Detailed information for compound 2075626

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 459.486 | Formula: C19H24F3N5O3S
  • H donors: 1 H acceptors: 5 LogP: -0.37 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(F)(F)F.Cn1ncc(c1)N1CCC2(C1=O)CCCN(C2)Cc1csc(n1)C
  • InChi: 1S/C17H23N5OS.C2HF3O2/c1-13-19-14(11-24-13)9-21-6-3-4-17(12-21)5-7-22(16(17)23)15-8-18-20(2)10-15;3-2(4,5)1(6)7/h8,10-11H,3-7,9,12H2,1-2H3;(H,6,7)
  • InChiKey: DVVWOIIZXNOFBG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus peroxidasin 0.0587 0.5979 0.5953
Trichomonas vaginalis tubulin alpha chain, putative 0.0226 0.2168 0.3149
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0072 0.0537 0.0476
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Brugia malayi tubulin alpha-2 chain 0.0532 0.5397 0.8
Brugia malayi Pre-SET motif family protein 0.0034 0.0133 0.0171
Trypanosoma cruzi cytochrome P450, putative 0.0117 0.1011 0.125
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.028 0.0321
Onchocerca volvulus Peroxidase homolog 0.0587 0.5979 1
Echinococcus granulosus smad 0.0036 0.016 0.0097
Leishmania major beta tubulin 0.066 0.6742 1
Trypanosoma brucei alpha tubulin 0.0532 0.5397 0.8005
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Loa Loa (eye worm) hypothetical protein 0.0057 0.0383 0.0543
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0312 0.042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0237 0.0326
Trypanosoma brucei beta tubulin 0.066 0.6742 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0039 0.0193 0.1098
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.0237 0.0326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0312 0.0369
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0359 0.3563 0.5272
Loa Loa (eye worm) hypothetical protein 0.0085 0.0675 0.0978
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0989 0.1429
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Brugia malayi photoreceptor-specific nuclear receptor 0.0046 0.0262 0.0363
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0675 0.0616
Brugia malayi Cadherin domain containing protein 0.0076 0.0579 0.0835
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0262 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0203 0.0205
Loa Loa (eye worm) CYP4Cod1 0.0117 0.1011 0.1478
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0039 0.0193 0.1098
Giardia lamblia GTOR 0.0051 0.0312 0.0116
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0237 0.1375
Loa Loa (eye worm) hypothetical protein 0.0058 0.0393 0.0559
Onchocerca volvulus Chorion peroxidase homolog 0.0587 0.5979 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0046 0.0262 0.02
Trypanosoma brucei zeta tubulin, putative 0.0174 0.1612 0.2391
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Echinococcus multilocularis lamin 0.0119 0.1031 0.0973
Brugia malayi Delta serrate ligand family protein 0.0076 0.0579 0.0835
Leishmania major beta tubulin 0.066 0.6742 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0039 0.0193 0.1098
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0039 0.0193 0.1098
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0262 0.0363
Leishmania major beta tubulin 0.066 0.6742 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0072 0.0537 0.0476
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Plasmodium vivax delta tubulin, putative 0.0174 0.1612 0.2357
Echinococcus granulosus Tubulin alpha 1 chain 0.0532 0.5397 0.5367
Schistosoma mansoni hypothetical protein 0.0046 0.0262 0.02
Echinococcus multilocularis Smad4 0.0036 0.016 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0039 0.0193 0.1098
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0051 0.0321 0.0259
Echinococcus granulosus slit 2 protein 0.0076 0.0579 0.0519
Leishmania major beta tubulin 0.066 0.6742 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0046 0.0262 0.02
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.021
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0046 0.0262 0.02
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0086 0.0689 0.0981
Echinococcus granulosus neurogenic locus notch protein 0.0076 0.0579 0.0519
Echinococcus granulosus protein jagged 2 0.0076 0.0579 0.0519
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0039 0.0193 0.1098
Schistosoma mansoni peroxidasin 0.0587 0.5979 0.5953
Leishmania major zeta tubulin, putative 0.0174 0.1612 0.2357
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0989 0.1157
Schistosoma mansoni notch 0.0076 0.0579 0.0519
Trypanosoma cruzi cytochrome P450, putative 0.0117 0.1011 0.125
Loa Loa (eye worm) Notch2 0.0076 0.0579 0.0835
Loa Loa (eye worm) cytochrome P450 family protein 0.0117 0.1011 0.1478
Loa Loa (eye worm) isocitrate dehydrogenase 0.0072 0.0537 0.0772
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Echinococcus multilocularis neurogenic locus protein delta 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0043 0.0237 0.0326
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0072 0.0537 0.0476
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0262 0.02
Plasmodium vivax tubulin epsilon chain, putative 0.04 0.4002 0.5918
Toxoplasma gondii alpha tubulin TUBA1 0.0532 0.5397 0.7996
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0046 0.0262 0.0363
Trypanosoma brucei alpha tubulin 0.0532 0.5397 0.8005
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.0237 0.0174
Loa Loa (eye worm) hypothetical protein 0.0154 0.1409 0.2069
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0039 0.0193 0.1098
Giardia lamblia Alpha-tubulin 0.0532 0.5397 0.7932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0312 0.0369
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0039 0.0193 0.1098
Onchocerca volvulus Slit protein homolog 0.0076 0.0579 0.0942
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0237 0.0351
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0312 0.0182
Plasmodium falciparum ataxin-2 like protein, putative 0.0115 0.0989 0.1428
Onchocerca volvulus 0.0076 0.0579 0.0942
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0064 0.0068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0262 0.0363
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Leishmania major beta tubulin 0.066 0.6742 1
Brugia malayi Tubulin alpha-2 chain 0.0532 0.5397 0.8
Brugia malayi Tubulin alpha-2 chain 0.0532 0.5397 0.8
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0046 0.0262 0.02
Brugia malayi CHE-14 protein 0.0048 0.028 0.0391
Schistosoma mansoni hypothetical protein 0.0968 1 1
Schistosoma mansoni tubulin subunit beta 0.066 0.6742 0.6721
Echinococcus multilocularis tubulin alpha 1C chain 0.0532 0.5397 0.5367
Echinococcus granulosus notch 0.0076 0.0579 0.0519
Loa Loa (eye worm) MH1 domain-containing protein 0.0036 0.016 0.0211
Schistosoma mansoni thyroid hormone receptor 0.0046 0.0262 0.02
Brugia malayi isocitrate dehydrogenase 0.0072 0.0537 0.0772
Echinococcus multilocularis tubulin alpha chain 0.0532 0.5397 0.5367
Toxoplasma gondii beta tubulin 0.066 0.6742 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0046 0.0262 0.02
Loa Loa (eye worm) blistered cuticle protein 3 0.0587 0.5979 0.8865
Schistosoma mansoni tubulin subunit beta 0.066 0.6742 0.6721
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0322 0.026
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Leishmania major beta tubulin 0.066 0.6742 1
Onchocerca volvulus 0.0074 0.0562 0.0913
Echinococcus granulosus lamin 0.0119 0.1031 0.0973
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0046 0.0262 0.02
Brugia malayi Peroxidasin 0.0587 0.5979 0.8865
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0088
Echinococcus granulosus survival motor neuron protein 1 0.0266 0.2589 0.2541
Brugia malayi Cytochrome P450 family protein 0.0117 0.1011 0.1478
Trichomonas vaginalis tubulin beta chain, putative 0.0532 0.5397 0.7985
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0072 0.0537 0.0796
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0203 0.0258
Trichomonas vaginalis tubulin beta chain, putative 0.0532 0.5397 0.7985
Echinococcus granulosus cytochrome P450 2K1 0.0039 0.0193 0.013
Brugia malayi Tubulin gamma chain 0.04 0.4002 0.5926
Schistosoma mansoni tubulin subunit beta 0.066 0.6742 0.6721
Toxoplasma gondii endonuclease IV APN 0.0086 0.0689 0.0981
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0226 0.2168 0.3149
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0579 0.0835
Echinococcus multilocularis beta tubulin 0.066 0.6742 0.6721
Echinococcus multilocularis tubulin subunit TubB 0.0532 0.5397 0.5367
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0039 0.0193 0.1098
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0039 0.0193 0.1098
Loa Loa (eye worm) hypothetical protein 0.0184 0.1718 0.2529
Echinococcus multilocularis neurogenic locus protein delta 0.0076 0.0579 0.0519
Schistosoma mansoni jun-related protein 0.0077 0.0589 0.0529
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0068
Schistosoma mansoni retinoic acid receptor RXR 0.0046 0.0262 0.02
Trichomonas vaginalis tubulin beta chain, putative 0.0532 0.5397 0.7985
Mycobacterium ulcerans endonuclease IV 0.0086 0.0689 0.4211
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Echinococcus multilocularis neurogenic locus notch protein 0.0076 0.0579 0.0519
Giardia lamblia Alpha-tubulin 0.0532 0.5397 0.7932
Echinococcus multilocularis Tubulin beta 2C chain 0.066 0.6742 0.6721
Loa Loa (eye worm) MH2 domain-containing protein 0.0531 0.5381 0.7976
Loa Loa (eye worm) hypothetical protein 0.0115 0.0989 0.1444
Echinococcus granulosus tubulin alpha 1C chain 0.0532 0.5397 0.5367
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0039 0.0193 0.1098
Brugia malayi Isocitrate dehydrogenase 0.0072 0.0537 0.0772
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0174 0.1612 0.2357
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0989 0.1383
Trypanosoma cruzi epsilon tubulin, putative 0.04 0.4002 0.5817
Trichomonas vaginalis tubulin beta chain, putative 0.0532 0.5397 0.7985
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.003 0.0045
Loa Loa (eye worm) hypothetical protein 0.0056 0.0366 0.0518
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Echinococcus multilocularis Tubulin beta 2C chain 0.066 0.6742 0.6721
Echinococcus granulosus ecdysone induced protein 78C 0.0046 0.0262 0.02
Echinococcus granulosus tubulin gamma 1 chain 0.04 0.4002 0.3964
Echinococcus multilocularis isocitrate dehydrogenase 0.0072 0.0537 0.0476
Plasmodium vivax tubulin gamma chain, putative 0.04 0.4002 0.5918
Trichomonas vaginalis tubulin epsilon chain, putative 0.0174 0.1612 0.2316
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0039 0.0193 0.1098
Plasmodium falciparum tubulin delta chain, putative 0.0174 0.1612 0.2357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0136 0.0105
Loa Loa (eye worm) tubulin alpha-3 chain 0.0306 0.3007 0.4445
Echinococcus multilocularis peroxidasin 0.0587 0.5979 0.5953
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0158 0.1449 0.1394
Onchocerca volvulus 0.0056 0.0366 0.0584
Onchocerca volvulus 0.0076 0.0579 0.0942
Trypanosoma cruzi zeta tubulin, putative 0.0174 0.1612 0.2167
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Brugia malayi hypothetical protein 0.0027 0.0064 0.0068
Trypanosoma cruzi tubulin delta chain 0.0174 0.1612 0.2167
Trichomonas vaginalis tubulin, putative 0.0174 0.1612 0.2316
Onchocerca volvulus Peroxidasin homolog 0.0587 0.5979 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0237 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.1612 0.2316
Entamoeba histolytica tubulin family protein 0.066 0.6742 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0036 0.016 0.0097
Onchocerca volvulus 0.0587 0.5979 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0097 0.0047
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0237 0.0067
Schistosoma mansoni Smad4 0.0036 0.016 0.0097
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0039 0.0193 0.1098
Trichomonas vaginalis tubulin beta chain, putative 0.0532 0.5397 0.7985
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0086 0.0689 0.0981
Schistosoma mansoni smad 0.0036 0.016 0.0097
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0064 0.0458 0.2701
Brugia malayi hypothetical protein 0.0158 0.1449 0.2129
Brugia malayi Cadherin domain containing protein 0.0076 0.0579 0.0835
Echinococcus granulosus microtubule associated protein 2 0.0777 0.7981 0.7968
Leishmania major cytochrome p450-like protein 0.0039 0.0193 0.0242
Brugia malayi cytoplasmic intermediate filament protein 0.0064 0.0449 0.0642
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Loa Loa (eye worm) BEN-1 protein 0.066 0.6742 1
Echinococcus multilocularis tumor protein p63 0.0381 0.3794 0.3755
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.05 0.0699
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Onchocerca volvulus 0.0119 0.1031 0.1699
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.028 0.0218
Toxoplasma gondii cytochrome p450 superfamily protein 0.0039 0.0193 0.0242
Echinococcus multilocularis fat cadherin tumor suppressor 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0068
Onchocerca volvulus Neurogenic locus notch homolog 0.0076 0.0579 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.0001
Brugia malayi Pre-SET motif family protein 0.0234 0.2252 0.3323
Loa Loa (eye worm) tubulin beta-4 chain 0.066 0.6742 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.1008 0.1473
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0036 0.016 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0039 0.0193 0.1098
Echinococcus granulosus tubulin alpha chain 0.0532 0.5397 0.5367
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Trypanosoma brucei unspecified product 0.0043 0.0237 0.0351
Brugia malayi Muscle positioning protein 4 0.0076 0.0579 0.0835
Brugia malayi Animal haem peroxidase family protein 0.0587 0.5979 0.8865
Entamoeba histolytica tubulin alpha-1 chain 0.0532 0.5397 0.7996
Echinococcus multilocularis protein jagged 1 0.0076 0.0579 0.0519
Echinococcus multilocularis tubulin alpha chain 0.0532 0.5397 0.5367
Echinococcus multilocularis survival motor neuron protein 1 0.0266 0.2589 0.2541
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0989 0.1216
Echinococcus granulosus expressed conserved protein 0.0104 0.0877 0.0819
Leishmania major gamma-tubulin 0.04 0.4002 0.5918
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0046 0.0262 0.02
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Echinococcus granulosus Protein patched homolog 1 0.0048 0.028 0.0218
Brugia malayi MAP kinase sur-1 0.0115 0.0989 0.1445
Echinococcus multilocularis notch 0.0076 0.0579 0.0519
Schistosoma mansoni laminin gamma-3 chain 0.0076 0.0579 0.0519
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0111 0.0948 0.1368
Leishmania major cytochrome p450-like protein 0.0117 0.1011 0.1461
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0262 0.0363
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Brugia malayi MH1 domain containing protein 0.0036 0.016 0.0211
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Echinococcus multilocularis expressed conserved protein 0.0104 0.0877 0.0819
Brugia malayi Niemann-Pick C1 protein precursor 0.0111 0.0948 0.1384
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0039 0.0193 0.1098
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0068
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0064 0.0458 0.0679
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0046 0.0262 0.0363
Leishmania major beta tubulin 0.066 0.6742 1
Brugia malayi hypothetical protein 0.0154 0.1409 0.2069
Echinococcus granulosus beta tubulin 0.066 0.6742 0.6721
Onchocerca volvulus Putative cubilin 0.0076 0.0579 0.0942
Leishmania major cytochrome p450-like protein 0.0039 0.0193 0.0242
Echinococcus granulosus neurogenic locus notch protein 4 0.0076 0.0579 0.0519
Trypanosoma brucei protein kinase, putative 0.0115 0.0989 0.1468
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0094 0.0042
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0039 0.0193 0.1098
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0262 0.02
Loa Loa (eye worm) hypoxia-induced factor 1 0.017 0.1568 0.2305
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0262 0.02
Loa Loa (eye worm) hypothetical protein 0.0266 0.2589 0.3824
Loa Loa (eye worm) tubulin alpha chain 0.0532 0.5397 0.8
Leishmania major beta tubulin 0.066 0.6742 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0646 0.0935
Schistosoma mansoni alpha tubulin 0.0532 0.5397 0.5367
Trichomonas vaginalis tubulin, putative 0.0226 0.2168 0.3149
Leishmania major beta tubulin 0.066 0.6742 1
Brugia malayi alpha-tubulin 0.0532 0.5397 0.8
Schistosoma mansoni hypothetical protein 0.0037 0.0167 0.0104
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0312 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0322 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0095 0.014
Schistosoma mansoni notch 0.0076 0.0579 0.0519
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.05 0.0699
Trypanosoma brucei beta tubulin 0.066 0.6742 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0095 0.0776 0.0717
Trichomonas vaginalis tubulin beta chain, putative 0.0532 0.5397 0.7985
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0989 0.1468
Giardia lamblia Beta tubulin 0.066 0.6742 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0039 0.0193 0.1098
Echinococcus granulosus Tubulin alpha 1 chain 0.0532 0.5397 0.5367
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0095 0.0776 0.0717
Loa Loa (eye worm) hypothetical protein 0.0306 0.3007 0.4445
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0039 0.0193 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Brugia malayi hypothetical protein 0.0074 0.0562 0.0809
Schistosoma mansoni notch 0.0076 0.0579 0.0519
Toxoplasma gondii beta-1 tubulin, putative 0.066 0.6742 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0039 0.0193 0.1098
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Brugia malayi intermediate filament protein 0.0119 0.1031 0.1507
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0237 0.1375
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0039 0.0193 0.1098
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Schistosoma mansoni alpha tubulin 0.0532 0.5397 0.5367
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0203 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0046 0.0262 0.0363
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0237 0.1375
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Echinococcus multilocularis protein jagged 2 0.0076 0.0579 0.0519
Plasmodium falciparum tubulin epsilon chain, putative 0.04 0.4002 0.5918
Plasmodium falciparum alpha tubulin 1 0.0532 0.5397 0.7996
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0989 0.0932
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0076 0.0579 0.0835
Echinococcus granulosus Tubulin beta 2C chain 0.066 0.6742 0.6721
Leishmania major beta tubulin 0.066 0.6742 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0046 0.0262 0.02
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0046 0.0262 0.0363
Echinococcus granulosus peroxisome assembly protein 26 0.0532 0.5397 0.5367
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0237 0.0067
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.0237 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.028 0.0391
Echinococcus multilocularis protein jagged 1 0.0076 0.0579 0.0519
Entamoeba histolytica hypothetical protein 0.0158 0.1449 0.2114
Brugia malayi MH1 domain containing protein 0.0036 0.016 0.0211
Leishmania major DNA polymerase eta, putative 0.0043 0.0237 0.0308
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.003 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0064 0.0458 0.0404
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Mycobacterium tuberculosis Cell division protein FtsZ 0.0174 0.1612 1
Trichomonas vaginalis tubulin alpha chain, putative 0.066 0.6742 1
Leishmania major beta tubulin 0.066 0.6742 1
Brugia malayi hypothetical protein 0.0184 0.1718 0.2529
Echinococcus multilocularis GPCR, family 2 0.0037 0.0167 0.0104
Schistosoma mansoni smad1 5 8 and 0.0036 0.016 0.0097
Schistosoma mansoni hypothetical protein 0.0039 0.0193 0.013
Trypanosoma cruzi epsilon tubulin, putative 0.04 0.4002 0.5817
Trypanosoma cruzi PAB1-binding protein , putative 0.0115 0.0989 0.1215
Brugia malayi GCC2 and GCC3 family protein 0.0076 0.0579 0.0835
Giardia lamblia Beta tubulin 0.066 0.6742 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Echinococcus granulosus tubulin alpha 1C chain 0.0532 0.5397 0.5367
Leishmania major beta tubulin 0.066 0.6742 1
Echinococcus multilocularis Tubulin beta 2C chain 0.066 0.6742 0.6721
Onchocerca volvulus 0.0226 0.2168 0.3607
Echinococcus multilocularis tubulin epsilon chain 0.04 0.4002 0.3964
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0989 0.1383
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0174 0.1612 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Brugia malayi PAS domain containing protein 0.0055 0.0356 0.0504
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0237 0.0308
Schistosoma mansoni tubulin subunit epsilon 0.04 0.4002 0.3964
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0051 0.0321 0.0259
Onchocerca volvulus 0.0587 0.5979 1
Onchocerca volvulus 0.0076 0.0579 0.0942
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0068
Schistosoma mansoni coup transcription factor 0.0046 0.0262 0.02
Echinococcus multilocularis neuropeptide s receptor 0.0523 0.5294 0.5263
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0257 0.0194
Loa Loa (eye worm) transcription factor SMAD2 0.0531 0.5381 0.7976
Leishmania major beta tubulin 0.066 0.6742 1
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0133 0.007
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0133 0.007
Giardia lamblia Gamma tubulin 0.04 0.4002 0.5788
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0039 0.0193 0.1098
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.0237 0.0174
Mycobacterium leprae cell division protein FtsZ 0.0174 0.1612 1
Brugia malayi exodeoxyribonuclease III family protein 0.0064 0.0458 0.0654
Schistosoma mansoni survival motor neuron protein 0.0054 0.0351 0.029
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0167 0.0222
Loa Loa (eye worm) hypothetical protein 0.0037 0.0167 0.0222
Loa Loa (eye worm) notch protein 0.0076 0.0579 0.0835
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0359 0.3563 0.5238
Echinococcus multilocularis tubulin alpha chain 0.0532 0.5397 0.5367
Loa Loa (eye worm) tubulin gamma chain 0.04 0.4002 0.5926
Schistosoma mansoni hypothetical protein 0.0054 0.0351 0.029
Trypanosoma brucei beta tubulin 0.066 0.6742 1
Echinococcus granulosus neuropeptide s receptor 0.0523 0.5294 0.5263
Onchocerca volvulus 0.0076 0.0579 0.0942
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.04 0.4002 0.5918
Leishmania major delta tubulin, putative 0.0174 0.1612 0.2357
Schistosoma mansoni smad1 5 8 and 0.0036 0.016 0.0097
Onchocerca volvulus 0.0267 0.2594 0.4321
Loa Loa (eye worm) MH2 domain-containing protein 0.0036 0.016 0.0211
Schistosoma mansoni tubulin subunit gamma 0.04 0.4002 0.3964
Loa Loa (eye worm) tubulin alpha 2 0.0359 0.3563 0.5272
Toxoplasma gondii isocitrate dehydrogenase 0.0072 0.0537 0.0754
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0031 0.0046
Onchocerca volvulus 0.0046 0.0262 0.041
Schistosoma mansoni hypothetical protein 0.008 0.0619 0.0559
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Echinococcus multilocularis Tubulin beta 2C chain 0.066 0.6742 0.6721
Schistosoma mansoni tubulin subunit delta 0.0174 0.1612 0.1558
Echinococcus multilocularis musashi 0.0119 0.1031 0.0973
Loa Loa (eye worm) hypothetical protein 0.008 0.0619 0.0894
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Echinococcus multilocularis peroxisome assembly protein 26 0.0532 0.5397 0.5367
Trypanosoma brucei beta tubulin 0.04 0.4002 0.5936
Plasmodium falciparum alpha tubulin 2 0.0532 0.5397 0.7996
Echinococcus multilocularis geminin 0.0968 1 1
Brugia malayi Smad1 0.0036 0.016 0.0211
Schistosoma mansoni hypothetical protein 0.0051 0.0321 0.0259
Echinococcus granulosus jun protein 0.0095 0.0776 0.0717
Echinococcus granulosus lamin dm0 0.0119 0.1031 0.0973
Brugia malayi beta-tubulin, identical 0.066 0.6742 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0064 0.0458 0.0397
Treponema pallidum cell division protein FtsZ 0.0174 0.1612 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Trypanosoma brucei alpha tubulin, putative 0.0226 0.2168 0.3216
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0167 0.0222
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0237 0.1375
Mycobacterium leprae putative cytochrome p450 0.0039 0.0193 0.1098
Trichomonas vaginalis tubulin epsilon chain, putative 0.066 0.6742 1
Schistosoma mansoni lamin 0.0119 0.1031 0.0973
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.0167 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0234 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0046 0.0262 0.0363
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0322 0.026
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0989 0.1429
Echinococcus multilocularis mothers against decapentaplegic 5 0.0036 0.016 0.0097
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0203 0.0302
Plasmodium vivax tubulin alpha chain, putative 0.0532 0.5397 0.7996
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0039 0.0193 0.0286
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.05 0.0439
Plasmodium falciparum tubulin beta chain 0.066 0.6742 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0312 0.042
Echinococcus multilocularis Tubulin alpha 1 chain 0.0532 0.5397 0.5367
Brugia malayi Intermediate filament tail domain containing protein 0.0119 0.1031 0.1507
Echinococcus granulosus tubulin beta 1 chain 0.066 0.6742 0.6721
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0322 0.026
Onchocerca volvulus Peroxidasin homolog 0.0587 0.5979 1
Echinococcus multilocularis beta tubulin 0.066 0.6742 0.6721
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0046 0.0262 0.02
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0039 0.0193 0.1098
Echinococcus granulosus neural cadherin 0.0076 0.0579 0.0519
Plasmodium vivax SET domain protein, putative 0.0034 0.0133 0.0153
Echinococcus granulosus fibropellin Ia 0.0076 0.0579 0.0519
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0167 0.0104
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0237 0.0351
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0064 0.0458 0.0397
Leishmania major epsilon tubulin, putative 0.04 0.4002 0.5918
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0046 0.0262 0.0363
Loa Loa (eye worm) cytochrome P450 0.0039 0.0193 0.026
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0046 0.0262 0.0363
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0188 0.0182
Schistosoma mansoni ap endonuclease 0.0064 0.0458 0.0397
Echinococcus granulosus Tubulin beta 2C chain 0.066 0.6742 0.6721
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0312 0.0369
Trypanosoma brucei epsilon tubulin 0.04 0.4002 0.5936
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Loa Loa (eye worm) tubulin beta-2A chain 0.066 0.6742 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0532 0.5397 0.5367
Toxoplasma gondii EGF family domain-containing protein 0.0076 0.0579 0.0818
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Onchocerca volvulus Peroxidase homolog 0.0587 0.5979 1
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0046 0.0262 0.02
Brugia malayi cytochrome P450 0.0039 0.0193 0.026
Leishmania major beta tubulin 0.066 0.6742 1
Leishmania major beta tubulin 0.066 0.6742 1
Trichomonas vaginalis ap endonuclease, putative 0.0064 0.0458 0.0587
Echinococcus granulosus dna polymerase kappa 0.0043 0.0237 0.0174
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0072 0.0537 0.0476
Brugia malayi Tubulin beta chain 0.0174 0.1612 0.2371
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Brugia malayi MH2 domain containing protein 0.0036 0.016 0.0211
Brugia malayi Animal haem peroxidase family protein 0.0587 0.5979 0.8865
Brugia malayi hypothetical protein 0.0266 0.2589 0.3824
Loa Loa (eye worm) hypothetical protein 0.0055 0.036 0.0509
Echinococcus granulosus single minded 2 0.0044 0.0246 0.0184
Schistosoma mansoni hypothetical protein 0.0037 0.0167 0.0104
Loa Loa (eye worm) Smad1 0.0036 0.016 0.0211
Schistosoma mansoni cytochrome P450 0.0039 0.0193 0.013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0262 0.0363
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.05 0.0439
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0057 0.0383 0.0321
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0174 0.1612 0.2316
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0039 0.0193 0.1098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0133 0.007
Echinococcus multilocularis tubulin alpha 0.04 0.4002 0.3964
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0217 0.0154
Schistosoma mansoni thyroid hormone receptor 0.0046 0.0262 0.02
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0167 0.0222
Loa Loa (eye worm) hypothetical protein 0.0034 0.0133 0.0171
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0675 0.0978
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0989 0.0932
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0057 0.0383 0.0321
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.05 0.0439
Trypanosoma brucei unspecified product 0.003 0.0095 0.014
Echinococcus granulosus dna polymerase eta 0.0043 0.0237 0.0174
Echinococcus granulosus FTZ F1 alpha 0.0046 0.0262 0.02
Trichomonas vaginalis tubulin beta chain, putative 0.066 0.6742 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0097 0.0047
Trichomonas vaginalis tubulin alpha chain, putative 0.0226 0.2168 0.3149
Echinococcus granulosus tubulin alpha chain 0.0532 0.5397 0.5367
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0064 0.0458 0.276
Loa Loa (eye worm) intermediate filament protein 0.0119 0.1031 0.1507
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0675 0.0616
Echinococcus multilocularis tubulin alpha 1C chain 0.0532 0.5397 0.5367
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.003 0.008
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0064 0.0068
Onchocerca volvulus 0.0085 0.0675 0.1103
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0237 0.0067
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0064 0.0458 0.0637
Mycobacterium leprae conserved hypothetical protein 0.0024 0.003 0.008
Brugia malayi bHLH-PAS transcription factor 0.0041 0.0206 0.028
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0064 0.0458 0.0654
Brugia malayi Animal haem peroxidase family protein 0.0587 0.5979 0.8865
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0036 0.016 0.0097
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0237 0.0351
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0072 0.0537 0.0754
Plasmodium vivax ataxin-2 like protein, putative 0.0115 0.0989 0.1428
Brugia malayi nuclear hormone receptor 0.0046 0.0262 0.0363
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.05 0.3024
Loa Loa (eye worm) alpha-tubulin 0.0532 0.5397 0.8
Echinococcus multilocularis smad 0.0036 0.016 0.0097
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0579 0.0835
Loa Loa (eye worm) alpha-tubulin 0.0532 0.5397 0.8
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0948 0.089
Echinococcus granulosus tubulin subunit beta 0.066 0.6742 0.6721
Trichomonas vaginalis ap endonuclease, putative 0.0064 0.0458 0.0587
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0072 0.0537 0.3256
Brugia malayi hypothetical protein 0.0115 0.0989 0.1444
Echinococcus multilocularis neural cadherin 0.0076 0.0579 0.0519
Loa Loa (eye worm) steroid hormone receptor 0.0046 0.0262 0.0363
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Loa Loa (eye worm) pax transcription factor protein 2 0.0542 0.55 0.8153
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0312 0.025
Echinococcus granulosus Smad4 0.0036 0.016 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0203 0.0205
Echinococcus granulosus protein jagged 1 0.0076 0.0579 0.0519
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0366 0.0304
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0072 0.0537 0.0525
Brugia malayi steroid hormone receptor 0.0046 0.0262 0.0363
Echinococcus multilocularis jun protein 0.0095 0.0776 0.0717
Brugia malayi hypothetical protein 0.0027 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Schistosoma mansoni tubulin subunit beta 0.066 0.6742 0.6721
Brugia malayi ecdysteroid receptor 0.0046 0.0262 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0203 0.0205
Echinococcus multilocularis tubulin, beta 4A class IVa 0.066 0.6742 0.6721
Echinococcus multilocularis protein patched 0.0048 0.028 0.0218
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0312 0.0182
Brugia malayi Cytochrome P450 family protein 0.0082 0.0646 0.0935
Schistosoma mansoni tubulin subunit beta 0.0174 0.1612 0.1558
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0989 0.1429
Schistosoma mansoni alpha tubulin 0.0532 0.5397 0.5367
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0086 0.0689 0.0999
Trichomonas vaginalis tubulin epsilon chain, putative 0.0532 0.5397 0.7985
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0262 0.02
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0989 0.1216
Brugia malayi notch-like transmembrane receptor 0.0076 0.0579 0.0835
Schistosoma mansoni tubulin subunit alpha 0.0532 0.5397 0.5367
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.0048 0.028 0.0391
Trichomonas vaginalis tubulin epsilon chain, putative 0.0532 0.5397 0.7985
Schistosoma mansoni notch 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Schistosoma mansoni hypothetical protein 0.0046 0.0262 0.02
Echinococcus multilocularis microtubule associated protein 2 0.0777 0.7981 0.7968
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0217 0.0296
Loa Loa (eye worm) cytochrome P450 family protein 0.0117 0.1011 0.1478
Brugia malayi Animal haem peroxidase family protein 0.0587 0.5979 0.8865
Brugia malayi hypothetical protein 0.0074 0.056 0.0806
Schistosoma mansoni tubulin subunit beta 0.066 0.6742 0.6721
Loa Loa (eye worm) tubulin beta chain 0.066 0.6742 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.028 0.0218
Brugia malayi Cytochrome P450 family protein 0.0117 0.1011 0.1478
Schistosoma mansoni tubulin subunit alpha 0.0532 0.5397 0.5367
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0046 0.0262 0.0363
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Trichomonas vaginalis tubulin beta chain, putative 0.0226 0.2168 0.3149
Echinococcus multilocularis neurogenic locus notch protein 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0532 0.5397 0.8
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0086 0.0689 0.4211
Brugia malayi nuclear receptor RXR 0.0027 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.2252 0.3323
Brugia malayi Tubulin beta chain 0.0226 0.2168 0.3198
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Brugia malayi Tubulin beta-1 chain 0.066 0.6742 1
Schistosoma mansoni smad1 5 8 and 0.0036 0.016 0.0097
Trypanosoma cruzi zeta tubulin, putative 0.0174 0.1612 0.2167
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0989 0.0932
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0072 0.0537 0.0754
Brugia malayi Steroid receptor seven-up type 2 0.0046 0.0262 0.0363
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0064 0.0449 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Trypanosoma brucei epsilon tubulin 0.04 0.4002 0.5936
Entamoeba histolytica hypothetical protein 0.0158 0.1449 0.2114
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0097 0.0047
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0039 0.0193 0.1098
Trypanosoma brucei PAB1-binding protein , putative 0.0115 0.0989 0.1466
Leishmania major beta tubulin 0.066 0.6742 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0064 0.0458 0.0404
Onchocerca volvulus 0.0041 0.0206 0.0316
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0322 0.0452
Entamoeba histolytica hypothetical protein 0.0158 0.1449 0.2114
Loa Loa (eye worm) hypothetical protein 0.0116 0.1008 0.1472
Loa Loa (eye worm) BEN-1 protein 0.066 0.6742 1
Mycobacterium ulcerans cell division protein FtsZ 0.0174 0.1612 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.003 0.008
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0113 0.0966 0.0909
Trypanosoma cruzi tubulin delta chain 0.0174 0.1612 0.2167
Brugia malayi hypothetical protein 0.0137 0.1225 0.1795
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.1612 0.2316
Echinococcus multilocularis neurogenic locus notch protein 4 0.0076 0.0579 0.0519
Brugia malayi Tubulin alpha chain 0.0174 0.1612 0.2371
Schistosoma mansoni hypothetical protein 0.0037 0.0167 0.0104
Echinococcus multilocularis slit 2 protein 0.0076 0.0579 0.0519
Schistosoma mansoni hypothetical protein 0.0046 0.0262 0.02
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.012 0.0057
Giardia lamblia Beta tubulin 0.066 0.6742 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0072 0.0537 0.0754
Schistosoma mansoni hypothetical protein 0.0968 1 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0188 0.0182
Mycobacterium leprae Conserved hypothetical protein 0.0039 0.0193 0.1098
Toxoplasma gondii isocitrate dehydrogenase 0.0072 0.0537 0.0754
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0203 0.0016
Echinococcus granulosus tubulin alpha 0.04 0.4002 0.3964
Entamoeba histolytica tubulin alpha chain, putative 0.0532 0.5397 0.7996
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0312 0.0438
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0039 0.0193 0.1098
Onchocerca volvulus 0.0119 0.1031 0.1699
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0039 0.0193 0.1098
Loa Loa (eye worm) animal heme peroxidase 0.0587 0.5979 0.8865
Echinococcus multilocularis tubulin beta 1 chain 0.066 0.6742 0.6721
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0046 0.0262 0.02
Trichomonas vaginalis tubulin gamma chain, putative 0.066 0.6742 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0237 0.0256
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0322 0.026
Brugia malayi MH2 domain containing protein 0.0036 0.016 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0237 0.0067
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0322 0.0452
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Echinococcus granulosus Tubulin alpha 1 chain 0.0532 0.5397 0.5367
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0989 0.1445
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Plasmodium vivax tubulin beta chain, putative 0.066 0.6742 1
Trypanosoma brucei tubulin gamma chain 0.04 0.4002 0.5936
Echinococcus multilocularis Tubulin alpha 1 chain 0.0532 0.5397 0.5367
Brugia malayi Cell division protein ftsZ 0.0174 0.1612 0.2371
Loa Loa (eye worm) tubulin alpha-2 chain 0.0532 0.5397 0.8
Echinococcus granulosus delta-like protein 1 0.0076 0.0579 0.0519
Trypanosoma brucei beta tubulin 0.066 0.6742 1
Schistosoma mansoni notch 0.0076 0.0579 0.0519
Brugia malayi hypoxia-induced factor 1 0.017 0.1568 0.2305
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0076 0.0579 0.0942
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0133 0.007
Schistosoma mansoni cell polarity protein 0.0076 0.0579 0.0519
Trypanosoma cruzi alpha tubulin, putative 0.0532 0.5397 0.7946
Echinococcus multilocularis tubulin delta chain 0.0174 0.1612 0.1558
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0312 0.025
Echinococcus multilocularis thyroid hormone receptor alpha 0.0046 0.0262 0.02
Loa Loa (eye worm) animal heme peroxidase 0.0587 0.5979 0.8865
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0217 0.0154
Trypanosoma brucei unspecified product 0.003 0.0095 0.014
Entamoeba histolytica tubulin gamma chain 0.04 0.4002 0.5918
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0039 0.0193 0.1098
Toxoplasma gondii alpha-tubulin I, putative 0.0532 0.5397 0.7996
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0046 0.0262 0.041
Giardia lamblia Delta tubulin 0.0174 0.1612 0.2114
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0262 0.0363
Trichomonas vaginalis tubulin epsilon chain, putative 0.066 0.6742 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0039 0.0193 0.1098
Loa Loa (eye worm) tubulin alpha 2 0.0359 0.3563 0.5272
Leishmania major beta tubulin 0.066 0.6742 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0263 0.2559 0.378
Schistosoma mansoni hypothetical protein 0.0058 0.0393 0.0331
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0064 0.0458 0.276
Echinococcus multilocularis lamin dm0 0.0119 0.1031 0.0973
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0351 0.0496
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0039 0.0193 0.1098
Echinococcus granulosus tubulin epsilon chain 0.04 0.4002 0.3964
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0133 0.007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0133 0.0153
Trichomonas vaginalis set domain proteins, putative 0.0267 0.2594 0.3786
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0046 0.0262 0.02
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0167 0.0104
Trichomonas vaginalis tubulin gamma chain, putative 0.0174 0.1612 0.2316
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0257 0.0194
Loa Loa (eye worm) tubulin beta chain 0.0174 0.1612 0.2371
Echinococcus granulosus GPCR family 2 0.0037 0.0167 0.0104
Echinococcus granulosus tubulin delta chain 0.0174 0.1612 0.1558
Schistosoma mansoni notch 0.0076 0.0579 0.0519
Brugia malayi Pax transcription factor protein 2 0.0542 0.55 0.8153
Brugia malayi Animal haem peroxidase family protein 0.0587 0.5979 0.8865
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Brugia malayi hypothetical protein 0.0587 0.5979 0.8865
Loa Loa (eye worm) hypothetical protein 0.0111 0.0948 0.1384
Leishmania major DNA polymerase kappa, putative 0.0043 0.0237 0.0308
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0237 0.0067
Schistosoma mansoni slit 0.0076 0.0579 0.0519
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0312 0.042
Echinococcus granulosus protein jagged 2 0.0076 0.0579 0.0519
Schistosoma mansoni hypothetical protein 0.0158 0.1449 0.1394
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.0237 0.0308
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0948 0.089
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0046 0.0262 0.0363
Trypanosoma cruzi beta tubulin, putative 0.066 0.6742 1
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.05 0.0439
Brugia malayi tubulin alpha chain - mouse 0.0532 0.5397 0.8
Echinococcus granulosus intermediate filament protein 0.0119 0.1031 0.0973
Onchocerca volvulus Dual oxidase homolog 0.0587 0.5979 1
Echinococcus granulosus tumor protein p63 0.0381 0.3794 0.3755
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0532 0.5397 0.7985
Schistosoma mansoni hypothetical protein 0.0046 0.0262 0.02
Schistosoma mansoni intermediate filament proteins 0.0119 0.1031 0.0973
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0046 0.0262 0.0363
Echinococcus multilocularis tubulin subunit beta 0.066 0.6742 0.6721
Onchocerca volvulus 0.0054 0.0351 0.056
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0158 0.1449 0.1394
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0989 0.1216
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0116 0.1008 0.1472
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.0167 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0133 0.007
Plasmodium falciparum tubulin gamma chain 0.04 0.4002 0.5918
Echinococcus granulosus neuropeptide receptor A26 0.0523 0.5294 0.5263
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0989 0.0932
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0064 0.0458 0.0637
Echinococcus granulosus tubulin alpha chain 0.0532 0.5397 0.5367
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0095 0.014
Echinococcus granulosus alpha tubulin 0.0532 0.5397 0.5367
Trichomonas vaginalis tubulin alpha chain, putative 0.04 0.4002 0.5896
Echinococcus multilocularis neuropeptide receptor A26 0.0523 0.5294 0.5263
Loa Loa (eye worm) animal heme peroxidase 0.0587 0.5979 0.8865
Brugia malayi MH2 domain containing protein 0.0531 0.5381 0.7976
Schistosoma mansoni single-minded 0.0055 0.0356 0.0295
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0174 0.1612 0.2357
Loa Loa (eye worm) tubulin alpha 2 0.0132 0.1173 0.1718
Trypanosoma brucei alpha tubulin 0.0532 0.5397 0.8005
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0039 0.0193 0.1098
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0046 0.0262 0.02
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0206 0.1181
Trypanosoma cruzi tubulin gamma chain 0.04 0.4002 0.5817
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0039 0.0193 0.1098
Trichomonas vaginalis tubulin alpha chain, putative 0.0226 0.2168 0.3149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.0001
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0262 0.0363
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0064 0.0458 0.0637
Echinococcus multilocularis tubulin alpha 3 chain 0.0532 0.5397 0.5367
Leishmania major beta tubulin 0.066 0.6742 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.0001
Onchocerca volvulus 0.0076 0.0579 0.0942
Schistosoma mansoni tubulin subunit beta 0.066 0.6742 0.6721
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0579 0.0835
Echinococcus multilocularis FTZ F1 alpha 0.0046 0.0262 0.02
Brugia malayi EGF-like domain containing protein 0.0076 0.0579 0.0835
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0039 0.0193 0.1098
Loa Loa (eye worm) hypothetical protein 0.0357 0.3549 0.5252
Echinococcus multilocularis fibropellin Ia 0.0076 0.0579 0.0519
Toxoplasma gondii LsmAD domain-containing protein 0.0115 0.0989 0.1428
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0175 0.0216
Echinococcus granulosus neurogenic locus protein delta 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0359 0.3563 0.5272
Echinococcus granulosus tubulin alpha 3 chain 0.0532 0.5397 0.5367
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0237 0.0351
Schistosoma mansoni transcription factor LCR-F1 0.0158 0.1449 0.1394
Brugia malayi Cytochrome P450 family protein 0.0039 0.0193 0.026
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0086 0.0689 0.4211
Echinococcus multilocularis protein dispatched 1 0.0054 0.0351 0.0289
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0039 0.0193 0.1098
Schistosoma mansoni steroid hormone receptor ad4bp 0.0046 0.0262 0.02
Loa Loa (eye worm) tubulin beta-1 chain 0.066 0.6742 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0046 0.0262 0.0363
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0072 0.0537 0.0476
Brugia malayi nuclear receptor NHR-88 0.0046 0.0262 0.0363
Onchocerca volvulus Bile acid receptor homolog 0.0046 0.0262 0.041
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0619 0.0894
Schistosoma mansoni hypothetical protein 0.0077 0.0589 0.0529
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0312 0.0438
Trichomonas vaginalis tubulin gamma chain, putative 0.04 0.4002 0.5896
Echinococcus multilocularis Tubulin beta 2C chain 0.066 0.6742 0.6721
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0203 0.0205
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Echinococcus granulosus neurogenic locus notch protein 0.0076 0.0579 0.0519
Loa Loa (eye worm) hypothetical protein 0.0587 0.5979 0.8865
Onchocerca volvulus 0.0034 0.0133 0.0193
Trypanosoma cruzi PAB1-binding protein , putative 0.0115 0.0989 0.1215
Trypanosoma brucei epsilon tubulin 0.04 0.4002 0.5936
Trichomonas vaginalis tubulin gamma chain, putative 0.04 0.4002 0.5896
Loa Loa (eye worm) hypothetical protein 0.0086 0.0689 0.0999
Echinococcus granulosus protein jagged 1 0.0076 0.0579 0.0519
Echinococcus granulosus tubulin alpha chain 0.0532 0.5397 0.5367
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0046 0.0262 0.0363
Echinococcus granulosus Tubulin beta 2C chain 0.066 0.6742 0.6721
Echinococcus granulosus tubulin subunit TubB 0.0532 0.5397 0.5367
Echinococcus granulosus tubulin alpha 3 chain 0.0532 0.5397 0.5367
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Echinococcus granulosus Tubulin beta 2C chain 0.066 0.6742 0.6721
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0095 0.014
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Schistosoma mansoni hypothetical protein 0.0076 0.0579 0.0519
Trichomonas vaginalis tubulin, putative 0.066 0.6742 1
Leishmania major hypothetical protein, conserved 0.0115 0.0989 0.1428
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0989 0.1383
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0039 0.0193 0.1098
Chlamydia trachomatis endonuclease IV 0.0086 0.0689 1
Brugia malayi follicle stimulating hormone receptor 0.0263 0.2559 0.378
Schistosoma mansoni ap endonuclease 0.0064 0.0458 0.0397
Loa Loa (eye worm) tubulin alpha chain 0.0532 0.5397 0.8
Entamoeba histolytica hypothetical protein 0.0158 0.1449 0.2114
Loa Loa (eye worm) hypothetical protein 0.0119 0.1031 0.1507
Echinococcus granulosus mothers against decapentaplegic 5 0.0036 0.016 0.0097
Schistosoma mansoni RAR-like nuclear receptor 0.0046 0.0262 0.02
Loa Loa (eye worm) animal heme peroxidase 0.0587 0.5979 0.8865
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0989 0.1216
Loa Loa (eye worm) hypothetical protein 0.0046 0.0262 0.0363
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0237 0.0326
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0046 0.0262 0.02
Entamoeba histolytica tubulin family protein 0.066 0.6742 1
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.0206 0.0143
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0046 0.0262 0.0363
Giardia lamblia Epsilon tubulin 0.0174 0.1612 0.2114
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0072 0.0537 0.0525
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0064 0.0458 0.0339
Loa Loa (eye worm) hypothetical protein 0.0078 0.0597 0.0861
Schistosoma mansoni patched 1 0.0048 0.028 0.0218
Echinococcus granulosus Niemann Pick C1 protein 0.0158 0.1451 0.1396
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0072 0.0537 0.0476
Brugia malayi Tubulin alpha chain 0.0532 0.5397 0.8
Leishmania major alpha tubulin 0.0532 0.5397 0.7996
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0039 0.0193 0.1098
Echinococcus granulosus tubulin alpha chain 0.0532 0.5397 0.5367
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.05 0.3024
Schistosoma mansoni DNA polymerase eta 0.0043 0.0237 0.0174
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0116 0.1008 0.1472
Echinococcus multilocularis tubulin alpha chain 0.0532 0.5397 0.5367
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0989 0.0932
Echinococcus multilocularis 0.0039 0.0193 0.013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0322 0.026
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0039 0.0193 0.1098
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.0237 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0039 0.0193 0.1098
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0312 0.0463
Schistosoma mansoni microtubule-associated protein tau 0.0777 0.7981 0.7968
Echinococcus granulosus Tubulin beta 2C chain 0.066 0.6742 0.6721
Echinococcus multilocularis tubulin alpha 3 chain 0.0532 0.5397 0.5367
Echinococcus multilocularis Niemann Pick C1 protein 0.0158 0.1451 0.1396
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.05 0.3024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0133 0.007
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0675 0.0616
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0117 0.1011 0.6232
Onchocerca volvulus Protein ultraspiracle homolog 0.0046 0.0262 0.041
Onchocerca volvulus 0.0587 0.5979 1
Schistosoma mansoni peroxidasin 0.0587 0.5979 0.5953
Schistosoma mansoni lamin 0.0119 0.1031 0.0973
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0262 0.0363
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0913 0.9417 0.9413
Loa Loa (eye worm) hypothetical protein 0.0055 0.036 0.0509
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0039 0.0193 0.1098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0262 0.02
Toxoplasma gondii exonuclease III APE 0.0064 0.0458 0.0637
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0237 0.0174
Brugia malayi Blistered cuticle protein 3 0.0587 0.5979 0.8865
Schistosoma mansoni hypothetical protein 0.0037 0.0167 0.0104
Trypanosoma brucei cytochrome P450, putative 0.0117 0.1011 0.15
Trypanosoma brucei tubulin delta chain 0.0174 0.1612 0.2391
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0119 0.1031 0.1507
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0217 0.0296
Echinococcus multilocularis tubulin alpha chain 0.0532 0.5397 0.5367
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0072 0.0537 0.0796
Brugia malayi Calcitonin receptor-like protein seb-1 0.0116 0.1008 0.1472
Treponema pallidum exodeoxyribonuclease (exoA) 0.0064 0.0458 0.2701
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0064 0.0458 0.0637
Trypanosoma brucei zeta tubulin 0.0174 0.1612 0.2391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0175 0.0164
Onchocerca volvulus 0.0154 0.1409 0.2334
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0356 0.0295
Schistosoma mansoni septate junction protein 0.0076 0.0579 0.0519
Plasmodium vivax tubulin alpha chain, putative 0.0532 0.5397 0.7996
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0306 0.3007 0.4405
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0094 0.0042
Onchocerca volvulus 0.0542 0.55 0.9196
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0989 0.1383
Giardia lamblia High cysteine protein 0.0076 0.0579 0.0527
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0312 0.0463
Loa Loa (eye worm) beta-tubulin 0.066 0.6742 1
Echinococcus multilocularis hypothetical protein 0.0532 0.5397 0.5367
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0046 0.0262 0.0363
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.05 0.3024
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0039 0.0193 0.1098
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0039 0.0193 0.1098
Trichomonas vaginalis tubulin, putative 0.0226 0.2168 0.3149
Brugia malayi bZIP transcription factor family protein 0.0095 0.0776 0.1128
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0068
Schistosoma mansoni tubulin subunit alpha 0.0532 0.5397 0.5367
Trypanosoma brucei alpha tubulin 0.0532 0.5397 0.8005
Loa Loa (eye worm) hypothetical protein 0.0092 0.0749 0.1087
Loa Loa (eye worm) hypothetical protein 0.0076 0.0579 0.0835
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0039 0.0193 0.1098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0322 0.026
Plasmodium falciparum ataxin-2 like protein, putative 0.0115 0.0989 0.1428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0237 0.0351
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0046 0.0262 0.02
Toxoplasma gondii beta-tubulin, putative 0.066 0.6742 1
Schistosoma mansoni tubulin subunit alpha 0.0174 0.1612 0.1558
Echinococcus granulosus tubulin beta 4A class IVa 0.066 0.6742 0.6721
Echinococcus multilocularis dna polymerase eta 0.0043 0.0237 0.0174
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0312 0.042
Echinococcus granulosus beta tubulin 0.066 0.6742 0.6721
Echinococcus multilocularis tubulin gamma 1 chain 0.04 0.4002 0.3964

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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