796
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0002 0.0015
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0178 0.0537 0.1561
Echinococcus granulosus geminin 0.0433 0.1374 0.1374
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0004 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0043 0.0187
Brugia malayi integrin-linked kinase 0.0015 0.0000078307 0.000000036158
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0038 0.0078 0.0529
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0077 0.0225
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0053
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Giardia lamblia Telomerase catalytic subunit 0.0103 0.0289 0.3743
Brugia malayi Muscleblind-like protein 0.0373 0.1176 0.342
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0068 0.0177 0.0764
Leishmania major acetyl-CoA synthetase, putative 0.0016 0.0004 0.0029
Echinococcus granulosus neuropeptide receptor 0.0037 0.0075 0.0075
Plasmodium falciparum LCCL domain-containing protein 0.0035 0.0068 0.1291
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.011 0.0476
Trypanosoma brucei ISWI complex protein 0.0022 0.0026 0.0174
Trypanosoma brucei trypanothione reductase 0.0034 0.0063 0.043
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0011 0.0011
Giardia lamblia Pyruvate kinase 0.0025 0.0034 0.0436
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0376 0.1186 0.5127
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.0077 0.0077
Leishmania major DNA polymerase eta, putative 0.0034 0.0065 0.0441
Mycobacterium tuberculosis Probable lipase LipE 0.0067 0.0171 0.1251
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.006 0.0148 0.0429
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0099 0.0276 0.0276
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.002 0.0018 0.0208
Schistosoma mansoni biogenic amine receptor 0.0037 0.0075 0.0075
Echinococcus granulosus axis inhibition protein axin 0.0106 0.03 0.03
Trichomonas vaginalis cyclin B, putative 0.0102 0.0286 0.1237
Leishmania major cytochrome p450-like protein 0.0015 0.0002 0.0015
Echinococcus granulosus sex peptide receptor 0.0037 0.0075 0.0075
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.002 0.0018 0.0208
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0011 0.0048
Schistosoma mansoni tyrosine kinase 0.0401 0.1266 0.1266
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0065 0.0165 0.1126
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0175 0.0527 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0016 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0075 0.0075
Brugia malayi regulator of G-protein signaling rgs-7 0.0106 0.03 0.0872
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.004 0.0085 0.3446
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0103 0.0289 0.1969
Echinococcus multilocularis regulator of G protein signaling 0.0106 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus multilocularis sterol regulatory element binding protein 0.0028 0.0043 0.0043
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0077 0.0077
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0075 0.0541
Echinococcus multilocularis cyclin B3 1 0.0042 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Schistosoma mansoni adenoreceptor 0.0037 0.0075 0.0075
Schistosoma mansoni histamine h1 receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0037 0.0075 0.0075
Echinococcus granulosus sterol regulatory element binding protein 0.0028 0.0043 0.0043
Plasmodium vivax telomerase reverse transcriptase, putative 0.0103 0.0289 0.5487
Loa Loa (eye worm) pyruvate kinase-PB 0.0017 0.0009 0.0026
Leishmania major cytochrome p450-like protein 0.0015 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Schistosoma mansoni amine GPCR 0.0037 0.0075 0.0075
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0017 0.0008 0.0137
Toxoplasma gondii aldehyde dehydrogenase 0.02 0.061 1
Onchocerca volvulus 0.0015 0.0000078307 0.000000053776
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0075 0.0218
Echinococcus granulosus cyclins 0.0042 0.0091 0.0091
Echinococcus multilocularis beta adrenergic receptor kinase 0.0109 0.0308 0.0308
Brugia malayi hypothetical protein 0.002 0.0018 0.0053
Brugia malayi A-kinase anchor protein 10, precursor 0.0106 0.03 0.0872
Plasmodium vivax pyruvate kinase, putative 0.0025 0.0034 0.0639
Brugia malayi Cyclin, N-terminal domain containing protein 0.0042 0.0091 0.0266
Schistosoma mansoni hypothetical protein 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0106 0.03 0.0872
Echinococcus granulosus g protein coupled receptor 0.0037 0.0075 0.0075
Brugia malayi PHD-finger family protein 0.003 0.005 0.0144
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0144
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0037 0.0075 0.0075
Echinococcus multilocularis epidermal growth factor receptor 0.0736 0.2368 0.2368
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0425 0.1347 1
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Brugia malayi Melatonin receptor type 1A 0.0037 0.0075 0.0218
Echinococcus multilocularis G protein coupled receptor 139 0.0037 0.0075 0.0075
Schistosoma mansoni chromobox protein 0.0042 0.0091 0.0091
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.0077 0.0077
Schistosoma mansoni phosphatidylserine receptor 0.0048 0.0109 0.0108
Onchocerca volvulus 0.0099 0.0276 0.1195
Echinococcus multilocularis axis inhibition protein axin 0.0106 0.03 0.03
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0079 0.0213 0.2586
Loa Loa (eye worm) doublecortin family protein 0.0035 0.0068 0.0198
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0254 0.4159
Schistosoma mansoni hypothetical protein 0.0035 0.0068 0.0068
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0037 0.0075 0.0218
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0016 0.0004 0.0016
Onchocerca volvulus 0.0102 0.0286 0.1237
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.0077 0.0077
Echinococcus multilocularis pyruvate kinase 0.0025 0.0034 0.0034
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0054 0.013 0.1707
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0496
Schistosoma mansoni protein kinase 0.0015 0.0000078307 0.000000012436
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0067 0.0171 0.1251
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0067 0.0171 0.2249
Echinococcus multilocularis neuropeptide receptor A26 0.0037 0.0075 0.0075
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0077 0.0077
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0079 0.0213 0.145
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.0537 0.0537
Echinococcus granulosus g protein coupled receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0066 0.0169 0.049
Schistosoma mansoni hypothetical protein 0.0024 0.0029 0.0029
Brugia malayi Dopamine receptor protein 2 0.0037 0.0075 0.0218
Trypanosoma cruzi cyclin, putative 0.0102 0.0286 0.1949
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Schistosoma mansoni hypothetical protein 0.0024 0.0029 0.0029
Echinococcus multilocularis pyruvate kinase 0.0025 0.0034 0.0034
Brugia malayi putative neuropeptide receptor NPR1 0.0037 0.0075 0.0218
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0086 0.0234 0.172
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0026 0.0036 0.0155
Entamoeba histolytica acyl-coA synthetase, putative 0.0054 0.013 0.1682
Mycobacterium leprae conserved hypothetical protein 0.002 0.0018 0.0296
Onchocerca volvulus 0.0035 0.0068 0.0294
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0175 0.0527 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0132 0.0132
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0024 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.008 0.0216 0.0628
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0065 0.0164 0.2127
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0004 0.0016
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.002 0.0018 0.0116
Trypanosoma cruzi pyruvate kinase 2, putative 0.0025 0.0034 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0037 0.0251
Echinococcus granulosus beta-adrenergic receptor kinase 0.0109 0.0308 0.0308
Echinococcus granulosus tumor protein p63 0.0222 0.068 0.068
Schistosoma mansoni thyroid hormone receptor 0.0038 0.0077 0.0077
Echinococcus granulosus dro:myosuppressin receptor 0.0037 0.0075 0.0075
Echinococcus granulosus 7TM GPCR rhodopsin 0.0037 0.0075 0.0075
Loa Loa (eye worm) cytochrome P450 0.0015 0.0002 0.0006
Echinococcus granulosus insulin receptor 0.0242 0.0748 0.0748
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0007 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0004 0.0013
Schistosoma mansoni phd/f-box containing protein 0.0048 0.0109 0.0108
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0054 0.013 0.2434
Schistosoma mansoni DNA polymerase eta 0.006 0.0149 0.0149
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0075 0.0075
Echinococcus granulosus phd:f box containing protein 0.0048 0.0109 0.0108
Echinococcus multilocularis 0.0225 0.0689 0.0689
Entamoeba histolytica protein kinase, putative 0.0015 0.0000078307 0.00000016106
Leishmania major cyclin 0.0102 0.0286 0.1949
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.0077 0.0334
Echinococcus granulosus cyclins 0.0042 0.0091 0.0091
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0016 0.0004 0.0041
Schistosoma mansoni hypothetical protein 0.0023 0.0029 0.0029
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0065 0.0441
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0103 0.0289 0.1969
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni hypothetical protein 0.0433 0.1374 0.1374
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0018 0.0053
Leishmania major phosphopantetheinyl transferase-like protein 0.002 0.0018 0.0121
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Echinococcus multilocularis sex peptide receptor 0.0037 0.0075 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.013
Loa Loa (eye worm) transcription factor SMAD2 0.0177 0.0534 0.1553
Entamoeba histolytica cyclin family protein 0.0042 0.0091 0.1183
Leishmania major trypanothione reductase 0.0034 0.0063 0.043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0077 0.0225
Echinococcus multilocularis muscleblind protein 0.0373 0.1176 0.1176
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.02 0.061 0.061
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0077 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.0077 0.0225
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0496
Brugia malayi latrophilin 2 splice variant baaae 0.0051 0.0119 0.0346
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0178 0.0537 0.1561
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0075 0.0075
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.0077 0.0077
Echinococcus granulosus cyclins 0.0042 0.0091 0.0091
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0024 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.0077 0.0225
Echinococcus granulosus dna polymerase kappa 0.0037 0.0075 0.0075
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0075 0.0075
Brugia malayi photoreceptor-specific nuclear receptor 0.0038 0.0077 0.0225
Brugia malayi RNA, U transporter 1 0.0111 0.0317 0.0922
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0032 0.0138
Echinococcus granulosus alkaline phosphatase 0.0121 0.035 0.035
Echinococcus multilocularis high affinity choline transporter 1 0.031 0.0968 0.0968
Onchocerca volvulus 0.0037 0.0075 0.0324
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0416 0.0415
Giardia lamblia G2/mitotic-specific cyclin B 0.0102 0.0286 0.3704
Echinococcus granulosus chromobox protein 1 0.0042 0.0091 0.0091
Leishmania major hypothetical protein, conserved 0.0048 0.0109 0.0739
Loa Loa (eye worm) TK/INSR protein kinase 0.0242 0.0748 0.2173
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0067 0.0171 0.0496
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.0077 0.0225
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0016 0.0004 0.0041
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0077 0.0205 0.151
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0004 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0077 0.0225
Onchocerca volvulus Alhambra homolog 0.0071 0.0187 0.0807
Plasmodium vivax acyl-CoA synthetase, putative 0.004 0.0085 0.1613
Echinococcus multilocularis RUN 0.0035 0.0068 0.0068
Schistosoma mansoni rab6-interacting 0.0035 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.004 0.0085 0.0247
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0037 0.0075 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0722 0.232 0.232
Plasmodium falciparum phd finger protein, putative 0.0071 0.0187 0.3541
Brugia malayi beta-lactamase family protein 0.0067 0.0171 0.0496
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0016 0.0004 0.0056
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0122 0.0353 0.2607
Brugia malayi Protein kinase domain containing protein 0.0015 0.0000078307 0.000000036158
Brugia malayi nuclear receptor NHR-88 0.0018 0.0011 0.0033
Echinococcus granulosus intestinal type alkaline phosphatase 0.0121 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0032
Trypanosoma cruzi ISWI complex protein 0.0022 0.0026 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0037 0.0075 0.0218
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Schistosoma mansoni polycystin 1-related 0.0035 0.0068 0.0068
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0002 0.0036
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0037 0.0075 0.0511
Leishmania major hypothetical protein, conserved 0.0067 0.0171 0.1161
Schistosoma mansoni rab6-interacting 0.0035 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0396
Echinococcus granulosus dna polymerase eta 0.006 0.0149 0.0149
Echinococcus granulosus G protein coupled receptor 139 0.0037 0.0075 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Brugia malayi jmjC domain containing protein 0.0048 0.0109 0.0315
Schistosoma mansoni tyrosine kinase 0.0015 0.0000078307 0.000000012436
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Schistosoma mansoni cyclin B3 0.0042 0.0091 0.0091
Brugia malayi nuclear hormone receptor 0.0038 0.0077 0.0225
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0034 0.0064 0.0064
Trichomonas vaginalis set domain proteins, putative 0.072 0.2313 1
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0121 0.035 0.035
Mycobacterium ulcerans lipase LipD 0.0067 0.0171 0.2249
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0034 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.03 0.1298
Trypanosoma brucei protein kinase, putative 0.0017 0.0008 0.0057
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0335 0.0335
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Brugia malayi larval opioid receptor 0.0037 0.0075 0.0218
Echinococcus granulosus lipoxygenase domain containing protein 0.0035 0.0068 0.0068
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0075 0.0075
Schistosoma mansoni cyclin B 0.0102 0.0286 0.0286
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0037 0.0075 0.0075
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0002 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0037 0.0251
Trypanosoma cruzi cruzipain precursor, putative 0.0042 0.009 0.061
Loa Loa (eye worm) hypothetical protein 0.0054 0.013 0.0378
Onchocerca volvulus 0.0037 0.0075 0.0324
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0079 0.0213 0.0213
Echinococcus granulosus pyruvate kinase 0.0025 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0102 0.0286 0.0832
Schistosoma mansoni sodium/solute symporter 0.0034 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus multilocularis orexin receptor type 2 0.0037 0.0075 0.0075
Schistosoma mansoni amine GPCR 0.0037 0.0075 0.0075
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Brugia malayi jmjC domain containing protein 0.0048 0.0109 0.0315
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.004 0.0085 0.0615
Leishmania major telomerase reverse transcriptase, putative 0.0103 0.0289 0.1969
Giardia lamblia Hypothetical protein 0.0042 0.0091 0.1183
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0004 0.0029
Brugia malayi Regulator of G protein signaling domain containing protein 0.0106 0.03 0.0872
Echinococcus granulosus jumonji domain containing 1A 0.0048 0.0109 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Entamoeba histolytica hypothetical protein 0.0032 0.0056 0.0727
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0027 0.0078
Loa Loa (eye worm) melatonin receptor type 1A 0.0037 0.0075 0.0218
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0121 0.035 0.035
Brugia malayi Zinc finger, C2H2 type family protein 0.0068 0.0177 0.0513
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.011 0.075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.0537 0.0537
Brugia malayi PHD-finger family protein 0.004 0.0084 0.0243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.0077 0.0225
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.009 0.061
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0308 0.0308
Onchocerca volvulus 0.0037 0.0075 0.0324
Echinococcus multilocularis lysosomal alpha glucosidase 0.0217 0.0664 0.0664
Loa Loa (eye worm) hypothetical protein 0.0054 0.013 0.0378
Schistosoma mansoni neuropeptide receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0373 0.1176 0.342
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0175 0.0527 0.3589
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0034 0.0064 0.1053
Brugia malayi hypothetical protein 0.0315 0.0985 0.2863
Trypanosoma brucei glucosidase, putative 0.0048 0.011 0.075
Brugia malayi RNA recognition motif domain containing protein 0.0141 0.0416 0.1208
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0087
Onchocerca volvulus Neuropeptide F receptor homolog 0.0037 0.0075 0.0324
Echinococcus granulosus neuropeptide receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0037 0.0075 0.0218
Loa Loa (eye worm) PHD-finger family protein 0.0071 0.0187 0.0542
Schistosoma mansoni neuropeptide f receptor 76f 0.0037 0.0075 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0171 0.1161
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0016 0.0004 0.0016
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0254 0.0254
Brugia malayi tailless protein 0.0018 0.0011 0.0033
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0037 0.0075 0.0075
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0075 0.0972
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.0077 0.0077
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0067 0.0171 0.0496
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0002 0.0015
Toxoplasma gondii pyruvate kinase PyK1 0.0025 0.0034 0.0553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0177 0.0764
Echinococcus granulosus expressed protein 0.0106 0.03 0.03
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0078 0.0562
Loa Loa (eye worm) hypothetical protein 0.004 0.0085 0.0247
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0011 0.0075
Schistosoma mansoni amine GPCR 0.0037 0.0075 0.0075
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0034 0.0064 0.0064
Echinococcus granulosus neuropeptide FF receptor 2 0.0037 0.0075 0.0075
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Echinococcus granulosus dnaJ subfamily B 0.0894 0.2886 0.2886
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0014 0.0014
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0018 0.0018
Brugia malayi AKH receptor 0.0037 0.0075 0.0218
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0075 0.0075
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0048 0.011 0.1805
Entamoeba histolytica ankyrin repeat protein 0.0015 0.0000078307 0.00000016106
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0037 0.0251
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0024 0.0032 0.0032
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0037 0.0075 0.0075
Echinococcus granulosus RUN 0.0035 0.0068 0.0068
Echinococcus granulosus regulator of G protein signaling 7 0.0106 0.03 0.03
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0024 0.0032 0.0032
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0037 0.0072 0.0072
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.002 0.0018 0.0291
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus neutral alpha glucosidase AB 0.0048 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0142 0.042 0.0419
Echinococcus multilocularis cyclin B 0.0102 0.0286 0.0286
Onchocerca volvulus 0.0037 0.0075 0.0324
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0122 0.0353 0.6681
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.0077 0.0334
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0087 0.0236 0.448
Mycobacterium ulcerans aldehyde dehydrogenase 0.02 0.061 0.8118
Brugia malayi Tachykinin-like peptides receptor 99D 0.0037 0.0075 0.0218
Schistosoma mansoni coup transcription factor 0.0038 0.0077 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0036 0.0156
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0014 0.0014
Brugia malayi conserved hypotetical protein 0.0018 0.0011 0.0033
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0025 0.0034 0.0234
Trypanosoma brucei unspecified product 0.0026 0.0037 0.0251
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Brugia malayi Cytochrome P450 family protein 0.0015 0.0002 0.0006
Echinococcus granulosus jumonji domain containing protein 0.0099 0.0278 0.0278
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Trichomonas vaginalis antibiotic synthetase, putative 0.0016 0.0004 0.0019
Schistosoma mansoni hypothetical protein 0.0894 0.2886 0.2886
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0175 0.0527 0.1532
Mycobacterium tuberculosis Conserved hypothetical protein 0.0243 0.075 0.5564
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0022 0.0094
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0034 0.0098
Loa Loa (eye worm) TAR-binding protein 0.0141 0.0416 0.1208
Echinococcus granulosus pyruvate kinase 0.0025 0.0034 0.0034
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Echinococcus multilocularis bloom syndrome protein 0.0018 0.0012 0.0012
Schistosoma mansoni alpha-glucosidase 0.0187 0.0565 0.0565
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0087 0.0236 0.3872
Loa Loa (eye worm) hypothetical protein 0.0034 0.0064 0.0185
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.0077 0.0077
Echinococcus multilocularis snurportin 1 0.0417 0.1322 0.1322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Trichomonas vaginalis cyclin D, putative 0.0042 0.0091 0.0395
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Echinococcus multilocularis expressed conserved protein 0.0061 0.0151 0.0151
Brugia malayi Pyruvate kinase, muscle isozyme 0.0025 0.0034 0.0098
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.011 0.0476
Onchocerca volvulus 0.0023 0.0027 0.0117
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0048 0.0109 0.0315
Schistosoma mansoni tyrosine kinase 0.0386 0.1218 0.1218
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0002 0.0015
Brugia malayi G-protein coupled receptor 0.0037 0.0075 0.0218
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0016 0.0004 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0011 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0067 0.0171 0.3207
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0011 0.0011
Leishmania major glycosyl hydrolase-like protein 0.0018 0.0011 0.0075
Schistosoma mansoni tyrosine kinase 0.0242 0.0748 0.0748
Echinococcus granulosus sodium:myo inositol cotransporter 0.0034 0.0064 0.0064
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0075 0.0218
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0016 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0117 0.0335 0.0975
Schistosoma mansoni patched 1 0.0028 0.0043 0.0043
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0175 0.0527 0.3589
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.0077 0.0225
Echinococcus granulosus GPCR family 2 0.0024 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0053
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0016 0.0005 0.009
Brugia malayi hypothetical protein 0.0106 0.03 0.0872
Echinococcus granulosus activin receptor type 0.0017 0.0008 0.0008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0075 0.0075
Schistosoma mansoni tyrosine kinase 0.0736 0.2368 0.2368
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0008 0.0057
Loa Loa (eye worm) hypothetical protein 0.004 0.0085 0.0247
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0022 0.0094
Schistosoma mansoni amine GPCR 0.0037 0.0075 0.0075
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0075 0.0075
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0067 0.0171 0.1251
Schistosoma mansoni jumonji domain containing protein 0.0278 0.0865 0.0865
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0037 0.0075 0.0075
Schistosoma mansoni cellular tumor antigen P53 0.0032 0.0059 0.0059
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.0077 0.0077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0022 0.0094
Loa Loa (eye worm) hypothetical protein 0.0707 0.2272 0.6606
Echinococcus granulosus zinc finger protein 0.0032 0.0058 0.0058
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0011 0.0011
Schistosoma mansoni high-affinity choline transporter 0.031 0.0968 0.0968
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Brugia malayi Cyclin, N-terminal domain containing protein 0.0102 0.0286 0.0832
Onchocerca volvulus 0.072 0.2313 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0077 0.0225
Echinococcus multilocularis lysine specific demethylase 6a 0.0048 0.0109 0.0108
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0018 0.0018
Brugia malayi jmjC domain containing protein 0.0326 0.1023 0.2973
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0219 0.0669 0.4561
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0052 0.0122 0.2008
Mycobacterium ulcerans esterase/lipase LipP 0.0067 0.0171 0.2249
Trichomonas vaginalis DNA helicase recq, putative 0.0018 0.0012 0.0052
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Brugia malayi Bromodomain containing protein 0.0075 0.0198 0.0575
Brugia malayi hypothetical protein 0.002 0.0018 0.0053
Trypanosoma brucei glycosyl hydrolase-like protein 0.0018 0.0011 0.0075
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0079 0.0213 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0011 0.0033
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0016 0.0004 0.0029
Toxoplasma gondii propionate-CoA ligase 0.0016 0.0004 0.0071
Brugia malayi Doublecortin family protein 0.0035 0.0068 0.0198
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1063 0.3439 1
Onchocerca volvulus 0.0016 0.0004 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.011 0.0476
Brugia malayi CHE-14 protein 0.0028 0.0043 0.0126
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1063 0.3439 1
Onchocerca volvulus 0.0067 0.0171 0.0737
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0013
Echinococcus multilocularis muscleblind protein 1 0.0373 0.1176 0.1176
Schistosoma mansoni hypothetical protein 0.0194 0.059 0.059
Echinococcus multilocularis peregrin 0.0075 0.0198 0.0198
Trichomonas vaginalis cyclins, putative 0.0042 0.0091 0.0395
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0036 0.0156
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0462 0.1468 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.0077 0.0225
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.013 0.095
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0075 0.0075
Trypanosoma brucei importin beta-1 subunit, putative 0.0039 0.008 0.0548
Mycobacterium leprae Probable lipase LipE 0.0067 0.0171 0.3207
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0171 0.017
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0037 0.0075 0.0075
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0048 0.011 0.1425
Entamoeba histolytica cyclin family protein 0.0042 0.0091 0.1183
Trypanosoma brucei unspecified product 0.0026 0.0037 0.0251
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0016 0.0004 0.0029
Loa Loa (eye worm) RecQ helicase 0.0018 0.0012 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Schistosoma mansoni tyrosine kinase 0.0242 0.0748 0.0748
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0242 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.0315 0.0985 0.2863
Echinococcus granulosus cpg binding protein 0.0069 0.0179 0.0179
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0028 0.0043 0.03
Leishmania major cathepsin L-like protease 0.0042 0.009 0.061
Leishmania major cathepsin L-like protease 0.0042 0.009 0.061
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0098
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0075 0.0075
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0091 0.0394
Echinococcus multilocularis solute carrier family 5 0.0034 0.0064 0.0064
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0053 0.0125 0.0125
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0048 0.0109 0.0739
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0075 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0018 0.0121
Entamoeba histolytica cyclin, putative 0.0102 0.0286 0.3704
Echinococcus granulosus g-protein coupled receptor 0.0037 0.0075 0.0075
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0034 0.0146
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0016 0.0004 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0004 0.0013
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0011 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0022 0.0094
Plasmodium falciparum JmjC domain-containing protein, putative 0.0048 0.0109 0.2059
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0048 0.0109 0.0108
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.0077 0.0077
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.0077 0.0077
Echinococcus granulosus JmjC domain containing protein 4 0.0048 0.0109 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Trypanosoma brucei mitotic cyclin 6 0.0102 0.0286 0.1949
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0063 0.043
Giardia lamblia PHD finger protein 15 0.0071 0.0187 0.2416
Leishmania major DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Toxoplasma gondii HEAT repeat-containing protein 0.0039 0.008 0.1319
Echinococcus multilocularis PHD finger protein rhinoceros 0.0071 0.0187 0.0187
Mycobacterium ulcerans acetyl-CoA synthetase 0.0016 0.0004 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0011 0.0048
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 3 0.0106 0.03 0.03
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.013 0.1707
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0065 0.0165 0.1126
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0075 0.0511
Loa Loa (eye worm) hypothetical protein 0.0059 0.0147 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0087 0.0236 0.3057
Echinococcus granulosus cyclin b3 0.0042 0.0091 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.0077 0.0225
Schistosoma mansoni inositol transporter 0.0034 0.0064 0.0064
Echinococcus multilocularis protein patched 0.0028 0.0043 0.0043
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0075 0.0075
Onchocerca volvulus 0.0019 0.0013 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0075 0.0972
Brugia malayi jmjC domain containing protein 0.0185 0.0559 0.1626
Loa Loa (eye worm) TYRA-2 protein 0.0037 0.0075 0.0218
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0075 0.0075
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0042 0.0091 0.0091
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0024 0.003 0.013
Echinococcus multilocularis microtubule associated protein 2 0.3063 1 1
Entamoeba histolytica cyclin, putative 0.0042 0.0091 0.1183
Brugia malayi Bromodomain containing protein 0.0056 0.0136 0.0395
Brugia malayi nuclear hormone receptor 0.0018 0.0011 0.0033
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.006 0.041
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0075 0.0324
Loa Loa (eye worm) hypothetical protein 0.0106 0.03 0.0872
Echinococcus multilocularis dnaJ subfamily B 0.0894 0.2886 0.2886
Echinococcus granulosus regulator of G protein signaling 3 0.0106 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0051 0.0119 0.0346
Brugia malayi beta-lactamase family protein 0.0067 0.0171 0.0496
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0014 0.0014
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0075 0.0075
Brugia malayi hypothetical protein 0.0035 0.0068 0.0198
Echinococcus multilocularis serotonin receptor 0.0037 0.0075 0.0075
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0016 0.0004 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0011 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0416 0.0415
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0075 0.0075
Plasmodium falciparum acyl-CoA synthetase 0.004 0.0085 0.1613
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus epidermal growth factor receptor 0.0736 0.2368 0.2368
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.0537 0.0537
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Plasmodium vivax acetyl-CoA synthetase, putative 0.0016 0.0004 0.0082
Loa Loa (eye worm) hypothetical protein 0.008 0.0216 0.0628
Echinococcus multilocularis G-protein coupled receptor, putative 0.0037 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0417 0.1322 0.1322
Brugia malayi regulator of G-protein signaling egl-10 0.0106 0.03 0.0872
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0023 0.0029 0.0196
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0054 0.013 0.095
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0122 0.0353 0.4685
Mycobacterium ulcerans aldehyde dehydrogenase 0.02 0.061 0.8118
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0016 0.0004 0.0029
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0037 0.0075 0.0218
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0011 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.03 0.1298
Echinococcus granulosus g protein coupled receptor 0.0037 0.0075 0.0075
Echinococcus granulosus hypothetical protein 0.0037 0.0075 0.0075
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0074 0.0196 0.0571
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0002 0.0006
Echinococcus granulosus survival motor neuron protein 1 0.0315 0.0985 0.0985
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0106 0.03 0.0872
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Brugia malayi Regulator of G protein signaling domain containing protein 0.0106 0.03 0.0872
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0017 0.0008 0.0008
Brugia malayi Cytochrome P450 family protein 0.0015 0.0002 0.0006
Echinococcus granulosus snurportin 1 0.0417 0.1322 0.1322
Brugia malayi Telomerase reverse transcriptase 0.0273 0.0849 0.2468
Onchocerca volvulus 0.0032 0.0059 0.0254
Loa Loa (eye worm) hypothetical protein 0.0103 0.0292 0.0848
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0004 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.03 0.1298
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0132 0.1731
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0121 0.035 0.035
Schistosoma mansoni hypothetical protein 0.003 0.0051 0.0051
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0065 0.0165 0.1126
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0037 0.0075 0.0075
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0537 0.0537
Brugia malayi nuclear receptor NHR-88 0.0038 0.0077 0.0225
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.011 0.0476
Echinococcus multilocularis protein dispatched 1 0.0032 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0707 0.2272 0.6606
Loa Loa (eye worm) heterochromatin protein 1 0.0042 0.0091 0.0265
Onchocerca volvulus 0.0016 0.0004 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.013
Brugia malayi Dopamine receptor 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0035 0.0068 0.0198
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0126
Loa Loa (eye worm) hypothetical protein 0.0054 0.013 0.0378
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0024 0.0029 0.0086
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0037 0.0075 0.0218
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0037 0.0075 0.0075
Plasmodium falciparum telomerase reverse transcriptase 0.0103 0.0289 0.5487
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0048 0.0109 0.178
Schistosoma mansoni cytochrome P450 0.0015 0.0002 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0074 0.0196 0.0571
Echinococcus granulosus chromobox protein 1 0.0042 0.0091 0.0091
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0037 0.0075 0.0541
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0022 0.0094
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0068 0.0177 0.1203
Schistosoma mansoni zinc finger protein 0.0018 0.0011 0.0011
Onchocerca volvulus 0.0037 0.0075 0.0324
Schistosoma mansoni microtubule-associated protein tau 0.3063 1 1
Brugia malayi RE15519p 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.006 0.0149 0.0434
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0171 0.1161
Trypanosoma brucei importin beta-1 subunit, putative 0.0039 0.008 0.0548
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0004 0.0013
Echinococcus multilocularis somatostatin receptor 0.0037 0.0075 0.0075
Onchocerca volvulus 0.0037 0.0075 0.0324
Leishmania major pyruvate kinase 0.0025 0.0034 0.0229
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Echinococcus granulosus Regulator of G protein signaling 20 0.0106 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0254 0.0254
Mycobacterium ulcerans aldehyde dehydrogenase 0.02 0.061 0.8118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0137 0.0399
Onchocerca volvulus 0.0037 0.0075 0.0324
Echinococcus granulosus fmrfamide receptor 0.0037 0.0075 0.0075
Trichomonas vaginalis pyruvate kinase, putative 0.0025 0.0034 0.0146
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0171 0.0737
Trichomonas vaginalis cyclin B, putative 0.0042 0.0091 0.0395
Plasmodium vivax glutathione reductase, putative 0.0034 0.0063 0.1197
Brugia malayi sulfakinin receptor protein 0.0037 0.0075 0.0218
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0037 0.0075 0.0075
Leishmania major importin beta-1 subunit, putative 0.0032 0.0056 0.0383
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.0077 0.0077
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0091 0.0251 0.025
Brugia malayi ecdysteroid receptor 0.0038 0.0077 0.0225
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0004 0.0013
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0037 0.0075 0.0075
Echinococcus multilocularis GPCR, family 2 0.0024 0.0029 0.0029
Trichomonas vaginalis cyclins, putative 0.0102 0.0286 0.1237
Schistosoma mansoni protein phosphatase 2C 0.0048 0.0109 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Brugia malayi TAR-binding protein 0.0141 0.0416 0.1208
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.004
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0075 0.0075
Leishmania major pyruvate kinase 0.0025 0.0034 0.0229
Brugia malayi Pre-SET motif family protein 0.0632 0.2027 0.5892
Echinococcus granulosus histone lysine methyltransferase setb 0.0117 0.0335 0.0335
Echinococcus multilocularis tumor protein p63 0.0222 0.068 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0007 0.0032
Plasmodium falciparum importin beta, putative 0.0039 0.008 0.1527
Schistosoma mansoni growth hormone secretagogue receptor 0.0037 0.0075 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.0077 0.0225
Brugia malayi beta-lactamase 0.0067 0.0171 0.0496
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0075 0.0075
Brugia malayi nuclear receptor NHR-67 0.0018 0.0011 0.0033
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0171 0.0737
Brugia malayi nuclear receptor RXR 0.0018 0.0011 0.0033
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0016 0.0004 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Echinococcus multilocularis axis inhibition protein axin 0.0106 0.03 0.03
Echinococcus multilocularis tar DNA binding protein 0.0141 0.0416 0.0415
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0079 0.0213 0.145
Trichomonas vaginalis sucrase-isomaltase, putative 0.0048 0.011 0.0476
Trichomonas vaginalis penicillin-binding protein, putative 0.0067 0.0171 0.0737
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.0077 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0053
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0099 0.0277 0.0277
Echinococcus multilocularis chromobox protein 1 0.0042 0.0091 0.0091
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0016 0.0004 0.0029
Loa Loa (eye worm) oxidoreductase 0.0016 0.0004 0.0013
Echinococcus granulosus sodium:glucose cotransporter 2 0.0034 0.0064 0.0064
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0086 0.0234 0.4408
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0067 0.0171 0.017
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0072 0.0187 0.0808
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.0077 0.0225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Brugia malayi nuclear receptor RXR 0.002 0.0018 0.0053
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0011 0.0033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0075 0.0075
Schistosoma mansoni biogenic amine receptor 0.0037 0.0075 0.0075
Echinococcus granulosus bloom syndrome protein 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0496
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0117 0.0335 0.0335
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0087 0.0236 0.1021
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.03 0.1298
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Loa Loa (eye worm) beta-lactamase 0.0067 0.0171 0.0496
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0015 0.0000078307 0.000000036158
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0149 0.1018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0092
Echinococcus multilocularis expressed protein 0.0106 0.03 0.03
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0028 0.0043 0.0126
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0024 0.0029 0.0029
Onchocerca volvulus 0.0034 0.0064 0.0278
Brugia malayi neuropeptide F receptor 0.0037 0.0075 0.0218
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0109 0.0315
Schistosoma mansoni protein kinase 0.0017 0.0008 0.0008
Brugia malayi Glycosyl hydrolases family 31 protein 0.0217 0.0664 0.193
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0075 0.0075
Echinococcus granulosus X box binding protein 1 0.0194 0.059 0.059
Schistosoma mansoni regulator of G protein signaling 0.0106 0.03 0.03
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0024 0.0032 0.0032
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0075 0.0075
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0149 0.0434
Schistosoma mansoni hypothetical protein 0.0433 0.1374 0.1374
Loa Loa (eye worm) hypothetical protein 0.0034 0.0064 0.0187
Echinococcus granulosus lysine specific demethylase 5A 0.0185 0.0559 0.0559
Loa Loa (eye worm) hypothetical protein 0.0106 0.03 0.0872
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0034 0.0146
Schistosoma mansoni hypothetical protein 0.0064 0.0163 0.0163
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0238 0.0238
Echinococcus granulosus tyrosine protein kinase Lyn 0.0017 0.0008 0.0008
Trichomonas vaginalis cyclins, putative 0.007 0.0181 0.0781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.025 0.0772 0.3339
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Trichomonas vaginalis cyclins, putative 0.0102 0.0286 0.1237
Brugia malayi Niemann-Pick C1 protein precursor 0.0065 0.0164 0.0478
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0016 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.004 0.0085 0.0247
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0177 0.0764
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.002 0.0018 0.0337
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0011 0.0048
Echinococcus granulosus Niemann Pick C1 protein 0.0092 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Leishmania major alpha glucosidase II subunit, putative 0.0048 0.011 0.075
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0175 0.0527 0.3589
Brugia malayi G protein-coupled receptor F59B2.13 0.0037 0.0075 0.0218
Trypanosoma brucei telomerase reverse transcriptase 0.0103 0.0289 0.1969
Loa Loa (eye worm) hypothetical protein 0.0373 0.1176 0.342
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0175 0.0527 0.1532
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0032 0.0217
Schistosoma mansoni myosin xvIII 0.0037 0.0075 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.0067 0.0171 0.017
Schistosoma mansoni protein kinase 0.0017 0.0008 0.0008
Echinococcus granulosus high affinity choline transporter 1 0.031 0.0968 0.0968
Brugia malayi Calcitonin receptor-like protein seb-1 0.0074 0.0196 0.0571
Loa Loa (eye worm) cyclin domain-containing protein 0.0042 0.0091 0.0266
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0053
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0075 0.0324
Brugia malayi hypothetical protein 0.0018 0.0011 0.0033
Echinococcus granulosus alpha 1A adrenergic receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0037 0.0075 0.0218
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0106 0.03 0.0872
Brugia malayi hypothetical protein 0.0142 0.042 0.122
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.013 0.0885
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0037 0.0075 0.0218
Entamoeba histolytica protein kinase, putative 0.0015 0.0000078307 0.00000016106
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0075 0.0218
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0038 0.0077 0.0077
Onchocerca volvulus 0.0037 0.0075 0.0324
Entamoeba histolytica protein kinase domain containing protein 0.0017 0.0008 0.0108
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0066 0.0168 0.0168
Brugia malayi GH02984p 0.031 0.0968 0.2815
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0037 0.0075 0.0075
Plasmodium falciparum dihydroorotate dehydrogenase 0.0175 0.0527 1
Schistosoma mansoni lipoxygenase 0.0035 0.0068 0.0068
Mycobacterium tuberculosis Conserved protein 0.0067 0.0171 0.1251
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0004 0.0029
Trichomonas vaginalis maltase-glucoamylase, putative 0.0048 0.011 0.0476
Echinococcus granulosus FTZ F1 alpha 0.0038 0.0077 0.0077
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0024 0.0029 0.0029
Loa Loa (eye worm) thioredoxin reductase 0.0034 0.0063 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.03 0.1298
Schistosoma mansoni neuropeptide receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.071 0.2281 0.228
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0054 0.013 0.1707
Loa Loa (eye worm) hypothetical protein 0.0048 0.0109 0.0315
Echinococcus multilocularis Niemann Pick C1 protein 0.0065 0.0164 0.0164
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0175 0.0527 0.3901
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0037 0.0075 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0018 0.0011 0.0032
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0234
Trichomonas vaginalis pyruvate kinase, putative 0.0025 0.0034 0.0146
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Brugia malayi chromobox protein homolog 3 0.0024 0.003 0.0087
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0079 0.0213 0.2815
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0034 0.0146
Schistosoma mansoni nuclear receptor 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0147 0.0435 0.1264
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0078 0.0562
Onchocerca volvulus 0.0125 0.0364 0.1572
Echinococcus multilocularis chromobox protein 1 0.0042 0.0091 0.0091
Brugia malayi cytochrome P450 0.0015 0.0002 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Echinococcus multilocularis L aminoadipate semialdehyde 0.0071 0.0185 0.0185
Echinococcus granulosus tyrosine protein kinase shark 0.0015 0.0000078307 0.000000012436
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0032 0.0412
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0109 0.0315
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0077 0.0205 0.151
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0187 0.3541
Schistosoma mansoni z-protein (S1r protein) 0.0106 0.03 0.03
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0037 0.0075 0.0218
Brugia malayi AF-10 protein 0.0023 0.0029 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0004 0.0029
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0011 0.0033
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.002 0.0018 0.0291
Echinococcus granulosus 7tm_1 domain containing protein 0.0037 0.0075 0.0075
Brugia malayi jmjC domain containing protein 0.0048 0.0109 0.0315
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.002 0.0018 0.0337
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0016 0.0004 0.0029
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0011 0.0011
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0017 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0957 0.3091 0.8989
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.009 0.061
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0077 0.0205 0.151
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0026 0.0039 0.0262
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0002 0.0002
Echinococcus multilocularis activin receptor type 0.0017 0.0008 0.0008
Toxoplasma gondii thioredoxin reductase 0.0034 0.0063 0.1035
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0175 0.0527 0.7011
Echinococcus multilocularis cyclin b3 0.0042 0.0091 0.0091
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0048 0.011 0.1425
Echinococcus granulosus Protein patched homolog 1 0.0028 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni hypothetical protein 0.0024 0.0029 0.0029
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0957 0.3091 0.3091
Trichomonas vaginalis D-aminoacylase, putative 0.0067 0.0171 0.0737
Echinococcus multilocularis survival motor neuron protein 1 0.0315 0.0985 0.0985
Echinococcus granulosus ubiquitin specific protease 41 0.0024 0.0032 0.0032
Brugia malayi Heterochromatin protein 1 0.0042 0.0091 0.0265
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0016 0.0004 0.0082
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0038 0.0077 0.0077
Brugia malayi CXXC zinc finger family protein 0.0063 0.0158 0.046
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0037 0.0075 0.0218
Trichomonas vaginalis importin beta-1, putative 0.0032 0.0056 0.0243
Plasmodium falciparum thioredoxin reductase 0.0034 0.0063 0.1197
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0011 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0067 0.0171 0.1161
Onchocerca volvulus 0.0064 0.0163 0.0704
Echinococcus multilocularis g-protein coupled receptor 0.0037 0.0075 0.0075
Brugia malayi glutathione reductase 0.0034 0.0063 0.0183
Schistosoma mansoni hypothetical protein 0.0063 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0071 0.0187 0.0542
Mycobacterium tuberculosis Conserved protein 0.0067 0.0171 0.1251
Schistosoma mansoni chromobox protein 0.0042 0.0091 0.0091
Mycobacterium tuberculosis Probable reductase 0.0077 0.0205 0.151
Schistosoma mansoni regulator of G protein signaling 0.0106 0.03 0.03
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0087 0.0236 0.448
Brugia malayi neuropeptide F receptor 0.0037 0.0075 0.0218
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Schistosoma mansoni cpg binding protein 0.0063 0.0158 0.0158
Toxoplasma gondii PHD-finger domain-containing protein 0.0023 0.0029 0.0472
Schistosoma mansoni pyruvate kinase 0.0025 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Trichomonas vaginalis esterase, putative 0.0067 0.0171 0.0737
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0109 0.0739
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0326 0.1023 0.1022
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0037 0.0075 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0462 0.1468 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0109 0.0308 0.0897
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1137 0.3682 0.3682
Echinococcus granulosus axis inhibition protein axin 0.0106 0.03 0.03
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0016 0.0004 0.0029
Giardia lamblia Kinase, NEK 0.0015 0.0000078307 0.00000016106
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0099 0.0277 0.0277
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis zinc finger protein 0.0032 0.0058 0.0058
Leishmania major protein kinase, putative 0.0017 0.0008 0.0057
Schistosoma mansoni tyrosine kinase 0.0386 0.1218 0.1218
Trypanosoma cruzi CYC2-like cyclin, putative 0.0102 0.0286 0.1949
Echinococcus granulosus lysosomal alpha glucosidase 0.0217 0.0664 0.0664
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0132 0.0132
Schistosoma mansoni amine GPCR 0.0037 0.0075 0.0075
Brugia malayi Pre-SET motif family protein 0.0092 0.0254 0.0737
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0004 0.0016
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0072 0.0187 0.0187
Schistosoma mansoni inositol transporter 0.0034 0.0064 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Echinococcus multilocularis alkaline phosphatase 0.0121 0.035 0.035
Echinococcus granulosus muscleblind protein 0.0373 0.1176 0.1176
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Schistosoma mansoni thyroid hormone receptor 0.0038 0.0077 0.0077
Echinococcus granulosus cyclins 0.0042 0.0091 0.0091
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0048 0.0109 0.0317
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0132 0.1731
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0142 0.042 0.0419
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0075 0.0075
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0326 0.1023 0.1022
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0065 0.1062
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0075 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0075 0.0075
Mycobacterium ulcerans pyruvate kinase 0.0025 0.0034 0.0421
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0034 0.0064 0.0064
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0022 0.0094
Trichomonas vaginalis cyclin A, putative 0.0102 0.0286 0.1237
Brugia malayi AMP-binding enzyme family protein 0.0054 0.013 0.0378
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.0077 0.0077
Echinococcus granulosus cyclins 0.0042 0.0091 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0075 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0048 0.011 0.032
Echinococcus granulosus regulator of G protein signaling 7 0.0106 0.03 0.03
Schistosoma mansoni alpha glucosidase 0.0048 0.011 0.011
Brugia malayi ORL1-like opioid receptor 0.0037 0.0075 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0075 0.0075
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0957 0.3091 0.8989
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0087 0.0236 0.1021
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0024 0.0032 0.0032
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0048 0.0109 0.178
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0011 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0032 0.0056 0.0243
Echinococcus multilocularis cpg binding protein 0.0069 0.0179 0.0179
Schistosoma mansoni acetyl-CoA synthetase 0.0016 0.0004 0.0004
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0016 0.0004 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0018 0.0018
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0037 0.0075 0.0324
Brugia malayi Bromodomain containing protein 0.0113 0.0324 0.0942
Mycobacterium tuberculosis Probable hydrolase 0.0067 0.0171 0.1251
Brugia malayi AMP-binding enzyme family protein 0.0054 0.013 0.0378
Loa Loa (eye worm) RNA binding protein 0.0141 0.0416 0.1208
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0219 0.0669 0.4561
Brugia malayi jmjC domain containing protein 0.0048 0.0109 0.0315
Brugia malayi hypothetical protein 0.0037 0.0075 0.0218
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0054 0.0129 0.0129
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0075 0.0075
Echinococcus granulosus Niemann Pick C1 protein 0.0065 0.0164 0.0164
Toxoplasma gondii PHD-finger domain-containing protein 0.0071 0.0187 0.306
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0032 0.0217
Loa Loa (eye worm) hypothetical protein 0.0037 0.0075 0.0218
Schistosoma mansoni importin beta-1 0.0039 0.008 0.008
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0087 0.0236 0.1021
Echinococcus granulosus Polycystic kidney disease protein 0.0035 0.0068 0.0068
Echinococcus multilocularis integrin linked protein kinase 0.0015 0.0000078307 0.000000012436
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0075 0.0511
Leishmania major cathepsin L-like protease 0.0042 0.009 0.061
Echinococcus granulosus regulator of G protein signaling 3 0.0106 0.03 0.03
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0075 0.0075
Trypanosoma cruzi importin beta-1 subunit, putative 0.0032 0.0056 0.0383
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0158 0.046
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0011 0.0033
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0054 0.0129 0.0129
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0002 0.0006
Echinococcus granulosus peptide allatostatin:somatostatin 0.0037 0.0075 0.0075
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0141 0.0416 0.1208
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0106 0.03 0.1298
Onchocerca volvulus Huntingtin homolog 0.008 0.0216 0.0934
Entamoeba histolytica hypothetical protein 0.0106 0.03 0.3886
Brugia malayi PXA domain containing protein 0.0106 0.03 0.0872
Echinococcus multilocularis insulin receptor 0.0242 0.0748 0.0748
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0078 0.0562
Loa Loa (eye worm) hypothetical protein 0.0074 0.0196 0.0571
Schistosoma mansoni hypothetical protein 0.0037 0.0075 0.0075
Onchocerca volvulus 0.0037 0.0075 0.0324
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0416 0.0415
Leishmania major DNA polymerase eta, putative 0.006 0.0149 0.1018
Schistosoma mansoni hypothetical protein 0.0022 0.0026 0.0026
Echinococcus multilocularis neuropeptide FF receptor 2 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.031 0.0968 0.2815
Onchocerca volvulus 0.0063 0.0158 0.0684
Leishmania major dihydroorotate dehydrogenase 0.0175 0.0527 0.3589
Echinococcus multilocularis cyclins 0.0042 0.0091 0.0091
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0091 0.0251 0.025
Echinococcus granulosus methyl CpG binding domain protein 2 0.0025 0.0034 0.0034
Brugia malayi hypothetical protein 0.0035 0.0068 0.0198
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.02 0.061 0.4517
Trichomonas vaginalis maltase-glucoamylase, putative 0.0018 0.0011 0.0048
Brugia malayi Cytochrome P450 family protein 0.0056 0.0137 0.0399
Brugia malayi MH2 domain containing protein 0.0177 0.0534 0.1553
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0086
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0011 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0075 0.0075
Brugia malayi AMP-binding enzyme family protein 0.0054 0.013 0.0378
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0417 0.1322 0.3843
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0225
Brugia malayi Bloom's syndrome protein homolog 0.0018 0.0012 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0079 0.0212 0.1443
Brugia malayi Protein kinase domain containing protein 0.0242 0.0748 0.2173
Mycobacterium tuberculosis Probable esterase LipL 0.0067 0.0171 0.1251
Echinococcus granulosus importin subunit beta 1 0.0039 0.008 0.008
Schistosoma mansoni biogenic amine receptor 0.0037 0.0075 0.0075
Toxoplasma gondii hypothetical protein 0.0032 0.0058 0.0947
Echinococcus multilocularis thyroid hormone receptor alpha 0.0038 0.0077 0.0077
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0067 0.0171 0.1251
Loa Loa (eye worm) hypothetical protein 0.0032 0.0059 0.0171
Brugia malayi Latrophilin receptor protein 2 0.0024 0.0029 0.0086
Echinococcus multilocularis epidermal growth factor receptor 0.0401 0.1266 0.1266
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0142 0.042 0.0419
Schistosoma mansoni regulator of G protein signaling 0.0106 0.03 0.03
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.009 0.061
Entamoeba histolytica hypothetical protein 0.002 0.0018 0.023
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0075 0.0075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0185 0.0559 0.0559
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0032 0.0217
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0011 0.0048
Entamoeba histolytica hypothetical protein 0.0106 0.03 0.3886
Loa Loa (eye worm) MH2 domain-containing protein 0.0177 0.0534 0.1553
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0055 0.0132 0.0132
Loa Loa (eye worm) RGS-3 protein 0.0106 0.03 0.0872
Echinococcus multilocularis tyrosine protein kinase shark 0.0015 0.0000078307 0.000000012436
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0075 0.0511
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0015 0.0000078307 0.000000036158
Echinococcus multilocularis regulator of G protein signaling 3 0.0106 0.03 0.03
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.0537 0.0537

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 8 uM Cytotoxicity measured in human ovarian cell line CH1 using sulforhodamine B (SRB) assay. ChEMBL. 10411488
IC50 (functional) = 8 uM Cytotoxicity measured in human ovarian cell line CH1 using sulforhodamine B (SRB) assay. ChEMBL. 10411488
IC50 (functional) = 9.65 uM Cytotoxicity measured in human ovarian cell line SKOV-3 using sulforhodamine B (SRB) assay. ChEMBL. 10411488
IC50 (functional) = 9.65 uM Cytotoxicity measured in human ovarian cell line SKOV-3 using sulforhodamine B (SRB) assay. ChEMBL. 10411488
IC50 (functional) = 14 uM Cytotoxicity measured in human ovarian cell line A2780 using sulforhodamine B (SRB) assay ChEMBL. 10411488
IC50 (functional) = 14 uM Cytotoxicity measured in human ovarian cell line A2780 using sulforhodamine B (SRB) assay ChEMBL. 10411488
IC50 (binding) = 15.5 uM Inhibitory activity against telomerase ChEMBL. 10411488
IC50 (binding) = 15.5 uM Inhibitory activity against telomerase ChEMBL. 10411488
Inhibition (binding) Inhibitory activity of the compound against taq polymerase at 50 uM; No inhibition ChEMBL. 10411488
Inhibition (binding) Inhibitory activity of the compound against taq polymerase at 10 uM; No inhibition ChEMBL. 10411488
Inhibition (binding) Inhibitory activity of the compound against taq polymerase at 20 uM; No inhibition ChEMBL. 10411488
Inhibition (binding) 0 Inhibitory activity of the compound against taq polymerase at 10 uM; No inhibition ChEMBL. 10411488
Inhibition (binding) 0 Inhibitory activity of the compound against taq polymerase at 20 uM; No inhibition ChEMBL. 10411488
Inhibition (binding) 0 Inhibitory activity of the compound against taq polymerase at 50 uM; No inhibition ChEMBL. 10411488
logIC50 (binding) = 1.19 Inhibition of telomerase (unknown origin) LITERATURE. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 10411488

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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