Detailed information for compound 1781445

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 324.344 | Formula: C14H16N10
  • H donors: 2 H acceptors: 7 LogP: 2.12 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNc1nc(nc(n1)n1cnc(n1)C#N)NC1(C#N)CCCCC1
  • InChi: 1S/C14H16N10/c1-17-11-19-12(22-14(8-16)5-3-2-4-6-14)21-13(20-11)24-9-18-10(7-15)23-24/h9H,2-6H2,1H3,(H2,17,19,20,21,22)
  • InChiKey: JCCIVCCBHFWGDN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens phosphodiesterase 7A Starlite/ChEMBL References
Homo sapiens phosphodiesterase 4A, cAMP-specific Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic Get druggable targets OG5_133100 All targets in OG5_133100
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase, isoform F, putative Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum IPR002073,3'5'-cyclic nucleotide phosphodiesterase,domain-containing Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4C, putative Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Cryptosporidium parvum membrane associated HD superfamily cyclic nucleotide phosphodiesterase domain containing protein Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative Get druggable targets OG5_128242 All targets in OG5_128242
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative Get druggable targets OG5_128242 All targets in OG5_128242
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase Get druggable targets OG5_128242 All targets in OG5_128242
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic Get druggable targets OG5_133100 All targets in OG5_133100
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_128242 All targets in OG5_128242
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A Get druggable targets OG5_128242 All targets in OG5_128242
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128242 All targets in OG5_128242
Neospora caninum cAMP-specific phosphodiesterase, putative Get druggable targets OG5_128242 All targets in OG5_128242
Schistosoma japonicum cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative Get druggable targets OG5_128242 All targets in OG5_128242
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0328 0.0495
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0098 0.028 0.028
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0277 0.092
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0103 0.2004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0104 0.1166
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0057 0.0087
Loa Loa (eye worm) endoplasmin 0.0033 0.0057 0.0087
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0042 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0097
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0076 0.0205 0.0205
Echinococcus granulosus phd:f box containing protein 0.0017 0.0004 0.0004
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0027 0.0037 0.0111
Entamoeba histolytica hypothetical protein 0.0024 0.0026 0.0039
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0089 0.025 0.025
Trypanosoma brucei Sphingosine kinase 0.0076 0.0205 0.0669
Leishmania major cAMP-specific phosphodiesterase, putative 0.0027 0.0037 0.0124
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0042 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0205 0.0681
Leishmania major diacylglycerol kinase-like protein 0.0076 0.0205 0.0681
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0253 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0157 0.1185
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0065 0.0063
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0328 0.0328
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.015 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Echinococcus multilocularis dnaJ subfamily B 0.294 1 1
Entamoeba histolytica hypothetical protein 0.0026 0.0034 0.0051
Schistosoma mansoni ran 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0042 0.0029
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0034 0.0385
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0085 0.0085
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.012 0.012
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0271 0.2047
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0895 0.3006 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0057 0.0086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0179 0.0237
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0027 0.0037 0.0037
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0018 0.0018
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0125 0.0373 0.0373
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0111 0.0369
Treponema pallidum phosphoglycerate kinase 0.0166 0.0512 1
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0037 0.0124
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0029 0.0042 0.0029
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.0277 0.0417
Echinococcus multilocularis heat shock protein 90 0.0033 0.0057 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0271 0.0271
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0034 0.0051
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0512 0.0512
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0076 0.0205 0.2287
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0157 0.1185
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0026 0.0287
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0045 0.0338
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0065 0.0063
Onchocerca volvulus 0.0018 0.0006 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0104 0.1166
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0027 0.0037 0.0124
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0042 0.0819
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0028 0.0093
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0153 0.0509
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0057 0.0441
Schistosoma mansoni hypothetical protein 0.0128 0.0381 0.0381
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0057 0.0428
Echinococcus granulosus dna polymerase kappa 0.0115 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0142 0.2424
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0027 0.0037 0.0111
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0038 0.0311
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0512 0.5724
Trypanosoma cruzi DNA polymerase kappa, putative 0.0115 0.0339 0.1128
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0058
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0027 0.0037 0.0729
Trypanosoma cruzi DNA polymerase eta, putative 0.0139 0.0421 0.14
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0111
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0253 0.0381
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0011 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0157 0.1185
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.3953
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0042 0.0029
Brugia malayi hypothetical protein 0.0033 0.0057 0.0428
Echinococcus granulosus snurportin 1 0.0313 0.1015 0.1015
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0001 0.0001
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0424 0.1393 0.4635
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0027 0.0037 0.0037
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0328 0.0462
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0153 0.0509
Brugia malayi hypothetical protein 0.0033 0.0057 0.0428
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0104 0.1166
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0729
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0076 0.0205 0.0205
Schistosoma mansoni hypothetical protein 0.0024 0.0026 0.0026
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0042 0.0469
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0142 0.0214
Schistosoma mansoni zinc finger protein 0.0035 0.0063 0.0063
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0065 0.0065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0104 0.1166
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0017 0.0017
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0037 0.0072 0.0109
Plasmodium falciparum acyl-CoA synthetase 0.0073 0.0193 0.376
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0048 0.0536
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Brugia malayi latrophilin 2 splice variant baaae 0.0276 0.0888 0.6703
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Loa Loa (eye worm) hypothetical protein 0.0033 0.0057 0.0086
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0104 0.1166
Giardia lamblia DNA damage repair protein 0.0028 0.0039 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0157 0.1185
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0097
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0004 0.0004
Brugia malayi jmjC domain containing protein 0.0017 0.0004 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0042 0.0317
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0126 0.0375 0.1247
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0157 0.1185
Plasmodium falciparum diacylglycerol kinase, putative 0.0076 0.0205 0.3995
Echinococcus granulosus endonuclease exonuclease phosphatase 0.022 0.0697 0.0697
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0179 0.0237
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0058 0.1123
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0004
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0042 0.0127
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0042 0.0317
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0065 0.0215
Trichomonas vaginalis endoplasmin, putative 0.002 0.0014 0.0154
Brugia malayi nuclear receptor RXR 0.0029 0.0045 0.0338
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0076 0.0205 0.0681
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0004 0.003
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0065 0.0063
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0028 0.0548
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0082 0.0124
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0042 0.0042
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0157 0.1185
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0097
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Brugia malayi polk-prov protein 0.0054 0.0128 0.0967
Loa Loa (eye worm) hypothetical protein 0.0076 0.0205 0.0309
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.0512 0.0773
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0065 0.0063
Mycobacterium tuberculosis Conserved protein 0.1954 0.6628 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0125 0.0373 0.0373
Brugia malayi SET domain containing protein 0.0018 0.0006 0.0049
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma cruzi DNA polymerase kappa, putative 0.0115 0.0339 0.1128
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Trypanosoma brucei unspecified product 0.0109 0.0317 0.1043
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0057 0.0191
Brugia malayi ecdysteroid receptor 0.0062 0.0157 0.1185
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0048 0.0536
Brugia malayi hypothetical protein 0.0076 0.0205 0.1545
Trypanosoma cruzi Sphingosine kinase 0.0076 0.0205 0.0681
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0328 0.3663
Echinococcus granulosus smad 0.0017 0.0004 0.0004
Plasmodium vivax DNA repair protein REV1, putative 0.0028 0.0039 0.0768
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0157 0.0157
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0328 0.0328
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0028 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0043 0.0093 0.014
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0042 0.0127
Schistosoma mansoni ran 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0128 0.0381 0.0381
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0103 0.0788
Entamoeba histolytica deoxycytidyl transferase, putative 0.0089 0.025 0.0378
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0128 0.0381 0.0381
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.0512 0.0512
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0016 0.0016
Schistosoma mansoni diacylglycerol kinase theta 0.0076 0.0205 0.0205
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0065 0.0065
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0125 0.0373 0.0562
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0023 0.0176
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0058 0.0442
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0001
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0007 0.0136
Schistosoma mansoni endoplasmin 0.0033 0.0057 0.0057
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0328 0.1091
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0065 0.0065
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0165 0.0536
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0157 0.0157
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0057 0.0191
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Chlamydia trachomatis phosphoglycerate kinase 0.0166 0.0512 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0193 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0034 0.0385
Trypanosoma cruzi diacylglycerol kinase, putative 0.0076 0.0205 0.0681
Brugia malayi beta-lactamase family protein 0.0035 0.0065 0.0487
Toxoplasma gondii ABC1 family protein 0.0035 0.0065 0.0496
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0223 0.0223
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0157 0.0157
Brugia malayi Eye-specific diacylglycerol kinase 0.0076 0.0205 0.1545
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0045 0.0045
Plasmodium falciparum phosphodiesterase gamma, putative 0.0027 0.0037 0.0729
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0058
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0103 0.1147
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0048 0.0603
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.022 0.0697 0.0697
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.015 0.015
Schistosoma mansoni heat shock protein 0.0033 0.0057 0.0057
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0328 0.0495
Echinococcus multilocularis endoplasmin 0.0026 0.0034 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0115 0.0339 0.1128
Mycobacterium ulcerans hypothetical protein 0.0471 0.1557 0.2322
Echinococcus multilocularis smad 0.0017 0.0004 0.0004
Trichomonas vaginalis ferritin, putative 0.0028 0.0039 0.0436
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0037 0.0111
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0157 0.0157
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0026 0.0086
Echinococcus granulosus intermediate filament protein 0.0026 0.0034 0.0034
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0045 0.0338
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0018 0.0355
Loa Loa (eye worm) hypothetical protein 0.0404 0.1325 0.2
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0276 0.0276
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0042 0.0029
Echinococcus multilocularis cpg binding protein 0.022 0.0697 0.0697
Brugia malayi diacylglycerol kinase 0.0076 0.0205 0.1545
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0328 0.0495
Brugia malayi ImpB/MucB/SamB family protein 0.0139 0.0421 0.3175
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0142 0.0471
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0024 0.0027 0.0041
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0027 0.0037 0.0124
Onchocerca volvulus 0.0206 0.065 0.8368
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0018 0.0061
Trichomonas vaginalis hypothetical protein 0.0025 0.003 0.0338
Entamoeba histolytica hypothetical protein, conserved 0.1954 0.6628 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0058 0.0058
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0214 0.0323
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0004 0.0004
Onchocerca volvulus 0.0026 0.0034 0.0437
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0049
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0076 0.0205 0.0205
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0042 0.039
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0142 0.1068
Loa Loa (eye worm) beta-lactamase 0.0035 0.0065 0.0097
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0512 0.0512
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.3953
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0045 0.0045
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0029 0.0042 0.039
Schistosoma mansoni cpg binding protein 0.022 0.0697 0.0697
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0104 0.1166
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0153 0.0509
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0142 0.2496
Loa Loa (eye worm) hypothetical protein 0.0276 0.0888 0.134
Schistosoma mansoni hypothetical protein 0.0128 0.0381 0.0381
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0072 0.0072
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0037 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0157 0.1185
Loa Loa (eye worm) hypothetical protein 0.008 0.0216 0.0326
Brugia malayi jmjC domain containing protein 0.0017 0.0004 0.0029
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0023 0.0446
Loa Loa (eye worm) ceramide kinase 0.0076 0.0205 0.0309
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0142 0.1581
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0042 0.0317
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0128 0.0381 0.0381
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0004 0.0006
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0064 0.0163 0.0163
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0157 0.0237
Mycobacterium ulcerans hypothetical protein 0.0035 0.0065 0.0063
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0027 0.0037 0.0056
Echinococcus multilocularis heat shock protein 0.0033 0.0057 0.0057
Brugia malayi jmjC domain containing protein 0.0079 0.0214 0.1616
Brugia malayi nuclear hormone receptor 0.0029 0.0045 0.0338
Echinococcus multilocularis protein dispatched 1 0.0047 0.0105 0.0105
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0057 0.0057
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0057 0.0642
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0156 0.052
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0042 0.014
Schistosoma mansoni bromodomain containing protein 0.002 0.0011 0.0011
Onchocerca volvulus 0.0033 0.0056 0.0715
Brugia malayi nuclear receptor NHR-67 0.0029 0.0045 0.0338
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0016 0.0175
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.015 0.015
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0024 0.0027 0.0536
Plasmodium vivax importin-beta 2, putative 0.0029 0.0045 0.0872
Brugia malayi phosphofructokinase 0.0112 0.0328 0.2474
Onchocerca volvulus Huntingtin homolog 0.0244 0.0777 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.006 0.015 0.0227
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0034 0.0115
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0512 0.1694
Loa Loa (eye worm) diacylglycerol kinase 2 0.0076 0.0205 0.0309
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0128 0.0381 0.0381
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0328 0.1079
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0039 0.0131
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Echinococcus multilocularis snurportin 1 0.0313 0.1015 0.1015
Trypanosoma brucei ISWI complex protein 0.0022 0.0019 0.0049
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0029 0.0042 0.0029
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0037 0.0282
Schistosoma mansoni hypothetical protein 0.004 0.008 0.008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0214 0.0214
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0028 0.0039 0.033
Onchocerca volvulus 0.0035 0.0065 0.0831
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0076 0.0205 0.0681
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0287
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0157 0.0157
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0328 0.1091
Loa Loa (eye worm) hypothetical protein 0.0053 0.0125 0.0189
Echinococcus granulosus heat shock protein 90 0.0026 0.0034 0.0034
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0028 0.0081
Mycobacterium tuberculosis Diacylglycerol kinase 0.0076 0.0205 0.0275
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0165 0.0249
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0096 0.0272 0.0906
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0048 0.0369
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0038 0.0744
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0076 0.0205 0.0205
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0097 0.0277 0.0384
Brugia malayi beta-lactamase family protein 0.0035 0.0065 0.0487
Onchocerca volvulus 0.0062 0.0157 0.2021
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0058 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0157 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0039 0.0131
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0034 0.0256
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Schistosoma mansoni cpg binding protein 0.022 0.0697 0.0697
Entamoeba histolytica diacylglycerol kinase, putative 0.0076 0.0205 0.0309
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0156 0.052
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0157 0.0157
Loa Loa (eye worm) glutaminase 0.0278 0.0895 0.1351
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0216 0.3953
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.006 0.006
Schistosoma mansoni ap endonuclease 0.0058 0.0142 0.0142
Mycobacterium leprae Probable lipase LipE 0.0035 0.0065 0.0852
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.0512 1
Trichomonas vaginalis sphingosine kinase, putative 0.0076 0.0205 0.2287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0157 0.0237
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Echinococcus multilocularis expressed protein 0.0028 0.0039 0.0039
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0037 0.0037
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0028 0.0039 0.0024
Toxoplasma gondii diacylglycerol kinase, putative 0.0076 0.0205 0.1572
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Schistosoma mansoni ferritin 0.0028 0.0039 0.0039
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0157 0.2021
Trichomonas vaginalis glutaminase, putative 0.0278 0.0895 1
Echinococcus granulosus ferritin 0.0028 0.0039 0.0039
Plasmodium vivax JmjC domain containing protein 0.0017 0.0004 0.0076
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0042 0.014
Echinococcus granulosus Diacylglycerol kinase theta 0.0076 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.005 0.0116 0.0175
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0042 0.0322
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0056
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0004 0.0006
Leishmania major hypothetical protein, conserved 0.0027 0.0037 0.0124
Mycobacterium ulcerans glutaminase 0.0278 0.0895 0.1321
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0125 0.0373 0.2861
Schistosoma mansoni apoferritin-2 0.0028 0.0039 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0065 0.126
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Trichomonas vaginalis helicase, putative 0.0047 0.0104 0.1166
Echinococcus multilocularis lamin dm0 0.0026 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0076 0.0205 0.0309
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0073 0.0193 0.3468
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0096 0.0272 0.0378
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0057 0.0441
Brugia malayi Diacylglycerol kinase protein 2 0.0076 0.0205 0.1545
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0168 0.0168
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0142 0.0459
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.3953
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0157 0.0157
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0048 0.0536
Brugia malayi Phosphoglycerate kinase 0.0061 0.0153 0.1154
Echinococcus multilocularis sphingosine kinase 1 0.1954 0.6628 0.6628
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0045 0.0045
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0126 0.0375 0.1247
Loa Loa (eye worm) hypothetical protein 0.0096 0.0271 0.0409
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0123 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0027 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0068 0.0177 0.0578
Echinococcus granulosus geminin 0.0355 0.1158 0.1158
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0048 0.0937
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.0512 0.0741
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0328 0.3663
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0013 0.002
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0045 0.0045
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0157 0.0157
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0063
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0028 0.0548
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.003
Echinococcus granulosus neuropeptide s receptor 0.0947 0.3184 0.3184
Brugia malayi ImpB/MucB/SamB family protein 0.0089 0.025 0.1889
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0042 0.014
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0001
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0045 0.0045
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0024 0.0027 0.0211
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.004
Entamoeba histolytica hypothetical protein 0.0077 0.0208 0.0313
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0045 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0048 0.0536
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0065 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Brugia malayi RNA, U transporter 1 0.0083 0.023 0.1732
Echinococcus multilocularis dna polymerase kappa 0.0115 0.0339 0.0339
Schistosoma mansoni nuclear receptor 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0028 0.0039 0.033
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0153 0.0496
Brugia malayi CXXC zinc finger family protein 0.0206 0.065 0.4907
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0065 0.0097
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0253 0.0253
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0057 0.0057
Onchocerca volvulus 0.0029 0.0045 0.0576
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0037 0.0282
Schistosoma mansoni bromodomain containing protein 0.0077 0.0208 0.0208
Entamoeba histolytica hypothetical protein 0.0077 0.0208 0.0313
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0023 0.0176
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0042 0.0029
Trypanosoma cruzi DNA polymerase eta, putative 0.0078 0.021 0.0698
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0038 0.0311
Schistosoma mansoni cpg binding protein 0.0206 0.065 0.065
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0464 0.0464
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.015 0.015
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0085 0.0085
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0412 0.0412
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.0512 1
Schistosoma mansoni hypothetical protein 0.0313 0.1015 0.1015
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0111
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.0277 0.0417
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0895 0.3006 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0125 0.0373 0.7172
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0157 0.0157
Echinococcus multilocularis neuropeptide s receptor 0.0947 0.3184 0.3184
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0142 0.018
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0027 0.0037 0.0124
Loa Loa (eye worm) hypothetical protein 0.0033 0.0057 0.0086
Loa Loa (eye worm) hypothetical protein 0.0139 0.0421 0.0635
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Plasmodium vivax diacylglycerol kinase, putative 0.0076 0.0205 0.3995
Mycobacterium tuberculosis Conserved protein 0.0035 0.0065 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0027 0.0037 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0037 0.0417
Loa Loa (eye worm) hypothetical protein 0.0244 0.0777 0.1173
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.0512 0.3934
Schistosoma mansoni glutaminase 0.0278 0.0895 0.0895
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0048 0.0536
Trypanosoma cruzi diacylglycerol kinase, putative 0.0076 0.0205 0.0681
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.1015 0.1531
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0058 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0157 0.1185
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0168 0.0168
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0157 0.0157
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0424 0.1393 0.4635
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0019 0.0207
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0057 0.0794
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0441 0.0441
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0085 0.0128
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Loa Loa (eye worm) hypothetical protein 0.0041 0.0085 0.0128
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0042 0.0469
Plasmodium falciparum DNA repair protein REV1, putative 0.0028 0.0039 0.0768
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0042 0.0322
Onchocerca volvulus 0.0029 0.0045 0.0576
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0018 0.0355
Echinococcus granulosus bloom syndrome protein 0.0021 0.0016 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0065 0.0065
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0045 0.0338
Trichomonas vaginalis esterase, putative 0.0035 0.0065 0.0721
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0037 0.0037
Mycobacterium ulcerans DNA polymerase IV 0.0115 0.0339 0.0479
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0157 0.0157
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0082 0.1296
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0042 0.0029
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0046 0.0046
Leishmania major DNA polymerase eta, putative 0.0139 0.0421 0.14
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0023 0.0446
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0157 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0019 0.0207
Echinococcus granulosus dna polymerase eta 0.0139 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0097
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0253 0.0253
Echinococcus multilocularis Smad4 0.0017 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0073 0.0193 0.0291
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.1954 0.6628 1
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0004
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0034 0.0328
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0142 0.0142
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0404 0.1325 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0142 0.2424
Trichomonas vaginalis diacylglycerol kinase, putative 0.0076 0.0205 0.2287
Brugia malayi jmjC domain containing protein 0.0017 0.0004 0.0029
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0157 0.0157
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0277 0.092
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0157 0.2021
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0512 0.5724
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0165 0.0548
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0024 0.0027 0.0307
Onchocerca volvulus 0.0035 0.0065 0.0831
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0045 0.0338
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0065 0.0063
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0057 0.0087
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0034 0.0115
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0205 0.2287
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0045 0.0045
Giardia lamblia DINP protein human, muc B family 0.0096 0.0272 0.5143
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0029 0.0042 0.0029
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0042 0.0819
Mycobacterium ulcerans hypothetical protein 0.0097 0.0277 0.0384
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0037 0.0124
Entamoeba histolytica diacylglycerol kinase, putative 0.0076 0.0205 0.0309
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0328 0.3663
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0123 0.0123
Trichomonas vaginalis DNA polymerase eta, putative 0.0115 0.0339 0.3788
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0048 0.0937
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Schistosoma mansoni patched 1 0.0041 0.0085 0.0085
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0042 0.0322
Brugia malayi Probable ClpP-like protease 0.008 0.0216 0.1633
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0001 0.0001
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0039 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0128 0.0414
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0128 0.0381 0.2877
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0065 0.0721
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0065 0.0063
Loa Loa (eye worm) hypothetical protein 0.0069 0.018 0.0272
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0018 0.0061
Echinococcus multilocularis expressed conserved protein 0.009 0.0251 0.0251
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0037 0.0124
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Schistosoma mansoni hypothetical protein 0.0355 0.1158 0.1158
Brugia malayi hypothetical protein 0.0029 0.0045 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0085 0.0946
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0128 0.0414
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0196 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0157 0.1185
Loa Loa (eye worm) latrophilin receptor protein 2 0.0128 0.0381 0.0575
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0157 0.0157
Loa Loa (eye worm) PDE1B protein 0.0027 0.0037 0.0056
Schistosoma mansoni sphingoid long chain base kinase 0.1954 0.6628 0.6628
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0029 0.0042 0.0029
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Schistosoma mansoni hypothetical protein 0.004 0.008 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0037 0.0124
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0156 0.052
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0045 0.0576
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0065 0.0721
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0024 0.0027 0.0187
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Leishmania major hypothetical protein, conserved 0.0076 0.0205 0.0681
Schistosoma mansoni hypothetical protein 0.004 0.008 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0277 0.0384
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0125 0.0125
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0072 0.0072
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0157 0.0157
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0057 0.0087
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Echinococcus granulosus ceramide kinase 0.0076 0.0205 0.0205
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0027 0.0037 0.0124
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0328 0.0328
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0037 0.0124
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0157 0.1185
Giardia lamblia Grp94/Hsp90 0.0026 0.0034 0.0328
Loa Loa (eye worm) hypothetical protein 0.0057 0.014 0.021
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0004 0.0004
Plasmodium vivax phosphodiesterase gamma, putative 0.0027 0.0037 0.0729
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Entamoeba histolytica Ran family GTPase 0.0022 0.0018 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0097
Onchocerca volvulus 0.0029 0.0042 0.054
Plasmodium vivax acyl-CoA synthetase, putative 0.0073 0.0193 0.376
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0051 0.0051
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.006 0.006
Mycobacterium tuberculosis Conserved protein 0.0035 0.0065 0.0063
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0039 0.0118
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0042 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0142 0.2763
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0042 0.014
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.4223
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0027 0.0037 0.0729
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0018 0.014
Echinococcus granulosus cpg binding protein 0.022 0.0697 0.0697
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0157 0.0157
Schistosoma mansoni heat shock protein 0.0033 0.0057 0.0057
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0512 0.1705
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0042 0.0029
Loa Loa (eye worm) oxidoreductase 0.0029 0.0042 0.0063
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0078 0.021 0.1611
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0464 0.3498
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0004 0.0004
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0165 0.1243
Brugia malayi Importin beta-1 subunit 0.0029 0.0045 0.0337
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0042 0.0029
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Brugia malayi nuclear receptor NHR-88 0.0062 0.0157 0.1185
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0097 0.0277 0.0384
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0157 0.0237
Trypanosoma brucei DNA polymerase eta, putative 0.0139 0.0421 0.1389
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0004 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0208 0.0208
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0125 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0045
Brugia malayi PHD-finger family protein 0.004 0.008 0.0606
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0057 0.0191
Leishmania major cathepsin L-like protease 0.0062 0.0156 0.052
Entamoeba histolytica diacylglycerol kinase, putative 0.0076 0.0205 0.0309
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0018 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0157 0.0237
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0004 0.0013
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Schistosoma mansoni diacylglycerol kinase theta 0.0076 0.0205 0.0205
Brugia malayi 6-phosphofructokinase 0.0112 0.0328 0.2474
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0027 0.0037 0.0037
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0024 0.0027 0.0027
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0712 0.1043
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0042 0.014
Trichomonas vaginalis dullard protein, putative 0.0024 0.0027 0.0307
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0165 0.0165
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0028 0.0216
Schistosoma mansoni hypothetical protein 0.0077 0.0208 0.0208
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0216 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0065 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0328 0.0495
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Onchocerca volvulus 0.0029 0.0042 0.054
Mycobacterium ulcerans diacylglycerol kinase 0.0076 0.0205 0.0275
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0051
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0027 0.0037 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0157 0.1185
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0058 0.0053
Brugia malayi intermediate filament protein 0.0026 0.0034 0.0256
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0042 0.0042
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0153 0.0509
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0328 0.0462
Schistosoma mansoni myst-related protein 0.0026 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0041
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0058 0.1123
Brugia malayi diacylglycerol kinase 0.0076 0.0205 0.1545
Brugia malayi Ceramide kinase 0.0076 0.0205 0.1545
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0142 0.0471
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1648 0.5581 0.5581
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0328 0.623
Leishmania major importin beta-1 subunit, putative 0.0024 0.0026 0.0086
Schistosoma mansoni ferritin light chain 0.0028 0.0039 0.0039
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0165 0.0165
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0076 0.0205 0.0205
Echinococcus multilocularis neuropeptide receptor A26 0.0947 0.3184 0.3184
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0064 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0157 0.1185
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Brugia malayi tailless protein 0.0029 0.0045 0.0338
Echinococcus granulosus sphingosine kinase 1 0.1954 0.6628 0.6628
Schistosoma mansoni lamin 0.0026 0.0034 0.0034
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0076 0.0205 0.1572
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0328 0.0495
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0076 0.0205 0.0309
Echinococcus granulosus GPCR family 2 0.0128 0.0381 0.0381
Entamoeba histolytica hypothetical protein 0.0077 0.0208 0.0313
Loa Loa (eye worm) hypothetical protein 0.0097 0.0277 0.0417
Brugia malayi glutaminase DH11.1 0.0278 0.0895 0.6754
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0019 0.0207
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0045 0.0136
Loa Loa (eye worm) acetyltransferase 0.0152 0.0464 0.0699
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0165 0.0548
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0057 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0017 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0045
Trypanosoma brucei diacylglycerol kinase, putative 0.0076 0.0205 0.0669
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0042 0.0042
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0034 0.0051
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0064 0.0064
Schistosoma mansoni DNA polymerase eta 0.0139 0.0421 0.0421
Leishmania major DNA damage repair protein, putative 0.0028 0.0039 0.0131
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0023 0.0063
Onchocerca volvulus 0.0035 0.0065 0.0831
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0024 0.0027 0.0078
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0128 0.0381 0.0575
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.0277 0.5184
Trypanosoma brucei chrX additional, unordered contigs 0.0028 0.0039 0.0118
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0016 0.0175
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0039 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0157 0.0237
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0097
Giardia lamblia Hypothetical protein 0.0027 0.0037 0.0387
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0048 0.0536
Echinococcus granulosus expressed conserved protein 0.009 0.0251 0.0251
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0034 0.0061 0.0471
Brugia malayi hypothetical protein 0.0024 0.0028 0.0212
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0034 0.0236
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0027 0.0037 0.0037
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0057 0.0178
Brugia malayi nuclear receptor NHR-88 0.0029 0.0045 0.0338
Loa Loa (eye worm) hypothetical protein 0.0166 0.0512 0.0773
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0004 0.0004
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0165 0.0165
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0027 0.0037 0.0037
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0004 0.0004
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.3953
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0048 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.003 0.0338
Brugia malayi heat shock protein 90 0.0033 0.0057 0.0433
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0001 0.0001
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0512 0.1705
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0223 0.0223
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0042 0.0063
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0004 0.0004
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0004 0.0004
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0157 0.0157
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0153 0.0509
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0196 0.0196
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0042 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0065 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0037 0.0124
Loa Loa (eye worm) histone methyltransferase 0.0064 0.0163 0.0246
Schistosoma mansoni zinc finger protein 0.0029 0.0045 0.0045
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0138 0.0459
Schistosoma mansoni Smad4 0.0017 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0062 0.0156 0.052
Echinococcus multilocularis geminin 0.0355 0.1158 0.1158
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0034 0.0017
Echinococcus granulosus Diacylglycerol kinase zeta 0.0076 0.0205 0.0205
Schistosoma mansoni ferritin 0.0028 0.0039 0.0039
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.0512 0.0512
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0208 0.0208
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0097 0.0277 0.0384
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0065 0.0063
Schistosoma mansoni SET domain protein 0.0018 0.0006 0.0006
Echinococcus granulosus heat shock protein 90 0.0033 0.0057 0.0057
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0034 0.0034
Trichomonas vaginalis diacylglycerol kinase, putative 0.0076 0.0205 0.2287
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Onchocerca volvulus 0.0029 0.0042 0.054
Brugia malayi hypothetical protein 0.0244 0.0777 0.5864
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0027 0.0037 0.0111
Echinococcus granulosus zinc finger protein 0.0035 0.0063 0.0063
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0065 0.0721
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Loa Loa (eye worm) hypothetical protein 0.0033 0.0057 0.0086
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0125 0.1613
Trichomonas vaginalis ran, putative 0.0022 0.0018 0.0203
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0004 0.0006
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0157 0.1185
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0058 0.0179
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0482 0.1592 0.1592
Brugia malayi Smad1 0.0017 0.0004 0.003
Echinococcus multilocularis heat shock protein 90 0.0026 0.0034 0.0034
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.0512 0.1705
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0272 0.0894
Giardia lamblia hypothetical protein 0.0027 0.0037 0.0387
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0034 0.0236
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0076 0.0205 0.2287
Schistosoma mansoni endoplasmin 0.0033 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0054 0.0128 0.0193
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0024 0.0027 0.0027
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0157 0.0157
Echinococcus granulosus mixed lineage leukemia protein mll 0.0051 0.012 0.012
Brugia malayi Latrophilin receptor protein 2 0.0128 0.0381 0.2877
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Brugia malayi hypothetical protein 0.0029 0.0045 0.0338
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0103 0.0103
Echinococcus multilocularis protein patched 0.0041 0.0085 0.0085
Entamoeba histolytica diacylglycerol kinase, putative 0.0076 0.0205 0.0309
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Brugia malayi mbt repeat family protein 0.0053 0.0125 0.0946
Treponema pallidum bacterioferrin (TpF1) 0.0028 0.0039 0.033
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0216 0.1661
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0277 0.2087
Loa Loa (eye worm) hypothetical protein 0.0082 0.0223 0.0337
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Loa Loa (eye worm) hypothetical protein 0.0097 0.0277 0.0417
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0056
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0165 0.0249
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0058 0.0192
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0253 0.0253
Brugia malayi ecdysone receptor 0.0029 0.0045 0.0338
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Brugia malayi Calcitonin receptor-like protein seb-1 0.0404 0.1325 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0058
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.0277 0.5184
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0216 0.0216
Brugia malayi jmjC domain containing protein 0.0017 0.0004 0.0029
Brugia malayi mbt repeat family protein 0.0053 0.0125 0.0946
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0157 0.0237
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0153 0.0509
Trypanosoma brucei DNA polymerase IV, putative 0.0115 0.0339 0.1117
Leishmania major hypothetical protein, conserved 0.0024 0.0028 0.0093
Brugia malayi F/Y-rich N-terminus family protein 0.0065 0.0166 0.1256
Trypanosoma brucei unspecified product 0.0062 0.0155 0.0505
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0082 0.1605
Mycobacterium ulcerans DNA polymerase IV 0.0115 0.0339 0.0479
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0287
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0045 0.0045
Treponema pallidum heat shock protein 90 0.0026 0.0034 0.0236
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0004 0.0076
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0404 0.1325 0.2
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0277 0.0384
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0125 0.0189
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0048 0.0072
Brugia malayi hypothetical protein 0.0077 0.0208 0.1567
Giardia lamblia Phosphoglycerate kinase 0.0166 0.0512 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0037 0.0124
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0142 0.018
Echinococcus granulosus endoplasmin 0.0026 0.0034 0.0034
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0057 0.0191
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0104 0.1166
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0157 0.0157
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0042
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0065 0.0721
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0038 0.0744
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0051 0.012 0.012
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0097 0.0277 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0729
Leishmania major mitochondrial DNA polymerase beta 0.0895 0.3006 1
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.0512 0.3934
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0039 0.0118
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0123 0.2039
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0277 0.2087
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0125 0.0373 0.0373
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0034 0.0385
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0034 0.0115
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0271 0.0409
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0153 0.0496
Mycobacterium tuberculosis Conserved hypothetical protein 0.0471 0.1557 0.2322
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0065 0.0721
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0027 0.0037 0.0282
Trypanosoma brucei DNA polymerase IV, putative 0.0115 0.0339 0.1117
Schistosoma mansoni hypothetical protein 0.0276 0.0888 0.0888
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0004 0.0004
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0058 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0097 0.0277 0.0384
Brugia malayi Bromodomain containing protein 0.0041 0.0085 0.0639
Loa Loa (eye worm) MH2 domain-containing protein 0.0256 0.0818 0.1235
Leishmania major hypothetical protein, conserved 0.0024 0.0027 0.0091
Echinococcus multilocularis GPCR, family 2 0.0128 0.0381 0.0381
Schistosoma mansoni coup transcription factor 0.0062 0.0157 0.0157
Brugia malayi beta-lactamase 0.0035 0.0065 0.0487
Loa Loa (eye worm) transcription factor SMAD2 0.0256 0.0818 0.1235
Trichomonas vaginalis dullard protein, putative 0.0024 0.0027 0.0307
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0089 0.025 0.0378
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0004 0.003
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0039 0.0131
Loa Loa (eye worm) hypothetical protein 0.0076 0.0205 0.0309
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0042 0.0317
Schistosoma mansoni microtubule-associated protein tau 0.2104 0.7141 0.7141
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0085 0.0085
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0029 0.0042 0.0029
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0068 0.0177 0.0578
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0157 0.0237
Toxoplasma gondii histone lysine methyltransferase SET1 0.0397 0.1302 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0048 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Loa Loa (eye worm) DR-78 0.0029 0.0045 0.0067
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0123 0.0151
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0125 0.0373 0.0373
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0097 0.0277 0.0384
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0051 0.0051
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.0512 1
Brugia malayi steroid hormone receptor 0.0062 0.0157 0.1185
Loa Loa (eye worm) Smad1 0.0017 0.0004 0.0006
Loa Loa (eye worm) glutaminase 2 0.0278 0.0895 0.1351
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0042 0.014
Toxoplasma gondii hypothetical protein 0.0027 0.0038 0.0293
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0089 0.025 0.025
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Schistosoma mansoni smad 0.0017 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0057 0.0086
Echinococcus multilocularis zinc finger protein 0.0035 0.0063 0.0063
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.015 0.1135
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0057 0.0178
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0042 0.0029
Schistosoma mansoni sphingosine kinase A B 0.1954 0.6628 0.6628
Entamoeba histolytica hypothetical protein 0.0077 0.0208 0.0313
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0073 0.0193 0.0257
Trichomonas vaginalis bmru protein, putative 0.0076 0.0205 0.2287
Echinococcus granulosus lamin 0.0026 0.0034 0.0034
Leishmania major DNA polymerase kappa, putative 0.0028 0.0039 0.0131
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0065 0.0487
Echinococcus multilocularis ceramide kinase 0.0076 0.0205 0.0205
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0065 0.0852
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0277 0.092
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.012 0.012
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0016 0.0118
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.0469 0.156
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0004 0.0004
Mycobacterium ulcerans acetyl-CoA synthetase 0.0029 0.0042 0.0029
Mycobacterium ulcerans hypothetical protein 0.1954 0.6628 1
Brugia malayi CHE-14 protein 0.0041 0.0085 0.0639
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0024 0.0027 0.0027
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0125 0.0373 0.0373
Trypanosoma brucei DNA polymerase kappa, putative 0.0068 0.0177 0.0578
Trichomonas vaginalis dullard protein, putative 0.0024 0.0027 0.0307
Onchocerca volvulus 0.0026 0.0034 0.0437
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0027 0.0037 0.0111
Schistosoma mansoni hypothetical protein 0.004 0.008 0.008
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0028 0.0548
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0024 0.0027 0.0307
Plasmodium falciparum importin beta, putative 0.0029 0.0045 0.0872
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0037 0.0124
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0126 0.0375 0.1247
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0023 0.0023 0.0035
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0157 0.0157
Brugia malayi Endoplasmin precursor 0.0033 0.0057 0.0433
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0157 0.0237
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0048 0.0369
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0512 0.1694
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0048 0.0937
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0045 0.0067
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0048 0.0513
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0018 0.0137
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0089 0.025 0.025
Mycobacterium ulcerans bacterioferritin BfrA 0.0028 0.0039 0.0024
Schistosoma mansoni hypothetical protein 0.0355 0.1158 0.1158
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0125 0.0125
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0024 0.0027 0.0207
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0058 0.0179
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Loa Loa (eye worm) hypothetical protein 0.0062 0.0157 0.0237
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0048 0.0536
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0018 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0157 0.1185
Mycobacterium ulcerans lipase LipD 0.0035 0.0065 0.0063
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0424 0.1393 0.4628
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0142 0.0471
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0004 0.0004
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0004 0.0013
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0034 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0027 0.0037 0.0037
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0045 0.0067
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0098 0.028 0.211
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0216 0.0216
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0216 0.1661
Trypanosoma cruzi ISWI complex protein 0.0022 0.0019 0.0062
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0058
Leishmania major hypothetical protein, conserved 0.0017 0.0004 0.0013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0157 0.0157
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0157 0.0157
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0024 0.0027 0.0536
Trypanosoma brucei unspecified product 0.0062 0.0155 0.0505
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0142 0.2763
Schistosoma mansoni ferritin 0.0028 0.0039 0.0039
Echinococcus granulosus heat shock protein 0.0033 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0333 0.1084 0.1084
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0328 0.623
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0125 0.0125
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0027 0.0037 0.0037
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0412 0.0412
Echinococcus granulosus CTD small phosphatase protein like 0.0024 0.0027 0.0027
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0042 0.0029
Trichomonas vaginalis sphingosine kinase, putative 0.0076 0.0205 0.2287
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0179 0.0237
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0223 0.0223
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0057 0.0191
Brugia malayi nuclear hormone receptor 0.0062 0.0157 0.1185
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.0512 1
Toxoplasma gondii hypothetical protein 0.0144 0.0438 0.3364
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0042 0.0317
Trichomonas vaginalis bmru protein, putative 0.0076 0.0205 0.2287
Echinococcus multilocularis ferritin 0.0028 0.0039 0.0039
Entamoeba histolytica acyl-coA synthetase, putative 0.0097 0.0277 0.0417
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0076 0.0205 0.0681
Mycobacterium ulcerans bacterioferritin BfrB 0.0028 0.0039 0.0024
Echinococcus granulosus microtubule associated protein 2 0.2104 0.7141 0.7141
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0193 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.0512 0.1705
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0104 0.1166
Brugia malayi MH2 domain containing protein 0.0256 0.0818 0.6174
Brugia malayi Phosphoglycerate kinase 0.0166 0.0512 0.3866
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0045 0.0338
Brugia malayi conserved hypotetical protein 0.0029 0.0045 0.0338
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0024 0.0027 0.0027
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0328 0.0495
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0028 0.0039 0.0302
Leishmania major hypothetical protein, conserved 0.0076 0.0205 0.0681
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0216 0.0293
Brugia malayi Bromodomain containing protein 0.0089 0.0247 0.1867
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0277 0.0384
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0128 0.0381 0.0381
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0076 0.0205 0.1572
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.0168 0.0168
Schistosoma mansoni ap endonuclease 0.0058 0.0142 0.0142
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0729
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Onchocerca volvulus Huntingtin homolog 0.0244 0.0777 1
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0125 0.0125
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0057 0.0178
Schistosoma mansoni hypothetical protein 0.0076 0.0205 0.0205
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0165 0.0548
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0057 0.1121
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.0512 0.0741
Schistosoma mansoni DNA polymerase IV / kappa 0.0028 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0073 0.0193 0.0291
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0205 0.0669
Schistosoma mansoni lamin 0.0026 0.0034 0.0034
Leishmania major DNA polymerase kappa, putative 0.0096 0.0272 0.0906
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0223 0.1686
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0021 0.0017 0.0017
Echinococcus granulosus Smad4 0.0017 0.0004 0.0004
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.003
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.003
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0029 0.0042 0.0029
Schistosoma mansoni intermediate filament proteins 0.0026 0.0034 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0057 0.0057
Plasmodium falciparum heat shock protein 90 0.0033 0.0057 0.1121
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0464 0.0464
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0438 0.1442 0.1442
Schistosoma mansoni apoferritin-2 0.0028 0.0039 0.0039
Plasmodium falciparum phosphodiesterase delta, putative 0.0027 0.0037 0.0729
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0048 0.0513
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0045 0.0045
Echinococcus granulosus lamin dm0 0.0026 0.0034 0.0034
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0027 0.0037 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0179 0.0237
Trichomonas vaginalis heat shock protein, putative 0.002 0.0014 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Mycobacterium ulcerans hypothetical protein 0.0028 0.0039 0.0025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0142 0.0214
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.015 0.015
Mycobacterium tuberculosis Conserved protein 0.0035 0.0065 0.0063
Brugia malayi nuclear receptor RXR 0.0033 0.0057 0.0428
Onchocerca volvulus Ceramide kinase 1 homolog 0.0076 0.0205 0.2634
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0271 0.0271
Schistosoma mansoni hypothetical protein 0.002 0.0013 0.0013
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0027 0.0037 0.0037
Schistosoma mansoni nuclear receptor 0.0029 0.0045 0.0045
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0115 0.0339 0.3788
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0058 0.0442
Brugia malayi 6-phosphofructokinase 0.0112 0.0328 0.2474
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0056
Plasmodium vivax diacylglycerol kinase, putative 0.0076 0.0205 0.3995
Leishmania major GTP-binding protein, putative 0.0022 0.0018 0.0061
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0027 0.0037 0.0124
Trypanosoma brucei DNA polymerase IV, putative 0.0109 0.0317 0.1043
Onchocerca volvulus 0.0097 0.0277 0.3559
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0037 0.0417
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0023 0.0076
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0058 0.0087
Loa Loa (eye worm) RecQ helicase 0.0021 0.0016 0.0024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0103 0.1147
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0037 0.0282
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0004 0.0006
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0027 0.0037 0.0037
Mycobacterium tuberculosis Conserved hypothetical protein 0.0089 0.025 0.0344
Leishmania major DNA polymerase eta, putative 0.0078 0.021 0.0698
Plasmodium falciparum diacylglycerol kinase, putative 0.0076 0.0205 0.3995
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0024 0.0027 0.0536
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0253 0.1905
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0076 0.0205 0.2287
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0065 0.0063
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0157 0.0157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0253 0.0253
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Loa Loa (eye worm) hypothetical protein 0.0073 0.0193 0.0291
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0045 0.0338
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0156 0.052
Loa Loa (eye worm) CXXC zinc finger family protein 0.0206 0.065 0.0981
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0045 0.0576
Trypanosoma brucei heat shock protein, putative 0.0033 0.0057 0.0178
Echinococcus granulosus histone lysine methyltransferase setb 0.0021 0.0017 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0028 0.0093
Plasmodium vivax endoplasmin, putative 0.0033 0.0057 0.1121
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0018 0.0048
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0037 0.0124
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0057 0.0428
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0045 0.0136
Brugia malayi isocitrate dehydrogenase 0.0033 0.0058 0.0434
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0037 0.0417
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0042 0.0029
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0048 0.0937
Schistosoma mansoni myst-related protein 0.0026 0.0034 0.0034
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0004
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0098 0.028 0.028
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0076 0.0205 0.0669
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0157 0.0157
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0123 0.0151
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Brugia malayi jmjC domain containing protein 0.0065 0.0168 0.1264
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0045 0.0067
Onchocerca volvulus 0.0053 0.0125 0.1613
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0037 0.0417
Loa Loa (eye worm) MBCTL1 0.006 0.015 0.0227
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Leishmania major hypothetical protein, conserved 0.0035 0.0065 0.0215
Echinococcus multilocularis Diacylglycerol kinase theta 0.0076 0.0205 0.0205
Echinococcus granulosus importin subunit beta 1 0.0029 0.0045 0.0045
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0098 0.028 0.0422
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0157 0.0157
Leishmania major heat shock protein 83-1 0.0033 0.0057 0.0191
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0328 0.0328
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.012 0.012
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0028 0.0008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0142 0.0142
Onchocerca volvulus 0.0076 0.0205 0.2634
Loa Loa (eye worm) hypothetical protein 0.0073 0.0193 0.0291
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0029 0.0042 0.039
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0024 0.0027 0.0307
Schistosoma mansoni importin beta-1 0.0029 0.0045 0.0045
Toxoplasma gondii exonuclease III APE 0.0058 0.0142 0.1087
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0157 0.1185
Trypanosoma cruzi Sphingosine kinase 0.0076 0.0205 0.0681
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0216 0.4223
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0042 0.0063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0338
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0045 0.0343
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0027 0.0037 0.0417
Echinococcus multilocularis musashi 0.0026 0.0034 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0328 0.3663
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0895 0.3006 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0104 0.1166
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0103 0.0788
Schistosoma mansoni ferritin 0.0028 0.0039 0.0039
Echinococcus multilocularis dna polymerase eta 0.0139 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0006
Plasmodium falciparum zinc finger protein, putative 0.0026 0.0034 0.0665
Mycobacterium ulcerans beta-lactamase 0.0035 0.0065 0.0063
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0253 0.0253
Echinococcus granulosus expressed protein 0.0028 0.0039 0.0039
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0156 0.0507
Echinococcus granulosus lysine specific demethylase 5A 0.0079 0.0214 0.0214
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0037 0.0124
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0039 0.0118
Leishmania major sphingosine kinase A, B, putative 0.0076 0.0205 0.0681
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0057 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0157 0.1185
Schistosoma mansoni hypothetical protein 0.294 1 1
Leishmania major diacylglycerol kinase, putative 0.0076 0.0205 0.0681
Loa Loa (eye worm) hypothetical protein 0.0097 0.0277 0.0417
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0058 0.0192
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0142 0.1581
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0065 0.0063
Schistosoma mansoni ferritin light chain 0.0028 0.0039 0.0039
Plasmodium falciparum endoplasmin, putative 0.002 0.0014 0.0268
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0157 0.2021
Echinococcus granulosus neuropeptide receptor A26 0.0947 0.3184 0.3184
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0027 0.0037 0.0417
Onchocerca volvulus 0.0082 0.0223 0.2874
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0157 0.0157
Echinococcus multilocularis lamin 0.0026 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0115 0.0339 0.1117
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0064 0.0163 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0277 0.2087
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0024 0.0027 0.0307
Trypanosoma cruzi DNA polymerase kappa, putative 0.0115 0.0339 0.1128
Schistosoma mansoni terminal deoxycytidyl transferase 0.0089 0.025 0.025
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0729
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0004 0.0004
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0125 0.0125
Leishmania major hypothetical protein, conserved 0.0027 0.0037 0.0124
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0037 0.0287
Echinococcus multilocularis microtubule associated protein 2 0.2104 0.7141 0.7141
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0042 0.0029
Loa Loa (eye worm) hypothetical protein 0.0244 0.0777 0.1173
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0208 0.0208
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0729
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0042 0.014
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0037 0.0417
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0126 0.0375 0.1236
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0157 0.0157
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0157 0.0157
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0027 0.0037 0.0037
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0029 0.0042 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0067
Leishmania major cathepsin L-like protease 0.0062 0.0156 0.052
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0004 0.0006
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0482 0.1592 0.1592
Schistosoma mansoni hypothetical protein 0.0128 0.0381 0.0381
Echinococcus multilocularis 0.0024 0.0027 0.0027

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 4.9 nM Inhibition of human full length PDE4A4 expressed in baculovirus infected sf21 cells ChEMBL. 23806553
IC50 (binding) > 5000 nM Inhibition of human full length PDE7A1 expressed in baculovirus infected sf21 cells ChEMBL. 23806553

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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