Detailed information for compound 428725

Basic information

Technical information
  • TDR Targets ID: 428725
  • Name: 2-[(1R)-1-amino-2-(2,4,5-trifluorophenyl)ethy l]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2 ,4]triazolo[4,3-a]pyrazin-7-yl]pent-4-en-1-on e
  • MW: 447.377 | Formula: C19H19F6N5O
  • H donors: 1 H acceptors: 3 LogP: 1.84 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCC(C(=O)N1CCn2c(C1)nnc2C(F)(F)F)[C@@H](Cc1cc(F)c(cc1F)F)N
  • InChi: 1S/C19H19F6N5O/c1-2-3-11(15(26)7-10-6-13(21)14(22)8-12(10)20)17(31)29-4-5-30-16(9-29)27-28-18(30)19(23,24)25/h2,6,8,11,15H,1,3-5,7,9,26H2/t11?,15-/m1/s1
  • InChiKey: IBMCNISGWCTXGJ-JOPIAHFSSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(1R)-1-amino-2-(2,4,5-trifluorophenyl)ethyl]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-penten-1-one
  • 2-[(1R)-1-azanyl-2-(2,4,5-trifluorophenyl)ethyl]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]pent-4-en-1-one
  • 2-[(1R)-1-amino-2-(2,4,5-trifluorophenyl)ethyl]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[3,4-c]pyrazin-7-yl]pent-4-en-1-one

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dipeptidyl-peptidase 4 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog Get druggable targets OG5_128614 All targets in OG5_128614
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein Get druggable targets OG5_128614 All targets in OG5_128614
Candida albicans dipeptidyl aminopeptidase B Get druggable targets OG5_128614 All targets in OG5_128614
Echinococcus granulosus dipeptidyl aminopeptidaseprotein Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma japonicum ko:K01278 dipeptidyl-peptidase 4, putative Get druggable targets OG5_128614 All targets in OG5_128614
Brugia malayi prolyl oligopeptidase family protein Get druggable targets OG5_128614 All targets in OG5_128614
Candida albicans dipeptidyl aminopeptidase B Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) Get druggable targets OG5_128614 All targets in OG5_128614
Loa Loa (eye worm) prolyl oligopeptidase Get druggable targets OG5_128614 All targets in OG5_128614
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.0513 0.1895
Schistosoma mansoni hypothetical protein 0.0301 0.0569 0.1842
Brugia malayi hypothetical protein 0.0051 0.0067 0.0246
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0053 0.0053
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.005 0.0065 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0135 0.0237 0.0874
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0066 0.0242
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0001 0.0003
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.005 0.0065 0.0238
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0026 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.0231 0.043 0.1588
Echinococcus granulosus chromobox protein 1 0.0071 0.0108 0.0351
Brugia malayi Furin-like cysteine rich region family protein 0.0321 0.0609 0.2253
Brugia malayi mbt repeat family protein 0.0049 0.0063 0.0233
Loa Loa (eye worm) hypothetical protein 0.0251 0.0469 0.1735
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0087 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0045 0.0168
Echinococcus multilocularis thyroid hormone receptor alpha 0.0269 0.0505 0.0505
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Schistosoma mansoni cpg binding protein 0.006 0.0085 0.0276
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0003 0.0011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0028 0.0103
Trichomonas vaginalis tubulin alpha chain, putative 0.0415 0.0798 0.295
Schistosoma mansoni tyrosine kinase 0.0105 0.0177 0.0572
Echinococcus multilocularis tumor protein p63 0.0359 0.0686 0.0686
Trypanosoma brucei alpha tubulin 0.102 0.2013 0.7444
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0168 0.0623
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0135 0.0237 0.0875
Loa Loa (eye worm) patched family protein 0.0037 0.0039 0.0142
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0072 0.0266
Leishmania major beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) tubulin alpha chain 0.102 0.2013 0.7444
Loa Loa (eye worm) patched family protein 0.0037 0.0039 0.0142
Toxoplasma gondii protease inhibitor PI2 0.004 0.0046 0.0171
Brugia malayi Tubulin beta chain 0.0415 0.0798 0.295
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0055 0.018
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0046 0.0171
Brugia malayi nuclear receptor RXR 0.0071 0.0109 0.0401
Leishmania major beta tubulin 0.1364 0.2704 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0104 0.0174 0.0642
Trypanosoma cruzi epsilon tubulin, putative 0.082 0.1611 0.5957
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0026 0.0017 0.0062
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0044 0.0142
Brugia malayi glutathione reductase 0.005 0.0066 0.0244
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0044 0.0044
Onchocerca volvulus Putative organic anion transporter 0.0059 0.0084 0.1044
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0053 0.0195
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0051 0.0067 0.0245
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0104 0.0385
Schistosoma mansoni smad1 5 8 and 0.0034 0.0032 0.0105
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0055 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0061 0.0225
Echinococcus multilocularis nuclear receptor nhr 48 0.0064 0.0093 0.0093
Echinococcus multilocularis integrin alpha ps 0.0073 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0108 0.0399
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.02 0.0741
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus multilocularis Immunoglobulin 0.0022 0.001 0.001
Brugia malayi hypothetical protein 0.0076 0.0118 0.0437
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Schistosoma mansoni cpg binding protein 0.0063 0.0092 0.0299
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Toxoplasma gondii transporter, major facilitator family protein 0.0059 0.0084 0.0311
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.004 0.0046 0.017
Trichomonas vaginalis tubulin alpha chain, putative 0.0415 0.0798 0.295
Echinococcus multilocularis tubulin alpha chain 0.102 0.2013 0.2013
Leishmania major cathepsin L-like protease 0.0068 0.0101 0.0374
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0051 0.019
Schistosoma mansoni hypothetical protein 0.0104 0.0173 0.0562
Leishmania major beta tubulin 0.1364 0.2704 1
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.007 0.0106 0.0393
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0000045726 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0000045726 0.0000045726
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0064 0.0093 0.0343
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0118 0.0383
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0016 0.0234
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Leishmania major cathepsin L-like protease 0.0018 0.0001 0.0003
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0066 0.0244
Echinococcus granulosus chromobox protein 1 0.0071 0.0108 0.0351
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0077 0.0248
Loa Loa (eye worm) fibroinase 0.0018 0.0001 0.0001
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.102 0.2013 0.7444
Echinococcus granulosus cpg binding protein 0.0063 0.0092 0.0299
Brugia malayi Tubulin beta-1 chain 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0135 0.0237 0.0874
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0026 0.0097
Leishmania major beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0083
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.0093 0.0093
Echinococcus granulosus sterol regulatory element binding protein 0.026 0.0486 0.1575
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0135 0.0237 0.0767
Loa Loa (eye worm) tubulin beta-2A chain 0.1364 0.2704 1
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0351 0.0669 0.2473
Brugia malayi MH1 domain containing protein 0.0034 0.0032 0.012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0016 0.0058
Schistosoma mansoni chromobox protein 0.0071 0.0108 0.0351
Echinococcus granulosus smad 0.0034 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0221 0.3302
Trypanosoma cruzi tubulin delta chain 0.0692 0.1354 0.5008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0087 0.1308
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0077 0.0077
Toxoplasma gondii tubulin, putative 0.0054 0.0074 0.0275
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0061 0.0197
Trichomonas vaginalis tubulin alpha chain, putative 0.0765 0.1501 0.5552
Echinococcus granulosus epidermal growth factor receptor 0.0174 0.0315 0.1021
Schistosoma mansoni hypothetical protein 0.1555 0.3087 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0001 0.0003
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0176 0.0319 0.1178
Schistosoma mansoni tubulin subunit alpha 0.0351 0.0669 0.2166
Schistosoma mansoni zinc finger protein 0.0064 0.0093 0.0302
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0016 0.0068
Loa Loa (eye worm) prolyl oligopeptidase 0.0209 0.0385 0.1423
Brugia malayi isocitrate dehydrogenase 0.0145 0.0256 0.0947
Echinococcus granulosus roundabout 2 0.0032 0.0029 0.0093
Echinococcus granulosus FTZ F1 alpha 0.0135 0.0237 0.0767
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Onchocerca volvulus 0.0038 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.04
Onchocerca volvulus 0.004 0.0046 0.0571
Echinococcus granulosus neuropeptide receptor A26 0.0501 0.097 0.3142
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0071 0.0109 0.0109
Schistosoma mansoni alpha tubulin 0.102 0.2013 0.6521
Brugia malayi Tubulin alpha-2 chain 0.102 0.2013 0.7444
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0016 0.0058
Loa Loa (eye worm) TK protein kinase 0.0037 0.0039 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Toxoplasma gondii LsmAD domain-containing protein 0.0231 0.043 0.1588
Loa Loa (eye worm) SRC-1 0.0051 0.0068 0.0248
Giardia lamblia Beta tubulin 0.1364 0.2704 1
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.0513 0.1895
Loa Loa (eye worm) MBCTL1 0.0056 0.0077 0.0282
Loa Loa (eye worm) acetyltransferase 0.0153 0.0272 0.1006
Brugia malayi eukaryotic initiation factor 4A 0.0026 0.0017 0.0064
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0145 0.0256 0.1104
Trichomonas vaginalis tubulin beta chain, putative 0.0415 0.0798 0.295
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0089 0.033
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0068 0.0068
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0135 0.0237 0.0767
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus granulosus defective proboscis extension response 0.0022 0.001 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0034
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0061 0.0225
Plasmodium vivax tubulin beta chain, putative 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Treponema pallidum cell division protein FtsZ 0.0351 0.0669 1
Leishmania major beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) glutaminase 2 0.0267 0.0501 0.185
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0765 0.1501 0.5552
Loa Loa (eye worm) hypothetical protein 0.0056 0.0077 0.0282
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0016 0.0234
Loa Loa (eye worm) patched family protein 0.0037 0.0039 0.0142
Loa Loa (eye worm) alpha-tubulin 0.102 0.2013 0.7444
Brugia malayi beta-lactamase family protein 0.0184 0.0334 0.1234
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0001 0.0004
Entamoeba histolytica tubulin alpha chain, putative 0.102 0.2013 0.7444
Echinococcus granulosus peroxisome assembly protein 26 0.102 0.2013 0.6521
Mycobacterium tuberculosis Probable dehydrogenase 0.0115 0.0195 0.0841
Schistosoma mansoni hypothetical protein 0.0035 0.0035 0.0114
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0016 0.0056
Echinococcus multilocularis tyrosine protein kinase Blk 0.0044 0.0053 0.0053
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0032 0.0117
Loa Loa (eye worm) beta-lactamase 0.0184 0.0334 0.1232
Onchocerca volvulus 0.0037 0.0039 0.0476
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0062
Schistosoma mansoni cell adhesion molecule 0.0029 0.0022 0.0072
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.04
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0036 0.0134
Schistosoma mansoni hypothetical protein 0.025 0.0468 0.1514
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0003 0.0015
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0047 0.0175
Brugia malayi hypothetical protein 0.0251 0.0469 0.1736
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0055 0.0205
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0135 0.0237 0.0767
Loa Loa (eye worm) hypothetical protein 0.0054 0.0073 0.0268
Trypanosoma brucei trypanothione reductase 0.005 0.0066 0.0244
Loa Loa (eye worm) hypothetical protein 0.0039 0.0044 0.0161
Trichomonas vaginalis tubulin beta chain, putative 0.1364 0.2704 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0061 0.0224
Loa Loa (eye worm) TK protein kinase 0.0114 0.0193 0.0714
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0032 0.0105
Plasmodium vivax glutathione reductase, putative 0.005 0.0066 0.0244
Echinococcus multilocularis tyrosine protein kinase HCK 0.0037 0.0039 0.0039
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0135 0.0237 0.0767
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0109 0.0352
Plasmodium falciparum tubulin gamma chain 0.0821 0.1612 0.5963
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0184 0.0334 0.1232
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0106 0.0391
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0071 0.0109 0.04
Trypanosoma brucei epsilon tubulin 0.082 0.1611 0.5957
Trichomonas vaginalis esterase, putative 0.0184 0.0334 0.1234
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.0264 0.0854
Loa Loa (eye worm) tubulin beta chain 0.0351 0.0669 0.2472
Echinococcus granulosus Tubulin alpha 1 chain 0.102 0.2013 0.6521
Echinococcus granulosus twitchin 0.0025 0.0016 0.0052
Echinococcus multilocularis expressed conserved protein 0.0568 0.1106 0.1106
Loa Loa (eye worm) integrin beta-2 0.0333 0.0633 0.234
Echinococcus granulosus Solute carrier organic anion transporter family 0.0059 0.0084 0.0272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Schistosoma mansoni RAR-like nuclear receptor 0.0135 0.0237 0.0767
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0135 0.0237 0.0237
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0044 0.0163
Loa Loa (eye worm) TK/INSR protein kinase 0.0105 0.0177 0.0651
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0106 0.0106
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0184 0.0334 0.4989
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.0513 0.1895
Schistosoma mansoni coup transcription factor 0.0135 0.0237 0.0767
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0025 0.0016 0.0053
Brugia malayi Protein kinase domain containing protein 0.0105 0.0177 0.0653
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0061 0.0225
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0053 0.0196
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0016 0.0058
Brugia malayi prostaglandin transporter 0.0059 0.0084 0.0311
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0134 0.0234 0.0234
Echinococcus granulosus tyrosine kinase 0.0044 0.0053 0.0173
Loa Loa (eye worm) hypothetical protein 0.0069 0.0104 0.0383
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0016 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0001 0.0003
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.005 0.0065 0.0965
Schistosoma mansoni tubulin subunit beta 0.1364 0.2704 0.876
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.005 0.0065 0.0238
Leishmania major beta tubulin 0.1364 0.2704 1
Schistosoma mansoni thyroid hormone receptor 0.0269 0.0505 0.1637
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0145 0.0256 0.0256
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0022 0.007
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0026 0.0085
Plasmodium falciparum tubulin epsilon chain, putative 0.082 0.1611 0.5957
Trypanosoma brucei zeta tubulin 0.0921 0.1815 0.671
Toxoplasma gondii patched family protein 0.0037 0.0039 0.0143
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0692 0.1354 0.5008
Echinococcus granulosus beta tubulin 0.1364 0.2704 0.876
Loa Loa (eye worm) tubulin alpha 2 0.067 0.1309 0.4841
Schistosoma mansoni nuclear receptor nhr-48 0.0064 0.0093 0.0302
Toxoplasma gondii patched family protein 0.0037 0.0039 0.0143
Brugia malayi Tubulin alpha-2 chain 0.102 0.2013 0.7444
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0000045726 0.0001
Schistosoma mansoni tyrosine kinase 0.0225 0.0417 0.135
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0003 0.0043
Schistosoma mansoni single-minded 0.0052 0.0069 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Mycobacterium ulcerans beta-lactamase 0.0184 0.0334 0.4989
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0016 0.0059
Plasmodium falciparum eukaryotic initiation factor 4A 0.0026 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.04
Leishmania major gamma-tubulin 0.0821 0.1612 0.5963
Loa Loa (eye worm) alpha-tubulin 0.102 0.2013 0.7444
Echinococcus granulosus tubulin alpha 0.0765 0.1501 0.4864
Echinococcus granulosus Tubulin alpha 1 chain 0.102 0.2013 0.6521
Schistosoma mansoni hypothetical protein 0.0032 0.0029 0.0095
Echinococcus multilocularis Immunoglobulin 0.0022 0.001 0.001
Echinococcus multilocularis sterol regulatory element binding protein 0.026 0.0486 0.0486
Trypanosoma brucei alpha tubulin, putative 0.0415 0.0798 0.295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0041 0.0153
Trichomonas vaginalis tubulin, putative 0.0415 0.0798 0.295
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0135 0.0237 0.0875
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0106 0.039
Leishmania major beta tubulin 0.1364 0.2704 1
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0023 0.0083
Echinococcus multilocularis tubulin alpha 3 chain 0.102 0.2013 0.2013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Brugia malayi MH2 domain containing protein 0.0492 0.0953 0.3526
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0135 0.0237 0.0875
Echinococcus multilocularis dnaJ subfamily B 0.0853 0.1678 0.1678
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.007 0.0106 0.0393
Toxoplasma gondii ABC1 family protein 0.0184 0.0334 0.1234
Trichomonas vaginalis glutaminase, putative 0.0267 0.0501 0.1851
Echinococcus granulosus L aminoadipate semialdehyde 0.0176 0.0319 0.1032
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0068 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0013
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0135 0.0237 0.0767
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0135 0.0237 0.0875
Entamoeba histolytica hypothetical protein 0.0076 0.0118 0.0435
Onchocerca volvulus 0.0037 0.0039 0.0476
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0106 0.039
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0221 0.0952
Echinococcus multilocularis neuroglian 0.0025 0.0016 0.0016
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0017 0.0056
Echinococcus granulosus tubulin subunit TubB 0.102 0.2013 0.6521
Echinococcus granulosus tubulin alpha chain 0.102 0.2013 0.6521
Schistosoma mansoni smad1 5 8 and 0.0034 0.0032 0.0105
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0026 0.0017 0.0056
Trichomonas vaginalis tubulin epsilon chain, putative 0.1364 0.2704 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0059 0.0084 0.0311
Schistosoma mansoni hypothetical protein 0.0134 0.0234 0.0757
Brugia malayi Cathepsin L-like precursor 0.0018 0.0001 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Echinococcus multilocularis GPCR, family 2 0.0032 0.0029 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0101 0.0374
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0115 0.0195 0.0841
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0351 0.0669 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Schistosoma mansoni hypothetical protein 0.025 0.0468 0.1514
Schistosoma mansoni chromobox protein 0.0071 0.0108 0.0351
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0026 0.0017 0.0206
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0108 0.04
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0017 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0135 0.0237 0.0237
Trichomonas vaginalis tubulin, putative 0.1364 0.2704 1
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0001 0.0003
Mycobacterium leprae conserved hypothetical protein 0.0184 0.0334 0.4989
Echinococcus granulosus Tubulin beta 2C chain 0.1364 0.2704 0.876
Leishmania major epsilon tubulin, putative 0.082 0.1611 0.5957
Leishmania major beta tubulin 0.1364 0.2704 1
Schistosoma mansoni tubulin subunit beta 0.1364 0.2704 0.876
Trypanosoma cruzi zeta tubulin, putative 0.0921 0.1815 0.671
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0069 0.0223
Trypanosoma brucei beta tubulin 0.0765 0.1501 0.5552
Echinococcus multilocularis Tubulin beta 2C chain 0.1364 0.2704 0.2704
Schistosoma mansoni survival motor neuron protein 0.0051 0.0068 0.022
Loa Loa (eye worm) glutathione reductase 0.005 0.0066 0.0242
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0082
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0061 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0016 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0083
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0044 0.0044
Brugia malayi Fibronectin type III domain containing protein 0.0025 0.0016 0.0059
Brugia malayi Smad1 0.0034 0.0032 0.012
Entamoeba histolytica cysteine protease, putative 0.0018 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0351 0.0669 0.2473
Loa Loa (eye worm) nuclear hormone receptor 0.0064 0.0093 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0135 0.0237 0.0237
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.005 0.0065 0.0965
Trichomonas vaginalis tubulin beta chain, putative 0.102 0.2013 0.7444
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0044 0.0142
Leishmania major cathepsin L-like protease 0.0018 0.0001 0.0003
Brugia malayi hypoxia-induced factor 1 0.016 0.0286 0.1058
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0051 0.0068 0.0068
Echinococcus multilocularis peroxisome assembly protein 26 0.102 0.2013 0.2013
Brugia malayi Cathepsin L-like precursor 0.0018 0.0001 0.0003
Loa Loa (eye worm) nuclear receptor NHR-67 0.0064 0.0093 0.0343
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0001 0.0003
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0032 0.0117
Mycobacterium tuberculosis Probable lipase LipE 0.0184 0.0334 0.1438
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0016 0.0058
Schistosoma mansoni glutaminase 0.0267 0.0501 0.1622
Onchocerca volvulus 0.0176 0.0319 0.3988
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0026 0.0017 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0032 0.0105
Onchocerca volvulus 0.006 0.0085 0.1061
Loa Loa (eye worm) hypothetical protein 0.0605 0.118 0.4364
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0184 0.0334 0.1232
Mycobacterium tuberculosis Conserved protein 0.0184 0.0334 0.1438
Echinococcus granulosus integrin alpha ps 0.0035 0.0035 0.0114
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0001 0.0003
Mycobacterium ulcerans lipase LipD 0.0184 0.0334 0.4989
Brugia malayi tubulin alpha chain - mouse 0.102 0.2013 0.7444
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0344 0.1271
Schistosoma mansoni tubulin subunit alpha 0.102 0.2013 0.6521
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0026 0.0026
Echinococcus multilocularis Tubulin alpha 1 chain 0.102 0.2013 0.2013
Schistosoma mansoni tyrosine kinase 0.0168 0.0303 0.0983
Loa Loa (eye worm) BEN-1 protein 0.1364 0.2704 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0231 0.043 0.1588
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0123 0.0212 0.0783
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0066 0.0066
Echinococcus granulosus integrin alpha 3 0.0125 0.0215 0.0697
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1364 0.2704 0.2704
Echinococcus multilocularis cpg binding protein 0.0063 0.0092 0.0092
Brugia malayi glutaminase DH11.1 0.0267 0.0501 0.1851
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0135 0.0237 0.0875
Brugia malayi Cell division protein ftsZ 0.0351 0.0669 0.2473
Brugia malayi Patched related family protein 12 0.0037 0.0039 0.0143
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0107
Echinococcus granulosus tubulin alpha chain 0.102 0.2013 0.6521
Onchocerca volvulus Protein ultraspiracle homolog 0.0135 0.0237 0.2961
Schistosoma mansoni lamin 0.0029 0.0023 0.0073
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0003 0.0013
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0026 0.0017 0.0064
Trypanosoma brucei hypothetical protein, conserved 0.0184 0.0334 0.1234
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0029 0.0109
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0155 0.0155
Loa Loa (eye worm) tubulin alpha-2 chain 0.102 0.2013 0.7444
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0047 0.0047
Brugia malayi protein C24B5.3 0.0037 0.0039 0.0143
Trichomonas vaginalis penicillin-binding protein, putative 0.0184 0.0334 0.1234
Echinococcus granulosus neuroglian 0.0025 0.0016 0.0052
Brugia malayi hypothetical protein 0.0231 0.043 0.1588
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0018 0 0.0002
Brugia malayi beta-lactamase family protein 0.0184 0.0334 0.1234
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0184 0.0334 0.1234
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0077 0.0077
Echinococcus multilocularis tubulin subunit beta 0.1364 0.2704 0.2704
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0135 0.0237 0.0875
Mycobacterium tuberculosis Probable reductase 0.0115 0.0195 0.0841
Trichomonas vaginalis tubulin beta chain, putative 0.102 0.2013 0.7444
Schistosoma mansoni tyrosine kinase 0.0111 0.0187 0.0606
Plasmodium vivax hypothetical protein, conserved 0.0184 0.0334 0.1234
Echinococcus granulosus tubulin alpha 3 chain 0.102 0.2013 0.6521
Trypanosoma brucei zeta tubulin, putative 0.0921 0.1815 0.671
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0002 0.0007
Mycobacterium tuberculosis Probable esterase LipL 0.0184 0.0334 0.1438
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0051 0.0068 0.0068
Onchocerca volvulus 0.0415 0.0798 1
Leishmania major beta tubulin 0.1364 0.2704 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0232 0.0431 0.0431
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0045 0.0559
Brugia malayi MH1 domain containing protein 0.0019 0.0002 0.0008
Echinococcus granulosus ecdysone induced protein 78C 0.0135 0.0237 0.0767
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0064 0.0093 0.0345
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0057
Echinococcus granulosus tyrosine protein kinase Lyn 0.0051 0.0068 0.0219
Schistosoma mansoni tubulin subunit beta 0.0351 0.0669 0.2166
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0111 0.0187 0.0187
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0059 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Echinococcus granulosus bloom syndrome protein 0.0044 0.0053 0.0171
Trypanosoma cruzi tubulin gamma chain 0.0821 0.1612 0.5963
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0001 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0044 0.0142
Leishmania major beta tubulin 0.1364 0.2704 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.0093 0.0302
Brugia malayi Nuclear hormone receptor E75 0.0064 0.0093 0.0345
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0272 0.1007
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.0093 0.0302
Echinococcus multilocularis beta tubulin 0.1364 0.2704 0.2704
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0237 0.0442 0.1633
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0001 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0087 0.1308
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Schistosoma mansoni integrin alpha-ps 0.0038 0.0041 0.0134
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0068 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0108 0.04
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0042 0.0042
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0001 0.0003
Plasmodium falciparum lipid/sterol:H+ symporter 0.0037 0.0039 0.0143
Schistosoma mansoni tubulin subunit alpha 0.102 0.2013 0.6521
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0058
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0063 0.0781
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0106 0.0343
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0145 0.0256 0.0256
Schistosoma mansoni tyrosine kinase 0.0321 0.0609 0.1974
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0045 0.0168
Schistosoma mansoni isocitrate dehydrogenase 0.0018 0 0.0001
Schistosoma mansoni hypothetical protein 0.0076 0.0118 0.0383
Schistosoma mansoni organic anion transporter 0.0059 0.0084 0.0272
Giardia lamblia Beta tubulin 0.1364 0.2704 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0135 0.0237 0.0237
Brugia malayi mbt repeat family protein 0.0049 0.0063 0.0233
Brugia malayi beta-lactamase 0.0184 0.0334 0.1234
Brugia malayi Cathepsin L-like precursor 0.0018 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0061 0.0225
Echinococcus multilocularis tubulin alpha 0.0765 0.1501 0.1501
Echinococcus multilocularis neuropeptide receptor A26 0.0501 0.097 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.0513 0.1895
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0155 0.0504
Echinococcus multilocularis tubulin gamma 1 chain 0.0821 0.1612 0.1612
Onchocerca volvulus Protein patched homolog 0.0037 0.0039 0.0476
Brugia malayi Nuclear hormone receptor-like 1 0.0135 0.0237 0.0875
Schistosoma mansoni DNA helicase recq5 0.003 0.0026 0.0085
Loa Loa (eye worm) hypothetical protein 0.0176 0.0319 0.1177
Loa Loa (eye worm) tubulin alpha 2 0.0255 0.0477 0.1761
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0059 0.0084 0.0272
Onchocerca volvulus 0.0059 0.0084 0.1044
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0061 0.0225
Brugia malayi orphan nuclear receptor NR2E1 0.0064 0.0093 0.0345
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0061 0.0225
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.067 0.1309 0.4842
Echinococcus granulosus Niemann Pick C1 protein 0.0605 0.118 0.3821
Brugia malayi hypothetical protein 0.0071 0.0109 0.0401
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0209 0.0385 0.1248
Echinococcus multilocularis FTZ F1 alpha 0.0135 0.0237 0.0237
Schistosoma mansoni follistatin 0.004 0.0046 0.015
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0221 0.0952
Leishmania major beta tubulin 0.1364 0.2704 1
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0042 0.0626
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.001 0.0038
Plasmodium falciparum ataxin-2 like protein, putative 0.0231 0.043 0.1588
Echinococcus granulosus Dipeptidyl peptidase 9 0.007 0.0106 0.0344
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0044 0.0142
Trichomonas vaginalis D-aminoacylase, putative 0.0184 0.0334 0.1234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0022 0.0081
Leishmania major beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Schistosoma mansoni vesicular amine transporter 0.0022 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus multilocularis tyrosine protein kinase Srms 0.0044 0.0053 0.0053
Toxoplasma gondii beta-tubulin, putative 0.1364 0.2704 1
Echinococcus granulosus nuclear receptor nhr 48 0.0064 0.0093 0.0302
Plasmodium falciparum alpha tubulin 1 0.102 0.2013 0.7444
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0044 0.0163
Brugia malayi beta-tubulin, identical 0.1364 0.2704 1
Brugia malayi SPARC precursor 0.004 0.0046 0.0171
Toxoplasma gondii cathepsin CPL 0.0018 0.0001 0.0003
Echinococcus multilocularis tubulin delta chain 0.0351 0.0669 0.0669
Loa Loa (eye worm) isocitrate dehydrogenase 0.0145 0.0256 0.0946
Echinococcus multilocularis epidermal growth factor receptor 0.0174 0.0315 0.0315
Echinococcus multilocularis geminin 0.1555 0.3087 0.3087
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0029 0.0029
Trypanosoma cruzi epsilon tubulin, putative 0.082 0.1611 0.5957
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.005 0.0065 0.0238
Echinococcus multilocularis chromobox protein 1 0.0071 0.0108 0.0108
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0064 0.0093 0.0302
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0016 0.0058
Echinococcus granulosus eukaryotic initiation factor 4A 0.0026 0.0017 0.0056
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0063 0.0063
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0068 0.0219
Leishmania major zeta tubulin, putative 0.0921 0.1815 0.671
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0108 0.0183 0.0592
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0135 0.0237 0.0874
Onchocerca volvulus 0.0049 0.0063 0.0781
Echinococcus granulosus tumor protein p63 0.0359 0.0686 0.2222
Entamoeba histolytica tubulin family protein 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Echinococcus granulosus neuropeptide s receptor 0.0501 0.097 0.3142
Echinococcus multilocularis integrin beta 2 0.0247 0.046 0.046
Brugia malayi sodium-independent organic anion transporter family protein 0.0059 0.0084 0.0311
Trypanosoma brucei epsilon tubulin 0.0765 0.1501 0.5552
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0064 0.0093 0.0302
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0044 0.0053 0.0173
Entamoeba histolytica tubulin alpha-1 chain 0.102 0.2013 0.7444
Echinococcus multilocularis chromobox protein 1 0.0071 0.0108 0.0108
Toxoplasma gondii exonuclease III APE 0.0019 0.0003 0.0013
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0087 0.0283
Echinococcus granulosus intermediate filament protein 0.0029 0.0023 0.0073
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0051 0.0068 0.0068
Brugia malayi Tubulin gamma chain 0.0821 0.1612 0.5963
Plasmodium falciparum tubulin beta chain 0.1364 0.2704 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0051 0.0068 0.0219
Brugia malayi nuclear hormone receptor 0.0064 0.0093 0.0345
Schistosoma mansoni smad1 5 8 and 0.0034 0.0032 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0269 0.0505 0.1637
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0174 0.0315 0.1021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0166
Treponema pallidum NADH oxidase 0.0017 0.0000045726 0.0001
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0002 0.0002
Brugia malayi intermediate filament protein 0.0029 0.0023 0.0083
Echinococcus granulosus dnaJ subfamily B 0.0853 0.1678 0.5435
Brugia malayi Patched related family protein 10 0.0037 0.0039 0.0143
Schistosoma mansoni hypothetical protein 0.1555 0.3087 1
Brugia malayi hypothetical protein 0.0054 0.0073 0.027
Echinococcus multilocularis Tubulin beta 2C chain 0.1364 0.2704 0.2704
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.0093 0.116
Trypanosoma brucei beta tubulin 0.1364 0.2704 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1173 0.232 1
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0209 0.0385 0.0385
Echinococcus multilocularis tubulin alpha chain 0.102 0.2013 0.2013
Onchocerca volvulus 0.0059 0.0084 0.1044
Onchocerca volvulus 0.0184 0.0334 0.4176
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0041 0.0153
Treponema pallidum ATP-dependent RNA helicase 0.0026 0.0017 0.0258
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0063 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Brugia malayi hypothetical protein 0.0064 0.0093 0.0345
Trypanosoma brucei beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) tubulin alpha 2 0.067 0.1309 0.4841
Echinococcus multilocularis roundabout 2 0.0032 0.0029 0.0029
Onchocerca volvulus 0.0295 0.0557 0.6981
Echinococcus granulosus integrin beta 2 0.0247 0.046 0.149
Brugia malayi hypothetical protein 0.0037 0.0039 0.0143
Toxoplasma gondii alpha-tubulin I, putative 0.102 0.2013 0.7444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0047 0.0174
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0057
Leishmania major beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus multilocularis Tubulin alpha 1 chain 0.102 0.2013 0.2013
Brugia malayi MH1 domain containing protein 0.0019 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.04
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0031 0.0028 0.0102
Schistosoma mansoni tyrosine kinase 0.0174 0.0315 0.1021
Trichomonas vaginalis D-aminoacylase, putative 0.0184 0.0334 0.1234
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0026 0.0097
Toxoplasma gondii beta tubulin 0.1364 0.2704 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0061 0.0225
Brugia malayi hypothetical protein 0.0025 0.0016 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0046 0.017
Loa Loa (eye worm) hypothetical protein 0.0237 0.0442 0.1632
Onchocerca volvulus Putative organic anion transporter 0.0059 0.0084 0.1044
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0016 0.0058
Schistosoma mansoni agrin 0.004 0.0046 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0184 0.0334 0.1234
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0016 0.0056
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Brugia malayi prolyl oligopeptidase family protein 0.0209 0.0385 0.1424
Leishmania major eukaryotic initiation factor 4a, putative 0.0026 0.0017 0.0064
Schistosoma mansoni smad 0.0034 0.0032 0.0105
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0000045726 0.0001
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.007 0.0106 0.0393
Trypanosoma cruzi PAB1-binding protein , putative 0.0231 0.043 0.1588
Loa Loa (eye worm) hypothetical protein 0.0038 0.0041 0.0151
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0016 0.006
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0026 0.0097
Brugia malayi Probable isocitrate dehydrogenase 0.0018 0 0.0002
Schistosoma mansoni intermediate filament proteins 0.0029 0.0023 0.0073
Brugia malayi hypothetical protein 0.0149 0.0265 0.0979
Loa Loa (eye worm) hypothetical protein 0.0184 0.0334 0.1232
Brugia malayi protein-tyrosine kinase 0.0044 0.0053 0.0198
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0068 0.0219
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0272 0.0272
Entamoeba histolytica protein kinase, putative 0.0037 0.0039 0.0143
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0018 0 0.0007
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.007 0.0106 0.0393
Echinococcus granulosus GPCR family 2 0.0032 0.0029 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0135 0.0237 0.0237
Brugia malayi photoreceptor-specific nuclear receptor 0.0135 0.0237 0.0875
Echinococcus multilocularis tyrosine protein kinase Abl 0.0104 0.0174 0.0174
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0093 0.0302
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0077 0.0248
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0063 0.0204
Plasmodium vivax vivapain-2 0.0018 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Echinococcus granulosus expressed conserved protein 0.0568 0.1106 0.3583
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0000045726 0.0001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0061 0.0225
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.0513 0.1895
Echinococcus multilocularis expressed protein 0.004 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0231 0.043 0.1587
Echinococcus granulosus epidermal growth factor receptor 0.0321 0.0609 0.1974
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0003 0.0052
Leishmania major eukaryotic initiation factor 4a, putative 0.0026 0.0017 0.0064
Trichomonas vaginalis tubulin gamma chain, putative 0.082 0.1611 0.5957
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0041 0.0153
Toxoplasma gondii hypothetical protein 0.0037 0.0039 0.0143
Echinococcus granulosus tubulin alpha 3 chain 0.102 0.2013 0.6521
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Schistosoma mansoni alpha tubulin 0.102 0.2013 0.6521
Schistosoma mansoni hypothetical protein 0.011 0.0186 0.0602
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0018 0 0.0007
Echinococcus multilocularis hypothetical protein 0.102 0.2013 0.2013
Schistosoma mansoni integrin alpha-ps 0.0073 0.0111 0.0361
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0272 0.0882
Loa Loa (eye worm) TK/EGFR protein kinase 0.0321 0.0609 0.2252
Brugia malayi hypothetical protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0135 0.0237 0.0874
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0017 0.0064
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.005 0.0065 0.0278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0042 0.0042
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0184 0.0334 0.1438
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0032 0.0118
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0145 0.0256 0.0947
Trypanosoma brucei tubulin gamma chain 0.0821 0.1612 0.5963
Toxoplasma gondii patched family protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0023 0.0082
Loa Loa (eye worm) hypothetical protein 0.0049 0.0063 0.0232
Brugia malayi Thioredoxin reductase 0.005 0.0066 0.0244
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Leishmania major cathepsin L-like protease 0.0068 0.0101 0.0374
Mycobacterium ulcerans hypothetical protein 0.0184 0.0334 0.4989
Treponema pallidum 4'-phosphopantetheinyl transferase 0.005 0.0065 0.0965
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Schistosoma mansoni tubulin subunit beta 0.1364 0.2704 0.876
Entamoeba histolytica hypothetical protein 0.0076 0.0118 0.0435
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0066 0.0284
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0018 0 0.0002
Schistosoma mansoni hypothetical protein 0.0032 0.0029 0.0095
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0016 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0318 0.0604 0.2231
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Schistosoma mansoni tubulin subunit delta 0.0351 0.0669 0.2166
Loa Loa (eye worm) hypothetical protein 0.009 0.0145 0.0535
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0032 0.0118
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0001 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0492 0.0953 0.3525
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0018 0 0.0002
Echinococcus multilocularis insulin receptor 0.0105 0.0177 0.0177
Onchocerca volvulus 0.0037 0.0039 0.0476
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0169 0.0304 0.0304
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0051 0.0068 0.0068
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0087 0.0377
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0101 0.0374
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0001 0.0003
Onchocerca volvulus 0.0053 0.0071 0.0876
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0029 0.0095
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0066 0.0244
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0071 0.0229
Schistosoma mansoni hypothetical protein 0.0032 0.0029 0.0095
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0115 0.0195 0.0841
Echinococcus granulosus tyrosine protein kinase Btk29A 0.002 0.0005 0.0017
Plasmodium falciparum tubulin delta chain, putative 0.0351 0.0669 0.2473
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0042 0.0155
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0032 0.0117
Giardia lamblia Beta tubulin 0.1364 0.2704 1
Onchocerca volvulus 0.0184 0.0334 0.4176
Brugia malayi Steroid receptor seven-up type 2 0.0135 0.0237 0.0875
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0001 0.0003
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0017 0.0056
Echinococcus granulosus tubulin alpha chain 0.102 0.2013 0.6521
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus granulosus Tubulin beta 2C chain 0.1364 0.2704 0.876
Echinococcus granulosus Protein patched homolog 1 0.026 0.0486 0.1575
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0135 0.0237 0.0875
Trichomonas vaginalis tubulin beta chain, putative 0.102 0.2013 0.7444
Trypanosoma cruzi zeta tubulin, putative 0.0921 0.1815 0.671
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0111 0.0187 0.0187
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.025 0.0468 0.1514
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0064 0.0093 0.0093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0135 0.0237 0.0875
Trypanosoma cruzi beta tubulin, putative 0.1364 0.2704 1
Brugia malayi MH2 domain containing protein 0.0034 0.0032 0.012
Echinococcus multilocularis lamin 0.0029 0.0023 0.0023
Onchocerca volvulus 0.0031 0.0028 0.0341
Schistosoma mansoni hypothetical protein 0.0051 0.0068 0.022
Onchocerca volvulus 0.0029 0.0023 0.0274
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0405 0.0778 0.2877
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0109 0.0401
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0003 0.0011
Brugia malayi Patched protein homolog 1 0.0037 0.0039 0.0143
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0168 0.0621
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0026 0.0017 0.0017
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0051 0.0068 0.0068
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0016 0.0234
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Echinococcus multilocularis beta tubulin 0.1364 0.2704 0.2704
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0155 0.0504
Schistosoma mansoni tyrosine kinase 0.0105 0.0177 0.0572
Loa Loa (eye worm) DR-78 0.0064 0.0093 0.0343
Echinococcus multilocularis protein dispatched 1 0.0296 0.056 0.056
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0344 0.1271
Loa Loa (eye worm) hypothetical protein 0.102 0.2013 0.7444
Onchocerca volvulus 0.0025 0.0016 0.0186
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0026 0.0017 0.0064
Echinococcus granulosus retinoic acid receptor rxr beta a 0.024 0.0447 0.1448
Loa Loa (eye worm) hypothetical protein 0.0184 0.0334 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0083
Brugia malayi nuclear hormone receptor 0.0135 0.0237 0.0875
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Echinococcus multilocularis tubulin alpha chain 0.102 0.2013 0.2013
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0087 0.0323
Plasmodium vivax patched family protein, putative 0.0037 0.0039 0.0143
Mycobacterium tuberculosis Conserved protein 0.0184 0.0334 0.1438
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0104 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Loa Loa (eye worm) ctsf protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0155 0.0573
Echinococcus multilocularis integrin alpha ps 0.0035 0.0035 0.0035
Brugia malayi tubulin alpha-2 chain 0.102 0.2013 0.7444
Onchocerca volvulus 0.0029 0.0023 0.0274
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0051 0.0635
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0002 0.0007
Trichomonas vaginalis tubulin epsilon chain, putative 0.102 0.2013 0.7444
Schistosoma mansoni hypothetical protein 0.0069 0.0104 0.0337
Echinococcus multilocularis lamin dm0 0.0029 0.0023 0.0023
Brugia malayi nuclear hormone receptor family member nhr-6 0.0064 0.0093 0.0345
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0022 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0155 0.0504
Onchocerca volvulus 0.0037 0.0039 0.0476
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0016 0.0056
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0026 0.0097
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0135 0.0237 0.0767
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0018 0 0.0001
Entamoeba histolytica tubulin gamma chain 0.0821 0.1612 0.5962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0046 0.017
Mycobacterium tuberculosis Probable lipase LipD 0.0184 0.0334 0.1438
Leishmania major beta tubulin 0.1364 0.2704 1
Echinococcus multilocularis follistatin 0.004 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus multilocularis integrin alpha ps 0.0073 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0106 0.0391
Brugia malayi nuclear receptor RXR 0.0064 0.0093 0.0345
Onchocerca volvulus 0.0064 0.0093 0.116
Trichomonas vaginalis tubulin beta chain, putative 0.102 0.2013 0.7444
Onchocerca volvulus Bile acid receptor homolog 0.0135 0.0237 0.2961
Loa Loa (eye worm) hypothetical protein 0.0123 0.0212 0.0782
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0145 0.0256 0.083
Plasmodium vivax RNA helicase-1, putative 0.0026 0.0017 0.0064
Echinococcus granulosus tyrosine protein kinase Blk 0.0044 0.0053 0.0173
Trichomonas vaginalis tubulin, putative 0.0415 0.0798 0.295
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Trichomonas vaginalis tubulin epsilon chain, putative 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.026 0.0486 0.1797
Echinococcus multilocularis L aminoadipate semialdehyde 0.0176 0.0319 0.0319
Brugia malayi hypothetical protein 0.0037 0.0039 0.0143
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0003 0.0003
Schistosoma mansoni alpha tubulin 0.102 0.2013 0.6521
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0209 0.0385 0.1248
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.04
Loa Loa (eye worm) hypothetical protein 0.0605 0.118 0.4361
Leishmania major beta tubulin 0.1364 0.2704 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0077 0.0283
Brugia malayi hypothetical protein 0.0064 0.0093 0.0345
Brugia malayi Tubulin alpha chain 0.0351 0.0669 0.2473
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0016 0.0234
Brugia malayi conserved hypotetical protein 0.0064 0.0093 0.0345
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0001 0.0001
Echinococcus granulosus tubulin beta 4A class IVa 0.1364 0.2704 0.876
Echinococcus granulosus tubulin alpha 1C chain 0.102 0.2013 0.6521
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0044 0.0044
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0044 0.0162
Mycobacterium leprae cell division protein FtsZ 0.0351 0.0669 1
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Mycobacterium ulcerans esterase/lipase LipP 0.0184 0.0334 0.4989
Mycobacterium tuberculosis Probable hydrolase 0.0184 0.0334 0.1438
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0486 0.1798
Loa Loa (eye worm) hypothetical protein 0.0184 0.0334 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0061 0.0197
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0016 0.0058
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0044 0.0162
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0018 0 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.0469 0.1521
Echinococcus multilocularis tubulin beta 1 chain 0.1364 0.2704 0.2704
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0001 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0155 0.0504
Mycobacterium ulcerans hypothetical protein 0.0025 0.0016 0.0234
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0145 0.0256 0.0947
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Brugia malayi Probable isocitrate dehydrogenase 0.0018 0 0.0002
Leishmania major isocitrate dehydrogenase, putative 0.0018 0 0.0002
Brugia malayi alpha-tubulin 0.102 0.2013 0.7444
Echinococcus multilocularis tubulin alpha 3 chain 0.102 0.2013 0.2013
Echinococcus granulosus follistatin 0.004 0.0046 0.015
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0032 0.0029 0.0095
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0046 0.0171
Echinococcus granulosus Tubulin beta 2C chain 0.1364 0.2704 0.876
Trypanosoma brucei epsilon tubulin 0.082 0.1611 0.5957
Loa Loa (eye worm) glutaminase 0.0267 0.0501 0.185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0135 0.0237 0.0875
Giardia lamblia Alpha-tubulin 0.102 0.2013 0.7444
Loa Loa (eye worm) TK/ABL protein kinase 0.0232 0.0431 0.1593
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0026 0.0097
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0029 0.0109
Loa Loa (eye worm) hypothetical protein 0.0295 0.0557 0.2059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0128
Trichomonas vaginalis tubulin alpha chain, putative 0.1364 0.2704 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0155 0.0504
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0005 0.0005
Brugia malayi hypothetical protein 0.0037 0.0039 0.0143
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0104 0.0173 0.0562
Echinococcus multilocularis Smad4 0.0034 0.0032 0.0032
Trypanosoma brucei alpha tubulin 0.102 0.2013 0.7444
Onchocerca volvulus Putative organic anion transporter 0.0059 0.0084 0.1044
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0605 0.118 0.4361
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0063 0.0063
Leishmania major beta tubulin 0.1364 0.2704 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0079 0.0291
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0003 0.0013
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0095
Loa Loa (eye worm) hypothetical protein 0.004 0.0046 0.017
Giardia lamblia Alpha-tubulin 0.102 0.2013 0.7444
Leishmania major beta tubulin 0.1364 0.2704 1
Toxoplasma gondii thioredoxin reductase 0.005 0.0066 0.0244
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0047 0.0151
Echinococcus multilocularis protein patched 0.026 0.0486 0.0486
Trypanosoma brucei beta tubulin 0.1364 0.2704 1
Schistosoma mansoni patched 1 0.026 0.0486 0.1575
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Leishmania major hypothetical protein, conserved 0.0231 0.043 0.1588
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0041 0.0153
Schistosoma mansoni hypothetical protein 0.025 0.0468 0.1514
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.0359 0.0359
Brugia malayi CXXC zinc finger family protein 0.006 0.0085 0.0315
Echinococcus multilocularis musashi 0.0029 0.0023 0.0023
Loa Loa (eye worm) integrin alpha pat-2 0.025 0.0468 0.1729
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0041 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0184 0.0334 0.1438
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0106 0.0391
Giardia lamblia Delta tubulin 0.0351 0.0669 0.2473
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0003 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Brugia malayi hypothetical protein 0.0295 0.0557 0.206
Trypanosoma brucei alpha tubulin 0.102 0.2013 0.7444
Brugia malayi Nuclear hormone receptor E75 0.0064 0.0093 0.0345
Echinococcus granulosus single minded 2 0.0038 0.0042 0.0136
Loa Loa (eye worm) hypothetical protein 0.009 0.0145 0.0535
Loa Loa (eye worm) hypothetical protein 0.004 0.0046 0.017
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0061 0.0225
Trichomonas vaginalis tubulin, putative 0.0406 0.078 0.2883
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0013
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0168 0.0623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Mycobacterium tuberculosis Conserved protein 0.0184 0.0334 0.1438
Brugia malayi chromobox protein homolog 3 0.004 0.0045 0.0167
Echinococcus multilocularis epidermal growth factor receptor 0.0321 0.0609 0.0609
Plasmodium vivax delta tubulin, putative 0.0351 0.0669 0.2473
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.002 0.0005 0.0005
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0063 0.0204
Toxoplasma gondii alpha tubulin TUBA1 0.102 0.2013 0.7444
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0135 0.0237 0.0875
Brugia malayi Patched related family protein 4 0.0037 0.0039 0.0143
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0184 0.0334 0.1438
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0046 0.0171
Schistosoma mansoni integrin beta subunit 0.0196 0.0359 0.1161
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0061 0.0224
Plasmodium vivax vivapain-2 0.0018 0.0001 0.0003
Echinococcus multilocularis tubulin alpha chain 0.102 0.2013 0.2013
Brugia malayi Kelch motif family protein 0.0051 0.0067 0.0246
Trypanosoma brucei tubulin delta chain 0.0692 0.1354 0.5008
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0022 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0056
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0044 0.0161
Echinococcus multilocularis Tubulin beta 2C chain 0.1364 0.2704 0.2704
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0145 0.0256 0.0947
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0059 0.0084 0.0309
Loa Loa (eye worm) patched family protein 0.0037 0.0039 0.0142
Trichomonas vaginalis tubulin epsilon chain, putative 0.0351 0.0669 0.2473
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0003 0.0012
Brugia malayi MH2 domain containing protein 0.0034 0.0032 0.012
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0001 0.0003
Schistosoma mansoni tubulin subunit gamma 0.0821 0.1612 0.5223
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0032 0.0032
Echinococcus multilocularis tubulin alpha 1C chain 0.102 0.2013 0.2013
Toxoplasma gondii beta-1 tubulin, putative 0.1364 0.2704 1
Brugia malayi Isocitrate dehydrogenase 0.0145 0.0256 0.0947
Schistosoma mansoni tubulin subunit epsilon 0.082 0.1611 0.5218
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0176 0.0319 0.1032
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0145 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Echinococcus granulosus tm gpcr rhodopsin 0.0562 0.1093 0.354
Echinococcus granulosus Niemann Pick C1 protein 0.0865 0.1701 0.551
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.0013
Schistosoma mansoni unc-13 (munc13) 0.0018 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0001 0.0004
Mycobacterium tuberculosis Cell division protein FtsZ 0.0351 0.0669 0.2883
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0016 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0041 0.0153
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0273 0.0513 0.1895
Trypanosoma cruzi alpha tubulin, putative 0.102 0.2013 0.7444
Onchocerca volvulus 0.0059 0.0084 0.1044
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0017 0.0064
Brugia malayi ecdysone receptor 0.0064 0.0093 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0011
Echinococcus multilocularis smad 0.0034 0.0032 0.0032
Echinococcus granulosus insulin receptor 0.0105 0.0177 0.0572
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0101 0.0374
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0106 0.0391
Brugia malayi Myosin head containing protein 0.0037 0.0039 0.0143
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0051 0.0068 0.0219
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0016 0.0234
Brugia malayi nuclear receptor NHR-88 0.0135 0.0237 0.0875
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0066 0.0214
Leishmania major delta tubulin, putative 0.0692 0.1354 0.5008
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0017 0.0064
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0135 0.0237 0.0767
Loa Loa (eye worm) tubulin beta-1 chain 0.1364 0.2704 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0001 0.0003
Echinococcus multilocularis agrin 0.004 0.0046 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0093 0.0302
Echinococcus granulosus tubulin epsilon chain 0.082 0.1611 0.5218
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0056
Trypanosoma cruzi tubulin delta chain 0.0692 0.1354 0.5008
Echinococcus granulosus tubulin delta chain 0.0351 0.0669 0.2166
Loa Loa (eye worm) BEN-1 protein 0.1364 0.2704 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0013
Echinococcus multilocularis Dipeptidyl peptidase 9 0.007 0.0106 0.0106
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0029 0.0029
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0087 0.0323
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.007 0.0106 0.0393
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0056
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0003 0.001
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus multilocularis cysteine protease 0.0018 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0042 0.0135
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0017 0.0064
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0101 0.0374
Plasmodium falciparum thioredoxin reductase 0.005 0.0066 0.0244
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0032 0.0032
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0018 0 0.0001
Echinococcus granulosus cathepsin l1 0.0018 0.0001 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0135 0.0237 0.0767
Echinococcus granulosus lamin 0.0029 0.0023 0.0073
Schistosoma mansoni nuclear hormone receptor 0.0135 0.0237 0.0767
Mycobacterium leprae Probable lipase LipE 0.0184 0.0334 0.4989
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Plasmodium falciparum alpha tubulin 2 0.102 0.2013 0.7444
Trichomonas vaginalis tubulin gamma chain, putative 0.0351 0.0669 0.2473
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0051 0.019
Schistosoma mansoni lamin 0.0029 0.0023 0.0073
Loa Loa (eye worm) tubulin gamma chain 0.0821 0.1612 0.5962
Echinococcus granulosus geminin 0.1555 0.3087 1
Onchocerca volvulus 0.0059 0.0084 0.1044
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0044 0.0142
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0016 0.0068
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0023 0.0082
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0018 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0029 0.0109
Echinococcus multilocularis Niemann Pick C1 protein 0.0865 0.1701 0.1701
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0022 0.0081
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus granulosus tubulin alpha chain 0.102 0.2013 0.6521
Echinococcus granulosus lamin dm0 0.0029 0.0023 0.0073
Leishmania major hypothetical protein, conserved 0.0184 0.0334 0.1234
Echinococcus granulosus c src tyrosine kinase 0.002 0.0005 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0016 0.0234
Loa Loa (eye worm) TK protein kinase 0.0044 0.0053 0.0196
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0106 0.0391
Echinococcus granulosus beta tubulin 0.1364 0.2704 0.876
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0155 0.0155
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0016 0.0058
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0053 0.0196
Echinococcus granulosus fibroblast growth factor receptor 4 0.0111 0.0187 0.0606
Echinococcus multilocularis Tubulin alpha 1 chain 0.102 0.2013 0.2013
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0046 0.0171
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Trichomonas vaginalis tubulin beta chain, putative 0.102 0.2013 0.7444
Brugia malayi hypothetical protein 0.0173 0.0313 0.1158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0007
Echinococcus multilocularis Tubulin beta 2C chain 0.1364 0.2704 0.2704
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0085 0.0314
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Loa Loa (eye worm) hypothetical protein 0.0128 0.0221 0.0816
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.0469 0.0469
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0135 0.0237 0.0875
Trichomonas vaginalis tubulin beta chain, putative 0.102 0.2013 0.7444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Loa Loa (eye worm) hypothetical protein 0.0184 0.0334 0.1232
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0135 0.0237 0.0874
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0026 0.0017 0.0017
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0044 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Brugia malayi hypothetical protein 0.0071 0.0109 0.0401
Schistosoma mansoni tyrosine kinase 0.002 0.0005 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0027 0.0101
Schistosoma mansoni nuclear receptor 0.0064 0.0093 0.0302
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0109 0.0401
Echinococcus multilocularis ecdysone induced protein 78C 0.0135 0.0237 0.0237
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0064 0.0093 0.0302
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Brugia malayi PAS domain containing protein 0.0052 0.0069 0.0254
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0029 0.0095
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0003 0.044
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0071 0.0109 0.0352
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.022 0.0713
Trichomonas vaginalis tubulin gamma chain, putative 0.0821 0.1612 0.5963
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0016 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0026 0.0026
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0041 0.0153
Schistosoma mansoni tubulin subunit beta 0.1364 0.2704 0.876
Schistosoma mansoni DNA helicase recq1 0.003 0.0026 0.0085
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0145 0.0256 0.083
Brugia malayi tailless protein 0.0064 0.0093 0.0345
Echinococcus multilocularis 0.0098 0.0162 0.0162
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0032 0.0105
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0605 0.118 0.4365
Plasmodium vivax tubulin gamma chain, putative 0.0821 0.1612 0.5963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0041 0.0153
Giardia lamblia GTOR 0.0048 0.0061 0.0225
Onchocerca volvulus 0.0037 0.0039 0.0476
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0001 0.0001
Echinococcus multilocularis tubulin subunit TubB 0.102 0.2013 0.2013
Echinococcus granulosus tubulin gamma 1 chain 0.0821 0.1612 0.5223
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0032 0.0116
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0055 0.0205
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0155 0.0575
Brugia malayi Niemann-Pick C1 protein precursor 0.0605 0.118 0.4362
Schistosoma mansoni tyrosine kinase 0.002 0.0005 0.0017
Brugia malayi Integrin beta pat-3 precursor 0.0333 0.0633 0.2341
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0063 0.0204
Plasmodium falciparum glutathione reductase 0.005 0.0066 0.0244
Brugia malayi sodium-independent organic anion transporter family protein 0.0059 0.0084 0.0311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0135 0.0237 0.0874
Brugia malayi Tubulin alpha chain 0.102 0.2013 0.7444
Trypanosoma brucei alpha tubulin 0.102 0.2013 0.7444
Brugia malayi ecdysteroid receptor 0.0135 0.0237 0.0875
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0184 0.0334 0.1232
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0061 0.0225
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0046 0.0171
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0135 0.0237 0.2961
Mycobacterium ulcerans cell division protein FtsZ 0.0351 0.0669 1
Loa Loa (eye worm) tubulin beta-4 chain 0.1364 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0082
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0044 0.0162
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0018 0 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0562 0.1093 0.1093
Echinococcus multilocularis neuropeptide s receptor 0.0501 0.097 0.097
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0077 0.0248
Loa Loa (eye worm) hypothetical protein 0.067 0.1309 0.4841
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0061 0.0061
Echinococcus granulosus tyrosine protein kinase ABL1 0.0232 0.0431 0.1397
Leishmania major cathepsin L-like protease 0.0018 0.0001 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0065 0.0238
Entamoeba histolytica hypothetical protein 0.0076 0.0118 0.0435
Schistosoma mansoni steroid hormone receptor ad4bp 0.0135 0.0237 0.0767
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0351 0.0669 0.2473
Echinococcus granulosus tubulin alpha 1C chain 0.102 0.2013 0.6521
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.0324 0.4059
Schistosoma mansoni nuclear receptor 0.0064 0.0093 0.0302
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0108 0.0183 0.0183
Echinococcus granulosus Tubulin beta 2C chain 0.1364 0.2704 0.876
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0048 0.0177
Brugia malayi secreted modular calcium-binding protein 1 0.004 0.0046 0.0171
Echinococcus multilocularis Niemann Pick C1 protein 0.0605 0.118 0.118
Loa Loa (eye worm) hypothetical protein 0.0051 0.0067 0.0245
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0102
Trichomonas vaginalis penicillin-binding protein, putative 0.0184 0.0334 0.1234
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0005 0.0017
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0118 0.0118
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0013
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.005 0.0065 0.0965
Loa Loa (eye worm) hypoxia-induced factor 1 0.016 0.0286 0.1057
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0048 0.0176
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0046 0.0171
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.007 0.0106 0.0344
Brugia malayi hypothetical protein 0.0059 0.0084 0.0311
Trypanosoma cruzi hypothetical protein, conserved 0.0184 0.0334 0.1234
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0001 0.0001
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Echinococcus multilocularis tubulin epsilon chain 0.082 0.1611 0.1611
Echinococcus multilocularis tubulin alpha chain 0.102 0.2013 0.2013
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0003 0.0012
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0135 0.0237 0.0767
Toxoplasma gondii isocitrate dehydrogenase 0.0145 0.0256 0.0947
Leishmania major alpha tubulin 0.102 0.2013 0.7444
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0209 0.0385 0.4823
Brugia malayi prolyl oligopeptidase family protein 0.007 0.0106 0.0393
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0002 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0173 0.0313 0.1157
Echinococcus multilocularis isocitrate dehydrogenase 0.0145 0.0256 0.0256
Loa Loa (eye worm) tubulin alpha-3 chain 0.0605 0.118 0.4364
Brugia malayi sulfakinin receptor protein 0.0237 0.0442 0.1633
Loa Loa (eye worm) hypothetical protein 0.0064 0.0093 0.0343
Echinococcus multilocularis Tubulin beta 2C chain 0.1364 0.2704 0.2704
Entamoeba histolytica hypothetical protein 0.0076 0.0118 0.0435
Echinococcus granulosus Tubulin alpha 1 chain 0.102 0.2013 0.6521
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0048 0.0177
Loa Loa (eye worm) transcription factor SMAD2 0.0492 0.0953 0.3525
Brugia malayi nuclear receptor NHR-67 0.0064 0.0093 0.0345
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0068 0.0219
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0046 0.0171
Loa Loa (eye worm) agrin synaptic family protein 0.004 0.0046 0.017
Echinococcus granulosus tubulin beta 1 chain 0.1364 0.2704 0.876
Leishmania major phosphopantetheinyl transferase-like protein 0.005 0.0065 0.0238
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0135 0.0237 0.0237
Schistosoma mansoni organic anion transporter 0.0059 0.0084 0.0272
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Schistosoma mansoni tubulin subunit beta 0.1364 0.2704 0.876
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0055 0.0205
Trichomonas vaginalis tubulin epsilon chain, putative 0.102 0.2013 0.7444
Echinococcus granulosus Smad4 0.0034 0.0032 0.0105
Schistosoma mansoni retinoic acid receptor RXR 0.024 0.0447 0.1448
Loa Loa (eye worm) cysteine protease 0.0018 0.0001 0.0001
Loa Loa (eye worm) Smad1 0.0034 0.0032 0.0118
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0029 0.0107
Brugia malayi MH1 domain containing protein 0.0034 0.0032 0.012
Brugia malayi Heterochromatin protein 1 0.0071 0.0108 0.04
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Trypanosoma cruzi MFS transporter, putative 0.0059 0.0084 0.0311
Brugia malayi nuclear receptor NHR-88 0.0064 0.0093 0.0345
Leishmania major cathepsin L-like protease 0.0018 0.0001 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0135 0.0237 0.0767
Plasmodium vivax ataxin-2 like protein, putative 0.0231 0.043 0.1588
Schistosoma mansoni tyrosine kinase 0.0168 0.0303 0.0983
Trypanosoma brucei PAB1-binding protein , putative 0.0231 0.043 0.1588
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0016 0.0234
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0022 0.001 0.0032
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0003 0.001
Entamoeba histolytica tubulin family protein 0.1364 0.2704 1
Echinococcus granulosus agrin 0.004 0.0046 0.015
Loa Loa (eye worm) nuclear factor I 0.0019 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0082
Loa Loa (eye worm) tubulin alpha chain 0.102 0.2013 0.7444
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0057
Echinococcus multilocularis beta LACTamase domain containing family member 0.0184 0.0334 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Echinococcus granulosus Immunoglobulin 0.0022 0.001 0.0032
Echinococcus granulosus thyroid hormone receptor alpha 0.0064 0.0093 0.0302
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0145 0.0256 0.0947
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0032 0.0117
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0135 0.0237 0.0767
Schistosoma mansoni tyrosine kinase 0.0051 0.0068 0.0219
Echinococcus multilocularis cysteine protease 0.0018 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0145 0.0256 0.0947
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Echinococcus granulosus tubulin subunit beta 0.1364 0.2704 0.876
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.005 0.0065 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0101 0.0374
Brugia malayi CHE-14 protein 0.026 0.0486 0.1798
Echinococcus granulosus alpha tubulin 0.102 0.2013 0.6521
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0087 0.0087
Onchocerca volvulus 0.0037 0.0039 0.0476
Onchocerca volvulus 0.0184 0.0334 0.4176
Loa Loa (eye worm) alpha-tubulin isotype 2 0.067 0.1309 0.4841
Echinococcus multilocularis tubulin alpha 1C chain 0.102 0.2013 0.2013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0135
Schistosoma mansoni nephrin 0.0028 0.0022 0.0072
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0134 0.0234 0.0757
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0046 0.0171
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0071 0.0109 0.0352
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Echinococcus granulosus beta LACTamase domain containing family member 0.0184 0.0334 0.1081
Plasmodium vivax tubulin alpha chain, putative 0.102 0.2013 0.7444
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0018 0 0.0007
Echinococcus multilocularis integrin alpha 3 0.0125 0.0215 0.0215
Brugia malayi Tubulin beta chain 0.0351 0.0669 0.2473
Trichomonas vaginalis D-aminoacylase, putative 0.0184 0.0334 0.1234
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0003 0.0052
Schistosoma mansoni cpg binding protein 0.0063 0.0092 0.0299
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.0093 0.116
Schistosoma mansoni tyrosine kinase 0.0174 0.0315 0.1021
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0034
Leishmania major cathepsin L-like protease 0.0068 0.0101 0.0374
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0118 0.0383
Loa Loa (eye worm) patched family protein 0.0037 0.0039 0.0142
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0034
Plasmodium vivax tubulin alpha chain, putative 0.102 0.2013 0.7444
Trypanosoma brucei beta tubulin 0.1364 0.2704 1
Schistosoma mansoni tubulin subunit beta 0.1364 0.2704 0.876
Onchocerca volvulus 0.0135 0.0237 0.2961
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.007 0.0106 0.0393
Brugia malayi hypothetical protein 0.0059 0.0084 0.0311
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0063 0.0204
Brugia malayi Immunoglobulin I-set domain containing protein 0.0114 0.0193 0.0715
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.0359 0.1163
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.0013
Brugia malayi protein C24B5.3 0.0037 0.0039 0.0143
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0273 0.0513 0.1894
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0135 0.0237 0.0874
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Echinococcus granulosus integrin alpha ps 0.0073 0.0111 0.0361
Onchocerca volvulus 0.0064 0.0093 0.116
Giardia lamblia Gamma tubulin 0.0821 0.1612 0.5963
Brugia malayi steroid hormone receptor 0.0135 0.0237 0.0875
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0324 0.1199
Loa Loa (eye worm) hypothetical protein 0.0053 0.0071 0.0259
Brugia malayi Cathepsin L-like precursor 0.0018 0.0001 0.0003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0003 0.0013
Brugia malayi Integrin alpha pat-2 precursor 0.0162 0.0291 0.1077
Brugia malayi nuclear hormone receptor family member odr-7 0.0064 0.0093 0.0345
Onchocerca volvulus 0.0059 0.0084 0.1044
Leishmania major trypanothione reductase 0.005 0.0066 0.0244
Schistosoma mansoni tyrosine kinase 0.0051 0.0068 0.0219
Loa Loa (eye worm) tubulin beta chain 0.1364 0.2704 1
Giardia lamblia Epsilon tubulin 0.0405 0.0778 0.2877
Echinococcus granulosus tyrosine protein kinase HCK 0.0037 0.0039 0.0126
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0001 0.0001
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0145 0.0256 0.0947
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0111 0.0187 0.0606
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0184 0.0334 0.1081
Schistosoma mansoni tyrosine kinase 0.0168 0.0303 0.0983
Schistosoma mansoni hypothetical protein 0.0853 0.1678 0.5435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0017 0.0062
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0016 0.0058
Trichomonas vaginalis tubulin gamma chain, putative 0.1364 0.2704 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0145 0.0256 0.0256
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0051 0.0068 0.0219
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Toxoplasma gondii patched family protein 0.0037 0.0039 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0135 0.0237 0.0875
Loa Loa (eye worm) beta-tubulin 0.1364 0.2704 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0115 0.0195 0.2918
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0415 0.0798 0.295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0022 0.0081
Onchocerca volvulus 0.0051 0.0068 0.0843
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0026 0.0017 0.0074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0000045726 0.0001
Entamoeba histolytica hypothetical protein 0.005 0.0065 0.0237
Schistosoma mansoni tubulin subunit alpha 0.102 0.2013 0.6521
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.026 0.0486 0.1797
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0309
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0093 0.0302
Echinococcus granulosus tubulin alpha chain 0.102 0.2013 0.6521
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0068 0.0251
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0063 0.0232
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0055 0.0205
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0053 0.0053
Leishmania major beta tubulin 0.1364 0.2704 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0115 0.0195 0.0841
Leishmania major cathepsin L-like protease 0.0018 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0101 0.0168 0.0621
Trichomonas vaginalis tubulin alpha chain, putative 0.0415 0.0798 0.295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0135 0.0237 0.0874
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0016 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0016 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0135 0.0237 0.0875
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0221 0.0952
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Loa Loa (eye worm) steroid hormone receptor 0.0135 0.0237 0.0874
Mycobacterium leprae conserved hypothetical protein 0.005 0.0065 0.0965
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0001 0.0003
Echinococcus granulosus Tubulin beta 2C chain 0.1364 0.2704 0.876
Mycobacterium ulcerans glutaminase 0.0267 0.0501 0.7486
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0115 0.0195 0.0841
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0614 0.1198 0.3882
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0142
Brugia malayi Tyrosine-protein kinase abl-1 0.0135 0.0237 0.0876
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0106 0.0343
Onchocerca volvulus 0.0037 0.0039 0.0476
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.0513 0.1895
Schistosoma mansoni integrin alpha 0.0162 0.0291 0.0943
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0044 0.0163
Brugia malayi SRC-1 0.0051 0.0068 0.025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0001 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0184 0.0334 0.1081
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0059 0.0084 0.0084
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0026 0.0095
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0135 0.0237 0.0767
Loa Loa (eye worm) RecQ helicase 0.0044 0.0053 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0001 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0145 0.0256 0.0947
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0001 0.0001
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0026 0.0097
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0145 0.0256 0.0947
Plasmodium vivax tubulin epsilon chain, putative 0.082 0.1611 0.5957
Brugia malayi Patched family protein 0.0037 0.0039 0.0143
Schistosoma mansoni Smad4 0.0034 0.0032 0.0105
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0044 0.0162
Onchocerca volvulus Protein patched homolog 0.0037 0.0039 0.0476
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0003 0.0013

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1995 nM Inhibition of DPP4 ChEMBL. 17337342
IC50 (binding) = 1995 nM Inhibition of DPP4 ChEMBL. 17337342

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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