Detailed information for compound 457705

Basic information

Technical information
  • TDR Targets ID: 457705
  • Name: (3E)-1-(4-butan-2-ylphenyl)-3-(2-chloroethylc arbamoylimino)urea
  • MW: 310.779 | Formula: C14H19ClN4O2
  • H donors: 2 H acceptors: 2 LogP: 3.62 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClCCNC(=O)/N=N/C(=O)Nc1ccc(cc1)C(CC)C
  • InChi: 1S/C14H19ClN4O2/c1-3-10(2)11-4-6-12(7-5-11)17-14(21)19-18-13(20)16-9-8-15/h4-7,10H,3,8-9H2,1-2H3,(H,16,20)(H,17,21)/b19-18+
  • InChiKey: VBFJSZBGMMVWPV-VHEBQXMUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3E)-1-(2-chloroethyl)-3-[(4-sec-butylphenyl)carbamoylimino]urea
  • (3E)-1-(2-chloroethyl)-3-[oxo-(4-sec-butylanilino)methyl]iminourea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Schistosoma mansoni smad1 5 8 and 0.0024 0.0065 0.0092
Schistosoma mansoni tyrosine kinase 0.025 0.1497 0.2281
Schistosoma mansoni DNA helicase recq1 0.0028 0.0093 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0008 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0106 0.0582 0.0878
Onchocerca volvulus 0.0047 0.021 0.1
Plasmodium vivax tubulin epsilon chain, putative 0.0608 0.3765 0.5749
Trypanosoma brucei beta tubulin 0.1047 0.6548 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0047 0.021 0.0314
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Leishmania major epsilon tubulin, putative 0.0608 0.3765 0.5745
Plasmodium falciparum tubulin beta chain 0.1047 0.6548 1
Echinococcus granulosus lamin dm0 0.0027 0.0082 0.0113
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0047 0.021 0.0309
Echinococcus multilocularis Tubulin beta 2C chain 0.1047 0.6548 0.6545
Brugia malayi glutathione reductase 0.0047 0.0209 0.0313
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0136 0.0128
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0165 0.0957 0.1456
Echinococcus multilocularis peroxisome assembly protein 26 0.0782 0.487 0.4866
Schistosoma mansoni nuclear receptor nhr-48 0.0047 0.021 0.0313
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0062 0.0092
Schistosoma mansoni hypothetical protein 0.0032 0.0119 0.0174
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0106 0.0582 0.1358
Schistosoma mansoni single-minded 0.0048 0.0217 0.0325
Leishmania major beta tubulin 0.1047 0.6548 1
Schistosoma mansoni hypothetical protein 0.0849 0.5293 0.8082
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Leishmania major beta tubulin 0.1047 0.6548 1
Schistosoma mansoni nephrin 0.0026 0.0081 0.0116
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0178 0.017
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0582 0.0882
Schistosoma mansoni apoferritin-2 0.0018 0.0026 0.0032
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0067 0.0094
Echinococcus multilocularis tubulin alpha chain 0.0782 0.487 0.4866
Leishmania major beta tubulin 0.1047 0.6548 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0016 0.0017
Echinococcus multilocularis neuropeptide s receptor 0.0467 0.287 0.2864
Onchocerca volvulus 0.0255 0.1529 0.7889
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0145 0.0197
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0196 0.1156 0.1756
Brugia malayi Tubulin alpha-2 chain 0.0782 0.487 0.7435
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0082 0.0119
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0047 0.0059
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0152 0.0225
Schistosoma mansoni patched 1 0.0171 0.0994 0.1512
Loa Loa (eye worm) TK protein kinase 0.0035 0.0136 0.0202
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0305 0.0297
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0582 0.0882
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0699 0.1057
Schistosoma mansoni tubulin subunit beta 0.1047 0.6548 1
Echinococcus multilocularis lamin dm0 0.0027 0.0082 0.0074
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0026 0.0023
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0209 0.0317
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0138 0.0199
Schistosoma mansoni tyrosine kinase 0.015 0.0865 0.1315
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.002 0.0038 0.003
Onchocerca volvulus 0.006 0.0294 0.1438
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Echinococcus granulosus tyrosine protein kinase Lyn 0.0049 0.0223 0.0328
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0964 0.4941
Schistosoma mansoni smad1 5 8 and 0.0024 0.0065 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0062 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0152 0.0225
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0662 0.4093
Schistosoma mansoni tyrosine kinase 0.002 0.0038 0.005
Echinococcus granulosus roundabout 2 0.0029 0.01 0.0141
Loa Loa (eye worm) patched family protein 0.0024 0.0067 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Loa Loa (eye worm) patched family protein 0.0024 0.0067 0.0096
Mycobacterium ulcerans lipase LipD 0.0106 0.0582 0.362
Onchocerca volvulus 0.0055 0.0262 0.1272
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0178 0.026
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0047 0.021 0.0313
Schistosoma mansoni cell adhesion molecule 0.0026 0.0081 0.0117
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Mycobacterium ulcerans esterase/lipase LipP 0.0106 0.0582 0.362
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0294 0.0443
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0077 0.0109
Brugia malayi ecdysteroid receptor 0.0099 0.0541 0.0821
Echinococcus multilocularis integrin alpha ps 0.0068 0.0342 0.0334
Loa Loa (eye worm) hypothetical protein 0.0099 0.0538 0.0816
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0122 0.018
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0018 0.0016
Loa Loa (eye worm) tubulin beta chain 0.0263 0.158 0.2409
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0062 0.0082
Echinococcus multilocularis tubulin alpha 0.0582 0.3599 0.3594
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0245 0.0367
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trypanosoma brucei tubulin delta chain 0.0427 0.2621 0.3996
Brugia malayi SPARC precursor 0.0038 0.0152 0.0225
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1515 0.2314
Schistosoma mansoni alpha tubulin 0.0782 0.487 0.7435
Leishmania major cathepsin L-like protease 0.0063 0.0312 0.0465
Echinococcus multilocularis tubulin alpha 3 chain 0.0782 0.487 0.4866
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Brugia malayi hypothetical protein 0.0071 0.0361 0.0546
Echinococcus multilocularis musashi 0.0027 0.0082 0.0074
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0109 0.0164
Loa Loa (eye worm) steroid hormone receptor 0.0099 0.0541 0.0821
Echinococcus granulosus Tubulin alpha 1 chain 0.0782 0.487 0.7434
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0198 0.019
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.027 0.04
Echinococcus multilocularis roundabout 2 0.0029 0.01 0.0092
Schistosoma mansoni hypothetical protein 0.0159 0.092 0.1399
Trypanosoma cruzi epsilon tubulin, putative 0.0608 0.3765 0.5747
Mycobacterium tuberculosis Conserved protein 0.0106 0.0582 0.1358
Echinococcus granulosus Smad4 0.0024 0.0065 0.0087
Mycobacterium ulcerans cell division protein FtsZ 0.0263 0.158 1
Loa Loa (eye worm) TK protein kinase 0.0106 0.0588 0.0892
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0119
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0099 0.0541 0.0821
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0062 0.0082
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0215 0.0322
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0106 0.0582 0.1358
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0262 0.0394
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus multilocularis lamin 0.0027 0.0082 0.0074
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0178 0.017
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0194 0.0289
Brugia malayi Nuclear hormone receptor E75 0.0047 0.021 0.0314
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0194 0.0285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.0099
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0255 0.1529 0.233
Plasmodium vivax vivapain-2 0.0016 0.0018 0.0026
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0093 0.0129
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0062
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0194 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Echinococcus granulosus tubulin subunit beta 0.1047 0.6548 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0064 0.0085
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0398 0.2431 0.3709
Mycobacterium tuberculosis Cell division protein FtsZ 0.0263 0.158 0.3753
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0587 0.1369
Echinococcus multilocularis integrin alpha 3 0.0115 0.0645 0.0638
Entamoeba histolytica cysteine protease, putative 0.0016 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0114 0.0636 0.0965
Toxoplasma gondii patched family protein 0.0024 0.0067 0.0094
Trypanosoma cruzi alpha tubulin, putative 0.0782 0.487 0.7435
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0067 0.0099
Brugia malayi hypothetical protein 0.0161 0.0932 0.1418
Echinococcus multilocularis epidermal growth factor receptor 0.025 0.1497 0.149
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.003 0.0039
Brugia malayi hypothetical protein 0.0023 0.0063 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Plasmodium vivax hypothetical protein, conserved 0.0106 0.0582 0.0887
Loa Loa (eye worm) TK/EGFR protein kinase 0.0462 0.284 0.4334
Plasmodium falciparum glutathione reductase 0.0047 0.0209 0.0295
Toxoplasma gondii patched family protein 0.0024 0.0067 0.0094
Echinococcus granulosus tyrosine protein kinase Fyn 0.0048 0.022 0.0324
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0178 0.026
Echinococcus multilocularis dnaJ subfamily B 0.0854 0.5322 0.5318
Brugia malayi Tyrosine-protein kinase abl-1 0.0097 0.053 0.0803
Echinococcus granulosus epidermal growth factor receptor 0.025 0.1497 0.2277
Trypanosoma brucei PAB1-binding protein , putative 0.0099 0.0538 0.0811
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0082 0.0119
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0289 0.1746 0.2661
Schistosoma mansoni hypothetical protein 0.0164 0.0955 0.1453
Schistosoma mansoni tubulin subunit alpha 0.0782 0.487 0.7435
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) beta-lactamase 0.0106 0.0582 0.0884
Echinococcus multilocularis Tubulin beta 2C chain 0.1047 0.6548 0.6545
Loa Loa (eye worm) tubulin alpha chain 0.0782 0.487 0.7435
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0171 0.0994 0.1513
Loa Loa (eye worm) hypothetical protein 0.0084 0.0446 0.0676
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0062 0.0092
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.01
Schistosoma mansoni integrin alpha 0.0151 0.0868 0.1319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0145 0.0221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Loa Loa (eye worm) tubulin alpha chain 0.0782 0.487 0.7435
Echinococcus multilocularis cysteine protease 0.0016 0.0018 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Schistosoma mansoni alpha tubulin 0.0782 0.487 0.7435
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus multilocularis ecdysone induced protein 78C 0.0099 0.0541 0.0534
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0018 0.0005
Brugia malayi hypoxia-induced factor 1 0.0148 0.0853 0.1298
Schistosoma mansoni lamin 0.0027 0.0082 0.0118
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0038 0.005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0787 0.1192
Entamoeba histolytica hypothetical protein 0.0072 0.0368 0.056
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.0812 0.1234
Plasmodium falciparum tubulin epsilon chain, putative 0.0608 0.3765 0.574
Echinococcus granulosus alpha tubulin 0.0782 0.487 0.7434
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0209 0.0307
Echinococcus multilocularis insulin receptor 0.015 0.0865 0.0858
Echinococcus multilocularis Tubulin beta 2C chain 0.1047 0.6548 0.6545
Trichomonas vaginalis tubulin beta chain, putative 0.0782 0.487 0.7437
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0368 0.2203
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.0541 0.0821
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0994 0.1519
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0122 0.018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0017
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0099 0.0541 0.082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trichomonas vaginalis tubulin, putative 0.0319 0.1933 0.2952
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0198 0.0294
Mycobacterium tuberculosis Conserved protein 0.0106 0.0582 0.1358
Brugia malayi beta-tubulin, identical 0.1047 0.6548 1
Brugia malayi Tubulin alpha chain 0.0263 0.158 0.2409
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0072 0.0368 0.225
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0047 0.021 0.0202
Schistosoma mansoni ferritin 0.0018 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Echinococcus multilocularis tubulin beta 1 chain 0.1047 0.6548 0.6545
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0248 0.0372
Loa Loa (eye worm) hypothetical protein 0.0106 0.0582 0.0884
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1021 0.1559
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0048 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0052 0.0245 0.0369
Brugia malayi Thioredoxin reductase 0.0047 0.0209 0.0313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Plasmodium vivax tubulin gamma chain, putative 0.0608 0.3768 0.5753
Loa Loa (eye worm) hypothetical protein 0.0038 0.0152 0.0225
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0245 0.0369
Leishmania major beta tubulin 0.1047 0.6548 1
Echinococcus granulosus GPCR family 2 0.0033 0.0122 0.0174
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0262 0.0393
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0018 0.0026
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0093 0.0117
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0171 0.0261
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0093 0.0135
Plasmodium vivax tubulin alpha chain, putative 0.0782 0.487 0.7436
Schistosoma mansoni ferritin 0.0018 0.0026 0.0032
Schistosoma mansoni tyrosine kinase 0.0103 0.0569 0.0862
Trypanosoma brucei protein kinase, putative 0.0056 0.027 0.04
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0109 0.0154
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.021 0.0202
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0305 0.0459
Echinococcus granulosus lamin 0.0027 0.0082 0.0113
Trichomonas vaginalis tubulin epsilon chain, putative 0.1047 0.6548 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0178 0.026
Echinococcus granulosus insulin receptor 0.015 0.0865 0.1311
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0263 0.158 0.2413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0137 0.0209
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0018 0.0022
Brugia malayi hypothetical protein 0.0047 0.0211 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.0541 0.0821
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Trypanosoma brucei zeta tubulin, putative 0.0538 0.3321 0.5066
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0152 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0018 0.0028
Brugia malayi MH1 domain containing protein 0.0024 0.0065 0.0093
Echinococcus granulosus Niemann Pick C1 protein 0.0398 0.2431 0.3706
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1515 0.2314
Onchocerca volvulus Protein patched homolog 0.0024 0.0067 0.0252
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0326 0.049
Brugia malayi Patched related family protein 12 0.0024 0.0067 0.0096
Trichomonas vaginalis tubulin gamma chain, putative 0.0608 0.3765 0.575
Schistosoma mansoni cpg binding protein 0.0063 0.0315 0.0474
Echinococcus granulosus muscleblind protein 0.0165 0.0957 0.1451
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0099 0.0541 0.0821
Onchocerca volvulus Protein ultraspiracle homolog 0.0099 0.0541 0.2731
Leishmania major beta tubulin 0.1047 0.6548 1
Echinococcus granulosus single minded 2 0.0035 0.0139 0.02
Schistosoma mansoni thyroid hormone receptor 0.0223 0.1327 0.202
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0587 0.361
Schistosoma mansoni nuclear receptor 0.0047 0.021 0.0313
Brugia malayi ecdysone receptor 0.0047 0.021 0.0314
Loa Loa (eye worm) hypothetical protein 0.0519 0.3203 0.4889
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0155 0.0212
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0152 0.0225
Loa Loa (eye worm) tubulin alpha-3 chain 0.0464 0.2851 0.435
Brugia malayi hypothetical protein 0.0024 0.0067 0.0096
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0024 0.0035
Echinococcus granulosus cathepsin l1 0.0016 0.0018 0.0016
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0145 0.0209
Schistosoma mansoni tubulin subunit beta 0.1047 0.6548 1
Brugia malayi hypothetical protein 0.0052 0.0245 0.0369
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0145 0.0221
Plasmodium vivax tubulin beta chain, putative 0.1047 0.6548 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Echinococcus multilocularis geminin 0.0849 0.5293 0.5289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0096 0.0147
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0024 0.0013
Brugia malayi Tyrosine-protein kinase abl-1 0.0126 0.0709 0.1077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.027 0.04
Leishmania major beta tubulin 0.1047 0.6548 1
Onchocerca volvulus 0.0024 0.0067 0.0252
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0262 0.1272
Echinococcus multilocularis Immunoglobulin 0.0021 0.0045 0.0037
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0062 0.0233
Loa Loa (eye worm) DR-78 0.0047 0.021 0.0314
Echinococcus granulosus bloom syndrome protein 0.0041 0.0171 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0263 0.158 0.2413
Trypanosoma brucei beta tubulin 0.1047 0.6548 1
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0582 0.0889
Loa Loa (eye worm) hypothetical protein 0.0104 0.0571 0.0866
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0194 0.0295
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0062 0.0305 0.0297
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus multilocularis tubulin gamma 1 chain 0.0608 0.3768 0.3763
Trichomonas vaginalis tubulin alpha chain, putative 0.1047 0.6548 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0319 0.1933 0.2952
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0427 0.2621 0.3999
Loa Loa (eye worm) hypothetical protein 0.0052 0.0245 0.0369
Echinococcus multilocularis protein dispatched 1 0.0195 0.1147 0.114
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0209 0.0463
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0361 0.0545
Echinococcus multilocularis tubulin alpha 1C chain 0.0782 0.487 0.4866
Echinococcus granulosus FTZ F1 alpha 0.0099 0.0541 0.0815
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0171 0.0261
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0016 0.0017
Echinococcus granulosus peroxisome assembly protein 26 0.0782 0.487 0.7434
Echinococcus multilocularis isocitrate dehydrogenase 0.0062 0.0305 0.0297
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0048 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus multilocularis Niemann Pick C1 protein 0.0568 0.3512 0.3507
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Brugia malayi hypothetical protein 0.0052 0.0245 0.0369
Loa Loa (eye worm) hypothetical protein 0.0038 0.0152 0.0225
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0277 0.0416
Loa Loa (eye worm) tubulin gamma chain 0.0608 0.3768 0.5751
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0062 0.0305 0.0464
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0099 0.0541 0.082
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0062 0.0292
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0655 0.0994
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0062 0.0305 0.0693
Trypanosoma cruzi tubulin gamma chain 0.0608 0.3768 0.5751
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0106 0.0582 0.362
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0227 0.0339
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0699 0.0692
Treponema pallidum cell division protein FtsZ 0.0263 0.158 1
Echinococcus granulosus tubulin alpha 1C chain 0.0782 0.487 0.7434
Trichomonas vaginalis conserved hypothetical protein 0.0263 0.158 0.2413
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.027 0.0412
Brugia malayi Kelch motif family protein 0.0047 0.0211 0.0316
Brugia malayi Steroid receptor seven-up type 2 0.0099 0.0541 0.0821
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Echinococcus granulosus tyrosine protein kinase Btk29A 0.002 0.0038 0.0045
Leishmania major delta tubulin, putative 0.0427 0.2621 0.3996
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1515 0.2314
Schistosoma mansoni tyrosine kinase 0.002 0.0038 0.005
Schistosoma mansoni hypothetical protein 0.0071 0.0363 0.0547
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0099 0.0541 0.082
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0152 0.0224
Entamoeba histolytica hypothetical protein 0.0071 0.0361 0.055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.027 0.0405
Mycobacterium tuberculosis Probable lipase LipE 0.0106 0.0582 0.1358
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0031 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0008 0.0012
Echinococcus granulosus tubulin beta 4A class IVa 0.1047 0.6548 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0194 0.0291
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0103 0.0569 0.0858
Schistosoma mansoni tyrosine kinase 0.025 0.1497 0.2281
Leishmania major beta tubulin 0.1047 0.6548 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0194 0.0295
Echinococcus multilocularis follistatin 0.0038 0.0152 0.0144
Echinococcus granulosus defective proboscis extension response 0.0021 0.0045 0.0056
Brugia malayi nuclear hormone receptor family member odr-7 0.0047 0.021 0.0314
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0099 0.0541 0.0534
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.027 0.0405
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0152 0.0225
Echinococcus granulosus Tubulin beta 2C chain 0.1047 0.6548 1
Loa Loa (eye worm) tubulin alpha 2 0.0519 0.3203 0.4889
Leishmania major cytochrome p450-like protein 0.0026 0.0077 0.0105
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0262 0.1272
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Brugia malayi tubulin alpha chain - mouse 0.0782 0.487 0.7435
Loa Loa (eye worm) Smad1 0.0024 0.0065 0.0093
Onchocerca volvulus 0.0024 0.0067 0.0252
Echinococcus multilocularis tubulin alpha chain 0.0782 0.487 0.4866
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0519 0.3203 0.4889
Trichomonas vaginalis tubulin gamma chain, putative 0.0608 0.3768 0.5754
Onchocerca volvulus 0.0027 0.0082 0.0333
Onchocerca volvulus 0.0024 0.0067 0.0252
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0305 0.0459
Loa Loa (eye worm) alpha-tubulin 0.0782 0.487 0.7435
Brugia malayi Tubulin gamma chain 0.0608 0.3768 0.5751
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0093 0.0117
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0106 0.0582 0.1358
Echinococcus granulosus Immunoglobulin 0.0021 0.0045 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0099 0.0538 0.0815
Brugia malayi MH2 domain containing protein 0.035 0.2133 0.3253
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.027 0.04
Echinococcus multilocularis tubulin alpha chain 0.0782 0.487 0.4866
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Leishmania major beta tubulin 0.1047 0.6548 1
Echinococcus granulosus tubulin alpha chain 0.0782 0.487 0.7434
Leishmania major zeta tubulin, putative 0.0538 0.3321 0.5066
Trichomonas vaginalis tubulin, putative 0.0319 0.1933 0.2952
Brugia malayi sulfakinin receptor protein 0.0223 0.1325 0.2018
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0024 0.0053
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0067 0.0102
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0109 0.0166
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.027 0.04
Echinococcus multilocularis nuclear receptor nhr 48 0.0047 0.021 0.0202
Mycobacterium leprae Probable lipase LipE 0.0106 0.0582 0.3581
Schistosoma mansoni tyrosine kinase 0.0244 0.1457 0.2219
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.0812 0.1235
Brugia malayi Cytochrome P450 family protein 0.0026 0.0077 0.0111
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0398 0.2431 0.3712
Trypanosoma cruzi epsilon tubulin, putative 0.0608 0.3765 0.5747
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.0541 0.0821
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Brugia malayi MH1 domain containing protein 0.0024 0.0065 0.0093
Brugia malayi hypothetical protein 0.0024 0.0067 0.0096
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0062 0.0088
Echinococcus multilocularis ferritin 0.0018 0.0026 0.0018
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.027 0.0405
Onchocerca volvulus Bile acid receptor homolog 0.0099 0.0541 0.2731
Echinococcus granulosus Tubulin alpha 1 chain 0.0782 0.487 0.7434
Schistosoma mansoni tubulin subunit alpha 0.0782 0.487 0.7435
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0013
Brugia malayi beta-lactamase family protein 0.0106 0.0582 0.0884
Schistosoma mansoni nuclear hormone receptor 0.0099 0.0541 0.082
Leishmania major hypothetical protein, conserved 0.0099 0.0538 0.0811
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.027 0.0406
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0065 0.0093
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0072 0.0368 0.225
Brugia malayi prostaglandin transporter 0.0055 0.0262 0.0394
Brugia malayi orphan nuclear receptor NR2E1 0.0047 0.021 0.0314
Loa Loa (eye worm) hypothetical protein 0.0209 0.1237 0.1885
Brugia malayi Integrin beta pat-3 precursor 0.0309 0.1868 0.2849
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0062 0.0233
Schistosoma mansoni Smad4 0.0024 0.0065 0.0092
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0209 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0099 0.0541 0.0534
Loa Loa (eye worm) tubulin beta-4 chain 0.1047 0.6548 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0062 0.0292
Brugia malayi Isocitrate dehydrogenase 0.0062 0.0305 0.046
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0305 0.0454
Loa Loa (eye worm) fibroinase 0.0016 0.0018 0.0022
Loa Loa (eye worm) tubulin beta-2A chain 0.1047 0.6548 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0853 0.1298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0122
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0099 0.0541 0.0821
Plasmodium falciparum tubulin gamma chain 0.0608 0.3768 0.5743
Trypanosoma cruzi zeta tubulin, putative 0.0538 0.3321 0.5068
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1047 0.6548 0.6545
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Echinococcus granulosus beta tubulin 0.1047 0.6548 1
Leishmania major beta tubulin 0.1047 0.6548 1
Schistosoma mansoni tubulin subunit beta 0.1047 0.6548 1
Echinococcus multilocularis tubulin epsilon chain 0.0608 0.3765 0.376
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0062
Toxoplasma gondii patched family protein 0.0024 0.0067 0.0094
Schistosoma mansoni tubulin subunit alpha 0.0263 0.158 0.2408
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0018 0.001
Brugia malayi protein-tyrosine kinase 0.0042 0.0178 0.0266
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0152 0.0224
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0089
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0122 0.0114
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0018 0.0026 0.0061
Loa Loa (eye worm) hypothetical protein 0.0106 0.0582 0.0884
Echinococcus multilocularis tubulin alpha 3 chain 0.0782 0.487 0.4866
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0198 0.0294
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0016 0.0025
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0052 0.0245 0.0363
Echinococcus multilocularis cysteine protease 0.0016 0.0018 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0245 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.027 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0099 0.0541 0.0821
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0178 0.0265
Trichomonas vaginalis tubulin epsilon chain, putative 0.0782 0.487 0.7437
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0122 0.0174
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0198 0.0296
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0065 0.0093
Echinococcus multilocularis protein patched 0.0171 0.0994 0.0987
Echinococcus granulosus tyrosine kinase 0.0042 0.0178 0.026
Brugia malayi isocitrate dehydrogenase 0.0062 0.0305 0.046
Trichomonas vaginalis tubulin epsilon chain, putative 0.0263 0.158 0.2413
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0048 0.022 0.0212
Echinococcus granulosus tyrosine protein kinase ABL1 0.0216 0.1283 0.195
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0255 0.1529 0.2329
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1515 0.2314
Loa Loa (eye worm) nuclear hormone receptor 0.0047 0.021 0.0314
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0145 0.0213
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0018 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0099 0.0541 0.0821
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0178 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0194 0.0297
Plasmodium falciparum alpha tubulin 2 0.0782 0.487 0.7431
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.008 0.0114
Brugia malayi photoreceptor-specific nuclear receptor 0.0099 0.0541 0.0821
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0326 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Leishmania major beta tubulin 0.1047 0.6548 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0048 0.022 0.0212
Brugia malayi Cathepsin L-like precursor 0.0016 0.0018 0.0022
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.027 0.0388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0137 0.0209
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.025 0.1497 0.2277
Echinococcus granulosus tumor protein p63 0.0333 0.2022 0.308
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0319 0.1933 0.2952
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0361 0.054
Echinococcus granulosus cpg binding protein 0.0063 0.0315 0.047
Loa Loa (eye worm) hypothetical protein 0.0071 0.0363 0.0549
Leishmania major beta tubulin 0.1047 0.6548 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0062 0.0092
Trypanosoma brucei epsilon tubulin 0.0582 0.3599 0.5491
Loa Loa (eye worm) alpha-tubulin 0.0782 0.487 0.7435
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0139 0.0206
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0156 0.0236
Echinococcus granulosus expressed conserved protein 0.0373 0.2279 0.3472
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0137 0.0202
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.021 0.0202
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.027 0.0405
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0152 0.0221
Schistosoma mansoni smad1 5 8 and 0.0024 0.0065 0.0092
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0312 0.0469
Schistosoma mansoni hypothetical protein 0.0048 0.0215 0.0321
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0152 0.0224
Schistosoma mansoni hypothetical protein 0.0044 0.0194 0.0289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Echinococcus multilocularis GPCR, family 2 0.0033 0.0122 0.0114
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0052 0.0245 0.0238
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0152 0.0225
Brugia malayi hypothetical protein 0.0047 0.021 0.0314
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0067 0.009
Echinococcus granulosus tyrosine protein kinase Src64B 0.0048 0.022 0.0324
Brugia malayi nuclear receptor NHR-88 0.0047 0.021 0.0314
Brugia malayi protein C24B5.3 0.0024 0.0067 0.0096
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0139 0.0783
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0062 0.0305 0.0454
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0072 0.0368 0.0539
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0018 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Trypanosoma cruzi beta tubulin, putative 0.1047 0.6548 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0361 0.0354
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0145 0.0215
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0272 0.0404
Echinococcus multilocularis hypothetical protein 0.0782 0.487 0.4866
Echinococcus multilocularis tumor protein p63 0.0333 0.2022 0.2016
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0262 0.0394
Treponema pallidum bacterioferrin (TpF1) 0.0018 0.0026 0.0132
Brugia malayi Myosin head containing protein 0.0024 0.0067 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0093 0.0134
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Onchocerca volvulus 0.0049 0.0223 0.1066
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0052 0.0245 0.0369
Loa Loa (eye worm) patched family protein 0.0024 0.0067 0.0096
Leishmania major beta tubulin 0.1047 0.6548 1
Schistosoma mansoni tyrosine kinase 0.0048 0.022 0.0328
Loa Loa (eye worm) tubulin beta-1 chain 0.1047 0.6548 1
Schistosoma mansoni RAR-like nuclear receptor 0.0099 0.0541 0.082
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.1389 0.1382
Giardia lamblia Alpha-tubulin 0.0782 0.487 0.7431
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0062 0.0305 0.0459
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0194 0.0297
Schistosoma mansoni zinc finger protein 0.0047 0.021 0.0313
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0077 0.0111
Toxoplasma gondii beta-tubulin, putative 0.1047 0.6548 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0048 0.022 0.0324
Leishmania major hypothetical protein, conserved 0.0106 0.0582 0.0878
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0048 0.022 0.0212
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0067 0.0121
Echinococcus granulosus thyroid hormone receptor alpha 0.0047 0.021 0.0309
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.021 0.0309
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0152 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0082 0.0124
Plasmodium vivax patched family protein, putative 0.0024 0.0067 0.0099
Echinococcus granulosus tubulin delta chain 0.0263 0.158 0.2404
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0062 0.0305 0.0454
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0031 0.0036
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0099 0.0541 0.2731
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0077 0.0386
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0067 0.009
Loa Loa (eye worm) tubulin alpha 2 0.0519 0.3203 0.4889
Brugia malayi beta-lactamase family protein 0.0106 0.0582 0.0884
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0263 0.158 1
Onchocerca volvulus 0.0055 0.0262 0.1272
Trypanosoma cruzi zeta tubulin, putative 0.0538 0.3321 0.5068
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0582 0.0889
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Trypanosoma brucei beta tubulin 0.1047 0.6548 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0062 0.0305 0.046
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0093 0.0135
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0123 0.018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0305 0.0297
Plasmodium vivax tubulin alpha chain, putative 0.0782 0.487 0.7436
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0404 0.247 0.3768
Loa Loa (eye worm) hypothetical protein 0.0165 0.0957 0.1456
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0045 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.0099
Mycobacterium tuberculosis Probable esterase LipL 0.0106 0.0582 0.1358
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0099 0.0541 0.082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0008 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Brugia malayi alpha-tubulin 0.0782 0.487 0.7435
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0026 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0082 0.0124
Echinococcus granulosus tyrosine protein kinase Fyn 0.0048 0.022 0.0324
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0198 0.0296
Toxoplasma gondii LsmAD domain-containing protein 0.0099 0.0538 0.0815
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0067 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.027 0.0412
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0031
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.021 0.0202
Trichomonas vaginalis tubulin, putative 0.1047 0.6548 1
Echinococcus granulosus nuclear receptor nhr 48 0.0047 0.021 0.0309
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0106 0.0582 0.0884
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1515 0.2314
Mycobacterium ulcerans hypothetical protein 0.0106 0.0582 0.362
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0063 0.0089
Loa Loa (eye worm) transcription factor SMAD2 0.035 0.2133 0.3253
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.021 0.0309
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0045 0.0037
Brugia malayi Smad1 0.0024 0.0065 0.0093
Trichomonas vaginalis tubulin beta chain, putative 0.0782 0.487 0.7437
Loa Loa (eye worm) TK/INSR protein kinase 0.015 0.0865 0.1316
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0171 0.0163
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0031
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Schistosoma mansoni tubulin subunit beta 0.1047 0.6548 1
Brugia malayi Cell division protein ftsZ 0.0263 0.158 0.2409
Brugia malayi nuclear receptor RXR 0.0047 0.021 0.0314
Brugia malayi beta-lactamase 0.0106 0.0582 0.0884
Trypanosoma brucei zeta tubulin 0.0538 0.3321 0.5066
Toxoplasma gondii beta-1 tubulin, putative 0.1047 0.6548 1
Schistosoma mansoni tyrosine kinase 0.0244 0.1457 0.2219
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0662 0.155
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0067 0.009
Brugia malayi Patched protein homolog 1 0.0024 0.0067 0.0096
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0062 0.0292
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0305 0.0297
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus granulosus Tubulin alpha 1 chain 0.0782 0.487 0.7434
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0072 0.0368 0.0555
Echinococcus granulosus tubulin alpha chain 0.0782 0.487 0.7434
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0064 0.0089
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0145 0.0209
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0038 0.003
Loa Loa (eye worm) BEN-1 protein 0.1047 0.6548 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0122 0.018
Schistosoma mansoni agrin 0.0038 0.0152 0.0224
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0072 0.0368 0.2305
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0067 0.0094
Giardia lamblia GTOR 0.0044 0.0194 0.0273
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0016 0.0013
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0145 0.0209
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) tubulin alpha 2 0.0201 0.1185 0.1804
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0156 0.0214
Loa Loa (eye worm) hypothetical protein 0.0223 0.1325 0.2018
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0194 0.0285
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.021 0.0309
Schistosoma mansoni steroid hormone receptor ad4bp 0.0099 0.0541 0.082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0137 0.0209
Giardia lamblia Beta tubulin 0.1047 0.6548 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0017
Echinococcus multilocularis smad 0.0024 0.0065 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0964 0.1473
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0099 0.0541 0.082
Trichomonas vaginalis esterase, putative 0.0106 0.0582 0.0889
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0024 0.0236
Mycobacterium ulcerans bacterioferritin BfrA 0.0018 0.0026 0.0061
Loa Loa (eye worm) hypothetical protein 0.0171 0.0994 0.1513
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0017
Mycobacterium ulcerans beta-lactamase 0.0106 0.0582 0.362
Schistosoma mansoni ferritin 0.0018 0.0026 0.0032
Trichomonas vaginalis tubulin beta chain, putative 0.0782 0.487 0.7437
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0587 0.1369
Brugia malayi nuclear receptor RXR 0.0052 0.0245 0.0369
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0088
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0062 0.0292
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.0211 0.0316
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0194 0.0187
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0093 0.0085
Mycobacterium tuberculosis Probable lipase LipD 0.0106 0.0582 0.1358
Echinococcus granulosus tubulin beta 1 chain 0.1047 0.6548 1
Echinococcus granulosus tubulin alpha chain 0.0782 0.487 0.7434
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.027 0.0262
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.1389 0.2112
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0099 0.0541 0.082
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0067 0.0391
Brugia malayi hypothetical protein 0.0024 0.0067 0.0096
Onchocerca volvulus 0.0024 0.0067 0.0252
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0305 0.0454
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.0541 0.0534
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0137 0.0198
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0048 0.022 0.0212
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Mycobacterium tuberculosis Probable reductase 0.0106 0.0587 0.1369
Echinococcus granulosus neuropeptide s receptor 0.0467 0.287 0.4376
Loa Loa (eye worm) hypothetical protein 0.0782 0.487 0.7435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Toxoplasma gondii alpha-tubulin I, putative 0.0782 0.487 0.7435
Echinococcus multilocularis tyrosine protein kinase Abl 0.0097 0.053 0.0522
Trichomonas vaginalis tubulin, putative 0.029 0.1749 0.2671
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.0812 0.0805
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Loa Loa (eye worm) hypothetical protein 0.0026 0.0079 0.0115
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0031
Toxoplasma gondii alpha tubulin TUBA1 0.0782 0.487 0.7435
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Schistosoma mansoni tubulin subunit beta 0.1047 0.6548 1
Leishmania major beta tubulin 0.1047 0.6548 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0217 0.0325
Brugia malayi Cathepsin L-like precursor 0.0016 0.0018 0.0022
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0048 0.022 0.0324
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0719 0.1092
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0262 0.0393
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0582 0.0882
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0016 0.0017
Brugia malayi intermediate filament protein 0.0027 0.0082 0.0119
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0253 0.1515 0.2309
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0119
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0312 0.0469
Plasmodium falciparum ataxin-2 like protein, putative 0.0099 0.0538 0.0799
Echinococcus granulosus tyrosine protein kinase Src42A 0.0048 0.022 0.0324
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0272 0.1635
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0072 0.0368 0.056
Brugia malayi Nuclear hormone receptor E75 0.0047 0.021 0.0314
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0178 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0008 0.0012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0099 0.0541 0.0815
Schistosoma mansoni hypothetical protein 0.0164 0.0955 0.1453
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0106 0.0582 0.0884
Schistosoma mansoni organic anion transporter 0.0055 0.0262 0.0393
Schistosoma mansoni nuclear hormone receptor 0.0047 0.021 0.0313
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0194 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0099 0.0541 0.0821
Echinococcus granulosus tubulin gamma 1 chain 0.0608 0.3768 0.5749
Trypanosoma brucei hypothetical protein, conserved 0.0106 0.0582 0.0878
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Loa Loa (eye worm) nuclear receptor NHR-67 0.0047 0.021 0.0314
Leishmania major gamma-tubulin 0.0608 0.3768 0.5749
Schistosoma mansoni vesicular amine transporter 0.0021 0.0045 0.006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0089
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Trichomonas vaginalis tubulin epsilon chain, putative 0.1047 0.6548 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0103 0.0569 0.0858
Loa Loa (eye worm) beta-tubulin 0.1047 0.6548 1
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0209 0.0313
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.0571 0.0866
Trichomonas vaginalis tubulin alpha chain, putative 0.0319 0.1933 0.2952
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0077 0.0109
Loa Loa (eye worm) hypothetical protein 0.0106 0.0582 0.0884
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0072 0.0368 0.225
Loa Loa (eye worm) acetyltransferase 0.0142 0.0812 0.1235
Onchocerca volvulus Protein patched homolog 0.0024 0.0067 0.0252
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0044 0.0194 0.0186
Onchocerca volvulus 0.0027 0.0082 0.0333
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0099 0.0541 0.0821
Echinococcus multilocularis Tubulin beta 2C chain 0.1047 0.6548 0.6545
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0047 0.021 0.0314
Onchocerca volvulus 0.0024 0.0067 0.0252
Brugia malayi Tubulin beta chain 0.0319 0.1933 0.2947
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0072 0.0368 0.0555
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0198 0.029
Onchocerca volvulus 0.0055 0.0262 0.1272
Echinococcus granulosus tubulin alpha chain 0.0782 0.487 0.7434
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0316
Schistosoma mansoni tubulin subunit alpha 0.0782 0.487 0.7435
Brugia malayi conserved hypotetical protein 0.0047 0.021 0.0314
Echinococcus multilocularis integrin beta 2 0.0229 0.1362 0.1355
Brugia malayi nuclear hormone receptor 0.0047 0.021 0.0314
Leishmania major beta tubulin 0.1047 0.6548 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0072 0.0368 0.0551
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0016 0.0025
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0178 0.017
Echinococcus granulosus agrin 0.0038 0.0152 0.0219
Onchocerca volvulus 0.0038 0.0152 0.0695
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0194 0.0285
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0008 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.0541 0.0815
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0099 0.0541 0.0821
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0018 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.035 0.2133 0.3253
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0326 0.049
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0031 0.0023
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0045 0.006
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0099 0.0541 0.0821
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0099 0.0541 0.0534
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0077 0.0111
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0272 0.1635
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.0541 0.0821
Brugia malayi Patched related family protein 4 0.0024 0.0067 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1515 0.2314
Loa Loa (eye worm) hypothetical protein 0.0106 0.0582 0.0884
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0018 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0368 0.0551
Echinococcus multilocularis neuropeptide receptor A26 0.0467 0.287 0.2864
Brugia malayi hypothetical protein 0.0233 0.1389 0.2117
Echinococcus granulosus Tubulin beta 2C chain 0.1047 0.6548 1
Schistosoma mansoni coup transcription factor 0.0099 0.0541 0.082
Brugia malayi hypothetical protein 0.0047 0.021 0.0314
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus multilocularis expressed protein 0.0038 0.0152 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0122 0.018
Loa Loa (eye worm) glutathione reductase 0.0047 0.0209 0.0313
Echinococcus multilocularis 0.0142 0.0812 0.0805
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0008 0.0005
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0582 0.3599 0.5493
Echinococcus multilocularis beta LACTamase domain containing family member 0.0106 0.0582 0.0575
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0067 0.0094
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0082 0.0119
Schistosoma mansoni hypothetical protein 0.0033 0.0122 0.0179
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0016 0.0018
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Onchocerca volvulus 0.0106 0.0582 0.2946
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) hypothetical protein 0.0028 0.0093 0.0135
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Brugia malayi Protein kinase domain containing protein 0.015 0.0865 0.1316
Echinococcus granulosus tubulin subunit TubB 0.0782 0.487 0.7434
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0016 0.0013
Mycobacterium ulcerans bacterioferritin BfrB 0.0018 0.0026 0.0061
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0272 0.0404
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0152 0.0144
Entamoeba histolytica tubulin family protein 0.1047 0.6548 1
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Onchocerca volvulus 0.0024 0.0067 0.0252
Trypanosoma brucei tubulin gamma chain 0.0608 0.3768 0.5749
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0005 0.0005
Echinococcus multilocularis tubulin alpha chain 0.0782 0.487 0.4866
Giardia lamblia Alpha-tubulin 0.0782 0.487 0.7431
Trypanosoma brucei alpha tubulin 0.0782 0.487 0.7434
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0136 0.0196
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0582 0.0889
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0018 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.0099 0.0541 0.0534
Onchocerca volvulus 0.0048 0.0215 0.1026
Echinococcus multilocularis Tubulin beta 2C chain 0.1047 0.6548 0.6545
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Echinococcus multilocularis agrin 0.0038 0.0152 0.0144
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0072 0.0368 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0312 0.0469
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.027 0.0262
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0262 0.1272
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0018 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Brugia malayi nuclear receptor NHR-88 0.0099 0.0541 0.0821
Loa Loa (eye worm) TK/ABL protein kinase 0.0216 0.1283 0.1955
Brugia malayi MH2 domain containing protein 0.0024 0.0065 0.0093
Trichomonas vaginalis tubulin beta chain, putative 0.0782 0.487 0.7437
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0662 0.155
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0099 0.0541 0.0815
Schistosoma mansoni hypothetical protein 0.0033 0.0122 0.0179
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0062 0.0292
Onchocerca volvulus 0.0099 0.0541 0.2731
Entamoeba histolytica tubulin gamma chain 0.0608 0.3768 0.5753
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0067 0.009
Onchocerca volvulus 0.0055 0.0262 0.1272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0099 0.0541 0.0821
Schistosoma mansoni cpg binding protein 0.0063 0.0315 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.0099
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Toxoplasma gondii cathepsin CPL 0.0016 0.0018 0.0021
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0305 0.0459
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0262 0.0254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.0571 0.0866
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0326 0.0486
Schistosoma mansoni smad 0.0024 0.0065 0.0092
Echinococcus granulosus integrin alpha ps 0.0032 0.0119 0.017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0062 0.0292
Echinococcus multilocularis Immunoglobulin 0.0021 0.0045 0.0037
Echinococcus granulosus beta tubulin 0.1047 0.6548 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Schistosoma mansoni tubulin subunit epsilon 0.0608 0.3765 0.5747
Brugia malayi Furin-like cysteine rich region family protein 0.0462 0.284 0.4334
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0152 0.0224
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0104 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Brugia malayi protein C24B5.3 0.0024 0.0067 0.0096
Toxoplasma gondii tubulin, putative 0.0026 0.008 0.0115
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0067 0.0077
Echinococcus granulosus follistatin 0.0038 0.0152 0.0219
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0016 0.0013
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0464 0.2851 0.4354
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0326 0.0492
Trichomonas vaginalis tubulin gamma chain, putative 0.0263 0.158 0.2413
Loa Loa (eye worm) TK protein kinase 0.0042 0.0178 0.0266
Echinococcus multilocularis tubulin alpha 1C chain 0.0782 0.487 0.4866
Trypanosoma brucei epsilon tubulin 0.0608 0.3765 0.5745
Loa Loa (eye worm) RecQ helicase 0.0041 0.0171 0.0255
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Loa Loa (eye worm) hypothetical protein 0.0036 0.0145 0.0215
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0099 0.0541 0.0534
Trypanosoma brucei trypanothione reductase 0.0047 0.0209 0.0307
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0198 0.029
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Trypanosoma brucei alpha tubulin 0.0782 0.487 0.7434
Brugia malayi Tubulin alpha-2 chain 0.0782 0.487 0.7435
Loa Loa (eye worm) hypothetical protein 0.0118 0.0663 0.1007
Plasmodium falciparum ataxin-2 like protein, putative 0.0099 0.0538 0.0799
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0016 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Brugia malayi Niemann-Pick C1 protein precursor 0.0398 0.2431 0.3709
Trypanosoma cruzi tubulin delta chain 0.0427 0.2621 0.3999
Giardia lamblia Delta tubulin 0.0263 0.158 0.2395
Echinococcus multilocularis tubulin subunit beta 0.1047 0.6548 0.6545
Echinococcus multilocularis neuroglian 0.0024 0.0063 0.0055
Schistosoma mansoni hypothetical protein 0.0033 0.0122 0.0179
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.021 0.1
Plasmodium vivax delta tubulin, putative 0.0263 0.158 0.2412
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0106 0.0582 0.0884
Echinococcus granulosus tubulin alpha 1C chain 0.0782 0.487 0.7434
Schistosoma mansoni nuclear hormone receptor 0.0047 0.021 0.0313
Echinococcus granulosus neuropeptide receptor A26 0.0467 0.287 0.4376
Schistosoma mansoni follistatin 0.0038 0.0152 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0194 0.0285
Echinococcus granulosus sterol regulatory element binding protein 0.0171 0.0994 0.1508
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.0541 0.0821
Schistosoma mansoni hypothetical protein 0.0124 0.0699 0.1061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0209 0.0201
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0013
Leishmania major cathepsin L-like protease 0.0063 0.0312 0.0465
Schistosoma mansoni hypothetical protein 0.0071 0.0361 0.0545
Onchocerca volvulus 0.0055 0.0262 0.1272
Loa Loa (eye worm) hypothetical protein 0.0052 0.0245 0.0369
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0145 0.0213
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0093 0.0135
Echinococcus granulosus Tubulin beta 2C chain 0.1047 0.6548 1
Echinococcus multilocularis epidermal growth factor receptor 0.0462 0.284 0.2834
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0106 0.0582 0.0884
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0145 0.0209
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0137 0.0198
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0272 0.0264
Brugia malayi Cathepsin L-like precursor 0.0016 0.0018 0.0022
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0178 0.027
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0099 0.0541 0.0821
Leishmania major cathepsin L-like protease 0.0016 0.0018 0.0016
Echinococcus multilocularis tubulin subunit TubB 0.0782 0.487 0.4866
Onchocerca volvulus 0.0106 0.0582 0.2946
Echinococcus multilocularis muscleblind protein 0.0165 0.0957 0.095
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Leishmania major trypanothione reductase 0.0047 0.0209 0.0307
Schistosoma mansoni tyrosine kinase 0.015 0.0865 0.1315
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0018 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.027 0.0412
Brugia malayi Cytochrome P450 family protein 0.0026 0.0077 0.0111
Loa Loa (eye worm) hypothetical protein 0.0027 0.0083 0.0121
Echinococcus granulosus Niemann Pick C1 protein 0.0568 0.3512 0.5358
Schistosoma mansoni hypothetical protein 0.0854 0.5322 0.8127
Leishmania major cathepsin L-like protease 0.0063 0.0312 0.0465
Echinococcus granulosus tubulin alpha 3 chain 0.0782 0.487 0.7434
Brugia malayi Cathepsin L-like precursor 0.0016 0.0018 0.0022
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0272 0.0408
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0582 0.0889
Brugia malayi CHE-14 protein 0.0171 0.0994 0.1513
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0052 0.0245 0.0367
Schistosoma mansoni tyrosine kinase 0.0462 0.284 0.4333
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0103 0.0569 0.0562
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0194 0.0285
Brugia malayi nuclear receptor NHR-67 0.0047 0.021 0.0314
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Echinococcus granulosus Tubulin beta 2C chain 0.1047 0.6548 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0067 0.009
Echinococcus multilocularis Niemann Pick C1 protein 0.0398 0.2431 0.2425
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0145 0.0219
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0262 0.0388
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Entamoeba histolytica tubulin family protein 0.1047 0.6548 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0137 0.0209
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0145 0.0221
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0067 0.0094
Plasmodium falciparum thioredoxin reductase 0.0047 0.0209 0.0295
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0062 0.0305 0.0442
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0119
Schistosoma mansoni organic anion transporter 0.0055 0.0262 0.0393
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0018 0.0028
Trichomonas vaginalis tubulin beta chain, putative 0.0782 0.487 0.7437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0153 0.0234
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0065 0.0092
Schistosoma mansoni integrin beta subunit 0.0182 0.1065 0.162
Loa Loa (eye worm) patched family protein 0.0024 0.0067 0.0096
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0065 0.0087
Entamoeba histolytica tubulin alpha chain, putative 0.0782 0.487 0.7436
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.0541 0.0821
Echinococcus granulosus Protein patched homolog 1 0.0171 0.0994 0.1508
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0017
Echinococcus multilocularis L aminoadipate semialdehyde 0.0255 0.1529 0.1522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.01
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Trichomonas vaginalis tubulin beta chain, putative 0.1047 0.6548 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0326 0.0495
Toxoplasma gondii hypothetical protein 0.0024 0.0067 0.0094
Trichomonas vaginalis tubulin alpha chain, putative 0.0582 0.3599 0.5496
Schistosoma mansoni tyrosine kinase 0.0244 0.1457 0.2219
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.027 0.04
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0062 0.0292
Schistosoma mansoni nuclear receptor 0.0047 0.021 0.0313
Leishmania major beta tubulin 0.1047 0.6548 1
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0171 0.0255
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.0541 0.0815
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0017
Entamoeba histolytica tubulin alpha-1 chain 0.0782 0.487 0.7436
Loa Loa (eye worm) hypothetical protein 0.0035 0.0137 0.0203
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0065 0.0087
Schistosoma mansoni integrin alpha-ps 0.0068 0.0342 0.0515
Leishmania major cathepsin L-like protease 0.0016 0.0018 0.0016
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0093 0.0129
Trypanosoma brucei alpha tubulin 0.0782 0.487 0.7434
Loa Loa (eye worm) hypothetical protein 0.0464 0.2851 0.435
Plasmodium vivax glutathione reductase, putative 0.0047 0.0209 0.0317
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0145 0.0209
Schistosoma mansoni thyroid hormone receptor 0.0223 0.1327 0.202
Brugia malayi Tubulin beta-1 chain 0.1047 0.6548 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0044 0.0194 0.0284
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0067 0.0059
Schistosoma mansoni hypothetical protein 0.0164 0.0955 0.1453
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0048 0.022 0.0212
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0216 0.1283 0.1276
Schistosoma mansoni retinoic acid receptor RXR 0.0196 0.1156 0.176
Loa Loa (eye worm) hypothetical protein 0.0032 0.0119 0.0176
Leishmania major beta tubulin 0.1047 0.6548 1
Loa Loa (eye worm) hypothetical protein 0.0233 0.1389 0.2117
Echinococcus multilocularis sterol regulatory element binding protein 0.0171 0.0994 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0102 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0082 0.0124
Schistosoma mansoni cpg binding protein 0.006 0.0294 0.0441
Mycobacterium leprae cell division protein FtsZ 0.0263 0.158 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0588 0.0892
Brugia malayi hypothetical protein 0.0024 0.0067 0.0096
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0016 0.0017
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0153 0.0883 0.0876
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0109 0.0159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0312 0.0465
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0138 0.013
Loa Loa (eye worm) hypothetical protein 0.0255 0.1529 0.233
Plasmodium falciparum alpha tubulin 1 0.0782 0.487 0.7431
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Echinococcus multilocularis tubulin delta chain 0.0263 0.158 0.1573
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0145 0.0137
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0016 0.0013
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0178 0.0272
Loa Loa (eye worm) hypothetical protein 0.0099 0.0541 0.0821
Plasmodium falciparum tubulin delta chain, putative 0.0263 0.158 0.2395
Brugia malayi nuclear hormone receptor 0.0099 0.0541 0.0821
Brugia malayi Tubulin alpha chain 0.0782 0.487 0.7435
Schistosoma mansoni intermediate filament proteins 0.0027 0.0082 0.0118
Loa Loa (eye worm) hypothetical protein 0.0161 0.0932 0.1418
Trichomonas vaginalis tubulin alpha chain, putative 0.0319 0.1933 0.2952
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0156 0.0214
Brugia malayi Cathepsin L-like precursor 0.0016 0.0018 0.0022
Brugia malayi Integrin alpha pat-2 precursor 0.0151 0.0868 0.132
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0008 0.0006
Echinococcus multilocularis integrin alpha ps 0.0068 0.0342 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Schistosoma mansoni ferritin light chain 0.0018 0.0026 0.0032
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0024 0.002
Schistosoma mansoni integrin alpha-ps 0.0035 0.0137 0.0201
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0152 0.0225
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0957 0.095
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Echinococcus multilocularis tubulin alpha chain 0.0782 0.487 0.4866
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Echinococcus granulosus tm gpcr rhodopsin 0.0523 0.3229 0.4925
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0077 0.0111
Schistosoma mansoni tubulin subunit beta 0.0263 0.158 0.2408
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0018 0.0022
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0067 0.01
Mycobacterium tuberculosis Probable hydrolase 0.0106 0.0582 0.1358
Echinococcus granulosus dnaJ subfamily B 0.0854 0.5322 0.8126
Brugia malayi nuclear hormone receptor family member nhr-6 0.0047 0.021 0.0314
Echinococcus multilocularis Tubulin alpha 1 chain 0.0782 0.487 0.4866
Echinococcus granulosus twitchin 0.0024 0.0066 0.0089
Schistosoma mansoni tubulin subunit beta 0.1047 0.6548 1
Onchocerca volvulus 0.0106 0.0582 0.2946
Echinococcus granulosus tubulin alpha 0.0582 0.3599 0.5491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0022
Schistosoma mansoni tubulin subunit gamma 0.0608 0.3768 0.5751
Onchocerca volvulus 0.0319 0.1933 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.003 0.0034
Loa Loa (eye worm) TK/KIN16 protein kinase 0.003 0.0104 0.0152
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0253 0.1515 0.2309
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0018 0.0021
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0103 0.0569 0.0562
Mycobacterium leprae conserved hypothetical protein 0.0106 0.0582 0.3581
Trypanosoma brucei epsilon tubulin 0.0608 0.3765 0.5745
Trypanosoma cruzi tubulin delta chain 0.0427 0.2621 0.3999
Loa Loa (eye worm) cysteine protease 0.0016 0.0018 0.0022
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0018 0.0016
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0272 0.0409
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Schistosoma mansoni DNA helicase recq5 0.0028 0.0093 0.0134
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0093 0.0134
Toxoplasma gondii thioredoxin reductase 0.0047 0.0209 0.0312
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0062 0.0082
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0262 0.0388
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0067 0.0077
Entamoeba histolytica hypothetical protein 0.0071 0.0361 0.055
Brugia malayi hypothetical protein 0.0055 0.0262 0.0394
Echinococcus granulosus neuroglian 0.0024 0.0063 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0245 0.0369
Trypanosoma brucei beta tubulin 0.0582 0.3599 0.5491
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0519 0.3203 0.4892
Schistosoma mansoni apoferritin-2 0.0018 0.0026 0.0032
Brugia malayi hypothetical protein 0.0099 0.0538 0.0816
Trichomonas vaginalis ferritin, putative 0.0018 0.0026 0.0039
Echinococcus multilocularis beta tubulin 0.1047 0.6548 0.6545
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0523 0.3229 0.3223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0194 0.0297
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0062 0.0088
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0099 0.0541 0.0815
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0018 0.0028
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0139 0.0131
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0048 0.022 0.0212
Brugia malayi CXXC zinc finger family protein 0.006 0.0294 0.0443
Leishmania major cathepsin L-like protease 0.0016 0.0018 0.0016
Schistosoma mansoni ferritin light chain 0.0018 0.0026 0.0032
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0018 0.0003
Brugia malayi Tubulin beta chain 0.0263 0.158 0.2409
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.027 0.0405
Loa Loa (eye worm) BEN-1 protein 0.1047 0.6548 1
Leishmania major cathepsin L-like protease 0.0016 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0099 0.0541 0.0821
Loa Loa (eye worm) ctsf protein 0.0016 0.0018 0.0022
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0018 0.001
Echinococcus granulosus smad 0.0024 0.0065 0.0087
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0541 0.0821
Schistosoma mansoni tubulin subunit delta 0.0263 0.158 0.2408
Loa Loa (eye worm) hypothetical protein 0.0052 0.0245 0.0369
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0144 0.0825 0.0818
Echinococcus granulosus geminin 0.0849 0.5293 0.8081
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0088
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0109 0.0154
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0262 0.0394
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0198 0.019
Onchocerca volvulus 0.0023 0.0062 0.0227
Brugia malayi tailless protein 0.0047 0.021 0.0314
Trypanosoma brucei beta tubulin 0.1047 0.6548 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Giardia lamblia Gamma tubulin 0.0608 0.3768 0.5743
Echinococcus multilocularis Smad4 0.0024 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0018 0.0022
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0099 0.0541 0.0815
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0145 0.0213
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Brugia malayi hypothetical protein 0.0055 0.0262 0.0394
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.01
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0194 0.0289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0065 0.01
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0072 0.0368 0.0844
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0013
Entamoeba histolytica hypothetical protein 0.0071 0.0361 0.055
Brugia malayi Patched family protein 0.0024 0.0067 0.0096
Brugia malayi Patched related family protein 10 0.0024 0.0067 0.0096
Loa Loa (eye worm) SRC-1 0.0048 0.022 0.0329
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0582 0.0889
Onchocerca volvulus 0.0047 0.021 0.1
Loa Loa (eye worm) integrin alpha pat-2 0.0232 0.1385 0.211
Giardia lamblia Beta tubulin 0.1047 0.6548 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0008 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0099 0.0541 0.0821
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0674 0.4184 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0782 0.487 0.7437
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0067 0.0102
Echinococcus multilocularis integrin alpha ps 0.0032 0.0119 0.0111
Trypanosoma brucei alpha tubulin, putative 0.0319 0.1933 0.2943
Mycobacterium tuberculosis Conserved protein 0.0106 0.0582 0.1358
Trichomonas vaginalis tubulin gamma chain, putative 0.1047 0.6548 1
Brugia malayi steroid hormone receptor 0.0099 0.0541 0.0821
Echinococcus granulosus tubulin alpha chain 0.0782 0.487 0.7434
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0198 0.0294
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0018 0.0026
Brugia malayi Fibronectin type III domain containing protein 0.0023 0.0063 0.0089
Toxoplasma gondii beta tubulin 0.1047 0.6548 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0095
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0067 0.0099
Loa Loa (eye worm) hypothetical protein 0.0047 0.021 0.0314
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0065 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0363 0.0549
Plasmodium falciparum lipid/sterol:H+ symporter 0.0024 0.0067 0.0077
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0122 0.0174
Brugia malayi SRC-1 0.0048 0.022 0.0329
Schistosoma mansoni tyrosine kinase 0.021 0.1241 0.1889
Schistosoma mansoni tyrosine kinase 0.0048 0.022 0.0328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.000000000073648 0.00000000011248
Trypanosoma cruzi PAB1-binding protein , putative 0.0099 0.0538 0.0815
Echinococcus granulosus ferritin 0.0018 0.0026 0.0027
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.021 0.1
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0326 0.0318
Echinococcus multilocularis beta tubulin 0.1047 0.6548 0.6545
Entamoeba histolytica hypothetical protein 0.0071 0.0361 0.055
Trichomonas vaginalis tubulin beta chain, putative 0.0319 0.1933 0.2952
Echinococcus multilocularis cpg binding protein 0.0063 0.0315 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0122
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0326 0.049
Brugia malayi Cathepsin L-like precursor 0.0016 0.0018 0.0022
Schistosoma mansoni lamin 0.0027 0.0082 0.0118
Mycobacterium ulcerans hypothetical protein 0.0023 0.0062 0.0292
Echinococcus multilocularis expressed protein 0.0018 0.0026 0.0018
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0062 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1021 0.1559
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.027 0.0412
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0099 0.0541 0.0821
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0662 0.155
Echinococcus multilocularis Tubulin alpha 1 chain 0.0782 0.487 0.4866
Echinococcus granulosus L aminoadipate semialdehyde 0.0255 0.1529 0.2325
Schistosoma mansoni hypothetical protein 0.0164 0.0955 0.1453
Brugia malayi PAS domain containing protein 0.0048 0.0217 0.0326
Loa Loa (eye worm) tubulin alpha-2 chain 0.0782 0.487 0.7435
Echinococcus granulosus integrin alpha ps 0.0068 0.0342 0.051
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0153 0.0883 0.1338
Toxoplasma gondii patched family protein 0.0024 0.0067 0.0094
Brugia malayi hypothetical protein 0.0064 0.0317 0.0478
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0016 0.0022
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0048 0.022 0.0212
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0077 0.0105
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0016 0.0017
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0223 0.0332
Plasmodium vivax vivapain-2 0.0016 0.0018 0.0026
Trichomonas vaginalis tubulin beta chain, putative 0.0782 0.487 0.7437
Brugia malayi MAP kinase sur-1 0.0056 0.027 0.0406
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0145 0.0213
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0067 0.0251
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0008 0.0006
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0093 0.0085
Brugia malayi MH2 domain containing protein 0.0024 0.0065 0.0093
Loa Loa (eye worm) patched family protein 0.0024 0.0067 0.0096
Echinococcus granulosus c src tyrosine kinase 0.002 0.0038 0.0045
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0008
Plasmodium vivax ataxin-2 like protein, putative 0.0099 0.0538 0.082
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0067 0.0059
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0262 0.0394
Onchocerca volvulus 0.0024 0.0067 0.0252
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0326 0.0486
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0587 0.1369
Leishmania major beta tubulin 0.1047 0.6548 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0137 0.0209
Echinococcus granulosus tubulin epsilon chain 0.0608 0.3765 0.5745
Leishmania major cathepsin L-like protease 0.0016 0.0018 0.0016
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0067 0.0095
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.0541 0.0534
Echinococcus granulosus tyrosine protein kinase Fyn 0.0048 0.022 0.0324
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0782 0.487 0.7437
Loa Loa (eye worm) hypothetical protein 0.0083 0.044 0.0667
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0062 0.0088
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.0571 0.0866
Onchocerca volvulus 0.0035 0.0139 0.0628
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0008 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0312 0.0469
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0272 0.0613
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0018 0.0005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0223 0.0334
Trypanosoma brucei alpha tubulin 0.0782 0.487 0.7434
Loa Loa (eye worm) tubulin beta chain 0.1047 0.6548 1
Brugia malayi hypothetical protein 0.0223 0.1325 0.2018
Loa Loa (eye worm) hypothetical protein 0.0038 0.0152 0.0225
Echinococcus multilocularis expressed conserved protein 0.0373 0.2279 0.2273
Loa Loa (eye worm) integrin beta-2 0.0309 0.1868 0.2849
Echinococcus granulosus expressed protein 0.0018 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0055 0.0262 0.0394
Schistosoma mansoni alpha tubulin 0.0782 0.487 0.7435
Toxoplasma gondii ABC1 family protein 0.0106 0.0582 0.0882
Echinococcus granulosus intermediate filament protein 0.0027 0.0082 0.0113
Treponema pallidum NADH oxidase 0.0016 0.0016 0.0071
Brugia malayi Muscleblind-like protein 0.0165 0.0957 0.1456
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0062 0.0305 0.0459
Echinococcus granulosus epidermal growth factor receptor 0.0462 0.284 0.4331
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0262 0.0254
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0047 0.021 0.0313
Leishmania major beta tubulin 0.1047 0.6548 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0123 0.0187
Giardia lamblia Epsilon tubulin 0.0289 0.1746 0.2649
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0114 0.0636 0.0965
Leishmania major alpha tubulin 0.0782 0.487 0.7434
Echinococcus granulosus tubulin alpha 3 chain 0.0782 0.487 0.7434
Echinococcus granulosus Tubulin beta 2C chain 0.1047 0.6548 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0122 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0008 0.0012
Echinococcus multilocularis thyroid hormone receptor alpha 0.0223 0.1327 0.132
Schistosoma mansoni hypothetical protein 0.0849 0.5293 0.8082
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0088
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0587 0.1369
Echinococcus granulosus integrin beta 2 0.0229 0.1362 0.207
Echinococcus granulosus integrin alpha 3 0.0115 0.0645 0.0975
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0152 0.0225
Schistosoma mansoni ferritin 0.0018 0.0026 0.0032
Echinococcus granulosus ecdysone induced protein 78C 0.0099 0.0541 0.0815
Schistosoma mansoni hypothetical protein 0.0033 0.0122 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0018 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0582 0.0882
Brugia malayi tubulin alpha-2 chain 0.0782 0.487 0.7435
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0326 0.0492
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.0039
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0587 0.1369
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0067 0.0102
Schistosoma mansoni survival motor neuron protein 0.0048 0.0215 0.0321
Giardia lamblia Beta tubulin 0.1047 0.6548 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0145 0.0137
Echinococcus multilocularis Tubulin alpha 1 chain 0.0782 0.487 0.4866
Entamoeba histolytica protein kinase, putative 0.0035 0.0136 0.0206

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 25 uM Inhibition of Escherichia coli DdlB ChEMBL. 17267218
MIC (functional) > 256 ug ml-1 Antibacterial activity against Escherichia coli 1411 ChEMBL. 17267218
MIC (functional) > 256 ug ml-1 Antibacterial activity against acrAB deficient Escherichia coli 1411 ChEMBL. 17267218
MIC (functional) > 256 ug ml-1 Antibacterial activity against Staphylococcus aureus 8325-4 ChEMBL. 17267218
MIC (functional) > 256 ug ml-1 Antibacterial activity against Escherichia coli 1411 ChEMBL. 17267218
MIC (functional) > 256 ug ml-1 Antibacterial activity against acrAB deficient Escherichia coli 1411 ChEMBL. 17267218

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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