Detailed information for compound 538145

Basic information

Technical information
  • TDR Targets ID: 538145
  • Name: 2-[[(2E)-2-(2-aminothiazol-4-yl)-2-methoxyimi no-acetyl]amino]-6-methoxycarbonyl-3-oxo-2,7- dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxyl ic acid
  • MW: 424.389 | Formula: C15H16N6O7S
  • H donors: 3 H acceptors: 6 LogP: -2.72 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CO/N=C(\c1csc(n1)N)/C(=O)NC1CN2N(C1=O)C(=C(C2)C(=O)OC)C(=O)O
  • InChi: 1S/C15H16N6O7S/c1-27-14(26)6-3-20-4-7(12(23)21(20)10(6)13(24)25)17-11(22)9(19-28-2)8-5-29-15(16)18-8/h5,7H,3-4H2,1-2H3,(H2,16,18)(H,17,22)(H,24,25)/b19-9+
  • InChiKey: LBQXXYPVUCVIOC-DJKKODMXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[[(2E)-2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-6-methoxycarbonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid
  • 2-[[(2E)-2-(2-azanyl-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-6-methoxycarbonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid
  • 2-[[(2E)-2-(2-aminothiazol-4-yl)-2-methyloximino-acetyl]amino]-6-carbomethoxy-3-keto-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid
  • 2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-methoxycarbonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid
  • LY 173013
  • 2-[[(2E)-2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-6-carbomethoxy-3-keto-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid
  • 2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-6-methoxycarbonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid
  • 126165-78-4
  • 1H,5H-Pyrazolo(1,2-a)pyrazole-2,3-dicarboxylic acid, 6-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-6,7-dihydro-5-oxo-, 2-methyl ester
  • LY-173013

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0036 0.0034 0.0032
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0095 0.035
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0015 0.0154
Brugia malayi hypothetical protein 0.002 0.0011 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0066 0.0078 0.0124
Brugia malayi MH1 domain containing protein 0.0016 0.0005 0.0004
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.015 0.0199 0.2306
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0016 0.0058
Giardia lamblia DINP protein human, muc B family 0.0097 0.0122 0.0449
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Echinococcus granulosus geminin 0.1079 0.154 0.4235
Trypanosoma brucei polo-like protein kinase 0.0189 0.0255 0.0932
Leishmania major DNA damage repair protein, putative 0.0028 0.0023 0.0084
Plasmodium vivax glutathione reductase, putative 0.0125 0.0163 0.0596
Onchocerca volvulus 0.0015 0.0003 0.0001
Loa Loa (eye worm) nuclear receptor NHR-67 0.005 0.0055 0.0362
Toxoplasma gondii heat shock protein 75, putative 0.0028 0.0022 0.008
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.002 0.0011 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.0116 0.0149 0.0548
Echinococcus multilocularis musashi 0.0171 0.0229 0.0368
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0059 0.0208
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0358 0.0499 0.2806
Schistosoma mansoni rab6-interacting 0.015 0.0198 0.0643
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0015 0.0154
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0056 0.0063 0.0422
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0023 0.0076
Schistosoma mansoni lamin 0.0171 0.0229 0.0742
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0142 0.0188 0.1048
Brugia malayi hypothetical protein 0.002 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.006
Plasmodium vivax DNA repair protein REV1, putative 0.0028 0.0023 0.0082
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Schistosoma mansoni hypothetical protein 0.0178 0.0238 0.0773
Loa Loa (eye worm) hypothetical protein 0.037 0.0517 0.3527
Schistosoma mansoni heat shock protein 0.0068 0.008 0.0259
Schistosoma mansoni lipoxygenase 0.0555 0.0783 0.2543
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0007 0.0018
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0119 0.0153 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0019 0.0095
Onchocerca volvulus 0.0091 0.0113 0.0111
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0023 0.0076
Onchocerca volvulus 0.002 0.0011 0.0009
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0003 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0043 0.0045 0.4577
Loa Loa (eye worm) hypothetical protein 0.0023 0.0016 0.0097
Plasmodium falciparum DNA repair protein REV1, putative 0.0028 0.0023 0.0082
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0015 0.0154
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0189 0.0255 0.0938
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Brugia malayi latrophilin 2 splice variant baaae 0.0178 0.0238 0.0326
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0107 0.0136 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Loa Loa (eye worm) hypothetical protein 0.0056 0.0063 0.0422
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0007 0.0024
Schistosoma mansoni nuclear receptor nhr-48 0.005 0.0055 0.0176
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Schistosoma mansoni DNA helicase recq5 0.0046 0.0048 0.0156
Schistosoma mansoni helicase 0.0065 0.0076 0.0245
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0192 0.026 0.1457
Brugia malayi bZIP transcription factor family protein 0.002 0.0011 0.0012
Onchocerca volvulus 0.005 0.0055 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Echinococcus multilocularis Tolloid protein 1 0.0014 0.0002 0.0002
Brugia malayi nuclear hormone receptor 0.0107 0.0136 0.0185
Brugia malayi hypothetical protein 0.005 0.0055 0.0073
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0046 0.0048 0.0132
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0021
Plasmodium falciparum DNA gyrase subunit B 0.0014 0.0002 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0377 0.0526 0.1446
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0417 0.0585 0.6815
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0101 0.0276
Toxoplasma gondii subtilisin SUB12 0.0015 0.0003 0.001
Brugia malayi hypothetical protein 0.002 0.0011 0.0012
Onchocerca volvulus 0.0015 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0033
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0091 0.0113 0.0366
Brugia malayi ecdysteroid receptor 0.0107 0.0136 0.0185
Loa Loa (eye worm) TOPoisomerase family member 0.0014 0.0002 0.0002
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0268 0.037 0.2076
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0014 0.0002 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0107 0.0136 0.044
Schistosoma mansoni coup transcription factor 0.0107 0.0136 0.044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0092
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0005 0.0007
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0042 0.0227
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0007
Brugia malayi hypothetical protein 0.0377 0.0526 0.0722
Echinococcus granulosus neuropeptide s receptor 0.0448 0.0629 0.1728
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.0234 0.0233
Toxoplasma gondii cathepsin CPL 0.0017 0.0007 0.0024
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0014 0.0002 0.0006
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.0153 0.1768
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.004
Loa Loa (eye worm) TK/ROR protein kinase 0.0081 0.0098 0.0661
Loa Loa (eye worm) trypsin family protein 0.002 0.0011 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.006 0.0214
Schistosoma mansoni transcription factor LCR-F1 0.0377 0.0526 0.1708
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0066 0.0078 0.0285
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Echinococcus multilocularis Smad4 0.0016 0.0005 0.0007
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0125 0.0163 0.1878
Loa Loa (eye worm) doublecortin family protein 0.015 0.0198 0.1346
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0417 0.0585 0.215
Onchocerca volvulus 0.002 0.0011 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0119 0.0153 0.0497
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Trypanosoma cruzi PHD-zinc-finger like domain containing protein, putative 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.006 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0071 0.0477
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0295 0.0408 0.475
Echinococcus multilocularis laminin 0.0014 0.0002 0.0002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0101 0.0162
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0005 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0232 0.0317 0.2162
Plasmodium falciparum thioredoxin reductase 0.0043 0.0045 0.0162
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0046 0.0048 0.0064
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0035
Schistosoma mansoni DNA topoisomerase II 0.0014 0.0002 0.0005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0043 0.0045 0.0164
Schistosoma mansoni zinc finger protein 0.0014 0.0002 0.0004
Echinococcus granulosus lamin 0.0171 0.0229 0.0628
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Toxoplasma gondii calcium binding egf domain-containing protein 0.0014 0.0002 0.0005
Leishmania major hypothetical protein, conserved 0.0081 0.0098 0.0362
Loa Loa (eye worm) hypothetical protein 0.0432 0.0606 0.4138
Trypanosoma brucei telomerase reverse transcriptase 0.1895 0.2718 1
Onchocerca volvulus 0.0017 0.0007 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0107 0.0136 0.0919
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0081 0.0098 0.036
Schistosoma mansoni RAR-like nuclear receptor 0.0107 0.0136 0.044
Echinococcus multilocularis survival motor neuron protein 1 0.1025 0.1462 0.2356
Schistosoma mansoni bromodomain containing protein 0.0014 0.0002 0.0004
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0028 0.0022 0.006
Schistosoma mansoni lamin 0.0171 0.0229 0.0742
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0033
Schistosoma mansoni hypothetical protein 0.0377 0.0526 0.1708
Onchocerca volvulus 0.0015 0.0003 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0358 0.0499 0.1835
Schistosoma mansoni survival motor neuron protein 0.0209 0.0284 0.0921
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0447 0.0627 0.2035
Echinococcus multilocularis X box binding protein 1 0.0624 0.0882 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0014 0.0002 0.0007
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.015 0.0199 0.2306
Echinococcus granulosus tissue type plasminogen activator 0.0081 0.0098 0.0269
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Schistosoma mansoni polycystin 1-related 0.015 0.0198 0.0643
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0202 0.0274 0.0751
Plasmodium vivax heat shock protein 90, putative 0.0028 0.0022 0.008
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Echinococcus granulosus protocadherin 11 0.002 0.0011 0.0028
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0032 0.0028 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0059 0.0215
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0142 0.0188 0.0688
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0015 0.0071
Onchocerca volvulus 0.0017 0.0007 0.0005
Schistosoma mansoni transcriptional factor nfil3/e4bp4 0.002 0.0011 0.0033
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0295 0.0408 0.15
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0095 0.0525
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0014 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0092 0.0506
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Echinococcus multilocularis neuropeptide s receptor 0.0448 0.0629 0.1012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0034 0.0219
Schistosoma mansoni intermediate filament proteins 0.0171 0.0229 0.0742
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0189 0.0255 0.0701
Echinococcus granulosus ecdysone induced protein 78C 0.0107 0.0136 0.0373
Brugia malayi isocitrate dehydrogenase 0.0066 0.0078 0.0104
Loa Loa (eye worm) cysteine protease 0.0017 0.0007 0.0036
Brugia malayi Thioredoxin reductase 0.0125 0.0163 0.0221
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Schistosoma mansoni cpg binding protein 0.021 0.0285 0.0923
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0016 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0092 0.0506
Leishmania major cathepsin L-like protease 0.0066 0.0077 0.0284
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0389 0.0544 0.0876
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.0005
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0051 0.0055 0.0196
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0083 0.095
Trypanosoma brucei Heat shock protein 83, putative 0.0068 0.008 0.0287
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Trichomonas vaginalis endoplasmin, putative 0.0042 0.0042 0.0227
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0015 0.0018
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0344 0.0479 0.5582
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0107 0.0136 0.0218
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0092
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0107 0.0136 0.0218
Schistosoma mansoni myst-related protein 0.0025 0.0018 0.0056
Brugia malayi hypothetical protein 0.0056 0.0063 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.0016 0.005
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0096 0.012 0.039
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0015 0.0018
Onchocerca volvulus 0.0015 0.0003 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0107 0.0136 0.044
Echinococcus granulosus lipoxygenase domain containing protein 0.015 0.0198 0.0544
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0016 0.0005 0.0013
Schistosoma mansoni cpg binding protein 0.0221 0.0302 0.0979
Schistosoma mansoni SET domain protein 0.0038 0.0036 0.0117
Loa Loa (eye worm) nuclear hormone receptor 0.005 0.0055 0.0362
Trypanosoma brucei chrX additional, unordered contigs 0.0028 0.0023 0.0076
Plasmodium vivax vivapain-2 0.0017 0.0007 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0055 0.0087
Brugia malayi Flap endonuclease-1 0.0051 0.0055 0.0074
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Schistosoma mansoni hypothetical protein 0.0594 0.084 0.2727
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0054 0.006 0.0218
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0091 0.0113 0.0153
Loa Loa (eye worm) endoplasmin 0.0068 0.008 0.0536
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0034 0.0091
Entamoeba histolytica cysteine protease, putative 0.0017 0.0007 0.0028
Brugia malayi mbt repeat family protein 0.0096 0.012 0.0163
Onchocerca volvulus 0.015 0.0198 0.0196
Brugia malayi nuclear receptor NHR-67 0.005 0.0055 0.0073
Echinococcus multilocularis geminin 0.1079 0.154 0.2481
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0054 0.006 0.0221
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0417 0.0585 0.215
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.002 0.0011 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0377 0.0526 0.0847
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0107 0.0136 0.0218
Schistosoma mansoni nuclear hormone receptor 0.0107 0.0136 0.044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Giardia lamblia Flap structure-specific endonuclease 0.0051 0.0055 0.0201
Schistosoma mansoni smad1 5 8 and 0.0016 0.0005 0.0014
Loa Loa (eye worm) intermediate filament protein 0.0171 0.0229 0.1555
Echinococcus multilocularis purine nucleoside phosphorylase 0.0344 0.0479 0.0772
Loa Loa (eye worm) hypothetical protein 0.0053 0.0059 0.0389
Giardia lamblia Telomerase catalytic subunit 0.1895 0.2718 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0107 0.0136 0.0218
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0024 0.0065
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Mycobacterium tuberculosis Probable reductase 0.0119 0.0153 0.1768
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0055 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0015 0.0056
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0005 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0191 0.0523
Treponema pallidum hypothetical protein 0.0295 0.0408 0.2293
Echinococcus multilocularis glycoprotein Antigen 5 0.002 0.0011 0.0017
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0119 0.0153 0.0557
Onchocerca volvulus 0.002 0.0011 0.0009
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0097 0.0122 0.1409
Echinococcus granulosus zinc finger protein 0.0014 0.0002 0.0004
Onchocerca volvulus 0.0015 0.0003 0.0001
Toxoplasma gondii microneme protein MIC4 0.0015 0.0003 0.001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0101 0.0136
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0107 0.0136 0.0919
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0051 0.0055 0.0203
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0191 0.0618
Toxoplasma gondii phosphorylase family protein 0.0142 0.0188 0.0688
Loa Loa (eye worm) ICD-1 protein 0.0076 0.0092 0.0615
Giardia lamblia DNA repair protein RAD52 0.0676 0.0959 0.3526
Loa Loa (eye worm) mbt repeat family protein 0.0096 0.012 0.0812
Plasmodium vivax flap endonuclease 1, putative 0.0051 0.0055 0.0201
Loa Loa (eye worm) transcription factor SMAD2 0.0232 0.0317 0.2162
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0095 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0051 0.0055 0.03
Echinococcus multilocularis purine nucleoside phosphorylase 0.0344 0.0479 0.0772
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0015 0.0154
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0003 0.001
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0011
Trichomonas vaginalis heat shock protein, putative 0.0054 0.006 0.0328
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0014 0.0002 0.0002
Leishmania major DNA polymerase kappa, putative 0.0028 0.0023 0.0084
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0023 0.0084
Echinococcus multilocularis purine nucleoside phosphorylase 0.0202 0.0274 0.044
Brugia malayi Hepatic leukemia factor 0.002 0.0011 0.0012
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0014 0.0002 0.0005
Schistosoma mansoni SET domain protein 0.0028 0.0022 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0107 0.0136 0.0185
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.002 0.0011 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.006 0.0214
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0389 0.0544 0.1495
Loa Loa (eye worm) bZIP transcription factor family protein 0.002 0.0011 0.006
Toxoplasma gondii RNA-directed DNA polymerase 0.1895 0.2718 1
Brugia malayi Steroid receptor seven-up type 2 0.0107 0.0136 0.0185
Loa Loa (eye worm) hypothetical protein 0.0111 0.0142 0.0959
Brugia malayi hypothetical protein 0.0056 0.0063 0.0085
Brugia malayi TAR-binding protein 0.0062 0.0071 0.0096
Echinococcus granulosus ccaat enhancer binding protein delta 0.002 0.0011 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0051 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0107 0.0136 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0107 0.0136 0.0185
Trypanosoma brucei trypanothione reductase 0.0125 0.0163 0.0591
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.008 0.0294
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0109 0.0139 0.0224
Loa Loa (eye worm) hypothetical protein 0.0056 0.0063 0.0422
Echinococcus multilocularis isocitrate dehydrogenase 0.0066 0.0078 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0063
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.004
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0043 0.0045 0.0071
Brugia malayi nuclear hormone receptor family member odr-7 0.005 0.0055 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0054 0.006 0.022
Toxoplasma gondii NAC domain-containing protein 0.0076 0.0092 0.0335
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0107 0.0136 0.044
Brugia malayi intermediate filament protein 0.0171 0.0229 0.0313
Giardia lamblia NADH oxidase lateral transfer candidate 0.0043 0.0045 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Entamoeba histolytica hypothetical protein 0.0377 0.0526 0.2959
Schistosoma mansoni bromodomain containing protein 0.0014 0.0002 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0191 0.026
Echinococcus multilocularis tissue type plasminogen activator 0.0081 0.0098 0.0158
Trypanosoma cruzi heat shock protein, putative 0.0028 0.0022 0.0082
Loa Loa (eye worm) hypothetical protein 0.0081 0.0098 0.0661
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0119 0.0153 0.0247
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0022 0.008
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0358 0.0499 0.3405
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0107 0.0136 0.0185
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0119 0.0153 0.0497
Loa Loa (eye worm) hypothetical protein 0.0662 0.0938 0.6412
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0295 0.0408 0.475
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0107 0.0136 0.044
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0107 0.0136 0.0373
Brugia malayi MTAP 0.0417 0.0585 0.0803
Onchocerca volvulus Serine\/threonine kinase homolog 0.0189 0.0255 0.0253
Loa Loa (eye worm) MBCTL1 0.0109 0.0139 0.0943
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0189 0.0255 0.041
Echinococcus multilocularis smad 0.0016 0.0005 0.0007
Brugia malayi Pre-SET motif family protein 0.0036 0.0034 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0095 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0014 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0023 0.0015 0.0052
Schistosoma mansoni hypothetical protein 0.0082 0.0101 0.0326
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Onchocerca volvulus 0.0015 0.0003 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0151 0.0554
Plasmodium falciparum thioredoxin reductase 0.0125 0.0163 0.0596
Leishmania major methylthioadenosine phosphorylase, putative 0.0417 0.0585 0.215
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0059 0.0214
Trichomonas vaginalis DNA polymerase eta, putative 0.0117 0.0151 0.084
Mycobacterium leprae probable uridine phosphorylase 0.0142 0.0188 0.2171
Leishmania major basic transcription factor 3a, putative 0.0076 0.0092 0.0337
Leishmania major heat shock protein, putative 0.0028 0.0022 0.0082
Treponema pallidum pfs protein (pfs) 0.0142 0.0188 0.1048
Brugia malayi ecdysone receptor 0.005 0.0055 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0107 0.0136 0.0185
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0082 0.0294
Toxoplasma gondii NADPH-glutathione reductase 0.0043 0.0045 0.0162
Onchocerca volvulus Huntingtin homolog 0.0662 0.0938 0.0936
Schistosoma mansoni methylthioadenosine phosphorylase 0.0417 0.0585 0.1898
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0358 0.0499 0.162
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0071 0.0231
Echinococcus granulosus Mastin 0.002 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0429 0.0601 0.4106
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0064 0.0352
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0015 0.0154
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Trypanosoma brucei uridine phosphorylase 0.0142 0.0188 0.0683
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0023 0.0084
Plasmodium falciparum LCCL domain-containing protein 0.015 0.0198 0.0728
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0358 0.0499 0.1835
Echinococcus multilocularis cpg binding protein 0.0221 0.0302 0.0486
Schistosoma mansoni purine nucleoside phosphorylase 0.0344 0.0479 0.1555
Mycobacterium ulcerans hypothetical protein 0.0028 0.0023 0.0243
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0117 0.0651
Plasmodium vivax telomerase reverse transcriptase, putative 0.1895 0.2718 1
Echinococcus granulosus survival motor neuron protein 1 0.1025 0.1462 0.4021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0107 0.0136 0.044
Echinococcus multilocularis lamin 0.0171 0.0229 0.0368
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0344 0.0479 0.0477
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0064 0.6705
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0295 0.0408 0.15
Schistosoma mansoni heat shock protein 0.0028 0.0022 0.0071
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0142 0.0188 0.069
Toxoplasma gondii exonuclease III APE 0.0057 0.0064 0.0235
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0043 0.0045 0.0157
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0069 0.0254
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0046 0.0048 0.0064
Leishmania major cathepsin L-like protease 0.0066 0.0077 0.0284
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Echinococcus multilocularis ubiquitin specific protease 41 0.0119 0.0153 0.0247
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.008 0.0294
Plasmodium falciparum endoplasmin, putative 0.0042 0.0042 0.0153
Onchocerca volvulus 0.0171 0.0229 0.0227
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Brugia malayi Telomerase reverse transcriptase 0.5043 0.7264 1
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0275 0.0379 0.441
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0054 0.006 0.068
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0191 0.0306
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0003 0.001
Echinococcus multilocularis RUN 0.015 0.0198 0.0319
Toxoplasma gondii microneme protein, putative 0.0015 0.0003 0.001
Brugia malayi steroid hormone receptor 0.0107 0.0136 0.0185
Loa Loa (eye worm) hypothetical protein 0.0082 0.0101 0.0677
Schistosoma mansoni heat shock protein 0.0068 0.008 0.0259
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0064 0.023
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0077 0.0284
Treponema pallidum uridine phosphorylase (udp) 0.0268 0.037 0.2076
Plasmodium vivax DNA topoisomerase II, putative 0.0014 0.0002 0.0006
Onchocerca volvulus 0.002 0.0011 0.0009
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0034 0.0122
Loa Loa (eye worm) hypothetical protein 0.0161 0.0215 0.1457
Brugia malayi orphan nuclear receptor NR2E1 0.005 0.0055 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0034 0.0108
Schistosoma mansoni hypothetical protein 0.1079 0.154 0.5001
Brugia malayi MH2 domain containing protein 0.0016 0.0005 0.0004
Echinococcus multilocularis transmembrane protease serine 3 0.002 0.0011 0.0017
Trypanosoma cruzi PHD-zinc-finger like domain containing protein, putative 0.0013 0 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0191 0.1293
Plasmodium falciparum basic transcription factor 3b, putative 0.0076 0.0092 0.0335
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0043 0.0045 0.0498
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0097 0.0122 0.045
Loa Loa (eye worm) CXXC zinc finger family protein 0.021 0.0285 0.1937
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0043 0.0045 0.0498
Echinococcus granulosus protocadherin 11 0.002 0.0011 0.0028
Trichomonas vaginalis helicase, putative 0.0047 0.0051 0.0274
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.015 0.0198 0.0643
Loa Loa (eye worm) hypothetical protein 0.0202 0.0274 0.1862
Trypanosoma brucei unspecified product 0.011 0.0141 0.0513
Brugia malayi Trypsin family protein 0.002 0.0011 0.0013
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0111 0.0142 0.0959
Toxoplasma gondii kringle domain-containing protein 0.0081 0.0098 0.036
Echinococcus multilocularis uridine phosphorylase 1 0.0142 0.0188 0.0302
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0043 0.0045 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0188 0.1048
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0007 0.0024
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0091 0.0113 0.031
Loa Loa (eye worm) BRM protein 0.0034 0.0031 0.0197
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0014 0.0002 0.0007
Trypanosoma cruzi transcription factor btf3, putative 0.0076 0.0092 0.0337
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0245 0.0336 0.1884
Loa Loa (eye worm) Smad1 0.0016 0.0005 0.0021
Plasmodium falciparum cysteine repeat modular protein 1 0.0081 0.0098 0.036
Leishmania major developmentally regulated phosphoprotein-like protein 0.0014 0.0002 0.0007
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0676 0.0959 0.5403
Echinococcus granulosus heat shock protein 90 0.0054 0.006 0.0164
Echinococcus granulosus thyroid hormone receptor alpha 0.005 0.0055 0.0149
Schistosoma mansoni smad 0.0016 0.0005 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0117 0.0651
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0043 0.0045 0.0157
Echinococcus granulosus Polycystic kidney disease protein 0.015 0.0198 0.0544
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.005 0.0055 0.0176
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0066 0.0078 0.0284
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0043 0.0045 0.0162
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0119 0.0153 0.0855
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Schistosoma mansoni cpg binding protein 0.0221 0.0302 0.0979
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0023 0.0084
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0066 0.0078 0.0285
Plasmodium falciparum telomerase reverse transcriptase 0.1895 0.2718 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0107 0.0136 0.044
Brugia malayi Doublecortin family protein 0.015 0.0198 0.0271
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Echinococcus granulosus RUN 0.015 0.0198 0.0544
Schistosoma mansoni hypothetical protein 0.0082 0.0101 0.0326
Loa Loa (eye worm) hypothetical protein 0.0429 0.0601 0.4106
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Brugia malayi nuclear receptor RXR 0.0056 0.0063 0.0085
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0026
Echinococcus granulosus enteropeptidase 0.002 0.0011 0.0029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0067 0.0079 0.0215
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0083 0.095
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Schistosoma mansoni hypothetical protein 0.1079 0.154 0.5001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0107 0.0136 0.044
Entamoeba histolytica transcription factor BTF3, putative 0.0076 0.0092 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0188 0.1048
Mycobacterium ulcerans DNA polymerase IV 0.0117 0.0151 0.1739
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0014 0.0002 0.0001
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0417 0.0585 0.0942
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Trichomonas vaginalis DNA helicase recq1, putative 0.0084 0.0104 0.0574
Brugia malayi cytoplasmic intermediate filament protein 0.0092 0.0114 0.0155
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0046 0.0048 0.0177
Loa Loa (eye worm) RNA binding protein 0.0062 0.0071 0.0477
Loa Loa (eye worm) thioredoxin reductase 0.0125 0.0163 0.1101
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Loa Loa (eye worm) hypothetical protein 0.0119 0.0153 0.1039
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0082 0.0294
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0358 0.0499 0.0685
Loa Loa (eye worm) hypothetical protein 0.0116 0.0149 0.1009
Echinococcus multilocularis Protein lozenge 0.0054 0.006 0.0095
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Trypanosoma cruzi DNA polymerase eta, putative 0.0053 0.0059 0.0216
Schistosoma mansoni flap endonuclease-1 0.0046 0.0048 0.0155
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0096 0.012 0.0119
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0107 0.0136 0.0373
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0107 0.0136 0.0218
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.124 0.1773 1
Trypanosoma brucei transcription factor BTF3, putative 0.0076 0.0092 0.033
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0003 0.001
Schistosoma mansoni hypothetical protein 0.0024 0.0016 0.0052
Echinococcus granulosus Tolloid protein 1 0.0014 0.0002 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Trypanosoma cruzi heat shock protein 90, putative 0.0068 0.008 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0092 0.0506
Plasmodium vivax heat shock protein 86, putative 0.0068 0.008 0.0293
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0095 0.026
Onchocerca volvulus 0.0096 0.012 0.0119
Giardia lamblia Pms1-like protein 0.0014 0.0002 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0059 0.0215
Loa Loa (eye worm) BRM protein 0.0042 0.0042 0.0276
Onchocerca volvulus 0.005 0.0055 0.0053
Giardia lamblia Sgs1 DNA helicase, putative 0.0046 0.0048 0.0177
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0071 0.0231
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0151 0.0554
Echinococcus multilocularis transcription factor Dp 1 0.0207 0.0281 0.0453
Schistosoma mansoni loxhd1 0.015 0.0198 0.0643
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0107 0.0136 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Schistosoma mansoni hypothetical protein 0.0023 0.0016 0.0049
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0066 0.0078 0.0124
Schistosoma mansoni nuclear receptor 0.005 0.0055 0.0176
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0043 0.0045 0.0162
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Loa Loa (eye worm) heat shock protein 90 0.0068 0.008 0.0536
Brugia malayi hypothetical protein 0.015 0.0198 0.0271
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0268 0.037 0.2076
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0107 0.0136 0.0373
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.006 0.0221
Loa Loa (eye worm) DR-78 0.005 0.0055 0.0362
Brugia malayi tailless protein 0.005 0.0055 0.0073
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0053 0.0058 0.0213
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Echinococcus granulosus tumor protein p63 0.253 0.3635 1
Schistosoma mansoni purine nucleoside phosphorylase 0.0344 0.0479 0.1555
Brugia malayi nuclear receptor NHR-88 0.0107 0.0136 0.0185
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0015 0.0154
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.005 0.0055 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Onchocerca volvulus 0.0017 0.0007 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0015 0.0074
Leishmania major trypanothione reductase 0.0125 0.0163 0.0598
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0255 0.0827
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0053 0.0059 0.0214
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0092 0.0114 0.077
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0059 0.0214
Onchocerca volvulus 0.037 0.0517 0.0515
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0119 0.0153 0.0421
Schistosoma mansoni inositol monophosphatase 0.0078 0.0095 0.0307
Trichomonas vaginalis DNA helicase recq, putative 0.0084 0.0104 0.0574
Schistosoma mansoni hypothetical protein 0.0624 0.0882 0.2865
Echinococcus multilocularis purine nucleoside phosphorylase 0.0344 0.0479 0.0772
Loa Loa (eye worm) isocitrate dehydrogenase 0.0066 0.0078 0.0519
Onchocerca volvulus 0.0245 0.0336 0.0334
Toxoplasma gondii calcium binding egf domain-containing protein 0.0014 0.0002 0.0005
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0101 0.0136
Entamoeba histolytica deoxycytidyl transferase, putative 0.0091 0.0113 0.0628
Brugia malayi RNA binding protein 0.0062 0.0071 0.0096
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0028 0.0022 0.0114
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0294 0.1999
Toxoplasma gondii heat shock protein HSP90 0.0068 0.008 0.0293
Loa Loa (eye worm) hypothetical protein 0.0056 0.0063 0.0422
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.008 0.0294
Brugia malayi Pre-SET motif family protein 0.0216 0.0294 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0095 0.0525
Giardia lamblia DNA damage repair protein 0.0028 0.0023 0.0082
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0255 0.035 0.0563
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0003 0.001
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0023 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0107 0.0136 0.0919
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0189 0.0255 0.1735
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0142 0.0188 0.069
Mycobacterium tuberculosis Conserved hypothetical protein 0.0091 0.0113 0.13
Trypanosoma brucei DNA polymerase IV, putative 0.011 0.0141 0.0513
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0107 0.0136 0.044
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.012 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Schistosoma mansoni smad1 5 8 and 0.0016 0.0005 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0063 0.0085
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0036
Echinococcus multilocularis muscleblind protein 1 0.03 0.0415 0.0669
Leishmania major DNA polymerase kappa, putative 0.0097 0.0122 0.045
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.006 0.0194
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0014 0.0002 0.0004
Schistosoma mansoni lipoxygenase 0.0285 0.0394 0.1278
Loa Loa (eye worm) hypothetical protein 0.0662 0.0938 0.6412
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Entamoeba histolytica hypothetical protein 0.0377 0.0526 0.2959
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.015 0.0199 0.2306
Brugia malayi Muscleblind-like protein 0.03 0.0415 0.0569
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0026
Echinococcus multilocularis flap endonuclease 1 0.0051 0.0055 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.005 0.0055 0.0149
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0055 0.0149
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Onchocerca volvulus 0.0015 0.0003 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.0107 0.0136 0.044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0034 0.0054
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0149 0.0203
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.0153 0.1768
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0107 0.0136 0.0919
Mycobacterium ulcerans hypothetical protein 0.0023 0.0015 0.0154
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0101 0.0677
Brugia malayi Protein kinase domain containing protein 0.0081 0.0098 0.0133
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0064 0.0352
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0043 0.0045 0.2295
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Brugia malayi Smad1 0.0016 0.0005 0.0004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0095 0.0348
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0046 0.0048 0.0132
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0003 0.001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Brugia malayi Nuclear hormone receptor E75 0.005 0.0055 0.0073
Brugia malayi MH2 domain containing protein 0.0232 0.0317 0.0435
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) flap endonuclease-1 0.0051 0.0055 0.0366
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0056 0.0063 0.0204
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0014 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0023 0.0084
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0046 0.0048 0.0077
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.004 0.0147
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0077 0.0284
Brugia malayi uridine phosphorylase family protein 0.0142 0.0188 0.0256
Loa Loa (eye worm) glutathione reductase 0.0125 0.0163 0.1101
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0014 0.0002 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0191 0.0306
Onchocerca volvulus Protein ultraspiracle homolog 0.0107 0.0136 0.0134
Brugia malayi Trypsin family protein 0.0111 0.0142 0.0193
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0014 0.0067
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0028 0.0023 0.0082
Brugia malayi BRM protein 0.0065 0.0076 0.0102
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.002 0.0011 0.0028
Echinococcus granulosus FTZ F1 alpha 0.0107 0.0136 0.0373
Chlamydia trachomatis AMP nucleosidase 0.0142 0.0188 1
Echinococcus multilocularis purine nucleoside phosphorylase 0.0344 0.0479 0.0772
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Mycobacterium ulcerans DNA polymerase IV 0.0117 0.0151 0.1739
Loa Loa (eye worm) hypothetical protein 0.015 0.0198 0.1346
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0014 0.0002 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0401 0.0561 0.2062
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0016 0.0005 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0064 0.0235
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0007 0.0005
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0417 0.0585 0.3992
Schistosoma mansoni egf-like domain protein 0.0014 0.0002 0.0005
Entamoeba histolytica hypothetical protein 0.0025 0.0018 0.0089
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0034 0.0054
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0071 0.0114
Loa Loa (eye worm) fibroinase 0.0017 0.0007 0.0036
Echinococcus granulosus mixed lineage leukemia protein mll 0.0054 0.006 0.0165
Loa Loa (eye worm) heat shock protein 75 0.0028 0.0022 0.014
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0095 0.0152
Echinococcus multilocularis microtubule associated protein 2 0.0668 0.0947 0.1526
Brugia malayi mbt repeat family protein 0.0096 0.012 0.0163
Entamoeba histolytica recQ family DNA helicase 0.0023 0.0016 0.0079
Brugia malayi heat shock protein 90 0.0068 0.008 0.0108
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0005 0.0021
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0003 0.001
Toxoplasma gondii Hsp90 domain-containing protein 0.0028 0.0022 0.008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0209 0.0284 0.0388
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0064 0.073
Echinococcus multilocularis dna polymerase kappa 0.0117 0.0151 0.0242
Echinococcus granulosus laminin 0.0014 0.0002 0.0004
Schistosoma mansoni nuclear receptor 0.005 0.0055 0.0176
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0417 0.0585 0.2145
Schistosoma mansoni kinase 0.0096 0.0121 0.0391
Loa Loa (eye worm) hypothetical protein 0.0082 0.0101 0.068
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0555 0.0783 0.2153
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Schistosoma mansoni blooms syndrome DNA helicase 0.0061 0.007 0.0225
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0043 0.0045 0.0164
Schistosoma mansoni nuclear hormone receptor 0.005 0.0055 0.0176
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0043 0.0045 0.0157
Echinococcus granulosus GPCR family 2 0.0082 0.0101 0.0276
Loa Loa (eye worm) hypothetical protein 0.0079 0.0097 0.0649
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0007 0.0024
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Brugia malayi Cell death specification protein 2 0.002 0.0011 0.0012
Brugia malayi hypothetical protein 0.0662 0.0938 0.1289
Echinococcus granulosus SAM and MBT domain containing protein 0.0096 0.012 0.033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0005 0.004
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0066 0.0078 0.0884
Entamoeba histolytica heat shock protein 90, putative 0.0068 0.008 0.0441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Brugia malayi Endoplasmin precursor 0.0068 0.008 0.0108
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0007 0.0018
Onchocerca volvulus 0.002 0.0011 0.0009
Echinococcus granulosus nuclear receptor nhr 48 0.005 0.0055 0.0149
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0107 0.0136 0.0218
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0043 0.0045 0.0162
Brugia malayi nuclear hormone receptor 0.005 0.0055 0.0073
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Echinococcus granulosus cathepsin l1 0.0017 0.0007 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0059 0.0214
Brugia malayi CXXC zinc finger family protein 0.021 0.0285 0.0389
Echinococcus multilocularis muscleblind protein 0.03 0.0415 0.0669
Echinococcus granulosus endoplasmin 0.0054 0.006 0.0164
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0026
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0015 0.0074
Giardia lamblia UPL-1 0.0142 0.0188 0.0688
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Toxoplasma gondii microneme protein MIC17B 0.0015 0.0003 0.001
Echinococcus granulosus polycomb protein SCMH1 0.0096 0.012 0.033
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.002 0.0011 0.0017
Echinococcus multilocularis enteropeptidase 0.002 0.0011 0.0017
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0268 0.037 0.2076
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0107 0.0136 0.0185
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0043 0.0045 0.0164
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.006
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0095 0.035
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0095 0.0525
Trichomonas vaginalis mercuric reductase, putative 0.0043 0.0045 0.0241
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0002 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.002 0.0011 0.0028
Leishmania major DNA topoisomerase ii 0.0014 0.0002 0.0007
Brugia malayi nuclear hormone receptor family member nhr-6 0.005 0.0055 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0606 0.0857 1
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Echinococcus granulosus intermediate filament protein 0.0171 0.0229 0.0628
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1895 0.2718 1
Schistosoma mansoni cellular tumor antigen P53 0.037 0.0517 0.1677
Leishmania major hypothetical protein, conserved 0.0013 0 0.0002
Leishmania major hypothetical protein, conserved 0.0053 0.0059 0.0215
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0071 0.0096
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0015 0.0154
Mycobacterium tuberculosis Probable oxidoreductase 0.015 0.0199 0.2306
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0007 0.0026
Echinococcus granulosus methylthioadenosine phosphorylase 0.0417 0.0585 0.1607
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0064 0.0352
Onchocerca volvulus 0.0107 0.0136 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0107 0.0136 0.0185
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0051 0.0274
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0056 0.0063 0.0173
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0051 0.0055 0.0203
Brugia malayi Kringle domain containing protein 0.0081 0.0098 0.0133
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0055 0.0053
Schistosoma mansoni par domain protein 0.002 0.0011 0.0033
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Treponema pallidum fructose-bisphosphate aldolase 0.124 0.1773 1
Echinococcus multilocularis heat shock protein 90 0.0054 0.006 0.0096
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0014 0.0002 0.0006
Echinococcus granulosus histone acetyltransferase MYST2 0.0109 0.0139 0.0383
Loa Loa (eye worm) hypothetical protein 0.03 0.0415 0.2832
Echinococcus multilocularis bloom syndrome protein 0.0084 0.0104 0.0166
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0344 0.0479 0.0657
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.002 0.0011 0.0016
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0142 0.0188 0.069
Loa Loa (eye worm) steroid hormone receptor 0.0107 0.0136 0.0919
Trypanosoma brucei heat shock protein, putative 0.0068 0.008 0.0287
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.002 0.0011 0.0028
Schistosoma mansoni lozenge 0.0054 0.006 0.0192
Schistosoma mansoni hypothetical protein 0.0081 0.0098 0.0318
Loa Loa (eye worm) hypothetical protein 0.0079 0.0097 0.0649
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0054 0.006 0.068
Echinococcus multilocularis neuropeptide receptor A26 0.0448 0.0629 0.1012
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0014 0.0002 0.0004
Brugia malayi Calcitonin receptor-like protein seb-1 0.026 0.0357 0.0489
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0051 0.0274
Echinococcus multilocularis zinc finger protein 0.0014 0.0002 0.0002
Echinococcus granulosus thioredoxin glutathione reductase 0.0125 0.0163 0.0446
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0358 0.0499 0.1371
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.002 0.0011 0.0016
Plasmodium falciparum DNA topoisomerase 2 0.0014 0.0002 0.0006
Leishmania major telomerase reverse transcriptase, putative 0.1895 0.2718 1
Schistosoma mansoni hypothetical protein 0.0082 0.0101 0.0326
Brugia malayi Inositol-1 0.0078 0.0095 0.0128
Onchocerca volvulus 0.0111 0.0142 0.014
Echinococcus multilocularis Polycystic kidney disease protein 0.015 0.0198 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0051 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0051 0.0274
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.124 0.1773 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0034 0.0108
Plasmodium vivax multidomain scavenger receptor, putative 0.015 0.0198 0.0728
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Brugia malayi hypothetical protein 0.0053 0.0059 0.0078
Trypanosoma cruzi heat shock protein 90, putative 0.0054 0.006 0.0221
Toxoplasma gondii Purine nucleoside phosphorylase 0.0268 0.037 0.1358
Echinococcus multilocularis fibrillin 1 0.0014 0.0002 0.0002
Toxoplasma gondii PAN/Apple domain-containing protein 0.0015 0.0003 0.001
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0056 0.0063 0.0101
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0095 0.1089
Schistosoma mansoni methylthioadenosine phosphorylase 0.0417 0.0585 0.1898
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0171 0.0229 0.1555
Trypanosoma brucei heat shock protein 84, putative 0.0028 0.0022 0.0074
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0358 0.0499 0.1829
Brugia malayi Isocitrate dehydrogenase 0.0066 0.0078 0.0104
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0043 0.0045 0.0162
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.012 0.039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Echinococcus granulosus ubiquitin specific protease 41 0.0119 0.0153 0.0421
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0555 0.0783 0.1261
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0007 0.0056
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0043 0.0045 0.0059
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0344 0.0479 0.5582
Loa Loa (eye worm) hypothetical protein 0.0175 0.0234 0.1594
Plasmodium vivax SET domain protein, putative 0.0036 0.0034 0.0122
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0046 0.0048 0.032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Brugia malayi F/Y-rich N-terminus family protein 0.0066 0.0078 0.0104
Brugia malayi hypothetical protein 0.1025 0.1462 0.2011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0014 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0107 0.0136 0.0185
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Plasmodium falciparum zinc finger protein, putative 0.0025 0.0018 0.0063
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.002 0.0011 0.0016
Brugia malayi N-terminal motif family protein 0.0175 0.0234 0.032
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0046 0.0048 0.0177
Loa Loa (eye worm) hypothetical protein 0.03 0.0415 0.2832
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0107 0.0136 0.0185
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0043 0.0045 0.0498
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0064 0.0176
Onchocerca volvulus 0.0171 0.0229 0.0227
Mycobacterium ulcerans hypothetical protein 0.002 0.0011 0.0106
Echinococcus multilocularis purine nucleoside phosphorylase 0.0344 0.0479 0.0772
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Plasmodium vivax DNA gyrase subunit B, putative 0.0014 0.0002 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0064 0.0237
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0015 0.0154
Echinococcus multilocularis dna polymerase eta 0.0116 0.0149 0.024
Onchocerca volvulus 0.0017 0.0007 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0015 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Schistosoma mansoni myelin transcription factor 1 myt1 0.0109 0.0139 0.0452
Schistosoma mansoni hypothetical protein 0.0082 0.0101 0.0326
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0015 0.0154
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0064 0.0237
Onchocerca volvulus 0.0015 0.0003 0.0001
Onchocerca volvulus 0.002 0.0011 0.0009
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0028 0.0022 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0005 0.0021
Plasmodium falciparum glutathione reductase 0.0125 0.0163 0.0596
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0043 0.0045 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0051 0.0274
Echinococcus granulosus neuropeptide receptor A26 0.0448 0.0629 0.1728
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0021
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0007 0.0259
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0046 0.0048 0.0177
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.002 0.0011 0.0016
Brugia malayi Intermediate filament tail domain containing protein 0.0171 0.0229 0.0313
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0071 0.0231
Onchocerca volvulus 0.0017 0.0007 0.0005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0064 0.0235
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.005 0.0055 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0064 0.0235
Echinococcus multilocularis Mastin 0.002 0.0011 0.0017
Loa Loa (eye worm) inositol-1 0.0078 0.0095 0.0639
Trypanosoma brucei heat shock protein 90, putative 0.0068 0.008 0.0287
Schistosoma mansoni hypothetical protein 0.2144 0.3078 1
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0014 0.0002 0.0006
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0107 0.0136 0.0373
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0003 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Echinococcus multilocularis FTZ F1 alpha 0.0107 0.0136 0.0218
Schistosoma mansoni microtubule-associated protein tau 0.0668 0.0947 0.3075
Toxoplasma gondii isocitrate dehydrogenase 0.0066 0.0078 0.0284
Echinococcus granulosus uridine phosphorylase 1 0.0142 0.0188 0.0515
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0344 0.0479 0.2694
Trypanosoma cruzi polo-like protein kinase, putative 0.0189 0.0255 0.0938
Brugia malayi serine/threonine-protein kinase plk-2 0.0189 0.0255 0.0349
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0432 0.0606 0.0832
Echinococcus multilocularis nuclear receptor nhr 48 0.005 0.0055 0.0087
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0119 0.0153 0.0564
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.0153 0.1768
Leishmania major cathepsin L-like protease 0.0066 0.0077 0.0284
Trypanosoma brucei unspecified product 0.0063 0.0072 0.0259
Entamoeba histolytica hypothetical protein 0.0377 0.0526 0.2959
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0045 0.0164
Entamoeba histolytica hypothetical protein 0.0377 0.0526 0.2959
Echinococcus granulosus flap endonuclease 1 0.0051 0.0055 0.0151
Trichomonas vaginalis glutathione reductase, putative 0.0043 0.0045 0.0241
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0066 0.0078 0.0284
Echinococcus multilocularis thioredoxin glutathione reductase 0.0125 0.0163 0.0261
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0054 0.006 0.0096
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Echinococcus granulosus glycoprotein Antigen 5 0.002 0.0011 0.0029
Plasmodium vivax vivapain-2 0.0017 0.0007 0.0024
Onchocerca volvulus 0.021 0.0285 0.0283
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0015 0.0056
Onchocerca volvulus 0.0019 0.0009 0.0007
Entamoeba histolytica serine/threonine protein kinase, putative 0.0189 0.0255 0.1429
Schistosoma mansoni terminal deoxycytidyl transferase 0.0091 0.0113 0.0366
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0077 0.0284
Trichomonas vaginalis DNA helicase recq, putative 0.0054 0.006 0.0327
Treponema pallidum heat shock protein 90 0.0054 0.006 0.0328
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0107 0.0136 0.0373
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Brugia malayi Bloom's syndrome protein homolog 0.0084 0.0104 0.014
Entamoeba histolytica hypothetical protein 0.0076 0.0092 0.0506
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0055 0.0149
Trichomonas vaginalis heat shock protein, putative 0.0054 0.006 0.0328
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0344 0.0479 0.1761
Schistosoma mansoni DNA polymerase IV / kappa 0.0028 0.0023 0.0072
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0032 0.0116
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Brugia malayi MH1 domain containing protein 0.0016 0.0005 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0151 0.0554
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0016 0.0057
Trypanosoma cruzi ISWI complex protein 0.0022 0.0014 0.0051
Toxoplasma gondii microneme protein MIC17C 0.0015 0.0003 0.001
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0606 0.0857 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0015 0.0154
Toxoplasma gondii DNA topoisomerase 2, putative 0.0014 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Onchocerca volvulus 0.002 0.0011 0.0009
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0255 0.035 0.096
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0142 0.0188 0.2171
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Toxoplasma gondii hypothetical protein 0.0015 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Schistosoma mansoni DNA polymerase eta 0.0116 0.0149 0.0483
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0038 0.0036 0.0099
Loa Loa (eye worm) pigment dispersing factor receptor c 0.026 0.0357 0.2433
Entamoeba histolytica hypothetical protein 0.002 0.0011 0.0048
Brugia malayi Trypsin family protein 0.002 0.0011 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Onchocerca volvulus 0.0017 0.0007 0.0005
Giardia lamblia Heat shock protein HSP 90-alpha 0.0054 0.006 0.0219
Onchocerca volvulus 0.0081 0.0098 0.0096
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0119 0.0153 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.002 0.0011 0.0029
Onchocerca volvulus 0.0015 0.0003 0.0001
Echinococcus multilocularis histone acetyltransferase MYST2 0.0109 0.0139 0.0224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0051 0.0274
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0054 0.006 0.0096
Brugia malayi Trypsin family protein 0.002 0.0011 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0066 0.0078 0.0285
Echinococcus multilocularis tumor protein p63 0.253 0.3635 0.5859
Trichomonas vaginalis heat shock protein, putative 0.0054 0.006 0.0328
Leishmania major DNA polymerase eta, putative 0.0116 0.0149 0.0548
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0007 0.0056
Onchocerca volvulus 0.0017 0.0007 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0077 0.0284
Echinococcus multilocularis global transcription activator snf2l2 0.0065 0.0076 0.0122
Brugia malayi glutathione reductase 0.0125 0.0163 0.0221
Brugia malayi Nuclear hormone receptor E75 0.005 0.0055 0.0073
Trypanosoma brucei ISWI complex protein 0.0022 0.0014 0.0043
Entamoeba histolytica hypothetical protein 0.0142 0.0188 0.1048
Loa Loa (eye worm) hypothetical protein 0.0096 0.012 0.0812
Loa Loa (eye worm) nuclear receptor nhr-7B 0.005 0.0055 0.0362
Trypanosoma cruzi trypanothione reductase, putative 0.0125 0.0163 0.0598
Trypanosoma cruzi transcription factor btf3, putative 0.0076 0.0092 0.0337
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0067 0.0079 0.0126
Brugia malayi hypothetical protein 0.002 0.0011 0.0012
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Leishmania major mitochondrial DNA topoisomerase II 0.0014 0.0002 0.0007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0043 0.0045 0.0164
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0011
Brugia malayi Trypsin-like protease protein 5 0.002 0.0011 0.0013
Echinococcus granulosus Smad4 0.0016 0.0005 0.0012
Echinococcus multilocularis GPCR, family 2 0.0082 0.0101 0.0162
Schistosoma mansoni transcription factor btf3 0.0076 0.0092 0.0296
Echinococcus multilocularis lamin dm0 0.0171 0.0229 0.0368
Plasmodium vivax heat shock protein, putative 0.0028 0.0022 0.008
Schistosoma mansoni zinc finger protein 0.005 0.0055 0.0176
Echinococcus multilocularis purine nucleoside phosphorylase 0.0344 0.0479 0.0772
Echinococcus multilocularis SAM and MBT domain containing protein 0.0096 0.012 0.0193
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0054 0.006 0.0213
Loa Loa (eye worm) histone methyltransferase 0.0067 0.0079 0.0527
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0358 0.0499 0.0803
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.005 0.0055 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Echinococcus granulosus microtubule associated protein 2 0.0668 0.0947 0.2604
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni pyruvate dehydrogenase 0.0014 0.0002 0.0005
Toxoplasma gondii phosphorylase family protein 0.0142 0.0188 0.0688
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Toxoplasma gondii microneme protein MIC17A 0.0015 0.0003 0.001
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Loa Loa (eye worm) hypothetical protein 0.0168 0.0224 0.1524
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0066 0.0078 0.0124
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.002 0.0011 0.0016
Toxoplasma gondii hypothetical protein 0.0015 0.0003 0.001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0043 0.0045 0.4577
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Loa Loa (eye worm) hypothetical protein 0.0107 0.0136 0.0919
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0098 0.0362
Treponema pallidum NADH oxidase 0.0043 0.0045 0.0241
Schistosoma mansoni endoplasmin 0.0068 0.008 0.0259
Trypanosoma brucei unspecified product 0.0063 0.0072 0.0259
Schistosoma mansoni myst-related protein 0.0025 0.0018 0.0056
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0015 0.0056
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0034
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0142 0.0459
Echinococcus granulosus transcription factor Dp 1 0.0207 0.0281 0.0772
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0107 0.0136 0.0373
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0005 0.0014
Echinococcus granulosus global transcription activator snf2l2 0.0065 0.0076 0.0208
Loa Loa (eye worm) hypothetical protein 0.015 0.0198 0.1346
Echinococcus granulosus transcription factor btf3 0.0076 0.0092 0.0251
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0082 0.0101 0.0162
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4309 0.6204 1
Loa Loa (eye worm) uridine phosphorylase 0.0142 0.0188 0.1273
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0092
Schistosoma mansoni endoplasmin 0.0068 0.008 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.002 0.0011 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0051 0.0274
Brugia malayi SET domain containing protein 0.0019 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0048 0.032
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0268 0.037 0.2076
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0066 0.0078 0.0251
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0091 0.0113 0.0182
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0066 0.0078 0.0124
Echinococcus granulosus muscleblind protein 0.03 0.0415 0.1141
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0028 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Giardia lamblia Fructose-bisphosphate aldolase 0.124 0.1773 0.6521
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0071 0.0231
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0014 0.0002 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0055 0.0149
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0026
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0091 0.0113 0.0763
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.0151 0.0547
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0038 0.0036 0.0058
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Echinococcus multilocularis endoplasmin 0.0054 0.006 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Echinococcus multilocularis purine nucleoside phosphorylase 0.0202 0.0274 0.044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0043 0.0045 0.0498
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0055 0.0087
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.005 0.0055 0.0087
Echinococcus multilocularis protocadherin 11 0.002 0.0011 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0034 0.0108
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0107 0.0136 0.0919
Echinococcus granulosus lamin dm0 0.0171 0.0229 0.0628
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Brugia malayi Hsp90 protein 0.0028 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0191 0.0618
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0064 0.0352
Echinococcus granulosus tar DNA binding protein 0.0062 0.0071 0.0195
Echinococcus granulosus bloom syndrome protein 0.0084 0.0104 0.0284
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0028
Giardia lamblia Hypothetical protein 0.002 0.0011 0.0037
Schistosoma mansoni methylthioadenosine phosphorylase 0.0142 0.0188 0.0608
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Brugia malayi Cell death specification protein 2 0.002 0.0011 0.0012
Leishmania major DNA polymerase eta, putative 0.0053 0.0059 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0034 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Plasmodium falciparum heat shock protein 90 0.0068 0.008 0.0293
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0268 0.037 0.1358
Brugia malayi hypothetical protein 0.0429 0.0601 0.0826
Loa Loa (eye worm) hypothetical protein 0.0109 0.0139 0.0943
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0035
Schistosoma mansoni Smad4 0.0016 0.0005 0.0014
Echinococcus granulosus heat shock protein 0.0068 0.008 0.0219
Loa Loa (eye worm) hypothetical protein 0.005 0.0055 0.0362
Mycobacterium tuberculosis Hypothetical protein 0.0142 0.0188 0.2171
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0344 0.0479 0.5582
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Echinococcus multilocularis dnaJ subfamily B 0.2144 0.3078 0.4961
Schistosoma mansoni rab6-interacting 0.015 0.0198 0.0643
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0295 0.0408 0.475
Brugia malayi nuclear receptor RXR 0.005 0.0055 0.0073
Plasmodium falciparum glutathione reductase 0.0043 0.0045 0.0162
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0119 0.0153 0.0563
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Toxoplasma gondii thioredoxin reductase 0.0125 0.0163 0.0596
Brugia malayi polk-prov protein 0.0054 0.006 0.0081
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0043 0.0045 0.0143
Trypanosoma cruzi Heat shock protein 83, putative 0.0068 0.008 0.0294
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0095 0.0525
Mycobacterium ulcerans heat shock protein 90 0.0054 0.006 0.068
Entamoeba histolytica hypothetical protein 0.0192 0.026 0.1457
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0063 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0119 0.0153 0.0855
Schistosoma mansoni hypothetical protein 0.0209 0.0284 0.0921
Giardia lamblia Kinase, PLK 0.0189 0.0255 0.0937
Giardia lamblia Heat shock protein HSP 90-alpha 0.0068 0.008 0.0293
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0035
Brugia malayi hypothetical protein 0.005 0.0055 0.0073
Entamoeba histolytica heat shock protein 90, putative 0.0068 0.008 0.0441
Trichomonas vaginalis hypothetical protein 0.0025 0.0019 0.0095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0015 0.0074
Echinococcus granulosus lipoxygenase domain containing protein 0.015 0.0198 0.0544
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0142 0.0459
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0191 0.0523
Schistosoma mansoni DNA helicase recq1 0.0046 0.0048 0.0156
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0029 0.0091
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0007 0.0036
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0064 0.073
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0109 0.0139 0.019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0107 0.0136 0.0134
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0606 0.0857 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0107 0.0136 0.0185
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0063 0.0085
Echinococcus multilocularis lipoxygenase domain containing protein 0.015 0.0198 0.0319
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0119 0.0153 0.0855
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0268 0.037 0.2076
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0054 0.006 0.0164
Trypanosoma cruzi DNA topoisomerase II, putative 0.0014 0.0002 0.0007
Echinococcus granulosus dnaJ subfamily B 0.2144 0.3078 0.8468
Brugia malayi photoreceptor-specific nuclear receptor 0.0107 0.0136 0.0185
Echinococcus granulosus heat shock protein 90 0.0068 0.008 0.0219
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0119 0.0153 0.0209
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0066 0.0078 0.0278
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.0028
Echinococcus granulosus dna polymerase eta 0.0116 0.0149 0.0409
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Plasmodium vivax endoplasmin, putative 0.0068 0.008 0.0293
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0007 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0151 0.0554
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0022 0.008
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Brugia malayi Nuclear hormone receptor-like 1 0.0107 0.0136 0.0185
Plasmodium falciparum flap endonuclease 1 0.0051 0.0055 0.0201
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0014 0.0002 0.0007
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.015 0.0198 0.0319
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0014 0.0002 0.0002
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0016 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Onchocerca volvulus Bile acid receptor homolog 0.0107 0.0136 0.0134
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.002 0.0011 0.0034
Echinococcus granulosus smad 0.0016 0.0005 0.0012
Loa Loa (eye worm) RecQ helicase 0.0084 0.0104 0.0697
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0063
Plasmodium vivax thioredoxin reductase, putative 0.0125 0.0163 0.0596
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.0153 0.1768
Loa Loa (eye worm) cell death specification protein 2 0.002 0.0011 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0028
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0066 0.0078 0.0212
Trypanosoma brucei heat shock protein 90, putative 0.0068 0.008 0.0287
Brugia malayi PAN domain containing protein 0.0015 0.0003 0.0002
Loa Loa (eye worm) ctsf protein 0.0017 0.0007 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0255 0.1429
Brugia malayi conserved hypotetical protein 0.005 0.0055 0.0073
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0005 0.0012
Echinococcus granulosus cpg binding protein 0.0221 0.0302 0.0829
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0032 0.0028 0.0036
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0119 0.0153 0.0421
Trypanosoma cruzi DNA topoisomerase II, putative 0.0014 0.0002 0.0007
Leishmania major nucleoside phosphorylase-like protein 0.0142 0.0188 0.069
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.002 0.0011 0.0034
Plasmodium vivax basic transcription factor 3b, putative 0.0076 0.0092 0.0335
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.002 0.0011 0.0013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0064 0.0429
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0064 0.0237
Brugia malayi Cell death specification protein 2 0.002 0.0011 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0054 0.006 0.0165
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0064 0.0086
Echinococcus granulosus dna polymerase kappa 0.0117 0.0151 0.0413
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0057 0.0209
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0007 0.0023
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0076 0.0092 0.0337
Echinococcus multilocularis heat shock protein 90 0.0068 0.008 0.0128
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0001
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0142 0.0188 0.0688
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0014 0.0002 0.0001
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.002 0.0011 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0107 0.0136 0.0919
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0022 0.0114
Toxoplasma gondii isocitrate dehydrogenase 0.0066 0.0078 0.0284
Schistosoma mansoni nuclear hormone receptor 0.005 0.0055 0.0176
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0007
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0358 0.0499 0.1835
Onchocerca volvulus Huntingtin homolog 0.0662 0.0938 0.0936
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Echinococcus granulosus transmembrane protease serine 3 0.002 0.0011 0.0029
Echinococcus multilocularis protocadherin 11 0.002 0.0011 0.0016
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0003 0.001
Schistosoma mansoni uridine phosphorylase 0.0142 0.0188 0.0608
Leishmania major hypothetical protein, conserved 0.0013 0 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0082 0.0101 0.0277
Schistosoma mansoni smad1 5 8 and 0.0016 0.0005 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0142 0.0188 0.2171
Echinococcus multilocularis thyroid hormone receptor alpha 0.0107 0.0136 0.0218
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Schistosoma mansoni ap endonuclease 0.0057 0.0064 0.0208
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0117 0.0151 0.084
Loa Loa (eye worm) runx1 0.0054 0.006 0.0397
Onchocerca volvulus 0.002 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0063
Onchocerca volvulus 0.0209 0.0284 0.0282
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0119 0.0153 0.0564
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0036
Entamoeba histolytica recQ family helicase, putative 0.0054 0.006 0.0327
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0095 0.035
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0046 0.0048 0.0077
Trypanosoma cruzi polo-like protein kinase, putative 0.0189 0.0255 0.0938
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.0153 0.1768
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0122 0.0443
Brugia malayi hypothetical protein 0.015 0.0198 0.0271
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0064 0.0103
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0054 0.006 0.6244
Echinococcus multilocularis heat shock protein 0.0068 0.008 0.0128
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0055 0.0053
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0043 0.0045 0.0121
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1895 0.2718 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.006
Schistosoma mansoni uridine phosphorylase 0.0142 0.0188 0.0608
Loa Loa (eye worm) hypothetical protein 0.0171 0.0229 0.1555
Brugia malayi hypothetical protein 0.0034 0.0031 0.0041
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.0153 0.1768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.124 0.1773 1
Brugia malayi MH2 domain containing protein 0.0016 0.0005 0.0004
Plasmodium falciparum purine nucleoside phosphorylase 0.0268 0.037 0.1358
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0109 0.0139 0.0383
Schistosoma mansoni inositol monophosphatase 0.0078 0.0095 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0107 0.0136 0.0185
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0056 0.0063 0.0422
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0071 0.0477
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Onchocerca volvulus 0.0015 0.0003 0.0001
Onchocerca volvulus 0.0429 0.0601 0.06
Trypanosoma brucei DNA polymerase eta, putative 0.0116 0.0149 0.0542
Leishmania major heat shock protein 83-1 0.0068 0.008 0.0294
Brugia malayi beta-NAC-like protein 0.0076 0.0092 0.0124
Onchocerca volvulus 0.0023 0.0015 0.0013
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0015 0.0003 0.001
Trichomonas vaginalis heat shock protein, putative 0.0068 0.008 0.0441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0028
Loa Loa (eye worm) hypothetical protein 0.1025 0.1462 1
Entamoeba histolytica Flap nuclease, putative 0.0051 0.0055 0.03
Toxoplasma gondii heat shock protein 90, putative 0.0068 0.008 0.0293
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0054 0.006 0.022
Schistosoma mansoni thyrotroph embryonic factor related 0.002 0.0011 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0151 0.0547
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0107 0.0136 0.0373
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0045 0.0164
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.0151 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0082 0.0294
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0107 0.0136 0.0919
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0077 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0119 0.0153 0.0855
Echinococcus multilocularis transcription factor btf3 0.0076 0.0092 0.0147
Schistosoma mansoni cercarial elastase (S01 family) 0.002 0.0011 0.0034
Brugia malayi nuclear receptor NHR-88 0.005 0.0055 0.0073
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0026
Echinococcus granulosus purine nucleoside phosphorylase 0.0344 0.0479 0.1317
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0023 0.0076
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0066 0.0078 0.0278
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0051 0.0274
Schistosoma mansoni ap endonuclease 0.0057 0.0064 0.0208
Echinococcus multilocularis polycomb protein SCMH1 0.0096 0.012 0.0193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0191 0.0618
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0142 0.0188 0.1048
Treponema pallidum ATP-dependent DNA helicase 0.0023 0.0016 0.0079
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0059 0.0214
Echinococcus granulosus X box binding protein 1 0.0624 0.0882 0.2426
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0142 0.0188 0.2171
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0019 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0107 0.0136 0.0185
Onchocerca volvulus 0.002 0.0011 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0071 0.0231
Giardia lamblia Grp94/Hsp90 0.0054 0.006 0.0219
Onchocerca volvulus 0.0015 0.0003 0.0001
Onchocerca volvulus 0.015 0.0198 0.0196
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.002 0.0011 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0107 0.0136 0.044
Loa Loa (eye worm) hypothetical protein 0.0178 0.0238 0.162
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0051 0.0055 0.0201
Loa Loa (eye worm) hypothetical protein 0.0056 0.0063 0.0422

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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