Detailed information for compound 46206

Basic information

Technical information
  • TDR Targets ID: 46206
  • Name: 4-tert-butyloxolan-2-one
  • MW: 142.196 | Formula: C8H14O2
  • H donors: 0 H acceptors: 1 LogP: 1.81 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1OCC(C1)C(C)(C)C
  • InChi: 1S/C8H14O2/c1-8(2,3)6-4-7(9)10-5-6/h6H,4-5H2,1-3H3
  • InChiKey: FGUZBQZVQHQCFR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-tert-butyltetrahydrofuran-2-one
  • 4-tert-butyl-2-tetrahydrofuranone
  • 22530-95-6
  • NSC135144
  • NSC59879

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia DINP protein human, muc B family 0.002 0.0039 0.0433
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.0207 0.0207
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0091 0.0275 0.0275
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0132 0.2961
Trichomonas vaginalis abcb9, putative 0.0075 0.0221 0.2359
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0047 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0036 0.0036
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0156 0.3537
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0032 0.0077 0.0761
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0094 0.0349
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0074 0.0218 0.0218
Brugia malayi ecdysteroid receptor 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0911 0.3072
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0122 0.1259
Plasmodium falciparum amino acid transporter, putative 0.0015 0.0021 0.0078
Toxoplasma gondii hypothetical protein 0.0015 0.0021 0.0078
Onchocerca volvulus 0.0026 0.0058 0.036
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0035 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0037 0.0037
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0049 0.0133 0.0133
Brugia malayi polk-prov protein 0.003 0.0072 0.0072
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0024 0.005 0.0044
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Leishmania major DNA polymerase eta, putative 0.0014 0.0018 0.0012
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.046 0.1498 0.1493
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0025 0.0021
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0024 0.005 0.1035
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0021
Echinococcus multilocularis multidrug resistance protein 1 0.0075 0.0221 0.0221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Echinococcus multilocularis proliferating cell nuclear antigen 0.0032 0.0077 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.0058
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0132 0.0132
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0075 0.0221 0.0221
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0104 0.2304
Brugia malayi ABC transporter transmembrane region family protein 0.0024 0.005 0.005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0167 0.0167
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0227 0.6247
Schistosoma mansoni agrin 0.0037 0.0094 0.0094
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0104 0.0098
Loa Loa (eye worm) runx1 0.0054 0.015 0.015
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0437 0.0437
Giardia lamblia Multidrug resistance-associated protein 1 0.0024 0.005 0.0546
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.0149 0.0149
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0018 0.0018
Trypanosoma brucei aminopeptidase, putative 0.0014 0.0017 0.0013
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0054 0.0054
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0075 0.0221 0.2359
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0072 0.0068
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0018 0.0018
Entamoeba histolytica ABC transporter, putative 0.0024 0.005 0.0141
Plasmodium falciparum multidrug resistance-associated protein 2 0.0024 0.005 0.0184
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0036 0.0036
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0085 0.0254 0.0254
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0167 0.3791
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0036 0.0036
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.005
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0524 0.1711 0.1711
Plasmodium falciparum transporter, putative 0.0015 0.0021 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.0207 0.0207
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0024 0.005 0.1035
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.004 0.0354
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0021
Schistosoma mansoni thyroid hormone receptor 0.0452 0.1471 0.1471
Brugia malayi multidrug resistance protein 3 0.0075 0.0221 0.0221
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0021 0.0093
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0091 0.0275 0.0275
Schistosoma mansoni hypothetical protein 0.0165 0.0519 0.0519
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0008
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0083 0.0083
Entamoeba histolytica P-glycoprotein 6, putative 0.0024 0.005 0.0141
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Toxoplasma gondii proliferating cell nuclear antigen PCNA1 0.0032 0.0077 0.0285
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0083 0.0083
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0036 0.0036
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0098 0.0298 0.0298
Schistosoma mansoni lipoxygenase 0.0053 0.0149 0.0149
Onchocerca volvulus 0.0019 0.0035 0.0192
Echinococcus multilocularis lamin dm0 0.0026 0.0058 0.0058
Echinococcus multilocularis thyroid hormone receptor alpha 0.0452 0.1471 0.1471
Echinococcus multilocularis geminin 0.0165 0.0519 0.0519
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0075 0.0221 0.0221
Brugia malayi tailless protein 0.0033 0.0083 0.0083
Trichomonas vaginalis abcb9, putative 0.0075 0.0221 0.2359
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0024 0.005 0.0044
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0008 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0034 0.0086 0.0086
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0045 0.0045
Brugia malayi Cytochrome P450 family protein 0.0029 0.0067 0.0067
Echinococcus multilocularis smad 0.0025 0.0054 0.0054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.007 0.007
Leishmania major p-glycoprotein e 0.0024 0.005 0.0044
Echinococcus multilocularis GPCR, family 2 0.0063 0.0182 0.0182
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0094 0.0094
Schistosoma mansoni organic anion transporter 0.0085 0.0254 0.0254
Echinococcus multilocularis 0.001 0.0006 0.0006
Plasmodium vivax sphingomyelin synthase 2, putative 0.0049 0.0133 0.3435
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0094 0.0094
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0021 0.0021
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0075 0.0221 0.0221
Entamoeba histolytica P-glycoprotein-2 0.0075 0.0221 0.0725
Echinococcus multilocularis serotonin transporter 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Brugia malayi Cytochrome P450 family protein 0.001 0.0006 0.0006
Loa Loa (eye worm) nuclear factor I 0.0014 0.0017 0.0017
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0024 0.005 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0104 0.0098
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0083 0.0536
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0528 0.1724 0.1724
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0036 0.0306
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0437 0.0437
Brugia malayi hypothetical protein 0.0015 0.0021 0.0021
Brugia malayi conserved hypotetical protein 0.0033 0.0083 0.0083
Brugia malayi hypothetical protein 0.0019 0.0036 0.0036
Giardia lamblia MRP-like ABC transporter 0.0024 0.005 0.0546
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0271
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0115 0.0352 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.0637 0.0637
Echinococcus multilocularis dna polymerase kappa 0.004 0.0104 0.0104
Brugia malayi Sphingomyelin synthase-related 1 0.0049 0.0133 0.0133
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0036 0.0036
Onchocerca volvulus 0.0033 0.0083 0.0536
Loa Loa (eye worm) hypothetical protein 0.0075 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0036 0.0036
Entamoeba histolytica P-glycoprotein-1 0.0075 0.0221 0.0725
Brugia malayi hypothetical protein 0.0077 0.0227 0.0227
Schistosoma mansoni lipoxygenase 0.0019 0.0035 0.0035
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0024 0.005 0.1035
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0094 0.0349
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0018 0.0018
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.0911 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0083 0.0083
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0207 0.0207
Brugia malayi hypothetical protein 0.0019 0.0036 0.0036
Echinococcus granulosus multidrug resistance protein 1 0.0075 0.0221 0.0221
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0381 0.1236 0.1236
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0104 0.1056
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0039 0.0036
Echinococcus granulosus bloom syndrome protein 0.0021 0.004 0.004
Loa Loa (eye worm) transcription factor SMAD2 0.0364 0.118 0.118
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0014 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.0207 0.0207
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0104 0.0098
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Brugia malayi hypothetical protein 0.005 0.0136 0.0136
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0132 0.0132
Plasmodium falciparum carbonic anhydrase 0.0822 0.2698 1
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0083 0.0083
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0036 0.0036
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0036 0.0036
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0032 0.0118
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0024 0.005 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0045 0.0045
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0098 0.0298 0.0298
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0024 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0063 0.0182 0.0182
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0024 0.005 0.1035
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0018 0.0292
Echinococcus multilocularis musashi 0.0026 0.0058 0.0058
Brugia malayi nuclear receptor RXR 0.0037 0.0096 0.0096
Brugia malayi cytochrome P450 0.001 0.0006 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.0207 0.0207
Schistosoma mansoni kinase 0.0046 0.0126 0.0126
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0083 0.0083
Loa Loa (eye worm) multidrug resistance protein 3 0.0075 0.0221 0.0221
Schistosoma mansoni thyroid hormone receptor 0.0452 0.1471 0.1471
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0068 0.0197 0.0191
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.0096 0.0096
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0036 0.0036
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0083 0.0536
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.0207 0.0207
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0271
Brugia malayi hypothetical protein 0.0033 0.0083 0.0083
Brugia malayi hypothetical protein 0.0037 0.0096 0.0096
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0104 0.01
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0018 0.0012
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0021 0.0021
Echinococcus granulosus cytochrome P450 2K1 0.001 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0011
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0094 0.0094
Onchocerca volvulus 0.0019 0.0035 0.0192
Loa Loa (eye worm) glutamate receptor 1 0.0015 0.002 0.002
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0022 0.0045 0.0045
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0049 0.0133 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0085 0.0254 0.0254
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0049 0.0133 0.0492
Brugia malayi ABC transporter 0.0024 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0429 0.1395 0.1395
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0021 0.0021
Loa Loa (eye worm) agrin synaptic family protein 0.0037 0.0094 0.0094
Brugia malayi hypothetical protein 0.0054 0.0151 0.0151
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0132 0.0132
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0156 0.0156
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0004 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0083 0.0083
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.007 0.007
Brugia malayi Cytochrome P450 family protein 0.001 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0024 0.005 0.0141
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0075 0.0221 0.2359
Trichomonas vaginalis hypothetical protein 0.0049 0.0133 0.1379
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0227 0.0221
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.004 0.004
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.046 0.1498 0.1493
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0036 0.0036
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0182 0.0182
Echinococcus multilocularis Smad4 0.0025 0.0054 0.0054
Trypanosoma brucei polo-like protein kinase 0.0091 0.0275 0.0272
Loa Loa (eye worm) hypothetical protein 0.0037 0.0094 0.0094
Echinococcus granulosus proliferating cell nuclear antigen 0.0032 0.0077 0.0077
Echinococcus multilocularis leucyl aminopeptidase 0.0014 0.0017 0.0017
Echinococcus multilocularis leucine aminopeptidase protein 0.0115 0.0352 0.0352
Loa Loa (eye worm) carbonic anhydrase 3 0.3023 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0562 0.1835 0.1835
Brugia malayi ecdysone receptor 0.0033 0.0083 0.0083
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0024 0.005 0.005
Trypanosoma brucei inositol phosphorylceramide synthase 0.0049 0.0133 0.0129
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0024 0.005 0.0949
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0054 0.0054
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0132 0.0488
Mycobacterium ulcerans leucyl aminopeptidase 0.0115 0.0352 0.8153
Schistosoma mansoni nuclear receptor 0.0033 0.0083 0.0083
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.0207 0.0207
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0271
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0049 0.0133 0.0492
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0132 0.0132
Plasmodium falciparum ABC transporter B family member 7, putative 0.0024 0.005 0.0184
Brugia malayi ABC transporter 0.0023 0.0047 0.0047
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0035 0.0509
Trichomonas vaginalis taga, putative 0.0075 0.0221 0.2359
Brugia malayi hypothetical protein 0.0037 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0133 0.0133
Echinococcus granulosus glutamate receptor 2 0.0022 0.0045 0.0045
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0011
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.0207 0.0207
Onchocerca volvulus 0.0037 0.0094 0.0617
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.007 0.0258
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0014 0.0017 0.0017
Schistosoma mansoni multidrug resistance protein 0.0024 0.005 0.005
Echinococcus multilocularis lamin 0.0026 0.0058 0.0058
Plasmodium vivax ABC transporter B family member 7, putative 0.0024 0.005 0.0949
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0036 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0082 0.0079
Echinococcus multilocularis agrin 0.0037 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0151
Trypanosoma brucei multidrug resistance protein E 0.0024 0.005 0.0046
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0254 0.0254
Schistosoma mansoni multidrug resistance protein 0.0024 0.005 0.005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0083 0.0083
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0083 0.0083
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0104 0.0098
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0022 0.0022
Plasmodium vivax SET domain protein, putative 0.003 0.007 0.1544
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.005 0.0184
Echinococcus granulosus intermediate filament protein 0.0026 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0133 0.1379
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0822 0.2698 0.2698
Entamoeba histolytica P-glyco protein 6, putative 0.0075 0.0221 0.0725
Loa Loa (eye worm) CYP4Cod1 0.001 0.0006 0.0006
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0021 0.0021
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.0207 0.0207
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0024 0.005 0.0046
Brugia malayi MH1 domain containing protein 0.0014 0.0017 0.0017
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0132 0.0126
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0098 0.0298 0.0298
Schistosoma mansoni lozenge 0.0054 0.015 0.015
Brugia malayi CXXC zinc finger family protein 0.0028 0.0064 0.0064
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0075 0.0221 0.0221
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0822 0.2698 0.2698
Echinococcus granulosus ATP binding cassette sub family B 0.0023 0.0047 0.0047
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0024 0.005 0.0044
Schistosoma mansoni hypothetical protein 0.0165 0.0519 0.0519
Echinococcus granulosus expressed protein 0.0377 0.1223 0.1223
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0182 0.0182
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0035 0.0035
Brugia malayi nuclear hormone receptor 0.0071 0.0207 0.0207
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0182 0.0182
Brugia malayi follicle stimulating hormone receptor 0.0224 0.0716 0.0716
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0049 0.0133 0.1379
Schistosoma mansoni hypothetical protein 0.0063 0.0182 0.0182
Echinococcus granulosus sphingomyelin synthase protein 1 0.0049 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Echinococcus multilocularis follistatin 0.0037 0.0094 0.0094
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0021 0.0021
Echinococcus multilocularis NMDA receptor 0.0015 0.002 0.002
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.0207 0.0207
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.043 1
Entamoeba histolytica hypothetical protein 0.0049 0.0133 0.0424
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.046 0.1498 0.1495
Brugia malayi serine/threonine-protein kinase plk-2 0.0091 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Plasmodium vivax ABC transporter B family member 3, putative 0.0024 0.005 0.0949
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0429 0.1395 0.1395
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0227 0.084
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0049 0.0133 0.0133
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0115 0.0352 1
Leishmania major proliferative cell nuclear antigen (PCNA), putative 0.0032 0.0077 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Brugia malayi hypothetical protein 0.0429 0.1395 0.1395
Schistosoma mansoni hypothetical protein 0.0063 0.0182 0.0182
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0094 0.0094
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0254 0.0254
Schistosoma mansoni multidrug resistance protein 0.0075 0.0221 0.0221
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0396 0.1286 0.1286
Loa Loa (eye worm) hypothetical protein 0.0049 0.0133 0.0133
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0094 0.0349
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0036 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Plasmodium falciparum multidrug resistance protein 2 0.0024 0.005 0.0184
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0045 0.0045
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0036 0.0036
Schistosoma mansoni glutamate receptor NMDA 0.0022 0.0045 0.0045
Schistosoma mansoni zinc finger protein 0.0033 0.0083 0.0083
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0083 0.0083
Toxoplasma gondii cytochrome p450 superfamily protein 0.001 0.0006 0.0022
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0008 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0132 0.0132
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0037 0.0037
Echinococcus granulosus ATP binding cassette sub family B 0.0024 0.005 0.005
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0037 0.0037
Loa Loa (eye worm) acetyltransferase 0.014 0.0437 0.0437
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0032 0.0077 0.0071
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.0207 0.0207
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0018 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0072 0.0068
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0014 0.0017 0.0017
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0822 0.2698 0.2698
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Echinococcus granulosus serotonin transporter 0.0015 0.0021 0.0021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Plasmodium vivax ABC transporter B family member 6, putative 0.0024 0.005 0.0949
Plasmodium vivax ABC transporter B family member 4, putative 0.0024 0.005 0.0949
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0167 0.3791
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0038 0.0097 0.0849
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0151 0.1027
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0083 0.0083
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0032 0.0077 0.0071
Loa Loa (eye worm) hypothetical protein 0.0137 0.0426 0.0426
Echinococcus granulosus multidrug resistance associated protein 1 0.0024 0.005 0.005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0018 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0167 0.3791
Plasmodium vivax sphingomyelin synthase 1, putative 0.0049 0.0133 0.3435
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0097 0.1068
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0054 0.0054
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0075 0.0221 0.082
Toxoplasma gondii ABC transporter, putative 0.0024 0.005 0.0184
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Echinococcus multilocularis Protein lozenge 0.0054 0.015 0.015
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0227 0.0223
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0004 0.0004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.0096 0.0096
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0024 0.005 0.0046
Plasmodium falciparum proliferating cell nuclear antigen 1 0.0032 0.0077 0.0285
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.005 0.0184
Onchocerca volvulus Serine\/threonine kinase homolog 0.0091 0.0275 0.1924
Schistosoma mansoni smad1 5 8 and 0.0025 0.0054 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0025 0.0021
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0011
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0075 0.0221 0.082
Loa Loa (eye worm) hypothetical protein 0.0822 0.2698 0.2698
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Entamoeba histolytica P-glycoprotein-2 0.0075 0.0221 0.0725
Echinococcus multilocularis leucyl aminopeptidase 0.0014 0.0017 0.0017
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.0207 0.0207
Trichomonas vaginalis set domain proteins, putative 0.023 0.0735 0.805
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.005
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0058 0.0058
Onchocerca volvulus 0.0015 0.0021 0.0091
Onchocerca volvulus 0.0015 0.0021 0.0091
Echinococcus multilocularis bloom syndrome protein 0.0021 0.004 0.004
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0137 0.0426 0.0426
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0024 0.005 0.1035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Plasmodium falciparum ABC transporter B family member 5, putative 0.0024 0.005 0.0184
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0207 0.0207
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0021 0.0021
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.0207 0.0207
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0132 0.0128
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0104 0.2304
Onchocerca volvulus 0.0075 0.0221 0.1534
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0075 0.0221 0.0221
Echinococcus granulosus ATP binding cassette sub family B 0.0024 0.005 0.005
Schistosoma mansoni lamin 0.0026 0.0058 0.0058
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.0207 0.0207
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.0911 1
Schistosoma mansoni Smad4 0.0025 0.0054 0.0054
Brugia malayi ABC transporter transmembrane region family protein 0.0024 0.005 0.005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Chlamydia trachomatis glutamine binding protein 0.0038 0.0097 0.2283
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0036 0.0036
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0096
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0911 0.3072
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0021 0.0021
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Echinococcus granulosus glutamate receptor subunit protein glur 0.0015 0.002 0.002
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.3023 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.005 0.005
Echinococcus multilocularis expressed protein 0.0037 0.0094 0.0094
Schistosoma mansoni ATP-binding cassette transporter 0.0016 0.0023 0.0023
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0094 0.0349
Toxoplasma gondii protease inhibitor PI2 0.0037 0.0094 0.0349
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.005 0.0184
Brugia malayi Pre-SET motif family protein 0.0202 0.0642 0.0642
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0052 0.0145 0.0145
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.0207 0.0207
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.001 0.0006 0.0002
Loa Loa (eye worm) serotonin transporter b 0.0015 0.0021 0.0021
Plasmodium falciparum ABC transporter B family member 6, putative 0.0024 0.005 0.0184
Brugia malayi hypothetical protein 0.0019 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0019 0.0036 0.0094
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0023 0.0047 0.0047
Schistosoma mansoni carbonic anhydrase-related 0.0822 0.2698 0.2698
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0096
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0018 0.0014
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0201 0.0637 0.0637
Echinococcus multilocularis multidrug resistance associated protein 1 0.0024 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0075 0.0221 0.0221
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0038 0.0097 0.2283
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0156 0.015
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0381 0.1236 0.1236
Trypanosoma brucei proliferative cell nuclear antigen (PCNA), putative 0.0032 0.0077 0.0073
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0075 0.0221 0.2359
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0068 0.0197 0.0191
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0151
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0171 0.0171
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.005 0.0141
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0167 0.0167
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0021
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.3023 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0018
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0015 0.002 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0156 0.3537
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0026
Echinococcus granulosus GPCR family 2 0.0063 0.0182 0.0182
Echinococcus granulosus carbonic anhydrase 0.0822 0.2698 0.2698
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0036 0.0036
Loa Loa (eye worm) solute carrier family 6 member 4 0.0015 0.0021 0.0021
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0032 0.0077 0.1764
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.0207 0.0207
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.0637 0.0637
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0024 0.005 0.0046
Schistosoma mansoni lamin 0.0026 0.0058 0.0058
Echinococcus granulosus FTZ F1 alpha 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0049 0.0133 0.0133
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0006 0.0006
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0151 0.1027
Echinococcus granulosus glutamate NMDA receptor subunit 0.0015 0.002 0.002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0151
Leishmania major p-glycoprotein 0.0075 0.0221 0.0216
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0045 0.0045
Trichomonas vaginalis ABC transporter, putative 0.0075 0.0221 0.2359
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.0207 0.0207
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0088 0.0088
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.0207 0.0207
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0036 0.0036
Chlamydia trachomatis cytosol aminopeptidase 0.0115 0.0352 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0094 0.0094
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0011
Onchocerca volvulus 0.0054 0.0151 0.1027
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0036 0.0306
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0207 0.0207
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0083 0.0083
Onchocerca volvulus 0.0054 0.0151 0.1027
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.1286 0.1286
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0086 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0035 0.0035
Echinococcus granulosus multidrug resistance protein 1 0.0052 0.0146 0.0146
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.0207 0.0207
Schistosoma mansoni glutamate receptor NMDA 0.0015 0.002 0.002
Entamoeba histolytica proliferating cell nuclear antigen, putative 0.0032 0.0077 0.0234
Loa Loa (eye worm) ABC transporter 0.0024 0.005 0.005
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0015 0.002 0.002
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0115 0.0352 0.8153
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0036 0.0306
Brugia malayi Smad1 0.0025 0.0054 0.0054
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0104 0.1056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.043 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0037 0.0037
Brugia malayi cytosol aminopeptidase 0.0014 0.0017 0.0017
Echinococcus granulosus cpg binding protein 0.0029 0.0069 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.007 0.007
Echinococcus granulosus Solute carrier organic anion transporter family 0.0054 0.0151 0.0151
Brugia malayi nuclear receptor NHR-88 0.0033 0.0083 0.0083
Schistosoma mansoni glutamate receptor kainate 0.0015 0.002 0.002
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0822 0.2698 0.2698
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0083 0.0083
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0132 0.0126
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0182 0.0182
Loa Loa (eye worm) ABC transporter 0.0024 0.005 0.005
Schistosoma mansoni multidrug resistance protein 0.0023 0.0047 0.0047
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0036 0.0306
Leishmania major ABC-thiol transporter 0.0024 0.005 0.0044
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0036 0.0306
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0075 0.0221 0.0221
Brugia malayi secreted modular calcium-binding protein 1 0.0037 0.0094 0.0094
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0035 0.0035
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0075 0.0221 0.2359
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.0207 0.0207
Loa Loa (eye worm) histone methyltransferase 0.001 0.0004 0.0004
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.0207 0.0207
Onchocerca volvulus 0.0033 0.0083 0.0536
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Schistosoma mansoni cytochrome P450 0.001 0.0006 0.0006
Leishmania major pentamidine resistance protein 1 0.0024 0.005 0.0044
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0039 0.0034
Entamoeba histolytica hypothetical protein 0.0019 0.0036 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.0207 0.0207
Echinococcus granulosus dna polymerase kappa 0.004 0.0104 0.0104
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.3023 1 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0132 0.0132
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Schistosoma mansoni intermediate filament proteins 0.0026 0.0058 0.0058
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0036 0.0036
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0008 0.0008
Plasmodium falciparum proliferating cell nuclear antigen 2 0.0017 0.0028 0.0104
Trypanosoma cruzi multidrug resistance protein E, putative 0.0024 0.005 0.0044
Echinococcus multilocularis carbonic anhydrase 0.0822 0.2698 0.2698
Loa Loa (eye worm) norepinephrine transporter 0.0015 0.0021 0.0021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0822 0.2698 0.2698
Brugia malayi Glutamate receptor 2 precursor 0.0015 0.002 0.002
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0021 0.0021
Brugia malayi hypothetical protein 0.0054 0.0151 0.0151
Brugia malayi MH1 domain containing protein 0.0025 0.0054 0.0054
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0015 0.002 0.002
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0049 0.0133 0.0133
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.3023 1 1
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0058 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Entamoeba histolytica P-glycoprotein 6, putative 0.0024 0.005 0.0141
Trichomonas vaginalis abcb9, putative 0.0075 0.0221 0.2359
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0426 0.0426
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0036 0.0036
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0024 0.005 0.005
Onchocerca volvulus 0.0429 0.1395 1
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.0207 0.0207
Brugia malayi ABC transporter family protein 0.0024 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0074 0.0218 0.0218
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0167 0.0167
Giardia lamblia ABC transporter, putative 0.0024 0.005 0.0546
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0083 0.0083
Schistosoma mansoni smdr2 0.0075 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0037 0.0094 0.0094
Entamoeba histolytica hypothetical protein 0.0019 0.0036 0.0094
Schistosoma mansoni multidrug resistance protein 0.0024 0.005 0.005
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0036 0.0036
Onchocerca volvulus 0.023 0.0735 0.5239
Schistosoma mansoni nuclear receptor 0.0033 0.0083 0.0083
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.0207 0.1433
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0018 0.0018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.0207 0.0207
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0097 0.036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0098 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0151
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0227 0.0221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0132 0.0132
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0156 0.0156
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0083 0.0083
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0049 0.0133 0.1379
Entamoeba histolytica hypothetical protein 0.0049 0.0133 0.0424
Entamoeba histolytica hypothetical protein 0.0049 0.0133 0.0424
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0424 0.0424
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0054 0.0151 0.0151
Plasmodium falciparum M17 leucyl aminopeptidase 0.0068 0.0197 0.0731
Brugia malayi isocitrate dehydrogenase 0.0048 0.0132 0.0132
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.005 0.0141
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0075 0.0221 0.0221
Trypanosoma cruzi MFS transporter, putative 0.0054 0.0151 0.0145
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0052 0.0146 0.1524
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0014 0.0017 0.0017
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0049 0.0133 0.0129
Onchocerca volvulus 0.0054 0.0151 0.1027
Brugia malayi proliferating cell nuclear antigen (PCNA) 0.0032 0.0077 0.0077
Onchocerca volvulus 0.0085 0.0254 0.1773
Brugia malayi Glutamate receptor 1 precursor 0.0015 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0098 0.0298 0.0298
Brugia malayi nuclear receptor RXR 0.0033 0.0083 0.0083
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0156 0.0156
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0096
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0049 0.0133 0.1379
Brugia malayi Doublecortin family protein 0.0019 0.0035 0.0035
Brugia malayi steroid hormone receptor 0.0071 0.0207 0.0207
Echinococcus granulosus carbonic anhydrase 0.0822 0.2698 0.2698
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Echinococcus multilocularis multidrug resistance protein 1 0.0052 0.0146 0.0146
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.0275 0.027
Schistosoma mansoni multidrug resistance protein 0.0075 0.0221 0.0221
Echinococcus granulosus multidrug resistance protein 1 0.0052 0.0146 0.0146
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0429
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0085 0.0254 0.0254
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0083 0.0083
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0109 0.0403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0024 0.005 0.0044
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0167 0.3791
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.005 0.0141
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.005 0.005
Brugia malayi hypothetical protein 0.0024 0.005 0.005
Entamoeba histolytica P-glycoprotein 5, putative 0.0075 0.0221 0.0725
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0036 0.0036
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0021 0.0021
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0822 0.2698 0.2698
Brugia malayi P-glycoprotein-like protein 0.0024 0.005 0.005
Plasmodium falciparum ABC transporter B family member 4, putative 0.0024 0.005 0.0184
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0024 0.005 0.0044
Leishmania major DNA polymerase kappa, putative 0.002 0.0039 0.0034
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0024 0.005 0.0044
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0047 0.0132
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0036 0.0036
Loa Loa (eye worm) RecQ helicase 0.0021 0.004 0.004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0018 0.0018
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0109 0.0109
Echinococcus granulosus leucyl aminopeptidase 0.0014 0.0017 0.0017
Echinococcus granulosus lamin 0.0026 0.0058 0.0058
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0083 0.0083
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0083 0.0083
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0097 0.0303
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0036 0.0036
Toxoplasma gondii hypothetical protein 0.0049 0.0133 0.0492
Echinococcus multilocularis glutamate receptor 2 0.0015 0.002 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0109 0.1112
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0098 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Brugia malayi Pre-SET motif family protein 0.003 0.007 0.007
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0227 0.084
Loa Loa (eye worm) glutamate receptor 2 0.0015 0.002 0.002
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0014 0.0017 0.0017
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.0275 0.027
Entamoeba histolytica hypothetical protein 0.0035 0.0088 0.0271
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0021 0.0021
Brugia malayi prostaglandin transporter 0.0054 0.0151 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.0207 0.0207
Trichomonas vaginalis ABC transporter, putative 0.0075 0.0221 0.2359
Brugia malayi ABC transporter family protein 0.0024 0.005 0.005
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0075 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0036 0.0306
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0207 0.0207
Echinococcus granulosus geminin 0.0165 0.0519 0.0519
Toxoplasma gondii ABC transporter family protein 0.0024 0.005 0.0184
Entamoeba histolytica hypothetical protein 0.0049 0.0133 0.0424
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0054 0.0054
Schistosoma mansoni DNA polymerase eta 0.0014 0.0018 0.0018
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0036 0.0036
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0035 0.0035
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0024 0.005 0.1035
Brugia malayi hypothetical protein 0.0019 0.0035 0.0035
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0054 0.0054
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0015 0.002 0.002
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0151 0.1027
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0075 0.0221 0.0221
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0109 0.0403
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.0207 0.0207
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0018 0.0018
Brugia malayi hypothetical protein 0.0035 0.0088 0.0088
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0207 0.0207
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.0207 0.0207
Schistosoma mansoni proliferating cell nuclear antigen 0.0032 0.0077 0.0077
Brugia malayi PXA domain containing protein 0.0019 0.0036 0.0036
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.0207 0.0207
Brugia malayi MH2 domain containing protein 0.0011 0.0008 0.0008
Schistosoma mansoni rab6-interacting 0.0019 0.0035 0.0035
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0032 0.0077 0.0761
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0528 0.1724 0.1724
Echinococcus granulosus multidrug resistance protein 1 0.0075 0.0221 0.0221
Trypanosoma brucei carbonic anhydrase-like protein 0.3023 1 1
Brugia malayi MH1 domain containing protein 0.0014 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0047 0.0429
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0024 0.005 0.1035
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0021 0.0021
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0437 0.0437
Trypanosoma brucei p-glycoprotein 0.0024 0.005 0.0046
Onchocerca volvulus 0.0071 0.0207 0.1433
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0132 0.0488
Onchocerca volvulus 0.0015 0.0021 0.0091
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0037 0.0037
Entamoeba histolytica P-glycoprotein-5 0.0075 0.0221 0.0725
Brugia malayi Putative carbonic anhydrase 5 precursor 0.3023 1 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0039 0.0791
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0024 0.005 0.0044
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.3023 1 1
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0036 0.0036
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0151
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0075 0.0221 0.0216
Brugia malayi ABC transporter transmembrane region family protein 0.0023 0.0047 0.0047
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0049 0.0133 0.1379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0024 0.005 0.0949
Echinococcus granulosus carbonic anhydrase II 0.3023 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0224 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Schistosoma mansoni glutamate receptor kainate 0.0015 0.002 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0161 0.0599
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0064 0.0064
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0132 0.0132
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0049 0.0133 0.0133
Echinococcus multilocularis carbonic anhydrase 0.0822 0.2698 0.2698
Entamoeba histolytica hypothetical protein, conserved 0.0897 0.2946 1
Brugia malayi ABC transporter family protein 0.0075 0.0221 0.0221
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0008 0.0003
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0075 0.0221 0.6045
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Echinococcus granulosus leucine aminopeptidase protein 0.0115 0.0352 0.0352
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0167 0.0167
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0018 0.0065
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0021 0.0021
Echinococcus granulosus lamin dm0 0.0026 0.0058 0.0058
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0156 0.0156
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.005 0.0184
Schistosoma mansoni organic anion transporter 0.0054 0.0151 0.0151
Schistosoma mansoni leucine aminopeptidase 0.0014 0.0017 0.0017
Echinococcus multilocularis 0.0024 0.005 0.005
Plasmodium vivax amine transporter, putative 0.0015 0.0021 0.0093
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.0149 0.0149
Schistosoma mansoni coup transcription factor 0.0071 0.0207 0.0207
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0132 0.0128
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0024 0.005 0.0044
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0075 0.0221 0.2359
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0132 0.3398
Leishmania major carbonic anhydrase-like protein 0.3023 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.005 0.0141
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0429
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0429
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.007 0.007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Brugia malayi hypothetical protein 0.0033 0.0083 0.0083
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0151 0.0151
Toxoplasma gondii leucyl aminopeptidase LAP 0.0115 0.0352 0.1305
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0014 0.0017 0.0017
Schistosoma mansoni Smad4 0.0011 0.0008 0.0008
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0021 0.0021
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0064 0.0064
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.002 0.002
Echinococcus multilocularis ATP binding cassette sub family B 0.0074 0.0218 0.0218
Mycobacterium ulcerans hypothetical protein 0.0105 0.0321 0.7413
Brugia malayi intermediate filament protein 0.0026 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0096
Giardia lamblia Multidrug resistance-associated protein 1 0.0023 0.0047 0.0516
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.0007 0.0027
Onchocerca volvulus 0.0085 0.0254 0.1773
Echinococcus granulosus nmda type glutamate receptor 0.0052 0.0145 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0036 0.0306
Echinococcus multilocularis carbonic anhydrase 0.0822 0.2698 0.2698
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0008 0.0008
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0049 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0207 0.0207
Echinococcus granulosus carbonic anhydrase 0.0822 0.2698 0.2698
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0068 0.0197 0.0191
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Schistosoma mansoni multidrug resistance protein 0.0024 0.005 0.005
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0035 0.013
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.043 1
Schistosoma mansoni follistatin 0.0037 0.0094 0.0094
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0008 0.0008
Echinococcus granulosus smad 0.0025 0.0054 0.0054
Echinococcus granulosus dnaJ subfamily B 0.0396 0.1286 0.1286
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0037 0.0037
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.0207 0.0207
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0109 0.2713
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0023 0.0047 0.0516
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0104 0.01
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0207 0.0207
Echinococcus multilocularis expressed protein 0.0377 0.1223 0.1223
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Trypanosoma brucei unspecified product 0.0033 0.0082 0.0079
Brugia malayi Cytochrome P450 family protein 0.001 0.0006 0.0006
Schistosoma mansoni polycystin 1-related 0.0019 0.0035 0.0035
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0167 0.0618
Loa Loa (eye worm) cytochrome P450 0.001 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0063 0.0182 0.0182
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0047
Echinococcus granulosus follistatin 0.0037 0.0094 0.0094
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0036 0.0036
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0049 0.0133 0.0133
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0003 0.0003
Onchocerca volvulus 0.0028 0.0064 0.04
Schistosoma mansoni smad 0.0011 0.0008 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0083 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0275 0.2957
Toxoplasma gondii proliferating cell nuclear antigen PCNA2 0.0017 0.0028 0.0104
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.0637 0.0637
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0083 0.0083
Brugia malayi SPARC precursor 0.0037 0.0094 0.0094
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0047
Schistosoma mansoni carbonic anhydrase-related 0.0822 0.2698 0.2698
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.002 0.002
Echinococcus granulosus Smad4 0.0025 0.0054 0.0054
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.0207 0.1433
Entamoeba histolytica multidrug resistance protein, putative 0.0024 0.005 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0207 0.0207
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0036 0.0036
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0156 0.3537
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Schistosoma mansoni cpg binding protein 0.0029 0.0069 0.0069
Echinococcus granulosus RUN 0.0019 0.0035 0.0035
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0182 0.0182
Echinococcus granulosus multidrug resistance associated protein 7 0.0024 0.005 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0045 0.0045
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0017 0.0028 0.0298
Schistosoma mansoni loxhd1 0.0019 0.0035 0.0035
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0035 0.0088 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0037 0.0037
Schistosoma mansoni smad1 5 8 and 0.0025 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0036
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0036 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.007 0.007
Plasmodium vivax multidrug resistance protein 2, putative 0.0024 0.005 0.0949
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0015 0.002 0.002
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0036 0.0036
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.005 0.0184
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0021
Echinococcus multilocularis multidrug resistance associated protein 7 0.0024 0.005 0.005
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0035 0.0035
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0822 0.2698 0.2698
Trichomonas vaginalis ABC transporter, putative 0.0075 0.0221 0.2359
Leishmania major hypothetical protein, conserved 0.0077 0.0227 0.0221
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0008 0.0008
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0021 0.0078
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.0207 0.0207
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0035 0.0035
Toxoplasma gondii hypothetical protein 0.0015 0.0021 0.0078
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0026 0.0026
Schistosoma mansoni carbonic anhydrase 0.0822 0.2698 0.2698
Loa Loa (eye worm) DR-78 0.0033 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.0207 0.0207
Plasmodium falciparum multidrug resistance protein 1 0.0075 0.0221 0.082
Plasmodium falciparum ABC transporter B family member 3, putative 0.0024 0.005 0.0184
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0012
Schistosoma mansoni multidrug resistance protein 0.0024 0.005 0.005
Trypanosoma brucei cytochrome P450, putative 0.001 0.0006 0.0002
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0024 0.005 0.0046
Schistosoma mansoni glutamate receptor kainate 0.0015 0.002 0.002
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0083 0.0083
Schistosoma mansoni cpg binding protein 0.0028 0.0064 0.0064
Schistosoma mansoni proliferating cell nuclear antigen 0.0032 0.0077 0.0077
Echinococcus multilocularis carbonic anhydrase II 0.3023 1 1
Brugia malayi multidrug resistance related protein 1 0.0024 0.005 0.005
Plasmodium vivax ABC transporter B family member 5, putative 0.0024 0.005 0.0949
Schistosoma mansoni hypothetical protein 0.0063 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0037 0.0094 0.0094
Loa Loa (eye worm) MH2 domain-containing protein 0.0364 0.118 0.118
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0036 0.0036
Onchocerca volvulus 0.003 0.007 0.0441
Giardia lamblia Hypothetical protein 0.0023 0.0047 0.0516
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0091 0.0275 0.0275
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0822 0.2698 0.2698
Schistosoma mansoni smdr1 0.0024 0.005 0.005
Echinococcus multilocularis leucyl aminopeptidase 0.0014 0.0017 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0049 0.0133 0.0133
Giardia lamblia PcnA 0.0032 0.0077 0.0845
Schistosoma mansoni Smad4 0.0011 0.0008 0.0008
Onchocerca volvulus 0.0015 0.0021 0.0091
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0008 0.0008
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.005 0.0184
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) proliferating cell nuclear antigen 0.0032 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.001 0.0006 0.0006
Brugia malayi MH1 domain containing protein 0.0025 0.0054 0.0054
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0098 0.0298 0.0298
Entamoeba histolytica serine/threonine protein kinase, putative 0.0091 0.0275 0.0908
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0132 0.0488
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.0096 0.0096
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0038 0.0097 0.214
Onchocerca volvulus 0.0026 0.0058 0.036
Echinococcus multilocularis nmda type glutamate receptor 0.0052 0.0145 0.0145
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0068 0.0197 0.0193
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0037 0.0037
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0132 0.0126
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0018 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0207 0.0207
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0038 0.0097 0.214
Echinococcus granulosus multidrug resistance protein 1 0.0075 0.0221 0.0221
Schistosoma mansoni cpg binding protein 0.0029 0.0069 0.0069
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.007 0.007
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0054 0.0054
Plasmodium falciparum multidrug resistance-associated protein 1 0.0024 0.005 0.0184
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0083 0.0083
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.0207 0.0207
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0167 0.0161
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0024 0.005 0.1035
Brugia malayi MH2 domain containing protein 0.0364 0.118 0.118
Giardia lamblia Multidrug resistance-associated protein 1 0.0024 0.005 0.0546
Brugia malayi nuclear hormone receptor 0.0033 0.0083 0.0083
Schistosoma mansoni multidrug resistance protein 0.0075 0.0221 0.0221
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0022 0.0045 0.0045
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0075 0.0221 0.2359
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0911 1
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.004 0.0354
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.046 0.1498 0.1493
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.2589 0.2589
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0822 0.2698 0.2698
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0381 0.1236 0.1236
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0144 0.0144
Echinococcus multilocularis dna polymerase eta 0.0014 0.0018 0.0018
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0086 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0122 0.1259
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0075 0.0221 0.5072
Brugia malayi PXA domain containing protein 0.0019 0.0036 0.0036
Brugia malayi ABC transporter family protein 0.0024 0.005 0.005
Schistosoma mansoni smad 0.0025 0.0054 0.0054
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0024 0.005 0.1035
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0088 0.0088
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0085 0.0254 0.0254
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0036 0.0036
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0015 0.002 0.002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0035
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0024 0.005 0.0184
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0049 0.0133 0.0133
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0109 0.1112
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.0207 0.0207
Giardia lamblia Kinase, PLK 0.0091 0.0275 0.3022
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0058 0.0058
Echinococcus multilocularis cpg binding protein 0.0029 0.0069 0.0069
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.003 0.0072 0.0072
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0075 0.0221 0.0221
Schistosoma mansoni spingomyelin synthetase-related 0.0049 0.0133 0.0133
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.0207 0.0207
Echinococcus granulosus agrin 0.0037 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Brugia malayi MH2 domain containing protein 0.0025 0.0054 0.0054
Entamoeba histolytica hypothetical protein 0.0049 0.0133 0.0424
Loa Loa (eye worm) hypothetical protein 0.0071 0.0207 0.0207
Loa Loa (eye worm) Smad1 0.0025 0.0054 0.0054
Loa Loa (eye worm) ABC transporter 0.0024 0.005 0.005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0096 0.0096
Brugia malayi nuclear receptor NHR-67 0.0033 0.0083 0.0083
Echinococcus multilocularis multidrug resistance protein 1 0.0075 0.0221 0.0221
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0075 0.0221 0.2359
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.046 0.1498 0.1495
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0024 0.005 0.0044
Echinococcus granulosus leucyl aminopeptidase 0.0014 0.0017 0.0017
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0115 0.0352 0.8153
Toxoplasma gondii transporter, major facilitator family protein 0.0054 0.0151 0.0559
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0075 0.0221 0.2359
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0075 0.0221 0.2359
Plasmodium vivax multidrug resistance protein 1, putative 0.0075 0.0221 0.6082
Echinococcus granulosus dna polymerase eta 0.0014 0.0018 0.0018
Schistosoma mansoni rab6-interacting 0.0019 0.0035 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0528 0.1724 0.1724
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0104 0.01
Schistosoma mansoni carbonic anhydrase-related 0.0822 0.2698 0.2698
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.0207 0.1433
Echinococcus multilocularis RUN 0.0019 0.0035 0.0035
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.005 0.0459
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0083 0.0083
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0036 0.0036
Schistosoma mansoni smad1 5 8 and 0.0025 0.0054 0.0054
Brugia malayi nuclear receptor NHR-88 0.0071 0.0207 0.0207
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0038 0.0097 0.0849
Brugia malayi MH2 domain containing protein 0.0025 0.0054 0.0054
Toxoplasma gondii hypothetical protein 0.0822 0.2698 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0227 0.0227
Trichomonas vaginalis ABC transporter, putative 0.0075 0.0221 0.2359
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0091 0.0275 0.027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.0207 0.0207
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0182 0.0182
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0015 0.002 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0067 0.0067
Entamoeba histolytica P-glycoprotein-2, putative 0.0075 0.0221 0.0725
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0227 0.084
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0014 0.0017 0.0013
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0045 0.0045
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0006 0.0006
Entamoeba histolytica hypothetical membrane-spanning protein 0.0049 0.0133 0.0424

Activities

Activity type Activity value Assay description Source Reference
CD50 (functional) = 5.5 mg kg-1 Convulsant potency was determined by measuring the ability to produce seizures in mice ChEMBL. 1849999
CD50 (functional) = 5.5 mg kg-1 Convulsant potency was determined by measuring the ability to produce seizures in mice ChEMBL. 1849999
IC50 (binding) = 13 mM Binding affinity to picrotoxin site of Gamma-aminobutyric-acid receptor using [35S]-TBPS as radioligand ChEMBL. 1849999
IC50 (binding) = 13 mM Binding affinity to picrotoxin site of Gamma-aminobutyric-acid receptor using [35S]-TBPS as radioligand ChEMBL. 1849999

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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