Detailed information for compound 79535

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 267.329 | Formula: C15H17N5
  • H donors: 0 H acceptors: 2 LogP: 2.39 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCN(CC1)c1nc2cccnc2n2c1ccc2
  • InChi: 1S/C15H17N5/c1-18-8-10-19(11-9-18)15-13-5-3-7-20(13)14-12(17-15)4-2-6-16-14/h2-7H,8-11H2,1H3
  • InChiKey: AJVFZHILGGIADJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic References
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Starlite/ChEMBL References
Rattus norvegicus Serotonin 3 (5-HT3) receptor Starlite/ChEMBL References
Bos taurus Serotonin 2a (5-HT2a) receptor Starlite/ChEMBL References
Sus scrofa Serotonin 1d (5-HT1d) receptor Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_141128 All targets in OG5_141128
Schistosoma japonicum ko:K04165 Oamb gene product from transcript, putative Get druggable targets OG5_141128 All targets in OG5_141128
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133680 All targets in OG5_133680
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum 5-hydroxytryptamine receptor, putative Get druggable targets OG5_133680 All targets in OG5_133680
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Get druggable targets OG5_141128 All targets in OG5_141128
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_141128 All targets in OG5_141128
Brugia malayi Serotonin/octopamine receptor family protein 7 Get druggable targets OG5_141128 All targets in OG5_141128
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Brugia malayi Serotonin receptor Get druggable targets OG5_135430 All targets in OG5_135430
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum 5-hydroxytryptamine receptor 4, putative Serotonin 1d (5-HT1d) receptor   291 aa 292 aa 24.0 %
Echinococcus multilocularis nAChR subunit Serotonin 3 (5-HT3) receptor   483 aa 495 aa 24.2 %
Brugia malayi sulfakinin receptor protein Serotonin 1b (5-HT1b) receptor   386 aa 344 aa 23.3 %
Schistosoma mansoni opsin-like receptor Serotonin 1d (5-HT1d) receptor   291 aa 295 aa 22.0 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein Serotonin 3 (5-HT3) receptor   483 aa 388 aa 21.9 %
Onchocerca volvulus 39S ribosomal protein L13, mitochondrial homolog Serotonin 3 (5-HT3) receptor   483 aa 490 aa 31.0 %
Schistosoma japonicum Neuronal acetylcholine receptor subunit alpha-3 precursor, putative Serotonin 3 (5-HT3) receptor   483 aa 505 aa 21.2 %
Brugia malayi GnHR receptor homolog Serotonin 1b (5-HT1b) receptor   386 aa 335 aa 21.8 %
Echinococcus granulosus dro:myosuppressin receptor Serotonin 1b (5-HT1b) receptor   386 aa 349 aa 18.6 %
Loa Loa (eye worm) hypothetical protein Serotonin 1d (5-HT1d) receptor   291 aa 278 aa 24.1 %
Onchocerca volvulus 26S proteasome non-ATPase regulatory subunit 1 homolog Serotonin 1b (5-HT1b) receptor   386 aa 371 aa 26.1 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative Serotonin 3 (5-HT3) receptor   483 aa 478 aa 25.1 %
Onchocerca volvulus Serotonin 1d (5-HT1d) receptor   291 aa 265 aa 21.9 %
Loa Loa (eye worm) hypothetical protein Serotonin 1d (5-HT1d) receptor   291 aa 301 aa 23.3 %
Onchocerca volvulus Phospholipase d-related homolog Serotonin 1b (5-HT1b) receptor   386 aa 350 aa 18.6 %
Echinococcus granulosus neuropeptide receptor Serotonin 1b (5-HT1b) receptor   386 aa 331 aa 21.8 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 461 aa 24.3 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Serotonin 1b (5-HT1b) receptor   386 aa 332 aa 21.7 %
Brugia malayi acetylcholine receptor alpha subunit precursor, putative Serotonin 3 (5-HT3) receptor   483 aa 463 aa 26.8 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1b (5-HT1b) receptor   386 aa 363 aa 24.0 %
Brugia malayi Tachykinin-like peptides receptor 99D Serotonin 1d (5-HT1d) receptor   291 aa 278 aa 23.4 %
Brugia malayi Serotonin/octopamine receptor family protein 7 Serotonin 1d (5-HT1d) receptor   291 aa 318 aa 32.1 %
Schistosoma japonicum ko:K04255 opsin 4 (melanopsin), putative Serotonin 1b (5-HT1b) receptor   386 aa 359 aa 22.0 %
Echinococcus granulosus g protein coupled receptor Serotonin 1b (5-HT1b) receptor   386 aa 394 aa 20.8 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1b (5-HT1b) receptor   386 aa 310 aa 21.6 %
Loa Loa (eye worm) hypothetical protein Serotonin 1b (5-HT1b) receptor   386 aa 358 aa 25.4 %
Brugia malayi neuropeptide F receptor Serotonin 1d (5-HT1d) receptor   291 aa 281 aa 21.0 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 489 aa 31.3 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog Serotonin 3 (5-HT3) receptor   483 aa 465 aa 27.3 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog Serotonin 3 (5-HT3) receptor   483 aa 482 aa 25.1 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Serotonin 1d (5-HT1d) receptor   291 aa 300 aa 36.0 %
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) Serotonin 3 (5-HT3) receptor   483 aa 503 aa 22.3 %
Echinococcus granulosus orexin receptor type 2 Serotonin 1b (5-HT1b) receptor   386 aa 328 aa 22.3 %
Schistosoma japonicum Rhodopsin, putative Serotonin 1d (5-HT1d) receptor   291 aa 253 aa 21.7 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Serotonin 1d (5-HT1d) receptor   291 aa 349 aa 28.1 %
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor Serotonin 3 (5-HT3) receptor   483 aa 457 aa 26.9 %
Onchocerca volvulus Serotonin 1b (5-HT1b) receptor   386 aa 354 aa 20.1 %
Schistosoma mansoni adenoreceptor Serotonin 1d (5-HT1d) receptor   291 aa 292 aa 28.4 %
Echinococcus multilocularis serotonin receptor Serotonin 1d (5-HT1d) receptor   291 aa 348 aa 23.3 %
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 470 aa 27.7 %
Onchocerca volvulus Forkhead box protein biniou homolog Serotonin 1b (5-HT1b) receptor   386 aa 333 aa 21.3 %
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 457 aa 26.7 %
Schistosoma japonicum Neuronal acetylcholine receptor subunit alpha-9-II precursor, putative Serotonin 3 (5-HT3) receptor   483 aa 457 aa 24.7 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 473 aa 27.5 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type des-2 homolog Serotonin 3 (5-HT3) receptor   483 aa 464 aa 24.8 %
Echinococcus multilocularis serotonin receptor Serotonin 1b (5-HT1b) receptor   386 aa 393 aa 32.3 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 452 aa 29.2 %
Schistosoma mansoni dro/myosuppressin receptor Serotonin 1b (5-HT1b) receptor   386 aa 334 aa 24.0 %
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative Serotonin 3 (5-HT3) receptor   483 aa 514 aa 23.2 %
Brugia malayi neuropeptide F receptor Serotonin 1d (5-HT1d) receptor   291 aa 289 aa 22.8 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 482 aa 23.9 %
Schistosoma mansoni amine GPCR Serotonin 1b (5-HT1b) receptor   386 aa 392 aa 26.0 %
Onchocerca volvulus Serotonin 1d (5-HT1d) receptor   291 aa 291 aa 23.7 %
Onchocerca volvulus Serotonin 1d (5-HT1d) receptor   291 aa 297 aa 21.5 %
Onchocerca volvulus Serotonin 3 (5-HT3) receptor   483 aa 477 aa 26.6 %
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit Serotonin 3 (5-HT3) receptor   483 aa 445 aa 25.6 %
Onchocerca volvulus Large subunit GTPase 1 homolog Serotonin 3 (5-HT3) receptor   483 aa 394 aa 19.3 %
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Serotonin 1d (5-HT1d) receptor   291 aa 284 aa 34.2 %
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 Serotonin 3 (5-HT3) receptor   483 aa 387 aa 25.6 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Serotonin 1b (5-HT1b) receptor   386 aa 355 aa 24.2 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1b (5-HT1b) receptor   386 aa 390 aa 20.8 %
Onchocerca volvulus Cullin-4 homolog Serotonin 1d (5-HT1d) receptor   291 aa 256 aa 25.4 %
Onchocerca volvulus Serotonin 1b (5-HT1b) receptor   386 aa 368 aa 20.7 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1b (5-HT1b) receptor   386 aa 381 aa 22.6 %
Echinococcus granulosus thyrotropin releasing hormone receptor Serotonin 1b (5-HT1b) receptor   386 aa 355 aa 24.2 %
Loa Loa (eye worm) neuropeptide F receptor Serotonin 1d (5-HT1d) receptor   291 aa 318 aa 20.4 %
Brugia malayi Cation transporter family protein 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 404 aa 445 aa 22.0 %
Echinococcus multilocularis neuropeptides capa receptor Serotonin 1b (5-HT1b) receptor   386 aa 381 aa 19.9 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Serotonin 1b (5-HT1b) receptor   386 aa 331 aa 30.8 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog Serotonin 3 (5-HT3) receptor   483 aa 465 aa 27.3 %
Onchocerca volvulus Serotonin 1b (5-HT1b) receptor   386 aa 363 aa 34.4 %
Loa Loa (eye worm) neuropeptide F receptor Serotonin 1d (5-HT1d) receptor   291 aa 260 aa 21.2 %
Schistosoma mansoni biogenic amine (5HT) receptor Serotonin 1b (5-HT1b) receptor   386 aa 344 aa 33.4 %
Brugia malayi Cation transporter family protein 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 484 aa 469 aa 28.6 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Serotonin 1b (5-HT1b) receptor   386 aa 333 aa 37.2 %
Schistosoma mansoni amine GPCR Serotonin 1d (5-HT1d) receptor   291 aa 271 aa 20.7 %
Onchocerca volvulus Serotonin 1d (5-HT1d) receptor   291 aa 376 aa 21.5 %
Schistosoma japonicum Alpha-1A adrenergic receptor, putative Serotonin 1d (5-HT1d) receptor   291 aa 296 aa 32.4 %
Echinococcus granulosus biogenic amine 5HT receptor Serotonin 1d (5-HT1d) receptor   291 aa 359 aa 32.6 %
Echinococcus multilocularis orexin receptor type 2 Serotonin 1b (5-HT1b) receptor   386 aa 328 aa 22.9 %
Echinococcus multilocularis neuropeptide Y receptor Serotonin 1d (5-HT1d) receptor   291 aa 300 aa 22.7 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Serotonin 1b (5-HT1b) receptor   386 aa 356 aa 29.2 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Serotonin 1b (5-HT1b) receptor   386 aa 352 aa 34.7 %
Echinococcus multilocularis somatostatin receptor Serotonin 1d (5-HT1d) receptor   291 aa 287 aa 19.5 %
Loa Loa (eye worm) hypothetical protein Serotonin 1d (5-HT1d) receptor   291 aa 297 aa 25.3 %
Schistosoma mansoni neuropeptide receptor Serotonin 1d (5-HT1d) receptor   291 aa 302 aa 23.5 %
Echinococcus multilocularis dro:myosuppressin receptor Serotonin 1b (5-HT1b) receptor   386 aa 349 aa 18.6 %
Schistosoma japonicum Neuropeptide FF receptor 2, putative Serotonin 1d (5-HT1d) receptor   291 aa 243 aa 21.8 %
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit Serotonin 3 (5-HT3) receptor   483 aa 445 aa 25.4 %
Onchocerca volvulus Serotonin 1d (5-HT1d) receptor   291 aa 319 aa 33.9 %
Echinococcus granulosus g protein coupled receptor Serotonin 1b (5-HT1b) receptor   386 aa 365 aa 23.8 %
Schistosoma mansoni neuropeptide receptor Serotonin 1d (5-HT1d) receptor   291 aa 304 aa 21.1 %
Onchocerca volvulus Diphthamide biosynthesis protein 1 homolog Serotonin 1d (5-HT1d) receptor   291 aa 293 aa 24.9 %
Onchocerca volvulus Serotonin 1b (5-HT1b) receptor   386 aa 381 aa 30.2 %
Echinococcus multilocularis neuropeptide receptor Serotonin 1b (5-HT1b) receptor   386 aa 331 aa 21.4 %
Onchocerca volvulus Serotonin 1d (5-HT1d) receptor   291 aa 289 aa 22.8 %
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 470 aa 26.8 %
Loa Loa (eye worm) acetylcholine receptor alpha subunit Serotonin 3 (5-HT3) receptor   483 aa 484 aa 26.0 %
Onchocerca volvulus Serotonin 1b (5-HT1b) receptor   386 aa 338 aa 34.0 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Serotonin 1b (5-HT1b) receptor   386 aa 320 aa 23.1 %
Onchocerca volvulus Serotonin 1b (5-HT1b) receptor   386 aa 333 aa 21.0 %
Brugia malayi Cation transporter family protein Serotonin 3 (5-HT3) receptor   483 aa 507 aa 28.2 %
Drosophila melanogaster nicotinic Acetylcholine Receptor alpha2 Serotonin 3 (5-HT3) receptor   483 aa 541 aa 25.5 %
Onchocerca volvulus Putative zinc finger protein Serotonin 3 (5-HT3) receptor   483 aa 489 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pre-SET motif family protein 0.0231 0.0963 0.2269
Entamoeba histolytica PH domain containing protein kinase, putative 0.0059 0.0172 0.1241
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0051 0.0134 0.0272
Loa Loa (eye worm) cyclin domain-containing protein 0.0039 0.0081 0.0164
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0073
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis Immunoglobulin 0.0075 0.0248 0.0246
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni nAChR subunit 0.0035 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0097 0.0348 0.071
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0097 0.0348 0.0346
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Echinococcus multilocularis serine:threonine protein kinase N2 0.0032 0.0049 0.0047
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0256 0.1078 0.7801
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0078 0.0182
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0022 0.0001 0.0000068489
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0001 0.0000068489
Giardia lamblia Kinase 0.003 0.004 0.0048
Schistosoma mansoni hypothetical protein 0.0082 0.0279 0.0278
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0121 0.0608
Loa Loa (eye worm) hypothetical protein 0.0459 0.2007 0.4112
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.008 0.0161
Schistosoma mansoni lipoxygenase 0.0022 0.0001 0.0000068489
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1538 0.6959 1
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Echinococcus granulosus low density lipoprotein receptor ldl 0.0022 0.0001 0.0000068489
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0121 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0081 0.0538
Brugia malayi Trypsin-like protease protein 5 0.0045 0.0109 0.0254
Echinococcus granulosus NCK adaptor protein 0.0025 0.0015 0.0013
Echinococcus granulosus glycine receptor subunit alpha 1 0.0087 0.0303 0.0301
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) CAMK protein kinase 0.0039 0.0078 0.0158
Echinococcus multilocularis nervana 2 0.0045 0.0109 0.0108
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus NDR protein kinase 0.0032 0.0049 0.0047
Schistosoma mansoni basigin related 0.0022 0.0001 0.0000068489
Echinococcus granulosus nervana 2 0.0045 0.0109 0.0108
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0119 0.0449 0.0448
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Brugia malayi protein unc-22 0.0039 0.0078 0.0182
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0051 0.0134 0.0704
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Echinococcus granulosus titin 0.0039 0.0078 0.0077
Trypanosoma cruzi cdc2-related kinase 1 0.0103 0.0376 0.2504
Echinococcus granulosus Glutaredoxin protein 5 0.0045 0.0109 0.0108
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0087 0.0303 0.0711
Schistosoma mansoni neuroglian 0.0051 0.0137 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.0039
Onchocerca volvulus 0.0045 0.0109 0.0329
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0087 0.0303 0.0301
Plasmodium falciparum serine/threonine protein kinase, putative 0.0256 0.1078 1
Loa Loa (eye worm) TK/DDR protein kinase 0.003 0.004 0.0079
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.1038 0.1037
Loa Loa (eye worm) hypothetical protein 0.0075 0.0248 0.0505
Echinococcus multilocularis protein dispatched 1 0.0098 0.0349 0.0348
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0119 0.0449 0.0448
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0087 0.0303 0.0301
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.003 0.004 0.0038
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0051 0.0134 0.0314
Echinococcus granulosus activin receptor type 0.0039 0.0081 0.008
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0059 0.0172 0.0981
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0121 0.0097
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0087 0.0303 0.0711
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.004 0.0038
Schistosoma mansoni tyrosine kinase 0.064 0.2837 0.2836
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.006 0.0178 0.0363
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0022 0.0001 0.0000068489
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0039 0.0081 0.0164
Brugia malayi hypothetical protein 0.0035 0.0061 0.014
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0035 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0051 0.0137 0.0136
Echinococcus multilocularis NCK adaptor protein 0.0025 0.0015 0.0013
Schistosoma mansoni serine/threonine RGC 0.003 0.004 0.0038
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0107 0.0393 0.0392
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0035 0.0061 0.014
Echinococcus multilocularis glycine receptor subunit beta 0.0087 0.0303 0.0301
Schistosoma mansoni rab6-interacting 0.0022 0.0001 0.0000068489
Echinococcus granulosus cyclin dependent kinase 5 0.0103 0.0376 0.0375
Echinococcus granulosus tyrosine protein kinase Srms 0.0043 0.0097 0.0096
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0032 0.0049 0.0097
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.004 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0303 0.0711
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0376 0.268
Schistosoma mansoni cell adhesion molecule 0.0039 0.008 0.0078
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.003 0.004 0.0091
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0087 0.0303 0.0711
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0143 0.0142
Echinococcus multilocularis hemicentin 1 0.0039 0.008 0.0078
Schistosoma mansoni cell adhesion molecule 0.0051 0.0137 0.0136
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Loa Loa (eye worm) TK/Met protein kinase 0.003 0.004 0.0079
Echinococcus granulosus Niemann Pick C1 protein 0.0285 0.1207 0.1206
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Schistosoma mansoni nephrin 0.0105 0.0383 0.0382
Brugia malayi Protein kinase domain containing protein 0.0812 0.3627 0.8558
Loa Loa (eye worm) hypothetical protein 0.0114 0.0426 0.0871
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0039 0.0078 0.0158
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0323 0.1382 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0107 0.0393 0.0392
Schistosoma mansoni rab6-interacting 0.0022 0.0001 0.0000068489
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trypanosoma brucei polo-like protein kinase 0.0323 0.1382 1
Schistosoma mansoni septate junction protein 0.0022 0.0001 0.0000068489
Echinococcus granulosus nervana 2 0.0045 0.0109 0.0108
Loa Loa (eye worm) TK protein kinase 0.0107 0.0393 0.0803
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Echinococcus granulosus tyrosine protein kinase Lyn 0.0128 0.049 0.0489
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus 0.0023 0.0009 0.0023
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Schistosoma mansoni cyclin B 0.0039 0.0081 0.008
Brugia malayi plexin A 0.0045 0.0109 0.0254
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus multilocularis transfer RNA-Phe 0.003 0.0037 0.0036
Schistosoma mansoni cyclins 0.0039 0.0081 0.008
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0015 0.0013
Brugia malayi Protein kinase domain containing protein 0.0346 0.1489 0.3511
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0143 0.0335
Brugia malayi serine/threonine protein kinase 6 0.0256 0.1078 0.2543
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0034 0.0059 0.0057
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0054 0.0151 0.1386
Schistosoma mansoni tyrosine kinase 0.064 0.2837 0.2836
Brugia malayi bone morphogenetic protein type 1 receptor 0.003 0.004 0.0091
Schistosoma mansoni serine/threonine-protein kinase 0.0059 0.0172 0.017
Schistosoma mansoni protein kinase 0.0256 0.1078 0.1077
Echinococcus multilocularis epidermal growth factor receptor 0.064 0.2837 0.2836
Loa Loa (eye worm) protein kinase domain-containing protein 0.003 0.004 0.0079
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0039 0.0081 0.008
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1487 0.6727 1
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.1085 0.4879 1
Echinococcus multilocularis glycoprotein Antigen 5 0.0045 0.0109 0.0108
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0035 0.0061 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0084
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0179 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0049 0.0301
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0059 0.0135
Onchocerca volvulus 0.0043 0.0097 0.0293
Trypanosoma brucei rac serine-threonine kinase, putative 0.0082 0.0278 0.1772
Echinococcus multilocularis serine:threonine protein kinase N2 0.0032 0.0049 0.0047
Plasmodium falciparum protein kinase, putative 0.0039 0.0081 0.074
Schistosoma mansoni roundabout 0.0039 0.008 0.0078
Echinococcus multilocularis heat shock protein 70 0.003 0.004 0.0038
Echinococcus granulosus integrin linked protein kinase 0.003 0.004 0.0038
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0087 0.0303 0.0301
Loa Loa (eye worm) hypothetical protein 0.0048 0.0121 0.0246
Loa Loa (eye worm) hypothetical protein 0.0248 0.1038 0.2126
Loa Loa (eye worm) serine/threonine protein kinase 0.003 0.004 0.0079
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.003 0.0058
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Echinococcus granulosus tyrosine kinase 0.0107 0.0393 0.0392
Echinococcus granulosus tyrosine kinase 0.0043 0.0097 0.0096
Echinococcus granulosus defective proboscis extension response 0.0075 0.0248 0.0246
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Echinococcus granulosus RUN 0.0022 0.0001 0.0000068489
Schistosoma mansoni tyrosine-protein kinase fps85d 0.003 0.004 0.0038
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0075 0.0248 0.0246
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0045 0.0109 0.0108
Echinococcus granulosus transmembrane protease serine 3 0.0045 0.0109 0.0108
Schistosoma mansoni adapter molecule crk 0.0025 0.0015 0.0013
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0849 0.38 0.3799
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.003 0.004 0.0038
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.003 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0114 0.0426 0.0871
Echinococcus multilocularis serine:threonine protein kinase 38 0.0032 0.0049 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis cyclin A, putative 0.0039 0.0081 0.0538
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Trypanosoma cruzi cyclin, putative 0.0039 0.0081 0.0311
Schistosoma mansoni cell adhesion molecule 0.0051 0.0137 0.0136
Loa Loa (eye worm) TK/INSR protein kinase 0.0812 0.3627 0.7432
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0029 0.0033 0.0296
Echinococcus granulosus nephrin 0.003 0.0037 0.0036
Trypanosoma cruzi aurora B kinase, putative 0.0256 0.1078 0.7736
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0039 0.008 0.024
Loa Loa (eye worm) AUR protein kinase 0.0256 0.1078 0.2208
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Brugia malayi hypothetical protein 0.0088 0.0305 0.0717
Echinococcus multilocularis growth factor receptor bound protein 2 0.0025 0.0015 0.0013
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0066 0.0598
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0043 0.0097 0.0096
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0045 0.0109 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Loa Loa (eye worm) hypothetical protein 0.0043 0.0097 0.0196
Onchocerca volvulus 0.0045 0.0109 0.0329
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Entamoeba histolytica cyclin, putative 0.0039 0.0081 0.0589
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0022 0.0001 0.0000068489
Plasmodium falciparum cysteine repeat modular protein 2 0.0029 0.0033 0.0296
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.003 0.004 0.0038
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.0226
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0087 0.0303 0.0301
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.064 0.2837 0.2836
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0119 0.0449 0.0448
Trypanosoma cruzi Protein kinase B 0.0059 0.0172 0.0981
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0121 0.0081
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0503 0.3447
Giardia lamblia Kinase, CMGC CDK 0.0103 0.0376 0.254
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0087 0.0303 0.0711
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0001 0.0000068489
Echinococcus multilocularis tyrosine kinase 0.003 0.004 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0414 0.2958
Schistosoma mansoni loxhd1 0.0022 0.0001 0.0000068489
Entamoeba histolytica tyrosin kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni lipoxygenase 0.0061 0.0181 0.018
Echinococcus granulosus raf serine:threonine protein kinase 0.003 0.004 0.0038
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0119 0.0449 0.0448
Echinococcus granulosus tyrosine protein kinase Src42A 0.0119 0.0449 0.0448
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0049 0.0301
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0211 0.0867 0.0866
Loa Loa (eye worm) AGC/AKT protein kinase 0.0082 0.0278 0.0566
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1078 0.7789
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis transfer RNA-Thr 0.003 0.004 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0303 0.0711
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0103 0.0376 0.3278
Schistosoma mansoni polycystin 1-related 0.0022 0.0001 0.0000068489
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0043 0.0097 0.0096
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0087 0.0303 0.0711
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) GABA receptor subunit 0.0053 0.0143 0.0291
Loa Loa (eye worm) hypothetical protein 0.0199 0.0815 0.1668
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0087 0.0303 0.0711
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Plasmodium falciparum protein kinase 5 0.0103 0.0376 0.3477
Loa Loa (eye worm) hypothetical protein 0.0085 0.0293 0.0599
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0073
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0087 0.0303 0.0301
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Brugia malayi Plexin repeat family protein 0.0038 0.0077 0.0178
Echinococcus multilocularis nAChR subunit 0.0087 0.0303 0.0301
Onchocerca volvulus 0.0028 0.003 0.0087
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0087 0.0303 0.0301
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0087 0.0303 0.0301
Schistosoma mansoni septate junction protein 0.0039 0.008 0.0078
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.0038
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.003 0.004 0.0038
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0374 0.1618 0.1617
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0051 0.0134 0.0704
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0045 0.0109 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0001 0.0000068489
Echinococcus multilocularis expressed protein 0.0414 0.18 0.1799
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Entamoeba histolytica protein kinase, putative 0.0082 0.0278 0.2008
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0087 0.0303 0.0301
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0022 0.0001 0.0000068489
Echinococcus granulosus glycine receptor subunit beta 0.0087 0.0303 0.0301
Entamoeba histolytica ankyrin repeat protein 0.003 0.004 0.0288
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0056 0.0055
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0055 0.0153 0.0152
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0143 0.0335
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Echinococcus granulosus expressed protein 0.0414 0.18 0.1799
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.003 0.004 0.0288
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.003 0.004 0.0091
Giardia lamblia Aurora kinase 0.0256 0.1078 0.7747
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0376 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.003 0.004 0.0038
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.004 0.0038
Schistosoma mansoni nck2/grb4 0.0025 0.0015 0.0013
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Echinococcus multilocularis protein KINase family member (kin 25) 0.003 0.004 0.0038
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Loa Loa (eye worm) projectin 0.003 0.0037 0.0073
Echinococcus granulosus beta-adrenergic receptor kinase 0.003 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0001 0.0000068489
Schistosoma mansoni hemicentin 0.003 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0066
Echinococcus multilocularis cpg binding protein 0.003 0.0037 0.0036
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0059 0.0118
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0303 0.0711
Echinococcus granulosus protein kinase c iota type 0.0032 0.0049 0.0047
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0032 0.0049 0.0047
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0075
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0121 0.0283
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0051 0.0137 0.0136
Giardia lamblia G2/mitotic-specific cyclin B 0.0039 0.0081 0.0357
Loa Loa (eye worm) hypothetical protein 0.0459 0.2007 0.4112
Schistosoma mansoni cell adhesion molecule 0.003 0.0037 0.0036
Loa Loa (eye worm) TK/ABL protein kinase 0.0043 0.0097 0.0196
Brugia malayi hypothetical protein 0.0043 0.0097 0.0226
Onchocerca volvulus Putative nachr subunit 0.0087 0.0303 0.0922
Onchocerca volvulus 0.003 0.004 0.0118
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Echinococcus granulosus cyclins 0.0039 0.0081 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Echinococcus granulosus neuroglian 0.0093 0.0326 0.0325
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0061 0.014
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0066 0.5
Entamoeba histolytica hypothetical protein, conserved 0.003 0.004 0.0288
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0107 0.0393 0.0392
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.015 0.112
Loa Loa (eye worm) hypothetical protein 0.0069 0.022 0.0448
Echinococcus granulosus glycine receptor subunit beta 0.0087 0.0303 0.0301
Echinococcus multilocularis cyclin B 0.0039 0.0081 0.008
Schistosoma mansoni titin 0.003 0.0037 0.0036
Onchocerca volvulus 0.003 0.004 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0414 0.2958
Echinococcus granulosus Protein kinase C brain isozyme 0.0032 0.0049 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0066
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.003 0.004 0.0038
Echinococcus granulosus protein tyrosine kinase 0.0587 0.2594 0.2593
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0376 0.268
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Onchocerca volvulus 0.003 0.004 0.0118
Echinococcus granulosus serine threonine protein kinase nrc 0.0054 0.0151 0.0149
Schistosoma mansoni hypothetical protein 0.0399 0.1731 0.173
Onchocerca volvulus 0.003 0.004 0.0118
Brugia malayi Casein kinase II, alpha chain 0.0157 0.062 0.1461
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Echinococcus granulosus roundabout 2 0.0051 0.0137 0.0136
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.003 0.004 0.0079
Trypanosoma brucei cdc2-related kinase 3 0.0103 0.0376 0.2504
Onchocerca volvulus 0.003 0.0037 0.0109
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0051 0.0137 0.0136
Onchocerca volvulus 0.0035 0.0061 0.0182
Schistosoma mansoni nAChR subunit 0.0035 0.0061 0.0059
Entamoeba histolytica tyrosin kinase, putative 0.003 0.004 0.0288
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0121 0.0081
Entamoeba histolytica ankyrin repeat protein 0.003 0.004 0.0288
Echinococcus granulosus cyclins 0.0039 0.0081 0.008
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0132
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.0226
Echinococcus granulosus tyrosine protein kinase Btk29A 0.003 0.004 0.0038
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.003 0.004 0.0091
Schistosoma mansoni hypothetical protein 0.0082 0.0279 0.0278
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0035 0.0061 0.0059
Trichomonas vaginalis STE family protein kinase 0.003 0.004 0.0235
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0066 0.0598
Schistosoma mansoni basigin related 0.0022 0.0001 0.0000068489
Echinococcus granulosus twitchin 0.0102 0.0367 0.0366
Echinococcus multilocularis roundabout 2 0.0051 0.0137 0.0136
Echinococcus granulosus tyrosine protein kinase 0.003 0.004 0.0038
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) acetylcholine receptor protein 0.0035 0.0061 0.0122
Brugia malayi Cation transporter family protein 0.0087 0.0303 0.0711
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.0038
Echinococcus multilocularis serotonin receptor 0.0164 0.0654 0.0653
Schistosoma mansoni serine/threonine-protein kinase 0.0059 0.0172 0.017
Schistosoma mansoni tyrosine kinase 0.0587 0.2594 0.2593
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Giardia lamblia Kinase, NEK 0.003 0.004 0.0048
Trichomonas vaginalis set domain proteins, putative 0.0263 0.1109 0.801
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0137 0.032
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0503 0.0501
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0133 0.0311
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0075 0.0248 0.0246
Echinococcus multilocularis protein kinase c iota type 0.0032 0.0049 0.0047
Echinococcus granulosus activated cdc42 kinase 1 0.003 0.004 0.0038
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0449 0.0448
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0039 0.008 0.0078
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0503 0.0634
Echinococcus granulosus c src tyrosine kinase 0.0055 0.0153 0.0152
Schistosoma mansoni tyrosine kinase 0.0119 0.0449 0.0448
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0449 0.0448
Echinococcus multilocularis protein tyrosine kinase 0.0587 0.2594 0.2593
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis aurora kinase A 0.0256 0.1078 0.1077
Trypanosoma brucei aurora B kinase 0.0256 0.1078 0.7736
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0087 0.0303 0.0618
Schistosoma mansoni tyrosine kinase 0.0609 0.2698 0.2698
Schistosoma mansoni netrin receptor unc5 0.0022 0.0001 0.0000068489
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.0118 0.0276
Loa Loa (eye worm) TK/EPH protein kinase 0.0184 0.0745 0.1525
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0056 0.0055
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0323 0.1382 0.1381
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.003 0.004 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0001 0.0000068489
Schistosoma mansoni plexin 0.0022 0.0003 0.0002
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0056 0.0055
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0303 0.0711
Mycobacterium ulcerans hypothetical protein 0.0048 0.0121 0.0081
Trypanosoma cruzi cdc2-related kinase 1 0.0103 0.0376 0.2504
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0035 0.0061 0.014
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0087 0.0303 0.0301
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Loa Loa (eye worm) AUR protein kinase 0.0256 0.1078 0.2208
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0303 0.0711
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Schistosoma mansoni hypothetical protein 0.0045 0.0109 0.0108
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis activin receptor type 0.0039 0.0081 0.008
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.003 0.004 0.0038
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0001 0.0000068489
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0051 0.0134 0.0704
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.003 0.004 0.0038
Echinococcus multilocularis titin 0.0039 0.0078 0.0077
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0001 0.0000068489
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.004 0.0356
Echinococcus granulosus cyclins 0.0039 0.0081 0.008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.0134 0.0116
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0039 0.0081 0.0458
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Echinococcus multilocularis nervana 2 0.0045 0.0109 0.0108
Onchocerca volvulus 0.0045 0.0109 0.0329
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0121 0.0283
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus 0.0039 0.0081 0.0245
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0077 0.0255 0.0253
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi integrin-linked kinase 0.003 0.004 0.0091
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0025 0.0015 0.0027
Echinococcus granulosus neuroglian 0.0051 0.0137 0.0136
Echinococcus granulosus roundabout 2 0.0051 0.0137 0.0136
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Schistosoma mansoni cyclin B3 0.0039 0.0081 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0029 0.0033 0.0296
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0054 0.0151 0.0149
Schistosoma mansoni survival motor neuron protein 0.0051 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus multilocularis tyrosine protein kinase Abl 0.0055 0.0153 0.0152
Schistosoma mansoni cpg binding protein 0.003 0.0037 0.0036
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0032 0.0049 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0293 0.208
Entamoeba histolytica cysteine surface protein, putative 0.003 0.004 0.0288
Echinococcus granulosus cyclin dependent kinase 0.0103 0.0376 0.0375
Onchocerca volvulus 0.0087 0.0303 0.0922
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0022 0.0001 0.0000068489
Entamoeba histolytica serine/threonine protein kinase, putative 0.0323 0.1382 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0323 0.1382 0.2831
Echinococcus granulosus cyclin dependent kinase 1 0.0103 0.0376 0.0375
Schistosoma mansoni acetylcholine receptor subunit beta 0.0035 0.0061 0.0059
Schistosoma mansoni hypothetical protein 0.0029 0.0033 0.0032
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0035 0.0061 0.0122
Schistosoma mansoni neurotransmitter gated ion channel 0.0035 0.0061 0.0059
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0449 0.0448
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Schistosoma mansoni hypothetical protein 0.0082 0.0279 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Onchocerca volvulus 0.0034 0.0056 0.0167
Onchocerca volvulus 0.0043 0.0097 0.0293
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.003 0.004 0.0235
Schistosoma mansoni cell adhesion molecule 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) TK protein kinase 0.0095 0.0336 0.0685
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Echinococcus multilocularis roundabout 2 0.0127 0.0483 0.0482
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0211 0.0867 0.0866
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus serine/threonine protein kinase 0.0059 0.0172 0.017
Brugia malayi C-terminal src kinase protein 1 0.003 0.004 0.0091
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0121 0.0283
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0081 0.0587
Echinococcus granulosus nAChR subunit 0.0053 0.0143 0.0142
Loa Loa (eye worm) ACC-1 protein 0.0087 0.0303 0.0618
Loa Loa (eye worm) AUR protein kinase 0.0256 0.1078 0.2208
Brugia malayi Protein kinase domain containing protein 0.0082 0.0278 0.0652
Echinococcus multilocularis tyrosine protein kinase 0.003 0.004 0.0038
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0293 0.0292
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.003 0.004 0.0079
Schistosoma mansoni cell adhesion molecule 0.011 0.0405 0.0404
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0538
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Entamoeba histolytica tyrosin kinase, putative 0.003 0.004 0.0288
Giardia lamblia Kinase, CMGC CDK 0.0103 0.0376 0.254
Onchocerca volvulus 0.0035 0.0061 0.0182
Echinococcus multilocularis tyrosine kinase 0.0043 0.0097 0.0096
Echinococcus granulosus roundabout 2 0.0127 0.0483 0.0482
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0323 0.1382 0.1381
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0503 0.0668
Loa Loa (eye worm) TK protein kinase 0.0047 0.0118 0.0239
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0087 0.0303 0.0618
Schistosoma mansoni cell adhesion molecule 0.003 0.0037 0.0036
Echinococcus granulosus plexin a4 0.0045 0.0109 0.0107
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0087 0.0303 0.0618
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0132
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0051 0.0134 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.008 0.0185
Schistosoma mansoni netrin receptor unc5 0.0022 0.0001 0.0000068489
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Echinococcus multilocularis neuroglian 0.0051 0.0137 0.0136
Echinococcus multilocularis 0.028 0.1186 0.1184
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.004 0.0038
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0119 0.0449 0.0448
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.003 0.004 0.0038
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0032 0.0049 0.0047
Schistosoma mansoni basigin related 0.0022 0.0001 0.0000068489
Echinococcus multilocularis expressed conserved protein 0.0187 0.076 0.0758
Brugia malayi hypothetical protein 0.0035 0.0061 0.014
Entamoeba histolytica PH domain containing protein kinase, putative 0.0059 0.0172 0.1241
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0015 0.0031
Echinococcus granulosus epidermal growth factor receptor 0.0945 0.4238 0.4237
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0037 0.0073
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis microtubule associated protein 2 0.22 1 1
Loa Loa (eye worm) SRC-1 0.0119 0.0449 0.0918
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0119 0.0449 0.0448
Echinococcus multilocularis peroxidasin 0.0039 0.008 0.0078
Entamoeba histolytica protein kinase, putative 0.0256 0.1078 0.7801
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0056 0.0055
Onchocerca volvulus 0.003 0.004 0.0118
Toxoplasma gondii AGC kinase 0.0077 0.0257 0.2139
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0035 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Trypanosoma cruzi polo-like protein kinase, putative 0.0323 0.1382 1
Echinococcus granulosus basement membrane specific heparan sulfate 0.0022 0.0001 0.0000068489
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0051 0.0137 0.0136
Onchocerca volvulus Tyrosine kinase homolog 0.0734 0.327 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.003 0.004 0.0091
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0256 0.1078 0.1077
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Onchocerca volvulus 0.003 0.004 0.0118
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0001 0.0000068489
Onchocerca volvulus 0.0053 0.0143 0.0434
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0039 0.0081 0.008
Onchocerca volvulus 0.0051 0.0133 0.0404
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0039 0.0081 0.0311
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0503 0.0501
Echinococcus granulosus casein kinase ii subunit alpha 0.0157 0.062 0.0619
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus granulosus growth factor receptor bound protein 2 0.0025 0.0015 0.0013
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0087 0.0303 0.0618
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0075
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0087 0.0303 0.0301
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0081 0.0308
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.003 0.004 0.0235
Mycobacterium ulcerans hypothetical protein 0.0045 0.0109 0.0063
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.004 0.0356
Echinococcus granulosus tyrosine protein kinase shark 0.0043 0.0097 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0037 0.007 0.0452
Loa Loa (eye worm) hypothetical protein 0.0374 0.1618 0.3315
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0084
Plasmodium falciparum cysteine repeat modular protein 3 0.0029 0.0033 0.0296
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0256 0.1078 0.7801
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0157 0.062 0.1269
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0051 0.0134 0.0971
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.004 0.0356
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus granulosus aurora kinase A 0.0256 0.1078 0.1077
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0103 0.0376 0.2504
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus 0.0038 0.0077 0.023
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Schistosoma mansoni ephrin receptor 0.0151 0.0594 0.0592
Echinococcus granulosus hemicentin 1 0.0039 0.008 0.0078
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0051 0.0134 0.0019
Echinococcus multilocularis transmembrane protease serine 3 0.0045 0.0109 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Brugia malayi Cyclin, N-terminal domain containing protein 0.0039 0.0081 0.0189
Echinococcus multilocularis cyclin dependent kinase 1 0.0103 0.0376 0.0375
Brugia malayi excitatory GABA receptor EXP-1A 0.0087 0.0303 0.0711
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0121 0.0608
Onchocerca volvulus 0.0035 0.0061 0.0182
Echinococcus granulosus muscleblind protein 0.0459 0.2007 0.2006
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.1078 0.1077
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0824 0.3684 0.3683
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0096 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.008 0.0185
Echinococcus multilocularis tyrosine protein kinase otk 0.0039 0.008 0.0078
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0132
Schistosoma mansoni microtubule-associated protein tau 0.22 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0004
Schistosoma mansoni tyrosine kinase 0.0119 0.0449 0.0448
Brugia malayi hypothetical protein 0.0035 0.0061 0.014
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis fibroblast growth factor receptor 4 0.003 0.004 0.0038
Giardia lamblia Cyclin A 0.0039 0.0081 0.0357
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Brugia malayi SH2 domain containing protein 0.0043 0.0097 0.0226
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0034 0.0059 0.0057
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Brugia malayi Muscleblind-like protein 0.0459 0.2007 0.4735
Echinococcus granulosus netrin receptor unc 5 0.0022 0.0001 0.0000068489
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.1038 0.1037
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.003 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0045 0.0109 0.0108
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0087 0.0303 0.0301
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis cyclin dependent kinase 5 0.0103 0.0376 0.0375
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0121 0.0878
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0503 0.449
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Brugia malayi Protein kinase domain containing protein 0.0032 0.0049 0.0112
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis cyclin D, putative 0.0039 0.0081 0.0538
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0079
Echinococcus multilocularis Niemann Pick C1 protein 0.0285 0.1207 0.1206
Schistosoma mansoni neurotransmitter gated ion channel 0.0053 0.0143 0.0142
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Schistosoma mansoni tyrosine protein kinase 0.003 0.004 0.0038
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) TK/RYK protein kinase 0.003 0.004 0.0079
Brugia malayi hypothetical protein 0.0035 0.0061 0.014
Onchocerca volvulus 0.0087 0.0303 0.0922
Plasmodium falciparum cyclin 0.0039 0.0081 0.0743
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.0226
Plasmodium falciparum protein kinase, putative 0.003 0.004 0.0356
Loa Loa (eye worm) plexin A 0.0045 0.0109 0.022
Brugia malayi hypothetical protein 0.0248 0.1038 0.2448
Loa Loa (eye worm) AGC/NDR protein kinase 0.0032 0.0049 0.0097
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0075
Loa Loa (eye worm) hypothetical protein 0.0316 0.135 0.2766
Schistosoma mansoni cell adhesion molecule 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0027
Echinococcus granulosus insulin receptor 0.0812 0.3627 0.3626
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Onchocerca volvulus 0.0043 0.0097 0.0293
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.004 0.0038
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0087 0.0303 0.0301
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Echinococcus granulosus endonuclease reverse transcriptase 0.0029 0.0033 0.0032
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0032 0.0049 0.0047
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0143 0.0335
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Schistosoma mansoni cpg binding protein 0.003 0.0037 0.0036
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0293 0.0292
Echinococcus granulosus tyrosine protein kinase otk 0.0039 0.008 0.0078
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Onchocerca volvulus 0.003 0.0037 0.0109
Entamoeba histolytica protein kinase, putative 0.0032 0.0049 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0051 0.0134 0.0116
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Schistosoma mansoni tyrosine kinase 0.0043 0.0097 0.0096
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus 0.0687 0.3053 0.9337
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0255 0.1072 0.1071
Entamoeba histolytica protein kinase domain containing protein 0.0157 0.062 0.4488
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.0038
Schistosoma mansoni myosin-binding protein-related 0.003 0.0037 0.0036
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0025 0.0015 0.0027
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0293 0.0599
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0055 0.0153 0.0152
Echinococcus granulosus glycine receptor subunit alpha 1 0.0087 0.0303 0.0301
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0119 0.0449 0.0448
Schistosoma mansoni atypical protein kinase C 0.0032 0.0049 0.0047
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0121 0.0878
Schistosoma mansoni hypothetical protein 0.0082 0.0279 0.0278
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni biogenic amine (5HT) receptor 0.0164 0.0654 0.0653
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0035 0.0061 0.0059
Leishmania major protein kinase, putative 0.0039 0.0081 0.0308
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0181 0.018
Echinococcus granulosus biogenic amine 5HT receptor 0.0164 0.0654 0.0653
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni patched 1 0.0085 0.0293 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.003 0.004 0.0092
Onchocerca volvulus 0.0053 0.0143 0.0434
Echinococcus granulosus lachesin 0.0039 0.008 0.0078
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0051 0.0134 0.0704
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0087 0.0303 0.0301
Brugia malayi Protein kinase domain containing protein 0.0103 0.0376 0.0884
Echinococcus multilocularis Immunoglobulin subtype 0.0022 0.0001 0.0000068489
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.004 0.0038
Brugia malayi Raf kinase 0.003 0.004 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Schistosoma mansoni hypothetical protein 0.003 0.004 0.0038
Brugia malayi p70 ribosomal S6 kinase beta 0.0077 0.0257 0.0603
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0087 0.0303 0.0711
Echinococcus multilocularis hemicentin 1 0.0039 0.008 0.0078
Echinococcus multilocularis insulin receptor 0.0812 0.3627 0.3626
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Echinococcus multilocularis tyrosine protein kinase Srms 0.0107 0.0393 0.0392
Entamoeba histolytica hypothetical protein 0.0029 0.0033 0.0241
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0103 0.0376 0.0375
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0103 0.0376 0.0768
Trypanosoma cruzi cyclin, putative 0.0039 0.0081 0.0311
Brugia malayi Tyrosine-protein kinase PR2 0.003 0.004 0.0091
Echinococcus multilocularis Niemann Pick C1 protein 0.0199 0.0815 0.0814
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.0963 0.1971
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Brugia malayi Hr1 repeat family protein 0.0032 0.0049 0.0112
Brugia malayi protein kinase C II. 0.0032 0.0049 0.0112
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Loa Loa (eye worm) trypsin family protein 0.0045 0.0109 0.022
Giardia lamblia Kinase, NEK 0.003 0.004 0.0048
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.003 0.004 0.0079
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Brugia malayi Niemann-Pick C1 protein precursor 0.0199 0.0815 0.1921
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.0069 0.0218 0.0217
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0032 0.0049 0.0047
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Echinococcus granulosus protein kinase c epsilon type 0.0032 0.0049 0.0047
Echinococcus granulosus nAChR subunit 0.0087 0.0303 0.0301
Schistosoma mansoni protein kinase 0.0211 0.0867 0.0866
Onchocerca volvulus 0.0045 0.0109 0.0329
Schistosoma mansoni protein kinase 0.0211 0.0867 0.0866
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.003 0.004 0.0038
Echinococcus multilocularis serotonin receptor 0.0164 0.0654 0.0653
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0066 0.0013
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0103 0.0376 0.2504
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0032 0.0049 0.0097
Schistosoma mansoni septate junction protein 0.0022 0.0001 0.0000068489
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Brugia malayi hypothetical protein 0.003 0.004 0.0091
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0121 0.0608
Leishmania major protein kinase, putative 0.0256 0.1078 0.7736
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis Immunoglobulin 0.0022 0.0001 0.0000068489
Entamoeba histolytica protein kinase, putative 0.0256 0.1078 0.7801
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0039 0.008 0.0078
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0043 0.0097 0.0702
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0137 0.032
Entamoeba histolytica hypothetical protein 0.0029 0.0033 0.0241
Echinococcus granulosus Immunoglobulin subtype 0.0022 0.0001 0.0000068489
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Echinococcus granulosus Immunoglobulin 0.0022 0.0001 0.0000068489
Echinococcus multilocularis muscleblind protein 0.0459 0.2007 0.2006
Entamoeba histolytica protein kinase, putative 0.0038 0.0075 0.054
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0293 0.0292
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0045 0.0109 0.0108
Echinococcus multilocularis neuroglian 0.0093 0.0326 0.0325
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Echinococcus multilocularis nAChR subunit 0.0053 0.0143 0.0142
Trypanosoma cruzi casein kinase II, putative 0.0157 0.062 0.4325
Toxoplasma gondii hypothetical protein 0.003 0.0038 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.0038
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Echinococcus granulosus tyrosine protein kinase Src42A 0.0077 0.0255 0.0253
Brugia malayi serine/threonine-protein kinase plk-2 0.0323 0.1382 0.326
Loa Loa (eye worm) hypothetical protein 0.0088 0.0305 0.0622
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0079
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0121 0.0081
Echinococcus granulosus serine:threonine protein kinase N2 0.0032 0.0049 0.0047
Giardia lamblia Hypothetical protein 0.0039 0.0081 0.0357
Brugia malayi cell division control protein 2 homolog 0.0103 0.0376 0.0884
Entamoeba histolytica receptor protein kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis Mastin 0.0045 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0154
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis ephrin type A receptor 4 A 0.018 0.0726 0.0724
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0035 0.0061 0.0122
Loa Loa (eye worm) hypothetical protein 0.0105 0.0382 0.078
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis activated cdc42 kinase 1 0.003 0.004 0.0038
Schistosoma mansoni tyrosine kinase 0.0812 0.3627 0.3626
Brugia malayi Trypsin family protein 0.0045 0.0109 0.0254
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus granulosus peroxidasin 0.0039 0.008 0.0078
Onchocerca volvulus 0.0121 0.0455 0.1389
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus Serine\/threonine kinase homolog 0.0323 0.1382 0.4225
Echinococcus granulosus protein kinase 0.003 0.004 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0032 0.0049 0.0047
Onchocerca volvulus 0.0087 0.0303 0.0922
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0121 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Loa Loa (eye worm) LGC-31 protein 0.0087 0.0303 0.0618
Giardia lamblia Kinase, PLK 0.0323 0.1382 1
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0087 0.0303 0.0301
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Brugia malayi Trypsin family protein 0.0045 0.0109 0.0254
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Loa Loa (eye worm) TK/ACK protein kinase 0.003 0.004 0.0079
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0051 0.0134 0.0966
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0009 0.0008
Echinococcus multilocularis muscleblind protein 1 0.0459 0.2007 0.2006
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Echinococcus granulosus cpg binding protein 0.003 0.0037 0.0036
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Entamoeba histolytica protein kinase , putative 0.0256 0.1078 0.7801
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0032 0.0049 0.0097
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0157 0.062 0.5748
Onchocerca volvulus 0.0045 0.0109 0.0329
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0001 0.0000068489
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis FL cytokine receptor 0.003 0.004 0.0038
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.003 0.004 0.0235
Echinococcus multilocularis rac serine:threonine kinase 0.0059 0.0172 0.017
Trypanosoma brucei protein kinase, putative 0.0039 0.0081 0.0308
Brugia malayi Trypsin family protein 0.0045 0.0109 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0021 0.002
Echinococcus multilocularis casein kinase ii subunit alpha 0.0157 0.062 0.0619
Toxoplasma gondii aurora kinase 0.0256 0.1078 1
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0538
Toxoplasma gondii CMGC kinase, CK2 family 0.0157 0.062 0.5618
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0056 0.0055
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0538
Onchocerca volvulus 0.0048 0.0121 0.0367
Brugia malayi Furin-like cysteine rich region family protein 0.0945 0.4238 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0654 0.1338
Echinococcus multilocularis natriuretic peptide receptor 1 0.003 0.004 0.0038
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0103 0.0376 0.0768
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0303 0.0711
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.003 0.004 0.0038
Brugia malayi hypothetical protein 0.0045 0.0109 0.0254
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Schistosoma mansoni vesicular amine transporter 0.0075 0.0248 0.0246
Trypanosoma cruzi CYC2-like cyclin, putative 0.0039 0.0081 0.0311
Loa Loa (eye worm) hypothetical protein 0.0051 0.0137 0.0278
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0121 0.0081
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.003 0.004 0.0038
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Onchocerca volvulus 0.0029 0.0033 0.0098
Loa Loa (eye worm) hypothetical protein 0.0048 0.0121 0.0246
Echinococcus multilocularis cyclin dependent kinase 0.0103 0.0376 0.0375
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Schistosoma mansoni plexin 0.0038 0.0077 0.0075
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0001 0.0000068489
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0087 0.0303 0.0301
Schistosoma mansoni nephrin related 0.0022 0.0001 0.0000068489
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0376 0.268
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0181 0.018
Brugia malayi serine/threonine kinase 12 0.0256 0.1078 0.2543
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0087 0.0303 0.0301
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0045 0.0109 0.0108
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.003 0.004 0.0038
Echinococcus granulosus Mastin 0.0045 0.0109 0.0108
Echinococcus granulosus epidermal growth factor receptor 0.064 0.2837 0.2836
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0087 0.0303 0.0711
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.0376 0.2719
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0119 0.0449 0.0448
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0066
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.004 0.0356
Onchocerca volvulus 0.0087 0.0303 0.0922
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0248 0.0505
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.004 0.0038
Schistosoma mansoni tyrosine kinase 0.0043 0.0097 0.0096
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.008 0.0185
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.0812 0.3627 0.3626
Echinococcus granulosus activated cdc42 kinase 1 0.003 0.004 0.0038
Brugia malayi Cyclin, N-terminal domain containing protein 0.0039 0.0081 0.0189
Loa Loa (eye worm) TK/CSK protein kinase 0.003 0.004 0.0079
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0051 0.0137 0.0136
Schistosoma mansoni septate junction protein 0.0039 0.008 0.0078
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Plasmodium vivax protein kinase, putative 0.004 0.0083 0.076
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0087 0.0303 0.0301
Schistosoma mansoni protein tyrosine kinase 0.003 0.004 0.0038
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0132
Loa Loa (eye worm) hypothetical protein 0.0094 0.0335 0.0683
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Cation transporter family protein 0.0087 0.0303 0.0711
Loa Loa (eye worm) hypothetical protein 0.0088 0.0305 0.0622
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0538
Echinococcus granulosus cyclin b3 0.0039 0.0081 0.008
Entamoeba histolytica protein kinase domain containing protein 0.0256 0.1078 0.7801
Entamoeba histolytica protein kinase, putative 0.0082 0.0278 0.2008
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0047 0.0118 0.0117
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0075 0.0248 0.0246
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0087 0.0303 0.0301
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0049 0.0301
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.003 0.004 0.008
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0084
Schistosoma mansoni protein kinase 0.0157 0.062 0.0619
Entamoeba histolytica cyclin family protein 0.0039 0.0081 0.0589
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.0609 0.2698 0.2698
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis cyclin D, putative 0.0039 0.0081 0.0538
Entamoeba histolytica protein kinase, putative 0.0095 0.0336 0.2428
Trypanosoma brucei mitotic cyclin 6 0.0039 0.0081 0.0311
Entamoeba histolytica protein kinase 2, putative 0.0054 0.0151 0.109
Echinococcus multilocularis kinase suppressor of Ras 1 0.003 0.004 0.0038
Leishmania major cyclin 0.0039 0.0081 0.0311
Loa Loa (eye worm) hypothetical protein 0.0088 0.0305 0.0622
Brugia malayi CXXC zinc finger family protein 0.0028 0.003 0.0067
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0056 0.0217
Schistosoma mansoni tyrosine kinase 0.0945 0.4238 0.4237
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.1382 0.1381
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0087 0.0303 0.0301
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0112
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0235
Entamoeba histolytica protein kinase domain containing protein 0.0037 0.0072 0.052
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0037 0.0073
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1078 0.7789
Echinococcus granulosus glycoprotein Antigen 5 0.0045 0.0109 0.0108
Entamoeba histolytica tyrosin kinase, putative 0.0037 0.0072 0.052
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0097
Echinococcus granulosus titin 0.0039 0.0078 0.0077
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Brugia malayi hypothetical protein 0.003 0.004 0.0091
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.003 0.004 0.0038
Schistosoma mansoni hypothetical protein 0.0022 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0037 0.0073
Echinococcus multilocularis serine threonine protein kinase 0.0032 0.0049 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.0039
Echinococcus granulosus tyrosine kinase 0.003 0.004 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0376 0.0375
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0202 0.0829 0.0828
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus 0.0043 0.0097 0.0293
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) hypothetical protein 0.0048 0.0121 0.0246
Loa Loa (eye worm) ACC-1 protein 0.0087 0.0303 0.0618
Echinococcus multilocularis cyclin B3 1 0.0039 0.0081 0.008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Brugia malayi Peroxidasin 0.0039 0.008 0.0185
Brugia malayi serine/threonine-protein kinase 6 0.0256 0.1078 0.2543
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0374 0.1618 0.3817
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) TK/ALK protein kinase 0.003 0.004 0.0079
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0061 0.014
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0199 0.0815 0.5896
Entamoeba histolytica casein kinase, putative 0.0157 0.062 0.4488
Echinococcus multilocularis enteropeptidase 0.0045 0.0109 0.0108
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0256 0.1078 1
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0255 0.1072 0.1071
Brugia malayi ephrin receptor 1 precursor 0.0087 0.0301 0.0707
Brugia malayi Cation transporter family protein 0.0087 0.0303 0.0711
Schistosoma mansoni acetylcholine receptor-related 0.0035 0.0061 0.0059
Echinococcus multilocularis lachesin 0.0039 0.008 0.0078
Brugia malayi protein-tyrosine kinase 0.0107 0.0393 0.0925
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.004 0.0118
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0051 0.0134 0.0099
Schistosoma mansoni peroxidasin 0.0022 0.0001 0.0000068489
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0137 0.032
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0022 0.0001 0.0000068489
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus tyrosine protein kinase Blk 0.0107 0.0393 0.0392
Onchocerca volvulus 0.0039 0.0078 0.0236
Echinococcus granulosus tyrosine protein kinase Src64B 0.0119 0.0449 0.0448
Loa Loa (eye worm) TK/KIN6 protein kinase 0.003 0.004 0.0079
Leishmania major casein kinase II, putative 0.0157 0.062 0.4325
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0081 0.0308
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0449 0.0448
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0087 0.0303 0.0618
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0084
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.004 0.0038
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0022 0.0001 0.0000068489
Schistosoma mansoni hypothetical protein 0.0051 0.0133 0.0132
Brugia malayi Protein kinase domain containing protein 0.0593 0.2624 0.6192
Echinococcus multilocularis tyrosine protein kinase shark 0.0043 0.0097 0.0096
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0032 0.0049 0.0097
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.0038
Echinococcus multilocularis roundabout 2 0.0051 0.0137 0.0136
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0075 0.0248 0.0505
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis tyrosine protein kinase HCK 0.0095 0.0336 0.0334
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0305 0.0717
Schistosoma mansoni neurotransmitter gated ion channel 0.0035 0.0061 0.0059
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Entamoeba histolytica cysteine-rich surface protein, putative 0.0029 0.0033 0.0241
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0087 0.0303 0.0301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.008 0.0185
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Serotonin receptor 0.0573 0.2529 0.5966
Echinococcus multilocularis cyclin b3 0.0039 0.0081 0.008
Brugia malayi CHE-14 protein 0.0085 0.0293 0.069
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0055 0.0153 0.0152
Trypanosoma cruzi cdc2-related kinase 3 0.0103 0.0376 0.2504
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0051 0.0134 0.0748
Echinococcus granulosus cyclins 0.0039 0.0081 0.008
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0051 0.0134 0.0133
Echinococcus granulosus natriuretic peptide receptor 1 0.003 0.004 0.0038
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Echinococcus multilocularis endonuclease reverse transcriptase 0.0029 0.0033 0.0032
Echinococcus multilocularis Immunoglobulin 0.0022 0.0001 0.0000068489
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.003 0.004 0.0038
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Onchocerca volvulus 0.003 0.004 0.0118
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.004 0.0091
Echinococcus granulosus tyrosine protein kinase HCK 0.0095 0.0336 0.0334
Loa Loa (eye worm) AGC/PKN protein kinase 0.0032 0.0049 0.0097
Toxoplasma gondii STE kinase 0.003 0.004 0.0062
Entamoeba histolytica protein kinase, putative 0.0077 0.0257 0.1858
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.008 0.0185
Trichomonas vaginalis cyclin B3, putative 0.0039 0.0081 0.0538
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0084
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Trichomonas vaginalis CAMK family protein kinase 0.003 0.004 0.0235
Giardia lamblia Kinase, CMGC CK2 0.0157 0.062 0.4352
Brugia malayi Trypsin family protein 0.0045 0.0109 0.0254
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.0226
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0824 0.3684 0.3683
Trypanosoma brucei cdc2-related kinase 1 0.0103 0.0376 0.2504
Trichomonas vaginalis protein kinase atn1, putative 0.003 0.004 0.0235
Echinococcus granulosus contactin 0.0051 0.0137 0.0136
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.004 0.0038
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0048 0.0046
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0118 0.0239
Echinococcus multilocularis plexin a4 0.0045 0.0109 0.0107
Echinococcus multilocularis c src tyrosine kinase 0.0055 0.0153 0.0152
Echinococcus granulosus fibroblast growth factor receptor 4 0.003 0.004 0.0038
Trypanosoma cruzi cyclin 6, putative 0.0039 0.0081 0.0311
Echinococcus granulosus dnaJ subfamily B 0.0399 0.1731 0.173
Onchocerca volvulus 0.003 0.004 0.0118
Schistosoma mansoni hypothetical protein 0.003 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0045 0.0109 0.0108
Echinococcus multilocularis cyclins 0.0039 0.0081 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Onchocerca volvulus 0.0043 0.0097 0.0293
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0121 0.0878
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus multilocularis glycine receptor subunit beta 0.0087 0.0303 0.0301
Brugia malayi Probable tyrosine-protein kinase kin-31 0.003 0.004 0.0091
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0081 0.0308
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0087 0.0303 0.0711
Echinococcus granulosus cyclins 0.0039 0.0081 0.008
Schistosoma mansoni serine/threonine kinase 0.0032 0.0049 0.0047
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0087 0.0303 0.0301
Plasmodium falciparum cysteine repeat modular protein 1 0.0029 0.0033 0.0296
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0056 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Trichomonas vaginalis serine-threonine protein kinase, putative 0.003 0.004 0.0235
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0061 0.014
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.004 0.0062
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0077 0.0257 0.0524
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0054 0.0151 0.0826
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Toxoplasma gondii protein kinase domain-containing protein 0.003 0.004 0.0062
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0033 0.0296
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Brugia malayi Tyrosine-protein kinase abl-1 0.0055 0.0153 0.0358
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0047
Loa Loa (eye worm) hypothetical protein 0.0039 0.0081 0.0164
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0814 0.3638 0.7455
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0045 0.0109 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0078 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0449 0.0448
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.0038
Echinococcus granulosus tyrosine protein kinase pr2 0.003 0.004 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Plasmodium vivax unspecified product 0.0157 0.062 0.5748
Echinococcus multilocularis beta adrenergic receptor kinase 0.003 0.004 0.0039
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis tyrosine protein kinase pr2 0.003 0.004 0.0038
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0121 0.0081
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Onchocerca volvulus 0.0087 0.0303 0.0922
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.0038
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Entamoeba histolytica hypothetical protein 0.0053 0.0143 0.1036
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0000068489
Brugia malayi SH2 domain containing protein 0.0043 0.0097 0.0226
Echinococcus granulosus Immunoglobulin 0.0075 0.0248 0.0246
Echinococcus multilocularis twitchin 0.0026 0.0021 0.002
Schistosoma mansoni titin 0.0039 0.008 0.0078
Schistosoma mansoni ephrin receptor 0.0043 0.0097 0.0096
Echinococcus multilocularis Glutaredoxin protein 5 0.0045 0.0109 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1382 1
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0015 0.0013
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0449 0.0448
Echinococcus multilocularis cyclin dependent kinase 1 0.0103 0.0376 0.0375
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0035 0.0061 0.014
Loa Loa (eye worm) hypothetical protein 0.0164 0.0654 0.1338
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Echinococcus multilocularis integrin linked protein kinase 0.003 0.004 0.0038
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0079
Schistosoma mansoni cpg binding protein 0.0028 0.003 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0015 0.0031
Onchocerca volvulus 0.0043 0.0097 0.0293
Echinococcus multilocularis protein kinase 0.003 0.004 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.0323 0.1382 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0047 0.0118 0.0117
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0054 0.0151 0.0149
Entamoeba histolytica receptor protein kinase, putative 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0084
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Toxoplasma gondii protein kinase 0.003 0.004 0.0062
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1538 0.6959 1
Echinococcus granulosus enteropeptidase 0.0045 0.0109 0.0108
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Schistosoma mansoni tyrosine kinase 0.0055 0.0153 0.0152
Echinococcus granulosus glycine receptor subunit alpha 1 0.0087 0.0303 0.0301
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus tyrosine protein kinase ABL1 0.0043 0.0097 0.0096
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0087 0.0303 0.0301
Echinococcus granulosus expressed conserved protein 0.0187 0.076 0.0758
Trypanosoma cruzi cdc2-related kinase 3 0.0103 0.0376 0.2504
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1078 0.7789
Loa Loa (eye worm) hypothetical protein 0.0329 0.1413 0.2895
Brugia malayi Cyclin, N-terminal domain containing protein 0.0039 0.0081 0.0189
Plasmodium falciparum cysteine repeat modular protein 4 0.0029 0.0033 0.0296
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0051 0.0134 0.1233
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Trichomonas vaginalis protein tyrosine kinase, putative 0.003 0.004 0.0235
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.003 0.004 0.0079
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Loa Loa (eye worm) TK/EGFR protein kinase 0.0945 0.4238 0.8684
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0538
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus multilocularis RUN 0.0022 0.0001 0.0000068489
Brugia malayi Pre-SET motif family protein 0.0034 0.0056 0.0129
Plasmodium vivax SET domain protein, putative 0.0034 0.0056 0.0507
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0087 0.0303 0.0301
Entamoeba histolytica cyclin, putative 0.0039 0.0081 0.0589
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0503 0.0634
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.008 0.0161
Schistosoma mansoni tyrosine kinase 0.0609 0.2698 0.2698
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0054 0.0151 0.1386
Schistosoma mansoni kinase 0.0466 0.204 0.2039
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0032 0.0049 0.0047
Brugia malayi Immunoglobulin I-set domain containing protein 0.0814 0.3638 0.8584
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Echinococcus multilocularis Immunoglobulin 0.0075 0.0248 0.0246
Onchocerca volvulus 0.0045 0.0109 0.0329
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0503 0.0634
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.003 0.004 0.0091
Trichomonas vaginalis AGC family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis TK family protein kinase 0.003 0.004 0.0235
Brugia malayi hypothetical protein 0.0035 0.0061 0.014
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0079
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.004 0.0038
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0051 0.0134 0.0971
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0132
Echinococcus multilocularis netrin receptor unc 5 0.0022 0.0001 0.0000068489
Schistosoma mansoni titin 0.0039 0.0078 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Echinococcus multilocularis epidermal growth factor receptor 0.0945 0.4238 0.4237
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0256 0.1078 0.1077
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0503 0.0501
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Onchocerca volvulus 0.0263 0.1109 0.3388
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0053 0.0143 0.0335
Onchocerca volvulus 0.003 0.004 0.0118
Schistosoma mansoni protein kinase 0.003 0.004 0.0038
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0051 0.0137 0.0136
Echinococcus multilocularis protein kinase 0.003 0.004 0.0038
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0256 0.1078 0.7801
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus granulosus ephrin type A receptor 4 A 0.018 0.0726 0.0724
Trypanosoma brucei Casein kinase II 0.0157 0.062 0.4325
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0033 0.0296
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.004 0.0062
Plasmodium vivax protein kinase Crk2 0.0103 0.0376 0.3477
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0029 0.0033 0.0296
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0033 0.0241
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0087 0.0303 0.0711
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Plasmodium falciparum casein kinase 2, alpha subunit 0.0157 0.062 0.5748
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Schistosoma mansoni nAChR subunit 0.0087 0.0303 0.0301
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0538
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0053 0.0143 0.0142
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.1731 0.173
Echinococcus multilocularis protein patched 0.0085 0.0293 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1078 0.7789
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0503 0.0501
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.0226
Echinococcus granulosus Immunoglobulin 0.0022 0.0001 0.0000068489
Loa Loa (eye worm) hypothetical protein 0.0374 0.1618 0.3315
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.008 0.0185
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.003 0.004 0.0038
Echinococcus multilocularis raf serine:threonine protein kinase 0.003 0.004 0.0038
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0538
Brugia malayi SRC-1 0.0119 0.0449 0.1057
Brugia malayi Guanylyl cyclase protein 23 0.003 0.004 0.0091
Plasmodium falciparum protein kinase, putative 0.003 0.004 0.0356
Schistosoma mansoni tyrosine kinase 0.0055 0.0153 0.0152
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0025 0.0015 0.0013
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.003 0.004 0.0038
Entamoeba histolytica cyclin family protein 0.0039 0.0081 0.0589
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0087 0.0303 0.0301
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0103 0.0376 0.0768
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Brugia malayi Prion-like- 0.0039 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.003 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Echinococcus granulosus kinase suppressor of Ras 1 0.003 0.004 0.0038
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0538
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0122
Schistosoma mansoni src-type protein tyrosine kinase-related 0.003 0.004 0.0038
Brugia malayi Fibronectin type III domain containing protein 0.0088 0.0305 0.0717
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0087 0.0303 0.0618
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0291
Onchocerca volvulus 0.0029 0.0033 0.0098
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.004 0.0038
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0045 0.0109 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.062 0.4458
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.022
Echinococcus granulosus protein kinase C gamma type 0.0032 0.0049 0.0047
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0538
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.003 0.004 0.008
Schistosoma mansoni cercarial elastase (S01 family) 0.0045 0.0109 0.0108
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0051 0.0134 0.0922
Schistosoma mansoni protein kinase 0.0039 0.0081 0.008
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0043 0.0097 0.0096
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0161
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.0196
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Loa Loa (eye worm) hypothetical protein 0.0121 0.0455 0.093
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0278 0.1965
Giardia lamblia Protein 21.1 0.003 0.004 0.0048
Plasmodium falciparum conserved protein, unknown function 0.0029 0.0033 0.0296
Loa Loa (eye worm) hypothetical protein 0.0087 0.0303 0.0618
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0066
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0051 0.0134 0.1233
Loa Loa (eye worm) TK/FAK protein kinase 0.0593 0.2624 0.5377
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0079
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.0376 0.2719
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.003 0.004 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Onchocerca volvulus 0.0087 0.0303 0.0922
Brugia malayi Sex muscle abnormal protein 5 0.0025 0.0015 0.0031
Echinococcus granulosus Niemann Pick C1 protein 0.0199 0.0815 0.0814
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0051 0.0134 0.0133
Echinococcus multilocularis protein kinase c epsilon type 0.0032 0.0049 0.0047
Schistosoma mansoni tyrosine-protein kinase fps85d 0.003 0.004 0.0038
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0051 0.0137 0.0278
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0235
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0121 0.0081
Giardia lamblia Kinase, AGC PKA 0.0054 0.0151 0.087
Schistosoma mansoni nephrin 0.0051 0.0137 0.0136
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0056 0.0055
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0091
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.0032 0.0049 0.0112
Echinococcus granulosus cyclin B3 1 0.0039 0.0081 0.008
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0538
Echinococcus granulosus cyclin B 0.0039 0.0081 0.008

Activities

Activity type Activity value Assay description Source Reference
-Log IC50 (binding) = 5.1 Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]-ketanserin as radioligand ChEMBL. 9191957
-Log IC50 (binding) = 6.02 Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]-5-HT as radioligand ChEMBL. 9191957
-Log IC50 (binding) = 6.56 Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]-N-methyl-mesulergine as radioligand ChEMBL. 9191957
-Log IC50 (binding) = 6.61 Binding affinity of the compound towards 5-hydroxytryptamine 1B receptor was measured using [3H]-5-HT as radioligand ChEMBL. 9191957
-Log IC50 (binding) = 7.01 Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]-8-OH-DPAT as radioligand ChEMBL. 9191957
-Log IC50 (binding) = 9.01 Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]-granisetron as radioligand ChEMBL. 9191957
IC50 (binding) = 5.1 Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]-ketanserin as radioligand ChEMBL. 9191957
IC50 (binding) = 6.02 Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]-5-HT as radioligand ChEMBL. 9191957
IC50 (binding) = 6.56 Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]-N-methyl-mesulergine as radioligand ChEMBL. 9191957
IC50 (binding) = 6.61 Binding affinity of the compound towards 5-hydroxytryptamine 1B receptor was measured using [3H]-5-HT as radioligand ChEMBL. 9191957
IC50 (binding) = 7.01 Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]-8-OH-DPAT as radioligand ChEMBL. 9191957
IC50 (binding) = 9.01 Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]-granisetron as radioligand ChEMBL. 9191957
IC50 (binding) = 1 nM Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand ChEMBL. 10543880
IC50 (binding) = 1 nM Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand ChEMBL. 10543880
IC50 (binding) = 5.4 nM The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptor from NG108-15 cells using [3H]-zacopride as radioligand ChEMBL. 10543880
IC50 (binding) = 5.4 nM The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptor from NG108-15 cells using [3H]-zacopride as radioligand ChEMBL. 10543880

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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