Detailed information for compound 674694

Basic information

Technical information
  • TDR Targets ID: 674694
  • Name: 1-(1,3-benzodioxol-5-ylmethyl)-3-(4-fluorophe nyl)urea
  • MW: 288.274 | Formula: C15H13FN2O3
  • H donors: 2 H acceptors: 1 LogP: 2.33 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)F)NCc1ccc2c(c1)OCO2
  • InChi: 1S/C15H13FN2O3/c16-11-2-4-12(5-3-11)18-15(19)17-8-10-1-6-13-14(7-10)21-9-20-13/h1-7H,8-9H2,(H2,17,18,19)
  • InChiKey: OVDFVDLGCJKWCF-UHFFFAOYSA-N  


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Synonyms

  • 1-Benzo[1,3]dioxol-5-ylmethyl-3-(4-fluoro-phenyl)-urea
  • BAS 05338708
  • ZINC00413870

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0128 0.0859 0.1552
Loa Loa (eye worm) hypothetical protein 0.011 0.0724 0.1306
Echinococcus multilocularis expressed protein 0.0033 0.0148 0.014
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0018 0.0039 0.0433
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0095 0.0086
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0146 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0089
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Entamoeba histolytica presenilin 1 peptidase, putative 0.0198 0.1387 0.2767
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0302 0.0606
Brugia malayi hypothetical protein 0.0019 0.0049 0.0073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Trichomonas vaginalis hypothetical protein 0.0022 0.0071 0.0142
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0015 0.0014 0.0005
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0558 0.055
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0365 0.065
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Plasmodium vivax vivapain-2 0.0016 0.0027 0.049
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0029 0.0121 0.0113
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0131 0.0123
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0052 0.0293 0.0284
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0142 0.1918
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0174 0.0332
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0018
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0052 0.0291 0.1343
Entamoeba histolytica protein kinase, putative 0.0014 0.0009 0.000000054723
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0045 0.0036
Schistosoma mansoni cell adhesion molecule 0.0014 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0431 0.3124 0.5688
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0042 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0018
Onchocerca volvulus 0.011 0.0724 0.1361
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0166 0.0332
Echinococcus multilocularis Immunoglobulin 0.0025 0.0095 0.0087
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0114
Loa Loa (eye worm) hypothetical protein 0.0052 0.0291 0.0515
Schistosoma mansoni peroxidasin 0.0019 0.0043 0.0035
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0056 0.0048
Schistosoma mansoni lamin 0.0026 0.0101 0.0093
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0071 0.0062
Schistosoma mansoni gamma-secretase subunit aph-1 0.0473 0.3438 0.3432
Brugia malayi Pleckstrin Homology Domain 0.0023 0.0076 0.0122
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0018 0.0143
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0168 0.1157 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus multilocularis activin receptor type 0.0018 0.0039 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0193 0.0338
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0072
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0232 0.0448
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) animal heme peroxidase 0.0014 0.0012 0.0007
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0045 0.0036
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0015 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0082 0.0163
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0232 0.0448
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0049 0.004
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0064 0.0384 0.0754
Brugia malayi Presenilin spe-4 0.007 0.0424 0.0759
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0121 0.0205
Schistosoma mansoni hypothetical protein 0.0018 0.0042 0.0033
Echinococcus granulosus Chromo domain 0.0022 0.0071 0.0062
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0075 0.0066
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.033
Entamoeba histolytica protein kinase, putative 0.0014 0.001 0.0004
Echinococcus multilocularis epidermal growth factor receptor 0.0167 0.1152 0.1144
Schistosoma mansoni protein kinase C mu 0.0023 0.0076 0.0067
Leishmania major cathepsin L-like protease 0.0016 0.0027 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0087
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0018 0.002
Schistosoma mansoni rab6-interacting 0.0019 0.0049 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0748 0.5486 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0232 0.0448
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi RhoGEF domain containing protein 0.0023 0.0076 0.0122
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0178 0.0924
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0027 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Loa Loa (eye worm) hypothetical protein 0.0039 0.0193 0.0338
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0075 0.0066
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0198 0.1387 0.2767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0081 0.0163
Echinococcus granulosus c src tyrosine kinase 0.0024 0.0081 0.0072
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0014 0.0009 0.0017
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0293 0.0284
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Echinococcus granulosus basement membrane specific heparan sulfate 0.0018 0.0042 0.0033
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0174 0.0166
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0027 0.0106 0.0177
Echinococcus granulosus death domain containing protein 0.0014 0.001 0.0001
Echinococcus multilocularis raf serine:threonine protein kinase 0.0665 0.4868 0.4863
Onchocerca volvulus 0.0015 0.0018 0.0019
Trypanosoma cruzi polo-like protein kinase, putative 0.0681 0.499 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0024 0.0081 0.0072
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0232 0.0408
Loa Loa (eye worm) hypothetical protein 0.0039 0.0193 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus multilocularis tyrosine protein kinase HCK 0.0042 0.022 0.0212
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0198 0.1387 0.2767
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0168 0.1157 0.6098
Toxoplasma gondii hypothetical protein 0.0056 0.0324 0.452
Onchocerca volvulus 0.0014 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0087
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0115 0.0195
Echinococcus multilocularis c src tyrosine kinase 0.0024 0.0081 0.0072
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0174 0.0302
Brugia malayi Cathepsin L-like precursor 0.0016 0.0027 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0287 0.2047 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.012 0.08 0.0793
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0167 0.1152 0.1144
Brugia malayi RhoGAP domain containing protein 0.0029 0.0121 0.0206
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0149 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0014 0.001
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0688 0.5042 0.5038
Brugia malayi protein kinase C II. 0.0027 0.0106 0.0177
Onchocerca volvulus 0.0016 0.0027 0.0035
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0114 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0494 0.0991
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0046 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0066
Echinococcus granulosus Rac GTPase activating protein 1 0.0023 0.0076 0.0067
Schistosoma mansoni titin 0.0014 0.0012 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0027 0.049
Echinococcus granulosus nicalin 0.0036 0.0171 0.0162
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0029 0.0121 0.0113
Onchocerca volvulus 0.0016 0.0027 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Schistosoma mansoni cell adhesion molecule 0.0033 0.0149 0.014
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.002 0.0054 0.0046
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0014 0.0009 0.000000049764
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0076 0.0122
Echinococcus multilocularis Chromo domain 0.0022 0.0071 0.0062
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0014 0.0012 0.0004
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0027 0.0035
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0045 0.0036
Schistosoma mansoni septate junction protein 0.0018 0.0042 0.0033
Schistosoma mansoni hypothetical protein 0.0018 0.0042 0.0033
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0173 0.0165
Schistosoma mansoni basigin related 0.0018 0.0042 0.0033
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0018 0.0039 0.003
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0046 0.0068
Schistosoma mansoni tyrosine kinase 0.0052 0.0293 0.0284
Echinococcus multilocularis protoporphyrinogen oxidase 0.002 0.0056 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0049 0.0073
Brugia malayi Cathepsin L-like precursor 0.0016 0.0027 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0042 0.0061
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.0095 0.0086
Echinococcus multilocularis hemicentin 1 0.0033 0.0149 0.014
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0025 0.0095 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0106 0.0097
Brugia malayi Peroxidasin 0.0033 0.015 0.0259
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0042 0.0062
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.0076 0.0067
Loa Loa (eye worm) TK/EGFR protein kinase 0.03 0.2147 0.3904
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0142 0.0268
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.035 0.1636
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0024 0.0081 0.0072
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0302 0.0294
Echinococcus granulosus protein kinase c iota type 0.0027 0.0106 0.0097
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1636 0.3278
Echinococcus granulosus tyrosine protein kinase Srms 0.002 0.0054 0.0046
Echinococcus granulosus tyrosine protein kinase Src64B 0.0052 0.0293 0.0284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Brugia malayi Death domain containing protein 0.0014 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0066
Brugia malayi Presenilin family protein 0.0198 0.1387 0.2516
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0061
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0131 0.0123
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0027 0.0018
Loa Loa (eye worm) TK protein kinase 0.0028 0.0115 0.0195
Echinococcus multilocularis presenilin enhancer 2 0.0186 0.1296 0.1288
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0056 0.0282
Echinococcus granulosus tyrosine protein kinase HCK 0.0042 0.022 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Furin-like cysteine rich region family protein 0.03 0.2147 0.3904
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.001 0.0001
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0046 0.0068
Echinococcus granulosus tyrosine protein kinase Lyn 0.0056 0.0323 0.0315
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0291 0.0567
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0174 0.0332
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0027 0.0034
Entamoeba histolytica hypothetical protein 0.0035 0.0167 0.0317
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0045 0.0066
Onchocerca volvulus 0.0019 0.0049 0.0076
Loa Loa (eye worm) raf kinase 0.0651 0.4764 0.8682
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0043 0.0064
Schistosoma mansoni cpg binding protein 0.0059 0.0347 0.0339
Brugia malayi C1-like domain containing protein 0.0027 0.0106 0.0177
Schistosoma mansoni netrin receptor unc5 0.0018 0.0042 0.0033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Schistosoma mansoni chromobox protein 0.0022 0.0071 0.0062
Brugia malayi Protein kinase domain containing protein 0.0018 0.004 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Leishmania major cytochrome p450-like protein 0.0019 0.0046 0.0075
Brugia malayi Prion-like- 0.0033 0.0149 0.0256
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0018 0.0083
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0232 0.0223
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus granulosus twitchin 0.0044 0.0232 0.0224
Onchocerca volvulus 0.0019 0.0049 0.0076
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0045 0.0036
Brugia malayi Presenilin-like protein At2g29900 0.007 0.0424 0.0759
Plasmodium vivax hypothetical protein, conserved 0.002 0.0056 0.1265
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0302 0.059
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0117 0.0235
Entamoeba histolytica hypothetical protein 0.0022 0.0071 0.0125
Schistosoma mansoni hypothetical protein 0.0018 0.0042 0.0033
Echinococcus multilocularis Immunoglobulin subtype 0.0018 0.0042 0.0033
Echinococcus multilocularis Diacylglycerol kinase theta 0.0023 0.0076 0.0067
Brugia malayi Protein kinase domain containing protein 0.002 0.0054 0.0083
Schistosoma mansoni hypothetical protein 0.0798 0.5862 0.5859
Loa Loa (eye worm) SRC-1 0.0052 0.0293 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Echinococcus granulosus chromobox protein 1 0.0079 0.0494 0.0486
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0056 0.0282
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Schistosoma mansoni netrin receptor unc5 0.0032 0.0146 0.0138
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0232 0.0408
Plasmodium vivax vivapain-2 0.0016 0.0027 0.049
Onchocerca volvulus 0.011 0.0724 0.1361
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0045 0.0036
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0064 0.0384 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0302 0.059
Echinococcus granulosus Diacylglycerol kinase theta 0.0023 0.0076 0.0067
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0294 0.0521
Echinococcus granulosus neuroglian 0.0033 0.0149 0.014
Schistosoma mansoni tyrosine kinase 0.0167 0.1152 0.1144
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Schistosoma mansoni cell adhesion molecule 0.0018 0.0042 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0128 0.0218
Brugia malayi hypothetical protein 0.0097 0.0627 0.113
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0167 0.0158
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0014 0.0012 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0027 0.0018
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0014 0.0009 0.0017
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0027 0.0035
Schistosoma mansoni titin 0.0014 0.0012 0.0004
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni cell adhesion molecule 0.0033 0.0149 0.014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0131 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Entamoeba histolytica hypothetical protein 0.0035 0.0167 0.0317
Brugia malayi SH2 domain containing protein 0.002 0.0054 0.0083
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.035 0.1636
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0027 0.0018
Echinococcus granulosus insulin growth factor binding 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0232 0.0465
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0365 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0106 0.0213
Onchocerca volvulus Peroxidasin homolog 0.0014 0.0012 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0165 0.0331
Echinococcus multilocularis titin 0.0018 0.0042 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0018 0.0265
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0045 0.0036
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0015 0.0006
Echinococcus multilocularis titin 0.0014 0.0012 0.0004
Schistosoma mansoni titin 0.0018 0.0042 0.0034
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0168 0.1157 0.5615
Entamoeba histolytica protein kinase, putative 0.0042 0.022 0.0425
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Immunoglobulin domain containing protein 0.0018 0.0042 0.0061
Loa Loa (eye worm) projectin 0.0014 0.0012 0.0007
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0071 0.0125
Echinococcus granulosus nephrin 0.0014 0.0012 0.0004
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0183 0.0175
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0024 0.0081 0.0072
Schistosoma mansoni rab6-interacting 0.0019 0.0049 0.004
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0019 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0167 0.0158
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0018 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0089
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0162
Echinococcus granulosus titin 0.0018 0.0042 0.0034
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0056 0.1265
Echinococcus multilocularis dihydrofolate reductase 0.0168 0.1157 0.115
Echinococcus granulosus titin 0.0014 0.0012 0.0004
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0173 0.0165
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0681 0.499 0.9094
Echinococcus multilocularis N chimaerin 0.0029 0.0121 0.0113
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0025 0.0095 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi CHD4 protein 0.0025 0.0095 0.0158
Echinococcus granulosus unc 13 munc13 0.0023 0.0076 0.0067
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0101 0.0169
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0174 0.0332
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.001 0.0003
Echinococcus multilocularis peroxidasin 0.0033 0.015 0.0142
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0018 0.002
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0033 0.0149 0.014
Onchocerca volvulus 0.0431 0.3124 0.5925
Echinococcus multilocularis RUN 0.0019 0.0049 0.004
Schistosoma mansoni titin 0.0014 0.0012 0.0004
Brugia malayi hypothetical protein 0.002 0.0056 0.0087
Schistosoma mansoni lipoxygenase 0.0019 0.0049 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0049 0.1065
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0115 0.0107
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0382 0.2753 0.501
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0232 0.0448
Entamoeba histolytica hypothetical protein 0.0023 0.0076 0.0134
Trypanosoma brucei Nicastrin, putative 0.0036 0.0171 0.0325
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0066
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0385 0.0756
Loa Loa (eye worm) hypothetical protein 0.011 0.0725 0.1308
Schistosoma mansoni cell adhesion molecule 0.0018 0.0042 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0178 0.0924
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.0056 0.0095
Echinococcus granulosus myotubularin protein 13 0.0023 0.0076 0.0067
Echinococcus multilocularis roundabout 2 0.0033 0.0149 0.014
Schistosoma mansoni basigin related 0.0018 0.0042 0.0033
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0018 0.0083
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0198 0.019
Brugia malayi hypothetical protein 0.002 0.0054 0.0083
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0018
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0176 0.1222 0.1214
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0114
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0018 0.0042 0.0033
Brugia malayi STAT protein, DNA binding domain containing protein 0.0132 0.0888 0.1606
Echinococcus multilocularis lamin dm0 0.0026 0.0101 0.0093
Leishmania major protein kinase, putative 0.0018 0.0039 0.0061
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0173 0.0347
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0332 0.0324
Onchocerca volvulus 0.0023 0.0076 0.0127
Toxoplasma gondii cathepsin CPL 0.0016 0.0027 0.0264
Brugia malayi diacylglycerol kinase 0.0023 0.0076 0.0122
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0014 0.001 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0083
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0688 0.5042 0.5038
Loa Loa (eye worm) TK protein kinase 0.0048 0.0266 0.047
Echinococcus multilocularis Immunoglobulin 0.0018 0.0042 0.0033
Schistosoma mansoni microtubule-associated protein tau 0.1352 1 1
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.0325
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0048 0.0266 0.0258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0293 0.0284
Brugia malayi Pre-SET motif family protein 0.0204 0.1427 0.2589
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0018
Trypanosoma cruzi Nicastrin, putative 0.0036 0.0171 0.0325
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0045 0.0036
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0329 0.0643
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Brugia malayi hypothetical protein 0.0019 0.0045 0.0066
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0071 0.1663
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0027 0.0037
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0033 0.0149 0.014
Giardia lamblia Kinase, PLK 0.0681 0.499 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0173 0.033
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0027 0.0018
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0027 0.0106 0.0097
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0045 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0291 0.1343
Trichomonas vaginalis STE family protein kinase 0.0014 0.0009 0.0017
Onchocerca volvulus 0.0014 0.0012 0.0007
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0018 0.0042 0.0033
Brugia malayi Pre-SET motif family protein 0.003 0.0131 0.0224
Schistosoma mansoni cpg binding protein 0.0056 0.0323 0.0315
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0232 0.0407
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0023 0.0076 0.0122
Schistosoma mansoni lamin 0.0026 0.0101 0.0093
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0101 0.0169
Schistosoma mansoni hypothetical protein 0.0019 0.0049 0.004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0049 0.004
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0018 0.0042 0.0033
Schistosoma mansoni protein kinase C 0.0023 0.0076 0.0067
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0018 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0198 0.1387 0.2767
Giardia lamblia Kinase, NEK 0.0014 0.0009 0.0002
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0018 0.0042 0.0062
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0027 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0369 0.0723
Onchocerca volvulus 0.0014 0.0012 0.0007
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0265 0.0256
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Schistosoma mansoni hypothetical protein 0.033 0.2366 0.2359
Echinococcus multilocularis gamma secretase subunit aph 1 0.0473 0.3438 0.3432
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.001 0.0003
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0175 0.1213 0.2199
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0287 0.2047 1
Entamoeba histolytica cysteine protease, putative 0.0016 0.0027 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Schistosoma mansoni nephrin related 0.0018 0.0042 0.0033
Echinococcus multilocularis insulin receptor 0.0104 0.0684 0.0676
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0039 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0081 0.0163
Entamoeba histolytica diacylglycerol kinase, putative 0.0023 0.0076 0.0134
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0101 0.0169
Loa Loa (eye worm) TK/ABL protein kinase 0.002 0.0054 0.0083
Brugia malayi SWIRM domain containing protein 0.002 0.0056 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0075 0.0066
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0018 0.002
Brugia malayi Presenilin spe-4 0.007 0.0424 0.0759
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0272 0.0501
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0049 0.1065
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0018 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0045 0.0036
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0012
Trichomonas vaginalis rotamase, putative 0.0032 0.0142 0.0285
Echinococcus multilocularis cpg binding protein 0.0059 0.0347 0.0339
Schistosoma mansoni protein kinase 0.0018 0.0039 0.003
Trypanosoma brucei polo-like protein kinase 0.0681 0.499 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0178 0.0924
Schistosoma mansoni serine/threonine protein kinase 0.0681 0.499 0.4986
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Leishmania major hypothetical protein, conserved 0.0056 0.0324 0.0633
Schistosoma mansoni septate junction protein 0.0033 0.0149 0.014
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0044 0.0232 0.0223
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus low density lipoprotein receptor ldl 0.0018 0.0042 0.0033
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.002 0.0056 0.0048
Echinococcus multilocularis musashi 0.0026 0.0101 0.0093
Loa Loa (eye worm) hypothetical protein 0.0026 0.0101 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Schistosoma mansoni slit 0.0015 0.0014 0.0005
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0045 0.0036
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0174 0.0332
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0033 0.0149 0.014
Echinococcus granulosus dnaJ subfamily B 0.0798 0.5862 0.5859
Echinococcus multilocularis integrin linked protein kinase 0.0014 0.0009 0.000000027283
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0052 0.0293 0.0284
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.0056 0.0095
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0027 0.049
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0018 0.0083
Echinococcus granulosus integrin linked protein kinase 0.0014 0.0009 0.000000027283
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0027 0.0018
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0173 0.0347
Trichomonas vaginalis rotamase, putative 0.0033 0.0148 0.0297
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0027 0.0034
Schistosoma mansoni hypothetical protein 0.033 0.2366 0.2359
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Schistosoma mansoni tyrosine kinase 0.0024 0.0081 0.0072
Echinococcus granulosus neuroglian 0.004 0.0202 0.0194
Echinococcus granulosus protein kinase c eta type 0.0023 0.0076 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0197
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.006 0.0103
Echinococcus granulosus tyrosine protein kinase otk 0.0033 0.0149 0.014
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0173 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0124 0.0249
Brugia malayi Inositol-1 0.0036 0.0173 0.0301
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0558 0.055
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0146 0.0138
Onchocerca volvulus 0.002 0.0054 0.0087
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0071 0.0125
Echinococcus granulosus presenilin enhancer 2 0.0186 0.1296 0.1288
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Leishmania major cathepsin L-like protease 0.0062 0.0369 0.0723
Onchocerca volvulus 0.0052 0.0297 0.0549
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0027 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.035 0.1835
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0198 0.1387 0.2779
Leishmania major cathepsin L-like protease 0.0016 0.0027 0.0037
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0173 0.0301
Plasmodium vivax hypothetical protein, conserved 0.002 0.0056 0.1265
Onchocerca volvulus 0.0014 0.0012 0.0007
Loa Loa (eye worm) oxidoreductase 0.0015 0.0018 0.0018
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0115 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1427 0.2589
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0043 0.0034
Echinococcus granulosus protein kinase c epsilon type 0.0027 0.0106 0.0097
Brugia malayi hypothetical protein 0.0019 0.0049 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0033 0.0149 0.014
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0302 0.059
Schistosoma mansoni cell adhesion molecule 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.003
Echinococcus granulosus defective proboscis extension response 0.0025 0.0095 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0087
Onchocerca volvulus 0.0014 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0061
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0385 0.0687
Brugia malayi Cathepsin L-like precursor 0.0016 0.0027 0.0034
Schistosoma mansoni cell adhesion molecule 0.0044 0.0232 0.0223
Echinococcus granulosus roundabout 2 0.0058 0.0339 0.033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0369 0.0723
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Brugia malayi Tyrosine-protein kinase abl-1 0.0024 0.0081 0.0132
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0293 0.0284
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0193 0.0863
Schistosoma mansoni nephrin 0.004 0.0202 0.0194
Echinococcus multilocularis tyrosine protein kinase otk 0.0033 0.0149 0.014
Onchocerca volvulus 0.002 0.0054 0.0087
Loa Loa (eye worm) hypothetical protein 0.0026 0.0098 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0291 0.1343
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0115 0.023
Onchocerca volvulus 0.0048 0.0265 0.0487
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0018 0.0018
Onchocerca volvulus Serine\/threonine kinase homolog 0.0681 0.499 0.9474
Schistosoma mansoni hypothetical protein 0.0022 0.0071 0.0062
Brugia malayi CXXC zinc finger family protein 0.0056 0.0323 0.0575
Schistosoma mansoni protein kinase 0.0014 0.0009 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0122 0.0244
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Schistosoma mansoni chromobox protein 0.0079 0.0494 0.0486
Schistosoma mansoni tyrosine kinase 0.0153 0.1049 0.1041
Echinococcus multilocularis neuroglian 0.0033 0.0149 0.014
Onchocerca volvulus 0.0014 0.0012 0.0007
Brugia malayi Doublecortin family protein 0.0019 0.0049 0.0073
Schistosoma mansoni tyrosine kinase 0.03 0.2147 0.2141
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0027 0.0106 0.0177
Brugia malayi RhoGAP domain containing protein 0.0023 0.0076 0.0122
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0232 0.0448
Schistosoma mansoni protein kinase 0.0018 0.0039 0.003
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0033 0.0149 0.014
Brugia malayi Protein kinase domain containing protein 0.0014 0.0009 0.000000049764
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni neuroglian 0.0033 0.0149 0.014
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0302 0.2157 0.3923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0165 0.0331
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0104 0.0684 0.0676
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Leishmania major cathepsin L-like protease 0.0016 0.0027 0.0037
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.011 0.0726 0.0718
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Loa Loa (eye worm) hypothetical protein 0.0031 0.0138 0.0236
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0071 0.0142
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0385 0.0756
Echinococcus multilocularis tumor protein p63 0.0329 0.2361 0.2354
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0291 0.2393
Schistosoma mansoni rotamase 0.0033 0.0148 0.014
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0198 0.1387 0.2779
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0167 0.0158
Brugia malayi follicle stimulating hormone receptor 0.023 0.1623 0.2947
Echinococcus granulosus tyrosine protein kinase Src42A 0.0052 0.0293 0.0284
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0369 0.0723
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.0494 0.0887
Onchocerca volvulus 0.0294 0.2099 0.3976
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Brugia malayi Protein kinase domain containing protein 0.0175 0.1213 0.2199
Echinococcus multilocularis 0.0014 0.0012 0.0004
Brugia malayi hypothetical protein 0.0097 0.0627 0.113
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0014 0.0009 0.0017
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0173 0.0165
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0365 0.065
Brugia malayi Heparan sulfate 0.0018 0.0042 0.0061
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.044 0.0432
Schistosoma mansoni dihydrofolate reductase 0.0168 0.1157 0.115
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0293 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0035 0.0027
Echinococcus granulosus Immunoglobulin 0.0018 0.0042 0.0033
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0018 0.0018
Brugia malayi hypothetical protein 0.0018 0.0042 0.0061
Loa Loa (eye worm) TK/INSR protein kinase 0.0104 0.0684 0.1232
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Brugia malayi Presenilin spe-4 0.007 0.0424 0.0759
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0131 0.1761
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Trypanosoma cruzi Aph-1 protein, putative 0.0184 0.1282 0.2556
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0033 0.0149 0.014
Schistosoma mansoni titin 0.0033 0.0149 0.014
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0064 0.0384 0.0754
Onchocerca volvulus 0.0014 0.0012 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0365 0.0356
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0052 0.0293 0.0284
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0306 0.0298
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0089
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0665 0.4868 0.4863
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0018 0.0042 0.0033
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0018 0.0042 0.0033
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0071 0.0062
Schistosoma mansoni septate junction protein 0.0018 0.0042 0.0033
Echinococcus granulosus lamin 0.0026 0.0101 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Echinococcus granulosus Chromobox protein 3 0.0022 0.0071 0.0062
Trichomonas vaginalis protein tyrosine kinase, putative 0.0014 0.0009 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0178 0.0924
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0071 0.1663
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0166 0.0332
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.002
Onchocerca volvulus 0.0016 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0114
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.002 0.0056 0.033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0045 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0165 0.0331
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.035 0.0624
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0291 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Disorganized muscle protein 1 0.0014 0.0012 0.0007
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0015 0.0006
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0052 0.0291 0.1343
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Schistosoma mansoni amine oxidase 0.002 0.0056 0.0048
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0156 0.0312
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0018
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0198 0.1387 0.1379
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0046 0.0136
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0106 0.0213
Schistosoma mansoni inositol monophosphatase 0.0036 0.0173 0.0165
Echinococcus multilocularis lachesin 0.0033 0.0149 0.014
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0494 0.0991
Onchocerca volvulus 0.0014 0.0012 0.0007
Echinococcus granulosus tyrosine protein kinase Fps85D 0.002 0.0054 0.0046
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0173 0.0301
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0473 0.3438 0.626
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0048 0.0266 0.0258
Mycobacterium ulcerans hypothetical protein 0.0052 0.0291 0.1343
Brugia malayi Dihydrofolate reductase 0.0168 0.1157 0.2097
Echinococcus multilocularis myotubularin protein 13 0.0023 0.0076 0.0067
Brugia malayi Cathepsin L-like precursor 0.0016 0.0027 0.0034
Brugia malayi protein unc-22 0.0018 0.0042 0.0062
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0323 0.0575
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0332 0.0324
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0297 0.0289
Entamoeba histolytica hypothetical protein 0.0022 0.0071 0.0125
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0018 0.0042 0.0033
Brugia malayi hypothetical protein 0.007 0.0424 0.0759
Brugia malayi Heterochromatin protein 1 0.0079 0.0494 0.0887
Brugia malayi PXA domain containing protein 0.0019 0.0045 0.0066
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0071 0.0062
Echinococcus granulosus presenilin 0.0198 0.1387 0.1379
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0027 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0365 0.0356
Trichomonas vaginalis Heterochromatin protein, putative 0.0022 0.0071 0.0142
Onchocerca volvulus Peroxidasin homolog 0.0016 0.0024 0.003
Echinococcus multilocularis chromobox protein 1 0.0079 0.0494 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus multilocularis cysteine protease 0.0016 0.0027 0.0018
Echinococcus granulosus gamma secretase subunit aph 1 0.0473 0.3438 0.3432
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0071 0.1663
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0332 0.0324
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0198 0.1387 0.2767
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0149 0.0256
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0166 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0014 0.0012 0.0007
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0018 0.0143
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) disorganized muscle protein 1 0.0014 0.0012 0.0007
Echinococcus multilocularis insulin growth factor binding 0.0014 0.0012 0.0004
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0018 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0042 0.0034
Brugia malayi gamma-secretase subunit aph-1 0.0473 0.3438 0.626
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0302 0.059
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0302 0.0294
Trypanosoma brucei protein kinase, putative 0.0018 0.0039 0.0061
Loa Loa (eye worm) presenilin spe-4 0.007 0.0424 0.0759
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0291 0.0515
Echinococcus granulosus tar DNA binding protein 0.0062 0.0365 0.0356
Loa Loa (eye worm) CAMK protein kinase 0.0018 0.0042 0.0062
Schistosoma mansoni diacylglycerol kinase theta 0.0023 0.0076 0.0067
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0045 0.0036
Onchocerca volvulus 0.002 0.0054 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0087
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0145 0.1112
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0302 0.0606
Giardia lamblia GTOR 0.0044 0.0232 0.0448
Echinococcus multilocularis nicalin 0.0036 0.0171 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0166 0.0332
Onchocerca volvulus Putative titin 0.0014 0.0012 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Onchocerca volvulus 0.0018 0.0042 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0232 0.0465
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0174 0.0166
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0052 0.0291 0.1522
Trypanosoma cruzi polo-like protein kinase, putative 0.0681 0.499 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0071 0.0125
Schistosoma mansoni protein kinase 0.0018 0.0039 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Entamoeba histolytica hypothetical protein 0.0035 0.0167 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0075 0.0066
Entamoeba histolytica hypothetical protein 0.0022 0.0071 0.0125
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0075 0.0121
Brugia malayi Cytochrome P450 family protein 0.0019 0.0046 0.0068
Echinococcus multilocularis protein kinase c iota type 0.0027 0.0106 0.0097
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.0095 0.0158
Loa Loa (eye worm) hypothetical protein 0.0048 0.0265 0.0468
Schistosoma mansoni hypothetical protein 0.0018 0.0042 0.0033
Mycobacterium ulcerans oxidoreductase 0.002 0.0056 0.0185
Onchocerca volvulus 0.0052 0.0291 0.0537
Schistosoma mansoni septate junction protein 0.0033 0.0149 0.014
Brugia malayi diacylglycerol kinase 0.0023 0.0076 0.0122
Loa Loa (eye worm) hypothetical protein 0.0036 0.0174 0.0302
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0114
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0291 0.0567
Echinococcus granulosus Nicastrin 0.0097 0.0627 0.0619
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0027 0.0106 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Schistosoma mansoni titin 0.0014 0.0012 0.0004
Schistosoma mansoni kinase 0.1176 0.8683 0.8682
Echinococcus granulosus tyrosine protein kinase shark 0.002 0.0055 0.0047
Schistosoma mansoni hypothetical protein 0.0014 0.001 0.0001
Loa Loa (eye worm) ctsf protein 0.0016 0.0027 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0302 0.0294
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0045 0.0036
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0014 0.0009 0.0017
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0018 0.0042 0.0033
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0027 0.0037
Loa Loa (eye worm) LAD-2 short isoform 0.0018 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0033 0.015 0.0259
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0166 0.0332
Echinococcus granulosus leucine rich repeat containing protein 4 0.0014 0.0012 0.0004
Echinococcus granulosus roundabout 2 0.0033 0.0149 0.014
Brugia malayi Prion-like- 0.0014 0.0012 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Chlamydia trachomatis dihydrofolate reductase 0.0168 0.1157 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0057 0.0332 0.059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0332 0.0324
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.1349 0.2703
Trichomonas vaginalis Nicastrin precursor, putative 0.0097 0.0627 0.1257
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Schistosoma mansoni cell adhesion molecule 0.0014 0.0012 0.0004
Brugia malayi hypothetical protein 0.0294 0.2099 0.3817
Schistosoma mansoni tyrosine kinase 0.0024 0.0081 0.0072
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.001 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus Protein kinase C brain isozyme 0.0027 0.0106 0.0097
Plasmodium falciparum heterochromatin protein 1 0.0022 0.0071 0.1663
Brugia malayi Protein kinase domain containing protein 0.002 0.0054 0.0083
Schistosoma mansoni vav2 0.0029 0.0121 0.0113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0174 0.0349
Loa Loa (eye worm) cysteine protease 0.0016 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0037 0.0179 0.0311
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Echinococcus granulosus lachesin 0.0033 0.0149 0.014
Onchocerca volvulus 0.069 0.5057 0.96
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0291 0.0515
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Plasmodium vivax protoporphyrinogen oxidase, putative 0.002 0.0056 0.1265
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0071 0.0062
Trichomonas vaginalis protein kinase atn1, putative 0.0014 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0238 0.168 0.3051
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0106 0.0097
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0365 0.0356
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0291 0.1522
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Brugia malayi Protein cec-1. 0.0022 0.0071 0.0114
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0293 0.0284
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0131 0.0123
Echinococcus multilocularis roundabout 2 0.0033 0.0149 0.014
Schistosoma mansoni protein kinase C mu 0.0027 0.0106 0.0097
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0018 0.0083
Brugia malayi basement membrane proteoglycan precursor 0.0018 0.0042 0.0061
Echinococcus granulosus titin 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.01 0.0201
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0193 0.4925
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0045 0.0036
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0014 0.0012 0.0004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0014 0.001
Entamoeba histolytica serine/threonine protein kinase, putative 0.0681 0.499 1
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0015 0.0014 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0082 0.0163
Schistosoma mansoni lozenge 0.0054 0.0309 0.0301
Schistosoma mansoni tyrosine kinase 0.0153 0.1049 0.1041
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0072
Loa Loa (eye worm) runx1 0.0054 0.0309 0.0549
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.035 0.0342
Schistosoma mansoni cell adhesion molecule 0.0033 0.0149 0.014
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0174 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Plasmodium vivax heterochromatin protein 1, putative 0.0022 0.0071 0.1663
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0018 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.003
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0018 0.0143
Brugia malayi hypothetical protein 0.0431 0.3124 0.5688
Schistosoma mansoni tyrosine kinase 0.0052 0.0293 0.0284
Entamoeba histolytica SH2-protein kinase domain containing protein 0.002 0.0054 0.0092
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0045 0.0036
Onchocerca volvulus 0.0016 0.0027 0.0035
Onchocerca volvulus 0.003 0.0128 0.0227
Schistosoma mansoni tyrosine kinase 0.0046 0.0252 0.0244
Schistosoma mansoni polycystin 1-related 0.0019 0.0049 0.004
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Echinococcus multilocularis roundabout 2 0.0058 0.0339 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.01 0.0201
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0106 0.0097
Echinococcus multilocularis presenilin 0.0198 0.1387 0.1379
Schistosoma mansoni inositol monophosphatase 0.0036 0.0173 0.0165
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0104 0.0684 0.0676
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0033 0.0149 0.0266
Schistosoma mansoni tyrosine kinase 0.0104 0.0684 0.0676
Onchocerca volvulus 0.0014 0.0009 0.000000051842
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.002 0.0056 0.1265
Brugia malayi gamma-secretase subunit pen-2 0.0186 0.1296 0.235
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Onchocerca volvulus 0.002 0.0056 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0066
Brugia malayi Cathepsin L-like precursor 0.0016 0.0027 0.0034
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0043 0.0062
Echinococcus granulosus chromobox protein 2 0.0022 0.0071 0.0062
Brugia malayi Immunoglobulin domain containing protein 0.0018 0.0042 0.0061
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0045 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0198 0.019
Brugia malayi Cytochrome P450 family protein 0.0019 0.0046 0.0068
Loa Loa (eye worm) TK protein kinase 0.0042 0.022 0.0387
Brugia malayi serine/threonine-protein kinase plk-2 0.0681 0.499 0.9094
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0018 0.0042 0.0061
Echinococcus multilocularis Ankyrin 0.0014 0.0011 0.0002
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0089
Echinococcus granulosus epidermal growth factor receptor 0.03 0.2147 0.2141
Leishmania major cathepsin L-like protease 0.0016 0.0027 0.0037
Loa Loa (eye worm) dihydrofolate reductase 0.0168 0.1157 0.2097
Echinococcus multilocularis expressed protein 0.0363 0.2618 0.2611
Echinococcus multilocularis Immunoglobulin 0.0025 0.0095 0.0087
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0049 0.004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0015 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0332 0.0324
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0369 0.0723
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0302 0.4215
Brugia malayi protein-tyrosine kinase 0.0048 0.0266 0.047
Schistosoma mansoni titin 0.0014 0.0012 0.0004
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0049 0.0073
Onchocerca volvulus 0.0023 0.0075 0.0126
Brugia malayi Leucine Rich Repeat family protein 0.0015 0.0014 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.033
Toxoplasma gondii hypothetical protein 0.007 0.0424 0.5961
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0011 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Echinococcus granulosus titin 0.0014 0.0012 0.0004
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0267 0.1896 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0291 0.1343
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.035 0.0342
Brugia malayi Immunoglobulin domain containing protein 0.0018 0.0042 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi MAP kinase sur-1 0.0053 0.0302 0.0536
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0061
Loa Loa (eye worm) follicle stimulating hormone receptor 0.023 0.1623 0.2947
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0039 0.0061
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0158
Echinococcus granulosus tyrosine protein kinase Blk 0.0048 0.0266 0.0258
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0175 0.1213 0.1206
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0302 0.0606
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0163 0.0154
Schistosoma mansoni hypothetical protein 0.0097 0.0627 0.0619
Schistosoma mansoni protein kinase 0.0014 0.0009 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Onchocerca volvulus 0.002 0.0054 0.0087
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0131 0.0123
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0033 0.0149 0.014
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0385 0.0756
Brugia malayi Animal haem peroxidase family protein 0.0014 0.0012 0.0007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0027 0.0018
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0365 0.065
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0302 0.059
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0142 0.0268
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0173 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Loa Loa (eye worm) hypothetical protein 0.0052 0.0291 0.0515
Onchocerca volvulus 0.0016 0.0027 0.0035
Echinococcus granulosus N chimaerin 0.0029 0.0121 0.0113
Echinococcus granulosus raf serine:threonine protein kinase 0.0665 0.4868 0.4863
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0045 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0057 0.0332 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Plasmodium falciparum protoporphyrinogen oxidase 0.002 0.0056 0.1265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Onchocerca volvulus 0.0056 0.0323 0.0599
Schistosoma mansoni hypothetical protein 0.0035 0.0167 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0156 0.0312
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0024 0.0082 0.1047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0165 0.0331
Loa Loa (eye worm) fibroinase 0.0016 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0097 0.0627 0.113
Onchocerca volvulus 0.0026 0.0101 0.0176
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0365 0.0356
Brugia malayi Protein kinase domain containing protein 0.0027 0.0106 0.0177
Schistosoma mansoni tyrosine kinase 0.0104 0.0684 0.0676
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0071 0.0142
Echinococcus multilocularis neuroglian 0.004 0.0202 0.0194
Schistosoma mansoni basigin related 0.0018 0.0042 0.0033
Brugia malayi kettin 0.0014 0.0012 0.0007
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0184 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0089
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0385 0.0756
Brugia malayi Uncoordinated protein 44 0.0014 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0149 0.0256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0018 0.0039 0.003
Entamoeba histolytica hypothetical protein 0.0035 0.0167 0.0317
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0018 0.0042 0.0033
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0071 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0385 0.0687
Loa Loa (eye worm) RNA binding protein 0.0062 0.0365 0.065
Echinococcus multilocularis Rac GTPase activating protein 1 0.0023 0.0076 0.0067
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0049 0.0073
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0075 0.0121
Schistosoma mansoni hypothetical protein 0.0018 0.0042 0.0033
Brugia malayi Protein kinase domain containing protein 0.0104 0.0684 0.1232
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0056 0.0324 0.0633
Schistosoma mansoni nephrin related 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0027 0.0054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus multilocularis chromobox protein 1 0.0079 0.0494 0.0486
Schistosoma mansoni hemicentin 0.0014 0.0012 0.0004
Echinococcus granulosus chromobox protein 1 0.0079 0.0494 0.0486
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0018 0.001
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0165 0.0315
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0071 0.0114
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0015 0.0012
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0045 0.0066
Echinococcus granulosus tumor protein p63 0.0329 0.2361 0.2354
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0027 0.0106 0.0177
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0293 0.0284
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0302 0.0606
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0302 0.0536
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0186 0.1296 0.235
Echinococcus multilocularis dnaJ subfamily B 0.0798 0.5862 0.5859
Onchocerca volvulus 0.0026 0.0101 0.0176
Schistosoma mansoni Lysine-specific histone demethylase 1 0.002 0.0056 0.0048
Brugia malayi Protein kinase domain containing protein 0.002 0.0054 0.0083
Echinococcus granulosus expressed protein 0.0363 0.2618 0.2611
Schistosoma mansoni rac gtpase activating protein 0.0023 0.0076 0.0067
Echinococcus granulosus insulin receptor 0.0104 0.0684 0.0676
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0291 0.0567
Brugia malayi RNA binding protein 0.0062 0.0365 0.065
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0071 0.0896
Schistosoma mansoni chromobox protein 0.0079 0.0494 0.0486
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0166 0.0332
Brugia malayi basement membrane proteoglycan 0.0018 0.0042 0.0061
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0293 0.0588
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0071 0.0062
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0052 0.0293 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0272 0.0545
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0082 0.0163
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0036
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0232 0.0448
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0332 0.0324
Brugia malayi Myb-like DNA-binding domain containing protein 0.0014 0.0012 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0291 0.0567
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Mycobacterium ulcerans dehydrogenase 0.002 0.0056 0.0185
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0058 0.0339 0.0603
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0018 0.0083
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0036
Echinococcus multilocularis tyrosine protein kinase Blk 0.0048 0.0266 0.0258
Brugia malayi integrin-linked kinase 0.0014 0.0009 0.000000049764
Schistosoma mansoni unc-13 (munc13) 0.0023 0.0076 0.0067
Echinococcus multilocularis tyrosine protein kinase shark 0.002 0.0055 0.0047
Loa Loa (eye worm) hypothetical protein 0.003 0.0131 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0017 0.0009
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0165 0.0315
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0018 0.0042 0.0061
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0075 0.0121
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0018 0.0042 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0089
Schistosoma mansoni titin 0.0014 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Onchocerca volvulus Tyrosine kinase homolog 0.0718 0.5267 1
Loa Loa (eye worm) STAT protein 0.0132 0.0888 0.1606
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0071 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Brugia malayi protein kinase C3,putative 0.0027 0.0106 0.0177
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0014 0.0012 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0029 0.0121 0.0206
Plasmodium vivax SET domain protein, putative 0.003 0.0131 0.3271
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0004
Brugia malayi hypothetical protein 0.007 0.0424 0.0759
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0291 0.2393
Onchocerca volvulus 0.0232 0.1637 0.3096
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0049 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi hypothetical protein 0.0035 0.0167 0.0289
Echinococcus multilocularis protein kinase c epsilon type 0.0027 0.0106 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Raf kinase 0.0642 0.4697 0.856
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0385 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0174 0.0349
Echinococcus granulosus tyrosine kinase 0.0048 0.0266 0.0258
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.044 0.0432
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0018 0.001
Echinococcus granulosus cathepsin l1 0.0016 0.0027 0.0018
Schistosoma mansoni roundabout 0.0033 0.0149 0.014
Onchocerca volvulus 0.0023 0.0076 0.0127
Echinococcus multilocularis lysine specific histone demethylase 1A 0.002 0.0056 0.0048
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0173 0.0165
Onchocerca volvulus 0.002 0.0054 0.0087
Echinococcus multilocularis tyrosine kinase 0.002 0.0054 0.0046
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0027 0.0106 0.0177
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.027 0.0524
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0045 0.0066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0095 0.0158
Echinococcus granulosus Immunoglobulin 0.0025 0.0095 0.0087
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0018 0.0018
Brugia malayi SRC-1 0.0052 0.0293 0.0519
Echinococcus multilocularis chromobox protein 2 0.0022 0.0071 0.0062
Echinococcus multilocularis geminin 0.033 0.2366 0.2359
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0012
Schistosoma mansoni tyrosine kinase 0.0167 0.1152 0.1144
Echinococcus multilocularis 0.002 0.0056 0.0048
Entamoeba histolytica acyl-coA synthetase, putative 0.0052 0.0291 0.0567
Schistosoma mansoni lipoxygenase 0.0054 0.0306 0.0298
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0681 0.499 0.4986
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0046 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0066
Echinococcus multilocularis Nicastrin 0.0097 0.0627 0.0619
Mycobacterium ulcerans monoamine oxidase 0.002 0.0056 0.0185
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0049 0.004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0332 0.0324
Trypanosoma brucei Aph-1 protein, putative 0.0184 0.1282 0.2556
Brugia malayi SET domain containing protein 0.0024 0.0088 0.0145
Echinococcus granulosus titin 0.0018 0.0042 0.0034
Brugia malayi Protein kinase domain containing protein 0.002 0.0054 0.0083
Echinococcus multilocularis Protein lozenge 0.0054 0.0309 0.0301
Echinococcus multilocularis 0.0089 0.0571 0.0563
Brugia malayi TAR-binding protein 0.0062 0.0365 0.065
Leishmania major cathepsin L-like protease 0.0062 0.0369 0.0723
Schistosoma mansoni intermediate filament proteins 0.0026 0.0101 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Brugia malayi chromobox protein homolog 3 0.0049 0.0272 0.0481
Echinococcus multilocularis hemicentin 1 0.0033 0.0149 0.014
Echinococcus granulosus geminin 0.033 0.2366 0.2359
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0293 0.0284
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0027 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0106 0.0097
Echinococcus multilocularis Nicastrin 0.0097 0.0627 0.0619
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0163 0.0154
Echinococcus granulosus expressed protein 0.0033 0.0148 0.014
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0232 0.0223
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0045 0.0036
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0014 0.0012 0.0004
Echinococcus multilocularis titin 0.0014 0.0012 0.0004
Onchocerca volvulus 0.0014 0.0012 0.0007
Toxoplasma gondii histone lysine-specific demethylase 0.002 0.0056 0.0681
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0131 0.0123
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0041 0.0059
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0071 0.0896
Echinococcus multilocularis transfer RNA-Phe 0.0014 0.0012 0.0004
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0193 0.1248
Echinococcus granulosus cpg binding protein 0.0059 0.0347 0.0339
Echinococcus granulosus roundabout 2 0.0033 0.0149 0.014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0066
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0558 0.055
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0148 0.0297
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0302 0.059
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0049 0.004
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0558 0.055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0122 0.0244
Brugia malayi Protein kinase domain containing protein 0.002 0.0054 0.0083
Onchocerca volvulus 0.0023 0.0076 0.0127
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0232 0.0448
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.001 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0083
Echinococcus granulosus contactin 0.0033 0.0149 0.014
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0142 0.0268
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0052 0.0293 0.0284
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0056 0.0048
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.002
Schistosoma mansoni vesicular amine transporter 0.0028 0.0113 0.0104
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0052 0.0291 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni myosin-binding protein-related 0.0014 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0046 0.0068
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0117 0.0206
Brugia malayi Prion-like- 0.0014 0.0012 0.0007
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0173 0.2361
Onchocerca volvulus 0.002 0.0054 0.0087
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0158
Trichomonas vaginalis TK family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus tyrosine kinase 0.002 0.0054 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Leishmania major cathepsin L-like protease 0.0062 0.0369 0.0723
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0148 0.0297
Loa Loa (eye worm) one IG domain family member 0.0014 0.0012 0.0007
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0052 0.0293 0.0284
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0029 0.0121 0.0206
Leishmania major cathepsin L-like protease 0.0016 0.0027 0.0037
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0173 0.0347
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0174 0.0166
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0114
Brugia malayi Protein kinase c protein 2 0.0027 0.0106 0.0177
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0232 0.0448
Onchocerca volvulus 0.0015 0.0014 0.001
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.002 0.0056 0.1265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0197
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0681 0.499 1
Onchocerca volvulus 0.0016 0.0027 0.0035
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0017 0.0009
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0018 0.0042 0.0033
Brugia malayi PXA domain containing protein 0.0019 0.0045 0.0066
Echinococcus multilocularis down syndrome cell adhesion 0.0014 0.0012 0.0004
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0145 0.0752
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0014 0.0009 0.000000049764
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0174 0.0332
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0071 0.1663
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0027 0.0106 0.0097
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0071 0.0142
Brugia malayi Prion-like- 0.0014 0.0012 0.0007
Brugia malayi hypothetical protein 0.011 0.0725 0.1308
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0029 0.0121 0.0113
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0045 0.0036
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0023 0.0076 0.0122
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0025 0.0095 0.0087
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Echinococcus multilocularis titin 0.0014 0.0012 0.0004
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0027 0.049
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0017 0.0009
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0071 0.0114
Loa Loa (eye worm) inositol-1 0.0036 0.0173 0.0301
Echinococcus multilocularis tyrosine protein kinase ABL1 0.002 0.0054 0.0046
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0045 0.0066
Echinococcus granulosus lamin dm0 0.0026 0.0101 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0014 0.0012 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0294 0.2099 0.3817
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0148 0.0255
Trypanosoma cruzi Nicastrin, putative 0.0036 0.0171 0.0325
Entamoeba histolytica hypothetical protein 0.0015 0.0019 0.0021
Schistosoma mansoni cpg binding protein 0.0059 0.0347 0.0339
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0082 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0232 0.0465
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.0095 0.0086
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0045 0.0066
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0018 0.0042 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0149 0.0256
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0012 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0365 0.0356
Loa Loa (eye worm) hypothetical protein 0.0052 0.0291 0.0515
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Onchocerca volvulus 0.0016 0.0027 0.0035
Loa Loa (eye worm) helicase 0.0022 0.0071 0.0114
Schistosoma mansoni tyrosine kinase 0.002 0.0054 0.0046
Trypanosoma brucei protein kinase, putative 0.0053 0.0302 0.059
Loa Loa (eye worm) hypothetical protein 0.0058 0.0339 0.0603
Brugia malayi Cathepsin L-like precursor 0.0016 0.0027 0.0034
Plasmodium falciparum protein kinase, putative 0.0018 0.0039 0.0804
Schistosoma mansoni nephrin 0.0033 0.0149 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0042 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0106 0.0097
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0148 0.2002
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0018 0.0042 0.0033
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0165 0.0315
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0027 0.0037
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.003
Echinococcus granulosus intermediate filament protein 0.0026 0.0101 0.0093
Brugia malayi hypothetical protein 0.0019 0.0045 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0027 0.0054
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0193 0.4925
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0064 0.0384 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.01 0.0201
Loa Loa (eye worm) hypothetical protein 0.0064 0.0381 0.068
Schistosoma mansoni diacylglycerol kinase theta 0.0023 0.0076 0.0067
Loa Loa (eye worm) hypothetical protein 0.0039 0.0193 0.0338
Onchocerca volvulus 0.0015 0.0018 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0166 0.0332
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0064 0.0384 0.5385
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.035 0.0342
Entamoeba histolytica ankyrin repeat protein 0.0014 0.0009 0.000000054723
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0302 0.0294
Brugia malayi M-phase phosphoprotein, mpp8 0.011 0.0724 0.1306
Echinococcus multilocularis tyrosine protein kinase Srms 0.0048 0.0266 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.1349 0.2703
Echinococcus granulosus peroxidasin 0.0033 0.015 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0054 0.0083
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0018 0.0265
Echinococcus multilocularis unc 13 (munc13) 0.0023 0.0076 0.0067
Toxoplasma gondii histone lysine methyltransferase SET1 0.0107 0.0706 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0291 0.0567
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0174 0.0166
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0087
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0081 0.0163
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0306 0.0298
Brugia malayi hypothetical protein 0.0025 0.0095 0.0158
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0039 0.0061
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0041 0.0065
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0029 0.0121 0.0113
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0173 0.033
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0681 0.499 1
Schistosoma mansoni chromobox protein 0.0022 0.0071 0.0062
Brugia malayi amine oxidase, flavin-containing family protein 0.002 0.0056 0.0087
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0017 0.0009
Echinococcus granulosus down syndrome cell adhesion 0.0014 0.0012 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0174 0.0166
Loa Loa (eye worm) hypothetical protein 0.0039 0.0193 0.0338
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0046 0.0075
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus multilocularis lamin 0.0026 0.0101 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0042 0.0061
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0291 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0302 0.0294
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0043 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0146 0.0251
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0052 0.0293 0.0284
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0007
Schistosoma mansoni atypical protein kinase C 0.0027 0.0106 0.0097
Trichomonas vaginalis Nicastrin precursor, putative 0.0097 0.0627 0.1257
Echinococcus multilocularis microtubule associated protein 2 0.1352 1 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0193 0.1007
Echinococcus granulosus Ankyrin 0.0014 0.0011 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0045 0.0036
Trypanosoma cruzi Aph-1 protein, putative 0.0184 0.1282 0.2556
Entamoeba histolytica protein kinase, putative 0.0014 0.0009 0.000000054723
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0302 0.059
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0071 0.0142
Brugia malayi Cytochrome P450 family protein 0.0029 0.0121 0.0205
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0033 0.0149 0.014
Echinococcus multilocularis epidermal growth factor receptor 0.03 0.2147 0.2141
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0385 0.0756
Echinococcus granulosus Immunoglobulin 0.0018 0.0042 0.0033
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0071 0.0896
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Brugia malayi dihydrofolate reductase family protein 0.0168 0.1157 0.2097
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0256
Schistosoma mansoni tyrosine kinase 0.0153 0.1049 0.1041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0076 0.0122
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0385 0.0377
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0142 0.0268
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0142 0.0268
Entamoeba histolytica diacylglycerol kinase, putative 0.0023 0.0076 0.0134
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.0076 0.0067
Toxoplasma gondii diacylglycerol kinase, putative 0.0023 0.0076 0.0961
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0232 0.0223
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0681 0.499 0.4986
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0018 0.0042 0.0033
Echinococcus granulosus activin receptor type 0.0018 0.0039 0.003
Echinococcus granulosus Immunoglobulin subtype 0.0018 0.0042 0.0033
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0174 0.0166
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0012
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0174 0.0166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0166 0.0332
Brugia malayi Ras association domain family 1 isoform A 0.0023 0.0076 0.0122
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0148 0.0255
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0158
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0174 0.0349
Echinococcus multilocularis twitchin 0.0018 0.0042 0.0034
Loa Loa (eye worm) hypothetical protein 0.0049 0.0272 0.0481
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.035 0.0686
Echinococcus granulosus hemicentin 1 0.0033 0.0149 0.014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Brugia malayi hypothetical protein 0.007 0.0424 0.0759
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.002
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0165 0.0331
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0302 0.059
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0017 0.0009
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0045 0.0036
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0198 0.1387 0.2779
Echinococcus granulosus RUN 0.0019 0.0049 0.004
Schistosoma mansoni unc-13 (munc13) 0.0023 0.0076 0.0067
Echinococcus multilocularis tyrosine protein kinase Abl 0.0024 0.0081 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0018 0.0083
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0071 0.0142
Schistosoma mansoni tyrosine kinase 0.002 0.0055 0.0047
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0748 0.5486 1
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0293 0.0588
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0064 0.0384 0.0754
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0004
Giardia lamblia Protein 21.1 0.0014 0.0009 0.000000054723
Echinococcus multilocularis protein kinase c eta type 0.0023 0.0076 0.0067
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0052 0.0293 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0012 0.0007
Echinococcus granulosus dihydrofolate reductase 0.0168 0.1157 0.115
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0002
Leishmania major UDP-galactopyranose mutase 0.002 0.0056 0.0095
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0045 0.0036
Brugia malayi SH2 domain containing protein 0.002 0.0054 0.0083
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0183 0.0175
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0045 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0272 0.0545
Schistosoma mansoni hypothetical protein 0.0018 0.0042 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0027 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus epidermal growth factor receptor 0.0167 0.1152 0.1144
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0071 0.0142
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0072
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Brugia malayi Fibronectin type III domain containing protein 0.0025 0.0095 0.0158
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0083
Onchocerca volvulus 0.0015 0.0018 0.0019
Schistosoma mansoni amine oxidase 0.002 0.0056 0.0048
Loa Loa (eye worm) TK/ROR protein kinase 0.0028 0.0115 0.0195
Mycobacterium ulcerans protoporphyrinogen oxidase 0.002 0.0056 0.0185
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0385 0.0377
Echinococcus multilocularis Immunoglobulin 0.0018 0.0042 0.0033
Echinococcus multilocularis cysteine protease 0.0016 0.0027 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0369 0.0723
Schistosoma mansoni hypothetical protein 0.0023 0.0076 0.0067
Schistosoma mansoni loxhd1 0.0019 0.0049 0.004
Brugia malayi intermediate filament protein 0.0026 0.0101 0.0169
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0174 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0014 0.0009 0.0017
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0018 0.0042 0.0033
Loa Loa (eye worm) hypothetical protein 0.0431 0.3124 0.5688
Echinococcus granulosus tyrosine protein kinase ABL1 0.002 0.0054 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0075 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0039 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0061

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 150 um PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1662 (Primary HTS)] ChEMBL. No reference
EC50 (functional) > 150 um PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1902 (Retest at Dose), 1900 (Counter Screen), 1662 (Primary HTS)] ChEMBL. No reference
Potency (functional) 1.2589 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.691 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 14.7157 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 20.5878 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 23.0999 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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