Detailed information for compound 148507

Basic information

Technical information
  • TDR Targets ID: 148507
  • Name: 6-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]p yrazolo[1,5-a]pyridine
  • MW: 326.823 | Formula: C18H19ClN4
  • H donors: 0 H acceptors: 1 LogP: 3.12 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)N1CCN(CC1)Cc1ccc2n(c1)ncc2
  • InChi: 1S/C18H19ClN4/c19-16-2-5-17(6-3-16)22-11-9-21(10-12-22)13-15-1-4-18-7-8-20-23(18)14-15/h1-8,14H,9-13H2
  • InChiKey: VQWRIGMLIDJHJV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]pyrazolo[1,5-a]pyridine
  • 6-[[4-(4-chlorophenyl)piperazino]methyl]pyrazolo[1,5-a]pyridine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dopamine receptor D4 Starlite/ChEMBL References
Homo sapiens dopamine receptor D3 Starlite/ChEMBL References
Bos taurus Dopamine D1 receptor Starlite/ChEMBL References
Homo sapiens dopamine receptor D2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum 5-hydroxytryptamine receptor, putative Get druggable targets OG5_132667 All targets in OG5_132667
Schistosoma japonicum 5-hydroxytryptamine receptor 1, putative Get druggable targets OG5_132667 All targets in OG5_132667
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein Dopamine D1 receptor   446 aa 370 aa 24.3 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Dopamine D1 receptor   446 aa 371 aa 34.5 %
Schistosoma mansoni biogenic amine (5HT) receptor Dopamine D1 receptor   446 aa 393 aa 32.3 %
Onchocerca volvulus Dopamine D1 receptor   446 aa 359 aa 21.4 %
Brugia malayi hypothetical protein dopamine receptor D3 400 aa 392 aa 19.9 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Dopamine D1 receptor   446 aa 398 aa 33.9 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Dopamine D1 receptor   446 aa 373 aa 27.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae conserved hypothetical protein 0.002 0.0021 0.004
Echinococcus multilocularis regulator of G protein signaling 7 0.0031 0.0054 0.009
Echinococcus granulosus histone deacetylase 6 0.0365 0.1108 0.1875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0086 0.0229 0.0384
Echinococcus multilocularis Ankyrin 0.0015 0.0003 0.0004
Onchocerca volvulus 0.0086 0.0229 0.0948
Brugia malayi Uncoordinated protein 44 0.0014 0.0003 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0035 0.0145
Brugia malayi putative neuropeptide receptor 0.0086 0.0229 0.0682
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0119 0.0118
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0138 0.0576
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0085 0.0353
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0002 0.0004
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0003 0.0004
Echinococcus multilocularis smad 0.0015 0.0005 0.0007
Trypanosoma brucei histone deacetylase 1 0.0305 0.092 0.5347
Echinococcus granulosus dna polymerase kappa 0.0049 0.0112 0.0188
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0076 0.0198 0.0332
Loa Loa (eye worm) carboxylesterase 0.0076 0.0198 0.0197
Echinococcus granulosus fmrfamide receptor 0.0086 0.0229 0.0386
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0111 0.0462
Plasmodium vivax acyl-CoA synthetase, putative 0.0122 0.0342 0.0362
Entamoeba histolytica hypothetical protein 0.0022 0.0026 0.0193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0111 0.0462
Brugia malayi transcriptional regulator, Sir2 family protein 0.0015 0.0004 0.0011
Trichomonas vaginalis antibiotic synthetase, putative 0.0048 0.0108 0.0451
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0088 0.0148
Echinococcus multilocularis allatostatin A receptor 0.0086 0.0229 0.0386
Echinococcus multilocularis neuroligin 0.0076 0.0198 0.0334
Leishmania major phosphopantetheinyl transferase-like protein 0.0014 0.0003 0.0016
Mycobacterium ulcerans NAD-dependent deacetylase 0.0015 0.0004 0.0002
Schistosoma mansoni tsg101-related 0.0031 0.0054 0.0088
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0031 0.0055 0.0057
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0071 0.0148
Brugia malayi 6-phosphofructokinase 0.0057 0.0138 0.0411
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Trypanosoma cruzi polo-like protein kinase, putative 0.005 0.0114 0.0665
Loa Loa (eye worm) CYP4Cod1 0.002 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0182
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0026 0.0042
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0272 0.0459
Echinococcus granulosus Smad4 0.0015 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0058 0.0139 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.006 0.0251
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0559 0.1721 1
Entamoeba histolytica phosphofructokinase, putative 0.0057 0.0138 0.1059
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0043 0.025
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Brugia malayi MH1 domain containing protein 0.0015 0.0005 0.0013
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0014 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0114 0.0191
Echinococcus granulosus neuropeptide receptor A26 0.0086 0.0229 0.0386
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0092 0.0155
Toxoplasma gondii phosphofructokinase PFKII 0.0015 0.0006 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Schistosoma mansoni tar DNA-binding protein 0.0152 0.0436 0.0735
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus multilocularis sex peptide receptor 0.0086 0.0229 0.0386
Onchocerca volvulus 0.0086 0.0229 0.0948
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.015 0.025
Trypanosoma cruzi UDP-galactopyranose mutase 0.0047 0.0107 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0053 0.022
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0071 0.0148
Loa Loa (eye worm) hypothetical protein 0.0063 0.0155 0.0154
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.005 0.0206
Schistosoma mansoni histone deacetylase 0.0305 0.092 0.1554
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0022 0.0025 0.0148
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0029 0.005 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0113 0.0315 0.1314
Schistosoma mansoni patched 1 0.0043 0.0092 0.0153
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0006 0.0024
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0021 0.002
Echinococcus granulosus death domain containing protein 0.0014 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.0199
Schistosoma mansoni lamin 0.0027 0.0043 0.0069
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0037 0.0073 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0071 0.0414
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0112 0.0648
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0006 0.0024
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0071 0.0148
Schistosoma mansoni histone deacetylase hda2 0.0151 0.0433 0.0729
Echinococcus multilocularis serotonin receptor 0.0086 0.0229 0.0386
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0016 0.0026
Schistosoma mansoni smad 0.0015 0.0005 0.0005
Leishmania major ATP-dependent phosphofructokinase 0.0057 0.0138 0.0803
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0003 0.0002
Onchocerca volvulus 0.0027 0.0043 0.0171
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0118 0.035
Echinococcus multilocularis histone deacetylase 8 0.0151 0.0433 0.0731
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0063 0.0186
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0086 0.0229 0.0384
Trypanosoma cruzi ISWI complex protein 0.0016 0.0008 0.0045
Schistosoma mansoni chromobox protein 0.0086 0.0229 0.0385
Echinococcus granulosus g protein coupled receptor 0.0086 0.0229 0.0386
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0003 0.0007
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0063 0.0063
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0063 0.0062
Echinococcus granulosus WGR domain containing protein 0.0132 0.0374 0.0632
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0274 0.046
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0071 0.0118
Echinococcus multilocularis fmrfamide receptor 0.0086 0.0229 0.0386
Trypanosoma brucei polo-like protein kinase 0.005 0.0114 0.0665
Brugia malayi Protein kinase domain containing protein 0.0024 0.0032 0.0094
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0162 0.0482
Loa Loa (eye worm) fli-1 protein 0.0223 0.0659 0.0659
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0031 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0112 0.031 0.2384
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0255 0.0761 0.1286
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0029 0.005 0.0533
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0098 0.0265 0.0448
Entamoeba histolytica hypothetical protein 0.0032 0.0057 0.0433
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0052 0.0056
Echinococcus granulosus Chromo domain 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0163 0.0472 0.0471
Plasmodium falciparum zinc finger protein, putative 0.0018 0.0014 0.0014
Brugia malayi GnHR receptor homolog 0.0086 0.0229 0.0682
Echinococcus granulosus expressed protein 0.0422 0.1289 0.2181
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0111 0.0462
Loa Loa (eye worm) Smad1 0.0015 0.0005 0.0004
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0026 0.004
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0076 0.0198 0.0332
Leishmania major DNA repair protein, putative 0.0056 0.0132 0.077
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0104
Leishmania major pyruvate kinase 0.0033 0.0063 0.0365
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0002 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0122 0.0342 0.0734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0011 0.0045
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0063 0.0365
Loa Loa (eye worm) hypothetical protein 0.0305 0.092 0.092
Echinococcus multilocularis neuropeptide Y receptor 0.0086 0.0229 0.0386
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Mycobacterium leprae Probable lipase LipE 0.0036 0.0071 0.0148
Plasmodium vivax ataxin-2 like protein, putative 0.007 0.0178 0.0189
Loa Loa (eye worm) glutaminase 0.0277 0.083 0.083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0118 0.049
Leishmania major hypothetical protein, conserved 0.0024 0.0032 0.0185
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0016 0.0169
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0472 0.0498
Brugia malayi N-terminal motif family protein 0.0181 0.0529 0.1579
Onchocerca volvulus 0.0086 0.0229 0.0948
Brugia malayi G protein-coupled receptor 0.0086 0.0229 0.0682
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0055 0.0317
Entamoeba histolytica hypothetical protein 0.0014 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0106
Onchocerca volvulus 0.0086 0.0229 0.0948
Brugia malayi CXXC zinc finger family protein 0.0153 0.0439 0.1309
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0173 0.0503 0.0532
Echinococcus multilocularis chromobox protein 1 0.0086 0.0229 0.0387
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Brugia malayi transcriptional regulator, Sir2 family protein 0.0015 0.0004 0.0011
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0026 0.0025
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0015 0.0004 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0221 0.0655 0.0654
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0026 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.011 0.0457
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0022 0.0025 0.0148
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0031 0.0055 0.0161
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.015 0.0159
Echinococcus multilocularis carboxylesterase 5A 0.0451 0.1381 0.2336
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0048 0.0108 0.0229
Trichomonas vaginalis hypothetical protein 0.0014 0.0002 0.0006
Echinococcus granulosus g-protein coupled receptor 0.0086 0.0229 0.0386
Leishmania major 4-coumarate:coa ligase-like protein 0.0163 0.0472 0.274
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0173 0.0503 0.0532
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.005 0.0288
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0076
Schistosoma mansoni histone deacetylase 4 5 0.0358 0.1086 0.1836
Onchocerca volvulus Glucosylceramidase homolog 0.0275 0.0826 0.3443
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0026 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Entamoeba histolytica hypothetical protein 0.0014 0.0002 0.0009
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0043 0.025
Onchocerca volvulus Neuropeptide F receptor homolog 0.0086 0.0229 0.0948
Chlamydia trachomatis pyruvate kinase 0.0033 0.0063 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Schistosoma mansoni DNA ligase IV 0.0027 0.0043 0.007
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0043 0.0095 0.0723
Brugia malayi beta-lactamase 0.0036 0.0071 0.0211
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0071 0.0071
Schistosoma mansoni topbp1 0.0027 0.0043 0.007
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0076 0.0198 0.0334
Echinococcus granulosus regulator of G protein signaling 7 0.0031 0.0054 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0098 0.0407
Plasmodium vivax replication factor C subunit 1, putative 0.0027 0.0043 0.0045
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0026 0.004
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0138 0.0576
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus poly ADP ribose polymerase 1 0.0425 0.1299 0.2197
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0053 0.022
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0086 0.0229 0.0384
Schistosoma mansoni DNA polymerase IV / kappa 0.0015 0.0005 0.0006
Trypanosoma brucei histone deacetylase 3 0.0358 0.1086 0.6313
Echinococcus granulosus acetylcholinesterase 0.0451 0.1381 0.2336
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Loa Loa (eye worm) hypothetical protein 0.0056 0.0132 0.0132
Echinococcus granulosus poly (ADP ribose) polymerase 0.0066 0.0166 0.0279
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.011 0.0305 0.0655
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0015 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0152 0.0436 0.0735
Loa Loa (eye worm) phosphofructokinase 0.0057 0.0138 0.0138
Schistosoma mansoni myosin xvIII 0.0086 0.0229 0.0384
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0086 0.0229 0.0386
Echinococcus granulosus muscleblind protein 0.1074 0.3345 0.566
Loa Loa (eye worm) histone deacetylase 3 0.0305 0.092 0.092
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0021 0.0061
Brugia malayi hypothetical protein 0.007 0.0178 0.0531
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0048 0.0108 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0112 0.0648
Echinococcus granulosus dnaJ subfamily B 0.1886 0.5909 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0086 0.0229 0.0386
Loa Loa (eye worm) RNA binding protein 0.0152 0.0436 0.0435
Schistosoma mansoni SET domain protein 0.0016 0.0006 0.0008
Entamoeba histolytica hypothetical protein 0.0014 0.0002 0.0009
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0048 0.0108 0.0629
Schistosoma mansoni 3-dehydroquinate synthase 0.011 0.0305 0.0514
Giardia lamblia DINP protein human, muc B family 0.0049 0.0112 0.1207
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.015 0.0156
Brugia malayi DKFZp564C0469 protein 0.0027 0.0043 0.0127
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0086 0.0229 0.0682
Schistosoma mansoni regulator of G protein signaling 0.0031 0.0054 0.0088
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0086 0.0229 0.0228
Echinococcus multilocularis G protein coupled receptor 139 0.0086 0.0229 0.0386
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0006
Echinococcus multilocularis g-protein coupled receptor 0.0086 0.0229 0.0386
Leishmania major histone deacetylase, putative 0.0358 0.1086 0.6313
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0014 0.0001 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.007 0.0178 0.0189
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0112 0.031 0.2384
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0071 0.0073
Schistosoma mansoni chromatin regulatory protein sir2 0.0015 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0026 0.004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0408 0.0689
Loa Loa (eye worm) hypothetical protein 0.0098 0.0268 0.0267
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0048 0.0108 0.0115
Echinococcus granulosus nibrin 0.0027 0.0043 0.0072
Schistosoma mansoni tankyrase 0.0032 0.0057 0.0094
Chlamydia trachomatis chorismate synthase 0.2998 0.9417 1
Echinococcus granulosus orexin receptor type 2 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.0033 0.0063 0.0062
Echinococcus granulosus histone deacetylase 0.0358 0.1086 0.1838
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Echinococcus multilocularis pyruvate kinase 0.0033 0.0063 0.0105
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0015 0.0004 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0086 0.0229 0.0386
Leishmania major DNA damage repair protein, putative 0.0015 0.0005 0.003
Loa Loa (eye worm) hypothetical protein 0.0106 0.0292 0.0292
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0015 0.0005 0.0005
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0048 0.0108 0.0229
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0033 0.0138
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0274 0.046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0162 0.0169
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0048 0.0108 0.0629
Plasmodium falciparum cysteine repeat modular protein 1 0.0024 0.0032 0.0033
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0015 0.0006 0.0043
Brugia malayi Carboxylesterase family protein 0.0451 0.1381 0.4127
Loa Loa (eye worm) 6-phosphofructokinase 0.0057 0.0138 0.0138
Echinococcus multilocularis dnaJ subfamily B 0.1886 0.5909 1
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0048 0.0108 0.0112
Echinococcus granulosus tm gpcr rhodopsin 0.0086 0.0229 0.0386
Brugia malayi Smad1 0.0015 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Entamoeba histolytica serine/threonine protein kinase, putative 0.005 0.0114 0.0877
Echinococcus multilocularis G-protein coupled receptor, putative 0.0086 0.0229 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0092 0.0155
Onchocerca volvulus 0.0773 0.2395 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0086 0.0229 0.0386
Echinococcus multilocularis neuropeptide FF receptor 2 0.0086 0.0229 0.0386
Trypanosoma cruzi PAB1-binding protein , putative 0.007 0.0178 0.1035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Echinococcus granulosus g protein coupled receptor 0.0086 0.0229 0.0386
Leishmania major histone deacetylase, putative 0.0305 0.092 0.5347
Brugia malayi WGR domain containing protein 0.0425 0.1299 0.3882
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1281 0.5349
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.005 0.0206
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0025
Schistosoma mansoni BC026374 protein (S09 family) 0.0076 0.0198 0.0332
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0118 0.0196
Echinococcus granulosus expressed conserved protein 0.0094 0.0253 0.0426
Toxoplasma gondii histone deacetylase HDAC1 0.0358 0.1086 0.1154
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.015 0.0252
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Onchocerca volvulus Histone deacetylase 10 homolog 0.0151 0.0433 0.18
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0162 0.0273
Brugia malayi Pre-SET motif family protein 0.0679 0.21 0.6278
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0028 0.0047 0.0078
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0016 0.0026
Loa Loa (eye worm) carboxylesterase 0.0451 0.1381 0.138
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0016 0.0026
Echinococcus granulosus histone deacetylase 6 0.0358 0.1086 0.1838
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus chromobox protein 1 0.0086 0.0229 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.015 0.0156
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0022 0.0025 0.0148
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0274 0.0462
Brugia malayi Tnks protein 0.0032 0.0057 0.0169
Brugia malayi PXA domain containing protein 0.0022 0.0026 0.0075
Echinococcus granulosus dna polymerase eta 0.0049 0.0112 0.0188
Echinococcus multilocularis ubiquitin specific protease 41 0.0029 0.005 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0005 0.003
Trypanosoma cruzi UDP-galactopyranose mutase 0.0047 0.0107 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Leishmania major 4-coumarate:coa ligase-like protein 0.0163 0.0472 0.274
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0003 0.0004
Entamoeba histolytica acyl-CoA synthetase, putative 0.0163 0.0472 0.3628
Plasmodium vivax acetyl-CoA synthetase, putative 0.0048 0.0108 0.0114
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0015 0.0006 0.0007
Echinococcus multilocularis chromobox protein 1 0.0086 0.0229 0.0387
Schistosoma mansoni opsin-like receptor 0.0086 0.0229 0.0384
Leishmania major 4-coumarate:coa ligase-like protein 0.0163 0.0472 0.274
Toxoplasma gondii histone deacetylase HDAC4 0.0151 0.0433 0.046
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0047 0.0107 0.0177
Schistosoma mansoni pyruvate kinase 0.0017 0.0011 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0472 0.1408
Brugia malayi Cytochrome P450 family protein 0.002 0.002 0.0058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Schistosoma mansoni smad1 5 8 and 0.0015 0.0005 0.0005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0292 0.0873
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0086 0.0229 0.0386
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0043 0.025
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0163 0.0472 0.1015
Entamoeba histolytica hypothetical protein 0.0046 0.0103 0.0792
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0015 0.0006 0.0004
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0076 0.0198 0.0334
Trypanosoma brucei ISWI complex protein 0.0016 0.0008 0.0045
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0106
Chlamydia trachomatis dehyroquinate synthase 0.011 0.0305 0.0321
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0015 0.0004 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0005 0.003
Onchocerca volvulus 0.0086 0.0229 0.0948
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.042 0.1281 0.3829
Echinococcus granulosus tm gpcr rhodopsin 0.0086 0.0229 0.0386
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0026 0.0042
Onchocerca volvulus 0.0036 0.0071 0.029
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0016 0.0026
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.007 0.0178 0.1035
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0425 0.1299 1
Trypanosoma cruzi histone deacetylase, putative 0.0358 0.1086 0.6313
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0075 0.0195 0.0204
Trypanosoma cruzi DNA damage repair protein, putative 0.0015 0.0005 0.003
Toxoplasma gondii histone deacetylase SIR2 0.0015 0.0004 0.0005
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1819 0.5695 0.9638
Chlamydia trachomatis endonuclease IV 0.0077 0.02 0.021
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0079 0.0205 0.1193
Onchocerca volvulus 0.0086 0.0229 0.0948
Brugia malayi Carboxylesterase family protein 0.0451 0.1381 0.4127
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.042 0.1281 0.1281
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.015 0.0869
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0028 0.0047 0.0138
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0106
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0027 0.0043 0.0856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0086 0.0229 0.0386
Echinococcus multilocularis lamin 0.0027 0.0043 0.0071
Brugia malayi Pax transcription activation domain interacting protein 0.0027 0.0043 0.0127
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.02 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0026 0.0041
Schistosoma mansoni rotamase 0.0045 0.0098 0.0163
Echinococcus granulosus Chromobox protein 3 0.0014 0.0002 0.0002
Toxoplasma gondii histone deacetylase HDAC3 0.0305 0.092 0.0977
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.01 0.0415
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.007 0.0115
Echinococcus granulosus neuropeptide Y receptor 0.0086 0.0229 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Onchocerca volvulus 0.0086 0.0229 0.0948
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0086 0.0229 0.0386
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0113 0.0315 0.0532
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0002 0.0006
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1479 0.4622 1
Brugia malayi RE15519p 0.0086 0.0229 0.0682
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0048 0.0108 0.0182
Giardia lamblia GTOR 0.0051 0.0118 0.1273
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0163 0.0472 0.0498
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0043 0.0095 0.0549
Loa Loa (eye worm) hypothetical protein 0.0122 0.0342 0.0341
Chlamydia trachomatis protoporphyrinogen oxidase 0.0047 0.0107 0.011
Echinococcus multilocularis pyruvate kinase 0.0026 0.0041 0.0068
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0014 0.0003 0.0002
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0057 0.0136 0.0144
Echinococcus granulosus neuropeptides capa receptor 0.0086 0.0229 0.0386
Echinococcus granulosus serotonin receptor 0.0086 0.0229 0.0386
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0057 0.0138 0.0803
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0137 0.0799
Echinococcus multilocularis muscleblind protein 0.1074 0.3345 0.566
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0075 0.0195 0.0416
Loa Loa (eye worm) hypothetical protein 0.0163 0.0472 0.0471
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0031 0.0056 0.0094
Giardia lamblia Kinase, PLK 0.005 0.0114 0.1238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Entamoeba histolytica acyl-coA synthetase, putative 0.0163 0.0472 0.3628
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0049 0.0112 0.0188
Mycobacterium ulcerans hypothetical protein 0.0015 0.0005 0.0003
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0625 0.1928 0.4168
Echinococcus granulosus tissue type plasminogen activator 0.0024 0.0032 0.0053
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0026 0.0043
Echinococcus multilocularis regulator of G protein signaling 7 0.0031 0.0054 0.009
Mycobacterium ulcerans carboxylesterase, LipT 0.0076 0.0198 0.0207
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0026 0.0076
Echinococcus granulosus lysine specific histone demethylase 1A 0.0047 0.0107 0.0179
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0076 0.0198 0.0825
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0026 0.0042
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0118 0.0684
Schistosoma mansoni cpg binding protein 0.0153 0.0439 0.0739
Trypanosoma cruzi histone deacetylase, putative 0.0151 0.0433 0.2515
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0006 0.0024
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0163 0.0472 0.0498
Echinococcus granulosus neuropeptide FF receptor 2 0.0086 0.0229 0.0386
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1281 0.5349
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0065 0.0271
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0015 0.0004 0.0025
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0043 0.0095 0.0549
Echinococcus multilocularis Chromo domain 0.0014 0.0002 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0011 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Leishmania major DNA polymerase eta, putative 0.0049 0.0112 0.0648
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0189 0.0318
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.015 0.025
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0048 0.0108 0.0629
Trypanosoma cruzi histone deacetylase 1, putative 0.0305 0.092 0.5347
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0063 0.013
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.005 0.0114 0.0193
Onchocerca volvulus 0.0086 0.0229 0.0948
Echinococcus multilocularis neuropeptide Y receptor 0.0086 0.0229 0.0386
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0064 0.037
Echinococcus multilocularis histone deacetylase 6 0.0365 0.1108 0.1875
Toxoplasma gondii histone lysine methyltransferase SET1 0.0293 0.088 0.0935
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0064
Echinococcus granulosus carboxylesterase 5A 0.0451 0.1381 0.2336
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0028 0.0047 0.0078
Schistosoma mansoni amine GPCR 0.0086 0.0229 0.0384
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0071 0.0296
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0024 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Brugia malayi amine oxidase, flavin-containing family protein 0.0047 0.0107 0.0317
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0025
Echinococcus granulosus lysine specific histone demethylase 1A 0.0047 0.0107 0.0179
Brugia malayi Tachykinin-like peptides receptor 99D 0.0086 0.0229 0.0682
Brugia malayi neuropeptide F receptor 0.0086 0.0229 0.0682
Loa Loa (eye worm) hypothetical protein 0.0057 0.0137 0.0137
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0113 0.0315 0.1314
Trichomonas vaginalis hypothetical protein 0.0018 0.0014 0.0056
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0071 0.0296
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0031 0.0054 0.0053
Leishmania major pyruvate kinase 0.0033 0.0063 0.0365
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0234 0.0694 0.1174
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Loa Loa (eye worm) 6-phosphofructokinase 0.0057 0.0138 0.0138
Echinococcus multilocularis tissue type plasminogen activator 0.0024 0.0032 0.0053
Plasmodium falciparum DNA repair protein REV1, putative 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0051 0.0119 0.0488
Trichomonas vaginalis helicase, putative 0.0035 0.0066 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0026 0.0041
Brugia malayi WGR domain containing protein 0.0234 0.0694 0.2074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0011 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0094 0.0392
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0026 0.0042
Trichomonas vaginalis chromobox protein, putative 0.0086 0.0229 0.0956
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0049 0.0112 0.0236
Echinococcus multilocularis somatostatin receptor 0.0086 0.0229 0.0386
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0048 0.0108 0.0629
Schistosoma mansoni hypothetical protein 0.0086 0.0229 0.0384
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0021 0.0081
Brugia malayi Protein cec-1. 0.0014 0.0002 0.0004
Plasmodium falciparum histone deacetylase 1 0.0305 0.092 0.0976
Mycobacterium ulcerans DNA polymerase IV 0.0049 0.0112 0.0116
Echinococcus granulosus acetylcholinesterase 0.0451 0.1381 0.2336
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0071 0.0211
Brugia malayi hypoxia-induced factor 1 0.0151 0.0434 0.1296
Echinococcus multilocularis expressed protein 0.0045 0.0098 0.0165
Schistosoma mansoni Smad4 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0071 0.0148
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0026 0.0075
Schistosoma mansoni amine GPCR 0.0086 0.0229 0.0384
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0025
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0037 0.0073 0.0122
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0015 0.0004 0.0029
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0173 0.0503 1
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0006 0.0024
Echinococcus multilocularis 6 phosphofructokinase 0.0057 0.0138 0.0233
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0029 0.005 0.0288
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0015 0.0006 0.006
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0014 0.0001 0.0003
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1479 0.4622 1
Onchocerca volvulus 0.0052 0.0122 0.0502
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0408 0.0689
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0029 0.005 0.0081
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0015 0.0004 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.0305 0.092 0.3841
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Toxoplasma gondii histone lysine-specific demethylase 0.0047 0.0107 0.0113
Brugia malayi Histone deacetylase family protein 0.0358 0.1086 0.3246
Echinococcus granulosus lamin dm0 0.0027 0.0043 0.0071
Echinococcus granulosus replication factor c subunit 1 0.0027 0.0043 0.0072
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0048 0.0108 0.0629
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0025 0.0036 0.0272
Echinococcus granulosus smad 0.0015 0.0005 0.0007
Giardia lamblia Sirtuin type 2 0.0015 0.0004 0.004
Trypanosoma brucei cytochrome P450, putative 0.002 0.002 0.0116
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0113 0.0315 0.0532
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus neuropeptide s receptor 0.0086 0.0229 0.0386
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0112 0.0648
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0026 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0049 0.0112 0.0116
Brugia malayi M-phase phosphoprotein, mpp8 0.0014 0.0002 0.0004
Schistosoma mansoni topbp1 0.0027 0.0043 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0085 0.0353
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0041 0.0088 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0025
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0043 0.0179
Echinococcus granulosus pyruvate kinase 0.0033 0.0063 0.0105
Plasmodium falciparum histone deacetylase 2 0.0358 0.1086 0.1153
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0122 0.0342 0.0341
Echinococcus granulosus ubiquitin specific protease 41 0.0029 0.005 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0063 0.0062
Onchocerca volvulus 0.0076 0.0198 0.0819
Schistosoma mansoni gliotactin 0.0076 0.0198 0.0332
Leishmania major mitochondrial DNA polymerase beta 0.0559 0.1721 1
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0028 0.0047 0.0049
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0162 0.0271
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0038 0.0061
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0071 0.0148
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0048 0.0108 0.0229
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0032 0.0185
Onchocerca volvulus 0.0024 0.0032 0.0126
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.0029 0.0048
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0028 0.0047 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0071 0.0075
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0086 0.0229 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Brugia malayi MH2 domain containing protein 0.0015 0.0005 0.0013
Echinococcus granulosus BC026374 protein S09 family 0.0076 0.0198 0.0334
Onchocerca volvulus 0.0036 0.0071 0.029
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0002 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1281 0.5349
Brugia malayi RNA, U transporter 1 0.0162 0.047 0.1403
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0043 0.0179
Schistosoma mansoni neuropeptide receptor 0.0086 0.0229 0.0384
Schistosoma mansoni 6-phosphofructokinase 0.0057 0.0138 0.0231
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0022 0.0025 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.015 0.0252
Echinococcus multilocularis chromatin regulatory protein sir2 0.0015 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0092 0.0384
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0076 0.0198 0.0422
Mycobacterium tuberculosis Conserved hypothetical protein 0.0294 0.0886 0.1913
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0408 0.0687
Echinococcus multilocularis tar DNA binding protein 0.0152 0.0436 0.0736
Loa Loa (eye worm) hypothetical protein 0.0052 0.0123 0.0122
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.005 0.0114 0.0114
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0015 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor 0.0086 0.0229 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0065 0.0269
Onchocerca volvulus 0.0048 0.0108 0.0445
Onchocerca volvulus 0.0076 0.0198 0.0819
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0048 0.0108 0.0829
Schistosoma mansoni histone deacetylase 1 2 3 0.0151 0.0433 0.0729
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0112 0.0332
Loa Loa (eye worm) transcriptional regulator 0.0015 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0031 0.0056 0.0092
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0048 0.0108 0.0229
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0108 0.0322
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Schistosoma mansoni intermediate filament proteins 0.0027 0.0043 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0408 0.0687
Schistosoma mansoni hypothetical protein 0.0041 0.0087 0.0145
Leishmania major GTP-binding protein, putative 0.0031 0.0055 0.0317
Mycobacterium ulcerans hypothetical protein 0.0036 0.0071 0.0073
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0283 0.0851 0.0904
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Trichomonas vaginalis rotamase, putative 0.0045 0.0098 0.0407
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0272 0.081
Onchocerca volvulus 0.0086 0.0229 0.0948
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Entamoeba histolytica hypothetical protein 0.0066 0.0166 0.1271
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0043 0.0179
Echinococcus multilocularis Smad4 0.0015 0.0005 0.0007
Schistosoma mansoni DNA polymerase eta 0.0049 0.0112 0.0186
Brugia malayi TAR-binding protein 0.0152 0.0436 0.1301
Brugia malayi NAD-dependent deacetylase SIRT1 0.0113 0.0315 0.094
Onchocerca volvulus DNA ligase 3 homolog 0.0056 0.0132 0.0546
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Plasmodium vivax 6-phosphofructokinase, putative 0.0015 0.0006 0.0006
Loa Loa (eye worm) carboxylesterase 0.0076 0.0198 0.0197
Brugia malayi hypothetical protein 0.0022 0.0026 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0321 0.0688
Mycobacterium ulcerans 6-phosphofructokinase 0.0057 0.0138 0.0144
Schistosoma mansoni histone deacetylase 4 5 0.0358 0.1086 0.1836
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0063 0.0062
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0016 0.0046
Schistosoma mansoni ets-related 0.0223 0.0659 0.1113
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0137 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0026 0.0041
Trichomonas vaginalis histone deacetylase, putative 0.0305 0.092 0.3841
Echinococcus granulosus GTP binding nuclear protein Ran 0.0031 0.0055 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0111 0.0462
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0026 0.004
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0022 0.0025 0.0148
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0408 0.0689
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0047 0.0107 0.0113
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0292 0.0873
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0043 0.0179
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0015 0.0004 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Schistosoma mansoni cpg binding protein 0.0161 0.0466 0.0786
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Giardia lamblia Hypothetical protein 0.0015 0.0004 0.004
Entamoeba histolytica hypothetical protein 0.0022 0.0026 0.0193
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0048 0.0108 0.0114
Echinococcus multilocularis GPCR, family 2 0.0034 0.0063 0.0106
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.011 0.0305 0.0655
Plasmodium falciparum histone deacetylase, putative 0.0358 0.1086 0.1153
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0086 0.0229 0.0386
Schistosoma mansoni ran 0.0031 0.0055 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1281 0.5349
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0006 0.0024
Brugia malayi Death domain containing protein 0.0014 0.0003 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0118 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0026 0.0106
Plasmodium falciparum chorismate synthase 0.2998 0.9417 1
Schistosoma mansoni neuropeptide receptor 0.0086 0.0229 0.0384
Brugia malayi SET domain containing protein 0.0021 0.0024 0.0069
Brugia malayi PXA domain containing protein 0.0022 0.0026 0.0075
Leishmania major sir2-family protein-like protein 0.0015 0.0004 0.0025
Echinococcus granulosus expressed protein 0.0045 0.0098 0.0165
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0163 0.0472 0.0498
Echinococcus granulosus tar DNA binding protein 0.0152 0.0436 0.0736
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.005 0.0288
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0163 0.0472 0.0471
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0026 0.0042
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0011 0.0012
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0031 0.0055 0.0054
Schistosoma mansoni adenoreceptor 0.0086 0.0229 0.0384
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0106
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0015 0.0004 0.0004
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0063 0.0255
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0425 0.1299 0.2197
Echinococcus granulosus snurportin 1 0.061 0.1881 0.3183
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.0018
Toxoplasma gondii kringle domain-containing protein 0.0024 0.0032 0.0034
Toxoplasma gondii ATPase, AAA family protein 0.0027 0.0043 0.0046
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0047 0.0107 0.0113
Onchocerca volvulus 0.0153 0.0439 0.1825
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Toxoplasma gondii hypothetical protein 0.009 0.0242 0.0257
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0063 0.0188
Giardia lamblia Replication factor C, subunit 1 0.0027 0.0043 0.0462
Schistosoma mansoni amine GPCR 0.0086 0.0229 0.0384
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0086 0.0229 0.0386
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0005 0.0004
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0047 0.0107 0.0113
Brugia malayi Kringle domain containing protein 0.0024 0.0032 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Echinococcus granulosus mixed lineage leukemia protein mll 0.0041 0.0088 0.0148
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0118 0.0198
Leishmania major hypothetical protein, conserved 0.007 0.0178 0.1035
Entamoeba histolytica hypothetical protein 0.0032 0.0057 0.0433
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0063 0.0365
Trypanosoma brucei DNA repair protein, putative 0.0056 0.0132 0.077
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0162 0.0273
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0015 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0086 0.0229 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0026 0.0106
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0031 0.0055 0.0587
Schistosoma mansoni neuropeptide receptor 0.0086 0.0229 0.0384
Schistosoma mansoni amine oxidase 0.0047 0.0107 0.0177
Mycobacterium ulcerans monoamine oxidase 0.0047 0.0107 0.011
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0021 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.0563 0.2351
Treponema pallidum fructose-bisphosphate aldolase 0.0154 0.0444 0.8808
Plasmodium falciparum acyl-CoA synthetase 0.0122 0.0342 0.0362
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0063 0.0067
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0071 0.012
Echinococcus granulosus tumor protein p63 0.0339 0.1027 0.1737
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0163 0.0472 0.1015
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) sirtuin 4 0.0015 0.0004 0.0004
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0672 0.2078 0.2204
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0029 0.005 0.0083
Schistosoma mansoni hypothetical protein 0.0073 0.0186 0.0312
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0043 0.025
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0118 0.0901
Echinococcus granulosus histone deacetylase 3 0.0305 0.092 0.1556
Trypanosoma brucei unspecified product 0.0034 0.0064 0.037
Schistosoma mansoni hypothetical protein 0.0086 0.0229 0.0384
Echinococcus granulosus dro:myosuppressin receptor 0.0086 0.0229 0.0386
Brugia malayi SET domain containing protein 0.0016 0.0006 0.0018
Leishmania major histone deacetylase, putative 0.0358 0.1086 0.6313
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0043 0.0179
Mycobacterium ulcerans acetyl-CoA synthetase 0.0048 0.0108 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1281 0.5349
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0274 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0045 0.0098 0.0097
Brugia malayi hypothetical protein 0.0037 0.0073 0.0216
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0047 0.0107 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0071 0.0414
Entamoeba histolytica hypothetical protein 0.0032 0.0057 0.0433
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0063 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0873 0.3643
Schistosoma mansoni chromatin regulatory protein sir2 0.0015 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0011 0.0018
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0086 0.0229 0.0228
Echinococcus granulosus TGF beta signal transducer SmadC 0.0015 0.0005 0.0007
Mycobacterium tuberculosis Conserved protein 0.0036 0.0071 0.0148
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0002 0.0004
Brugia malayi 6-phosphofructokinase 0.0057 0.0138 0.0411
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0148 0.0148
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0018
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0045 0.0098 0.0291
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0049 0.0111 0.0462
Brugia malayi G-protein coupled receptor 0.0086 0.0229 0.0682
Loa Loa (eye worm) transcription factor SMAD2 0.0221 0.0655 0.0654
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0086 0.0229 0.0682
Schistosoma mansoni histone deacetylase hda2 0.0365 0.1108 0.1873
Mycobacterium tuberculosis Conserved protein 0.0036 0.0071 0.0148
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0234 0.0694 0.1172
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0015 0.0006 0.0004
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0022 0.0026 0.0198
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0014 0.0003 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0408 0.0407
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0048 0.0108 0.0322
Loa Loa (eye worm) hypothetical protein 0.1074 0.3345 0.3345
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0026 0.0106
Echinococcus granulosus alpha 1A adrenergic receptor 0.0086 0.0229 0.0386
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0028 0.0047 0.0046
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0283 0.0851 0.1837
Echinococcus granulosus histone deacetylase 6 0.0358 0.1086 0.1838
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Schistosoma mansoni smad1 5 8 and 0.0015 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Echinococcus multilocularis g protein coupled receptor 0.0086 0.0229 0.0386
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0137 0.0232
Trichomonas vaginalis histone deacetylase, putative 0.0305 0.092 0.3841
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0047 0.0107 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0008 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0274 0.0462
Echinococcus multilocularis para nitrobenzyl esterase 0.0076 0.0198 0.0334
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0049 0.0112 0.0186
Echinococcus multilocularis orexin receptor type 2 0.0086 0.0229 0.0386
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0011 0.0064
Loa Loa (eye worm) transcriptional regulator 0.0015 0.0004 0.0004
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Leishmania major protein kinase, putative 0.0017 0.001 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0049 0.0112 0.0465
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0011 0.0031
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0181 0.0529 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0085 0.0353
Onchocerca volvulus 0.0086 0.0229 0.0948
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0011 0.0045
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0049 0.0112 0.0648
Echinococcus multilocularis replication factor c subunit 1 0.0027 0.0043 0.0072
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.0686 0.1478
Loa Loa (eye worm) oxidoreductase 0.0048 0.0108 0.0108
Chlamydia trachomatis DNA ligase 0.0027 0.0043 0.0043
Brugia malayi histone deacetylase 3 (HD3) 0.0305 0.092 0.2749
Echinococcus granulosus 7TM GPCR rhodopsin 0.0086 0.0229 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Toxoplasma gondii histone deacetylase HDAC2 0.0305 0.092 0.0977
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0104
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0305 0.092 0.3841
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.002 0.0019
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0005 0.003
Trypanosoma cruzi polo-like protein kinase, putative 0.005 0.0114 0.0665
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0035 0.0145
Giardia lamblia DNA damage repair protein 0.0015 0.0005 0.005
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0048 0.0108 0.0108
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0321 0.0688
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0086 0.0229 0.0384
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0047 0.0107 0.0177
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.02 0.0427
Schistosoma mansoni tsg101-related 0.0031 0.0054 0.0088
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0472 0.0498
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0064
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0048 0.0108 0.0229
Loa Loa (eye worm) beta-lactamase 0.0036 0.0071 0.0071
Brugia malayi chromobox protein homolog 3 0.0048 0.011 0.0326
Trichomonas vaginalis set domain proteins, putative 0.0773 0.2395 1
Mycobacterium ulcerans endonuclease IV 0.0077 0.02 0.021
Loa Loa (eye worm) hypothetical protein 0.01 0.0274 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0053 0.022
Schistosoma mansoni amine GPCR 0.0086 0.0229 0.0384
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0118 0.0901
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0071 0.0414
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0033 0.0192
Schistosoma mansoni biogenic amine (5HT) receptor 0.0086 0.0229 0.0384
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0048 0.0108 0.0229
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0071 0.0073
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0086 0.0229 0.0386
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0041 0.0087 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Echinococcus multilocularis serotonin receptor 0.0086 0.0229 0.0386
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0063 0.0365
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0048 0.0108 0.0115
Toxoplasma gondii peptidylprolyl isomerase 0.0043 0.0095 0.01
Echinococcus multilocularis expressed conserved protein 0.0094 0.0253 0.0426
Brugia malayi histone deacetylase 11 0.0151 0.0433 0.1292
Echinococcus granulosus tm gpcr rhodopsin 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Brugia malayi Dopamine receptor protein 2 0.0086 0.0229 0.0682
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0079 0.0205 0.1193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0181
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0029 0.005 0.0083
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0033 0.0194
Echinococcus multilocularis cpg binding protein 0.0161 0.0466 0.0788
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0197 0.058 0.1733
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0029 0.005 0.0147
Schistosoma mansoni amine GPCR 0.0086 0.0229 0.0384
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0452 0.1385 0.147
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0121 0.0505
Brugia malayi hypothetical protein 0.0027 0.0043 0.0127
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0108 0.0229
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.01 0.0297
Loa Loa (eye worm) hypothetical protein 0.0164 0.0474 0.0473
Echinococcus granulosus poly adp ribose polymerase 2 0.0234 0.0694 0.1174
Schistosoma mansoni chromatin regulatory protein sir2 0.0113 0.0315 0.053
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.005 0.0114 0.0665
Brugia malayi CHD4 protein 0.0023 0.0029 0.0086
Mycobacterium tuberculosis Conserved protein 0.0036 0.0071 0.0148
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0202 0.0595 0.1004
Onchocerca volvulus 0.0027 0.0043 0.0171
Entamoeba histolytica hypothetical protein 0.0032 0.0057 0.0433
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0026 0.0106
Plasmodium falciparum protoporphyrinogen oxidase 0.0047 0.0107 0.0113
Brugia malayi serine/threonine-protein kinase plk-2 0.005 0.0114 0.034
Brugia malayi PAS domain containing protein 0.0049 0.0111 0.0331
Toxoplasma gondii propionate-CoA ligase 0.0048 0.0108 0.0115
Mycobacterium ulcerans dehydrogenase 0.0047 0.0107 0.011
Leishmania major hypothetical protein, conserved 0.0056 0.0132 0.077
Onchocerca volvulus 0.0038 0.0077 0.0313
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0472 0.0498
Brugia malayi MH2 domain containing protein 0.0221 0.0655 0.1956
Echinococcus granulosus somatostatin receptor 0.0086 0.0229 0.0386
Echinococcus granulosus 7tm_1 domain containing protein 0.0086 0.0229 0.0386
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0011 0.0064
Onchocerca volvulus Serine\/threonine kinase homolog 0.005 0.0114 0.0471
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0031
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0043 0.0095 0.0549
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0051 0.0119 0.0353
Onchocerca volvulus 0.0076 0.0198 0.0819
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0108 0.0322
Brugia malayi regulator of G-protein signaling egl-10 0.0031 0.0054 0.0159
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.0117 0.0198
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0002 0.0002
Mycobacterium ulcerans epimerase 0.002 0.0021 0.002
Schistosoma mansoni cpg binding protein 0.0161 0.0466 0.0786
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0043 0.0126
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0027 0.0043 0.0327
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus chromobox protein 2 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0122 0.0342 0.0341
Plasmodium falciparum heterochromatin protein 1 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0015
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0015 0.0004 0.0025
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.01 0.0415
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0048 0.0108 0.0112
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.02 0.0212
Giardia lamblia Pyruvate kinase 0.0033 0.0063 0.0677
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0015 0.0004 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0086 0.0229 0.0386
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0048 0.0108 0.0112
Echinococcus granulosus Ankyrin 0.0015 0.0003 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0408 0.0689
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0002 0.0002
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0252 0.0425
Leishmania major DNA polymerase eta, putative 0.0015 0.0005 0.003
Echinococcus multilocularis protoporphyrinogen oxidase 0.0047 0.0107 0.0179
Echinococcus multilocularis histone deacetylase 3 0.0305 0.092 0.1556
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Brugia malayi hypothetical protein 0.0045 0.01 0.0297
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0054 0.0056
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0063 0.013
Trypanosoma brucei DNA damage repair protein, putative 0.0015 0.0005 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Schistosoma mansoni biogenic amine receptor 0.0086 0.0229 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0085 0.0353
Schistosoma mansoni chromatin regulatory protein sir2 0.0015 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0014 0.0003 0.0016
Schistosoma mansoni amine oxidase 0.0047 0.0107 0.0177
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.3183 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0003 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0182
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.0197 0.058 0.058
Loa Loa (eye worm) hypothetical protein 0.0451 0.1381 0.138
Trichomonas vaginalis ran, putative 0.0031 0.0055 0.0227
Loa Loa (eye worm) transcriptional regulator 0.0015 0.0004 0.0004
Mycobacterium ulcerans hypothetical protein 0.0163 0.0472 0.0498
Schistosoma mansoni neuropeptide f receptor 76f 0.0086 0.0229 0.0384
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0111 0.0462
Onchocerca volvulus 0.0036 0.0071 0.029
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0086 0.0229 0.0948
Brugia malayi RNA recognition motif domain containing protein 0.0152 0.0436 0.1301
Schistosoma mansoni chromosome transmission fidelity factor 0.0027 0.0043 0.007
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0022 0.0025 0.0042
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0048 0.0108 0.0629
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0092 0.0155
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0305 0.092 0.3841
Onchocerca volvulus 0.0086 0.0229 0.0948
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0065 0.0271
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0085 0.0494
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.006 0.0251
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0086 0.0229 0.0682
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0086 0.0229 0.0386
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0075 0.0195 0.0416
Echinococcus granulosus poly (ADP ribose) polymerase 0.0066 0.0166 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Echinococcus granulosus histone deacetylase 1 0.0305 0.092 0.1556
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0003 0.0016
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Schistosoma mansoni tar DNA-binding protein 0.0152 0.0436 0.0735
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0086 0.0229 0.0384
Echinococcus granulosus serine:threonine protein kinase PLK1 0.005 0.0114 0.0193
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0085 0.0494
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0679 0.21 0.21
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0033 0.0194
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0002 0.0004
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0305 0.092 0.3841
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0086 0.0229 0.0682
Brugia malayi Melatonin receptor type 1A 0.0086 0.0229 0.0682
Mycobacterium ulcerans 3-dehydroquinate synthase 0.011 0.0305 0.0321
Plasmodium falciparum pyruvate kinase 0.0033 0.0063 0.0066
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0015 0.0004 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0107 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0064 0.037
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Giardia lamblia Non ATPase subunit MPR1 of 26S proteasome 0.0022 0.0025 0.027
Leishmania major hypothetical protein, conserved 0.0036 0.0071 0.0414
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0064
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0108 0.0229
Echinococcus granulosus bloom syndrome protein 0.0045 0.01 0.0168
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0529 0.2202
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0108 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.005 0.0206
Loa Loa (eye worm) G-protein coupled receptor 0.0086 0.0229 0.0228
Plasmodium falciparum importin beta, putative 0.0057 0.0137 0.0145
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0026 0.004
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0048 0.0108 0.0229
Echinococcus multilocularis 0.0047 0.0107 0.0179
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0009
Schistosoma mansoni single-minded 0.0049 0.0111 0.0185
Trypanosoma cruzi histone deacetylase, putative 0.0358 0.1086 0.6313
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0014 0.0003 0.0002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0031 0.0055 0.0317
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0005 0.003
Schistosoma mansoni hypothetical protein 0.0086 0.0229 0.0384
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Brugia malayi phosphofructokinase 0.0057 0.0138 0.0411
Schistosoma mansoni importin beta-1 0.0057 0.0137 0.023
Loa Loa (eye worm) hypothetical protein 0.0324 0.0978 0.0978
Treponema pallidum DNA ligase (lig) 0.0027 0.0043 0.0807
Schistosoma mansoni myst-related protein 0.0018 0.0014 0.0021
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus multilocularis musashi 0.0027 0.0043 0.0071
Echinococcus multilocularis snurportin 1 0.061 0.1881 0.3183
Schistosoma mansoni DNA helicase recq5 0.0019 0.0016 0.0024
Echinococcus multilocularis expressed protein 0.0422 0.1289 0.2181
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0103 0.0431
Plasmodium falciparum replication factor C subunit 1, putative 0.0027 0.0043 0.0045
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0048 0.0108 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0049 0.0112 0.0111
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0014 0.0003 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0086 0.0229 0.0386
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Schistosoma mansoni tar DNA-binding protein 0.0152 0.0436 0.0735
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0321 0.0688
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0079 0.0205 0.1193
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0015 0.0004 0.0025
Brugia malayi Carboxylesterase family protein 0.0076 0.0198 0.059
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0118 0.0117
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0063 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.015 0.0318
Schistosoma mansoni glutaminase 0.0277 0.083 0.1402
Schistosoma mansoni opsin-like receptor 0.0086 0.0229 0.0384
Entamoeba histolytica zinc finger protein, putative 0.0032 0.0057 0.0433
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0014 0.0002 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0292 0.0292
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.0018
Echinococcus granulosus histone deacetylase 8 0.0151 0.0433 0.0731
Mycobacterium tuberculosis Conserved hypothetical protein 0.0049 0.0112 0.0236
Loa Loa (eye worm) histone deacetylase 1 0.0305 0.092 0.092
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0057 0.0138 0.0293
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0114 0.0318 0.0536
Echinococcus multilocularis acetylcholinesterase 0.0451 0.1381 0.2336
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0088 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0026 0.0106
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0026 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0277 0.0465
Loa Loa (eye worm) hypothetical protein 0.1074 0.3345 0.3345
Brugia malayi CHE-14 protein 0.0043 0.0092 0.0274
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0559 0.1721 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0051 0.0119 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0043 0.0095 0.0549
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0168 0.0486 0.0485
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0082 0.0087
Toxoplasma gondii 6-phosphofructokinase 0.0015 0.0006 0.0007
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0047 0.0107 0.011
Trypanosoma cruzi histone deacetylase 1, putative 0.0305 0.092 0.5347
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0234 0.0694 0.4035
Schistosoma mansoni histamine h1 receptor 0.0086 0.0229 0.0384
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0076 0.0198 0.0422
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0086 0.0229 0.0384
Brugia malayi glutaminase DH11.1 0.0277 0.083 0.248
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0043 0.0042
Brugia malayi sulfakinin receptor protein 0.0086 0.0229 0.0682
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Schistosoma mansoni neuropeptide F-like receptor 0.0086 0.0229 0.0384
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0096 0.0259 0.1508
Schistosoma mansoni gabp alpha 0.0073 0.0189 0.0316
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0006
Schistosoma mansoni chromatin regulatory protein sir2 0.0015 0.0004 0.0004
Echinococcus granulosus chromatin regulatory protein sir2 0.0015 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus poly (ADP ribose) polymerase 0.0132 0.0374 0.0632
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0086 0.0229 0.0228
Onchocerca volvulus 0.0086 0.0229 0.0948
Loa Loa (eye worm) hypothetical protein 0.0234 0.0694 0.0694
Onchocerca volvulus Tankyrase homolog 0.0032 0.0057 0.023
Echinococcus multilocularis neuropeptides capa receptor 0.0086 0.0229 0.0386
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0071 0.0118
Schistosoma mansoni netrin receptor unc5 0.0014 0.0003 0.0002
Onchocerca volvulus 0.005 0.0114 0.0468
Loa Loa (eye worm) hypothetical protein 0.0048 0.0108 0.0108
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.007 0.0178 0.0178
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0079 0.0205 0.1193
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.061 0.1881 0.1881
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0026 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0108 0.0112
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0029 0.005 0.0083
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0066 0.0276
Brugia malayi Muscleblind-like protein 0.1074 0.3345 1
Schistosoma mansoni hypothetical protein 0.0726 0.2247 0.38
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0031 0.0055 0.0091
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0043 0.0179
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0016 0.0016
Trichomonas vaginalis chromobox protein, putative 0.0086 0.0229 0.0956
Brugia malayi topoisomerase 0.0027 0.0043 0.0127
Brugia malayi Ets-domain containing protein 0.0073 0.0189 0.0562
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0011 0.0012
Brugia malayi G-protein coupled receptor 0.0086 0.0229 0.0682
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0182
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0071 0.0296
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0108 0.0322
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0026 0.004
Echinococcus granulosus peptide allatostatin:somatostatin 0.0086 0.0229 0.0386
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0063 0.0106
Echinococcus granulosus tachykinin peptides receptor 99D 0.0086 0.0229 0.0386
Echinococcus granulosus importin subunit beta 1 0.0057 0.0137 0.0232
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0116 0.0344
Brugia malayi Carboxylesterase family protein 0.0076 0.0198 0.059
Entamoeba histolytica phosphofructokinase, putative 0.0057 0.0138 0.1059
Schistosoma mansoni acetyl-CoA synthetase 0.0048 0.0108 0.018
Brugia malayi Serotonin receptor 0.0086 0.0229 0.0682
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.000000000041061
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.019 0.0321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0118 0.049
Brugia malayi Fli-1 protein 0.0223 0.0659 0.197
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0106
Echinococcus granulosus single minded 2 0.0036 0.0071 0.012
Echinococcus granulosus G protein coupled receptor 139 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.01 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0048 0.011 0.0109
Onchocerca volvulus 0.0048 0.0108 0.0445
Brugia malayi follicle stimulating hormone receptor 0.0086 0.0229 0.0682
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0182
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0189 0.0318
Trichomonas vaginalis rotamase, putative 0.0043 0.0095 0.0393
Trypanosoma brucei unspecified product 0.0034 0.0064 0.037
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0265 0.0792 0.4602
Echinococcus multilocularis chromobox protein 2 0.0014 0.0002 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.061 0.1881 0.3181
Onchocerca volvulus 0.0086 0.0229 0.0948
Leishmania major cytochrome p450-like protein 0.002 0.002 0.0116
Schistosoma mansoni tar DNA-binding protein 0.0152 0.0436 0.0735
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0029 0.0046
Trypanosoma cruzi cytochrome P450, putative 0.002 0.002 0.0116
Brugia malayi AKH receptor 0.0086 0.0229 0.0682
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0103 0.0431
Brugia malayi Dopamine receptor protein 1 0.0086 0.0229 0.0682
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0002 0.0009
Loa Loa (eye worm) heterochromatin protein 1 0.0086 0.0229 0.0229
Brugia malayi Carboxylesterase family protein 0.0076 0.0198 0.059
Echinococcus granulosus L aminoadipate semialdehyde 0.0051 0.0119 0.02
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0162 0.0169
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0028 0.0047 0.0138
Brugia malayi SWIRM domain containing protein 0.0047 0.0107 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Entamoeba histolytica histone deacetylase, putative 0.0305 0.092 0.7083
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus 6 phosphofructokinase 0.0057 0.0138 0.0233
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0265 0.0792 0.4602
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0048 0.0108 0.0229
Echinococcus granulosus pyruvate kinase 0.0033 0.0063 0.0105
Schistosoma mansoni hypothetical protein 0.1886 0.5909 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0076 0.0198 0.0332
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0057 0.0138 0.2706
Onchocerca volvulus 0.0086 0.0229 0.0948
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0071 0.012
Echinococcus granulosus intermediate filament protein 0.0027 0.0043 0.0071
Loa Loa (eye worm) hypothetical protein 0.0159 0.046 0.046
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0112 0.0332
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Trypanosoma cruzi cytochrome P450, putative 0.002 0.002 0.0116
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0027 0.0043 0.0127
Entamoeba histolytica Ran family GTPase 0.0031 0.0055 0.0416
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0121 0.0499
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0052 0.0216
Onchocerca volvulus 0.0027 0.0043 0.0173
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Leishmania major UDP-galactopyranose mutase 0.0047 0.0107 0.0619
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0407 0.0687
Mycobacterium tuberculosis Carboxylesterase LipT 0.0076 0.0198 0.0422
Plasmodium vivax histone deacetylase, putative 0.0358 0.1086 0.1153
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0057 0.0138 0.0293
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0026 0.0042
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0026 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0108 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0015 0.0005 0.0005
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.0029 0.0048
Loa Loa (eye worm) hypothetical protein 0.0207 0.0611 0.061
Echinococcus multilocularis tankyrase 0.0032 0.0057 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0274 0.046
Giardia lamblia Fructose-bisphosphate aldolase 0.0154 0.0444 0.4818
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0002 0.0002
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0092 0.0092
Echinococcus multilocularis neuropeptide receptor 0.0086 0.0229 0.0386
Schistosoma mansoni hypothetical protein 0.0024 0.0032 0.0051
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0003 0.0002
Entamoeba histolytica phosphofructokinase, putative 0.0057 0.0138 0.1059
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0043 0.0179
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.0029 0.0029
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0063 0.0255
Schistosoma mansoni chromatin regulatory protein sir2 0.0015 0.0004 0.0004
Loa Loa (eye worm) tnks protein 0.0032 0.0057 0.0057
Echinococcus multilocularis lamin dm0 0.0027 0.0043 0.0071
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0118 0.0198
Brugia malayi hypothetical protein 0.0027 0.0043 0.0127
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0014 0.0003 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0044 0.0181
Schistosoma mansoni acetylcholinesterase 0.0076 0.0198 0.0332
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0408 0.0687
Schistosoma mansoni hypothetical protein 0.0726 0.2247 0.38
Loa Loa (eye worm) hypothetical protein 0.0214 0.0633 0.0632
Brugia malayi Serotonin receptor 0.0086 0.0229 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Trypanosoma brucei unspecified product 0.0049 0.0112 0.0648
Brugia malayi hypothetical protein 0.0014 0.0002 0.0005
Giardia lamblia Histone deacetylase 0.0305 0.092 1
Mycobacterium ulcerans Sir2-like regulatory protein 0.0015 0.0004 0.0002
Trichomonas vaginalis flap endonuclease-1, putative 0.0014 0.0001 0.0001
Trichomonas vaginalis esterase, putative 0.0036 0.0071 0.0296
Echinococcus granulosus tankyrase 0.0032 0.0057 0.0095
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0086 0.0229 0.0386
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0118 0.0684
Brugia malayi polk-prov protein 0.0015 0.0005 0.0014
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0063 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0011 0.0045
Schistosoma mansoni smad1 5 8 and 0.0015 0.0005 0.0005
Schistosoma mansoni pyruvate kinase 0.0033 0.0063 0.0103
Schistosoma mansoni myst-related protein 0.0018 0.0014 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.003
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0189 0.0188
Brugia malayi Pre-SET motif family protein 0.01 0.0274 0.0816
Entamoeba histolytica deoxycytidyl transferase, putative 0.0049 0.0112 0.0855
Echinococcus multilocularis L aminoadipate semialdehyde 0.0051 0.0119 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0052 0.0216
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0086 0.0229 0.0228
Echinococcus multilocularis histone deacetylase 6 0.0358 0.1086 0.1838
Trypanosoma brucei chrX additional, unordered contigs 0.0015 0.0005 0.003
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0014 0.0002 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0163 0.0472 0.1015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0086 0.0229 0.0228
Toxoplasma gondii endonuclease IV APN 0.0077 0.02 0.0212
Brugia malayi Protein kinase domain containing protein 0.0015 0.0003 0.0008
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0112 0.0648
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0027 0.0043 0.0043
Brugia malayi Importin beta-1 subunit 0.0057 0.0137 0.0409
Echinococcus granulosus g protein coupled receptor 0.0086 0.0229 0.0386
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0015 0.0004 0.0025
Onchocerca volvulus 0.0086 0.0229 0.0948
Brugia malayi hypothetical protein 0.0022 0.0026 0.0075
Echinococcus multilocularis histone deacetylase 6 0.0358 0.1086 0.1838
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0002 0.0002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0086 0.0229 0.0228
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0026 0.0026
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0015 0.0004 0.0029
Schistosoma mansoni terminal deoxycytidyl transferase 0.0049 0.0112 0.0186
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0026 0.0042
Trichomonas vaginalis replication factor C large subunit, putative 0.0027 0.0043 0.0179
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0151 0.0433 0.0432
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0274 0.0291
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0121 0.0505
Trypanosoma brucei histone deacetylase 4 0.0358 0.1086 0.6313
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0029 0.005 0.0378
Echinococcus granulosus geminin 0.0726 0.2247 0.3802
Plasmodium vivax SET domain protein, putative 0.01 0.0274 0.029
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0283 0.0851 0.0901
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0033 0.0253
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0071 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0064 0.037
Schistosoma mansoni hypothetical protein 0.0041 0.0087 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Echinococcus multilocularis protein patched 0.0043 0.0092 0.0155
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.005 0.0288
Entamoeba histolytica hypothetical protein 0.0027 0.0043 0.0327
Mycobacterium ulcerans glutaminase 0.0277 0.083 0.0879
Trypanosoma cruzi FHA domain containing protein, putative 0.0027 0.0043 0.025
Trichomonas vaginalis hypothetical protein 0.0019 0.0016 0.0065
Echinococcus granulosus chromobox protein 1 0.0086 0.0229 0.0387
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0026 0.0075
Brugia malayi hypothetical protein 0.0159 0.046 0.1374
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0063 0.0106
Trypanosoma cruzi PAB1-binding protein , putative 0.007 0.0178 0.1035
Schistosoma mansoni kinase 0.0025 0.0037 0.006
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0015 0.0004 0.0006
Plasmodium vivax chorismate synthase 0.2998 0.9417 1
Brugia malayi neuropeptide F receptor 0.0086 0.0229 0.0682
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0425 0.1299 0.2195
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0154 0.0444 0.3412
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0015 0.0004 0.0025
Toxoplasma gondii chorismate synthase, putative 0.2998 0.9417 1
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0234 0.0694 0.4035
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.02 0.0596
Trichomonas vaginalis spcc417.12 protein, putative 0.0076 0.0198 0.0825
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0118 0.0684
Schistosoma mansoni opsin-like receptor 0.0086 0.0229 0.0384
Echinococcus multilocularis rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0026 0.0075
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0032 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0043 0.0179
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0015 0.0005 0.0007
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0086 0.0229 0.0386
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0048 0.0108 0.0112
Echinococcus multilocularis neuropeptide s receptor 0.0086 0.0229 0.0386
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0118 0.0684
Trypanosoma brucei SIR2-like protein 4, putative 0.0015 0.0004 0.0025
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0283 0.0851 0.0901
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Brugia malayi Carboxylesterase family protein 0.0076 0.0198 0.059
Schistosoma mansoni hypothetical protein 0.0041 0.0087 0.0145
Brugia malayi transcriptional regulator, Sir2 family protein 0.0015 0.0004 0.0011
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0071 0.012
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0472 0.1408
Echinococcus granulosus GPCR family 2 0.0034 0.0063 0.0106
Brugia malayi Ets-domain containing protein 0.0073 0.0189 0.0562
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0138 0.0576
Loa Loa (eye worm) helicase 0.0014 0.0002 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0041 0.0088 0.0146
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0137 0.0146
Schistosoma mansoni ran 0.0031 0.0055 0.0089
Trypanosoma cruzi histone deacetylase, putative 0.0151 0.0433 0.2515
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0026 0.0042
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0063 0.0261
Echinococcus granulosus allatostatin A receptor 0.0086 0.0229 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Toxoplasma gondii histone deacetylase HDAC5 0.0151 0.0433 0.046
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0015 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0236
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0255 0.0761 0.1287
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0024 0.0032 0.0033
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0114 0.0477
Onchocerca volvulus 0.0016 0.0006 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0049 0.0111 0.0462
Loa Loa (eye worm) CXXC zinc finger family protein 0.0153 0.0439 0.0438
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0113 0.0315 0.1314
Plasmodium vivax heterochromatin protein 1, putative 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0047 0.0107 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.011 0.0457
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0086 0.0229 0.0384
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Echinococcus granulosus mothers against decapentaplegic 5 0.0015 0.0005 0.0007
Echinococcus granulosus regulator of G protein signaling 7 0.0031 0.0054 0.009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.0071
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0043 0.0179
Brugia malayi beta-lactamase family protein 0.0036 0.0071 0.0211
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0265 0.0792 0.4602
Echinococcus multilocularis protein dispatched 1 0.0049 0.0111 0.0187
Onchocerca volvulus 0.0014 0.0002 0.000000064554
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.0117 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Trichomonas vaginalis histone deacetylase, putative 0.0305 0.092 0.3841
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0026 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0086 0.0229 0.0384
Brugia malayi Heterochromatin protein 1 0.0086 0.0229 0.0684
Entamoeba histolytica hypothetical protein 0.0018 0.0014 0.0104
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0048 0.0108 0.0112
Brugia malayi putative neuropeptide receptor NPR1 0.0086 0.0229 0.0682
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Onchocerca volvulus 0.0036 0.0071 0.029
Loa Loa (eye worm) hypothetical protein 0.0073 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0113 0.0315 0.0314
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0056 0.0132 0.077
Plasmodium vivax histone deacetylase 2, putative 0.0358 0.1086 0.1153
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0055 0.0317
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0047 0.0107 0.0225
Loa Loa (eye worm) TAR-binding protein 0.0152 0.0436 0.0435
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0018
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0016 0.0046
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0327 0.0989 0.1672
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0048 0.0108 0.0112
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0031 0.0055 0.0057
Schistosoma mansoni hypothetical protein 0.0086 0.0229 0.0384
Loa Loa (eye worm) hypothetical protein 0.0451 0.1381 0.138
Echinococcus multilocularis histone deacetylase 1 0.0305 0.092 0.1556
Echinococcus multilocularis dro:myosuppressin receptor 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.0122 0.0342 0.0341
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0071 0.0211
Leishmania major acetyl-CoA synthetase, putative 0.0048 0.0108 0.0629
Toxoplasma gondii histone deacetylase SIR2-like 0.0015 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Schistosoma mansoni biogenic amine (5HT) receptor 0.0086 0.0229 0.0384
Onchocerca volvulus 0.0048 0.0108 0.0445
Echinococcus multilocularis neuropeptides capa receptor 0.0086 0.0229 0.0386
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0063 0.0365
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0004 0.0004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0049 0.0112 0.0188
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Trichomonas vaginalis glucosylceramidase, putative 0.042 0.1281 0.5349
Echinococcus multilocularis muscleblind protein 1 0.1074 0.3345 0.566
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0163 0.0472 0.1015
Schistosoma mansoni neuropeptide receptor 0.0086 0.0229 0.0384
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Loa Loa (eye worm) proteasome 26S subunit 0.0022 0.0025 0.0025
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0014 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0052 0.0217
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0048 0.0108 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0061 0.0255
Onchocerca volvulus 0.0076 0.0198 0.0819
Leishmania major histone deacetylase, putative 0.0305 0.092 0.5347
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0118 0.0684
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0451 0.1381 0.2334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0042
Echinococcus granulosus sex peptide receptor 0.0086 0.0229 0.0386
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Brugia malayi intermediate filament protein 0.0027 0.0043 0.0126
Echinococcus multilocularis nibrin 0.0027 0.0043 0.0072
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0011 0.0064
Brugia malayi MH1 domain containing protein 0.0015 0.0005 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0305 0.092 0.3841
Schistosoma mansoni biogenic amine receptor 0.0086 0.0229 0.0384
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0122 0.0342 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.0006
Echinococcus multilocularis histone deacetylase 0.0358 0.1086 0.1838
Schistosoma mansoni neuroligin 3 (S09 family) 0.0076 0.0198 0.0332
Leishmania major DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.0071
Brugia malayi RNA binding protein 0.0152 0.0436 0.1301
Trichomonas vaginalis glutaminase, putative 0.0277 0.083 0.3465
Echinococcus granulosus biogenic amine 5HT receptor 0.0086 0.0229 0.0386
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0086 0.0229 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0873 0.3643
Schistosoma mansoni growth hormone secretagogue receptor 0.0086 0.0229 0.0384
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0029 0.005 0.0081
Schistosoma mansoni pyruvate kinase 0.0033 0.0063 0.0103
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0022 0.0025 0.0105
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0071 0.0296
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0138 0.0576
Mycobacterium ulcerans oxidoreductase 0.0047 0.0107 0.011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0408 0.1217
Onchocerca volvulus 0.0086 0.0229 0.0948
Trypanosoma cruzi DNA damage repair protein, putative 0.0015 0.0005 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0085 0.0353
Leishmania major DNA polymerase kappa, putative 0.0015 0.0005 0.003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0086 0.0229 0.0386
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0472 0.1408
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0162 0.0345
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0033 0.0194
Trypanosoma brucei histone deacetylase, putative 0.0358 0.1086 0.6313
Schistosoma mansoni chromobox protein 0.0086 0.0229 0.0385
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0111 0.0462
Echinococcus multilocularis tumor protein p63 0.0339 0.1027 0.1737
Loa Loa (eye worm) histone deacetylase 7A 0.0358 0.1086 0.1086
Echinococcus multilocularis dna polymerase kappa 0.0049 0.0112 0.0188
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0085 0.0494
Loa Loa (eye worm) melatonin receptor type 1A 0.0086 0.0229 0.0228
Echinococcus granulosus rhodopsin orphan GPCR 0.0086 0.0229 0.0386
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0026 0.004
Plasmodium vivax importin-beta 2, putative 0.0057 0.0137 0.0145
Loa Loa (eye worm) hypothetical protein 0.005 0.0114 0.0113
Schistosoma mansoni biogenic amine receptor 0.0086 0.0229 0.0384
Plasmodium falciparum ataxin-2 like protein, putative 0.007 0.0178 0.0189
Loa Loa (eye worm) neuropeptide F receptor 0.0086 0.0229 0.0228
Plasmodium vivax histone deacetylase, putative 0.0151 0.0433 0.0459
Plasmodium vivax histone deacetylase 1, putative 0.0305 0.092 0.0976
Echinococcus multilocularis mothers against decapentaplegic 5 0.0015 0.0005 0.0007
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0022 0.0025 0.0105
Echinococcus multilocularis dna polymerase eta 0.0049 0.0112 0.0188
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0152 0.0436 0.0435
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0057 0.0138 0.0803
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0002 0.000000000041061
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0086 0.0229 0.0384
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0031 0.003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0043 0.0042
Brugia malayi beta-lactamase family protein 0.0036 0.0071 0.0211
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0114 0.019
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0011 0.0045
Plasmodium vivax 6-phosphofructokinase, putative 0.0015 0.0006 0.0006
Onchocerca volvulus 0.0076 0.0198 0.0819
Echinococcus granulosus histone deacetylase 7 0.0358 0.1086 0.1838
Loa Loa (eye worm) histone deacetylase 0.0358 0.1086 0.1086
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0103 0.0601
Brugia malayi hypothetical protein 0.0047 0.0107 0.0317
Trypanosoma brucei DNA damage repair protein, putative 0.0015 0.0005 0.003
Trypanosoma cruzi histone deacetylase, putative 0.0358 0.1086 0.6313
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.0434 0.0433
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.015 0.0156
Trichomonas vaginalis Heterochromatin protein, putative 0.0014 0.0002 0.0006
Brugia malayi larval opioid receptor 0.0086 0.0229 0.0682
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0826 0.3448
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0031 0.0056 0.0094
Brugia malayi histone deacetylase 1 (HD1) 0.0305 0.092 0.2749
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0026 0.0106
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0003 0.0002
Mycobacterium tuberculosis Possible oxidoreductase 0.0047 0.0107 0.0225
Trypanosoma brucei poly(adp-ribose) polymerase 0.0234 0.0694 0.4035
Echinococcus granulosus neuropeptide receptor 0.0086 0.0229 0.0386
Schistosoma mansoni tsg101-related 0.0025 0.0036 0.0058
Giardia lamblia Pyruvate kinase 0.0017 0.0011 0.0118
Loa Loa (eye worm) hypothetical protein 0.0048 0.0108 0.0108
Brugia malayi Histone deacetylase family protein 0.0358 0.1086 0.3246
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.011 0.0305 0.0655
Brugia malayi Cytochrome P450 family protein 0.002 0.002 0.0058
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0113 0.0315 0.342
Echinococcus granulosus neuropeptide Y receptor 0.0086 0.0229 0.0386
Schistosoma mansoni neuropeptide F-like receptor 0.0086 0.0229 0.0384
Schistosoma mansoni DNA helicase recq1 0.0019 0.0016 0.0024
Brugia malayi hypothetical protein 0.0076 0.0198 0.059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0321 0.0688
Echinococcus multilocularis g protein coupled receptor 0.0086 0.0229 0.0386
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0272 0.0459
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0672 0.2078 0.2204
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0112 0.0648
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0113 0.0315 0.1314
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0027 0.0043 0.0087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0108 0.0229
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.0071
Mycobacterium ulcerans lipase LipD 0.0036 0.0071 0.0073
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0048 0.0108 0.0629
Entamoeba histolytica acyl-CoA synthetase, putative 0.0163 0.0472 0.3628
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0063 0.0106
Echinococcus granulosus lamin 0.0027 0.0043 0.0071
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0071 0.0073
Loa Loa (eye worm) neuropeptide F receptor 0.0086 0.0229 0.0228
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0086 0.0229 0.0386
Mycobacterium ulcerans hypothetical protein 0.002 0.0021 0.002
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0015 0.0004 0.0029
Mycobacterium ulcerans beta-lactamase 0.0036 0.0071 0.0073
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0063 0.0106
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.011 0.0451
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0015 0.0006 0.0024
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0063 0.0255
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0108 0.0322
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0107 0.0225
Loa Loa (eye worm) TYRA-2 protein 0.0086 0.0229 0.0228
Plasmodium vivax NAD-dependent deacetylase, putative 0.0015 0.0004 0.0004
Toxoplasma gondii LsmAD domain-containing protein 0.007 0.0178 0.0189
Loa Loa (eye worm) hypothetical protein 0.0076 0.0198 0.0197
Echinococcus multilocularis pyruvate kinase 0.0033 0.0063 0.0105
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0122 0.0342 0.036
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0104
Echinococcus granulosus hypothetical protein 0.0086 0.0229 0.0386
Echinococcus granulosus neuroligin 0.0076 0.0198 0.0334
Echinococcus granulosus neuropeptides capa receptor 0.0086 0.0229 0.0386
Leishmania major silent information regulator 2, putative 0.0015 0.0004 0.0025
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0272 0.2088
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0186 0.0556
Trypanosoma brucei histone deacetylase 2 0.0151 0.0433 0.2515
Loa Loa (eye worm) histone deacetylase 11 0.0151 0.0433 0.0432
Loa Loa (eye worm) hypothetical protein 0.0049 0.0112 0.0111
Brugia malayi G protein-coupled receptor F59B2.13 0.0086 0.0229 0.0682
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0003 0.0004
Toxoplasma gondii ABC1 family protein 0.0036 0.0071 0.0076
Echinococcus multilocularis acetylcholinesterase 0.0451 0.1381 0.2336
Loa Loa (eye worm) acetylcholinesterase 1 0.0451 0.1381 0.138
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0041 0.0087 0.0145
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0071 0.0148
Plasmodium vivax DNA repair protein REV1, putative 0.0015 0.0005 0.0005
Trypanosoma cruzi DNA repair protein, putative 0.0056 0.0132 0.077
Trichomonas vaginalis phosphofructokinase, putative 0.0015 0.0006 0.0024
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Brugia malayi ORL1-like opioid receptor 0.0086 0.0229 0.0682
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0071 0.0148
Leishmania major importin beta-1 subunit, putative 0.0046 0.0103 0.0601
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0154 0.0444 0.1851
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0008 0.0031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0092 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0086 0.0229 0.0384
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0077 0.0081
Trichomonas vaginalis antibiotic synthetase, putative 0.0048 0.0108 0.0451
Brugia malayi hypothetical protein 0.0086 0.0229 0.0682
Echinococcus multilocularis BC026374 protein (S09 family) 0.0076 0.0198 0.0334
Echinococcus multilocularis geminin 0.0726 0.2247 0.3802
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0108 0.0229
Onchocerca volvulus 0.0159 0.046 0.1915
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0103 0.0431
Schistosoma mansoni chromatin regulatory protein sir2 0.0015 0.0004 0.0004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0077 0.0318
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0154 0.0444 0.3412
Schistosoma mansoni lamin 0.0027 0.0043 0.0069
Echinococcus granulosus poly (ADP ribose) polymerase 0.0066 0.0166 0.0279
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0015 0.0006 0.0069
Echinococcus multilocularis neuropeptide receptor A26 0.0086 0.0229 0.0386
Brugia malayi hypothetical protein 0.0164 0.0474 0.1415
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0018
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0255 0.0761 0.1287
Onchocerca volvulus 0.0086 0.0229 0.0948
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0559 0.1721 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0031 0.0055 0.0058
Loa Loa (eye worm) RecQ helicase 0.0045 0.01 0.0099
Brugia malayi Dopamine receptor 0.0086 0.0229 0.0682
Onchocerca volvulus 0.0163 0.0472 0.1962
Mycobacterium ulcerans chorismate synthase 0.2998 0.9417 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0111 0.0185
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0005 0.003
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0407 0.0687
Echinococcus granulosus para nitrobenzyl esterase 0.0076 0.0198 0.0334
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0071 0.0071
Schistosoma mansoni z-protein (S1r protein) 0.0031 0.0054 0.0088
Trichomonas vaginalis histone deacetylase, putative 0.0305 0.092 0.3841
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0026 0.0042
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0003 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0107 0.0113
Schistosoma mansoni 6-phosphofructokinase 0.0057 0.0138 0.0231
Echinococcus granulosus cpg binding protein 0.0161 0.0466 0.0788
Loa Loa (eye worm) hypothetical protein 0.0031 0.0054 0.0053
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0063 0.0261
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0162 0.0941
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0056 0.0132 0.077
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0163 0.0472 0.0498
Leishmania major acetyl-CoA synthetase, putative 0.0048 0.0108 0.0629
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0112 0.0648
Loa Loa (eye worm) hypothetical protein 0.0122 0.0342 0.0341
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0022 0.0025 0.0042
Schistosoma mansoni histone deacetylase 0.0305 0.092 0.1554
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0048 0.0108 0.0112
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0173 0.0503 1
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.02 0.0212
Giardia lamblia Transcriptional regulator, Sir2 family 0.0015 0.0004 0.004
Echinococcus multilocularis bloom syndrome protein 0.0045 0.01 0.0168
Loa Loa (eye worm) glutaminase 2 0.0277 0.083 0.083
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0086 0.0229 0.0384
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0015 0.0004 0.0017
Loa Loa (eye worm) histone methyltransferase 0.0051 0.0117 0.0117
Brugia malayi MH2 domain containing protein 0.0015 0.0005 0.0013
Entamoeba histolytica hypothetical protein 0.0022 0.0026 0.0193
Toxoplasma gondii proteasome regulatory subunit 0.0028 0.0047 0.005
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0026 0.0075
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0104
Brugia malayi Histone deacetylase 1 0.0305 0.092 0.2749
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0026 0.0106
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0118 0.0684
Onchocerca volvulus 0.0114 0.0318 0.1322
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.019 0.0321
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0016 0.0017
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0108 0.0112
Echinococcus multilocularis histone deacetylase 7 0.0358 0.1086 0.1838
Schistosoma mansoni alpha-1 adrenergic receptor 0.0086 0.0229 0.0384
Trichomonas vaginalis DNA polymerase eta, putative 0.0049 0.0112 0.0465
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0063 0.0186
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0086 0.0229 0.0228
Mycobacterium ulcerans hypothetical protein 0.0294 0.0886 0.0938
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0016 0.0017
Echinococcus multilocularis neuropeptide receptor 0.0086 0.0229 0.0386
Loa Loa (eye worm) hypothetical protein 0.0112 0.031 0.0309
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0071 0.0148
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0028 0.0047 0.0356
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0037 0.0073 0.0122
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0086 0.0229 0.0384

Activities

Activity type Activity value Assay description Source Reference
Agonistic effect (functional) = 17 % Rate of incorporation of [3H]-thymidine as evidence of mitogenetic activity ChEMBL. 11495580
Agonistic effect (functional) = 17 % Rate of incorporation of [3H]-thymidine as evidence of mitogenetic activity ChEMBL. 11495580
EC50 (functional) = 24 nM Intrinsic activity which is established by measuring the stimulation of mitogenesis ChEMBL. 11495580
EC50 (functional) = 24 nM Intrinsic activity which is established by measuring the stimulation of mitogenesis ChEMBL. 11495580
Ki (binding) = 3.1 nM Binding affinity against human dopamine receptor D4.4 using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 3.1 nM Binding affinity against human dopamine receptor D4.4 using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 4900 nM Binding affinity against dopamine receptor D3 using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 4900 nM Binding affinity against dopamine receptor D3 using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 7500 nM Binding affinity against dopamine receptor D1 using radioligand [3H]-SCH- 23390 ChEMBL. 11495580
Ki (binding) = 7500 nM Binding affinity against dopamine receptor D1 using radioligand [3H]-SCH- 23390 ChEMBL. 11495580
Ki (binding) = 13000 nM Binding affinity against dopamine receptor D2L using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 13000 nM Binding affinity against dopamine receptor D2L using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 15000 nM Binding affinity against dopamine receptor D2S using radioligand [3H]-spiperone ChEMBL. 11495580
Ki (binding) = 15000 nM Binding affinity against dopamine receptor D2S using radioligand [3H]-spiperone ChEMBL. 11495580

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11495580

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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