Detailed information for compound 281395

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 399.283 | Formula: C20H21Cl2FO3
  • H donors: 0 H acceptors: 1 LogP: 6.86 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)/C=C(/C=C/C(=C(/C=C/c1c(Cl)cc(c(c1Cl)C)OC)\C)/F)\C
  • InChi: 1S/C20H21Cl2FO3/c1-12(10-19(24)26-5)6-9-17(23)13(2)7-8-15-16(21)11-18(25-4)14(3)20(15)22/h6-11H,1-5H3/b8-7+,9-6+,12-10+,17-13-
  • InChiKey: NBCIZXSVOKGOLA-OWZIPLGFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0003 0.0005
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0114 0.036 0.0528
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0003 0.0009
Schistosoma mansoni multidrug resistance protein 0.0024 0.0035 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.006
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0016 0.0029
Echinococcus granulosus lysine specific demethylase 5A 0.0135 0.0437 0.0791
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0092 0.026
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0368 0.0666
Brugia malayi Cathepsin L-like precursor 0.0036 0.0078 0.022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0011 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0052 0.0076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0326 0.1127 0.1651
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0037 0.0083 0.0083
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0439 0.0644
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.000000000063739
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0679 0.2939
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0077 0.0228 0.0984
Echinococcus granulosus geminin 0.0192 0.0642 0.1163
Trypanosoma brucei metacaspase 0.002 0.0021 0.0031
Echinococcus granulosus cathepsin L 0.0018 0.0015 0.0027
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0071 0.02
Loa Loa (eye worm) hypothetical protein 0.0047 0.0117 0.0333
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0076 0.0076
Trichomonas vaginalis abcb9, putative 0.0024 0.0035 0.0146
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0465 0.163 0.4567
Echinococcus multilocularis pol protein 0.278 1 1
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0035 0.0146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.025 0.0453
Onchocerca volvulus 0.0024 0.0035 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0015 0.0022
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0016 0.0046
Onchocerca volvulus 0.0036 0.0078 0.022
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0035 0.0146
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0078 0.0078
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0092 0.026
Trypanosoma cruzi metacaspase, putative 0.002 0.0021 0.0031
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0096 0.0269
Entamoeba histolytica hypothetical protein 0.0041 0.0096 0.0416
Echinococcus multilocularis caspase 0.002 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Onchocerca volvulus 0.0036 0.0078 0.022
Echinococcus granulosus cathepsin l1 0.0024 0.0035 0.0063
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0096 0.0589
Brugia malayi Death domain containing protein 0.0016 0.0008 0.0021
Trichomonas vaginalis hypothetical protein 0.0209 0.0706 0.3054
Brugia malayi Pre-SET motif family protein 0.0237 0.0805 0.2285
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0181 0.0514
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0368 0.0666
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0021 0.02
Echinococcus granulosus lysine specific demethylase 6a 0.0035 0.0075 0.0136
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0021 0.013
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.01 0.0427
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Leishmania major cathepsin L-like protease 0.0036 0.0078 0.0114
Leishmania major basic transcription factor 3a, putative 0.004 0.0092 0.0135
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0099
Loa Loa (eye worm) hypothetical protein 0.0035 0.0075 0.0214
Schistosoma mansoni survival motor neuron protein 0.0055 0.0146 0.0265
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0078 0.0078
Mycobacterium tuberculosis Conserved protein 0.0041 0.0096 0.0269
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0015 0.0027
Mycobacterium tuberculosis Possible penicillin-binding protein 0.026 0.089 0.2494
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0096 0.1361
Brugia malayi Cathepsin L-like precursor 0.0036 0.0078 0.022
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0096 0.0269
Brugia malayi Cathepsin L-like precursor 0.0024 0.0035 0.0099
Entamoeba histolytica P-glyco protein 6, putative 0.0024 0.0035 0.0152
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0071 0.02
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0071 0.0103
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0037 0.0083 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0003 0.0009
Leishmania major p-glycoprotein 0.0024 0.0035 0.0051
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0003 0.0009
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0092 0.026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0092 0.026
Schistosoma mansoni caspase-7 (C14 family) 0.0067 0.019 0.0344
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0092 0.0092
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0465 0.163 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0092 0.0092
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0181 0.0328
Schistosoma mansoni nuclear hormone receptor 0.004 0.0092 0.0166
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Schistosoma mansoni netrin receptor unc5 0.0016 0.0008 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0092 0.0092
Onchocerca volvulus 0.0024 0.0035 0.0099
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.0208 0.059
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.036 0.1555
Trichomonas vaginalis abcb9, putative 0.0024 0.0035 0.0146
Echinococcus granulosus dnaJ subfamily B 0.0914 0.3252 0.5889
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0092 0.026
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0003 0.0009
Brugia malayi Muscleblind-like protein 0.0334 0.1155 0.3276
Onchocerca volvulus 0.0041 0.0096 0.0272
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0003 0.0009
Schistosoma mansoni microtubule-associated protein tau 0.1541 0.5521 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0114 0.036 0.0528
Brugia malayi beta-lactamase family protein 0.0041 0.0096 0.0272
Leishmania major cathepsin L-like protease 0.0136 0.0439 0.0644
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0114 0.036 0.0528
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0092 0.0092
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0092 0.026
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0021 0.0038
Echinococcus multilocularis cathepsin L 0.0018 0.0015 0.0015
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0092 0.0166
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0035 0.0146
Mycobacterium tuberculosis Conserved hypothetical protein 0.1001 0.3569 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0123 0.0393 0.3713
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0093 0.0285 0.0798
Brugia malayi nuclear receptor RXR 0.0019 0.0016 0.0046
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0003 0.0009
Echinococcus multilocularis pol protein 0.278 1 1
Echinococcus multilocularis caspase 2 0.0067 0.019 0.019
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0037 0.0083 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0003 0.0009
Trypanosoma cruzi cruzipain precursor, putative 0.0136 0.0439 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0092 0.0392
Brugia malayi nuclear receptor NHR-88 0.004 0.0092 0.026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0001 0.000000000063739
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0064 0.0181 0.0512
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.013
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0011 0.002
Onchocerca volvulus 0.0036 0.0078 0.022
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.026 0.2462
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0181 0.0181
Echinococcus granulosus mitogen activated protein kinase 0.0114 0.036 0.0652
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0096 0.0269
Leishmania major metacaspase, putative 0.002 0.0021 0.0031
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0016 0.0046
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0237 0.0805 0.2285
Brugia malayi Uncoordinated protein 44 0.0016 0.0008 0.0021
Brugia malayi hypothetical protein 0.0019 0.0016 0.0046
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0092 0.0166
Loa Loa (eye worm) hypothetical protein 0.0067 0.019 0.0538
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0092 0.026
Echinococcus multilocularis transcription factor btf3 0.004 0.0092 0.0092
Brugia malayi cathepsin L-like precursor 0.0024 0.0035 0.0099
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0025 0.0151
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0015 0.0065
Brugia malayi multidrug resistance protein 3 0.0024 0.0035 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0092 0.026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0096 0.0174
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0093 0.0285 0.0516
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0301 0.0301
Onchocerca volvulus 0.0035 0.0076 0.0215
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0093 0.0285 0.1747
Leishmania major cathepsin L-like protease 0.0036 0.0078 0.0114
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0021 0.006
Echinococcus multilocularis pol protein 0.278 1 1
Brugia malayi jmjC domain containing protein 0.0035 0.0075 0.0214
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0035 0.0146
Giardia lamblia Kinase, CMGC MAPK 0.0114 0.036 0.0372
Onchocerca volvulus 0.0989 0.3525 1
Schistosoma mansoni lipoxygenase 0.0135 0.0438 0.0793
Toxoplasma gondii NAC domain-containing protein 0.004 0.0092 0.0868
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.01 0.0181
Loa Loa (eye worm) beta-lactamase 0.0041 0.0096 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0092 0.026
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0015 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Schistosoma mansoni smdr2 0.0024 0.0035 0.0063
Mycobacterium ulcerans beta-lactamase 0.0041 0.0096 0.0269
Plasmodium falciparum enoyl-acyl carrier reductase 0.0209 0.0706 0.4331
Echinococcus multilocularis cysteine protease 0.0036 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.0738
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.01 0.0146
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0292 0.1006 0.2852
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0301 0.0544
Brugia malayi nuclear hormone receptor 0.0019 0.0016 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0003 0.0009
Brugia malayi prostaglandin transporter 0.0126 0.0405 0.1149
Loa Loa (eye worm) runx1 0.0124 0.0397 0.1127
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0035 0.0146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Brugia malayi jmjC domain containing protein 0.0035 0.0075 0.0214
Plasmodium falciparum basic transcription factor 3b, putative 0.004 0.0092 0.0563
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0008 0.0014
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0093 0.0285 0.1747
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0003 0.0009
Echinococcus multilocularis multidrug resistance protein 1 0.0017 0.0009 0.0009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0015 0.0027
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0021 0.0031
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0228 0.0413
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0209 0.0706 0.4331
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.013
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0097
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.026 0.0738
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0209 0.0706 0.4331
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.000000000063739
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0024 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0208 0.0377
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0209 0.0706 0.1978
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0024 0.0035 0.0215
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0008 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0015 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Echinococcus multilocularis mitogen activated protein kinase 3 0.0114 0.036 0.036
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0055 0.0146 0.0265
Brugia malayi Cytochrome P450 family protein 0.0015 0.0003 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0015 0.0065
Entamoeba histolytica NAD synthetase, putative 0.0093 0.0285 0.1234
Mycobacterium ulcerans hypothetical protein 0.0041 0.0096 0.0269
Schistosoma mansoni hypothetical protein 0.0914 0.3252 0.5889
Echinococcus multilocularis Ankyrin 0.0016 0.0008 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0096 0.0174
Echinococcus multilocularis expressed protein 0.0086 0.026 0.026
Plasmodium vivax vivapain-3 0.0018 0.0015 0.0213
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0209 0.0706 0.4331
Schistosoma mansoni polycystin 1-related 0.0064 0.0181 0.0328
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0046 0.0067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0368 0.0666
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0093 0.0285 0.1229
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0036 0.0078 0.0475
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Echinococcus granulosus Solute carrier organic anion transporter family 0.0126 0.0405 0.0734
Leishmania major hypothetical protein, conserved 0.0041 0.0096 0.0141
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0046 0.0128
Echinococcus multilocularis muscleblind protein 1 0.0334 0.1155 0.1155
Loa Loa (eye worm) hypothetical protein 0.0989 0.3525 1
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0035 0.0146
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0021 0.02
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0092 0.0166
Echinococcus granulosus RUN 0.0064 0.0181 0.0328
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.1006 0.4352
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.01 0.0146
Echinococcus granulosus follistatin 0.0086 0.026 0.0472
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.09 0.3202 0.4693
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0181 0.0181
Loa Loa (eye worm) cytochrome P450 0.0015 0.0003 0.0009
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0035 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0092 0.026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0017 0.0048
Trypanosoma brucei metacaspase 5, putative 0.002 0.0021 0.0031
Brugia malayi hypothetical protein 0.0021 0.0024 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0138
Trichomonas vaginalis taga, putative 0.0024 0.0035 0.0146
Schistosoma mansoni organic anion transporter 0.0126 0.0405 0.0734
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0465 0.163 1
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0092 0.026
Plasmodium vivax vivapain-1 0.0018 0.0015 0.0213
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0096 0.0269
Toxoplasma gondii cathepsin CPL 0.0036 0.0078 0.0733
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0016 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Brugia malayi cytochrome P450 0.0015 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0114 0.036 0.0652
Trypanosoma cruzi NAD+ synthase, putative 0.0093 0.0285 0.0417
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0092 0.026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Brugia malayi MH2 domain containing protein 0.0132 0.0424 0.1203
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0114 0.036 0.0528
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0653 0.2309 1
Brugia malayi hypothetical protein 0.0989 0.3525 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0024 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0092 0.026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Brugia malayi hypothetical protein 0.0268 0.0916 0.2599
Loa Loa (eye worm) agrin synaptic family protein 0.0086 0.026 0.0738
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0096 0.0411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Onchocerca volvulus 0.004 0.0092 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0096 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0086
Onchocerca volvulus 0.0036 0.0078 0.022
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0016 0.0046
Plasmodium vivax unspecified product 0.0018 0.0015 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.000000000063739
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0009 0.0016
Toxoplasma gondii ABC1 family protein 0.0041 0.0096 0.0908
Loa Loa (eye worm) hypothetical protein 0.0064 0.0181 0.0514
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0215
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0015 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Leishmania major cytochrome p450-like protein 0.0034 0.0071 0.0103
Onchocerca volvulus 0.0055 0.0146 0.0414
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Brugia malayi Melibiase family protein 0.0077 0.0228 0.0647
Entamoeba histolytica hypothetical protein 0.0041 0.0096 0.0416
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0036 0.0078 0.022
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0037 0.0083 0.0786
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0046 0.0128
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0301 0.0853
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0003 0.0009
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.09 0.3202 0.4693
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0092 0.0166
Plasmodium vivax metacaspase 1, putative 0.002 0.0021 0.0299
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0099
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0096 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Entamoeba histolytica P-glycoprotein-5 0.0024 0.0035 0.0152
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.0035 0.0099
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0046 0.0067
Treponema pallidum fructose-bisphosphate aldolase 0.0653 0.2309 1
Onchocerca volvulus 0.0064 0.0181 0.0514
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0035 0.0035
Schistosoma mansoni GMP synthetase 0.0037 0.0083 0.0151
Onchocerca volvulus Cathepsin F homolog 0.0036 0.0078 0.022
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0092 0.026
Mycobacterium ulcerans NAD synthetase 0.0093 0.0285 0.0798
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0003 0.0009
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.026 0.0738
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.01 0.0433
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Toxoplasma gondii hypothetical protein 0.0307 0.1057 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0096 0.0269
Leishmania major hypothetical protein, conserved 0.0029 0.0052 0.0076
Trypanosoma cruzi NAD+ synthase, putative 0.0093 0.0285 0.0417
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0131 0.0424 0.0767
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0035 0.01
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0035 0.0147
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0003 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0015 0.0022
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0116 0.0368 0.0368
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0092 0.0166
Echinococcus granulosus cysteine protease 0.0018 0.0015 0.0027
Onchocerca volvulus 0.0126 0.0405 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.036 0.0652
Brugia malayi beta-lactamase family protein 0.0041 0.0096 0.0272
Mycobacterium ulcerans GMP synthase 0.0037 0.0083 0.0233
Echinococcus granulosus muscleblind protein 0.0334 0.1155 0.2092
Schistosoma mansoni nuclear receptor 0.0019 0.0016 0.0029
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0024 0.0069
Brugia malayi Cathepsin L-like precursor 0.0036 0.0078 0.022
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Schistosoma mansoni multidrug resistance protein 0.0024 0.0035 0.0063
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0015 0.0003 0.0006
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0035 0.0035
Onchocerca volvulus 0.0036 0.0078 0.022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0075 0.0214
Brugia malayi Cathepsin L-like precursor 0.0036 0.0078 0.022
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0092 0.0092
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0008 0.0021
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.0424 0.1203
Loa Loa (eye worm) jmjC domain-containing protein 0.0135 0.0437 0.1239
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.1006 0.4352
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.012 0.0384 0.1088
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0035 0.0063
Onchocerca volvulus Putative organic anion transporter 0.0126 0.0405 0.1149
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0017 0.0009 0.0033
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0003 0.0009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0016 0.0046
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0015 0.0022
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0092 0.0166
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0035 0.0063
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0016 0.0016
Brugia malayi ecdysteroid receptor 0.004 0.0092 0.026
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0465 0.163 1
Brugia malayi jmjC domain containing protein 0.0135 0.0437 0.1239
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0092 0.0166
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0439 0.0644
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0046 0.0198
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0003 0.0009
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.0035 0.0051
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0092 0.026
Brugia malayi sodium-independent organic anion transporter family protein 0.0126 0.0405 0.1149
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0092 0.026
Echinococcus granulosus cathepsin l1 0.0036 0.0078 0.014
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0056 0.015 0.0272
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.01 0.0146
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0016 0.0029
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0071 0.0103
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0228 0.0413
Schistosoma mansoni lozenge 0.0124 0.0397 0.072
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0016 0.0046
Onchocerca volvulus 0.027 0.0924 0.262
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0035 0.0063
Brugia malayi nuclear receptor NHR-88 0.0019 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0037 0.0083 0.0236
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0052 0.0076
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0015 0.0065
Brugia malayi Cytochrome P450 family protein 0.0034 0.0071 0.02
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0035 0.0152
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0092 0.0092
Echinococcus multilocularis mitogen activated protein kinase 0.0114 0.036 0.036
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0046 0.0128
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0114 0.036 0.3406
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0069
Echinococcus granulosus caspase 8 0.002 0.0021 0.0038
Brugia malayi TAR-binding protein 0.0072 0.0208 0.059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0301 0.0301
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0092 0.0135
Plasmodium falciparum metacaspase-like protein 0.002 0.0021 0.013
Schistosoma mansoni inositol monophosphatase 0.0042 0.01 0.0181
Echinococcus multilocularis muscleblind protein 0.0334 0.1155 0.1155
Onchocerca volvulus 0.0019 0.0016 0.0046
Trypanosoma cruzi MFS transporter, putative 0.0126 0.0405 0.0594
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Schistosoma mansoni thyroid hormone receptor 0.004 0.0092 0.0166
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0078 0.0114
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0021 0.03
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0024 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0025 0.0025
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0003 0.0009
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0003 0.0009
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0039 0.0089 0.016
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0016 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.1006 0.4352
Schistosoma mansoni hypothetical protein 0.0047 0.0117 0.0212
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0465 0.163 0.6647
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.01 0.028
Echinococcus granulosus phd:f box containing protein 0.0035 0.0075 0.0136
Entamoeba histolytica hypothetical protein 0.0041 0.0096 0.0416
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0076 0.0076
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.01 0.0613
Brugia malayi sodium-independent organic anion transporter family protein 0.0126 0.0405 0.1149
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.0035 0.0215
Brugia malayi CXXC zinc finger family protein 0.0064 0.0181 0.0512
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0025 0.0071
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0021 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0016 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.0078 0.022
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0078 0.014
Trypanosoma cruzi metacaspase, putative 0.002 0.0021 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0003 0.0009
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.0035 0.0099
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0096 0.0096
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.0078 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.000000000063739
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0075 0.0214
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0114 0.036 0.0528
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0003 0.0009
Brugia malayi ecdysone receptor 0.0019 0.0016 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.000000000063739
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0024 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0679 0.2939
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0075 0.0214
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0015 0.0043
Schistosoma mansoni lipoxygenase 0.0251 0.0856 0.155
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.0272
Brugia malayi Cytochrome P450 family protein 0.0034 0.0071 0.02
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.0035 0.0152
Onchocerca volvulus 0.0047 0.0117 0.0333
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0003 0.003
Entamoeba histolytica transcription factor BTF3, putative 0.004 0.0092 0.0398
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0003 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0096 0.0411
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0096 0.0269
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0251 0.0856 0.0856
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Brugia malayi steroid hormone receptor 0.004 0.0092 0.026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0064 0.0181 0.0512
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0146 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Echinococcus granulosus microtubule associated protein 2 0.1541 0.5521 1
Loa Loa (eye worm) ctsf protein 0.0036 0.0078 0.022
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1901 0.6823 1
Entamoeba histolytica hypothetical protein 0.0041 0.0096 0.0416
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.000000000063739
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0016 0.0029
Schistosoma mansoni hypothetical protein 0.0192 0.0642 0.1163
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0301 0.0544
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0003 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1901 0.6823 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0015 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.015 0.0425
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0025 0.0045
Echinococcus multilocularis 0.0015 0.0003 0.0003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0131 0.0424 0.0424
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0021 0.0021
Schistosoma mansoni transcription factor btf3 0.004 0.0092 0.0166
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0093 0.0285 0.4034
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0021 0.02
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0017 0.0048
Echinococcus granulosus JmjC domain containing protein 4 0.0035 0.0075 0.0136
Plasmodium vivax GMP synthetase, putative 0.0037 0.0083 0.1177
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Echinococcus multilocularis cpg binding protein 0.0068 0.0194 0.0194
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0001 0.000000000063739
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0035 0.0146
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0003 0.0009
Brugia malayi hypothetical protein 0.0021 0.0024 0.0069
Toxoplasma gondii Alpha-galactosidase 0.0016 0.0008 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0035 0.0146
Brugia malayi Protein kinase domain containing protein 0.0017 0.0011 0.0032
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0035 0.0075 0.0713
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0093 0.0285 0.2694
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0016 0.0029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0035 0.0075 0.0713
Leishmania major mitochondrial DNA polymerase beta 0.1901 0.6823 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0092 0.026
Loa Loa (eye worm) TAR-binding protein 0.0072 0.0208 0.059
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0008 0.0015
Brugia malayi Cathepsin L-like precursor 0.0024 0.0035 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Plasmodium vivax basic transcription factor 3b, putative 0.004 0.0092 0.13
Leishmania major cathepsin L-like protease 0.0136 0.0439 0.0644
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0046 0.0281
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0016 0.0046
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0046 0.0128
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0052 0.0318
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0092 0.0166
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0014
Mycobacterium tuberculosis Conserved protein 0.0041 0.0096 0.0269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0092 0.026
Mycobacterium ulcerans hypothetical protein 0.0027 0.0046 0.0128
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0653 0.2309 1
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0052 0.0735
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0021 0.0038
Schistosoma mansoni organic anion transporter 0.0126 0.0405 0.0734
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0052 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0989 0.3525 1
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0015 0.0027
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.01 0.0944
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Brugia malayi hypothetical protein 0.0126 0.0405 0.1149
Onchocerca volvulus 0.0126 0.0405 0.1149
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.0738
Brugia malayi Cytochrome P450 family protein 0.0056 0.015 0.0425
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0003 0.0009
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0003 0.0009
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0465 0.163 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0092 0.026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0035 0.0146
Onchocerca volvulus 0.0036 0.0078 0.022
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0078 0.022
Plasmodium vivax hypothetical protein, conserved 0.002 0.0021 0.0299
Brugia malayi hypothetical protein 0.0041 0.0096 0.0272
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0037 0.0083 0.0151
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0046 0.013
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.006
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.006
Plasmodium falciparum JmjC domain-containing protein, putative 0.0035 0.0075 0.0462
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0003 0.0009
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0039 0.0089 0.0089
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0046 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0009 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0096 0.0174
Mycobacterium tuberculosis Conserved protein 0.0041 0.0096 0.0269
Echinococcus granulosus cathepsin L cysteine proteinase 0.0036 0.0078 0.014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0368 0.0666
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0092 0.0092
Schistosoma mansoni zinc finger protein 0.0019 0.0016 0.0029
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0016 0.0029
Schistosoma mansoni cpg binding protein 0.0068 0.0194 0.0351
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0096 0.0411
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Loa Loa (eye worm) hypothetical protein 0.0035 0.0075 0.0214
Schistosoma mansoni follistatin 0.0086 0.026 0.0472
Loa Loa (eye worm) RecQ helicase 0.0024 0.0035 0.01
Schistosoma mansoni phd/f-box containing protein 0.0035 0.0075 0.0136
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Brugia malayi nuclear receptor RXR 0.0021 0.0024 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0092 0.0392
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0046 0.0128
Brugia malayi tailless protein 0.0019 0.0016 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0003 0.0009
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0151 0.0495 0.0897
Trypanosoma cruzi metacaspase, putative 0.002 0.0021 0.0031
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0092 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0092 0.026
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0126 0.0405 0.0734
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Leishmania major cathepsin L-like protease 0.0036 0.0078 0.0114
Schistosoma mansoni protein phosphatase 2C 0.0035 0.0075 0.0136
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0016 0.0029
Loa Loa (eye worm) glutaminase 2 0.0309 0.1067 0.3028
Leishmania major cysteine peptidase A (CPA) 0.0036 0.0078 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Onchocerca volvulus Putative organic anion transporter 0.0126 0.0405 0.1149
Loa Loa (eye worm) DR-78 0.0019 0.0016 0.0046
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0003 0.0005
Toxoplasma gondii protease inhibitor PI2 0.0086 0.026 0.2462
Echinococcus granulosus cpg binding protein 0.0068 0.0194 0.0351
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0465 0.163 0.4567
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0076 0.0138
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0301 0.0544
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Echinococcus granulosus cathepsin l cysteine peptidase 0.0036 0.0078 0.014
Schistosoma mansoni hypothetical protein 0.0064 0.0181 0.0328
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0096 0.0272
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.026 0.0738
Plasmodium vivax vivapain-2 0.0036 0.0078 0.1098
Plasmodium falciparum metacaspase 1 0.002 0.0021 0.013
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0096 0.0411
Leishmania major cathepsin L-like protease 0.0036 0.0078 0.0114
Brugia malayi sodium-independent organic anion transporter family protein 0.0126 0.0405 0.1149
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0008 0.0014
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0015 0.0065
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0208 0.0377
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0208 0.0377
Trypanosoma brucei metacaspase MCA3 0.002 0.0021 0.0031
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0116 0.0368 0.0666
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0017 0.0048
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Onchocerca volvulus Putative organic anion transporter 0.0126 0.0405 0.1149
Plasmodium vivax vivapain-2 0.0036 0.0078 0.1098
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.036 0.1555
Schistosoma mansoni glutaminase 0.0309 0.1067 0.1933
Echinococcus multilocularis follistatin 0.0086 0.026 0.026
Mycobacterium leprae putative cytochrome p450 0.0015 0.0003 0.0019
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0035 0.0075 0.0136
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.036 0.1555
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0078 0.033
Schistosoma mansoni multidrug resistance protein 0.0024 0.0035 0.0063
Loa Loa (eye worm) hypothetical protein 0.0126 0.0405 0.1149
Schistosoma mansoni cpg binding protein 0.0064 0.0181 0.0327
Onchocerca volvulus 0.0086 0.026 0.0738
Giardia lamblia Fructose-bisphosphate aldolase 0.0653 0.2309 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0003 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.1006 0.4352
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0024 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0096 0.0272
Brugia malayi Cathepsin L-like precursor 0.0036 0.0078 0.022
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.013 0.042 0.042
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0046 0.0281
Brugia malayi secreted modular calcium-binding protein 1 0.0086 0.026 0.0738
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Echinococcus granulosus transcription factor btf3 0.004 0.0092 0.0166
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0016 0.0029
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0035 0.0146
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0008 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.0424 0.1203
Trypanosoma brucei NAD+ synthase, putative 0.0093 0.0285 0.0417
Schistosoma mansoni coup transcription factor 0.004 0.0092 0.0166
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0015 0.0027
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0008 0.0021
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0035 0.0075 0.011
Leishmania major NAD synthase, putative 0.0093 0.0285 0.0417
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0092 0.0166
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0267 0.0915 0.1342
Echinococcus granulosus survival motor neuron protein 1 0.0268 0.0916 0.166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0008 0.0014
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0092 0.0166
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0071 0.02
Brugia malayi Cell death protein 3 precursor 0.0067 0.019 0.0538
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Brugia malayi nuclear receptor NHR-67 0.0019 0.0016 0.0046
Echinococcus multilocularis JmjC domain containing protein 4 0.0035 0.0075 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0017 0.0048
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0003 0.0009
Echinococcus multilocularis dnaJ subfamily B 0.0914 0.3252 0.3252
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0023
Onchocerca volvulus 0.0126 0.0405 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0092 0.0392
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0035 0.0146
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0078 0.033
Echinococcus multilocularis jumonji domain containing 1A 0.0035 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.0272
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0319 0.1102 0.6758
Brugia malayi jmjC domain containing protein 0.0035 0.0075 0.0214
Mycobacterium ulcerans lipase LipD 0.0041 0.0096 0.0269
Brugia malayi hypothetical protein 0.0018 0.0015 0.0043
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0046 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0092 0.026
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0016 0.0046
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0092 0.0166
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0076 0.0138
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0003 0.0005
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0035 0.0063
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0011 0.002
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0003 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0268 0.0916 0.0916
Echinococcus multilocularis Protein lozenge 0.0124 0.0397 0.0397
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0035 0.0331
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0075 0.0136
Trypanosoma brucei transcription factor BTF3, putative 0.004 0.0092 0.0135
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0096 0.0174
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.006
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.0208 0.059
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0086 0.026 0.0738
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0096 0.0269
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0267 0.0915 0.1342
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0092 0.0166
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0007 0.0101
Echinococcus granulosus tar DNA binding protein 0.0072 0.0208 0.0377
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0035 0.0151
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0092 0.0135
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0096 0.0269
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0035 0.0063
Brugia malayi Cathepsin L-like precursor 0.0036 0.0078 0.022
Plasmodium falciparum cysteine proteinase falcipain 3 0.0036 0.0078 0.0475
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.0272
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0035 0.0035
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0037 0.0083 0.051
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0267 0.0915 0.1342
Echinococcus multilocularis apoptotic protease activating factor 1 0.0047 0.0117 0.0117
Onchocerca volvulus 0.0041 0.0096 0.0272
Brugia malayi conserved hypotetical protein 0.0019 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0181 0.0328
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0046 0.0198
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0092 0.0166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Echinococcus multilocularis RUN 0.0064 0.0181 0.0181
Loa Loa (eye worm) glutaminase 0.0309 0.1067 0.3028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0138
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.026 0.0738
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0035 0.0063
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0015 0.0022
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0126 0.0405 0.1149
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.006
Brugia malayi glutaminase DH11.1 0.0309 0.1067 0.3028
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.01 0.0427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0301 0.0544
Schistosoma mansoni hypothetical protein 0.0192 0.0642 0.1163
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0181 0.1111
Schistosoma mansoni cpg binding protein 0.0068 0.0194 0.0351
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0003 0.0005
Trypanosoma brucei protein kinase, putative 0.0114 0.036 0.0528
Echinococcus multilocularis cysteine protease 0.0036 0.0078 0.0078
Brugia malayi hypothetical protein 0.0029 0.0052 0.0147
Schistosoma mansoni phosphatidylserine receptor 0.0035 0.0075 0.0136
Echinococcus granulosus jumonji domain containing 1A 0.0035 0.0075 0.0136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Brugia malayi jmjC domain containing protein 0.0131 0.0424 0.1202
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.0003 0.0019
Onchocerca volvulus 0.0027 0.0046 0.013
Echinococcus granulosus caspase 0.002 0.0021 0.0038
Toxoplasma gondii transporter, major facilitator family protein 0.0126 0.0405 0.3831
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0003 0.0009
Entamoeba histolytica P-glycoprotein-1 0.0024 0.0035 0.0152
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.0035 0.0496
Schistosoma mansoni inositol monophosphatase 0.0042 0.01 0.0181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Leishmania major cytochrome p450-like protein 0.0015 0.0003 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.1006 0.4352
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0086
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0137 0.0445 0.0806
Schistosoma mansoni nuclear receptor 0.0019 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0084 0.0235
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0003 0.0009
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0209 0.0706 0.1978
Echinococcus multilocularis geminin 0.0192 0.0642 0.0642
Entamoeba histolytica cysteine protease, putative 0.0036 0.0078 0.0336
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0078 0.0336
Brugia malayi hypothetical protein 0.0047 0.0117 0.0333
Schistosoma mansoni hypothetical protein 0.0041 0.0096 0.0174
Trypanosoma brucei metacaspase MCA2 0.002 0.0021 0.0031
Trichomonas vaginalis set domain proteins, putative 0.027 0.0923 0.3995
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.0738
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0319 0.1102 0.3086
Trypanosoma brucei Metacaspase-4 0.002 0.0021 0.0031
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0251 0.0856 0.155
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0035 0.0035
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0035 0.0035
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0078 0.022
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0003 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0021 0.013
Echinococcus multilocularis agrin 0.0086 0.026 0.026
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0036 0.0078 0.0475
Mycobacterium ulcerans glutaminase 0.0309 0.1067 0.299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0301 0.0544
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0267 0.0915 0.1342
Onchocerca volvulus Cell death protein 3 homolog 0.0067 0.019 0.0538
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0092 0.026
Leishmania major cathepsin L-like protease 0.0136 0.0439 0.0644
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0096 0.0141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0052 0.049
Loa Loa (eye worm) hypothetical protein 0.0334 0.1155 0.3276
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0181 0.0181
Echinococcus multilocularis phd:f box containing protein 0.0035 0.0075 0.0075
Trypanosoma cruzi major cysteine proteinase, putative 0.0107 0.0334 0.049
Brugia malayi ABC transporter family protein 0.0024 0.0035 0.0099
Brugia malayi Inositol-1 0.0042 0.01 0.0283
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0016 0.0016
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0021 0.0059
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0084 0.0515
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0071 0.0198
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.026
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0181 0.2565
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0075 0.0214
Schistosoma mansoni jumonji/arid domain-containing protein 0.0135 0.0437 0.0791
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0124 0.0397 0.0582
Schistosoma mansoni rab6-interacting 0.0064 0.0181 0.0328
Brugia malayi hypothetical protein 0.0064 0.0181 0.0514
Schistosoma mansoni thyroid hormone receptor 0.004 0.0092 0.0166
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.01 0.0427
Echinococcus multilocularis lysine specific demethylase 5A 0.0131 0.0424 0.0424
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0292 0.1006 0.2852
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0034 0.0034
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0021 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0046 0.0128
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0035 0.0146
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.006
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0092 0.026
Echinococcus granulosus mitogen activated protein kinase 3 0.0114 0.036 0.0652
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0003 0.0009
Brugia malayi RNA binding protein 0.0072 0.0208 0.059
Echinococcus multilocularis lysine specific demethylase 6a 0.0035 0.0075 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0092 0.026
Brugia malayi MAP kinase sur-1 0.0114 0.036 0.1022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0016 0.0016
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0092 0.0092
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0015 0.0092
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0016 0.0046
Schistosoma mansoni rab6-interacting 0.0064 0.0181 0.0328
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0099
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Brugia malayi hypothetical protein 0.0019 0.0016 0.0046
Trichomonas vaginalis abcb9, putative 0.0024 0.0035 0.0146
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.0272
Brugia malayi jmjC domain containing protein 0.0035 0.0075 0.0214
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.0272
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.036 0.0528
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0046 0.0128
Brugia malayi hypothetical protein 0.0064 0.0181 0.0514
Echinococcus multilocularis caspase 8 0.002 0.0021 0.0021
Schistosoma mansoni jumonji domain containing protein 0.0131 0.0424 0.0767
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Trichomonas vaginalis glutaminase, putative 0.0309 0.1067 0.462
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0076 0.0718
Onchocerca volvulus 0.0019 0.0016 0.0046
Brugia malayi hypothetical protein 0.0126 0.0405 0.1149
Echinococcus granulosus FTZ F1 alpha 0.004 0.0092 0.0166
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.0272
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0006 0.0061
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0092 0.0166
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0016 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0003 0.0009
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.0035 0.0098
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0021 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0138
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0046 0.013
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0035 0.0099
Loa Loa (eye worm) cysteine protease 0.0036 0.0078 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0092 0.026
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0078 0.014
Echinococcus multilocularis microtubule associated protein 2 0.1541 0.5521 0.5521
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0653 0.2309 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0228 0.0647
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.0035 0.0152
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0209 0.0706 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0052 0.0318
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0126 0.0405 0.0405
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0092 0.0166
Leishmania major hypothetical protein, conserved 0.0035 0.0075 0.011
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0092 0.026
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0003 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0046 0.013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0078 0.0078
Loa Loa (eye worm) RNA binding protein 0.0072 0.0208 0.059
Trypanosoma cruzi metacaspase, putative 0.002 0.0021 0.0031
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0071 0.0103
Echinococcus granulosus Ankyrin 0.0016 0.0008 0.0015
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0066 0.012
Loa Loa (eye worm) fibroinase 0.0036 0.0078 0.022
Loa Loa (eye worm) hypothetical protein 0.0064 0.0181 0.0514
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0114 0.036 0.1022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0003 0.0009
Loa Loa (eye worm) inositol-1 0.0042 0.01 0.0283
Mycobacterium ulcerans hypothetical protein 0.1001 0.3569 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.025 0.025
Toxoplasma gondii melibiase subfamily protein 0.0116 0.0368 0.3479
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0209 0.0706 0.6677
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0016 0.0046
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0078 0.0336
Schistosoma mansoni jumonji/arid domain-containing protein 0.0135 0.0437 0.0791
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0096 0.0269
Trichomonas vaginalis esterase, putative 0.0041 0.0096 0.0411
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.026 0.2462
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0015 0.0043
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0024 0.0034 0.0062
Brugia malayi nuclear hormone receptor 0.004 0.0092 0.026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.0008 0.0015
Echinococcus granulosus apoptotic protease activating factor 1 0.0047 0.0117 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.036 0.1555
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0035 0.0147
Brugia malayi Doublecortin family protein 0.0064 0.0181 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0208 0.0377
Loa Loa (eye worm) ICD-1 protein 0.004 0.0092 0.026
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0208 0.0377
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0003 0.0009
Brugia malayi GMP synthase 0.0037 0.0083 0.0236
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Brugia malayi SPARC precursor 0.0086 0.026 0.0738
Plasmodium vivax SET domain protein, putative 0.0035 0.0076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.013
Onchocerca volvulus 0.0064 0.0181 0.0514
Plasmodium vivax JmjC domain containing protein 0.0035 0.0075 0.1067
Schistosoma mansoni loxhd1 0.0064 0.0181 0.0328
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0046 0.0198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0319 0.1102 0.3086
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0096 0.0411
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0003 0.0009
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Echinococcus multilocularis tar DNA binding protein 0.0072 0.0208 0.0208
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0035 0.0152
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0035 0.0035
Leishmania major cytochrome p450-like protein 0.0015 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0046 0.0128
Echinococcus granulosus agrin 0.0086 0.026 0.0472
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.036 0.0528
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0181 0.0328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Onchocerca volvulus 0.0126 0.0405 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0086
Trypanosoma brucei RNA helicase, putative 0.0114 0.036 0.0528
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0035 0.0146
Schistosoma mansoni retinoic acid receptor RXR 0.0151 0.0495 0.0897
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.09 0.3202 0.4693
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0021 0.0086
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0126 0.0405 0.0405
Onchocerca volvulus 0.0036 0.0078 0.022
Brugia malayi Pre-SET motif family protein 0.0035 0.0076 0.0215
Brugia malayi beta-NAC-like protein 0.004 0.0092 0.026
Onchocerca volvulus 0.0126 0.0405 0.1149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0078 0.033
Entamoeba histolytica hypothetical protein 0.004 0.0092 0.0398
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1901 0.6823 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0035 0.0146
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0096 0.0141
Brugia malayi beta-lactamase 0.0041 0.0096 0.0272
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0116 0.0368 0.0368
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0021 0.0086
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.0035 0.0331
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0035 0.0146
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0334 0.1155 0.3276
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0642 0.2777
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0096 0.0096
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.026 0.2462
Mycobacterium leprae Probable lipase LipE 0.0041 0.0096 0.0589
Entamoeba histolytica cysteine protease, putative 0.0018 0.0015 0.0065
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.01 0.0146
Echinococcus granulosus death domain containing protein 0.0016 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0268 0.0916 0.2599
Echinococcus granulosus bloom syndrome protein 0.0024 0.0035 0.0064
Schistosoma mansoni agrin 0.0086 0.026 0.0472
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0021 0.0038
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0075 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Onchocerca volvulus Glucosylceramidase homolog 0.0192 0.0642 0.1821
Schistosoma mansoni cytochrome P450 0.0015 0.0003 0.0006
Echinococcus granulosus caspase 2 0.0067 0.019 0.0344
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0015 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.1006 0.4352
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.0738
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0016 0.0016
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0075 0.011
Onchocerca volvulus 0.0041 0.0096 0.0272
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0078 0.033
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0301 0.0853
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0024 0.0069
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0003 0.0009
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0035 0.0063
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0035 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0439 0.0644
Leishmania major cathepsin L-like protease 0.0036 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0069
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.026 0.2462
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0439 0.0644

Activities

Activity type Activity value Assay description Source Reference
Dose (functional) = 200 mg kg-1 Hypervitaminosis A dose, a measure of toxicity, in mice was determined ChEMBL. 7086825
Dose (functional) = 200 mg kg-1 Hypervitaminosis A dose, a measure of toxicity, in mice was determined ChEMBL. 7086825
Effect (functional) = -64 % Antipapilloma activity was measured in mice as percentage effect by ip administration at the dose of 80 mg/kg/day. ChEMBL. 7086825
Effect (functional) = -64 % Antipapilloma activity was measured in mice as percentage effect by ip administration at the dose of 80 mg/kg/day. ChEMBL. 7086825

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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