Detailed information for compound 1487124

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 380.439 | Formula: C25H20N2O2
  • H donors: 1 H acceptors: 2 LogP: 5.11 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1c(=O)/c(=N\CCc2ccccc2)/c2c3c1cccc3c(c1c2cccc1)O
  • InChi: 1S/C25H20N2O2/c1-27-20-13-7-12-19-21(20)22(17-10-5-6-11-18(17)24(19)28)23(25(27)29)26-15-14-16-8-3-2-4-9-16/h2-13,28H,14-15H2,1H3/b26-23-
  • InChiKey: YDOKUGZYPCUVEP-RWEWTDSWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens huntingtin Starlite/ChEMBL No references
Human herpesvirus 8 ORF 73 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Homo sapiens EYA transcriptional coactivator and phosphatase 2 Starlite/ChEMBL No references
Homo sapiens calcium channel, voltage-dependent, T type, alpha 1H subunit Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens Rap guanine nucleotide exchange factor (GEF) 3 Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Streptococcus pyogenes serotype M1 Streptokinase A Starlite/ChEMBL No references
Pseudomonas aeruginosa Beta Lactamase Starlite/ChEMBL No references
Homo sapiens glucosidase, alpha Starlite/ChEMBL No references
Homo sapiens core-binding factor, beta subunit No references
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references
Homo sapiens tumor susceptibility 101 Starlite/ChEMBL No references
Homo sapiens Rap guanine nucleotide exchange factor (GEF) 4 Starlite/ChEMBL No references
Homo sapiens runt-related transcription factor 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Pseudomonas aeruginosa Beta-lactamase Starlite/ChEMBL No references
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens toll-like receptor 9 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Salmonella choleraesuis (strain SC-B67) Beta-lactamase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_128950 All targets in OG5_128950
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis microtubule associated protein Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni eyes absent homolog Get druggable targets OG5_129664 All targets in OG5_129664
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania donovani transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog Get druggable targets OG5_131726 All targets in OG5_131726
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Onchocerca volvulus Get druggable targets OG5_133916 All targets in OG5_133916
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania braziliensis surface antigen-like protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania mexicana surface antigen-like protein Get druggable targets OG5_126560 All targets in OG5_126560
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania braziliensis surface antigen-like protein Get druggable targets OG5_126560 All targets in OG5_126560
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense nascent polypeptide associated complex alpha subunit, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Entamoeba histolytica pro protein convertase subtilisin/kexinType 5 precursor, putative Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania major surface antigen-like protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum IPR013091,EGF calcium-binding;IPR013111,EGF, extracellular;IPR001881,EGF-like calcium-binding;IPR006210,EGF;IPR000152,Aspartic a Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128950 All targets in OG5_128950
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus fibrillin 1 Get druggable targets OG5_126560 All targets in OG5_126560
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Giardia lamblia High cysteine membrane protein TMK-like Get druggable targets OG5_126560 All targets in OG5_126560
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis fibrillin 1 Get druggable targets OG5_126560 All targets in OG5_126560
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Class a beta-lactamase BlaC Get druggable targets OG5_143180 All targets in OG5_143180
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus microtubule associated protein Get druggable targets OG5_126560 All targets in OG5_126560
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Trypanosoma cruzi hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Cryptosporidium parvum BTF domain, basal transcription factor Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma cruzi hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis tumor susceptibility gene 101 protein Get druggable targets OG5_128950 All targets in OG5_128950
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Brugia malayi beta-NAC-like protein Get druggable targets OG5_127333 All targets in OG5_127333
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma cruzi transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Babesia bovis NAC domain containing protein Get druggable targets OG5_127333 All targets in OG5_127333
Giardia lamblia High cysteine membrane protein TMK-like Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) ICD-1 protein Get druggable targets OG5_127333 All targets in OG5_127333
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum Tumor susceptibility gene 101 protein, putative Get druggable targets OG5_128950 All targets in OG5_128950
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum ko:K01527 nascent polypeptide-associated complex subunit beta, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Giardia lamblia High cysteine non-variant cyst protein Get druggable targets OG5_126560 All targets in OG5_126560
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium knowlesi basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma mansoni tsg101-related Get druggable targets OG5_128950 All targets in OG5_128950
Trichomonas vaginalis DNA double-strand break repair Rad50 ATPase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus granulosus coiled coil domain containing protein 41 Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Brugia malayi hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Toxoplasma gondii NAC domain-containing protein Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_126560 All targets in OG5_126560
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K01187 alpha-glucosidase [EC3.2.1.20], putative Get druggable targets OG5_127055 All targets in OG5_127055
Theileria parva transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Candida albicans similar to S. cerevisiae GAL4 enhancer protein EGD1 (YPL037C) subunit alpha of the nascent polypeptide-associated chaperone comp Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_129328 All targets in OG5_129328
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Mycobacterium ulcerans class a beta-lactamase, BlaC Get druggable targets OG5_143180 All targets in OG5_143180
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum IPR006209,EGF-like;IPR013091,EGF calcium-binding;IPR001881,EGF-like calcium-binding;IPR006210,EGF;IPR000152,Aspartic acid and as Get druggable targets OG5_126560 All targets in OG5_126560
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum Neurogenic locus notch protein homolog precursor, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) TK/FER protein kinase Get druggable targets OG5_126560 All targets in OG5_126560
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi hypothetical protein Get druggable targets OG5_128950 All targets in OG5_128950
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) Get druggable targets OG5_139595 All targets in OG5_139595
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Trichomonas vaginalis Involucrin, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129328 All targets in OG5_129328
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) glycosyl hydrolase family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi Glycosyl hydrolases family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica hypothetical protein, conserved Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania braziliensis surface antigen-like protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus granulosus transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Entamoeba histolytica cysteine surface protein, putative Get druggable targets OG5_126560 All targets in OG5_126560
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia High cysteine membrane protein TMK-like Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum ko:K01931 tumor suppressor protein 101 [EC:6.3.2.19], putative Get druggable targets OG5_128950 All targets in OG5_128950
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_126560 All targets in OG5_126560
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tsg101-related Get druggable targets OG5_128950 All targets in OG5_128950
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Candida albicans similar to S. cerevisiae GAL4 enhancer protein EGD1 (YPL037C) subunit alpha of the nascent polypeptide-associated chaperone comp Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis NAC domain protein Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Onchocerca volvulus Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis coiled coil domain containing protein 41 Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Onchocerca volvulus Get druggable targets OG5_127055 All targets in OG5_127055
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica cysteine surface protein, putative Get druggable targets OG5_126560 All targets in OG5_126560
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus tumor susceptibility gene 101 protein Get druggable targets OG5_128950 All targets in OG5_128950
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131726 All targets in OG5_131726
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_126560 All targets in OG5_126560
Candida albicans weak similarity to S. cerevisiae STP22 putative ubiquitin receptor, and to mouse tumor susceiptibility protein TSG101 Get druggable targets OG5_128950 All targets in OG5_128950
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans UDP-galactopyranose mutase Glf Get druggable targets OG5_139595 All targets in OG5_139595
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania infantum surface antigen-like protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi N-terminal motif family protein Get druggable targets OG5_131726 All targets in OG5_131726
Echinococcus multilocularis transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog Get druggable targets OG5_129328 All targets in OG5_129328
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii basic transcription factor 3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum ko:K01104 protein-tyrosine phosphatase [EC3.1.3.48], putative Get druggable targets OG5_129664 All targets in OG5_129664
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Trypanosoma brucei transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) Get druggable targets OG5_139595 All targets in OG5_139595
Leishmania infantum basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium falciparum basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium vivax basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica cysteine surface protein, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica tyrosine kinase, putative Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum Lysosomal alpha-glucosidase precursor, putative Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans weak similarity to S. cerevisiae STP22 putative ubiquitin receptor, and to mouse tumor susceiptibility protein TSG101 Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica CXXC-rich protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica cysteine surface protein, putative Get druggable targets OG5_126560 All targets in OG5_126560
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni notch Get druggable targets OG5_126560 All targets in OG5_126560
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126560 All targets in OG5_126560
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia High cysteine membrane protein Group 1 Get druggable targets OG5_126560 All targets in OG5_126560
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126560 All targets in OG5_126560
Schistosoma mansoni tsg101-related Get druggable targets OG5_128950 All targets in OG5_128950
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica tumor susceptibility gene 101 protein, putative Get druggable targets OG5_128950 All targets in OG5_128950
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Trypanosoma brucei beta lactamase Beta-lactamase   269 aa 263 aa 98.9 %
Giardia lamblia U5 small nuclear ribonucleoprotein 200 kDa helicase, putative RecQ helicase-like 649 aa 521 aa 19.8 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.0472 0.6958
Onchocerca volvulus 0.0033 0.033 0.0426
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0393 0.4457
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.2753 0.3555
Schistosoma mansoni cpg binding protein 0.0035 0.0361 0.0506
Brugia malayi Muscleblind-like protein 0.018 0.2511 0.3244
Loa Loa (eye worm) hypothetical protein 0.0148 0.2033 0.2625
Brugia malayi jmjC domain containing protein 0.0011 0.0017 0.0022
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0075 0.0092
Schistosoma mansoni hypothetical protein 0.0014 0.0058 0.0081
Onchocerca volvulus Alhambra homolog 0.0035 0.0369 0.0476
Echinococcus granulosus neuropeptide s receptor 0.0558 0.809 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0494 0.1209
Schistosoma mansoni hypothetical protein 0.0205 0.2869 0.4019
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0019 0.0134 0.0257
Trypanosoma cruzi glyoxalase II 0.0019 0.0134 0.0257
Brugia malayi AF-10 protein 0.0012 0.0019 0.0025
Entamoeba histolytica type A flavoprotein, putative 0.0019 0.0134 0.0876
Schistosoma mansoni hypothetical protein 0.0019 0.013 0.0183
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0019 0.0134 0.0188
Echinococcus granulosus segment polarity protein dishevelled 0.0021 0.0166 0.0205
Schistosoma mansoni jumonji domain containing protein 0.0092 0.1201 0.1683
Mycobacterium tuberculosis Conserved protein 0.0019 0.0134 0.0134
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0089 0.0115
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0193 0.0239
Schistosoma mansoni eyes absent homolog 0.0106 0.142 0.1989
Brugia malayi beta-NAC-like protein 0.0042 0.0472 0.061
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0203 0.025
Leishmania major hypothetical protein, conserved 0.003 0.0299 0.0571
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Loa Loa (eye worm) hypothetical protein 0.0085 0.111 0.1433
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0494 0.1209
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0075 0.0092
Leishmania major hypothetical protein, conserved 0.0019 0.0134 0.0257
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Leishmania major metallo-beta-lactamase family-like protein 0.0019 0.0134 0.0257
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0134 0.0173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0134 0.0173
Toxoplasma gondii exonuclease III APE 0.0023 0.0185 0.2095
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0203 0.0387
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0134 0.0134
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0089 0.0171
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0056 0.0679 0.1298
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0019 0.0134 0.0257
Echinococcus multilocularis glycoprotein Antigen 5 0.0014 0.0058 0.0071
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.7138 0.8824
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0023 0.0256
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0166 0.0214
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0217 0.028
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1977 0.2553
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.0472 0.0903
Loa Loa (eye worm) hypothetical protein 0.0106 0.142 0.1834
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0019 0.0134 0.0876
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0019 0.0134 0.0166
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0075 0.0092
Brugia malayi hypothetical protein 0.0535 0.7742 1
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0203 0.0262
Leishmania major hypothetical protein, conserved 0.0027 0.0246 0.047
Onchocerca volvulus 0.0019 0.0134 0.0173
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0562 0.1074
Brugia malayi CXXC zinc finger family protein 0.0035 0.0361 0.0466
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0089 0.0171
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.008 0.0099
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0015 0.0075 0.0105
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.0019 0.0134 0.1524
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.1533 0.198
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0029 0.0192
Brugia malayi ethe1-prov protein 0.0019 0.0134 0.0173
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0369 0.0517
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0097
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0075 0.0097
Echinococcus granulosus lysine specific demethylase 5A 0.0047 0.0541 0.0669
Trypanosoma brucei glucosidase, putative 0.0044 0.0494 0.0944
Schistosoma mansoni dishevelled 0.0021 0.0166 0.0233
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0019 0.0134 0.0166
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0056 0.0679 0.0839
Brugia malayi N-terminal motif family protein 0.0015 0.0075 0.0097
Brugia malayi RasGEF domain containing protein 0.0015 0.0075 0.0097
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.0019 0.0134 0.0173
Trichomonas vaginalis beta lactamase domain, putative 0.0019 0.0134 0.0329
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0075 0.0097
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0606 0.1159
Onchocerca volvulus Huntingtin homolog 0.0148 0.2033 0.2625
Echinococcus multilocularis phd:f box containing protein 0.0011 0.0017 0.0021
Loa Loa (eye worm) trypsin family protein 0.0014 0.0058 0.0075
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0193 0.0239
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0154 0.212 0.212
Schistosoma mansoni alpha-glucosidase 0.0169 0.2348 0.329
Brugia malayi jmjC domain containing protein 0.0047 0.0541 0.0699
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0738 0.0953
Trypanosoma cruzi hypothetical protein 0.0015 0.0075 0.0144
Loa Loa (eye worm) hypothetical protein 0.0016 0.0082 0.0106
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0954 0.1337
Treponema pallidum ATP-dependent DNA helicase 0.0012 0.0029 0.0433
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0299 0.339
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0019 0.0134 0.0173
Echinococcus granulosus eukaryotic initiation factor 4A 0.0056 0.0679 0.0839
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0075 0.0092
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.1551 0.1917
Entamoeba histolytica type A flavoprotein, putative 0.0019 0.0134 0.0876
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0056 0.0679 0.443
Schistosoma mansoni rotamase 0.004 0.0445 0.0623
Trichomonas vaginalis rotamase, putative 0.004 0.0445 0.1089
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0494 0.1209
Schistosoma mansoni hypothetical protein 0.0041 0.0457 0.064
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0089 0.0583
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0203 0.0496
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Brugia malayi Bromodomain containing protein 0.0093 0.1215 0.1569
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0048 0.0562 0.3664
Echinococcus multilocularis JmjC domain containing protein 4 0.0011 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0134 0.0173
Schistosoma mansoni ap endonuclease 0.0023 0.0185 0.0258
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0321 0.4579 0.4579
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0562 0.0694
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0021 0.0166 0.0233
Mycobacterium tuberculosis Possible hydrolase 0.0019 0.0134 0.0134
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.003 0.0058
Trypanosoma cruzi glyoxalase II 0.0019 0.0134 0.0257
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0048 0.0562 0.1074
Plasmodium vivax hypothetical protein, conserved 0.0014 0.005 0.0742
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0185 0.0228
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0089 0.0115
Brugia malayi Trypsin family protein 0.0014 0.0058 0.0075
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0071
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.0019 0.0134 0.0257
Trichomonas vaginalis apoptosis inducing factor, putative 0.0019 0.0134 0.0329
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0472 0.0903
Trichomonas vaginalis beta lactamase domain, putative 0.0019 0.0134 0.0329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0562 0.1376
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0048 0.0562 0.0725
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0087 0.0165
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0015 0.0075 0.0093
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0027 0.0246 0.047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0134 0.0173
Brugia malayi jmjC domain containing protein 0.0011 0.0017 0.0022
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.013 0.0161
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.5231 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0185 0.0353
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0185 0.2718
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0084 0.1089 0.1346
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0048 0.0562 0.0787
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0019 0.0134 0.0257
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0494 0.5605
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0166 0.0232
Echinococcus granulosus zinc phosphodiesterase 0.0019 0.0134 0.0166
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0057 0.0139
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0015 0.0075 0.0184
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0193 0.0193
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0075 0.0105
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0193 0.0193
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0942 0.1165
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0056 0.0679 0.1298
Leishmania major DNA polymerase eta, putative 0.0038 0.041 0.0784
Schistosoma mansoni hypothetical protein 0.0019 0.0134 0.0188
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0457 0.059
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0431 0.4889
Leishmania major metallo-beta-lactamase family protein-like protein 0.0019 0.0134 0.0257
Onchocerca volvulus 0.0014 0.0058 0.0075
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Brugia malayi eukaryotic initiation factor 4A 0.0056 0.0679 0.0877
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0089 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0494 0.0944
Loa Loa (eye worm) hypothetical protein 0.018 0.2511 0.3244
Loa Loa (eye worm) hypothetical protein 0.0016 0.0089 0.0115
Echinococcus multilocularis dna polymerase eta 0.0054 0.0647 0.08
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.049 0.0605
Trypanosoma brucei glyoxalase II 0.0019 0.0134 0.0257
Leishmania major eukaryotic initiation factor 4a, putative 0.0056 0.0679 0.1298
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0193 0.0193
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0696 0.0861
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0541 0.0759
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0094
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0193 0.0271
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0494 0.0638
Mycobacterium ulcerans hypothetical protein 0.0019 0.0134 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0087 0.0165
Echinococcus multilocularis Mastin 0.0014 0.0058 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0017 0.0022
Brugia malayi hypothetical protein 0.0182 0.2542 0.3283
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0075 0.0105
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.0019 0.0134 0.0257
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.1533 0.293
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0203 0.0387
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.0153 0.0189
Echinococcus multilocularis lysine specific demethylase 6a 0.0011 0.0017 0.0021
Onchocerca volvulus 0.0037 0.0393 0.0507
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0075 0.0092
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0056 0.0679 0.443
Echinococcus granulosus intermediate filament protein 0.0033 0.033 0.0408
Mycobacterium ulcerans hypothetical protein 0.0019 0.0134 0.0134
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0089 0.0219
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0134 0.0134
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0019 0.0134 0.0173
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0203 0.1322
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0075 0.0092
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0299 0.4397
Loa Loa (eye worm) RasGEF domain-containing protein 0.0015 0.0075 0.0097
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.0689
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.003 0.0058
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0017 0.0033
Schistosoma mansoni tsg101-related 0.007 0.0881 0.1235
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0369 0.4189
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0229 0.0296
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0494 0.3221
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0021 0.0166 0.0214
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0445 0.0574
Trypanosoma brucei ISWI complex protein 0.0018 0.0122 0.0233
Loa Loa (eye worm) intermediate filament protein 0.0033 0.033 0.0426
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0075 0.0105
Echinococcus granulosus Pleckstrin G protein interacting region 0.0021 0.0166 0.0205
Schistosoma mansoni hypothetical protein 0.0205 0.2869 0.4019
Mycobacterium ulcerans hypothetical protein 0.0019 0.0134 0.0134
Loa Loa (eye worm) RasGEF domain-containing protein 0.0015 0.0075 0.0097
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0606 0.1159
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0014 0.0058 0.0071
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0606 0.1159
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0541 0.0759
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.013 0.0161
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0203 0.0262
Trypanosoma cruzi ISWI complex protein 0.0018 0.0122 0.0233
Loa Loa (eye worm) hypothetical protein 0.0048 0.0562 0.0725
Schistosoma mansoni DNA helicase recq5 0.0024 0.0203 0.0284
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.013 0.0161
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0185 0.0452
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.041 0.0784
Toxoplasma gondii hypothetical protein 0.0059 0.0717 0.8146
Brugia malayi hypothetical protein 0.0084 0.1089 0.1406
Schistosoma mansoni alpha glucosidase 0.0044 0.0494 0.0692
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0017 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0193 0.0369
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0057 0.0692 0.4517
Brugia malayi RasGEF domain containing protein 0.0015 0.0075 0.0097
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0023 0.0147
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0075 0.0105
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0021 0.0166 0.0214
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0203 0.025
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0089 0.0219
Loa Loa (eye worm) hypothetical protein 0.0049 0.0575 0.0743
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0089 0.0171
Leishmania major cleavage and polyadenylation specificity factor, putative 0.0019 0.0134 0.0257
Onchocerca volvulus 0.0021 0.0166 0.0214
Schistosoma mansoni DNA polymerase eta 0.0054 0.0647 0.0907
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0369 0.4189
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0012 0.0019 0.0218
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.003 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.2924 0.7163
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0075 0.0105
Plasmodium falciparum JmjC domain-containing protein, putative 0.0011 0.0017 0.0251
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0185 0.0238
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0057 0.0108
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0094
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0185 0.0185
Brugia malayi hypothetical protein 0.003 0.0299 0.0386
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0185 0.1204
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0203 0.025
Echinococcus granulosus son of sevenless 1 0.0015 0.0075 0.0093
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0075 0.0097
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0075 0.0092
Brugia malayi hypothetical protein 0.0021 0.0166 0.0214
Loa Loa (eye worm) hypothetical protein 0.0084 0.1089 0.1406
Brugia malayi Trypsin-like protease protein 5 0.0014 0.0058 0.0075
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0185 0.0353
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0193 0.0474
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0134 0.0329
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.1533 0.1895
Echinococcus granulosus lamin 0.0033 0.033 0.0408
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0022
Echinococcus multilocularis lamin 0.0033 0.033 0.0408
Entamoeba histolytica hypothetical protein 0.0042 0.0472 0.3082
Brugia malayi intermediate filament protein 0.0033 0.033 0.0426
Echinococcus granulosus expressed protein 0.004 0.0445 0.055
Mycobacterium ulcerans hydrolase 0.0019 0.0134 0.0134
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.028 0.0346
Mycobacterium ulcerans glyoxalase II, GloB 0.0019 0.0134 0.0134
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.2396 0.4581
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0015 0.0075 0.0097
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.1533 0.1895
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0075 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0134 0.0329
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0369 0.0476
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0075 0.0105
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0185 0.2718
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0696 0.0861
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.2753 0.3555
Schistosoma mansoni alpha-glucosidase 0.0169 0.2348 0.329
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0056 0.0679 0.1664
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0012 0.0023 0.0332
Schistosoma mansoni bromodomain containing protein 0.0078 0.1006 0.141
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2753 0.3403
Schistosoma mansoni hypothetical protein 0.0019 0.0134 0.0188
Entamoeba histolytica transcription factor BTF3, putative 0.0042 0.0472 0.3082
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0738 0.0953
Echinococcus multilocularis peregrin 0.0038 0.0411 0.0508
Brugia malayi hypothetical protein 0.0021 0.0166 0.0214
Entamoeba histolytica hypothetical protein 0.0014 0.0057 0.037
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0494 0.061
Echinococcus granulosus zinc finger protein 0.0026 0.0227 0.0281
Loa Loa (eye worm) hypothetical protein 0.0053 0.0639 0.0825
Loa Loa (eye worm) DIX domain-containing protein 0.0021 0.0166 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0445 0.1089
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0134 0.0329
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0541 0.0699
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0153 0.0215
Trypanosoma brucei unspecified product 0.0016 0.0087 0.0165
Echinococcus multilocularis expressed protein 0.004 0.0445 0.055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0166 0.0214
Loa Loa (eye worm) RecQ helicase 0.0024 0.0203 0.0262
Trichomonas vaginalis beta lactamase domain, putative 0.0019 0.0134 0.0329
Trypanosoma brucei unspecified product 0.0023 0.0193 0.0369
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0134 0.0134
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Echinococcus granulosus JmjC domain containing protein 4 0.0011 0.0017 0.0021
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0185 0.0452
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0011 0.0017 0.0194
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0075 0.0092
Treponema pallidum ribonuclease Z 0.0019 0.0134 0.1977
Loa Loa (eye worm) hypothetical protein 0.0033 0.033 0.0426
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Brugia malayi jmjC domain containing protein 0.0011 0.0017 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0393 0.055
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0445 0.0574
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.3569 0.461
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Mycobacterium ulcerans hypothetical protein 0.0014 0.0058 0.0058
Brugia malayi MH2 domain containing protein 0.0144 0.1977 0.2553
Toxoplasma gondii hypothetical protein 0.0021 0.0166 0.1885
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0056 0.0679 0.1664
Plasmodium falciparum cytosolic glyoxalase II 0.0019 0.0134 0.1977
Schistosoma mansoni dishevelled 0.0021 0.0166 0.0233
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0015 0.0075 0.0097
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0015 0.0075 0.0093
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.1533 0.198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0431 0.0823
Brugia malayi Latrophilin receptor protein 2 0.0019 0.013 0.0169
Loa Loa (eye worm) hypothetical protein 0.0054 0.0647 0.0836
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Brugia malayi jmjC domain containing protein 0.0115 0.1551 0.2003
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0494 0.0638
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0393 0.055
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0075 0.0092
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.041 0.4656
Echinococcus granulosus transmembrane protease serine 3 0.0014 0.0058 0.0071
Plasmodium vivax RNA helicase-1, putative 0.0056 0.0679 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0081 0.0105
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0019 0.0037
Echinococcus granulosus phd:f box containing protein 0.0011 0.0017 0.0021
Echinococcus multilocularis segment polarity protein dishevelled 0.0021 0.0166 0.0205
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0019 0.0134 0.0876
Echinococcus multilocularis muscleblind protein 0.018 0.2511 0.3104
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0299 0.0571
Plasmodium falciparum eukaryotic initiation factor 4A 0.0056 0.0679 1
Plasmodium vivax unspecified product 0.0019 0.0134 0.1977
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0056 0.0679 0.0839
Brugia malayi Trypsin family protein 0.0014 0.0058 0.0075
Plasmodium vivax SET domain protein, putative 0.0037 0.0393 0.5781
Mycobacterium ulcerans lipoprotein LpqF 0.0154 0.212 0.212
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.0019 0.0134 0.0876
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0075 0.0183
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0193 0.1261
Entamoeba histolytica metallo-beta-lactamase family protein 0.0019 0.0134 0.0876
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0153 0.0215
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0038
Echinococcus granulosus dna polymerase eta 0.0054 0.0647 0.08
Giardia lamblia PHD finger protein 15 0.0035 0.0369 0.2407
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0097
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Echinococcus multilocularis ETHE1 protein 0.0019 0.0134 0.0166
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0193 0.0369
Schistosoma mansoni phosphatidylserine receptor 0.0011 0.0017 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0166 0.0214
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0203 0.0387
Loa Loa (eye worm) hypothetical protein 0.0056 0.0679 0.0877
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0262
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Onchocerca volvulus 0.0535 0.7742 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0089 0.0219
Onchocerca volvulus Putative hydrolase PNKD 0.0019 0.0134 0.0173
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0203 0.2983
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0075 0.0105
Echinococcus multilocularis lamin dm0 0.0033 0.033 0.0408
Schistosoma mansoni transcription factor btf3 0.0042 0.0472 0.0662
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0134 0.0134
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.0153 0.0189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0562 0.1376
Leishmania major DNA polymerase eta, putative 0.0054 0.0647 0.1237
Schistosoma mansoni hypothetical protein 0.0014 0.0058 0.0081
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0203 0.0496
Echinococcus multilocularis cpg binding protein 0.0039 0.0424 0.0525
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0185 0.2718
Loa Loa (eye worm) hypothetical protein 0.003 0.0299 0.0386
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0029 0.0056
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0203 0.2983
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.2684 0.2684
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.003 0.0345
Mycobacterium ulcerans hypothetical protein 0.0019 0.0134 0.0134
Brugia malayi PHD-finger family protein 0.0032 0.0322 0.0417
Loa Loa (eye worm) RasGEF domain-containing protein 0.0015 0.0075 0.0097
Brugia malayi PHD-finger family protein 0.0016 0.0082 0.0106
Schistosoma mansoni cpg binding protein 0.0039 0.0424 0.0595
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0075 0.0092
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.5231 1
Trypanosoma brucei unspecified product 0.0016 0.0087 0.0165
Brugia malayi metallo-beta-lactamase superfamily protein 0.0019 0.0134 0.0173
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0134 0.0134
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0089 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0494 0.0944
Schistosoma mansoni tsg101-related 0.007 0.0881 0.1235
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0494 0.0944
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.013 0.0169
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0089 0.0219
Plasmodium vivax JmjC domain containing protein 0.0011 0.0017 0.0251
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0011 0.0017 0.0024
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0056 0.0679 0.0839
Echinococcus granulosus GPCR family 2 0.0019 0.013 0.0161
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0011 0.0017 0.0033
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0185 0.1204
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0185 0.0353
Schistosoma mansoni hypothetical protein 0.0035 0.0369 0.0517
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0369 0.0456
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0051 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0075 0.0092
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0203 0.0262
Echinococcus granulosus glycoprotein Antigen 5 0.0014 0.0058 0.0071
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0203 0.23
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0134 0.0876
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0019 0.0134 0.0876
Entamoeba histolytica metallo-beta-lactamase family protein 0.0019 0.0134 0.0876
Echinococcus granulosus enteropeptidase 0.0014 0.0058 0.0071
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0019 0.0134 0.0166
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Entamoeba histolytica metallo-beta-lactamase family protein 0.0019 0.0134 0.0876
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.0019 0.0134 0.1524
Mycobacterium leprae POSSIBLE HYDROLASE 0.0019 0.0134 0.0134
Toxoplasma gondii NAC domain-containing protein 0.0042 0.0472 0.5364
Brugia malayi PHD-finger family protein 0.0035 0.0369 0.0476
Schistosoma mansoni hypothetical protein 0.0012 0.0019 0.0027
Trypanosoma cruzi ISWI complex protein 0.0018 0.0122 0.0233
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0494 0.1209
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0185 0.0228
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0015 0.0064 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0185 0.0353
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0015 0.0075 0.0093
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1977 0.2553
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0193 0.0369
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0081 0.0101
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0023 0.0032
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0019 0.0134 0.0166
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.003 0.0058
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0089 0.0171
Loa Loa (eye worm) hypothetical protein 0.0057 0.0696 0.0899
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Echinococcus multilocularis transmembrane protease serine 3 0.0014 0.0058 0.0071
Loa Loa (eye worm) runx1 0.0067 0.0839 0.1084
Loa Loa (eye worm) hypothetical protein 0.0106 0.142 0.1834
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0166 0.0205
Echinococcus granulosus geminin 0.0205 0.2869 0.3546
Schistosoma mansoni hypothetical protein 0.0019 0.013 0.0183
Echinococcus multilocularis muscleblind protein 1 0.018 0.2511 0.3104
Schistosoma mansoni zinc finger protein 0.0026 0.0227 0.0319
Chlamydia trachomatis ribonuclease Z 0.0019 0.0134 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0478 0.0591
Trypanosoma cruzi hypothetical protein 0.0015 0.0075 0.0144
Trichomonas vaginalis beta lactamase domain, putative 0.0019 0.0134 0.0329
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Trichomonas vaginalis ras GTP exchange factor, putative 0.0015 0.0075 0.0184
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0027 0.0035
Brugia malayi hypothetical protein 0.0014 0.0058 0.0075
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0203 0.025
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0562 0.1074
Echinococcus granulosus transcription factor btf3 0.0042 0.0472 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0472 0.1157
Brugia malayi N-terminal motif family protein 0.0436 0.6283 0.8116
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0021 0.0166 0.0214
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0075 0.0092
Echinococcus multilocularis musashi 0.0033 0.033 0.0408
Mycobacterium tuberculosis Conserved protein 0.0019 0.0134 0.0134
Onchocerca volvulus 0.0035 0.0361 0.0466
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0431 0.2809
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0185 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.2396 0.4581
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0015 0.0075 0.0105
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0688 1 1
Echinococcus multilocularis ras GTP exchange factor 0.0015 0.0075 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0019 0.0134 0.0173
Echinococcus granulosus segment polarity protein dishevelled 0.0021 0.0166 0.0205
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.013 0.0169
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0942 0.1165
Schistosoma mansoni protein phosphatase 2C 0.0011 0.0017 0.0024
Schistosoma mansoni tsg101-related 0.0057 0.0692 0.097
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0203 0.0496
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Schistosoma mansoni lamin 0.0033 0.033 0.0462
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.008 0.0099
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0027 0.0246 0.047
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0014 0.005 0.0742
Echinococcus granulosus peregrin 0.0038 0.0411 0.0508
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0134 0.0329
Toxoplasma gondii PHD-finger domain-containing protein 0.0012 0.0019 0.0218
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.5231 1
Schistosoma mansoni lozenge 0.0067 0.0839 0.1176
Echinococcus granulosus cpg binding protein 0.0039 0.0424 0.0525
Loa Loa (eye worm) hypothetical protein 0.018 0.2511 0.3244
Brugia malayi Trypsin family protein 0.0014 0.0058 0.0075
Schistosoma mansoni hypothetical protein 0.0019 0.013 0.0183
Echinococcus multilocularis segment polarity protein dishevelled 0.0021 0.0166 0.0205
Loa Loa (eye worm) hypothetical protein 0.0436 0.6283 0.8116
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Onchocerca volvulus 0.0182 0.2542 0.3283
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0019 0.0037
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.1533 0.198
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0056 0.0679 0.0951
Onchocerca volvulus 0.0033 0.033 0.0426
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Onchocerca volvulus Huntingtin homolog 0.0148 0.2033 0.2625
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0494 0.1209
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0015 0.0075 0.0144
Schistosoma mansoni cpg binding protein 0.0039 0.0424 0.0595
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0606 0.1159
Loa Loa (eye worm) hypothetical protein 0.0041 0.0457 0.059
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0019 0.0134 0.0257
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0738 0.0953
Mycobacterium tuberculosis Conserved protein 0.0019 0.0134 0.0134
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0048 0.0562 0.0787
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0696 0.0976
Entamoeba histolytica hypothetical protein 0.0015 0.0075 0.049
Brugia malayi hypothetical protein 0.0019 0.0134 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0472 0.1157
Mycobacterium ulcerans hypothetical protein 0.0192 0.2684 0.2684
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0494 0.1209
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.033 0.0426
Entamoeba histolytica hypothetical protein 0.0014 0.0057 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0562 0.1376
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0369 0.5433
Brugia malayi metallo-beta-lactamase superfamily protein 0.0019 0.0134 0.0173
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2753 0.3403
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0881 1
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0193 0.025
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0683 0.1672
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0203 0.0262
Brugia malayi hypothetical protein 0.002 0.0139 0.018
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Brugia malayi hypothetical protein 0.0106 0.142 0.1834
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.5231 1
Loa Loa (eye worm) hypothetical protein 0.0535 0.7742 1
Onchocerca volvulus 0.0114 0.1529 0.1974
Schistosoma mansoni hypothetical protein 0.0018 0.0122 0.0171
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0562 0.0694
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0431 0.0823
Loa Loa (eye worm) hypothetical protein 0.0035 0.0369 0.0476
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0772 0.1475
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0029 0.0433
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0107 0.0138
Onchocerca volvulus 0.0287 0.4082 0.5272
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0134 0.0329
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0056 0.0679 0.0679
Schistosoma mansoni ap endonuclease 0.0023 0.0185 0.0258
Echinococcus multilocularis transcription factor btf3 0.0042 0.0472 0.0584
Echinococcus multilocularis enteropeptidase 0.0014 0.0058 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0029 0.0041
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0299 0.4397
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0193 0.0271
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0014 0.0058 0.0071
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0688 1 1
Mycobacterium ulcerans hydrolase 0.0019 0.0134 0.0134
Wolbachia endosymbiont of Brugia malayi metallo-beta-lactamase superfamily hydrolase 0.0019 0.0134 0.674
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Brugia malayi Trypsin family protein 0.0014 0.0058 0.0075
Leishmania major DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Echinococcus multilocularis ubiquitin specific protease 41 0.0048 0.0562 0.0694
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0185 0.0238
Echinococcus granulosus muscleblind protein 0.018 0.2511 0.3104
Mycobacterium ulcerans Zn-dependent glyoxylase 0.0019 0.0134 0.0134
Onchocerca volvulus 0.0015 0.0075 0.0097
Loa Loa (eye worm) hypothetical protein 0.0535 0.7742 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.049 0.0605
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0029 0.0334
Brugia malayi Pre-SET motif family protein 0.0037 0.0393 0.0507
Mycobacterium ulcerans hydrolase 0.0019 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0014 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0075 0.0105
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0214 0.301 0.3888
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0299 0.0571
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.0019 0.0134 0.1977
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0019 0.0134 0.0257
Echinococcus granulosus lysine specific demethylase 6a 0.0011 0.0017 0.0021
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0056 0.0679 0.1664
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0075 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0494 0.1209
Entamoeba histolytica alkyl sulfatase, putative 0.0019 0.0134 0.0876
Onchocerca volvulus 0.0014 0.0058 0.0075
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0369 0.0456
Trichomonas vaginalis hypothetical protein 0.0041 0.0453 0.111
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0134 0.0329
Brugia malayi Bromodomain containing protein 0.0046 0.0532 0.0687
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0014 0.0058 0.0081
Mycobacterium ulcerans beta lactamase-like protein 0.0019 0.0134 0.0134
Brugia malayi RasGEF domain containing protein 0.0015 0.0075 0.0097
Entamoeba histolytica hypothetical protein 0.0014 0.0057 0.037
Mycobacterium leprae Beta-lactamase-like protein 0.0019 0.0134 0.0134
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0027 0.0034
Leishmania major eukaryotic initiation factor 4a, putative 0.0056 0.0679 0.1298
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0075 0.049
Schistosoma mansoni hypothetical protein 0.0494 0.7138 1
Echinococcus granulosus ETHE1 protein 0.0019 0.0134 0.0166
Onchocerca volvulus 0.0012 0.0032 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0087 0.0165
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0193 0.0474
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0166 0.0233
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0075 0.0183
Loa Loa (eye worm) ICD-1 protein 0.0042 0.0472 0.061
Onchocerca volvulus 0.0014 0.0058 0.0075
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0193 0.0239
Schistosoma mansoni jumonji domain containing protein 0.0011 0.0017 0.0024
Echinococcus multilocularis zinc phosphodiesterase 0.0019 0.0134 0.0166
Loa Loa (eye worm) hypothetical protein 0.0019 0.013 0.0169
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0015 0.0075 0.0105
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.809 1
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0166 0.0233
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0431 0.0823
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0299 0.4397
Mycobacterium tuberculosis Beta lactamase like protein 0.0019 0.0134 0.0134
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0647 0.1237
Schistosoma mansoni phd/f-box containing protein 0.0011 0.0017 0.0024
Echinococcus multilocularis GPCR, family 2 0.0019 0.013 0.0161
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0572 0.0708
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.0019 0.0134 0.0257
Giardia lamblia DINP protein human, muc B family 0.0023 0.0193 0.1261
Echinococcus granulosus jumonji domain containing 1A 0.0011 0.0017 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0075 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0572 0.0708
Schistosoma mansoni zinc phosphodiesterase 0.0019 0.0134 0.0188
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0166 0.0205
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.013 0.0161
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0022
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0056 0.0679 0.1298
Trypanosoma brucei beta lactamase 0.0154 0.212 0.4052
Brugia malayi hypothetical protein 0.0148 0.2033 0.2625
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0696 0.0976
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.028 0.0346
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0494 0.061
Echinococcus granulosus dna polymerase kappa 0.0023 0.0193 0.0239
Loa Loa (eye worm) hypothetical protein 0.0182 0.2542 0.3283
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.1533 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Onchocerca volvulus 0.0014 0.0058 0.0075
Trypanosoma brucei polo-like protein kinase 0.0114 0.1533 0.293
Treponema pallidum ATP-dependent RNA helicase 0.0056 0.0679 1
Echinococcus granulosus ras GTP exchange factor 0.0015 0.0075 0.0093
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0166 0.0214
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0048 0.0562 0.3664
Trichomonas vaginalis rotamase, putative 0.0039 0.0431 0.1055
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0051 0.0063
Schistosoma mansoni kinase 0.0058 0.0705 0.0987
Schistosoma mansoni lamin 0.0033 0.033 0.0462
Giardia lamblia Sgs1 DNA helicase, putative 0.0024 0.0203 0.1322
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0017 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0393 0.0485
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0203 0.23
Echinococcus granulosus dnaJ subfamily B 0.0494 0.7138 0.8824
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0017 0.0022
Trichomonas vaginalis set domain proteins, putative 0.0287 0.4082 1
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.1533 0.2147
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1533 0.293
Echinococcus granulosus lamin dm0 0.0033 0.033 0.0408
Trichomonas vaginalis ras GTP exchange factor, putative 0.0015 0.0075 0.0184
Loa Loa (eye worm) hypothetical protein 0.006 0.0738 0.0953
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.028 0.0393
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0015 0.0075 0.0097
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0299 0.0571
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0057 0.0108
Echinococcus multilocularis Protein son of sevenless 0.0015 0.0075 0.0093
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0056 0.0679 0.0951
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0029 0.0056
Mycobacterium tuberculosis Possible hydrolase 0.0019 0.0134 0.0134
Brugia malayi Bromodomain containing protein 0.0038 0.0411 0.0531
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0097
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0107 0.0138
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0922 0.1191
Giardia lamblia Kinase, PLK 0.0114 0.1533 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0562 0.1074
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Echinococcus granulosus Mastin 0.0014 0.0058 0.0071
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.0647 0.1237
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0562 0.0694
Entamoeba histolytica alkyl sulfatase, putative 0.0019 0.0134 0.0876
Echinococcus granulosus ubiquitin specific protease 41 0.0048 0.0562 0.0694
Schistosoma mansoni intermediate filament proteins 0.0033 0.033 0.0462
Brugia malayi N-terminal motif family protein 0.0015 0.0075 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0472 0.1157
Leishmania major basic transcription factor 3a, putative 0.0042 0.0472 0.0903
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1533 0.3755
Echinococcus multilocularis jumonji domain containing 1A 0.0011 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0214 0.301 0.3888
Plasmodium falciparum phd finger protein, putative 0.0035 0.0369 0.5433
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0015 0.0075 0.0093
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0362 0.0447
Schistosoma mansoni zinc phosphodiesterase 0.0019 0.0134 0.0188
Echinococcus multilocularis son of sevenless 1 0.0015 0.0075 0.0093
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0056 0.0679 0.0877
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0075 0.0092
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.0019 0.0134 0.0257
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0193 0.025
Leishmania major hypothetical protein, conserved 0.0011 0.0017 0.0033
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0015 0.0075 0.0184
Entamoeba histolytica hypothetical protein 0.0014 0.0057 0.037
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0014 0.0058 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0494 0.1209
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.0019 0.0134 0.0173
Trichomonas vaginalis beta lactamase domain, putative 0.0019 0.0134 0.0329
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0014 0.0058 0.0075
Schistosoma mansoni hypothetical protein 0.0019 0.0134 0.0188
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0436 0.6283 0.8116
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0075 0.0105
Schistosoma mansoni hypothetical protein 0.0025 0.0217 0.0304
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0019 0.0134 0.0257
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0494 0.1209
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0011 0.0017 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0683 0.1672
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0472 0.0903
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0089 0.0219
Onchocerca volvulus 0.0014 0.0058 0.0075
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0027 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0193 0.0369
Trypanosoma cruzi glyoxalase II 0.0019 0.0134 0.0257
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1533 0.293
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0647 0.0836
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0494 0.3221
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0431 0.0823
Echinococcus multilocularis geminin 0.0205 0.2869 0.3546
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0019 0.0134 0.0166
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.2396 0.4581
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0057 0.0139
Schistosoma mansoni cercarial elastase (S01 family) 0.0014 0.0058 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0075 0.0092
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0015 0.0075 0.0105
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0019 0.0134 0.0876
Schistosoma mansoni dep domain containing protein 0.0021 0.0166 0.0233
Schistosoma mansoni hypothetical protein 0.0019 0.013 0.0183
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.2753 0.3403
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0021 0.0166 0.0205
Schistosoma mansoni ras GTP exchange factor 0.0015 0.0075 0.0105
Trichomonas vaginalis beta lactamase domain, putative 0.0019 0.0134 0.0329
Onchocerca volvulus 0.0014 0.0058 0.0075
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0164 0.0212
Echinococcus granulosus Protein son of sevenless 0.0015 0.0075 0.0093
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0154 0.212 0.212
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0193 0.0369
Echinococcus multilocularis zinc finger protein 0.0026 0.0227 0.0281
Loa Loa (eye worm) hypothetical protein 0.006 0.074 0.0956
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0057 0.0108
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0089 0.0219
Brugia malayi DIX domain containing protein 0.0021 0.0166 0.0214
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0075 0.0097
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0014 0.0058 0.0071
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0056 0.0679 0.771
Brugia malayi jmjC domain containing protein 0.0011 0.0017 0.0022
Onchocerca volvulus 0.0019 0.0134 0.0173
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.809 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0166 0.0205
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.809 1
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.0472 0.6958
Trichomonas vaginalis A-type flavoprotein 0.0019 0.0134 0.0329
Schistosoma mansoni DNA helicase recq1 0.0024 0.0203 0.0284
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0081 0.0101
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0203 0.025
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0166 0.0205
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0019 0.0134 0.0166
Loa Loa (eye worm) hypothetical protein 0.0032 0.0321 0.0415
Schistosoma mansoni zinc finger protein 0.0018 0.0122 0.0171
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0134 0.0329
Loa Loa (eye worm) hypothetical protein 0.0148 0.2033 0.2625
Echinococcus granulosus bloom syndrome protein 0.0024 0.0203 0.025
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.033 0.0426
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0084 0.1089 0.1346
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.1551 0.1917
Loa Loa (eye worm) hypothetical protein 0.0021 0.0166 0.0214
Echinococcus multilocularis Protein lozenge 0.0067 0.0839 0.1038
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0321 0.4579 0.4579
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0361 0.0466
Leishmania major hypothetical protein, conserved 0.0018 0.0122 0.0233
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0075 0.0092
Brugia malayi Pre-SET motif family protein 0.0252 0.3569 0.461
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0562 0.0694

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) = 0.73 uM PUBCHEM_BIOASSAY: Inhibitors of Mycobacterium tuberculosis UDP-galactopyranose mutase (UGM) enzyme Measured in Biochemical System Using Plate Reader - 2105-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504439] ChEMBL. No reference
AC50 (binding) = 0.902 uM PUBCHEM_BIOASSAY: C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504431] ChEMBL. No reference
EC50 (functional) 1.6 uM PUBCHEM_BIOASSAY: Inhibitors of T-Type Calcium Channel. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID449739, AID463087, AID493021, AID493022, AID493023, AID493041, AID504579, AID504584, AID504619, AID504628] ChEMBL. No reference
EC50 (functional) = 8.855 um PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1662 (Primary HTS)] ChEMBL. No reference
EC50 (functional) > 150 um PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1902 (Retest at Dose), 1900 (Counter Screen), 1662 (Primary HTS)] ChEMBL. No reference
IC50 (binding) = 2.191 uM PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 5.416 uM PUBCHEM_BIOASSAY: Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251] ChEMBL. No reference
IC50 (binding) = 5.975 uM PUBCHEM_BIOASSAY: Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251] ChEMBL. No reference
IC50 (binding) = 9.238 uM PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 11.484 uM PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase. (Class of assay: confirmatory) ChEMBL. No reference
Max_Activity_Concent (functional) 26 uM PubChem BioAssay. Thermal shift assay to identify compound binding to Kelch domain of Keap1 protein Measured in Biochemical System Using RT-PCR - 2119-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 2.5902 uM PubChem BioAssay. qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101: Hit Validation. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.0131 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 3.7686 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter. (Class of assay: confirmatory) [Related pubchem assays: 2281 (Summary of qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a), 463106 (LOPAC Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a)] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) ), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] ChEMBL. No reference
Potency (binding) 19.9526 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5749 uM PubChem BioAssay. qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101: Hit Validation in TR assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485342, AID485388] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Saccharomyces cerevisiae ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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