Detailed information for compound 401918

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1095.23 | Formula: C58H67FN12O9
  • H donors: 11 H acceptors: 9 LogP: 4.45 Rotable bonds: 37
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCC(=O)NCCC[C@@H](C(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)F)NC(=O)/C=C/c1ccccc1)Cc1ccc(cc1)NC(=N)N)Cc1ccc(cc1)C(=O)c1ccccc1)CCCN=C(N)N
  • InChi: 1S/C58H67FN12O9/c1-2-49(72)64-31-10-16-45(56(79)80)69-52(75)44(15-9-32-65-57(60)61)68-54(77)47(34-37-17-24-41(25-18-37)51(74)40-13-7-4-8-14-40)71-55(78)48(35-39-21-28-43(29-22-39)66-58(62)63)70-53(76)46(33-38-19-26-42(59)27-20-38)67-50(73)30-23-36-11-5-3-6-12-36/h3-8,11-14,17-30,44-48H,2,9-10,15-16,31-35H2,1H3,(H,64,72)(H,67,73)(H,68,77)(H,69,75)(H,70,76)(H,71,78)(H,79,80)(H4,60,61,65)(H4,62,63,66)/b30-23+/t44-,45-,46-,47-,48-/m0/s1
  • InChiKey: VRDQZMXJGZJMPV-HSCDLMQYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans heat shock protein 90 0.003 0.0042 0.0744
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0091 0.0189 0.2235
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0095
Entamoeba histolytica protein kinase, putative 0.0091 0.0188 0.1108
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0033 0.015
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0153 0.1451
Loa Loa (eye worm) MBCTL1 0.0063 0.012 0.0545
Echinococcus multilocularis tumor protein p63 0.0389 0.0904 0.0904
Plasmodium vivax unspecified product 0.0135 0.0293 0.3553
Trypanosoma cruzi polo-like protein kinase, putative 0.0188 0.0422 0.1224
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0091
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0189 0.0854
Trichomonas vaginalis set domain proteins, putative 0.0478 0.1117 0.6641
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0226 0.1344
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0012 0.0052
Toxoplasma gondii cathepsin CPL 0.0019 0.0017 0.0136
Schistosoma mansoni hypothetical protein 0.0024 0.0027 0.0064
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0105 0.0223 0.1535
Loa Loa (eye worm) heat shock protein 90 0.0037 0.006 0.0272
Leishmania major cathepsin L-like protease 0.0019 0.0017 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Giardia lamblia Hypothetical protein 0.0091 0.0189 0.1717
Brugia malayi hypothetical protein 0.0035 0.0055 0.0319
Trypanosoma cruzi heat shock protein, putative 0.0015 0.0007 0.002
Brugia malayi CXXC zinc finger family protein 0.0033 0.005 0.0288
Onchocerca volvulus 0.0057 0.0107 0.0957
Trichomonas vaginalis PIKK family atypical protein kinase 0.0435 0.1015 0.6033
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0189 0.1121
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0068 0.0508
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.007 0.007
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0091 0.0189 0.0458
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0145
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0017 0.0017
Schistosoma mansoni DNA polymerase eta 0.0015 0.0006 0.0013
Plasmodium falciparum LCCL domain-containing protein 0.0354 0.0819 1
Brugia malayi hypothetical protein 0.0019 0.0015 0.0084
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0188 0.0422 0.1152
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0435 0.1015 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0377 0.0874 0.8606
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0024 0.0138
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0016 0.0148
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.006 0.0174
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0007 0.0007
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0122 0.1238
Loa Loa (eye worm) hypothetical protein 0.0354 0.0819 0.3708
Loa Loa (eye worm) hypothetical protein 0.0222 0.0504 0.2282
Schistosoma mansoni endoplasmin 0.0037 0.006 0.0144
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0039 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5453
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0091 0.0189 0.0189
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0017 0.0048
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0147 0.0425
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.003 0.0042 0.0086
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0075
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0169 0.0375 0.2226
Toxoplasma gondii heat shock protein HSP90 0.0037 0.006 0.0591
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Leishmania major protein kinase, putative 0.0016 0.0009 0.0025
Loa Loa (eye worm) heat shock protein 75 0.0015 0.0007 0.0032
Brugia malayi Csnk2b protein 0.0036 0.0056 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0164 0.0365 0.2508
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0023 0.0068
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0015 0.007
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0324 0.1469
Loa Loa (eye worm) hypothetical protein 0.0031 0.0046 0.0207
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0009 0.0026
Echinococcus granulosus intermediate filament protein 0.0026 0.0033 0.0033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0015 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0258 0.059 0.351
Leishmania major cytochrome p450-like protein 0.0019 0.0016 0.0043
Onchocerca volvulus 0.0099 0.0207 0.185
Echinococcus granulosus dna polymerase eta 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0072
Loa Loa (eye worm) hypothetical protein 0.0087 0.0178 0.0808
Schistosoma mansoni cpg binding protein 0.0037 0.0059 0.0142
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0226 0.2178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0109 0.0232 0.1377
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.006 0.0114 0.0114
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0288 0.066 0.3927
Loa Loa (eye worm) phosphatidylinositol 3 0.0933 0.2208 1
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0015 0.0007 0.0063
Plasmodium vivax vivapain-2 0.0019 0.0017 0.0155
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0063 0.012 0.0545
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0315 0.0727 0.6507
Trypanosoma brucei heat shock protein 84, putative 0.0015 0.0007 0.0006
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0713 0.1682 0.4877
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0068 0.0405
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0085 0.0174 0.0423
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0027 0.0034 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0096 0.0572
Entamoeba histolytica hypothetical protein 0.0091 0.0188 0.1108
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0258 0.059 0.351
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0024 0.0024
Mycobacterium ulcerans recombinase A 0.0105 0.0223 0.5944
Loa Loa (eye worm) doublecortin family protein 0.0354 0.0819 0.3708
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0135 0.0293 0.3553
Schistosoma mansoni lipoxygenase 0.108 0.2561 0.6263
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.001 0.002
Brugia malayi 6-phosphofructokinase 0.0107 0.0226 0.1337
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0024 0.0057
Trypanosoma cruzi ISWI complex protein 0.0018 0.0013 0.0036
Schistosoma mansoni survival motor neuron protein 0.0144 0.0317 0.0772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0387 0.0899 0.5347
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.007
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0426 0.0992 0.2425
Echinococcus granulosus expressed conserved protein 0.008 0.0162 0.0162
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0017 0.0117
Plasmodium falciparum casein kinase 2, alpha subunit 0.0135 0.0293 0.3528
Echinococcus granulosus lamin 0.0026 0.0033 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0109 0.0109
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0083 0.0083
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0039 0.0221
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0091 0.0189 0.1933
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.0042 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0091
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.018 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Trypanosoma cruzi polo-like protein kinase, putative 0.0188 0.0422 0.1224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.0874 0.5197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0017 0.0148
Trypanosoma brucei ISWI complex protein 0.0018 0.0013 0.0061
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0226 0.0226
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0288 0.066 0.3927
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0189 0.0854
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0056 0.0608
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0226 0.1344
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0091 0.0189 0.0189
Schistosoma mansoni netrin receptor unc5 0.0014 0.0004 0.0007
Trypanosoma brucei Casein kinase II 0.0135 0.0293 0.2847
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0073 0.0211
Echinococcus granulosus muscleblind protein 0.0146 0.0321 0.0321
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0332 0.0767 0.4558
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0016 0.0072
Echinococcus granulosus death domain containing protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0003
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0039 0.0434
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0426 0.0992 0.2878
Loa Loa (eye worm) hypothetical protein 0.0099 0.0207 0.0936
Schistosoma mansoni lipoxygenase 0.1717 0.4089 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0039 0.1026
Onchocerca volvulus 0.005 0.0091 0.0817
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0017 0.0017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.0189 0.1114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0001 0.0007
Onchocerca volvulus 0.0019 0.0017 0.0148
Giardia lamblia GTOR 0.0435 0.1015 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0169 0.0375 0.2232
Brugia malayi hypothetical protein 0.0019 0.0015 0.0084
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0517 0.121 0.7191
Leishmania major cathepsin L-like protease 0.0073 0.0147 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.0233 0.0529 0.3146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0048 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0031 0.0046 0.0109
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0102 0.0247
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0315 0.0727 0.0727
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0017 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0435 0.1015 0.2767
Brugia malayi Cytochrome P450 family protein 0.0029 0.004 0.0231
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0015 0.007
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0169 0.0375 0.2232
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0016 0.0004
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0085 0.0174 0.0174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0713 0.1682 1
Loa Loa (eye worm) mbt repeat family protein 0.0055 0.0102 0.0462
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0233 0.0529 0.3141
Brugia malayi Cathepsin L-like precursor 0.0019 0.0017 0.0091
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0102 0.0247
Entamoeba histolytica protein kinase rad3, putative 0.0222 0.0504 0.2991
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0007 0.0013
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.006 0.035
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0045
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0188 0.0422 0.0422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0435 0.1015 0.2479
Echinococcus granulosus histone acetyltransferase MYST2 0.0063 0.012 0.012
Brugia malayi hypothetical protein 0.0708 0.167 0.9927
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.006 0.0532
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0422 0.103
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0091 0.0413
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0435 0.1015 0.603
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0015 0.0007 0.0007
Echinococcus multilocularis lipoxygenase domain containing protein 0.0354 0.0819 0.0819
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0073 0.0211
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0153 0.0901
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0056 0.0496
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0091 0.0189 0.0189
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0014 0.0031
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0056 0.0154
Leishmania major phosphatidylinositol 3-kinase, putative 0.0169 0.0375 0.1024
Entamoeba histolytica hypothetical protein 0.0091 0.0189 0.1114
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0039 0.0234
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0154 0.034 0.034
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0222 0.0504 0.0504
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0164 0.0365 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0014 0.0038
Trypanosoma brucei polo-like protein kinase 0.0188 0.0422 0.4125
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0147 0.0425
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0122 0.3041
Brugia malayi SET domain containing protein 0.0014 0.0004 0.0016
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0091 0.0189 0.2265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0083 0.0974
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0315 0.0727 0.3292
Entamoeba histolytica hypothetical protein 0.0595 0.1397 0.8304
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0055 0.032
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0154 0.034 0.034
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0222 0.0504 0.0504
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0017 0.004
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0531 0.1245 0.7402
Giardia lamblia Kinase, PLK 0.0188 0.0422 0.4061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.007
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0026 0.0033 0.0297
Brugia malayi CHD4 protein 0.0015 0.0007 0.0032
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.005 0.0091 0.022
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0153 0.0443
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0068 0.0405
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0109 0.0316
Echinococcus multilocularis voltage dependent calcium channel 0.0031 0.0046 0.0046
Onchocerca volvulus 0.0144 0.0317 0.2836
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5453
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Brugia malayi Hsp90 protein 0.0015 0.0007 0.0035
Echinococcus multilocularis cpg binding protein 0.0037 0.0059 0.0059
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0056 0.0256
Echinococcus granulosus high voltage activated calcium channel beta 0.0085 0.0174 0.0174
Onchocerca volvulus 0.0019 0.0017 0.0148
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0713 0.1682 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0009 0.0026
Trypanosoma brucei RNA helicase, putative 0.0106 0.0223 0.2152
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Toxoplasma gondii target of rapamycin (TOR), putative 0.0413 0.096 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0015 0.0006 0.0031
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0017 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.046
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0014 0.004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0018
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0015 0.0015
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0114 0.0677
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0014 0.0018
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0035
Schistosoma mansoni polycystin 1-related 0.0354 0.0819 0.2
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0037 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0024 0.0057
Giardia lamblia Kinase, CMGC GSK 0.005 0.0091 0.0742
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0014 0.0086
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0083 0.0834
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0226 0.1344
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0091 0.0189 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Leishmania major DNA polymerase eta, putative 0.0015 0.0006 0.0018
Schistosoma mansoni heat shock protein 0.0037 0.006 0.0144
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0226 0.1337
Schistosoma mansoni hypothetical protein 0.0091 0.0189 0.0458
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trichomonas vaginalis PIKK family atypical protein kinase 0.0417 0.0971 0.5775
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0016 0.011
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0169 0.0375 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.003 0.0042 0.1191
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0019 0.0085
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0005 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0014 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.0189 0.1114
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0333 0.077 0.3486
Toxoplasma gondii exonuclease III APE 0.002 0.0017 0.0143
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0009 0.0026
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Schistosoma mansoni cpg binding protein 0.0037 0.0059 0.0142
Loa Loa (eye worm) phosphatidylinositol 3 0.0387 0.0899 0.4072
Loa Loa (eye worm) hypothetical protein 0.0708 0.167 0.756
Plasmodium vivax vivapain-2 0.0019 0.0017 0.0155
Toxoplasma gondii hypothetical protein 0.0019 0.0016 0.013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0034 0.02
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0315 0.0727 0.4319
Giardia lamblia Casein kinase II beta chain 0.0036 0.0056 0.0393
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0288 0.066 0.3927
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Brugia malayi Pre-SET motif family protein 0.0061 0.0116 0.0685
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0175 0.0391 0.1769
Brugia malayi Bromodomain containing protein 0.0092 0.0191 0.1129
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0056 0.0644
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.002
Giardia lamblia Grp94/Hsp90 0.003 0.0042 0.0246
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0105 0.0223 0.0647
Brugia malayi Protein kinase domain containing protein 0.0091 0.0188 0.1108
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0016 0.013
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0055 0.0131
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0263 0.0602 0.5907
Onchocerca volvulus 0.0478 0.1117 1
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.007
Plasmodium vivax multidomain scavenger receptor, putative 0.0354 0.0819 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.0874 0.5197
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0226 0.0226
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0039 0.029
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0017 0.0037
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0197 0.0442 0.1282
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0132 0.0286 0.1295
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0056 0.0608
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0164 0.0365 0.0868
Onchocerca volvulus 0.0091 0.0189 0.1687
Echinococcus granulosus Ankyrin 0.0014 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0258 0.059 0.351
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0015 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0015 0.0035
Echinococcus granulosus glycogen synthase kinase 3 beta 0.005 0.0091 0.0091
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1717 0.4089 0.4089
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0091 0.0189 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0417 0.0971 0.5775
Schistosoma mansoni hypothetical protein 0.005 0.0091 0.022
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0435 0.1015 0.603
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0039 0.0234
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0039 0.0234
Loa Loa (eye worm) hypothetical protein 0.0091 0.0189 0.0854
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0435 0.1015 0.1015
Brugia malayi Muscleblind-like protein 0.0146 0.0321 0.19
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0169 0.0375 0.0915
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Echinococcus granulosus heat shock protein 0.0037 0.006 0.006
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0188 0.0422 0.0422
Echinococcus granulosus lipoxygenase domain containing protein 0.0354 0.0819 0.0819
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0091 0.0189 0.0458
Brugia malayi phosphofructokinase 0.0107 0.0226 0.1337
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0114 0.0677
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0016 0.0072
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0017 0.0107
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0169 0.0375 0.2226
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0015 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0417 0.0971 0.5775
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0031 0.0046 0.0046
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0023 0.004
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0042 0.0121
Loa Loa (eye worm) endoplasmin 0.0037 0.006 0.0272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0031 0.0046 0.0046
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0004 0.0008
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0514 0.1204 0.1204
Schistosoma mansoni endoplasmin 0.0037 0.006 0.0144
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0017 0.0075
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0025 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0237 0.0538 0.3201
Loa Loa (eye worm) acetyltransferase 0.0154 0.0339 0.1535
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.034 0.2024
Mycobacterium leprae conserved hypothetical protein 0.0091 0.0189 0.1296
Echinococcus multilocularis survival motor neuron protein 1 0.0708 0.167 0.167
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.006 0.0114 0.0275
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0015 0.0007 0.0007
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0024 0.011
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0153 0.0153
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Trypanosoma cruzi DNA repair protein, putative 0.0032 0.0048 0.014
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0153 0.0371
Trichomonas vaginalis heat shock protein, putative 0.003 0.0042 0.0249
Trypanosoma cruzi hypothetical protein, conserved 0.145 0.3448 1
Brugia malayi Casein kinase II, alpha chain 0.0135 0.0293 0.1739
Giardia lamblia Phosphatidylinositol 4-kinase 0.0091 0.0189 0.1717
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0091 0.0189 0.1806
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0226 0.602
Onchocerca volvulus 0.0035 0.0055 0.0492
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0122 0.0122
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Echinococcus granulosus polycomb protein SCMH1 0.0055 0.0102 0.0102
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0006 0.0031
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0015 0.0084
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0073 0.0433
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Schistosoma mansoni kinase 0.0097 0.0204 0.0495
Schistosoma mansoni fkbp-rapamycin associated protein 0.0222 0.0504 0.123
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0091 0.0189 0.1933
Onchocerca volvulus 0.0013 0.0001 0.0011
Echinococcus granulosus cathepsin l1 0.0019 0.0017 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0005 0.0031
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0047 0.0083 0.0374
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0387 0.0899 0.2453
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0017 0.004
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1052 0.2493 0.2493
Echinococcus multilocularis protein kinase shaggy 0.005 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0338 0.0781 0.1908
Onchocerca volvulus 0.0354 0.0819 0.733
Leishmania major DNA polymerase kappa, putative 0.0022 0.0023 0.0062
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0056 0.0164
Loa Loa (eye worm) hypothetical protein 0.0081 0.0166 0.075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0031 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.003 0.0042 0.0287
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0015 0.0088
Loa Loa (eye worm) hypothetical protein 0.016 0.0354 0.1604
Onchocerca volvulus 0.0072 0.0143 0.1279
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0015 0.0007 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0024 0.0057
Brugia malayi isocitrate dehydrogenase 0.0018 0.0014 0.0075
Schistosoma mansoni hypothetical protein 0.0331 0.0763 0.1864
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0169 0.0375 0.0375
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0088
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0334 0.0773 0.1887
Echinococcus granulosus dual specificity 0.0091 0.0188 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0222 0.0504 0.2996
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0435 0.1015 0.6033
Trypanosoma cruzi casein kinase II, putative 0.0135 0.0293 0.0851
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0017 0.0117
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0015 0.0035
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0039 0.0434
Leishmania major hypothetical protein, conserved 0.0018 0.0013 0.0034
Echinococcus multilocularis RUN 0.0354 0.0819 0.0819
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0015 0.0015
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1717 0.4089 0.4089
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0017 0.0095
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0091 0.0188 0.0849
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0713 0.1682 1
Schistosoma mansoni rab6-interacting 0.0354 0.0819 0.2
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0122 0.028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0014 0.0014
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0017 0.0017
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.002 0.0119
Loa Loa (eye worm) hypothetical protein 0.0154 0.034 0.1541
Echinococcus granulosus bloom syndrome protein 0.0021 0.002 0.002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0006 0.0029
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0026 0.0034 0.0193
Echinococcus granulosus cathepsin l1 0.0013 0.0001 0.0001
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0034 0.02
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Echinococcus multilocularis high voltage activated calcium channel beta 0.0085 0.0174 0.0174
Brugia malayi Protein kinase domain containing protein 0.0132 0.0286 0.1695
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0091 0.0536
Toxoplasma gondii hypothetical protein 0.0052 0.0096 0.0968
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0015 0.0084
Brugia malayi hypothetical protein 0.0354 0.0819 0.4865
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0014 0.004
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0033 0.019
Trichomonas vaginalis heat shock protein, putative 0.0015 0.0007 0.0042
Loa Loa (eye worm) hypothetical protein 0.0244 0.0555 0.2512
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0713 0.1682 1
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0169 0.0375 0.4558
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0015 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0189 0.1121
Echinococcus multilocularis muscleblind protein 0.0146 0.0321 0.0321
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0012 0.0052
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0048 0.0412
Trypanosoma cruzi heat shock protein 90, putative 0.0037 0.006 0.0174
Toxoplasma gondii hypothetical protein 0.0019 0.0016 0.013
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0063 0.012 0.012
Echinococcus granulosus microtubule associated protein 2 0.0795 0.1878 0.1878
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Brugia malayi Cathepsin L-like precursor 0.0019 0.0017 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0055 0.1121
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0085 0.0174 0.0174
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0135 0.0293 0.1329
Loa Loa (eye worm) phosphatidylinositol 3 0.0197 0.0442 0.2002
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.4181 1 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0056 0.0135
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0014 0.0074
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0017 0.0095
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.0084
Onchocerca volvulus 0.0019 0.0017 0.0148
Toxoplasma gondii ck2 beta subunit 0.0036 0.0056 0.0553
Echinococcus multilocularis heat shock protein 90 0.003 0.0042 0.0042
Echinococcus multilocularis serine protein kinase ATM 0.0237 0.0538 0.0538
Giardia lamblia Kinase, CMGC CK2 0.0135 0.0293 0.277
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0063 0.012 0.0709
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0055 0.0102 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0017 0.0017
Schistosoma mansoni voltage-gated cation channel 0.0031 0.0046 0.0109
Leishmania major heat shock protein, putative 0.0015 0.0007 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0073 0.0211
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0017 0.0148
Loa Loa (eye worm) hypothetical protein 0.0026 0.0033 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1176
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0189 0.2265
Echinococcus multilocularis bloom syndrome protein 0.0021 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0484
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0014 0.0074
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.0462
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0039
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0091 0.0189 0.2235
Leishmania major hypothetical protein, unknown function 0.0091 0.0189 0.0514
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0153 0.0153
Brugia malayi follicle stimulating hormone receptor 0.0235 0.0533 0.3165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0286 0.0656 0.39
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus granulosus serine protein kinase ATM 0.0237 0.0538 0.0538
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Schistosoma mansoni zinc finger protein 0.0018 0.0013 0.0028
Brugia malayi 6-phosphofructokinase 0.0107 0.0226 0.1337
Brugia malayi PHD-finger family protein 0.0034 0.0053 0.0305
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0091 0.0543
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0033 0.015
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0015 0.0015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0144 0.0317 0.1878
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0004 0.0037
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0169 0.0375 0.4537
Echinococcus granulosus casein kinase ii subunit alpha 0.0135 0.0293 0.0293
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0226 0.1023
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0153 0.0691
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0014 0.0014
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0169 0.0375 0.17
Leishmania major cathepsin L-like protease 0.0019 0.0017 0.0045
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Brugia malayi Death domain containing protein 0.0014 0.0004 0.0017
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0169 0.0375 0.366
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0017 0.0103
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.0188 0.0511
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0037 0.0037
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0189 0.0854
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0417 0.0971 0.2649
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0056 0.0505
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0351 0.0812 0.4827
Onchocerca volvulus 0.0091 0.0189 0.1687
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Mycobacterium tuberculosis Conserved hypothetical protein 0.0091 0.0189 0.0441
Loa Loa (eye worm) ctsf protein 0.0019 0.0017 0.0075
Echinococcus multilocularis zinc finger protein 0.0028 0.0038 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0073 0.0211
Entamoeba histolytica casein kinase, putative 0.0135 0.0293 0.1739
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0426 0.0992 0.0992
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.0189 0.1114
Schistosoma mansoni heat shock protein 0.0037 0.006 0.0144
Plasmodium vivax glycogen synthase kinase 3, putative 0.005 0.0091 0.1071
Echinococcus multilocularis endoplasmin 0.003 0.0042 0.0042
Echinococcus granulosus zinc finger protein 0.0028 0.0038 0.0038
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0014 0.0108
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0114 0.0677
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0207 0.1223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5454
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0039 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0131 0.0286 0.1699
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0024 0.011
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.006 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Loa Loa (eye worm) hypothetical protein 0.0044 0.0076 0.0346
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0163 0.0397
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.0004
Echinococcus multilocularis lamin 0.0026 0.0033 0.0033
Echinococcus multilocularis heat shock protein 0.0037 0.006 0.006
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0091 0.0189 0.0189
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1631 0.3882 0.9387
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0337 0.0778 0.4622
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0017 0.0017
Echinococcus granulosus geminin 0.0331 0.0763 0.0763
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Entamoeba histolytica hypothetical protein 0.0237 0.0538 0.3196
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.0056 0.0496
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0016 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5454
Echinococcus multilocularis geminin 0.0331 0.0763 0.0763
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0071
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.005 0.0225
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0015 0.0015
Treponema pallidum heat shock protein 90 0.003 0.0042 0.0323
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0056 0.0644
Echinococcus granulosus dnaJ subfamily B 0.0471 0.1101 0.1101
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0622 0.1464 0.8701
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0015 0.0015
Echinococcus granulosus expressed protein 0.0366 0.0848 0.0848
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0169 0.0375 0.3886
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0015 0.0015
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.0339 0.0339
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0163 0.0397
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0018
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0027 0.0124
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0068 0.0749
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.007 0.007
Loa Loa (eye worm) cysteine protease 0.0019 0.0017 0.0075
Toxoplasma gondii FATC domain-containing protein 0.0237 0.0538 0.559
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0122 0.3041
Echinococcus granulosus protein kinase shaggy 0.005 0.0091 0.0091
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0015 0.0091
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0056 0.0553
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0226 0.055
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0435 0.1015 0.603
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0014 0.0122
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0015 0.0015
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0055 0.0055
Onchocerca volvulus 0.0055 0.0102 0.0914
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0015 0.0035
Brugia malayi intracellular kinase 0.005 0.0091 0.0536
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0017 0.0103
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0091 0.0188 0.1796
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0073 0.0659
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0031 0.0046 0.0046
Brugia malayi Bromodomain containing protein 0.0048 0.0085 0.0498
Echinococcus granulosus SAM and MBT domain containing protein 0.0055 0.0102 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0713 0.1682 0.4877
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0006 0.0013
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0016 0.011
Treponema pallidum fructose-bisphosphate aldolase 0.0337 0.0778 1
Echinococcus multilocularis polycomb protein SCMH1 0.0055 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5454
Entamoeba histolytica hypothetical protein 0.0035 0.0055 0.0319
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.0188 0.0544
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0014 0.0063
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0188 0.0422 0.1912
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0412 0.096 0.9451
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0015 0.0006 0.0013
Schistosoma mansoni hypothetical protein 0.0106 0.0223 0.0544
Echinococcus multilocularis 0.0091 0.0189 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0091
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0017 0.005
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0221 0.0499 0.0499
Onchocerca volvulus 0.0033 0.005 0.0444
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0017 0.0163
Schistosoma mansoni hypothetical protein 0.0354 0.0819 0.2
Brugia malayi Protein kinase domain containing protein 0.0315 0.0727 0.4319
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0056 0.0056
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0017 0.0125
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.004 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0096 0.0572
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus granulosus heat shock protein 90 0.003 0.0042 0.0042
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0122 0.3041
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0056 0.0328
Loa Loa (eye worm) hypothetical protein 0.0051 0.0092 0.0415
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0055 0.0055
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0237 0.0538 0.3196
Onchocerca volvulus 0.0019 0.0017 0.0148
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0235 0.0533 0.2414
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0222 0.0504 0.1461
Giardia lamblia Kinase, CMGC GSK 0.005 0.0091 0.0742
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Brugia malayi SH2 domain containing protein 0.0333 0.077 0.4574
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Echinococcus granulosus lamin dm0 0.0026 0.0033 0.0033
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0226 0.1337
Entamoeba histolytica hypothetical protein 0.0035 0.0055 0.0319
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.006 0.035
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0028 0.0127
Trichomonas vaginalis heat shock protein, putative 0.003 0.0042 0.0249
Echinococcus multilocularis casein kinase ii subunit alpha 0.0135 0.0293 0.0293
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0169 0.0375 0.1089
Loa Loa (eye worm) hypothetical protein 0.0087 0.0178 0.0808
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0018
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0169 0.0375 0.2226
Echinococcus multilocularis cysteine protease 0.0019 0.0017 0.0017
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0017 0.0017
Plasmodium falciparum glycogen synthase kinase 3 0.005 0.0091 0.1037
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1736 0.4135 1
Toxoplasma gondii Hsp90 domain-containing protein 0.0015 0.0007 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0281 0.0644 0.3832
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Plasmodium vivax SET domain protein, putative 0.0061 0.0116 0.1378
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0056 0.0505
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0035 0.0055 0.0319
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0016 0.0004
Echinococcus multilocularis dual specificity 0.0091 0.0188 0.0188
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0039 0.0374
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Leishmania major cathepsin L-like protease 0.0073 0.0147 0.04
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0032 0.0048 0.0414
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.006
Loa Loa (eye worm) hypothetical protein 0.0146 0.0321 0.1452
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0039 0.1026
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0091 0.0536
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0026 0.0034 0.0034
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0288 0.066 0.3922
Loa Loa (eye worm) phosphatidylinositol 3 0.0435 0.1015 0.4594
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0146 0.032 0.1449
Leishmania major protein kinase, putative 0.0016 0.0009 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0116 0.0281
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0048 0.0412
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0039 0.0234
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0114 0.1065
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0006 0.0006
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0146 0.032 0.0928
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0015 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Brugia malayi Serotonin receptor 0.046 0.1074 0.6385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0417 0.0971 0.5775
Chlamydia trachomatis recombinase RecA 0.0105 0.0223 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0288 0.066 0.6487
Echinococcus multilocularis lipoxygenase domain containing protein 0.0354 0.0819 0.0819
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0015 0.0084
Brugia malayi heat shock protein 90 0.0037 0.006 0.035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0017 0.005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0083 0.0495
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Loa Loa (eye worm) hypothetical protein 0.0146 0.0321 0.1452
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0007 0.0039
Schistosoma mansoni heat shock protein 0.0015 0.0007 0.0014
Onchocerca volvulus 0.0099 0.0207 0.185
Brugia malayi intermediate filament protein 0.0026 0.0033 0.019
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0321 0.0321
Onchocerca volvulus 0.0019 0.0017 0.0148
Brugia malayi hypoxia-induced factor 1 0.0148 0.0324 0.1923
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0017 0.0117
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0034 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0399 0.0928 0.5519
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Echinococcus granulosus lipoxygenase domain containing protein 0.0354 0.0819 0.0819
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0435 0.1015 0.1015
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0426 0.0992 0.5898
Trypanosoma brucei unspecified product 0.0036 0.0056 0.0496
Trypanosoma brucei protein kinase, putative 0.005 0.0091 0.0841
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0063 0.012 0.012
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.005 0.0091 0.0249
Loa Loa (eye worm) hypothetical protein 0.0099 0.0207 0.0937
Onchocerca volvulus 0.0019 0.0017 0.0148
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0037 0.0088
Echinococcus multilocularis Polycystic kidney disease protein 0.0354 0.0819 0.0819
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Entamoeba histolytica protein kinase, putative 0.0091 0.0188 0.1108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0091 0.0189 0.0189
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0322 0.0322
Onchocerca volvulus 0.0019 0.0017 0.0148
Schistosoma mansoni cpg binding protein 0.0033 0.005 0.0118
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Echinococcus multilocularis heat shock protein 90 0.0037 0.006 0.006
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0091 0.0543
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0426 0.0992 0.0992
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0031 0.0046 0.0046
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0114 0.1065
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0143 0.0143
Echinococcus multilocularis musashi 0.0026 0.0033 0.0033
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0226 0.0616
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0035
Schistosoma mansoni hypothetical protein 0.0331 0.0763 0.1864
Echinococcus granulosus survival motor neuron protein 1 0.0708 0.167 0.167
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0237 0.0538 0.1561
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0006 0.0006
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0006 0.0031
Schistosoma mansoni zinc finger protein 0.0028 0.0038 0.0089
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0531 0.1245 0.7402
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0221 0.0499 0.0499
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0035
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0015 0.0015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0163 0.0163
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0004 0.0017
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0007 0.003
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1052 0.2493 0.6097
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trichomonas vaginalis heat shock protein, putative 0.003 0.0042 0.0249
Loa Loa (eye worm) gastrulation defective protein 1 0.0128 0.0277 0.1254
Brugia malayi Pre-SET motif family protein 0.042 0.0978 0.5812
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0237 0.0538 0.5277
Echinococcus multilocularis expressed protein 0.0366 0.0848 0.0848
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0004 0.0004
Trypanosoma cruzi target of rapamycin kinase 3 0.0417 0.0971 0.2817
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0017 0.0091
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0245 0.0559 0.5801
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0286 0.1699
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0131 0.0381
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0017 0.0091
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0237 0.0538 0.1314
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0091 0.0413
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0016 0.0046
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0039 0.0398
Echinococcus multilocularis voltage dependent calcium channel 0.0031 0.0046 0.0046
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0226 0.0532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0399 0.0928 0.5519
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0226 0.2743
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0068 0.0397
Giardia lamblia Fructose-bisphosphate aldolase 0.0337 0.0778 0.7629
Echinococcus granulosus Polycystic kidney disease protein 0.0354 0.0819 0.0819
Entamoeba histolytica protein kinase, putative 0.005 0.0091 0.0536
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0169 0.0375 0.2232
Echinococcus granulosus RUN 0.0354 0.0819 0.0819
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0147 0.0425
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0288 0.066 0.1915
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0056 0.0336
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.005 0.0091 0.0917
Plasmodium vivax heat shock protein 90, putative 0.0015 0.0007 0.0038
Echinococcus granulosus cyclin dependent kinase 19 0.0132 0.0286 0.0286
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0073 0.0433
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0073 0.1634
Brugia malayi hypothetical protein 0.016 0.0354 0.21
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0188 0.0456
Echinococcus multilocularis expressed conserved protein 0.008 0.0162 0.0162
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0056 0.0164
Brugia malayi PXA domain containing protein 0.002 0.0019 0.0104
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.0188 0.0544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5453
Entamoeba histolytica hypothetical protein 0.0091 0.0189 0.1114
Leishmania major casein kinase II, putative 0.0135 0.0293 0.08
Schistosoma mansoni protein kinase 0.0135 0.0293 0.0715
Leishmania major phosphatidylinositol 3-kinase, putative 0.0377 0.0874 0.2384
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0417 0.0971 0.9573
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0116 0.1178
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0083 0.0834
Schistosoma mansoni rab6-interacting 0.0354 0.0819 0.2
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.003 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Schistosoma mansoni hypothetical protein 0.0144 0.0317 0.0772
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0014 0.0014
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0015 0.0015
Giardia lamblia DINP protein human, muc B family 0.0022 0.0023 0.0057
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.021 0.0474 0.4575
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0713 0.1682 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0417 0.0971 0.5775
Schistosoma mansoni hypothetical protein 0.0471 0.1101 0.269
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0114 0.033
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.0084
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0055 0.0055
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0014 0.0075
Brugia malayi hypothetical protein 0.0354 0.0819 0.4865
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0226 0.1553
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.006 0.0174
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0091 0.0189 0.1121
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0337 0.0778 0.4622
Toxoplasma gondii histone lysine methyltransferase SET1 0.0071 0.0141 0.144
Echinococcus multilocularis microtubule associated protein 2 0.0795 0.1878 0.1878
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0091 0.0189 0.1933
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0514 0.1204 0.1204
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0031 0.0046 0.0046
Echinococcus granulosus tumor protein p63 0.0389 0.0904 0.0904
Trypanosoma cruzi ISWI complex protein 0.0018 0.0013 0.0036
Onchocerca volvulus 0.0354 0.0819 0.733
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0175 0.0391 0.2318
Brugia malayi mbt repeat family protein 0.0055 0.0102 0.06
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0169 0.0375 0.1024
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0004 0.0016
Echinococcus granulosus cpg binding protein 0.0037 0.0059 0.0059
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.002 0.0112
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.0004
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.002 0.0119
Schistosoma mansoni microtubule-associated protein tau 0.0795 0.1878 0.459
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0169 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0245 0.0559 0.2529
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0017 0.004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0149 0.0149
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0017 0.0017
Toxoplasma gondii CMGC kinase, CK2 family 0.0135 0.0293 0.303
Loa Loa (eye worm) histone methyltransferase 0.0012 0 0.0001
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0026 0.0034 0.0034
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.003 0.0042 0.0114
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0091 0.0189 0.2265
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0039 0.0374
Onchocerca volvulus 0.0026 0.0033 0.0297
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.0007
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0169 0.0375 0.1089
Trypanosoma cruzi DNA repair protein, putative 0.0032 0.0048 0.014
Leishmania major cathepsin L-like protease 0.0019 0.0017 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0017 0.0098
Echinococcus multilocularis Zinc finger, PHD finger 0.0169 0.0375 0.0375
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0147 0.0425
Loa Loa (eye worm) RecQ helicase 0.0021 0.002 0.0091
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0034 0.02
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0315 0.0727 0.0727
Brugia malayi Cathepsin L-like precursor 0.0019 0.0017 0.0091
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0122 0.0122
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.042 0.0978 0.4428
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0016 0.0046
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0226 0.0655
Entamoeba histolytica hypothetical protein 0.0091 0.0189 0.1114
Brugia malayi Cytochrome P450 family protein 0.0019 0.0016 0.0087
Schistosoma mansoni myelin transcription factor 1 myt1 0.0063 0.012 0.0291
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0073 0.1634
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Treponema pallidum recombinase A 0.0105 0.0223 0.2709
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0387 0.0899 0.8856
Leishmania major cathepsin L-like protease 0.0073 0.0147 0.04
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0017 0.0098
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0017 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.007
Schistosoma mansoni intermediate filament proteins 0.0026 0.0033 0.0078
Schistosoma mansoni hypothetical protein 0.0018 0.0013 0.0028
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0435 0.1015 0.2942
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0017 0.0017
Trypanosoma brucei heat shock protein, putative 0.0037 0.006 0.0532
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0338 0.0782 0.4645
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0435 0.1015 0.2767
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0035
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0039 0.0374
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0226 0.1337
Echinococcus multilocularis SAM and MBT domain containing protein 0.0055 0.0102 0.0102
Echinococcus granulosus heat shock protein 90 0.0037 0.006 0.006
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0055 0.0102 0.0914
Brugia malayi Cathepsin L-like precursor 0.0019 0.0017 0.0091
Schistosoma mansoni ap endonuclease 0.002 0.0017 0.0039
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0073 0.0073
Brugia malayi FAT domain containing protein 0.0154 0.034 0.2018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0149 0.0149
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0014 0.0084
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0042 0.0121
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0934 0.2212 0.2212
Echinococcus multilocularis histone acetyltransferase MYST2 0.0063 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0152
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0007 0.0007
Brugia malayi hypothetical protein 0.0099 0.0207 0.1224
Leishmania major phosphatidylinositol kinase, putative 0.0091 0.0189 0.0514
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0056 0.0328
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0127 0.0275 0.2663
Plasmodium vivax hypothetical protein 0.0091 0.0189 0.2265
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0017 0.0017
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0114 0.033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0147 0.139
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0288 0.066 0.3922
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.006 0.0114 0.0114
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0006 0.0019
Echinococcus multilocularis cyclin dependent kinase 19 0.0132 0.0286 0.0286
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0091 0.0189 0.1114
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0226 0.055
Echinococcus granulosus dna polymerase kappa 0.0043 0.0073 0.0073
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0122 0.0295
Brugia malayi polk-prov protein 0.0032 0.0048 0.0278
Loa Loa (eye worm) hypothetical protein 0.0081 0.0163 0.074
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0009 0.0026
Brugia malayi Cathepsin L-like precursor 0.0019 0.0017 0.0091
Echinococcus multilocularis dna polymerase eta 0.0015 0.0006 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0293 0.1739
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.0188 0.1108
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0422 0.2511
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0046 0.0046
Loa Loa (eye worm) fibroinase 0.0019 0.0017 0.0075
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0226 0.1023
Loa Loa (eye worm) phosphatidylinositol kinase 0.0091 0.0189 0.0854
Giardia lamblia Heat shock protein HSP 90-alpha 0.0037 0.006 0.043
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0122 0.0333
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0024 0.0024
Schistosoma mansoni ap endonuclease 0.002 0.0017 0.0039
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0426 0.0992 0.2878
Plasmodium vivax endoplasmin, putative 0.0037 0.006 0.0689
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0435 0.1015 0.2942
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.007
Schistosoma mansoni hypothetical protein 0.0154 0.034 0.083
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0091 0.0189 0.1121
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0076 0.0076
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0189 0.0854
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0354 0.0819 0.3708
Schistosoma mansoni bromodomain containing protein 0.0078 0.0159 0.0385
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.1541 0.3667 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0017 0.0047
Trichomonas vaginalis heat shock protein, putative 0.0037 0.006 0.0357
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0293 0.1745
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0083 0.0495
Brugia malayi serine/threonine-protein kinase plk-2 0.0188 0.0422 0.2505
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0107 0.0259
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0153 0.0443
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0073 0.0659
Schistosoma mansoni hypothetical protein 0.0035 0.0055 0.0131
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0144 0.0349
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0226 0.1344
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0016 0.0093
Trypanosoma brucei Heat shock protein 83, putative 0.0037 0.006 0.0532
Echinococcus multilocularis Ankyrin 0.0014 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0091
Plasmodium vivax heat shock protein, putative 0.0015 0.0007 0.0038
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0114 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0091
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0263 0.0601 0.3575
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0088
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.018 0.018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.0778 0.4626
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0114 0.033
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0039 0.0398
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.0339 0.201
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Leishmania major cathepsin L-like protease 0.0019 0.0017 0.0045
Leishmania major phosphatidylinositol 4-kinase, putative 0.0091 0.0189 0.0514
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0014 0.0108
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0031 0.0046 0.0264
Toxoplasma gondii heat shock protein 90, putative 0.0037 0.006 0.0591
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0073 0.0659
Brugia malayi Cathepsin L-like precursor 0.0019 0.0017 0.0091
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0027 0.0034 0.0067
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0226 0.1023
Schistosoma mansoni lamin 0.0026 0.0033 0.0078
Entamoeba histolytica serine/threonine protein kinase, putative 0.0188 0.0422 0.2505
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0017 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Brugia malayi mbt repeat family protein 0.0055 0.0102 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.0559 0.3322
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0017 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0088
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.005 0.0091 0.0091
Schistosoma mansoni lamin 0.0026 0.0033 0.0078
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.0339 0.0826
Brugia malayi Cytochrome P450 family protein 0.0019 0.0016 0.0087
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0023 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.0727 0.1776
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0031 0.0046 0.0109
Entamoeba histolytica cysteine protease, putative 0.0019 0.0017 0.0091
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.006 0.0532
Loa Loa (eye worm) hypothetical protein 0.0514 0.1204 0.5453
Brugia malayi PAS domain containing protein 0.0048 0.0085 0.0497
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0027 0.0034 0.0528
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.018 0.0438
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0091 0.0189 0.1806
Schistosoma mansoni loxhd1 0.0354 0.0819 0.2
Plasmodium falciparum heat shock protein 90 0.0037 0.006 0.0653
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0091 0.0189 0.0547
Trypanosoma cruzi Heat shock protein 83, putative 0.0037 0.006 0.0174
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0169 0.0375 0.0915
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0091 0.0189 0.0547
Plasmodium vivax heat shock protein 86, putative 0.0037 0.006 0.0689
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1052 0.2493 0.2493
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.0874 0.5197
Schistosoma mansoni hypothetical protein 0.008 0.0162 0.0394
Brugia malayi Doublecortin family protein 0.0354 0.0819 0.4865
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0169 0.0375 0.3886
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Leishmania major phosphatidylinositol kinase related protein, putative 0.0105 0.0223 0.0608
Toxoplasma gondii heat shock protein 75, putative 0.0015 0.0007 0.0037
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0114 0.0677
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0595 0.1397 0.8304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0395 0.0917 0.5454
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0091 0.0189 0.0458
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0039 0.0227
Brugia malayi Endoplasmin precursor 0.0037 0.006 0.035
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0153 0.0901
Echinococcus multilocularis lamin dm0 0.0026 0.0033 0.0033
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0222 0.0504 0.2991
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0122 0.0295
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0105 0.0223 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0017 0.0078
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0056 0.0056
Onchocerca volvulus Serine\/threonine kinase homolog 0.0188 0.0422 0.378
Trichomonas vaginalis endoplasmin, putative 0.0023 0.0025 0.0151
Brugia malayi PXA domain containing protein 0.002 0.0019 0.0104
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164
Entamoeba histolytica hypothetical protein 0.0035 0.0055 0.0319
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0012 0.0052
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0435 0.1015 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0031 0.0046 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0286 0.0697
Echinococcus multilocularis dnaJ subfamily B 0.0471 0.1101 0.1101
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0056 0.0328
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.005 0.0091 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0435 0.1015 0.6033
Echinococcus multilocularis cysteine protease 0.0019 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0017 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.096 0.571
Mycobacterium leprae Conserved hypothetical protein 0.0619 0.1455 1
Echinococcus granulosus single minded 2 0.0035 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.0874 0.5197
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.018 0.018
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0091 0.0189 0.2265
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0153 0.0416
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0143 0.0347
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0085 0.0204
Plasmodium falciparum endoplasmin, putative 0.0023 0.0025 0.0225
Leishmania major cathepsin L-like protease 0.0019 0.0017 0.0045
Schistosoma mansoni single-minded 0.0048 0.0085 0.0204
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0315 0.0727 0.3292
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0143 0.0143
Echinococcus granulosus endoplasmin 0.003 0.0042 0.0042
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0076 0.0076
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0096 0.0572
Loa Loa (eye worm) calcium channel 0.0031 0.0046 0.0207
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0026 0.0034 0.0079
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0017 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0039 0.0234
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0068 0.0197
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0014 0.0014
Leishmania major heat shock protein 83-1 0.0037 0.006 0.0164

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.1 uM Human Thrombin receptor 1 (PAR-1) antagonistic ability to inhibit SFLLRN-NH2 (2.7 uM)-induced platelet aggregation ChEMBL. 10021945
IC50 (functional) = 3.1 uM Human Thrombin receptor 1 (PAR-1) antagonistic ability to inhibit SFLLRN-NH2 (2.7 uM)-induced platelet aggregation ChEMBL. 10021945

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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