Detailed information for compound 156071

Basic information

Technical information
  • TDR Targets ID: 156071
  • Name: tert-butyl N-[(2S)-3-methyl-1-oxopentan-2-yl] carbamate
  • MW: 215.289 | Formula: C11H21NO3
  • H donors: 1 H acceptors: 2 LogP: 2.18 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C[C@H](C(CC)C)NC(=O)OC(C)(C)C
  • InChi: 1S/C11H21NO3/c1-6-8(2)9(7-13)12-10(14)15-11(3,4)5/h7-9H,6H2,1-5H3,(H,12,14)/t8?,9-/m1/s1
  • InChiKey: YJAAJMSZVZJPOQ-YGPZHTELSA-N  


Substructure search Similarity search

Network

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Synonyms

  • tert-butyl N-[(1S)-1-formyl-2-methyl-butyl]carbamate
  • N-[(1S)-1-formyl-2-methylbutyl]carbamic acid tert-butyl ester
  • tert-butyl N-[(2S)-3-methyl-1-oxo-pentan-2-yl]carbamate
  • N-[(1S)-1-formyl-2-methyl-butyl]carbamic acid tert-butyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cathepsin K Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin K 329 aa 349 aa 33.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0032 0.0261
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0116 0.0488 0.0514
Echinococcus granulosus voltage gated potassium channel 0.0015 0.002 0.0018
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0014 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0116 0.0489 0.0716
Brugia malayi Matrixin family protein 0.0262 0.1161 0.1697
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0011 0.0003 0.001
Loa Loa (eye worm) LGC-31 protein 0.0238 0.1047 0.154
Mycobacterium ulcerans oxidoreductase 0.0032 0.0099 0.0392
Loa Loa (eye worm) fibroinase 0.0027 0.0076 0.0108
Onchocerca volvulus 0.0058 0.0218 0.0848
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0449 0.2022 0.202
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0032 0.0099 0.0395
Schistosoma mansoni biogenic amine (5HT) receptor 0.0481 0.2172 0.8012
Brugia malayi Cation transporter family protein 0.0238 0.1047 0.1531
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0092 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0092 0.0131
Brugia malayi G-protein coupled receptor 0.0116 0.0488 0.0712
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Schistosoma mansoni hypothetical protein 0.0297 0.1323 0.4881
Echinococcus multilocularis nervana 2 0.0021 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0099 0.0141
Brugia malayi Cathepsin L-like precursor 0.0018 0.0035 0.0048
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.0457 0.0666
Onchocerca volvulus 0.0032 0.0099 0.0377
Plasmodium falciparum cysteine proteinase falcipain 1 0.0014 0.0016 0.0352
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0018 0.0066
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0116 0.0488 0.1802
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0018 0.0017
Echinococcus granulosus aldo keto reductase 0.0032 0.0099 0.0096
Echinococcus granulosus nAChR subunit 0.0128 0.0542 0.054
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0308 0.137 0.5055
Brugia malayi Pre-SET motif family protein 0.0413 0.1857 0.2717
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0116 0.0488 0.1802
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0238 0.1047 0.1531
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0092 0.0131
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0033
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.0572
Echinococcus multilocularis cathepsin L 0.0014 0.0016 0.0014
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0116 0.0488 0.0486
Onchocerca volvulus Huntingtin homolog 0.0135 0.0573 0.2249
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0247 0.091
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0134 0.1178
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0561 0.2538 0.9361
Brugia malayi G-protein coupled receptor 0.0116 0.0488 0.0712
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0255 0.0372
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0018 0.0016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Schistosoma mansoni acetylcholinesterase 0.0011 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0017 0.0032 0.0119
Echinococcus multilocularis glycine receptor subunit beta 0.0238 0.1047 0.1105
Plasmodium vivax vivapain-2 0.0027 0.0076 0.1632
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Schistosoma mansoni sodium/chloride dependent transporter 0.0561 0.2538 0.9361
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0014 0.0016 0.0058
Schistosoma mansoni sodium-dependent amino acid transporter 0.0095 0.0391 0.1441
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.0391 0.0411
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0014 0.0015 0.0271
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.023 0.0241
Loa Loa (eye worm) hypothetical protein 0.0066 0.0255 0.0372
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0018 0.0022
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0198 0.0287
Onchocerca volvulus 0.011 0.0457 0.1791
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0021 0.0047 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0116 0.0488 0.0514
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Leishmania major GTP-binding protein, putative 0.0021 0.0046 0.0065
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0092 0.0131
Schistosoma mansoni nuclear receptor 0.0014 0.0018 0.0066
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.006 0.023 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0032 0.0261
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0238 0.1047 0.3863
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi Troponin T 0.0069 0.027 0.0393
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0053 0.0051
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0255 0.0267
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0003 0.0011
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0065
Loa Loa (eye worm) DR-78 0.0014 0.0018 0.0022
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0392 0.057
Brugia malayi Cathepsin L-like precursor 0.0027 0.0076 0.0108
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0026 0.0071 0.0101
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0038 0.0257
Onchocerca volvulus 0.0116 0.0488 0.1915
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0018 0.0023
Brugia malayi G protein-coupled receptor 0.0116 0.0488 0.0712
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.023 0.0241
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0238 0.1047 0.1045
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0032 0.0261
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0021 0.0047 0.0172
Schistosoma mansoni hypothetical protein 0.0116 0.0488 0.1802
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0069 0.027 0.1055
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0056 0.0079
Echinococcus multilocularis troponin i 0.0116 0.0489 0.0514
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) ACC-1 protein 0.0238 0.1047 0.154
Loa Loa (eye worm) hypothetical protein 0.0053 0.0198 0.0288
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0092 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Echinococcus granulosus tachykinin peptides receptor 99D 0.0116 0.0488 0.0486
Entamoeba histolytica cysteine protease, putative 0.0027 0.0076 0.0448
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0014 0.0015 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0032 0.0261
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.0569
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0263 0.1163 0.1161
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.0427 0.0626
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0027 0.0076 0.1903
Onchocerca volvulus 0.0032 0.0099 0.0377
Onchocerca volvulus 0.006 0.023 0.0896
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0116 0.0488 0.1802
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0014 0.0016 0.0058
Schistosoma mansoni cpg binding protein 0.0058 0.0218 0.0804
Echinococcus multilocularis neuropeptides capa receptor 0.0116 0.0488 0.0514
Brugia malayi glutaminase DH11.1 0.054 0.2443 0.3576
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0053 0.0054
Plasmodium falciparum T-complex protein 1 subunit beta 0.0026 0.0071 0.1761
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0134 0.0495
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0065
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.0391 0.1441
Plasmodium vivax importin-beta 2, putative 0.0028 0.008 0.1742
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.0427 0.1672
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0032 0.0119
Onchocerca volvulus 0.0021 0.0047 0.0172
Trichomonas vaginalis esterase, putative 0.004 0.0134 0.0542
Onchocerca volvulus 0.0018 0.0035 0.0126
Brugia malayi Calcitonin receptor-like protein seb-1 0.0301 0.1342 0.1962
Brugia malayi hypothetical protein 0.0095 0.0391 0.0569
Loa Loa (eye worm) hypothetical protein 0.0367 0.1646 0.2423
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.0427 0.3004
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Brugia malayi Cathepsin L-like precursor 0.0027 0.0076 0.0108
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0198 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) beta-lactamase 0.004 0.0134 0.0194
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0134 0.0193
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.002 0.0019
Brugia malayi Carboxylesterase family protein 0.0066 0.0255 0.037
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0134 0.0195
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0134 0.0139
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0027 0.0076 0.0078
Loa Loa (eye worm) ctsf protein 0.0027 0.0076 0.0108
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0032 0.0646
Onchocerca volvulus 0.011 0.0457 0.1791
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0076 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0092 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Onchocerca volvulus 0.0128 0.0542 0.2126
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0004 0.0015
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0449 0.2022 0.2977
Onchocerca volvulus 0.0116 0.0488 0.1915
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0194
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0238 0.1047 0.1531
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0033
Echinococcus granulosus nervana 2 0.0021 0.0047 0.0044
Schistosoma mansoni myosin xvIII 0.0116 0.0488 0.1802
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0449 0.2022 0.2959
Plasmodium vivax vivapain-3 0.0014 0.0016 0.0029
Echinococcus multilocularis neuropeptide receptor 0.0116 0.0488 0.0514
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0021 0.0047 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0092 0.0131
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0134 0.0194
Brugia malayi Carboxylesterase family protein 0.0066 0.0255 0.037
Brugia malayi nuclear hormone receptor 0.0014 0.0018 0.0023
Brugia malayi nuclear receptor RXR 0.0014 0.0018 0.0023
Onchocerca volvulus 0.0116 0.0488 0.1915
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0093
Onchocerca volvulus 0.0116 0.0488 0.1915
Brugia malayi RE15519p 0.0116 0.0488 0.0712
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.023 0.0228
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Echinococcus granulosus neuropeptide FF receptor 2 0.0116 0.0488 0.0486
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0041
Brugia malayi hypothetical protein 0.011 0.0457 0.0666
Loa Loa (eye worm) T-complex protein 1 0.0026 0.0071 0.01
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0092 0.0131
Loa Loa (eye worm) hypothetical protein 0.0049 0.0178 0.0259
Trypanosoma brucei C-8 sterol isomerase, putative 0.1482 0.6785 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0044 0.0042
Onchocerca volvulus 0.0238 0.1047 0.412
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0056 0.0386
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0004 0.0008
Echinococcus multilocularis cathepsin L cysteine protease 0.0027 0.0076 0.0078
Brugia malayi nuclear receptor NHR-67 0.0014 0.0018 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0032 0.0261
Echinococcus granulosus dnaJ subfamily B 0.0397 0.1781 0.178
Echinococcus multilocularis thyroid hormone receptor alpha 0.0158 0.0681 0.0718
Echinococcus granulosus nervana 2 0.0021 0.0047 0.0044
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.013 0.0524
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0466 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0014 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Echinococcus granulosus cpg binding protein 0.0061 0.0233 0.0231
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.021 0.0922 0.0973
Brugia malayi Hemopexin family protein 0.0154 0.0661 0.0965
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0047
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Brugia malayi RNA, U transporter 1 0.0079 0.0317 0.0461
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0032 0.0119
Loa Loa (eye worm) hypothetical protein 0.0403 0.1811 0.2666
Onchocerca volvulus 0.0027 0.0076 0.0288
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0198 0.0288
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0392 0.0412
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0047
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0032 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0116 0.0488 0.0514
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0238 0.1047 0.154
Mycobacterium ulcerans hydrolase 0.0132 0.0561 0.2286
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0014 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi nuclear receptor NHR-88 0.0014 0.0018 0.0023
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0028 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0527 0.1942
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0032 0.0261
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0092 0.0338
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0157 0.0579
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0021 0.0047 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0273 0.1209 0.1767
Loa Loa (eye worm) carboxylesterase 0.0066 0.0255 0.0372
Plasmodium falciparum cysteine proteinase falcipain 3 0.0027 0.0076 0.1903
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.026 0.0272
Giardia lamblia Kinase, PLK 0.0103 0.0427 0.3068
Plasmodium vivax unspecified product 0.0014 0.0016 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0032 0.0119
Onchocerca volvulus 0.0095 0.0391 0.153
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0134 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0016 0.0056
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0092 0.009
Echinococcus granulosus FTZ F1 alpha 0.003 0.0092 0.009
Echinococcus multilocularis neuropeptide Y receptor 0.0116 0.0488 0.0514
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0004 0.0015
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0178 0.026
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0004 0.0015
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0114
Brugia malayi follicle stimulating hormone receptor 0.0116 0.0488 0.0712
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0032 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Brugia malayi ecdysone receptor 0.0014 0.0018 0.0023
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0238 0.1047 0.1105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Loa Loa (eye worm) glutaminase 2 0.054 0.2443 0.3598
Echinococcus multilocularis serotonin receptor 0.0234 0.1033 0.109
Echinococcus multilocularis neuropeptides capa receptor 0.0116 0.0488 0.0514
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Leishmania major aldo-keto reductase-like protein 0.0032 0.0099 0.0142
Echinococcus multilocularis 0.0017 0.0032 0.0032
Plasmodium vivax vivapain-1 0.0014 0.0016 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.0427 0.0625
Brugia malayi Tachykinin-like peptides receptor 99D 0.0116 0.0488 0.0712
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0028 0.0026
Entamoeba histolytica hypothetical protein 0.0035 0.0113 0.0714
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0116 0.0488 0.0712
Schistosoma mansoni neurotransmitter gated ion channel 0.011 0.0457 0.1686
Loa Loa (eye worm) hypothetical protein 0.0257 0.1135 0.1669
Echinococcus multilocularis orexin receptor type 2 0.0116 0.0488 0.0514
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Echinococcus granulosus fmrfamide receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) hypothetical protein 0.0032 0.01 0.0144
Echinococcus granulosus 7TM GPCR rhodopsin 0.0116 0.0488 0.0486
Brugia malayi hypothetical protein 0.0032 0.0098 0.014
Toxoplasma gondii ABC1 family protein 0.004 0.0134 0.2849
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0238 0.1047 0.154
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0016 0.002
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0681 0.2514
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0035 0.0135
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0092 0.0131
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0032 0.0261
Plasmodium vivax vivapain-2 0.0027 0.0076 0.1632
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0032 0.0261
Echinococcus granulosus serotonin receptor 0.0116 0.0488 0.0486
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0095 0.0391 0.0411
Brugia malayi neuropeptide F receptor 0.0116 0.0488 0.0712
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0032 0.0119
Loa Loa (eye worm) G-protein coupled receptor 0.0116 0.0488 0.0716
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0011 0.0002 0.0008
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0255 0.0267
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0092 0.0131
Toxoplasma gondii hypothetical protein 0.0095 0.0391 0.8373
Echinococcus multilocularis aldo keto reductase 0.0032 0.0099 0.0102
Loa Loa (eye worm) solute carrier family 6 member 4 0.0561 0.2538 0.3737
Mycobacterium tuberculosis Conserved protein 0.004 0.0134 0.1178
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Schistosoma mansoni biogenic amine receptor 0.0116 0.0488 0.1802
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0011 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.1482 0.6785 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0116 0.0488 0.1802
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0092 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.008 0.1683
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.1137
Brugia malayi mbt repeat family protein 0.0052 0.0194 0.0281
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Schistosoma mansoni biogenic amine receptor 0.0116 0.0488 0.1802
Schistosoma mansoni troponin I 0.0116 0.0489 0.1803
Brugia malayi steroid hormone receptor 0.003 0.0092 0.0131
Echinococcus granulosus endonuclease exonuclease phosphatase 0.021 0.0922 0.092
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0116 0.0488 0.1802
Loa Loa (eye worm) hypothetical protein 0.0069 0.027 0.0394
Echinococcus multilocularis nervana 2 0.0021 0.0047 0.0047
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0004 0.0002
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0032 0.0119
Schistosoma mansoni amine GPCR 0.0116 0.0488 0.1802
Brugia malayi T-complex protein 1, beta subunit 0.0026 0.0071 0.01
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0027 0.0076 0.0108
Brugia malayi AKH receptor 0.0116 0.0488 0.0712
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0449 0.2022 0.2135
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0392 0.057
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0076 0.0448
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0027 0.0076 0.0303
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Schistosoma mansoni cytochrome P450 0.0017 0.0032 0.0119
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0092 0.009
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0308 0.137 0.5055
Loa Loa (eye worm) hypothetical protein 0.0135 0.0573 0.0841
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0042 0.0146 0.0538
Loa Loa (eye worm) hypothetical protein 0.0561 0.2538 0.3737
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0134 0.1178
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0112 0.0161
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0017
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0026 0.0071 0.0068
Brugia malayi hypothetical protein 0.011 0.0457 0.0666
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0032 0.0119
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0238 0.1047 0.3863
Echinococcus multilocularis aldo keto reductase 0.0032 0.0099 0.0102
Schistosoma mansoni neurotransmitter gated ion channel 0.0128 0.0542 0.1999
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) hypothetical protein 0.0066 0.0255 0.0372
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0134 0.0132
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0469 0.2113 0.3091
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Mycobacterium ulcerans hypothetical protein 0.004 0.0134 0.0538
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0014 0.0016 0.0058
Onchocerca volvulus 0.0052 0.0194 0.0752
Echinococcus granulosus geminin 0.0499 0.2254 0.2252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Echinococcus granulosus glycine receptor subunit beta 0.0238 0.1047 0.1045
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0027 0.0076 0.0303
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Echinococcus granulosus cathepsin L 0.0014 0.0016 0.0014
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0014 0.0015 0.0091
Onchocerca volvulus 0.0027 0.0076 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0194 0.0715
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.0391 0.0389
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0092 0.0131
Echinococcus granulosus acetylcholinesterase 0.0066 0.0255 0.0253
Loa Loa (eye worm) hypothetical protein 0.0015 0.002 0.0025
Brugia malayi hypothetical protein 0.0014 0.0018 0.0023
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0194 0.0192
Echinococcus granulosus orexin receptor type 2 0.0116 0.0488 0.0486
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.026 0.038
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0092 0.035
Schistosoma mansoni hypothetical protein 0.0206 0.0902 0.3327
Onchocerca volvulus 0.0116 0.0488 0.1915
Loa Loa (eye worm) cytochrome P450 0.0017 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0116 0.0488 0.0514
Onchocerca volvulus 0.0308 0.137 0.5395
Echinococcus granulosus neuropeptide s receptor 0.0116 0.0488 0.0486
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0032 0.0119
Onchocerca volvulus 0.0095 0.0391 0.153
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Schistosoma mansoni neuropeptide receptor 0.0116 0.0488 0.1802
Plasmodium vivax SET domain protein, putative 0.006 0.023 0.5727
Onchocerca volvulus Huntingtin homolog 0.0135 0.0573 0.2249
Echinococcus multilocularis G-protein coupled receptor, putative 0.0116 0.0488 0.0514
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0238 0.1047 0.1531
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.0391 0.1441
Giardia lamblia Fructose-bisphosphate aldolase 0.0311 0.1386 1
Echinococcus granulosus para nitrobenzyl esterase 0.0011 0.0003 0.0001
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.0427 0.0622
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0247 0.091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.023 0.0849
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0032 0.0099 0.0395
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0092 0.009
Trichomonas vaginalis set domain proteins, putative 0.047 0.212 0.8674
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0132 0.0561 0.0818
Trichomonas vaginalis aldo/keto reductase, putative 0.0032 0.0099 0.0395
Onchocerca volvulus 0.0027 0.0076 0.0288
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0134 0.0542
Brugia malayi cytochrome P450 0.0017 0.0032 0.0044
Schistosoma mansoni hypothetical protein 0.0095 0.0392 0.1444
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0032 0.0119
Brugia malayi hypothetical protein 0.0035 0.0113 0.0162
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0116 0.0488 0.0716
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) oxidoreductase 0.0032 0.0099 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0371 0.137
Schistosoma mansoni hypothetical protein 0.0397 0.1781 0.6571
Brugia malayi sulfakinin receptor protein 0.0116 0.0488 0.0712
Echinococcus multilocularis aldehyde reductase 0.0023 0.0056 0.0057
Onchocerca volvulus 0.0032 0.0099 0.0377
Leishmania major calcium-translocating P-type ATPase 0.0014 0.0015 0.0019
Onchocerca volvulus 0.0014 0.0018 0.0058
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0128 0.0542 0.0791
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0128 0.0542 0.0791
Schistosoma mansoni troponin t invertebrate 0.0144 0.0618 0.2279
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0134 0.1178
Schistosoma mansoni pol-related 0.0032 0.0099 0.0364
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.0391 0.1441
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0116 0.0488 0.1802
Mycobacterium ulcerans beta-lactamase 0.004 0.0134 0.0538
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0026 0.0025
Onchocerca volvulus 0.0116 0.0488 0.1915
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0134 0.0541
Brugia malayi putative neuropeptide receptor 0.0116 0.0488 0.0712
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0238 0.1047 0.1531
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0238 0.1047 0.1105
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Brugia malayi Cytochrome P450 family protein 0.0017 0.0032 0.0044
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0144 0.0618 0.2426
Plasmodium falciparum transporter, putative 0.0095 0.0391 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Entamoeba histolytica hypothetical protein 0.0035 0.0113 0.0714
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0194 0.0192
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0194
Schistosoma mansoni nAChR subunit 0.011 0.0457 0.1686
Brugia malayi Cation transporter family protein 0.0308 0.137 0.2004
Brugia malayi Nuclear hormone receptor-like 1 0.0258 0.1143 0.1671
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus multilocularis g protein coupled receptor 0.0116 0.0488 0.0514
Trypanosoma brucei prostaglandin f synthase 0.0032 0.0099 0.0142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0301 0.1342 0.1974
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Giardia lamblia TCP-1 chaperonin subunit beta 0.0026 0.0071 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0092 0.0131
Toxoplasma gondii exonuclease III APE 0.0019 0.0038 0.0765
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0021 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0518 0.234 0.3447
Toxoplasma gondii t-complex protein beta subunit 0.0026 0.0071 0.1475
Echinococcus multilocularis para nitrobenzyl esterase 0.0011 0.0003 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0247 0.091
Plasmodium falciparum amino acid transporter, putative 0.0095 0.0391 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0238 0.1047 0.1105
Loa Loa (eye worm) hypothetical protein 0.0135 0.0573 0.0841
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0099 0.0141
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0092 0.0338
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0014 0.0015 0.0019
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0076 0.0109
Plasmodium falciparum importin beta, putative 0.0028 0.008 0.201
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Trichomonas vaginalis cation-transporting ATPase, putative 0.0014 0.0015 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0116 0.0488 0.0514
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0014 0.0015 0.0013
Schistosoma mansoni neuropeptide receptor 0.0116 0.0488 0.1802
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.0076 0.0281
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0238 0.1047 0.3863
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.011 0.0457 0.0666
Mycobacterium tuberculosis Probable oxidoreductase 0.0032 0.0099 0.0857
Onchocerca volvulus 0.0021 0.0047 0.0172
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.0391 0.1441
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.026 0.0258
Echinococcus granulosus tar DNA binding protein 0.0064 0.0247 0.0245
Onchocerca volvulus 0.0027 0.0076 0.0288
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0032 0.0044
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.0391 0.1441
Loa Loa (eye worm) RNA binding protein 0.0064 0.0247 0.0359
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.011 0.0457 0.0455
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Echinococcus multilocularis cysteine protease 0.0027 0.0076 0.0078
Brugia malayi beta-lactamase family protein 0.004 0.0134 0.0194
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0028 0.0027
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.0391 0.0389
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0002
Echinococcus multilocularis glycine receptor subunit beta 0.0238 0.1047 0.1105
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0046 0.0952
Onchocerca volvulus 0.0308 0.137 0.5395
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0018 0.0066
Echinococcus granulosus peptide allatostatin:somatostatin 0.0116 0.0488 0.0486
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0093
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0238 0.1047 0.1531
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0028 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0032 0.0261
Onchocerca volvulus 0.0095 0.0391 0.153
Entamoeba histolytica aldose reductase, putative 0.0032 0.0099 0.0611
Loa Loa (eye worm) hypothetical protein 0.0469 0.2113 0.3111
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0038 0.0052
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0003 0.0011
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.8373
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0004 0.0002
Onchocerca volvulus 0.0108 0.0452 0.1771
Echinococcus granulosus aldo keto reductase 0.0032 0.0099 0.0096
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0238 0.1047 0.154
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Loa Loa (eye worm) hypothetical protein 0.0308 0.137 0.2016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0099 0.0141
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi hypothetical protein 0.0016 0.0026 0.0034
Treponema pallidum fructose-bisphosphate aldolase 0.0311 0.1386 0.5394
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0194 0.0715
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Brugia malayi nuclear receptor NHR-88 0.003 0.0092 0.0131
Plasmodium vivax hypothetical protein, conserved 0.004 0.0134 0.3182
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0011 0.0003 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0004 0.0015
Echinococcus granulosus g protein coupled receptor 0.0116 0.0488 0.0486
Toxoplasma gondii P-type ATPase4, putative 0.0014 0.0015 0.0271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0016 0.002
Echinococcus multilocularis neuroligin 0.0011 0.0003 0.0001
Onchocerca volvulus Troponin I homolog 0.0116 0.0489 0.1916
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0178 0.4535
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0071 0.0069
Entamoeba histolytica aldose reductase, putative 0.0032 0.0099 0.0611
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0018 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0116 0.0488 0.0514
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0016 0.0008
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0026 0.0071 0.0101
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0092 0.009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0116 0.0488 0.0514
Echinococcus multilocularis serotonin receptor 0.0234 0.1033 0.109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Onchocerca volvulus 0.0032 0.0099 0.0377
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0032 0.0119
Brugia malayi Cathepsin L-like precursor 0.0027 0.0076 0.0108
Schistosoma mansoni neurotransmitter gated ion channel 0.011 0.0457 0.1686
Brugia malayi Na,K-ATPase alpha subunit 0.0014 0.0015 0.0018
Schistosoma mansoni sodium/chloride dependent transporter 0.0096 0.0392 0.1447
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0038 0.0038
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0038 0.0914
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.011 0.0457 0.067
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0116 0.0488 0.0514
Brugia malayi Carboxylesterase family protein 0.0011 0.0003 0.0001
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0134 0.1178
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0014 0.0015 0.0271
Brugia malayi hypothetical protein 0.011 0.0457 0.0666
Brugia malayi hypothetical protein 0.0014 0.0018 0.0023
Echinococcus granulosus BC026374 protein S09 family 0.0011 0.0003 0.0001
Schistosoma mansoni amine GPCR 0.0116 0.0488 0.1802
Brugia malayi Matrixin family protein 0.0108 0.0452 0.0659
Onchocerca volvulus 0.047 0.212 0.8351
Echinococcus multilocularis oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 0.0144 0.0618 0.0651
Echinococcus multilocularis importin subunit beta 1 0.0028 0.008 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0371 0.137
Echinococcus multilocularis neuropeptide FF receptor 2 0.0116 0.0488 0.0514
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0076 0.0109
Schistosoma mansoni amine GPCR 0.0116 0.0488 0.1802
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi excitatory GABA receptor EXP-1A 0.0238 0.1047 0.1531
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0012 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0187 0.0757
Schistosoma mansoni biogenic amine receptor 0.0116 0.0488 0.1802
Leishmania major hypothetical protein, conserved 0.0049 0.0178 0.026
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0247 0.091
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0238 0.1047 0.3863
Mycobacterium leprae conserved hypothetical protein 0.004 0.0134 0.1648
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0112 0.0161
Echinococcus granulosus hypothetical protein 0.0032 0.0099 0.0096
Entamoeba histolytica aldose reductase, putative 0.0032 0.0099 0.0611
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0618 0.2804 0.2961
Brugia malayi Matrixin family protein 0.0108 0.0452 0.0659
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0403 0.1811 0.2666
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0134 0.0496
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0092 0.0095
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0542 0.057
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0116 0.0488 0.0486
Onchocerca volvulus Matrilysin homolog 0.0108 0.0452 0.1771
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0044 0.0044
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0064
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0134 0.0871
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0449 0.2022 0.2135
Echinococcus multilocularis neuropeptide s receptor 0.0116 0.0488 0.0514
Onchocerca volvulus 0.0116 0.0488 0.1915
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0092 0.0095
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.1781 0.1881
Brugia malayi hypothetical protein 0.0049 0.0178 0.0258
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0046 0.0841
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0108 0.0452 0.1667
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0194
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0003 0.0011
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0021 0.0047 0.0172
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0016 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0118 0.017
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0004 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0371 0.0541
Loa Loa (eye worm) hypothetical protein 0.0108 0.0452 0.0662
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0113 0.0111
Schistosoma mansoni ATPase 0.0014 0.0015 0.0054
Loa Loa (eye worm) hypothetical protein 0.0052 0.0194 0.0281
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.011 0.0457 0.0666
Echinococcus granulosus neuropeptide receptor 0.0116 0.0488 0.0486
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0032 0.0119
Schistosoma mansoni neuropeptide F-like receptor 0.0116 0.0488 0.1802
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0092 0.0131
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.0391 0.1441
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.0457 0.0666
Schistosoma mansoni intermediate filament proteins 0.0053 0.0198 0.0731
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0004 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Echinococcus multilocularis nAChR subunit 0.0238 0.1047 0.1105
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi beta-lactamase 0.004 0.0134 0.0194
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0014 0.0015 0.0019
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0032 0.0119
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0116 0.0488 0.0716
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0255 0.0253
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0134 0.0139
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0141 0.0139
Schistosoma mansoni acetylcholine receptor subunit beta 0.011 0.0457 0.1686
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Trypanosoma cruzi cysteine protease, putative 0.0014 0.0016 0.002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1118 1
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0014 0.0015 0.0048
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.011 0.0457 0.0481
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0004 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0116 0.0488 0.0712
Brugia malayi intermediate filament protein 0.0053 0.0198 0.0287
Echinococcus granulosus neuropeptide receptor A26 0.0116 0.0488 0.0486
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0032 0.0119
Schistosoma mansoni lamin 0.0053 0.0198 0.0731
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.026 0.1052
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0032 0.0044
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.8373
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.008 0.0115
Loa Loa (eye worm) matrixin family protein 0.0241 0.1061 0.156
Leishmania major cytochrome p450-like protein 0.0017 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0518 0.234 0.3447
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.092 0.4193 0.4429
Onchocerca volvulus 0.0116 0.0488 0.1915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Echinococcus multilocularis nervana 2 0.0021 0.0047 0.0047
Entamoeba histolytica cysteine proteinase 2 0.0014 0.0016 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0134 0.0496
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0112 0.0162
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Echinococcus multilocularis somatostatin receptor 0.0116 0.0488 0.0514
Echinococcus granulosus biogenic amine 5HT receptor 0.0481 0.2172 0.217
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0238 0.1047 0.1531
Schistosoma mansoni hypothetical protein 0.0116 0.0488 0.1802
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.026 0.0958
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0076 0.0109
Onchocerca volvulus 0.0053 0.0198 0.077
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.0653 0.2662
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0238 0.1047 0.1045
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.0076 0.0281
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0065
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.0391 0.0389
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.011 0.0457 0.067
Onchocerca volvulus 0.0116 0.0488 0.1915
Schistosoma mansoni hypothetical protein 0.0116 0.0488 0.1802
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0032 0.0261
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0032 0.0261
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0004 0.0002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0116 0.0488 0.1802
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0032 0.0119
Echinococcus multilocularis aldo keto reductase 0.0032 0.0099 0.0102
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0449 0.2022 0.202
Brugia malayi hypothetical protein 0.0016 0.0026 0.0034
Schistosoma mansoni hypothetical protein 0.0022 0.0053 0.0197
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0035 0.0129
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0238 0.1047 0.1045
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0014 0.0015 0.0048
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0227 0.033
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0032 0.0261
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0021 0.0047 0.0047
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0004 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0116 0.0488 0.0514
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0011 0.0002 0.0008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0238 0.1047 0.1531
Loa Loa (eye worm) hypothetical protein 0.0108 0.0452 0.0662
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Echinococcus granulosus cathepsin l cysteine peptidase 0.0027 0.0076 0.0074
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0038 0.0145
Giardia lamblia Aldose reductase 0.0032 0.0099 0.0696
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Trypanosoma cruzi cruzipain precursor, putative 0.0027 0.0076 0.0109
Echinococcus multilocularis nervana 2 0.0021 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0071 0.0072
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) hypothetical protein 0.0017 0.0032 0.0042
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0076 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0116 0.0488 0.1802
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0134 0.0538
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0134 0.0195
Onchocerca volvulus 0.0116 0.0488 0.1915
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0092 0.0131
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0413 0.1857 0.2734
Schistosoma mansoni aldo-keto reductase 0.0032 0.0099 0.0364
Loa Loa (eye worm) matrix metalloproteinase 0.0108 0.0452 0.0662
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Onchocerca volvulus 0.004 0.0134 0.0518
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0076 0.0109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0449 0.2022 0.2977
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0134 0.0542
Echinococcus multilocularis fmrfamide receptor 0.0116 0.0488 0.0514
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0134 0.0195
Schistosoma mansoni opsin-like receptor 0.0116 0.0488 0.1802
Echinococcus multilocularis fmrfamide receptor 0.0116 0.0488 0.0514
Echinococcus granulosus nervana 2 0.0021 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0193
Echinococcus granulosus intermediate filament protein 0.0053 0.0198 0.0196
Echinococcus granulosus snurportin 1 0.0297 0.1323 0.1321
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0116 0.0488 0.1915
Trichomonas vaginalis helicase, putative 0.0013 0.0012 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.026 0.2302
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0032 0.0261
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0032 0.0099 0.0142
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0032 0.0044
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Brugia malayi Dopamine receptor protein 1 0.0518 0.234 0.3425
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0178 0.4535
Loa Loa (eye worm) hypothetical protein 0.0198 0.0865 0.1271
Onchocerca volvulus 0.0561 0.2538 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0116 0.0488 0.1802
Mycobacterium tuberculosis Conserved protein 0.004 0.0134 0.1178
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0038 0.061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0238 0.1047 0.1045
Echinococcus granulosus neuropeptide Y receptor 0.0116 0.0488 0.0486
Echinococcus granulosus 7tm_1 domain containing protein 0.0116 0.0488 0.0486
Loa Loa (eye worm) histone methyltransferase 0.002 0.0044 0.0061
Echinococcus multilocularis cysteine protease 0.0027 0.0076 0.0078
Echinococcus multilocularis neuropeptide receptor 0.0116 0.0488 0.0514
Schistosoma mansoni gliotactin 0.0011 0.0003 0.0011
Onchocerca volvulus 0.0116 0.0488 0.1915
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0092 0.0338
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Onchocerca volvulus Matrix metalloproteinase homolog 0.0241 0.1061 0.4174
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0128 0.0542 0.0791
Brugia malayi Cathepsin L-like precursor 0.0018 0.0035 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.0258 0.1143 0.1671
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.008 0.0115
Schistosoma mansoni nuclear receptor 0.0014 0.0018 0.0066
Schistosoma mansoni troponin I 0.0116 0.0489 0.1803
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0004 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Brugia malayi G protein-coupled receptor F59B2.13 0.0116 0.0488 0.0712
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0038 0.0051
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0392 0.0389
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0027 0.0076 0.1903
Schistosoma mansoni hypothetical protein 0.0154 0.0661 0.2438
Onchocerca volvulus 0.0053 0.0198 0.077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0134 0.0195
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0134 0.0195
Trypanosoma brucei aldo-keto reductase, putative 0.0032 0.0099 0.0142
Brugia malayi Importin beta-1 subunit 0.0028 0.008 0.0114
Loa Loa (eye worm) hypothetical protein 0.019 0.0826 0.1214
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi Serotonin receptor 0.1491 0.6829 1
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0016 0.002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0116 0.0488 0.0712
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0247 0.0258
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0227 0.0238
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0032 0.0261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Plasmodium vivax amine transporter, putative 0.0095 0.0391 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0092 0.009
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0004 0.0003
Leishmania major cysteine peptidase A (CPA) 0.0027 0.0076 0.0109
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.002 0.0018
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0018 0.0016
Onchocerca volvulus 0.004 0.0134 0.0518
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0095 0.0391 0.0389
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0134 0.1178
Echinococcus granulosus importin subunit beta 1 0.0028 0.008 0.0078
Echinococcus granulosus lamin 0.0053 0.0198 0.0196
Schistosoma mansoni glutaminase 0.054 0.2443 0.9013
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0026 0.0071 0.026
Brugia malayi hypothetical protein 0.011 0.0457 0.0666
Entamoeba histolytica hypothetical protein 0.0023 0.0056 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.023 0.0849
Loa Loa (eye worm) hypothetical protein 0.0757 0.3444 0.5074
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0218 0.0317
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0403 0.1811 0.6682
Onchocerca volvulus 0.0116 0.0488 0.1915
Schistosoma mansoni neuropeptide f receptor 76f 0.0116 0.0488 0.1802
Schistosoma mansoni zinc finger protein 0.0014 0.0018 0.0066
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0014 0.0015 0.0013
Onchocerca volvulus 0.011 0.0457 0.1791
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0032 0.0044
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.8373
Schistosoma mansoni lamin 0.0053 0.0198 0.0731
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0194 0.0202
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Echinococcus multilocularis aldo keto reductase 0.0032 0.0099 0.0102
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Loa Loa (eye worm) GABA receptor subunit 0.0128 0.0542 0.0795
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.026 0.1052
Loa Loa (eye worm) serotonin transporter b 0.0561 0.2538 0.3737
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Trichomonas vaginalis aldo/keto reductase, putative 0.0032 0.0099 0.0395
Echinococcus multilocularis GPCR, family 2 0.0095 0.0392 0.0412
Echinococcus granulosus glycine receptor subunit beta 0.0238 0.1047 0.1045
Loa Loa (eye worm) oxidoreductase 0.0032 0.0099 0.0141
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0014 0.0015 0.0051
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0542 0.054
Loa Loa (eye worm) oxidoreductase 0.0032 0.0099 0.0141
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.0391 0.1441
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Loa Loa (eye worm) hypothetical protein 0.0561 0.2538 0.3737
Trichomonas vaginalis ran, putative 0.0021 0.0046 0.0181
Loa Loa (eye worm) hypothetical protein 0.0234 0.1033 0.1519
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0004 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0134 0.014
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0092 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0092 0.0131
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0227 0.0225
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0157 0.0579
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0134 0.0542
Trichomonas vaginalis cation-transporting ATPase, putative 0.0014 0.0015 0.0051
Brugia malayi Troponin T 0.0069 0.027 0.0393
Schistosoma mansoni aldo-keto reductase 0.0032 0.0099 0.0364
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.0391 0.1441
Brugia malayi CXXC zinc finger family protein 0.0058 0.0218 0.0316
Toxoplasma gondii aldose reductase, putative 0.0032 0.0099 0.2077
Brugia malayi GnHR receptor homolog 0.0116 0.0488 0.0712
Brugia malayi Serotonin receptor 0.0116 0.0488 0.0712
Mycobacterium leprae Probable lipase LipE 0.004 0.0134 0.1648
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0112 0.0162
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.011 0.0457 0.0666
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0018 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.013 0.0524
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0194
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0026 0.0071 0.026
Schistosoma mansoni opsin-like receptor 0.0116 0.0488 0.1802
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0113 0.0416
Echinococcus granulosus GPCR family 2 0.0095 0.0392 0.0389
Brugia malayi larval opioid receptor 0.0116 0.0488 0.0712
Echinococcus multilocularis lamin dm0 0.0053 0.0198 0.0207
Schistosoma mansoni neuropeptide receptor 0.0116 0.0488 0.1802
Brugia malayi mbt repeat family protein 0.0052 0.0194 0.0281
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0032 0.0119
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0116 0.0488 0.1802
Loa Loa (eye worm) troponin T 0.0069 0.027 0.0394
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Onchocerca volvulus Cathepsin L homolog 0.0027 0.0076 0.0288
Onchocerca volvulus 0.0128 0.0542 0.2126
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.0427 0.0425
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0014 0.0015 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0092 0.035
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0116 0.0488 0.0514
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.0427 0.0449
Loa Loa (eye worm) hypothetical protein 0.0561 0.2538 0.3737
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0134 0.0195
Leishmania major cytochrome p450-like protein 0.0035 0.0112 0.0162
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0056 0.022
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0099 0.0141
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0021 0.0047 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0092 0.0131
Echinococcus granulosus aldehyde reductase 0.0023 0.0056 0.0054
Brugia malayi cathepsin L-like precursor 0.0018 0.0035 0.0048
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0038 0.5
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0011 0.0002 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0076 0.0448
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0016 0.002
Brugia malayi Troponin T 0.0069 0.027 0.0393
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0227 0.0225
Schistosoma mansoni acetylcholine receptor-related 0.011 0.0457 0.1686
Echinococcus granulosus glycine receptor subunit alpha 1 0.0238 0.1047 0.1045
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0112 0.0162
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.002 0.0073
Onchocerca volvulus 0.0032 0.0099 0.0377
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0194
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.023 0.0849
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0014 0.0015 0.0019
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0018 0.0023
Schistosoma mansoni importin beta-1 0.0028 0.008 0.0296
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.0064
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.011 0.0457 0.0455
Brugia malayi conserved hypotetical protein 0.0014 0.0018 0.0023
Onchocerca volvulus Putative nachr subunit 0.0449 0.2022 0.7966
Echinococcus granulosus somatostatin receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0018 0.0022
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0018 0.0017
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0481 0.2172 0.2294
Schistosoma mansoni amine GPCR 0.0598 0.2711 1
Loa Loa (eye worm) hypothetical protein 0.0518 0.234 0.3447
Echinococcus granulosus biogenic amine 5HT receptor 0.0234 0.1033 0.1031
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.0826 0.3248
Brugia malayi beta-lactamase family protein 0.004 0.0134 0.0194
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.1386 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0134 0.0495
Entamoeba histolytica Ran family GTPase 0.0021 0.0046 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0014 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0052 0.0194 0.0281
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0403 0.1811 0.265
Echinococcus multilocularis BC026374 protein (S09 family) 0.0011 0.0003 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.026 0.0958
Onchocerca volvulus Cathepsin L homolog 0.0027 0.0076 0.0288
Brugia malayi Matrixin family protein 0.0108 0.0452 0.0659
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0255 0.0941
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0116 0.0488 0.1802
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0178 0.3797
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.0391 0.0389
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0043 0.006
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0095 0.0391 0.5
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0128 0.0542 0.1999
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0092 0.035
Trichomonas vaginalis spcc417.12 protein, putative 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Echinococcus multilocularis sex peptide receptor 0.0116 0.0488 0.0514
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0371 0.137
Loa Loa (eye worm) neuropeptide F receptor 0.0116 0.0488 0.0716
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0134 0.0542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Echinococcus granulosus neuropeptide receptor 0.0116 0.0488 0.0486
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0032 0.0119
Loa Loa (eye worm) troponin I 0.0116 0.0489 0.0716
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Onchocerca volvulus 0.0116 0.0488 0.1915
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Brugia malayi Cathepsin L-like precursor 0.0027 0.0076 0.0108
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.0391 0.1441
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0032 0.0261
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0371 0.039
Echinococcus granulosus nervana 2 0.0021 0.0047 0.0044
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0238 0.1047 0.1531
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0238 0.1047 0.1531
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0092 0.009
Brugia malayi Cathepsin L-like precursor 0.0027 0.0076 0.0108
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0134 0.0194
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0026 0.0095
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0038 0.0052
Schistosoma mansoni ran 0.0021 0.0046 0.0171
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Echinococcus granulosus glycine receptor subunit alpha 1 0.0238 0.1047 0.1045
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0238 0.1047 0.1105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0238 0.1047 0.1531
Brugia malayi N-terminal motif family protein 0.019 0.0826 0.1207
Schistosoma mansoni neuropeptide F-like receptor 0.0116 0.0488 0.1802
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0014 0.0015 0.0013
Leishmania major cytochrome p450-like protein 0.0017 0.0032 0.0044
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0011 0.0002 0.0008
Echinococcus multilocularis cathepsin L cysteine protease 0.0027 0.0076 0.0078
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0092 0.0338
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0116 0.0488 0.0514
Entamoeba histolytica hypothetical protein 0.0128 0.0542 0.3844
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0371 0.0543
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0238 0.1047 0.154
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Treponema pallidum sodium- and chloride- dependent transporter 0.0561 0.2538 1
Trichomonas vaginalis chaperonin, putative 0.0026 0.0071 0.028
Echinococcus granulosus aldo keto reductase 0.0032 0.0099 0.0096
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0038 0.0311
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0194 0.0281
Schistosoma mansoni BC026374 protein (S09 family) 0.0011 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Brugia malayi hypothetical protein 0.0069 0.027 0.0393
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0038 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0041
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0014 0.0015 0.0054
Schistosoma mansoni hypothetical protein 0.0499 0.2254 0.8314
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0134 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Loa Loa (eye worm) norepinephrine transporter 0.0561 0.2538 0.3737
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0116 0.0488 0.0514
Onchocerca volvulus 0.004 0.0134 0.0518
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0026 0.0071 0.026
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0065
Trichomonas vaginalis cation-transporting ATPase, putative 0.0014 0.0015 0.0051
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Onchocerca volvulus 0.0154 0.0661 0.2595
Onchocerca volvulus 0.0238 0.1047 0.412
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0092 0.0095
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.0653 1
Echinococcus multilocularis geminin 0.0499 0.2254 0.238
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0092 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0247 0.091
Echinococcus granulosus g-protein coupled receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) matrixin family protein 0.0262 0.1161 0.1707
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0038 0.0167
Loa Loa (eye worm) hypothetical protein 0.0132 0.0561 0.0823
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.026 0.555
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0187 0.0757
Onchocerca volvulus 0.0116 0.0488 0.1915
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0092 0.0131
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0371 0.039
Brugia malayi Carboxylesterase family protein 0.0011 0.0003 0.0001
Loa Loa (eye worm) melatonin receptor type 1A 0.0116 0.0488 0.0716
Brugia malayi putative neuropeptide receptor NPR1 0.0116 0.0488 0.0712
Schistosoma mansoni ap endonuclease 0.0019 0.0038 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0427 0.1574
Onchocerca volvulus 0.0116 0.0488 0.1915
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0041
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0099 0.0141
Onchocerca volvulus 0.0116 0.0488 0.1915
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0046 0.0047
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0116 0.0488 0.0716
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0095 0.0391 0.0389
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0095 0.0391 0.0411
Schistosoma mansoni biogenic amine (5HT) receptor 0.0234 0.1033 0.3811
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Echinococcus granulosus G protein coupled receptor 139 0.0116 0.0488 0.0486
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0116 0.0488 0.0514
Loa Loa (eye worm) hypothetical protein 0.006 0.0227 0.0331
Brugia malayi Troponin family protein 0.0116 0.0489 0.0713
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0238 0.1047 0.1531
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0427 0.0626
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.011 0.0457 0.0666
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0014 0.0015 0.0051
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0112 0.0447
Echinococcus multilocularis nAChR subunit 0.0128 0.0542 0.057
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0449 0.2022 0.202
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0128 0.0542 0.0791
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0227 0.0838
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0194 0.0715
Loa Loa (eye worm) hypothetical protein 0.0206 0.0902 0.1325
Echinococcus multilocularis snurportin 1 0.0297 0.1323 0.1396
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Echinococcus multilocularis cpg binding protein 0.0061 0.0233 0.0244
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0032 0.0119
Schistosoma mansoni nAChR subunit 0.0238 0.1047 0.3863
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0392 0.0573
Echinococcus multilocularis lamin 0.0053 0.0198 0.0207
Leishmania major importin beta-1 subunit, putative 0.0023 0.0056 0.0079
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0092 0.0338
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0116 0.0488 0.1802
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0032 0.0261
Echinococcus granulosus neuropeptide Y receptor 0.0116 0.0488 0.0486
Brugia malayi ecdysteroid receptor 0.003 0.0092 0.0131
Brugia malayi Carboxylesterase family protein 0.0011 0.0003 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0371 0.0369
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0787 0.3579 0.3781
Schistosoma mansoni ran 0.0021 0.0046 0.0171
Leishmania major cathepsin L-like protease 0.0027 0.0076 0.0109
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0032 0.0261
Brugia malayi nuclear receptor RXR 0.0016 0.0026 0.0034
Giardia lamblia Aldose reductase 0.0032 0.0099 0.0696
Schistosoma mansoni cpg binding protein 0.0061 0.0233 0.086
Mycobacterium ulcerans glutaminase 0.054 0.2443 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0018 0.0017
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0014 0.0015 0.0019
Trichomonas vaginalis aldo/keto reductase, putative 0.0032 0.0099 0.0395
Trichomonas vaginalis glutaminase, putative 0.054 0.2443 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Brugia malayi nuclear hormone receptor 0.003 0.0092 0.0131
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0116 0.0488 0.0712
Leishmania major C-8 sterol isomerase-like protein 0.1482 0.6785 1
Loa Loa (eye worm) TYRA-2 protein 0.0116 0.0488 0.0716
Echinococcus multilocularis G protein coupled receptor 139 0.0116 0.0488 0.0514
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0018 0.0017
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0134 0.1178
Loa Loa (eye worm) hypothetical protein 0.0095 0.0392 0.0573
Loa Loa (eye worm) hypothetical protein 0.0234 0.1033 0.1519
Onchocerca volvulus 0.0027 0.0076 0.0288
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0247 0.0359
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0038 0.0052
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0021 0.0047 0.0044
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0112 0.0161
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0134 0.0953
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0681 0.2514
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0014 0.0015 0.0019
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0032 0.0099 0.1071
Toxoplasma gondii cathepsin CPL 0.0027 0.0076 0.1594
Schistosoma mansoni hypothetical protein 0.0128 0.0542 0.1998
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0011 0.0002 0.0008
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0021 0.0047 0.0172
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0095 0.0391 0.0569
Brugia malayi Cathepsin L-like precursor 0.0027 0.0076 0.0108
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0004 0.0002
Onchocerca volvulus 0.0238 0.1047 0.412
Echinococcus multilocularis neuropeptide receptor A26 0.0116 0.0488 0.0514
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0026 0.0071 0.1486
Schistosoma mansoni hypothetical protein 0.0116 0.0488 0.1802
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0141 0.0147
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0194 0.0752
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.0653 0.5823
Leishmania major prostaglandin f synthase, putative 0.0032 0.0099 0.0142
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0247 0.0358
Trypanosoma cruzi aldo-keto reductase 0.0032 0.0099 0.0142
Brugia malayi hypothetical protein 0.0011 0.0003 0.0001
Brugia malayi hypothetical protein 0.0135 0.0573 0.0836
Schistosoma mansoni hypothetical protein 0.0095 0.0392 0.1444
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0004 0.0015
Echinococcus granulosus sex peptide receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) acetylcholine receptor protein 0.011 0.0457 0.067
Echinococcus granulosus serotonin transporter 0.0561 0.2538 0.2536
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Loa Loa (eye worm) oxidoreductase 0.0032 0.0099 0.0141
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0297 0.1323 0.1947
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0092 0.0131
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0134 0.0542
Echinococcus granulosus cathepsin l1 0.0027 0.0076 0.0074
Loa Loa (eye worm) hypothetical protein 0.0095 0.0391 0.0572
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0092 0.0131
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0092 0.0338
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0113 0.0117
Schistosoma mansoni coup transcription factor 0.003 0.0092 0.0338
Onchocerca volvulus Matrilysin homolog 0.0241 0.1061 0.4174
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0035 0.0148
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0371 0.0369
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0056 0.022
Brugia malayi neuropeptide F receptor 0.0116 0.0488 0.0712
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0095 0.0391 1
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0011 0.0003 0.0001
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0018 0.0023
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0194 0.0202
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0449 0.2022 0.2135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0016 0.0056
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Brugia malayi Cytochrome P450 family protein 0.0035 0.0112 0.0161
Echinococcus granulosus dro:myosuppressin receptor 0.0116 0.0488 0.0486
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0134 0.0541
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0035 0.0135
Brugia malayi RNA binding protein 0.0064 0.0247 0.0358
Brugia malayi Troponin I 0.0116 0.0489 0.0713
Trypanosoma brucei polo-like protein kinase 0.0103 0.0427 0.0626
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.023 0.0849
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0178 0.4352
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.002 0.0073
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0238 0.1047 0.1105
Onchocerca volvulus 0.0032 0.0099 0.0377
Brugia malayi Pre-SET motif family protein 0.006 0.023 0.0334
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0561 0.2538 0.3714
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0041
Echinococcus granulosus acetylcholinesterase 0.0066 0.0255 0.0253
Schistosoma mansoni cpg binding protein 0.0061 0.0233 0.086
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.1386 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0018 0.0016
Schistosoma mansoni troponin I 0.0116 0.0489 0.1803
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0016 0.0008
Echinococcus multilocularis musashi 0.0053 0.0198 0.0207
Leishmania major hypothetical protein, conserved 0.004 0.0134 0.0195
Echinococcus granulosus neuroligin 0.0011 0.0003 0.0001
Echinococcus granulosus allatostatin A receptor 0.0116 0.0488 0.0486
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0394 0.177 0.1868
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0018 0.0058
Brugia malayi Matrixin family protein 0.0108 0.0452 0.0659
Echinococcus granulosus glycine receptor subunit alpha 1 0.0238 0.1047 0.1045
Onchocerca volvulus 0.0116 0.0488 0.1915
Loa Loa (eye worm) hypothetical protein 0.0108 0.0452 0.0662
Echinococcus granulosus neuropeptides capa receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Brugia malayi Cation transporter family protein 0.0238 0.1047 0.1531
Trypanosoma cruzi cysteine proteinase, putative 0.0014 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0128 0.0542 0.0795
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0194
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0014 0.0015 0.0051
Echinococcus multilocularis serotonin transporter 0.0561 0.2538 0.268
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0018 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0116 0.0488 0.1802
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0032 0.0119
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Onchocerca volvulus Neuropeptide F receptor homolog 0.0116 0.0488 0.1915
Onchocerca volvulus 0.0027 0.0076 0.0288
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0018 0.0017
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0018 0.0016
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0238 0.1047 0.1531
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0026 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.0064
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0032 0.0119
Loa Loa (eye worm) cysteine protease 0.0027 0.0076 0.0108
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0116 0.0488 0.0486
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0018 0.0023
Echinococcus granulosus nAChR subunit 0.0238 0.1047 0.1045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.0569
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0092 0.0131
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0038 0.0036
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0116 0.0488 0.0486
Schistosoma mansoni histamine h1 receptor 0.0116 0.0488 0.1802
Brugia malayi tailless protein 0.0014 0.0018 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0488 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Echinococcus granulosus g protein coupled receptor 0.0116 0.0488 0.0486
Schistosoma mansoni neuropeptide receptor 0.0116 0.0488 0.1802
Brugia malayi Cathepsin L-like cysteine proteinase 0.0018 0.0035 0.0048
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0046 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0041
Schistosoma mansoni ATPase 0.0014 0.0015 0.0054
Loa Loa (eye worm) hypothetical protein 0.0116 0.0489 0.0716
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0014 0.0015 0.0051
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0132 0.0561 0.5001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Schistosoma mansoni kinase 0.0052 0.0193 0.0713
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0033
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Echinococcus granulosus cathepsin L cysteine proteinase 0.0027 0.0076 0.0074
Onchocerca volvulus 0.0014 0.0015 0.0046
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0263 0.1163 0.1227
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0026 0.0071 0.0407
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0116 0.0488 0.0486
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0238 0.1047 0.1531
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0004 0.0002
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0394 0.177 0.1768
Loa Loa (eye worm) G-protein coupled receptor 0.0116 0.0488 0.0716
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0238 0.1047 0.1045
Schistosoma mansoni adenoreceptor 0.0116 0.0488 0.1802
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.011 0.0457 0.0481
Brugia malayi Cytochrome P450 family protein 0.0035 0.0112 0.0161
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.011 0.0457 0.0481
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Echinococcus granulosus lamin dm0 0.0053 0.0198 0.0196
Schistosoma mansoni hypothetical protein 0.0116 0.0489 0.1803
Brugia malayi ORL1-like opioid receptor 0.0116 0.0488 0.0712
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0116 0.0488 0.0514
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0092 0.0131
Brugia malayi Cytochrome P450 family protein 0.0036 0.0118 0.017
Echinococcus granulosus cysteine protease 0.0014 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.0499 0.2254 0.8314
Schistosoma mansoni hypothetical protein 0.0095 0.0392 0.1444
Brugia malayi Carboxylesterase family protein 0.0011 0.0003 0.0001
Mycobacterium ulcerans lipase LipD 0.004 0.0134 0.0538
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0108
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0032 0.0261
Brugia malayi Dopamine receptor 0.0116 0.0488 0.0712
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0038 0.0052
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0092 0.009
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Toxoplasma gondii hypothetical protein 0.0095 0.0391 0.8373
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0018 0.0066
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0014 0.0015 0.0019
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0128 0.0542 0.1999
Brugia malayi hypothetical protein 0.0116 0.0488 0.0712
Loa Loa (eye worm) neuropeptide F receptor 0.0116 0.0488 0.0716
Brugia malayi hypothetical protein 0.011 0.0457 0.0666
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0021 0.0047 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0134 0.0538
Loa Loa (eye worm) troponin 0.0069 0.027 0.0394
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0116 0.0488 0.0486
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0092 0.0338
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0238 0.1047 0.1105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Echinococcus multilocularis dro:myosuppressin receptor 0.0116 0.0488 0.0514
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0092 0.0095
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0056 0.022
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0134 0.1178
Entamoeba histolytica hypothetical protein 0.0035 0.0113 0.0714
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0178 0.026
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0227 0.0238
Loa Loa (eye worm) hypothetical protein 0.0308 0.137 0.2016
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.026 0.1052
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.023 0.4911
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0018 0.0023
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Mycobacterium leprae PROBABLE HYDROLASE 0.0132 0.0561 0.8522
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0032 0.0099 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0488 0.1802
Echinococcus granulosus neuropeptides capa receptor 0.0116 0.0488 0.0486
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0026 0.0095
Brugia malayi Dopamine receptor protein 2 0.0116 0.0488 0.0712
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0021 0.0047 0.0172
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0902 0.1318
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0092 0.0095
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0014 0.0015 0.0013
Schistosoma mansoni nuclear hormone receptor 0.003 0.0092 0.0338
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0012 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0018 0.0017
Schistosoma mansoni nAChR subunit 0.011 0.0457 0.1686
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0238 0.1047 0.1531
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0238 0.1047 0.1531
Loa Loa (eye worm) ACC-1 protein 0.0238 0.1047 0.154
Schistosoma mansoni hypothetical protein 0.0095 0.0392 0.1444
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0427 0.0626
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.002 0.0019
Schistosoma mansoni ap endonuclease 0.0019 0.0038 0.0139
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0092 0.0338
Leishmania major T-complex protein 1, beta subunit, putative 0.0026 0.0071 0.0101
Trypanosoma cruzi cysteine proteinase, putative 0.0014 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.01
Echinococcus multilocularis allatostatin A receptor 0.0116 0.0488 0.0514
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0018 0.0022
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0099 0.0096
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0116 0.0488 0.0716
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0084 0.0119
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0134 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0488 0.0514
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0027 0.0076 0.0078
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0095 0.0391 0.0411
Echinococcus granulosus cathepsin L cysteine protease 0.0014 0.0016 0.0014
Onchocerca volvulus 0.003 0.0092 0.035
Echinococcus multilocularis g-protein coupled receptor 0.0116 0.0488 0.0514
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0427 0.1739
Loa Loa (eye worm) hypothetical protein 0.011 0.0457 0.067
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0247 0.0359
Schistosoma mansoni hypothetical protein 0.0035 0.0113 0.0416
Mycobacterium tuberculosis Conserved protein 0.004 0.0134 0.1178
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0018 0.0035 0.0048
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0141 0.0204
Loa Loa (eye worm) oxidoreductase 0.0032 0.0099 0.0141
Echinococcus granulosus tm gpcr rhodopsin 0.0116 0.0488 0.0486
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0038 0.0145
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0092 0.0095
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0011 0.0003 0.0001
Loa Loa (eye worm) MBCTL1 0.006 0.0227 0.0331
Echinococcus granulosus troponin i 0.0116 0.0489 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0076 0.0303
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0004 0.0002
Schistosoma mansoni transmemberane protein 0.0021 0.0047 0.0172
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0014 0.0015 0.0051
Entamoeba histolytica cysteine proteinase 1, putative 0.0014 0.0016 0.0008
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.0391 0.0411
Schistosoma mansoni troponin I 0.0116 0.0489 0.1803
Onchocerca volvulus 0.0014 0.0018 0.0058
Echinococcus granulosus oncosphere protein Tso22e 0.0144 0.0618 0.0616
Brugia malayi Melatonin receptor type 1A 0.0116 0.0488 0.0712
Onchocerca volvulus 0.0027 0.0076 0.0288
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0099 0.0395
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0258 0.1143 0.1681
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0131
Schistosoma mansoni amine GPCR 0.0116 0.0488 0.1802
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0016 0.0008
Echinococcus granulosus cathepsin l1 0.0018 0.0035 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0076 0.0109
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0618 0.2804 0.2802
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0032 0.0119
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.0391 0.0572
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Onchocerca volvulus Cathepsin F homolog 0.0027 0.0076 0.0288
Brugia malayi T-complex protein 1, beta subunit 0.0026 0.0071 0.01
Echinococcus granulosus alpha 1A adrenergic receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) glutaminase 0.054 0.2443 0.3598
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0014 0.0015 0.0323
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0038 0.0052
Trypanosoma cruzi aldo/keto reductase, putative 0.0032 0.0099 0.0142
Schistosoma mansoni opsin-like receptor 0.0116 0.0488 0.1802
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0018 0.0058
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0214 0.0212
Schistosoma mansoni neuroligin 3 (S09 family) 0.0011 0.0003 0.0011
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0004 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.092 0.4193 0.4191
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.1386 0.567
Echinococcus granulosus g protein coupled receptor 0.0116 0.0488 0.0486
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0238 0.1047 0.154
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0141 0.0204
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0319
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0092 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0022
Entamoeba histolytica hypothetical protein 0.0035 0.0113 0.0714
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0084 0.012
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0116 0.0488 0.0716
Brugia malayi TAR-binding protein 0.0064 0.0247 0.0358
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1482 0.6785 0.9935
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0134 0.0541
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0238 0.1047 0.1105
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1482 0.6785 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0134 0.0132
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0255 0.0267
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0076 0.0303
Schistosoma mansoni growth hormone secretagogue receptor 0.0116 0.0488 0.1802
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0018 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0116 0.0488 0.0716
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0178 0.026
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0014 0.0015 0.0017
Onchocerca volvulus 0.0308 0.137 0.5395
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0099 0.0102
Entamoeba histolytica cysteine protease, putative 0.0014 0.0016 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0016 0.002
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0026 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0238 0.1047 0.154
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0026 0.0071 0.028
Echinococcus multilocularis conserved hypothetical protein 0.2063 0.9463 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0092 0.0131
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0134 0.0195
Schistosoma mansoni hypothetical protein 0.0323 0.144 0.5311

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 250 nM Inhibiory activity against recombinant human cathepsin K ChEMBL. 14684342
IC50 (binding) = 250 nM Inhibiory activity against recombinant human cathepsin K ChEMBL. 14684342

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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