Detailed information for compound 68418

Basic information

Technical information
  • TDR Targets ID: 68418
  • Name: N-[[3-(2-chlorophenyl)-6-fluoro-4-oxoquinazol in-2-yl]methyl]-N-(2-fluorophenyl)acetamide
  • MW: 439.842 | Formula: C23H16ClF2N3O2
  • H donors: 0 H acceptors: 2 LogP: 4.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc2c(c1)c(=O)n(c(n2)CN(c1ccccc1F)C(=O)C)c1ccccc1Cl
  • InChi: 1S/C23H16ClF2N3O2/c1-14(30)28(21-9-5-3-7-18(21)26)13-22-27-19-11-10-15(25)12-16(19)23(31)29(22)20-8-4-2-6-17(20)24/h2-12H,13H2,1H3
  • InChiKey: XQXSDLXMWORERB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[[3-(2-chlorophenyl)-6-fluoro-4-oxo-quinazolin-2-yl]methyl]-N-(2-fluorophenyl)acetamide
  • N-[[3-(2-chlorophenyl)-6-fluoro-4-oxo-2-quinazolinyl]methyl]-N-(2-fluorophenyl)acetamide
  • N-[[3-(2-chlorophenyl)-6-fluoro-4-oxo-quinazolin-2-yl]methyl]-N-(2-fluorophenyl)ethanamide
  • N-[[3-(2-chlorophenyl)-6-fluoro-4-keto-quinazolin-2-yl]methyl]-N-(2-fluorophenyl)acetamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Glutamate receptor ionotropic, AMPA Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 Glutamate receptor ionotropic, AMPA   907 aa 948 aa 30.6 %
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 Glutamate receptor ionotropic, AMPA   907 aa 888 aa 34.0 %
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 Glutamate receptor ionotropic, AMPA   907 aa 886 aa 34.2 %
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 Glutamate receptor ionotropic, AMPA   907 aa 959 aa 30.9 %
Echinococcus multilocularis glutamate receptor 2 Glutamate receptor ionotropic, AMPA   907 aa 868 aa 30.4 %
Onchocerca volvulus Putative 39S ribosomal protein L45, mitochondrial Glutamate receptor ionotropic, AMPA   907 aa 799 aa 37.7 %
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 Glutamate receptor ionotropic, AMPA   907 aa 809 aa 34.1 %
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 Glutamate receptor ionotropic, AMPA   907 aa 779 aa 33.4 %
Echinococcus granulosus glutamate receptor 2 Glutamate receptor ionotropic, AMPA   907 aa 875 aa 30.4 %
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 Glutamate receptor ionotropic, AMPA   907 aa 779 aa 33.4 %
Drosophila melanogaster Glutamate receptor IIB Glutamate receptor ionotropic, AMPA   907 aa 863 aa 27.8 %
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 Glutamate receptor ionotropic, AMPA   907 aa 809 aa 33.6 %
Onchocerca volvulus Glutamate receptor ionotropic, AMPA   907 aa 796 aa 40.5 %
Drosophila melanogaster NMDA receptor 2 Glutamate receptor ionotropic, AMPA   907 aa 789 aa 22.1 %
Drosophila melanogaster Glutamate receptor IA Glutamate receptor ionotropic, AMPA   907 aa 900 aa 40.6 %
Schistosoma mansoni glutamate receptor kainate Glutamate receptor ionotropic, AMPA   907 aa 753 aa 33.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0073 0.0121
Loa Loa (eye worm) carbonic anhydrase 3 0.1145 0.5604 0.5604
Treponema pallidum fructose-bisphosphate aldolase 0.0307 0.1444 1
Schistosoma mansoni axis inhibition protein axin 0.0164 0.0733 0.1211
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0054 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Plasmodium falciparum carbonic anhydrase 0.0732 0.3553 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0263 0.0434
Echinococcus granulosus lysine specific histone demethylase 1A 0.0022 0.0025 0.0042
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0049 0.0088
Schistosoma mansoni hypothetical protein 0.0304 0.1426 0.2355
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.0733
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.0544 0.4064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Trichomonas vaginalis alpha chimerin, putative 0.0026 0.0049 0.0164
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0486 0.3624
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0022 0.0104
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0242 0.0399
Onchocerca volvulus 0.006 0.0214 0.0786
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0071 0.04
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0263 0.0463
Loa Loa (eye worm) RGS-3 protein 0.0164 0.0733 0.0733
Giardia lamblia Histone deacetylase 0.0296 0.1389 0.962
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0201 0.0359
Trypanosoma brucei histone deacetylase 2 0.0153 0.0677 0.1202
Echinococcus granulosus carbonic anhydrase 0.0732 0.3553 0.5866
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0146 0.0241
Brugia malayi DnaJ domain containing protein 0.0064 0.0238 0.0425
Plasmodium vivax PH domain containing protein 0.0026 0.0049 0.0258
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.024 0.0846
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0031 0.0071 0.0121
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0732 0.3553 0.6339
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0059 0.0105
Toxoplasma gondii AtPH1 family protein 0.0026 0.0049 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Brugia malayi RNA, U transporter 1 0.0081 0.032 0.0571
Entamoeba histolytica hypothetical protein 0.0164 0.0733 0.503
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0071 0.04
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0296 0.1389 0.4966
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0022 0.0025 0.0122
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0059 0.0059
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0026 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.0039 0.0112 0.0112
Brugia malayi Protein kinase domain containing protein 0.0031 0.0071 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0071 0.0243
Mycobacterium tuberculosis Conserved protein 0.0036 0.0094 0.0683
Loa Loa (eye worm) glutaminase 0.0579 0.2794 0.2794
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.0733
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0038 0.0106 0.0641
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0225 0.0372
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0054 0.0091
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0242 0.0242
Echinococcus multilocularis Rho GTPase activating protein 24 0.0026 0.0049 0.0082
Echinococcus granulosus oxysterol binding protein 9 0.0026 0.0049 0.0082
Echinococcus granulosus histone deacetylase 0.0375 0.178 0.2939
Schistosoma mansoni hypothetical protein 0.0732 0.3553 0.5866
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0071 0.04
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0073 0.0121
Echinococcus multilocularis dnaJ subfamily B 0.043 0.2054 0.3391
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0073 0.0131
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0006
Mycobacterium tuberculosis Possible oxidoreductase 0.0022 0.0025 0.0163
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0071 0.04
Plasmodium vivax SET domain protein, putative 0.0065 0.0239 0.1328
Onchocerca volvulus 0.0084 0.0338 0.1301
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Mycobacterium tuberculosis Conserved protein 0.0036 0.0094 0.0683
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0164 0.0733 0.0733
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0717
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0026 0.0049 0.0082
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0204 0.0336
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0054 0.0182
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.1727
Onchocerca volvulus 0.0087 0.0352 0.1362
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.037 0.1757 0.3135
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0284 0.1889
Schistosoma mansoni histone deacetylase hda2 0.0381 0.1812 0.2992
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0284 0.0791
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Brugia malayi Probable ClpP-like protease 0.0089 0.0362 0.0646
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0368 0.1748 0.2886
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0486 0.7212
Echinococcus granulosus snurportin 1 0.0304 0.1426 0.2355
Echinococcus multilocularis carbonic anhydrase 0.0732 0.3553 0.5866
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0204 0.0204
Schistosoma mansoni centaurin alpha 0.0026 0.0049 0.0082
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.0749 0.5602
Toxoplasma gondii histone lysine-specific demethylase 0.0022 0.0025 0.0061
Echinococcus multilocularis lamin dm0 0.0028 0.0059 0.0097
Schistosoma mansoni cpg binding protein 0.0059 0.0209 0.0345
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0049 0.0258
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0025 0.0043 0.0111
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0071 0.0191
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.04
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0317 0.1495 0.2663
Schistosoma mansoni oxysterol-binding protein 1 0.0026 0.0049 0.0082
Leishmania major GTP-binding protein, putative 0.0021 0.0022 0.0033
Trypanosoma brucei PH domain containing protein, putative 0.0026 0.0049 0.0082
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0002 0.0003
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0026 0.0049 0.0164
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Entamoeba histolytica PH domain containing protein 0.0026 0.0049 0.0246
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0089 0.0362 0.2018
Echinococcus granulosus Pleckstrin y 0.0026 0.0049 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1183 0.4228
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1145 0.5604 0.9253
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0073 0.0121
Trypanosoma cruzi histone deacetylase, putative 0.0375 0.178 0.3171
Schistosoma mansoni hypothetical protein 0.0084 0.0338 0.0557
Echinococcus multilocularis Polycystic kidney disease protein 0.0104 0.0433 0.0716
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0031 0.0071 0.0121
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0352 0.0581
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0571 0.0944
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 0.1285
Mycobacterium ulcerans beta-lactamase 0.0036 0.0094 0.0326
Entamoeba histolytica ARF GTPase activating protein, putative 0.0026 0.0049 0.0246
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0073 0.0073
Trichomonas vaginalis chaperonin, putative 0.0028 0.0056 0.0186
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0116 0.0192
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0089 0.0362 0.5276
Loa Loa (eye worm) hypothetical protein 0.0036 0.0094 0.0094
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0031 0.0071 0.0121
Echinococcus multilocularis Ras associated and pleckstrin y 0.0026 0.0049 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0025 0.0122
Plasmodium vivax histone deacetylase 2, putative 0.0375 0.178 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0073 0.0073
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0008 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0073 0.0131
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0165 0.0272
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0284 0.0501
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0056 0.0092
Brugia malayi A-kinase anchor protein 10, precursor 0.0164 0.0733 0.1309
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0073 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0071 0.0243
Schistosoma mansoni ATP-binding cassette transporter 0.003 0.0069 0.0113
Loa Loa (eye worm) hypothetical protein 0.0036 0.0094 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1183 0.4228
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0026 0.0049 0.0082
Schistosoma mansoni glutamate receptor NMDA 0.003 0.0069 0.0113
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0031 0.0071 0.0243
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Toxoplasma gondii histone deacetylase HDAC1 0.0375 0.178 0.5004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0116 0.0207
Leishmania major histone deacetylase, putative 0.0375 0.178 0.3171
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0073 0.0121
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 1
Echinococcus granulosus oxysterol binding protein 1 0.0026 0.0049 0.0082
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0209 0.0209
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0022 0.0033
Trypanosoma cruzi histone deacetylase 1, putative 0.0296 0.1389 0.2474
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0008 0.0013
Schistosoma mansoni alpha glucosidase 0.0074 0.0284 0.0469
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0246
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0362 0.101
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0225 0.0372
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0002 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0284 0.1889
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0028 0.0056 0.0093
Echinococcus granulosus lysine specific histone demethylase 1A 0.0022 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0056
Schistosoma mansoni oxysterol-binding protein 1 0.0026 0.0049 0.0082
Schistosoma mansoni hypothetical protein 0.0039 0.0112 0.0184
Trypanosoma brucei histone deacetylase 3 0.0375 0.178 0.3171
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0549 0.2645 0.4367
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0014 0.0023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0547 0.0903
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0748 0.3013
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0026 0.0049 0.0049
Brugia malayi Oxysterol-binding protein 0.0026 0.0049 0.0088
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.024 0.0396
Echinococcus granulosus GRB2 associated binding protein 3 0.0026 0.0049 0.0082
Toxoplasma gondii hypothetical protein 0.0732 0.3553 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0073 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1183 0.4228
Leishmania major hypothetical protein, conserved 0.0026 0.0049 0.0082
Loa Loa (eye worm) RNA binding protein 0.0132 0.0571 0.0571
Brugia malayi MAX-1A 0.0026 0.0049 0.0088
Echinococcus granulosus beta 1 syntrophin 0.0026 0.0049 0.0082
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0054 0.0281
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0204 0.0336
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0098 0.0338
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0033 0.0104
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.0733
Echinococcus multilocularis histone deacetylase 0.0375 0.178 0.2939
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0164 0.0733 0.1211
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0026 0.0049 0.0082
Trypanosoma brucei protein kinase, putative 0.0031 0.0071 0.0121
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0026 0.0049 0.0164
Schistosoma mansoni regulator of G protein signaling 0.0164 0.0733 0.1211
Schistosoma mansoni loxhd1 0.0104 0.0433 0.0716
Brugia malayi Regulator of G protein signaling domain containing protein 0.0164 0.0733 0.1309
Plasmodium vivax histone deacetylase, putative 0.0153 0.0677 0.3789
Echinococcus granulosus Oxysterol binding protein 11 0.0026 0.0049 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Schistosoma mansoni syntrophin 0.0026 0.0049 0.0082
Brugia malayi Dynamin 0.0026 0.0049 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0073 0.0131
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0026 0.0049 0.0129
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0116 0.0403
Mycobacterium ulcerans glutaminase 0.0579 0.2794 1
Echinococcus granulosus Rho GTPase activating protein 24 0.0026 0.0049 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Echinococcus granulosus histone deacetylase 7 0.0375 0.178 0.2939
Echinococcus multilocularis cytohesin 1 0.0026 0.0049 0.0082
Loa Loa (eye worm) histone methyltransferase 0.002 0.002 0.002
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0486 0.0486
Brugia malayi Matrixin family protein 0.006 0.0214 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0026 0.0049 0.0129
Schistosoma mansoni hypothetical protein 0.0026 0.0049 0.0082
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0026 0.0049 0.0082
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0054 0.0122
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0026 0.0049 0.0082
Toxoplasma gondii t-complex protein beta subunit 0.0028 0.0056 0.0147
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0352 0.0581
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0026 0.0049 0.0082
Loa Loa (eye worm) Plekhf2 protein 0.0026 0.0049 0.0049
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0031 0.0071 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1183 0.4228
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0664 0.118
Echinococcus granulosus regulator of G protein signaling 3 0.0164 0.0733 0.1211
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.0733
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0204 0.0336
Echinococcus granulosus geminin 0.0737 0.3577 0.5906
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0054 0.0182
Schistosoma mansoni serine/threonine-protein kinase 0.0031 0.0071 0.0118
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0094 0.0683
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0285 0.1334 1
Trypanosoma cruzi PH domain containing protein, putative 0.0026 0.0049 0.0082
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0118 0.0194
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0307 0.1441 0.5151
Echinococcus multilocularis histone deacetylase 8 0.0153 0.0677 0.1117
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0033 0.0052
Schistosoma mansoni myotubularin-related protein 0.0026 0.0049 0.0082
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0026 0.0049 0.0246
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0146 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0534 0.2572 0.4247
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.002 0.0032
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0172 0.0284
Onchocerca volvulus 0.0026 0.0049 0.01
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0036 0.0097 0.016
Loa Loa (eye worm) TAR-binding protein 0.0132 0.0571 0.0571
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0002 0.0003
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0054 0.0091
Brugia malayi hypothetical protein 0.0164 0.0733 0.1309
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0284 0.1006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.1045 0.783
Trypanosoma cruzi histone deacetylase, putative 0.0375 0.178 0.3171
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0036 0.0036
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0071 0.047
Brugia malayi Syntrophin-1 0.0026 0.0049 0.0088
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.0296 0.1389 0.4966
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0094 0.1084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0146 0.0241
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.014 0.0243
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0146 0.0241
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0481 0.3591
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0026 0.0049 0.0088
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0059 0.0059
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.037 0.1757 0.1757
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.024 0.1774
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.024 0.0427
Schistosoma mansoni zinc finger protein 0.0026 0.0049 0.0082
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0204 0.1389
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0073 0.0121
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0026 0.0049 0.0082
Mycobacterium leprae Probable lipase LipE 0.0036 0.0094 0.1084
Brugia malayi Histone deacetylase family protein 0.0375 0.178 0.3176
Echinococcus granulosus dnaJ subfamily B 0.043 0.2054 0.3391
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Brugia malayi 6-phosphofructokinase 0.0114 0.0486 0.0867
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0094 0.0162
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0571 0.0944
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0022 0.0025 0.0042
Entamoeba histolytica hypothetical protein 0.0164 0.0733 0.503
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0094 0.0683
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0307 0.1441 0.5151
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0204 0.0357
Onchocerca volvulus 0.0026 0.0049 0.01
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0111 0.0111
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0073 0.0121
Echinococcus multilocularis pleckstrin y domain containing family A 0.0026 0.0049 0.0082
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0028 0.0056 0.0092
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0073 0.02
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0026 0.0049 0.01
Entamoeba histolytica histone deacetylase, putative 0.0296 0.1389 0.9617
Brugia malayi hypothetical protein 0.0022 0.0025 0.0045
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0204 0.0357
Loa Loa (eye worm) hypothetical protein 0.0508 0.244 0.244
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0029 0.0061 0.0205
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0013
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0006 0.0004
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0017 0.0027
Brugia malayi PXA domain containing protein 0.0164 0.0733 0.1309
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0014 0.0023
Schistosoma mansoni carbonic anhydrase 0.0732 0.3553 0.5866
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0008 0.0014
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.0664 1
Brugia malayi Cadps2 protein 0.0026 0.0049 0.0088
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1145 0.5604 1
Mycobacterium ulcerans hydrolase 0.0073 0.0278 0.0985
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.004 0.1019
Brugia malayi MAP kinase sur-1 0.0058 0.0204 0.0364
Trypanosoma brucei glucosidase, putative 0.0074 0.0284 0.0501
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Brugia malayi Histone deacetylase family protein 0.0375 0.178 0.3176
Leishmania major DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Echinococcus multilocularis histone deacetylase 1 0.0296 0.1389 0.2294
Trypanosoma brucei histone deacetylase, putative 0.0375 0.178 0.3171
Brugia malayi hypothetical protein 0.0508 0.244 0.4354
Onchocerca volvulus 0.0026 0.0049 0.01
Brugia malayi glutaminase DH11.1 0.0579 0.2794 0.4986
Brugia malayi hypothetical protein 0.0164 0.0733 0.1309
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Echinococcus multilocularis glutamate receptor 2 0.003 0.0069 0.0113
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0026 0.0049 0.0258
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0094 0.0683
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.024 0.0421
Trichomonas vaginalis esterase, putative 0.0036 0.0094 0.0326
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Echinococcus granulosus axis inhibition protein axin 0.0164 0.0733 0.1211
Entamoeba histolytica hypothetical protein 0.0038 0.0106 0.0641
Leishmania major histone deacetylase, putative 0.0296 0.1389 0.2474
Echinococcus granulosus DCC interacting protein 13 beta 0.0026 0.0049 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0793 0.2829
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0071 0.0243
Echinococcus granulosus beta-adrenergic receptor kinase 0.1236 0.6057 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0284 0.1006
Brugia malayi nuclear receptor NHR-88 0.0031 0.0073 0.0131
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0071 0.1891
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0073 0.0121
Onchocerca volvulus Putative zinc finger protein 0.0026 0.0049 0.01
Entamoeba histolytica hypothetical protein 0.0025 0.004 0.0181
Schistosoma mansoni growth factor receptor-bound protein 0.0026 0.0049 0.0082
Echinococcus granulosus tar DNA binding protein 0.0132 0.0571 0.0944
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0026 0.0049 0.0082
Echinococcus multilocularis G protein coupled receptor kinase 6 0.037 0.1757 0.2901
Loa Loa (eye worm) hypothetical protein 0.0089 0.0362 0.0362
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Toxoplasma gondii hypothetical protein 0.0026 0.0049 0.0129
Echinococcus granulosus histone deacetylase 6 0.0375 0.178 0.2939
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0486 0.0802
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.006 0.0214 0.0353
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0188 0.033
Echinococcus granulosus microtubule associated protein 2 0.0725 0.3521 0.5814
Loa Loa (eye worm) hypothetical protein 0.0229 0.1053 0.1053
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0073 0.0121
Schistosoma mansoni cpg binding protein 0.0062 0.0226 0.0372
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0073 0.0121
Echinococcus granulosus histone deacetylase 1 0.0296 0.1389 0.2294
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.1495 0.2663
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0094 0.0326
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0225 0.0372
Mycobacterium ulcerans lipase LipD 0.0036 0.0094 0.0326
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.006 0.0214 0.0214
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0031 0.0071 0.0121
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0116 0.0781
Schistosoma mansoni ap endonuclease 0.004 0.0116 0.0192
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Trichomonas vaginalis histone deacetylase, putative 0.0296 0.1389 0.4966
Onchocerca volvulus Matrix metalloproteinase homolog 0.0132 0.0574 0.2287
Loa Loa (eye worm) hypothetical protein 0.006 0.0214 0.0214
Schistosoma mansoni cpg binding protein 0.0062 0.0226 0.0372
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0073 0.02
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0094 0.0683
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.1727
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0116 0.3139
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0128 0.0212
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0073 0.0121
Loa Loa (eye worm) uncoordinated protein 104 0.0026 0.0049 0.0049
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.014 0.0243
Echinococcus granulosus lipoxygenase domain containing protein 0.0104 0.0433 0.0716
Echinococcus multilocularis histone deacetylase 6 0.0375 0.178 0.2939
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0073 0.0121
Schistosoma mansoni glutamate receptor kainate 0.003 0.0069 0.0113
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0284 0.1006
Loa Loa (eye worm) DnaJ domain-containing protein 0.0064 0.0238 0.0238
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0263 0.0263
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0481 0.3591
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0022 0.0036
Echinococcus granulosus G protein coupled receptor kinase 1 0.1071 0.5241 0.8654
Brugia malayi glutathione reductase 0.005 0.0165 0.0294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0146 0.0241
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0116 0.0403
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0026 0.0049 0.0088
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0172 0.077 0.077
Toxoplasma gondii exonuclease III APE 0.004 0.0116 0.0317
Brugia malayi beta-lactamase 0.0036 0.0094 0.0169
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0008 0.0008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0073 0.0121
Loa Loa (eye worm) T-complex protein 1 0.0028 0.0056 0.0056
Trichomonas vaginalis protein kinase inhibitor, putative 0.0064 0.0238 0.084
Brugia malayi PAS domain containing protein 0.0051 0.0172 0.0307
Schistosoma mansoni alpha-glucosidase 0.0286 0.1339 0.221
Echinococcus granulosus expressed protein 0.0164 0.0733 0.1211
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0073 0.0073
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0036 0.0097 0.016
Schistosoma mansoni glutamate receptor kainate 0.003 0.0069 0.0113
Plasmodium falciparum LCCL domain-containing protein 0.0104 0.0433 0.1211
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0204 0.0357
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0059 0.0209 0.1545
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0263 0.0434
Schistosoma mansoni vav2 0.0026 0.0049 0.0082
Leishmania major serine/threonine-protein kinase a, putative 0.0031 0.0071 0.0121
Echinococcus granulosus intermediate filament protein 0.0028 0.0059 0.0097
Loa Loa (eye worm) hypothetical protein 0.0057 0.0201 0.0201
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0112 0.0199
Entamoeba histolytica hypothetical protein 0.0023 0.0033 0.0129
Plasmodium falciparum T-complex protein 1 subunit beta 0.0028 0.0056 0.0147
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0071 0.0243
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Echinococcus granulosus histone deacetylase 3 0.0296 0.1389 0.2294
Schistosoma mansoni glutamate receptor AMPA 0.003 0.0069 0.0113
Schistosoma mansoni ran 0.0021 0.0022 0.0036
Echinococcus granulosus GPCR family 2 0.0018 0.0008 0.0013
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0073 0.0121
Loa Loa (eye worm) glutamate receptor 1 0.003 0.0069 0.0069
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.04
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.004 0.0206
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0031 0.0071 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0094 0.0156
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0014 0.0023
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0164 0.0733 0.1211
Echinococcus multilocularis axis inhibition protein axin 0.0164 0.0733 0.1211
Onchocerca volvulus Matrilysin homolog 0.0132 0.0574 0.2287
Loa Loa (eye worm) hypothetical protein 0.0036 0.0094 0.0094
Echinococcus granulosus lipoxygenase domain containing protein 0.0104 0.0433 0.0716
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0239 0.0395
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0026 0.0049 0.0164
Echinococcus granulosus calcium dependent secretion activator 1 0.0026 0.0049 0.0082
Trypanosoma cruzi PH domain containing protein, putative 0.0026 0.0049 0.0082
Schistosoma mansoni histone deacetylase 0.0296 0.1389 0.2294
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0022 0.0128
Trichomonas vaginalis histone deacetylase, putative 0.0296 0.1389 0.4966
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0073 0.0121
Schistosoma mansoni single-minded 0.0051 0.0172 0.0284
Brugia malayi hypothetical protein 0.0026 0.0049 0.0088
Brugia malayi Matrixin family protein 0.006 0.0214 0.0382
Echinococcus multilocularis lipoxygenase domain containing protein 0.0104 0.0433 0.0716
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0303 0.05
Plasmodium falciparum PH domain-containing protein, putative 0.0026 0.0049 0.0129
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0284 0.0469
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Echinococcus multilocularis Regulator of G protein signaling 20 0.0164 0.0733 0.1211
Trypanosoma cruzi NIMA-related kinase, putative 0.0031 0.0071 0.0121
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0022 0.0022
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.004 0.0275
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0239 0.0395
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0022 0.0025 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0073 0.0131
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0246
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.1426 0.1426
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0239 0.0395
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0263 0.1738
Schistosoma mansoni histone deacetylase 4 5 0.0375 0.178 0.2939
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0164 0.0733 0.2615
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Echinococcus multilocularis carbonic anhydrase 0.0732 0.3553 0.5866
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0128 0.0212
Loa Loa (eye worm) hypothetical protein 0.0333 0.1575 0.1575
Entamoeba histolytica p21-activated kinase 0.0031 0.0071 0.04
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Mycobacterium tuberculosis Probable reductase 0.0113 0.0481 0.3591
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Onchocerca volvulus 0.0026 0.0049 0.01
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0284 0.0507
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0054 0.0091
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0014 0.0019
Schistosoma mansoni rab6-interacting 0.0104 0.0433 0.0716
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0486 0.0486
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0022 0.0025 0.0078
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0094 0.0511
Brugia malayi Protein kinase domain containing protein 0.002 0.0015 0.0027
Chlamydia trachomatis glutamine binding protein 0.0029 0.0061 0.1596
Onchocerca volvulus 0.0036 0.0094 0.0288
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0073 0.02
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0059 0.0099
Brugia malayi intermediate filament protein 0.0028 0.0059 0.0105
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Schistosoma mansoni axis inhibition protein axin 0.0164 0.0733 0.1211
Schistosoma mansoni serine/threonine protein kinase 0.1236 0.6057 1
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.1727
Schistosoma mansoni ap endonuclease 0.004 0.0116 0.0192
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0014 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0073 0.0131
Echinococcus multilocularis snurportin 1 0.0304 0.1426 0.2355
Echinococcus multilocularis regulator of G protein signaling 7 0.0164 0.0733 0.1211
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0352 0.0581
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0733 0.2615
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0022 0.0033
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0034 0.0085 0.0085
Onchocerca volvulus 0.0059 0.0209 0.0765
Trypanosoma cruzi histone deacetylase 1, putative 0.0296 0.1389 0.2474
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0014 0.0023
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0026 0.0049 0.0082
Schistosoma mansoni glutamate receptor NMDA 0.0036 0.0097 0.016
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Echinococcus multilocularis musashi 0.0028 0.0059 0.0097
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0059 0.0098
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0164 0.0733 0.1211
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0732 0.3553 0.6339
Trichomonas vaginalis centaurin gamma, putative 0.0026 0.0049 0.0164
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0104
Schistosoma mansoni coup transcription factor 0.0031 0.0073 0.0121
Brugia malayi Thioredoxin reductase 0.005 0.0165 0.0294
Brugia malayi hypoxia-induced factor 1 0.0158 0.0704 0.1257
Brugia malayi hypothetical protein 0.0104 0.0433 0.0774
Leishmania major hypothetical protein, conserved 0.0026 0.0049 0.0082
Toxoplasma gondii histone deacetylase HDAC4 0.0153 0.0677 0.1896
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Schistosoma mansoni hypothetical protein 0.0109 0.0459 0.0757
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0571 0.0944
Schistosoma mansoni hypothetical protein 0.043 0.2054 0.3391
Schistosoma mansoni intermediate filament proteins 0.0028 0.0059 0.0097
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.004 0.0103
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0352 0.0628
Leishmania major DNA polymerase eta, putative 0.0045 0.0141 0.0246
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0049 0.0246
Trichomonas vaginalis set domain proteins, putative 0.0505 0.2425 0.8675
Echinococcus granulosus histone deacetylase 6 0.0381 0.1812 0.2992
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0036 0.0097 0.016
Echinococcus multilocularis carbonic anhydrase 0.0732 0.3553 0.5866
Echinococcus multilocularis histone deacetylase 6 0.0375 0.178 0.2939
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Echinococcus multilocularis expressed protein 0.0164 0.0733 0.1211
Leishmania major protein kinase, putative 0.0031 0.0071 0.0121
Chlamydia trachomatis protoporphyrinogen oxidase 0.0022 0.0025 0.0605
Schistosoma mansoni hypothetical protein 0.0026 0.0049 0.0082
Trypanosoma cruzi PH domain containing protein, putative 0.0026 0.0049 0.0082
Schistosoma mansoni z-protein (S1r protein) 0.0164 0.0733 0.1211
Plasmodium falciparum histone deacetylase, putative 0.0375 0.178 0.5004
Trichomonas vaginalis histone deacetylase, putative 0.0296 0.1389 0.4966
Brugia malayi jmjC domain containing protein 0.0062 0.0225 0.0402
Echinococcus granulosus carbonic anhydrase II 0.1145 0.5604 0.9253
Schistosoma mansoni carbonic anhydrase-related 0.0732 0.3553 0.5866
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0368 0.1748 0.3119
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Brugia malayi Dynamin 0.0026 0.0049 0.0088
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.0731 0.1206
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0031 0.0071 0.019
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0164 0.0733 0.1211
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0284 0.0469
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Plasmodium falciparum calcium-dependent protein kinase 7 0.0031 0.0071 0.0191
Giardia lamblia Fructose-bisphosphate aldolase 0.0307 0.1444 1
Loa Loa (eye worm) glutamate receptor 2 0.003 0.0069 0.0069
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.1727
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0022 0.0025 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0071 0.0243
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0094 0.0326
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0094 0.0156
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1145 0.5604 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0303 0.05
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0116 0.0192
Trichomonas vaginalis histone deacetylase, putative 0.0296 0.1389 0.4966
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0481 0.3591
Entamoeba histolytica hypothetical protein 0.0164 0.0733 0.503
Echinococcus multilocularis Oxysterol binding protein 11 0.0026 0.0049 0.0082
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0731 0.1206
Brugia malayi CXXC zinc finger family protein 0.0059 0.0209 0.0373
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0026 0.0049 0.0049
Onchocerca volvulus 0.0505 0.2425 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0246
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0031 0.0071 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0094 0.0162
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0732 0.3553 0.6339
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0146 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0284 0.0501
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0106 0.0367
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0146 0.0241
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0263 0.0469
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0111 0.0197
Brugia malayi Matrixin family protein 0.0144 0.0633 0.113
Schistosoma mansoni rab6-interacting 0.0104 0.0433 0.0716
Echinococcus multilocularis GPCR, family 2 0.0018 0.0008 0.0013
Leishmania major histone deacetylase, putative 0.0375 0.178 0.3171
Echinococcus multilocularis axis inhibition protein axin 0.0164 0.0733 0.1211
Giardia lamblia TCP-1 chaperonin subunit beta 0.0028 0.0056 0.0361
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0296 0.1389 0.4966
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0026 0.0049 0.0246
Leishmania major trypanothione reductase 0.005 0.0165 0.0288
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0028 0.0056 0.0186
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0239 0.0395
Loa Loa (eye worm) AGC/AKT protein kinase 0.0031 0.0071 0.0071
Echinococcus granulosus regulator of G protein signaling 7 0.0164 0.0733 0.1211
Toxoplasma gondii phosphatidylinositol transfer protein 0.0026 0.0049 0.0129
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.1183 0.2112
Echinococcus multilocularis RUN 0.0104 0.0433 0.0716
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0029 0.0061 0.0397
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0026 0.0049 0.0082
Echinococcus multilocularis protoporphyrinogen oxidase 0.0022 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0104 0.0433 0.0433
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0204 0.0357
Brugia malayi TAR-binding protein 0.0132 0.0571 0.102
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0225 0.0372
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0054 0.0182
Echinococcus granulosus lysosomal alpha glucosidase 0.0332 0.1569 0.259
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.0664 0.2365
Mycobacterium ulcerans dehydrogenase 0.0022 0.0025 0.0078
Loa Loa (eye worm) rho-GTPase-activating 0.0026 0.0049 0.0049
Plasmodium vivax glutathione reductase, putative 0.005 0.0165 0.0908
Schistosoma mansoni histone deacetylase 0.0296 0.1389 0.2294
Onchocerca volvulus 0.0026 0.0049 0.01
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0022 0.0025 0.0042
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0014 0.0038
Echinococcus granulosus carbonic anhydrase 0.0732 0.3553 0.5866
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0073 0.0131
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0204 0.0336
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0014 0.0023
Echinococcus granulosus regulator of G protein signaling 3 0.0164 0.0733 0.1211
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Trypanosoma cruzi UDP-galactopyranose mutase 0.0022 0.0025 0.0039
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0029 0.0061 0.0397
Echinococcus multilocularis dnaJ subfamily C 6 0.0064 0.0238 0.0393
Brugia malayi Glutamate receptor 1 precursor 0.003 0.0069 0.0122
Trichomonas vaginalis hypothetical protein 0.0026 0.0049 0.0164
Echinococcus multilocularis calcium dependent secretion activator 1 0.0026 0.0049 0.0082
Onchocerca volvulus 0.0026 0.0049 0.01
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.004 0.0131
Brugia malayi PXA domain containing protein 0.0164 0.0733 0.1309
Echinococcus multilocularis glutamate receptor 2 0.0036 0.0097 0.016
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0014 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0284 0.1006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0022 0.0033
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0071 0.1891
Onchocerca volvulus 0.0036 0.0094 0.0288
Leishmania major protein kinase, putative 0.0031 0.0071 0.0121
Onchocerca volvulus 0.0026 0.0049 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Plasmodium falciparum thioredoxin reductase 0.005 0.0165 0.0455
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.014 0.0243
Echinococcus multilocularis beta adrenergic receptor kinase 0.1236 0.6057 1
Echinococcus granulosus carbonic anhydrase 0.0732 0.3553 0.5866
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0094 0.0326
Toxoplasma gondii histone deacetylase HDAC5 0.0153 0.0677 0.1898
Brugia malayi follicle stimulating hormone receptor 0.0243 0.1127 0.2012
Echinococcus multilocularis lysosomal alpha glucosidase 0.0332 0.1569 0.259
Schistosoma mansoni hypothetical protein 0.0737 0.3577 0.5906
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0239 0.0665
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0243 0.1127 0.1127
Echinococcus granulosus survival motor neuron protein 1 0.0508 0.244 0.4029
Schistosoma mansoni histone deacetylase 4 5 0.0375 0.178 0.2939
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0094 0.0326
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0073 0.0073
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0486 0.0861
Toxoplasma gondii ABC1 family protein 0.0036 0.0094 0.0256
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.0544 0.8128
Echinococcus granulosus lamin 0.0028 0.0059 0.0097
Onchocerca volvulus 0.0038 0.0106 0.0337
Brugia malayi Importin beta-1 subunit 0.0028 0.0059 0.0106
Plasmodium vivax histone deacetylase, putative 0.0375 0.178 1
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Mycobacterium ulcerans oxidoreductase 0.0022 0.0025 0.0078
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0026 0.0049 0.0049
Mycobacterium leprae PROBABLE HYDROLASE 0.0073 0.0278 0.3965
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0026 0.0049 0.0246
Loa Loa (eye worm) histone deacetylase 3 0.0296 0.1389 0.1389
Brugia malayi hypothetical protein 0.0128 0.0554 0.0988
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0073 0.0121
Mycobacterium ulcerans hypothetical protein 0.0167 0.0749 0.267
Plasmodium vivax importin-beta 2, putative 0.0028 0.0059 0.0314
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.1444 1
Schistosoma mansoni carbonic anhydrase-related 0.0732 0.3553 0.5866
Schistosoma mansoni zinc finger protein 0.0026 0.0049 0.0082
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 0.2488
Echinococcus multilocularis lamin 0.0028 0.0059 0.0097
Schistosoma mansoni glutamate receptor AMPA 0.003 0.0069 0.0113
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0036 0.0097 0.016
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0028 0.0056 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Onchocerca volvulus 0.0031 0.0073 0.02
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.004 0.0254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0071 0.0243
Trichomonas vaginalis kinesin light chain, putative 0.0026 0.0049 0.0164
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0089 0.0362 0.0598
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.003 0.0069 0.0113
Trypanosoma brucei rac serine-threonine kinase, putative 0.0031 0.0071 0.0121
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0075 0.0127
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0731 0.1206
Leishmania major mitochondrial DNA polymerase beta 0.0317 0.1495 0.2663
Trichomonas vaginalis protein transport protein sec7, putative 0.0026 0.0049 0.0164
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0014 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0793 0.2829
Onchocerca volvulus 0.0104 0.0433 0.1701
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0481 0.7144
Echinococcus granulosus peptidase Clp S14 family 0.0059 0.0209 0.0345
Schistosoma mansoni hypothetical protein 0.0026 0.0049 0.0082
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.004 0.0131
Echinococcus granulosus RUN 0.0104 0.0433 0.0716
Schistosoma mansoni dynamin 0.0026 0.0049 0.0082
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0025 0.0122
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0026 0.0049 0.0082
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0073 0.0278 0.2066
Leishmania major DNA polymerase eta, putative 0.0032 0.0075 0.0127
Loa Loa (eye worm) syntrophin-1 0.0026 0.0049 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0014 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0571 0.0944
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0056 0.0092
Echinococcus multilocularis rac serine:threonine kinase 0.0031 0.0071 0.0118
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0534 0.2572 0.459
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0717
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0486 0.0861
Leishmania major importin beta-1 subunit, putative 0.0023 0.0033 0.0052
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0071 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0026 0.0049 0.0246
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0362 0.101
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Echinococcus multilocularis GRB2 associated binding protein 3 0.0026 0.0049 0.0082
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0094 0.0156
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.1236 0.6057 0.6057
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0031 0.0071 0.0382
Schistosoma mansoni survival motor neuron protein 0.0104 0.0432 0.0714
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0073 0.0121
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.004 0.0103
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0094 0.0683
Echinococcus granulosus pleckstrin y domain containing family A 0.0026 0.0049 0.0082
Brugia malayi Cytochrome P450 family protein 0.0024 0.0036 0.0064
Mycobacterium leprae conserved hypothetical protein 0.0025 0.004 0.0233
Loa Loa (eye worm) hypothetical protein 0.0036 0.0094 0.0094
Loa Loa (eye worm) matrixin family protein 0.0132 0.0574 0.0574
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0026 0.0049 0.0082
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0036 0.0097 0.016
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.0575 0.095
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Toxoplasma gondii thioredoxin reductase 0.005 0.0165 0.0455
Schistosoma mansoni histone deacetylase 1 2 3 0.0153 0.0677 0.1117
Onchocerca volvulus 0.0065 0.0239 0.0892
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.0056 0.0099
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0106 0.0175
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0026 0.0049 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0014 0.0025
Plasmodium falciparum importin beta, putative 0.0028 0.0059 0.0157
Echinococcus granulosus glutamate receptor 2 0.0025 0.0041 0.0068
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.0664 0.4962
Loa Loa (eye worm) oxysterol binding protein 0.0026 0.0049 0.0049
Echinococcus granulosus glutamate receptor 2 0.0036 0.0097 0.016
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0071 0.0382
Loa Loa (eye worm) hypothetical protein 0.0222 0.1021 0.1021
Echinococcus granulosus cpg binding protein 0.0062 0.0226 0.0372
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0284 0.1006
Brugia malayi Matrixin family protein 0.006 0.0214 0.0382
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0073 0.0278 0.0497
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0146 0.0241
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0031 0.0071 0.0191
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0481 0.3591
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0104
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0031 0.0071 0.0243
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0071 0.0382
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0332 0.1569 0.1569
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0054 0.0182
Trypanosoma cruzi PH domain containing protein, putative 0.0026 0.0049 0.0082
Echinococcus multilocularis beta 1 syntrophin 0.0026 0.0049 0.0082
Toxoplasma gondii hypothetical protein 0.0026 0.0049 0.0129
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0014 0.0038
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0732 0.3553 0.6339
Echinococcus multilocularis Pleckstrin y 0.0026 0.0049 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0022 0.0052
Schistosoma mansoni hypothetical protein 0.0026 0.0049 0.0082
Toxoplasma gondii Oxysterol-binding protein 0.0026 0.0049 0.0129
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0116 0.0846
Loa Loa (eye worm) glutaminase 2 0.0579 0.2794 0.2794
Schistosoma mansoni hypothetical protein 0.0104 0.0433 0.0716
Plasmodium vivax histone deacetylase 1, putative 0.0296 0.1389 0.7802
Echinococcus multilocularis regulator of G protein signaling 3 0.0164 0.0733 0.1211
Brugia malayi hypothetical protein 0.0104 0.0433 0.0774
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0022 0.0052
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0263 0.0463
Echinococcus granulosus oxysterol binding protein 3 0.0026 0.0049 0.0082
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0026 0.0049 0.0258
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0059
Toxoplasma gondii histone deacetylase HDAC3 0.0296 0.1389 0.3905
Echinococcus multilocularis actin binding protein anillin 0.0026 0.0049 0.0082
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0239 0.0395
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0026 0.0049 0.0082
Echinococcus granulosus nmda type glutamate receptor 0.004 0.0116 0.0192
Echinococcus multilocularis oxysterol binding protein 3 0.0026 0.0049 0.0082
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0094 0.0683
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0106 0.0175
Echinococcus multilocularis oxysterol binding protein 1 0.0026 0.0049 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Brugia malayi jmjC domain containing protein 0.0065 0.0242 0.0431
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0028 0.0056 0.0293
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0073 0.0131
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Schistosoma mansoni dynamin 0.0026 0.0049 0.0082
Onchocerca volvulus Histone deacetylase 10 homolog 0.0153 0.0677 0.2714
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.014 0.0243
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0014 0.008
Echinococcus multilocularis myotubularin protein 13 0.0026 0.0049 0.0082
Echinococcus granulosus histone deacetylase 8 0.0153 0.0677 0.1117
Echinococcus granulosus serine/threonine protein kinase 0.0031 0.0071 0.0118
Trichomonas vaginalis histone deacetylase, putative 0.0296 0.1389 0.4966
Schistosoma mansoni ran 0.0021 0.0022 0.0036
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.024 0.0396
Trichomonas vaginalis centaurin alpha, putative 0.0026 0.0049 0.0164
Brugia malayi histone deacetylase 3 (HD3) 0.0296 0.1389 0.2479
Brugia malayi hypothetical protein 0.0172 0.077 0.1374
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0026 0.0049 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0284 0.0284
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0201 0.0359
Plasmodium falciparum glutathione reductase 0.005 0.0165 0.0455
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0089 0.0362 0.0598
Leishmania major T-complex protein 1, beta subunit, putative 0.0028 0.0056 0.0093
Echinococcus granulosus lamin dm0 0.0028 0.0059 0.0097
Leishmania major protein kinase, putative 0.0018 0.0006 0.0004
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0026 0.0049 0.0129
Plasmodium vivax multidomain scavenger receptor, putative 0.0104 0.0433 0.242
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0733 0.2615
Trypanosoma brucei unspecified product 0.0019 0.0014 0.0019
Trypanosoma cruzi histone deacetylase, putative 0.0375 0.178 0.3171
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0284 0.1006
Loa Loa (eye worm) matrixin family protein 0.0144 0.0633 0.0633
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0141 0.0252
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.1495 0.2663
Leishmania major protein kinase, putative 0.0023 0.0032 0.005
Trypanosoma brucei histone deacetylase 4 0.0375 0.178 0.3171
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0006 0.0004
Mycobacterium tuberculosis Conserved protein 0.0036 0.0094 0.0683
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0054 0.0097
Brugia malayi Oxysterol binding protein 0.0026 0.0049 0.0088
Onchocerca volvulus Protein melted homolog 0.0026 0.0049 0.01
Schistosoma mansoni amine oxidase 0.0022 0.0025 0.0042
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0071 0.0191
Brugia malayi PH domain containing protein 0.0026 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.0732 0.3553 0.3553
Trypanosoma brucei trypanothione reductase 0.005 0.0165 0.0288
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.004 0.0065
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0073 0.0131
Schistosoma mansoni amine oxidase 0.0022 0.0025 0.0042
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0242 0.0399
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0026 0.0049 0.0082
Echinococcus granulosus transcription factor Dp 1 0.004 0.0118 0.0194
Schistosoma mansoni hypothetical protein 0.0104 0.0432 0.0714
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0008 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0018 0.0033
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0296 0.1389 0.1389
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0031 0.0071 0.0121
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0059 0.0209 0.1545
Echinococcus granulosus single minded 2 0.0041 0.0124 0.0204
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0094 0.0683
Schistosoma mansoni lipoxygenase 0.0549 0.2645 0.4367
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0029 0.0061 0.1596
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0071 0.0243
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0443 0.2121 0.2121
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.024 0.0846
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0732 0.3553 0.3553
Brugia malayi Glycosyl hydrolases family 31 protein 0.0332 0.1569 0.2799
Echinococcus granulosus cytohesin 1 0.0026 0.0049 0.0082
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0059 0.0209 0.288
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0029 0.0061 0.043
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0717
Brugia malayi steroid hormone receptor 0.0031 0.0073 0.0131
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0111 0.0183
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0534 0.2572 0.2572
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0008 0.0013
Toxoplasma gondii histone deacetylase HDAC2 0.0296 0.1389 0.3905
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0204 0.0564
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0073 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0717
Echinococcus multilocularis tar DNA binding protein 0.0132 0.0571 0.0944
Echinococcus multilocularis histone deacetylase 7 0.0375 0.178 0.2939
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0026 0.0049 0.0164
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0073 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0073 0.0073
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1145 0.5604 1
Onchocerca volvulus Matrilysin homolog 0.006 0.0214 0.0786
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0201 0.0201
Echinococcus multilocularis lipoxygenase domain containing protein 0.0104 0.0433 0.0716
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0733 0.2615
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0073 0.0131
Trypanosoma brucei histone deacetylase 1 0.0296 0.1389 0.2474
Echinococcus multilocularis carbonic anhydrase II 0.1145 0.5604 0.9253
Onchocerca volvulus 0.0028 0.0059 0.014
Echinococcus granulosus Regulator of G protein signaling 20 0.0164 0.0733 0.1211
Echinococcus multilocularis 0.0022 0.0025 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0073 0.0121
Echinococcus multilocularis histone deacetylase 6 0.0381 0.1812 0.2992
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0025 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0073 0.0131
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0165 0.1213
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0036 0.0097 0.016
Brugia malayi regulator of G-protein signaling rgs-7 0.0164 0.0733 0.1309
Loa Loa (eye worm) histone deacetylase 7A 0.0375 0.178 0.178
Plasmodium falciparum oxysterol-binding protein, putative 0.0026 0.0049 0.0129
Echinococcus multilocularis dna polymerase eta 0.0045 0.0141 0.0233
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0486 0.0802
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0549 0.2645 0.4367
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Schistosoma mansoni lamin 0.0028 0.0059 0.0097
Loa Loa (eye worm) hypothetical protein 0.0065 0.0239 0.0239
Echinococcus multilocularis Pleckstrin y 0.0026 0.0049 0.0082
Trichomonas vaginalis centaurin/arf, putative 0.0026 0.0049 0.0164
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Schistosoma mansoni glutaminase 0.0579 0.2794 0.4613
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0031 0.0071 0.038
Echinococcus granulosus histone deacetylase 6 0.0375 0.178 0.2939
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1145 0.5604 0.9253
Brugia malayi Regulator of G protein signaling domain containing protein 0.0164 0.0733 0.1309
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0026 0.0049 0.0082
Schistosoma mansoni regulator of G protein signaling 0.0164 0.0733 0.1211
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Schistosoma mansoni serine/threonine-protein kinase 0.0031 0.0071 0.0118
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0094 0.0326
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0026 0.0049 0.0246
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0031 0.0071 0.0121
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0239 0.0395
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 0.1285
Trypanosoma cruzi NIMA-related kinase, putative 0.0031 0.0071 0.0121
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0073 0.0121
Plasmodium falciparum histone deacetylase 2 0.0375 0.178 0.5004
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Echinococcus multilocularis glutamate receptor 2 0.0025 0.0041 0.0068
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0026 0.0049 0.0082
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0204 0.0357
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0073 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0073 0.0121
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0014 0.0038
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1145 0.5604 0.5604
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 0.101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Echinococcus multilocularis regulator of G protein signaling 7 0.0164 0.0733 0.1211
Loa Loa (eye worm) hypothetical protein 0.0073 0.0278 0.0278
Loa Loa (eye worm) matrix metalloproteinase 0.006 0.0214 0.0214
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.037 0.1757 0.1757
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0104 0.0432 0.0772
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0073 0.0121
Loa Loa (eye worm) PH domain-containing protein 0.0026 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0153 0.0677 0.0677
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0008 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0165 0.0288
Entamoeba histolytica hypothetical protein 0.0038 0.0106 0.0641
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0002 0.0003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0263 0.0463
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0026 0.0049 0.0049
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0732 0.3553 0.6339
Schistosoma mansoni microtubule-associated protein tau 0.0725 0.3521 0.5814
Loa Loa (eye worm) histone deacetylase 0.0375 0.178 0.178
Echinococcus granulosus dna polymerase eta 0.0045 0.0141 0.0233
Entamoeba histolytica PH domain containing protein 0.0026 0.0049 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0026 0.0049 0.0082
Brugia malayi Uncoordinated protein 104 0.0026 0.0049 0.0088
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0098 0.0338
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Brugia malayi histone deacetylase 11 0.0153 0.0677 0.1207
Echinococcus multilocularis peptidase Clp (S14 family) 0.0059 0.0209 0.0345
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0022 0.0039
Leishmania major UDP-galactopyranose mutase 0.0022 0.0025 0.0039
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0031 0.0071 0.0121
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0368 0.1748 0.2886
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.002 0.0032
Schistosoma mansoni hypothetical protein 0.0132 0.0575 0.095
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0059 0.0099
Brugia malayi Pre-SET motif family protein 0.0065 0.0239 0.0427
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0073 0.0121
Brugia malayi Doublecortin family protein 0.0104 0.0433 0.0774
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0116 0.0201
Echinococcus granulosus Polycystic kidney disease protein 0.0104 0.0433 0.0716
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0116 0.0781
Echinococcus multilocularis oxysterol binding protein 9 0.0026 0.0049 0.0082
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0031 0.0071 0.0468
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0733 0.2615
Trypanosoma brucei RNA helicase, putative 0.0109 0.0459 0.0812
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.0664 0.118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0087 0.0352 0.0352
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0116 0.0201
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0094 0.0162
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0239 0.0395
Echinococcus granulosus Pleckstrin y 0.0026 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Brugia malayi Pleckstrin Homology Domain 0.0026 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.006 0.0214 0.0214
Trichomonas vaginalis centaurin beta, putative 0.0026 0.0049 0.0164
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.0575 0.095
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0022 0.0025 0.0122
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0026 0.0049 0.0164
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0026 0.0049 0.0082
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0094 0.0326
Echinococcus multilocularis nmda type glutamate receptor 0.004 0.0116 0.0192
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.0544 0.4064
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0054 0.0182
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0296 0.1389 0.4966
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.004 0.1019
Onchocerca volvulus 0.0192 0.0873 0.3531
Entamoeba histolytica protein kinase, putative 0.0031 0.0071 0.04
Brugia malayi SWIRM domain containing protein 0.0022 0.0025 0.0045
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0486 0.0802
Giardia lamblia DINP protein human, muc B family 0.0019 0.0014 0.0074
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0116 0.0201
Echinococcus multilocularis regulator of G protein signaling 0.0164 0.0733 0.1211
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0075 0.0201
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0026 0.0049 0.0082
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0071 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0073 0.0131
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Loa Loa (eye worm) glutathione reductase 0.005 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0002 0.0003
Echinococcus granulosus myotubularin protein 13 0.0026 0.0049 0.0082
Leishmania major folate/biopterin transporter, putative 0.0031 0.0071 0.0121
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0116 0.0713
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0022 0.0036
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0106 0.0175
Echinococcus multilocularis DCC interacting protein 13 beta 0.0026 0.0049 0.0082
Schistosoma mansoni carbonic anhydrase-related 0.0732 0.3553 0.5866
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0071 0.04
Brugia malayi nuclear hormone receptor 0.0031 0.0073 0.0131
Echinococcus granulosus pdz domain containing protein 0.0026 0.0049 0.0082
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0006
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.0056 0.0099
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0284 0.1006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0481 0.1345
Trichomonas vaginalis protein transport protein sec7, putative 0.0026 0.0049 0.0164
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0284 0.1006
Leishmania major hypothetical protein, conserved 0.0036 0.0094 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0486 0.3297
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0486 0.0802
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0141 0.0246
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Schistosoma mansoni lipoxygenase 0.0362 0.1717 0.2836
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0026 0.0049 0.0129
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0094 0.0169
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0031 0.0071 0.0717
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0031 0.0071 0.0121
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0146 0.0146
Echinococcus granulosus Pleckstrin y 0.0026 0.0049 0.0082
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0071 0.04
Loa Loa (eye worm) PXA domain-containing protein 0.0164 0.0733 0.0733
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0073 0.0121
Schistosoma mansoni goodpasture antigen-binding protein 0.0026 0.0049 0.0082
Echinococcus multilocularis microtubule associated protein 2 0.0725 0.3521 0.5814
Schistosoma mansoni histone deacetylase hda2 0.0153 0.0677 0.1117
Brugia malayi Hemopexin family protein 0.0084 0.0338 0.0602
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.0571 0.102
Brugia malayi Cytohesin 3 0.0026 0.0049 0.0088
Echinococcus granulosus dnaJ subfamily C 6 0.0064 0.0238 0.0393
Mycobacterium ulcerans hypothetical protein 0.0036 0.0094 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Toxoplasma gondii protein kinase domain-containing protein 0.0031 0.0071 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0284 0.0501
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0748 0.2669
Entamoeba histolytica PH domain containing protein kinase, putative 0.0031 0.0071 0.04
Brugia malayi ecdysteroid receptor 0.0031 0.0073 0.0131
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Echinococcus multilocularis histone deacetylase 3 0.0296 0.1389 0.2294
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0486 0.0861
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0071 0.0191
Echinococcus granulosus glutamate NMDA receptor subunit 0.003 0.0069 0.0113
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0204 0.0336
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.1183 0.1183
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0026 0.0049 0.01
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0242 0.0399
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.0544 0.4064
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0031 0.0071 0.0121
Schistosoma mansoni regulator of G protein signaling 0.0164 0.0733 0.1211
Schistosoma mansoni importin beta-1 0.0028 0.0059 0.0098
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1145 0.5604 1
Trichomonas vaginalis centaurin/arf, putative 0.0026 0.0049 0.0164
Trypanosoma cruzi histone deacetylase, putative 0.0153 0.0677 0.1202
Entamoeba histolytica hypothetical protein 0.0038 0.0106 0.0641
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0073 0.0131
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0054 0.0182
Brugia malayi 6-phosphofructokinase 0.0114 0.0486 0.0867
Echinococcus multilocularis geminin 0.0737 0.3577 0.5906
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0025 0.0061
Schistosoma mansoni regulator of G protein signaling 0.0164 0.0733 0.1211
Schistosoma mansoni peptidase Clp (S14 family) 0.0089 0.0362 0.0598
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0031 0.0071 0.0121
Plasmodium falciparum histone deacetylase 1 0.0296 0.1389 0.3905
Onchocerca volvulus 0.0104 0.0433 0.1701
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0197 0.0197
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0165 0.0908
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0116 0.0201
Schistosoma mansoni polycystin 1-related 0.0104 0.0433 0.0716
Schistosoma mansoni hypothetical protein 0.0026 0.0049 0.0082
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0094 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0014 0.0019
Schistosoma mansoni DNA polymerase eta 0.0045 0.0141 0.0233
Brugia malayi Pre-SET motif family protein 0.0443 0.2121 0.3785
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0733 0.2615
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0165 0.0272
Schistosoma mansoni alpha-glucosidase 0.0286 0.1339 0.221
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0284 0.1006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0094 0.0094
Trypanosoma cruzi UDP-galactopyranose mutase 0.0022 0.0025 0.0039
Schistosoma mansoni goodpasture antigen-binding protein 0.0026 0.0049 0.0082
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.004 0.0116 0.0192
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0204 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.1236 0.6057 1
Brugia malayi RNA binding protein 0.0132 0.0571 0.102
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0486 0.0486
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0073 0.0121
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0246
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0094 0.0326
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0222 0.0366
Loa Loa (eye worm) cytohesin 3 0.0026 0.0049 0.0049
Schistosoma mansoni glutamate receptor kainate 0.003 0.0069 0.0113
Brugia malayi Histone deacetylase 1 0.0296 0.1389 0.2479
Brugia malayi probable spectrin beta chain 0.0026 0.0049 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Loa Loa (eye worm) beta-lactamase 0.0036 0.0094 0.0094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0116 0.0317
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1071 0.5241 0.8654
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0036 0.0097 0.016
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0028 0.0056 0.0092
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0026 0.0049 0.0246
Echinococcus multilocularis cpg binding protein 0.0062 0.0226 0.0372
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0486 0.1727
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0165 0.0165
Schistosoma mansoni regulator of G protein signaling 0.0164 0.0733 0.1211
Trypanosoma cruzi hypothetical protein 0.0026 0.0049 0.0082
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0026 0.0049 0.0082
Brugia malayi amine oxidase, flavin-containing family protein 0.0022 0.0025 0.0045
Trypanosoma brucei protein kinase, putative 0.0058 0.0204 0.0357
Schistosoma mansoni hypothetical protein 0.0064 0.0238 0.0393
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.1444 1
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.037 0.1757 0.2901
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0073 0.0131
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0106 0.0175
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0732 0.3553 0.3553
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0217 0.0994 0.1641
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0004 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0164 0.0733 0.1211
Loa Loa (eye worm) hypothetical protein 0.0036 0.0094 0.0094
Mycobacterium ulcerans monoamine oxidase 0.0022 0.0025 0.0078
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0006 0.0004
Loa Loa (eye worm) hypoxia-induced factor 1 0.0158 0.0704 0.0704
Loa Loa (eye worm) hypothetical protein 0.0045 0.0141 0.0141
Entamoeba histolytica Ran family GTPase 0.0021 0.0022 0.0055
Trichomonas vaginalis ran, putative 0.0021 0.0022 0.0066
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0059 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0263 0.0434
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0026 0.0049 0.0246
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0204 0.0357
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0056 0.0092
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0116 0.0403
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0246
Loa Loa (eye worm) doublecortin family protein 0.0104 0.0433 0.0433
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0094 0.0094
Brugia malayi TBC domain containing protein 0.0026 0.0049 0.0088
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0049 0.0088
Brugia malayi hypothetical protein 0.0038 0.0106 0.0189
Echinococcus multilocularis lysosomal alpha glucosidase 0.0332 0.1569 0.259
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0571 0.0944
Brugia malayi beta-lactamase family protein 0.0036 0.0094 0.0169
Leishmania major histone deacetylase, putative 0.0296 0.1389 0.2474
Echinococcus multilocularis survival motor neuron protein 1 0.0508 0.244 0.4029
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 1
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.004 0.0065
Plasmodium falciparum protoporphyrinogen oxidase 0.0022 0.0025 0.0061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.1444 0.5162
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0071 0.047
Echinococcus granulosus regulator of G protein signaling 7 0.0164 0.0733 0.1211
Leishmania major carbonic anhydrase-like protein 0.1145 0.5604 1
Schistosoma mansoni lamin 0.0028 0.0059 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0073 0.0131
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0116 0.0634
Toxoplasma gondii hypothetical protein 0.0051 0.0172 0.0476
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0073 0.0121
Echinococcus granulosus importin subunit beta 1 0.0028 0.0059 0.0098
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.0571 0.0571
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0486 0.3297
Echinococcus multilocularis dynamin 1 0.0026 0.0049 0.0082
Schistosoma mansoni hypothetical protein 0.0038 0.0106 0.0175
Onchocerca volvulus outspread protein homolog 0.0026 0.0049 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1183 0.4228
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0031 0.0071 0.0121
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0217 0.0994 0.1641
Loa Loa (eye worm) histone deacetylase 1 0.0296 0.1389 0.1389
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0486 0.3297
Echinococcus granulosus axis inhibition protein axin 0.0164 0.0733 0.1211
Echinococcus multilocularis regulator of G protein signaling 3 0.0164 0.0733 0.1211
Loa Loa (eye worm) hypothetical protein 0.0104 0.0433 0.0433
Trichomonas vaginalis AGC family protein kinase 0.0031 0.0071 0.0243
Brugia malayi Plekhf2 protein 0.0026 0.0049 0.0088
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0106 0.0189
Schistosoma mansoni rho gtpase activating protein 0.0026 0.0049 0.0082
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0087 0.035 0.0579
Trypanosoma cruzi Protein kinase B 0.0031 0.0071 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0733 0.2615
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0054 0.0182
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.004 0.0103
Brugia malayi Glutamate receptor 2 precursor 0.003 0.0069 0.0122
Onchocerca volvulus 0.0036 0.0094 0.0288
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.024 0.0396
Onchocerca volvulus 0.0104 0.0432 0.1697
Trichomonas vaginalis glutaminase, putative 0.0579 0.2794 1
Brugia malayi histone deacetylase 1 (HD1) 0.0296 0.1389 0.2479
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0073 0.0131
Echinococcus granulosus dna polymerase kappa 0.0019 0.0014 0.0023
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0486 0.3346
Trypanosoma brucei carbonic anhydrase-like protein 0.1145 0.5604 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0362 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0111 0.0183
Brugia malayi beta-lactamase family protein 0.0036 0.0094 0.0169
Brugia malayi phosphofructokinase 0.0114 0.0486 0.0867
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1183 0.4228
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0073 0.0121
Echinococcus multilocularis Pleckstrin y 0.0026 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.0737 0.3577 0.5906
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0028 0.0056 0.029
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0664 0.118
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0054 0.0091
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0368 0.1748 0.1748
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0073
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0368 0.1748 0.2886
Loa Loa (eye worm) histone deacetylase 11 0.0153 0.0677 0.0677
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0026 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0049
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0263 0.0463
Brugia malayi regulator of G-protein signaling egl-10 0.0164 0.0733 0.1309
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0031 0.0071 0.0121
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0036 0.0097 0.016
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0026 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0164 0.0733 0.0733
Brugia malayi Matrixin family protein 0.006 0.0214 0.0382
Echinococcus multilocularis pdz domain containing protein 0.0026 0.0049 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0049 0.0164
Trypanosoma cruzi histone deacetylase, putative 0.0153 0.0677 0.1202
Onchocerca volvulus 0.0028 0.0059 0.014
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0481 0.3591
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0141 0.0246
Entamoeba histolytica PH domain containing protein 0.0026 0.0049 0.0246
Echinococcus granulosus dynamin 1 0.0026 0.0049 0.0082
Toxoplasma gondii hypothetical protein 0.0031 0.0071 0.019

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 3 uM Inhibition of Ca 2+ Influx in cultured rat cerebellar granule cells, mediated by ionotropic glutamate receptor AMPA ChEMBL. 11356106
IC50 (functional) > 3 uM Inhibition of Ca 2+ Influx in cultured rat cerebellar granule cells, mediated by ionotropic glutamate receptor AMPA ChEMBL. 11356106

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.