Detailed information for compound 89491

Basic information

Technical information
  • TDR Targets ID: 89491
  • Name: 1-(1-adamantyl)ethanamine
  • MW: 179.302 | Formula: C12H21N
  • H donors: 1 H acceptors: 0 LogP: 2.62 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C12CC3CC(C2)CC(C1)C3)N
  • InChi: 1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3
  • InChiKey: UBCHPRBFMUDMNC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Rimantadine
  • 1-(1-adamantyl)ethylamine
  • 13392-28-4
  • Maybridge1_002066
  • C07236
  • BRN 2715740
  • Rimantadina [INN-Spanish]
  • AIDS-106253
  • AIDS106253
  • Rimant & .alpha. IFN
  • Rimantidine & .alpha.IFN
  • Tricyclo(3.3.1.1^3,7)decane-1-methanamine, .alpha.-methyl- & IFN.alpha
  • Enamine_005755
  • 1-tricyclo[3.3.1.1~3,7~]dec-1-ylethanamine
  • NCGC00159491-02
  • NCGC00159491-03
  • 1-(1-Adamantyl)ethylamin
  • 1-ADAMANTANEMETHYLAMINE, alpha-METHYL-
  • IDI1_007990
  • Oprea1_602732
  • Rimantadinum [INN-Latin]
  • Tricyclo(3.3.1.1(sup 3,7))decane-1-methanamine, alpha-methyl-
  • Tricyclo(3.3.1.13,7)decane-1-methanamine, alpha-methyl-
  • alpha-Methyl-1-adamantanemethylamine
  • alpha-Methyladamantanemethylamine
  • AIDS-070976
  • AIDS070976
  • Rimant
  • Tricyclo(3.3.1.1^3,7)decane-1-methanamine, .alpha.-methyl-
  • AIDS-211757
  • AIDS211757
  • AIDS-211758
  • AIDS211758
  • .alpha.-Methyladamantanemethylamine
  • 1-Adamantanemethylamine, .alpha.-methyl-
  • ST5202968

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Influenza A virus Matrix protein 2 References
Trypanosoma cruzi P-type H+-ATPase, putative Curated by TDR Targets No references
Trypanosoma cruzi P-type H+-ATPase, putative Curated by TDR Targets No references
Trypanosoma cruzi P-type H+-ATPase, putative Curated by TDR Targets No references
Homo sapiens solute carrier family 22 (organic cation transporter), member 2 Starlite/ChEMBL References
Homo sapiens solute carrier family 47 (multidrug and toxin extrusion), member 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans adenosine triphosphatase Get druggable targets OG5_127253 All targets in OG5_127253
Candida albicans hypothetical protein Get druggable targets OG5_126647 All targets in OG5_126647
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania braziliensis P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma congolense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania mexicana P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma brucei P-type H+-ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma cruzi proton motive ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma brucei gambiense hypothetical protein, conserved,membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Schistosoma mansoni multidrug resistance protein Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei gambiense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi proton motive ATPase 1, putative Get druggable targets OG5_127253 All targets in OG5_127253
Echinococcus granulosus multidrug and toxin extrusion protein 2 Get druggable targets OG5_126647 All targets in OG5_126647
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma congolense hypothetical protein Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi P-type H+-ATPase, putative Get druggable targets OG5_248502 All targets in OG5_248502
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei gambiense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania infantum P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Schistosoma japonicum Multidrug and toxin extrusion protein 1, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania donovani P-type H+-ATPase 1B, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi P-type H+-ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Leishmania major hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi P-type H+-ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Candida albicans adenosine triphosphatase Get druggable targets OG5_127253 All targets in OG5_127253
Leishmania mexicana P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma brucei gambiense hypothetical protein, conserved,membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania donovani hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma congolense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Schistosoma japonicum Multidrug and toxin extrusion protein 1, putative Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma brucei gambiense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania major P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma cruzi membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei MATE efflux family protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma congolense P-type H+-ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Leishmania infantum P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Neospora caninum ATPase, related Get druggable targets OG5_127253 All targets in OG5_127253
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma congolense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania donovani hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania braziliensis P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei gambiense P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei gambiense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania major hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Echinococcus multilocularis multidrug and toxin extrusion protein 2 Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania infantum P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Toxoplasma gondii E1-E2 ATPase subfamily protein Get druggable targets OG5_127253 All targets in OG5_127253
Leishmania major P-type H -ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma brucei gambiense membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei P-type H+-ATPase, putative Get druggable targets OG5_127253 All targets in OG5_127253
Toxoplasma gondii P-type ATPase PMA1 Get druggable targets OG5_127253 All targets in OG5_127253
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
Candida albicans potential Multi Antimicrobial Extrusion (MATE) family drug/sodium antiporter Get druggable targets OG5_126647 All targets in OG5_126647
Trypanosoma brucei membrane transporter protein, putative Get druggable targets OG5_126647 All targets in OG5_126647
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA P-type H+-ATPase, putative 645 aa 579 aa 22.3 %
Brugia malayi major facilitator superfamily protein solute carrier family 22 (organic cation transporter), member 2 555 aa 550 aa 28.2 %
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 P-type H+-ATPase, putative 898 aa 742 aa 24.7 %
Trypanosoma brucei P-type H+-ATPase, putative P-type H+-ATPase, putative 259 aa 239 aa 83.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0737154 0.0235735 0.288308
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0279476 0.00792816 0.0893366
Echinococcus granulosus sodium channel protein 0.0340814 0.010025 0.0100005
Entamoeba histolytica type A flavoprotein, putative 0.00561787 0.000294922 0.0018897
Brugia malayi WGR domain containing protein 0.00884061 0.00139659 0.00921759
Echinococcus granulosus Protein kinase C brain isozyme 0.0201596 0.0052659 0.00524136
Echinococcus granulosus voltage gated hydrogen channel 1 0.0068986 0.000732728 0.000708079
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0266621 0.00748875 0.0517816
Loa Loa (eye worm) hypothetical protein 0.00498121 0.000077283 0.0000605335
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0820769 0.0264319 0.0303803
Leishmania major hypothetical protein, conserved 0.00561787 0.000294922 0.00171367
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0142323 0.00323968 0.0032151
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0113748 0.00226288 0.0152701
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.00641896 0.000568767 0.000544115
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0266621 0.00748875 0.0517816
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Trypanosoma cruzi hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Onchocerca volvulus 0.0068986 0.000732728 0.00804255
Brugia malayi Cytochrome P450 family protein 0.00917279 0.00151015 0.010011
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0407076 0.0122901 0.0122137
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.00869785 0.00134779 0.0124118
Toxoplasma gondii flavodoxin domain-containing protein 0.00692806 0.000742802 0.00564061
Mycobacterium ulcerans thymidylate synthase 0.156048 0.0517183 0.430138
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.00705803 0.000787229 0.00133071
Brugia malayi hypoxia-induced factor 1 0.0343713 0.0101241 0.0701937
Loa Loa (eye worm) hypothetical protein 0.0737154 0.0235735 0.0270919
Echinococcus multilocularis carboxylesterase 5A 0.0178995 0.0044933 0.00441636
Echinococcus granulosus nAChR subunit 0.0143634 0.00328453 0.00325994
Loa Loa (eye worm) TATA binding protein associated factor 0.0251146 0.00695975 0.0079785
Schistosoma mansoni NADPH flavin oxidoreductase 0.00894129 0.00143101 0.00809978
Schistosoma mansoni transient receptor potential channel 0.0068986 0.000732728 0.00414739
Schistosoma mansoni amine GPCR 0.12315 0.0404724 0.229082
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.00705803 0.000787229 0.00445587
Brugia malayi cation channel family protein 0.0068986 0.000732728 0.00457939
Loa Loa (eye worm) hypothetical protein 0.112305 0.0367651 0.0422682
Loa Loa (eye worm) voltage-gated calcium channel 0.0068986 0.000732728 0.000814594
Echinococcus multilocularis potassium voltage gated channel protein 0.00702188 0.000774871 0.000697641
Brugia malayi Cytochrome P450 family protein 0.0251618 0.00697588 0.0481984
Schistosoma mansoni voltage-gated potassium channel 0.012826 0.00275897 0.0156163
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus tachykinin peptides receptor 99D 0.12315 0.0404724 0.0404488
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0117997 0.00240813 0.0164751
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.12315 0.0404724 0.0403983
Onchocerca volvulus 0.00519113 0.000149044 0.000880534
Loa Loa (eye worm) ACC-1 protein 0.0266621 0.00748875 0.00858709
Leishmania major cytochrome p450-like protein 0.00659567 0.000629176 0.00404854
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0220095 0.00589829 0.00675735
Trypanosoma cruzi Heat shock protein 83, putative 0.0366454 0.0109015 0.0758039
Loa Loa (eye worm) hypothetical protein 0.0238092 0.00651349 0.0074651
Loa Loa (eye worm) hypothetical protein 0.01125 0.00222023 0.0025259
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0328793 0.00961403 0.0110321
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00561854
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) hypothetical protein 0.0737154 0.0235735 0.0270919
Trypanosoma cruzi hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.082362 0.0265293 0.294252
Loa Loa (eye worm) serotonin transporter b 0.243387 0.0815745 0.0938194
Onchocerca volvulus 0.01125 0.00222023 0.0262947
Mycobacterium ulcerans two component sensor kinase MprB 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) CYP4Cod1 0.00917279 0.00151015 0.00170898
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227177
Echinococcus multilocularis g protein coupled receptor 0.12315 0.0404724 0.0403983
Schistosoma mansoni peptide (allatostatin)-like receptor 0.12315 0.0404724 0.229082
Echinococcus granulosus potassium voltage gated channel subfamily D 0.00702188 0.000774871 0.000750223
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.082362 0.0265293 0.218063
Echinococcus granulosus nmda type glutamate receptor 0.0130431 0.00283317 0.00280857
Brugia malayi Pre-B cell enhancing factor precursor 0.0387305 0.0116142 0.0806051
Loa Loa (eye worm) hypothetical protein 0.0823619 0.0265293 0.0304924
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.022964 0.00622458 0.00620007
Treponema pallidum adenosine deaminase 0.082362 0.0265293 0.322767
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0251146 0.00695975 0.0482697
Plasmodium falciparum lysophospholipase, putative 0.0707933 0.0225747 0.24999
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0104602 0.00195022 0.0110386
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.00702188 0.000774871 0.000697641
Loa Loa (eye worm) endoplasmin 0.0366454 0.0109015 0.0125133
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0081147 0.00114844 0.00129286
Plasmodium falciparum plasmepsin II 0.0220095 0.00589829 0.0633427
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0117997 0.00240813 0.0164751
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.00705803 0.000787229 0.00445587
Echinococcus multilocularis mitogen activated protein kinase 11 0.423681 0.143207 0.14314
Treponema pallidum heat shock protein 90 0.0279476 0.00792816 0.0939134
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0113748 0.00226288 0.0140552
Schistosoma mansoni atypical protein kinase C 0.00960204 0.00165688 0.00937828
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.082362 0.0265293 0.317007
Loa Loa (eye worm) hypothetical protein 0.0081147 0.00114844 0.00129286
Schistosoma mansoni poly [ADP-ribose] polymerase 0.00884061 0.00139659 0.00790498
Schistosoma mansoni serine/threonine protein kinase 0.00545379 0.000238831 0.00135183
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.12315 0.0404724 0.229082
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0630373 0.0199233 0.0198476
Trypanosoma cruzi spermidine synthase, putative 0.0371552 0.0110757 0.0770211
Onchocerca volvulus 0.12315 0.0404724 0.495663
Echinococcus granulosus transient receptor potential cation channel 0.0068986 0.000732728 0.000708079
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Trypanosoma brucei membrane transporter protein, putative 0.00565359 0.000307131 0.000374174
Toxoplasma gondii heat shock protein HSP90 0.0366454 0.0109015 0.11934
Echinococcus granulosus carbonic anhydrase II 0.0265031 0.00743438 0.0074099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0714326 0.0227932 0.857587
Brugia malayi kinase, mitochondrial precursor 0.00869785 0.00134779 0.00887663
Loa Loa (eye worm) peptidase family M1 containing protein 0.0956929 0.0310864 0.0357351
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.00884061 0.00139659 0.0161607
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.00869785 0.00134779 0.0155896
Echinococcus granulosus glutamate receptor 2 0.0163871 0.00397629 0.00395172
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0266621 0.00748875 0.0517816
Trypanosoma brucei adenosine kinase, putative 0.00810491 0.0011451 0.00623602
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227177
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus RNA directed DNA polymerase 0.0103194 0.0019021 0.00187748
Treponema pallidum chemotaxis histidine kinase (cheA) 0.00869785 0.00134779 0.0129537
Loa Loa (eye worm) hypothetical protein 0.0178995 0.0044933 0.00514097
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Brugia malayi aspartic protease BmAsp-2, identical 0.00868516 0.00134345 0.00884632
Echinococcus granulosus potassium voltage gated channel subfamily A 0.00702188 0.000774871 0.000750223
Trypanosoma brucei aminopeptidase, putative 0.0251146 0.00695975 0.0469113
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Trichomonas vaginalis DNA topoisomerase II, putative 0.00869785 0.00134779 0.0401331
Onchocerca volvulus 0.12315 0.0404724 0.495663
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0714326 0.0227932 0.129014
Mycobacterium tuberculosis Probable two component sensor kinase 0.00869785 0.00134779 0.00605028
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.00884061 0.00139659 0.00131941
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0185158 0.00470399 0.00467944
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.00641896 0.000568767 0.000491522
Brugia malayi Calcitonin receptor-like protein seb-1 0.0543254 0.0169452 0.117851
Brugia malayi aspartic protease BmAsp-1, identical 0.00868516 0.00134345 0.00884632
Echinococcus granulosus transient receptor potential cation channel 0.0068986 0.000732728 0.000708079
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0113748 0.00226288 0.00218576
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0103383 0.00190857 0.0108029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.12315 0.0404724 0.0403983
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0251146 0.00695975 0.0482697
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.12315 0.0404724 0.0403983
Schistosoma mansoni glutamate receptor NMDA 0.0377729 0.0112869 0.063886
Loa Loa (eye worm) hypothetical protein 0.00868516 0.00134345 0.0015172
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.00869785 0.00134779 0.00605028
Trypanosoma cruzi spermidine synthase, putative 0.0371552 0.0110757 0.0770211
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Loa Loa (eye worm) hypothetical protein 0.00498121 0.000077283 0.0000605335
Trypanosoma cruzi cytochrome P450, putative 0.00917279 0.00151015 0.0102024
Echinococcus multilocularis acetylcholinesterase 0.0178995 0.0044933 0.00441636
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0277117 0.00784754 0.0845846
Onchocerca volvulus 0.0266621 0.00748875 0.0909414
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0407076 0.0122901 0.0122137
Onchocerca volvulus 0.12315 0.0404724 0.495663
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0113748 0.00226288 0.00218576
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Trichomonas vaginalis CMGC family protein kinase 0.0194327 0.00501741 0.180011
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227691
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0068986 0.000732728 0.00477189
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0630373 0.0199233 0.138658
Echinococcus granulosus carbonic anhydrase 0.0081147 0.00114844 0.0011238
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0117997 0.00240813 0.00274207
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Brugia malayi Serotonin receptor 0.318788 0.10735 0.74948
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.12315 0.0404724 0.0465333
Echinococcus granulosus voltage dependent calcium channel 0.0238092 0.00651349 0.00648898
Schistosoma mansoni biogenic amine (5HT) receptor 0.158537 0.0525691 0.297552
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Brugia malayi ORL1-like opioid receptor 0.12315 0.0404724 0.282228
Loa Loa (eye worm) hypothetical protein 0.00549711 0.000253641 0.000263426
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0251146 0.00695975 0.006883
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0224613 0.00605272 0.0456628
Loa Loa (eye worm) hypothetical protein 0.00650175 0.000597069 0.000658524
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.00705803 0.000787229 0.0051526
Loa Loa (eye worm) carboxylesterase 0.0178995 0.0044933 0.00514097
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.12315 0.0404724 0.0403983
Echinococcus multilocularis transfer RNA-Gly 0.00702188 0.000774871 0.000697641
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.022964 0.00622458 0.00614777
Plasmodium vivax aspartyl proteinase, putative 0.00868516 0.00134345 0.0117429
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.00549711 0.000253641 0.000176372
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0113748 0.00226288 0.00218576
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.00519717 0.000151107 0.000515787
Trichomonas vaginalis heat shock protein, putative 0.0237285 0.00648591 0.235987
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Loa Loa (eye worm) neuropeptide F receptor 0.12315 0.0404724 0.0465333
Trypanosoma cruzi hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.245601 0.0823313 0.687881
Loa Loa (eye worm) hypothetical protein 0.0220095 0.00589829 0.00675735
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Entamoeba histolytica heat shock protein 90, putative 0.0366454 0.0109015 0.139287
Loa Loa (eye worm) hypothetical protein 0.00499146 0.0000807884 0.0000645663
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00703584
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.00705803 0.000787229 0.00826703
Echinococcus multilocularis G-protein coupled receptor, putative 0.12315 0.0404724 0.0403983
Schistosoma mansoni nAChR subunit 0.0122987 0.00257871 0.014596
Schistosoma mansoni semaphorin 5-related 0.00498121 0.000077283 0.000437437
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0661519 0.020988 0.0209639
Mycobacterium ulcerans proteasome PrcA 0.245601 0.0823313 0.687881
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.0270919
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.00869785 0.00134779 0.0401331
Brugia malayi G-protein coupled receptor 0.12315 0.0404724 0.282228
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0122987 0.00257871 0.0174767
Trypanosoma brucei heat shock protein 90, putative 0.0366454 0.0109015 0.0744848
Echinococcus multilocularis ryanodine receptor 44f 0.0068986 0.000732728 0.000655496
Schistosoma mansoni poly [ADP-ribose] polymerase 0.00549711 0.000253641 0.00143566
Brugia malayi Cation transporter family protein 0.0328793 0.00961403 0.0666303
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.00702188 0.000774871 0.000697641
Echinococcus granulosus dro:myosuppressin receptor 0.12315 0.0404724 0.0404488
Echinococcus multilocularis glutamate receptor 2 0.0177729 0.00445003 0.00437309
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0068986 0.000732728 0.00804255
Toxoplasma gondii aspartyl protease ASP3 0.00868516 0.00134345 0.0123633
Brugia malayi Dopamine receptor protein 1 0.22972 0.0769026 0.536754
Schistosoma mansoni neuropeptide receptor 0.12315 0.0404724 0.229082
Schistosoma mansoni neuropeptide receptor 0.12315 0.0404724 0.229082
Echinococcus multilocularis g-protein coupled receptor 0.12315 0.0404724 0.0403983
Toxoplasma gondii hypothetical protein 0.0068986 0.000732728 0.00552786
Onchocerca volvulus 0.0714326 0.0227932 0.278733
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.12315 0.0404724 0.282228
Onchocerca volvulus 0.0266621 0.00748875 0.0909414
Echinococcus multilocularis potassium large conductance calcium activated 0.0068986 0.000732728 0.000655496
Toxoplasma gondii heat shock protein 75, putative 0.0150307 0.00351261 0.0366413
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.12315 0.0404724 0.0465333
Schistosoma mansoni pyruvate dehydrogenase 0.00869785 0.00134779 0.00762876
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0265031 0.00743438 0.0515852
Brugia malayi Cytochrome P450 family protein 0.00917279 0.00151015 0.010011
Echinococcus multilocularis nAChR subunit 0.0266621 0.00748875 0.00741204
Loa Loa (eye worm) dihydrofolate reductase 0.186928 0.0622745 0.0716156
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0113748 0.00226288 0.0128083
Loa Loa (eye worm) hypothetical protein 0.017669 0.0044145 0.00505031
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0104602 0.00195022 0.0111223
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0266621 0.00748875 0.00746427
Loa Loa (eye worm) hypothetical protein 0.158537 0.0525691 0.06045
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.00705803 0.000787229 0.0187657
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0104602 0.00195022 0.00187308
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0934516 0.0303202 0.0302453
Echinococcus multilocularis receptor type guanylyl cyclase 0.00650175 0.000597069 0.000519826
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0068986 0.000732728 0.00414739
Loa Loa (eye worm) hypothetical protein 0.0151134 0.00354091 0.00404528
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.00641896 0.000568767 0.000544115
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Echinococcus granulosus carboxylesterase 5A 0.0178995 0.0044933 0.00446875
Echinococcus granulosus neuropeptide receptor 0.521578 0.176672 0.176652
Echinococcus multilocularis methionine synthase reductase 0.0102515 0.00187889 0.00180174
Schistosoma mansoni amine GPCR 0.12315 0.0404724 0.229082
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Schistosoma mansoni transient receptor potential channel 0.0068986 0.000732728 0.00414739
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Loa Loa (eye worm) cytochrome P450 family protein 0.0251618 0.00697588 0.00799707
Echinococcus granulosus poly adp ribose polymerase 2 0.00549711 0.000253641 0.000228981
Echinococcus granulosus NDR protein kinase 0.00641896 0.000568767 0.000544115
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0266621 0.00748875 0.00746427
Mycobacterium ulcerans heat shock protein 90 0.0279476 0.00792816 0.0614529
Schistosoma mansoni adenosine kinase 0.00810491 0.0011451 0.00648149
Echinococcus multilocularis g protein coupled receptor 0.12315 0.0404724 0.0403983
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0113748 0.00226288 0.0154605
Loa Loa (eye worm) hypothetical protein 0.0113748 0.00226288 0.00257496
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Schistosoma mansoni serine/threonine protein kinase 0.0201596 0.0052659 0.029806
Onchocerca volvulus 0.00821922 0.00118417 0.0135819
Echinococcus multilocularis nAChR subunit 0.0143634 0.00328453 0.0032075
Echinococcus multilocularis plexin a4 0.0121218 0.00251824 0.00244114
Onchocerca volvulus DNA topoisomerase 2 homolog 0.00869785 0.00134779 0.0155896
Schistosoma mansoni biogenic amine receptor 0.12315 0.0404724 0.229082
Schistosoma mansoni glutamate receptor NMDA 0.030816 0.0089087 0.050425
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0266621 0.00748875 0.00858709
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0145592 0.00335143 0.116508
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0298168 0.00856715 0.0593161
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.266822 0.0895856 0.625439
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0150307 0.00351261 0.00343559
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0251146 0.00695975 0.0482697
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0150307 0.00351261 0.00348803
Brugia malayi Metabotropic glutamate receptor precursor. 0.0109774 0.00212704 0.014321
Echinococcus granulosus dnaJ subfamily B 0.0762652 0.0244452 0.0244211
Mycobacterium ulcerans amidase 0.0104602 0.00195022 0.0111223
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Loa Loa (eye worm) hypothetical protein 0.00578628 0.000352491 0.000377148
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0185158 0.00470399 0.00538335
Echinococcus multilocularis heat shock protein 90 0.0366454 0.0109015 0.010825
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0220095 0.00589829 0.00582146
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Schistosoma mansoni voltage-gated potassium channel 0.0068986 0.000732728 0.00414739
Toxoplasma gondii transporter, cation channel family protein 0.0238092 0.00651349 0.0702282
Entamoeba histolytica protein kinase, putative 0.00641896 0.000568767 0.00543709
Schistosoma mansoni alpha-1 adrenergic receptor 0.12315 0.0404724 0.229082
Plasmodium falciparum spermidine synthase 0.0371552 0.0110757 0.12129
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0251146 0.00695975 0.0752229
Giardia lamblia Rab geranylgeranyltransferase 0.0117997 0.00240813 0.0365982
Brugia malayi P38 map kinase family protein 2 0.423681 0.143207 1
Trichomonas vaginalis heat shock protein, putative 0.0279476 0.00792816 0.290963
Trypanosoma cruzi amidase, putative 0.0104602 0.00195022 0.0132765
Onchocerca volvulus 0.12315 0.0404724 0.495663
Echinococcus multilocularis protein KINase family member (kin 25) 0.0308721 0.00892788 0.00885128
Echinococcus multilocularis sodium leak channel non selective protein 0.0068986 0.000732728 0.000655496
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Toxoplasma gondii transporter, cation channel family protein 0.0068986 0.000732728 0.00552786
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0737154 0.0235735 0.0235495
Schistosoma mansoni metabotropic glutamate receptor 0.0764958 0.024524 0.138811
Echinococcus multilocularis dnaJ subfamily B 0.0762652 0.0244452 0.0243698
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0104602 0.00195022 0.0111223
Leishmania major heat shock protein, putative 0.0150307 0.00351261 0.0241903
Mycobacterium tuberculosis Conserved protein 0.00869785 0.00134779 0.00605028
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0158693 0.00379931 0.00372232
Brugia malayi Hsp90 protein 0.0150307 0.00351261 0.0240016
Brugia malayi Adenosine kinase-like 0.00810491 0.0011451 0.0074605
Echinococcus multilocularis potassium voltage gated channel protein 0.0112938 0.0022352 0.00215808
Brugia malayi Guanylyl cyclase protein 23 0.00650175 0.000597069 0.00363158
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0291589 0.00834224 0.0082656
Onchocerca volvulus 0.0122987 0.00257871 0.0306934
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0630373 0.0199233 0.219826
Plasmodium falciparum carbonic anhydrase 0.0081147 0.00114844 0.0101807
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0630373 0.0199233 0.11277
Loa Loa (eye worm) hypothetical protein 0.0295615 0.00847986 0.00972732
Echinococcus granulosus ryanodine receptor 44f 0.0068986 0.000732728 0.000708079
Echinococcus multilocularis transient receptor potential cation channel 0.0068986 0.000732728 0.000655496
Trypanosoma cruzi hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.00869785 0.00134779 0.00605028
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.12315 0.0404724 0.229082
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Leishmania major hypothetical protein, conserved 0.0104602 0.00195022 0.0132765
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.00561787 0.000294922 0.00171367
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Leishmania major cAMP-specific phosphodiesterase, putative 0.0113748 0.00226288 0.0154605
Brugia malayi Pepsin A precursor 0.00868516 0.00134345 0.00884632
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0737154 0.0235735 0.133431
Toxoplasma gondii AMP deaminase 0.231015 0.0773453 0.863003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0171889 0.00425039 0.0291562
Toxoplasma gondii DNA topoisomerase 2, putative 0.00869785 0.00134779 0.0124118
Echinococcus multilocularis glycine receptor subunit beta 0.0328793 0.00961403 0.00953748
Mycobacterium ulcerans amidase 0.0104602 0.00195022 0.0111223
Trypanosoma brucei Emopamil binding protein, putative 0.0306758 0.00886077 0.0602095
Onchocerca volvulus 0.0194327 0.00501741 0.0606171
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0707933 0.0225747 0.849257
Echinococcus multilocularis protein kinase c epsilon type 0.0210902 0.00558402 0.00550717
Trichomonas vaginalis heat shock protein, putative 0.0366454 0.0109015 0.404299
Schistosoma mansoni tyrosine kinase 0.00650175 0.000597069 0.00337953
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.00641896 0.000568767 0.000491522
Schistosoma mansoni voltage-gated potassium channel 0.0316466 0.00919264 0.0520322
Giardia lamblia hypothetical protein 0.0113748 0.00226288 0.0315848
Giardia lamblia NADPH oxidoreductase, putative 0.0117129 0.00237844 0.0355737
Brugia malayi G protein-coupled receptor 0.12315 0.0404724 0.282228
Echinococcus granulosus fatty acid amide hydrolase 1 0.0823619 0.0265293 0.0265053
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.00705803 0.000787229 0.00613785
Entamoeba histolytica aminopeptidase, putative 0.0714326 0.0227932 0.293332
Echinococcus granulosus neuropeptides capa receptor 0.12315 0.0404724 0.0404488
Echinococcus multilocularis sex peptide receptor 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) hypothetical protein 0.0169106 0.00415525 0.00475205
Schistosoma mansoni endoplasmin 0.0366454 0.0109015 0.0617044
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0104602 0.00195022 0.0111223
Schistosoma mansoni serine/threonine protein kinase 0.00545379 0.000238831 0.00135183
Echinococcus multilocularis somatostatin receptor 0.12315 0.0404724 0.0403983
Mycobacterium ulcerans spermidine synthase 0.0224613 0.00605272 0.0456628
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0934516 0.0303202 0.0302963
Mycobacterium ulcerans putative regultory protein 0.00869785 0.00134779 0.00605028
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Echinococcus multilocularis cGMP dependent protein kinase 1 0.00545379 0.000238831 0.000161561
Schistosoma mansoni transient receptor potential channel 4 0.0068986 0.000732728 0.00414739
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0109774 0.00212704 0.00241869
Brugia malayi Glutamate receptor 1 precursor 0.0177729 0.00445003 0.030551
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0630373 0.0199233 0.0198992
Brugia malayi hypothetical protein 0.00519113 0.000149044 0.000501372
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0113748 0.00226288 0.0152701
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0150307 0.00351261 0.0435716
Echinococcus multilocularis transfer RNA-Thr 0.0836518 0.0269703 0.026895
Echinococcus multilocularis neuropeptide receptor A26 0.443883 0.150113 0.150047
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0407076 0.0122901 0.0141108
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.00659567 0.000629176 0.00262698
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0171889 0.00425039 0.00417343
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0328793 0.00961403 0.00953748
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus multilocularis serine:threonine protein kinase N2 0.00641896 0.000568767 0.000491522
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0150307 0.00351261 0.0421527
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0103383 0.00190857 0.00216734
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Entamoeba histolytica adenosine deaminase, putative 0.082362 0.0265293 0.34173
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0266621 0.00748875 0.0517816
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0265031 0.00743438 0.0514018
Leishmania major hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0266621 0.00748875 0.0517816
Plasmodium vivax heat shock protein, putative 0.0150307 0.00351261 0.0360361
Loa Loa (eye worm) flavodoxin family protein 0.00561787 0.000294922 0.000310917
Echinococcus multilocularis serotonin receptor 0.158537 0.0525691 0.0524959
Plasmodium vivax PST-A protein 0.0707933 0.0225747 0.249519
Onchocerca volvulus Poor gastrulation protein homolog 0.00578628 0.000352491 0.0033769
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.186928 0.0622745 0.754512
Brugia malayi WGR domain containing protein 0.00549711 0.000253641 0.00123216
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 2.93008 1 1
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Echinococcus multilocularis protein kinase c iota type 0.00960204 0.00165688 0.00157972
Echinococcus multilocularis spermidine synthase 0.0371552 0.0110757 0.0109993
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0964222 0.0313357 0.0312609
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.00519113 0.000149044 0.000143091
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0407076 0.0122901 0.0853271
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Loa Loa (eye worm) hypothetical protein 0.243387 0.0815745 0.0938194
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.12315 0.0404724 0.229082
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0716014 0.0228509 0.129341
Loa Loa (eye worm) hypothetical protein 0.0192155 0.00494317 0.00565852
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.22144 0.074072 0.516978
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0964222 0.0313357 0.0312609
Onchocerca volvulus 0.00650175 0.000597069 0.00637796
Schistosoma mansoni biogenic amine (dopamine) receptor 0.12315 0.0404724 0.229082
Echinococcus multilocularis GPCR, family 3, C terminal 0.00578628 0.000352491 0.000275229
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Trypanosoma cruzi hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Trypanosoma cruzi heat shock protein 85, putative 0.0366454 0.0109015 0.0758039
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0220095 0.00589829 0.0633427
Schistosoma mansoni neurotransmitter gated ion channel 0.0122987 0.00257871 0.014596
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0934516 0.0303202 0.0302963
Trypanosoma cruzi heat shock protein 85, putative 0.0366454 0.0109015 0.0758039
Trypanosoma cruzi Emopamil binding protein, putative 0.0306758 0.00886077 0.061549
Brugia malayi Protein kinase domain containing protein 0.00641896 0.000568767 0.00343385
Schistosoma mansoni hypothetical protein 0.12315 0.0404724 0.229082
Echinococcus granulosus glutamate receptor subunit protein glur 0.00657698 0.000622786 0.000598135
Schistosoma mansoni hypothetical protein 0.0371365 0.0110693 0.0626546
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0158693 0.00379931 0.00372232
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.00869785 0.00134779 0.00887663
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0143634 0.00328453 0.0185911
Mycobacterium tuberculosis Possible lysophospholipase 0.0736072 0.0235366 0.192866
Schistosoma mansoni hypothetical protein 0.0171889 0.00425039 0.0240581
Brugia malayi p70 ribosomal S6 kinase beta 0.00641896 0.000568767 0.00343385
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0714326 0.0227932 0.158872
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Loa Loa (eye worm) hypothetical protein 0.0135025 0.00299022 0.00341173
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Plasmodium falciparum transporter, putative 0.0737154 0.0235735 0.26117
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Trypanosoma cruzi C-8 sterol isomerase, putative 0.146825 0.0485655 0.3389
Echinococcus granulosus AMP deaminase 2 0.231015 0.0773453 0.0773226
Mycobacterium ulcerans aminopeptidase N PepN 0.0714326 0.0227932 0.186607
Onchocerca volvulus 0.12315 0.0404724 0.495663
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.00705803 0.000787229 0.00373261
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0277117 0.00784754 0.987747
Toxoplasma gondii aminopeptidase N protein 0.0251146 0.00695975 0.0752229
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0117997 0.00240813 0.00238352
Schistosoma mansoni voltage-gated potassium channel 0.0068986 0.000732728 0.00414739
Brugia malayi Transient-receptor-potential like protein 0.0068986 0.000732728 0.00457939
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0251146 0.00695975 0.0393936
Giardia lamblia NADPH oxidoreductase, putative 0.0117129 0.00237844 0.0355737
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Entamoeba histolytica adenosine deaminase, putative 0.082362 0.0265293 0.34173
Schistosoma mansoni sodium/chloride dependent transporter 0.0737154 0.0235735 0.133431
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Echinococcus granulosus hypothetical protein 0.0068986 0.000732728 0.000708079
Loa Loa (eye worm) hypothetical protein 0.00868516 0.00134345 0.0015172
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Echinococcus multilocularis thymidylate synthase 0.156048 0.0517183 0.051645
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus sex peptide receptor 0.12315 0.0404724 0.0404488
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081147 0.00114844 0.00748386
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0104602 0.00195022 0.0111223
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0964222 0.0313357 0.0312609
Brugia malayi Protein kinase domain containing protein 0.00519717 0.000151107 0.000515787
Echinococcus multilocularis serine:threonine protein kinase N2 0.017669 0.0044145 0.00433755
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0182734 0.00462111 0.049048
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus short transient receptor potential channel 6 0.0068986 0.000732728 0.000708079
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0279476 0.00792816 1
Plasmodium falciparum DNA gyrase subunit B 0.00869785 0.00134779 0.0124118
Loa Loa (eye worm) hypothetical protein 0.243387 0.0815745 0.0938194
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Entamoeba histolytica PH domain containing protein kinase, putative 0.0132641 0.00290873 0.0357489
Trypanosoma cruzi heat shock protein 90, putative 0.0216148 0.00576334 0.0399124
Loa Loa (eye worm) CAMK/PKD protein kinase 0.00519717 0.000151107 0.000145465
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.423681 0.143207 1
Loa Loa (eye worm) hypothetical protein 0.0144331 0.00330834 0.00377772
Echinococcus multilocularis transient receptor potential cation channel 0.0068986 0.000732728 0.000655496
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0964222 0.0313357 0.0313118
Echinococcus granulosus serine:threonine protein kinase N2 0.00641896 0.000568767 0.000544115
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.022964 0.00622458 0.00620007
Toxoplasma gondii AGC kinase 0.00641896 0.000568767 0.00369276
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0266621 0.00748875 0.00741204
Echinococcus granulosus glutamate receptor NMDA 0.00785192 0.00105862 0.00103398
Brugia malayi Amidase family protein 0.0104602 0.00195022 0.0130856
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0103383 0.00190857 0.0108029
Entamoeba histolytica AMP deaminase, putative 0.231015 0.0773453 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0113748 0.00226288 0.0152701
Trypanosoma cruzi cytochrome p450-like protein, putative 0.00659567 0.000629176 0.00404854
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0158693 0.00379931 0.0248031
Schistosoma mansoni glutamate receptor kainate 0.0177729 0.00445003 0.0251881
Echinococcus granulosus voltage gated potassium channel 0.012826 0.00275897 0.00273437
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0266621 0.00748875 0.0517816
Echinococcus granulosus nmda type glutamate receptor 0.0144289 0.00330691 0.00328232
Toxoplasma gondii leucyl aminopeptidase LAP 0.0277117 0.00784754 0.0851593
Echinococcus granulosus heat shock protein 90 0.0279476 0.00792816 0.00790369
Plasmodium falciparum plasmepsin III 0.00868516 0.00134345 0.0123633
Leishmania major hypothetical protein, conserved 0.082362 0.0265293 0.18497
Brugia malayi AKH receptor 0.12315 0.0404724 0.282228
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0226538
Schistosoma mansoni ATP-binding cassette transporter 0.0177856 0.00445439 0.0252127
Echinococcus multilocularis voltage gated potassium channel 0.00702188 0.000774871 0.000697641
Loa Loa (eye worm) glutamate receptor 0.0109774 0.00212704 0.00241869
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0068986 0.000732728 0.00457939
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0103383 0.00190857 0.00183142
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Plasmodium falciparum AMP deaminase, putative 0.231015 0.0773453 0.863003
Echinococcus multilocularis neuropeptide Y receptor 0.12315 0.0404724 0.0403983
Onchocerca volvulus Tyrosine kinase homolog 0.0169432 0.0041664 0.050175
Echinococcus granulosus 7TM GPCR rhodopsin 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) hypoxia-induced factor 1 0.0343713 0.0101241 0.0116189
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0185158 0.00470399 0.0323253
Echinococcus multilocularis dihydrofolate reductase 0.186928 0.0622745 0.062202
Echinococcus granulosus atrial natriuretic peptide receptor 0.00519113 0.000149044 0.000124381
Echinococcus granulosus biogenic amine 5HT receptor 0.258517 0.0867465 0.086724
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Schistosoma mansoni single-minded 0.0111054 0.00217078 0.012287
Echinococcus granulosus neuropeptide Y receptor 0.12315 0.0404724 0.0404488
Echinococcus granulosus short transient receptor potential channel 6 0.0068986 0.000732728 0.000708079
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0185158 0.00470399 0.00462706
Entamoeba histolytica type A flavoprotein, putative 0.00561787 0.000294922 0.0018897
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0714326 0.0227932 0.158872
Mycobacterium tuberculosis Probable sensor protein KdpD 0.00869785 0.00134779 0.00605028
Schistosoma mansoni serine/threonine kinase 0.00641896 0.000568767 0.00321934
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.12315 0.0404724 0.0404488
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Trypanosoma cruzi heat shock protein 85, putative 0.0366454 0.0109015 0.0758039
Schistosoma mansoni calcium-activated potassium channel 0.0068986 0.000732728 0.00414739
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0113748 0.00226288 0.0154605
Echinococcus granulosus alpha 1A adrenergic receptor 0.12315 0.0404724 0.0404488
Echinococcus multilocularis serotonin receptor 0.158537 0.0525691 0.0524959
Brugia malayi Hr1 repeat family protein 0.00641896 0.000568767 0.00343385
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.00561787 0.000294922 0.000627782
Echinococcus granulosus glycine receptor subunit beta 0.0328793 0.00961403 0.0095896
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0113748 0.00226288 0.0154605
Plasmodium falciparum M17 leucyl aminopeptidase 0.0174667 0.00434535 0.0459616
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0964222 0.0313357 0.0312609
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus mitogen activated protein kinase 14 0.423681 0.143207 0.143185
Schistosoma mansoni AMP deaminase 0.231015 0.0773453 0.43779
Echinococcus multilocularis aminopeptidase N 0.142011 0.0469198 0.0468462
Trichomonas vaginalis adenosine deaminase, putative 0.082362 0.0265293 1
Plasmodium falciparum heat shock protein 90 0.0366454 0.0109015 0.11934
Leishmania major sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00703584
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.00659567 0.000629176 0.00404854
Loa Loa (eye worm) hypothetical protein 0.00519113 0.000149044 0.000143091
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.00869785 0.00134779 0.00605028
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0661519 0.020988 0.0209124
Loa Loa (eye worm) AGC/PKG protein kinase 0.00545379 0.000238831 0.000246388
Loa Loa (eye worm) hypothetical protein 0.146825 0.0485655 0.055844
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0103383 0.00190857 0.00188395
Brugia malayi Peptidase family M1 containing protein 0.0251146 0.00695975 0.0480856
Brugia malayi cytochrome P450 0.00659567 0.000629176 0.0038559
Echinococcus granulosus metabotropic glutamate receptor 5 0.0192155 0.00494317 0.00491863
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.00869785 0.00134779 0.00605028
Trypanosoma cruzi hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Loa Loa (eye worm) TYRA-2 protein 0.12315 0.0404724 0.0465333
Plasmodium falciparum phosphodiesterase delta, putative 0.0113748 0.00226288 0.0226538
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.266822 0.0895856 0.624904
Loa Loa (eye worm) hypothetical protein 0.0836518 0.0269703 0.0309997
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Trichomonas vaginalis conserved hypothetical protein 0.0113748 0.00226288 0.0750144
Loa Loa (eye worm) hypothetical protein 0.0205806 0.00540981 0.00619536
Echinococcus granulosus serotonin receptor 0.12315 0.0404724 0.0404488
Onchocerca volvulus 0.12315 0.0404724 0.495663
Leishmania major protein kinase, putative 0.00833993 0.00122544 0.00821362
Brugia malayi Endoplasmin precursor 0.0366454 0.0109015 0.0756251
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0117997 0.00240813 0.0164751
Entamoeba histolytica DNA topoisomerase II, putative 0.00869785 0.00134779 0.0155285
Loa Loa (eye worm) hypothetical protein 0.046318 0.014208 0.0163172
Trypanosoma cruzi DNA topoisomerase II, putative 0.00869785 0.00134779 0.0090683
Echinococcus granulosus activated cdc42 kinase 1 0.0836518 0.0269703 0.0269463
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0251146 0.00695975 0.0079785
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227691
Echinococcus multilocularis G protein coupled receptor 139 0.521578 0.176672 0.176609
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Loa Loa (eye worm) cytochrome P450 family protein 0.00917279 0.00151015 0.00170898
Loa Loa (eye worm) cytochrome P450 family protein 0.00917279 0.00151015 0.00170898
Echinococcus multilocularis 0.00659567 0.000629176 0.000551935
Loa Loa (eye worm) voltage-gated potassium channel 0.0068986 0.000732728 0.000814594
Schistosoma mansoni serine/threonine protein kinase 0.0210902 0.00558402 0.0316067
Leishmania major cytochrome p450-like protein 0.00917279 0.00151015 0.0102024
Loa Loa (eye worm) carbonic anhydrase 3 0.0265031 0.00743438 0.00852455
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Mycobacterium ulcerans amidase 0.0104602 0.00195022 0.0111223
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0277117 0.00784754 0.0607741
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0328793 0.00961403 0.0544173
Leishmania major protein kinase, putative 0.00545379 0.000238831 0.00132186
Leishmania major hypothetical protein, conserved 0.0068986 0.000732728 0.00477189
Echinococcus multilocularis potassium voltage gated channel protein 0.0068986 0.000732728 0.000655496
Loa Loa (eye worm) hypothetical protein 0.0103194 0.0019021 0.00215991
Loa Loa (eye worm) hypothetical protein 0.00571103 0.000326768 0.000347555
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0122987 0.00257871 0.00250162
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.00657698 0.000622786 0.000545545
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0265031 0.00743438 0.0514018
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0407076 0.0122901 0.0122657
Loa Loa (eye worm) hypothetical protein 0.0823412 0.0265222 0.0304843
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Brugia malayi Cation transporter family protein 0.0266621 0.00748875 0.0517816
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.00549711 0.000253641 0.00142531
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0543254 0.0169452 0.0194663
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus carbonic anhydrase 0.0081147 0.00114844 0.0011238
Plasmodium falciparum nitric oxide synthase, putative 0.0158693 0.00379931 0.0398502
Loa Loa (eye worm) hypothetical protein 0.0371365 0.0110693 0.0127064
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0707933 0.0225747 0.849257
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0117997 0.00240813 0.080551
Trypanosoma brucei AMP deaminase, putative 0.231015 0.0773453 0.53928
Brugia malayi latrophilin 2 splice variant baaae 0.0371365 0.0110693 0.076798
Echinococcus granulosus glutamate receptor ionotropic kainate 0.00657698 0.000622786 0.000598135
Leishmania major monoglyceride lipase, putative 0.0707933 0.0225747 0.157345
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Echinococcus granulosus hyperpolarization activated cyclic 0.0103383 0.00190857 0.00188395
Leishmania major extracellular receptor, putative 0.00519113 0.000149044 0.000694663
Toxoplasma gondii hypothetical protein 0.0068986 0.000732728 0.00552786
Echinococcus granulosus cGMP dependent protein kinase 1 0.00545379 0.000238831 0.000214171
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0103383 0.00190857 0.00183142
Trypanosoma cruzi hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Loa Loa (eye worm) hypothetical protein 0.00702188 0.000774871 0.000863077
Loa Loa (eye worm) G-protein coupled receptor 0.12315 0.0404724 0.0465333
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.12315 0.0404724 0.229082
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0820769 0.0264319 0.184131
Trypanosoma cruzi Aminopeptidase M1, putative 0.0714326 0.0227932 0.158872
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0308721 0.00892788 0.00890344
Loa Loa (eye worm) hypothetical protein 0.124604 0.0409693 0.047105
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Mycobacterium tuberculosis Possible two component sensor kinase 0.00869785 0.00134779 0.00605028
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.00869785 0.00134779 0.0090683
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Brugia malayi hypothetical protein 0.0068986 0.000732728 0.00457939
Onchocerca volvulus 0.00868516 0.00134345 0.0155363
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0291589 0.00834224 0.009569
Plasmodium vivax plasmepsin IV, putative 0.0220095 0.00589829 0.0627543
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Mycobacterium ulcerans aminopeptidase N PepN 0.0251146 0.00695975 0.0532995
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) heat shock protein 90 0.0366454 0.0109015 0.0125133
Onchocerca volvulus 0.12315 0.0404724 0.495663
Trichomonas vaginalis protein phosphatase 2C delta isoform, putative 0.0151187 0.0035427 0.123799
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.186928 0.0622745 0.519015
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0113748 0.00226288 0.00257496
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) aspartic protease BmAsp-1 0.00868516 0.00134345 0.0015172
Echinococcus granulosus sodium and chloride dependent glycine 0.0737154 0.0235735 0.0235495
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0113748 0.00226288 0.0128083
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0714326 0.0227932 0.857587
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Schistosoma mansoni serine/threonine protein kinase 0.00641896 0.000568767 0.00321934
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus single minded 2 0.0107069 0.00203457 0.00200996
Brugia malayi G-protein coupled receptor 0.12315 0.0404724 0.282228
Schistosoma mansoni voltage-dependent calcium channel 0.0068986 0.000732728 0.00414739
Loa Loa (eye worm) hypothetical protein 0.243387 0.0815745 0.0938194
Trypanosoma cruzi hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Entamoeba histolytica AMP deaminase, putative 0.231015 0.0773453 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) hypothetical protein 2.54758 0.869246 1
Trypanosoma cruzi aminopeptidase, putative 0.0251146 0.00695975 0.0482697
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Brugia malayi plexin A 0.0121218 0.00251824 0.0170542
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.00869785 0.00134779 0.00879553
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0068986 0.000732728 0.00457939
Echinococcus granulosus transient receptor potential cation channel 0.0068986 0.000732728 0.000708079
Brugia malayi hypothetical protein 0.0122987 0.00257871 0.0174767
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0707933 0.0225747 0.290501
Leishmania major cytochrome P450 reductase, putative 0.0145592 0.00335143 0.0230644
Loa Loa (eye worm) hypothetical protein 0.0109774 0.00212704 0.00241869
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0215059 0.00572613 0.00655928
Echinococcus multilocularis adenosine kinase 0.00810491 0.0011451 0.0010679
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0104602 0.00195022 0.0203655
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Trichomonas vaginalis protein phosphatase 2C, putative 0.0151187 0.0035427 0.123799
Brugia malayi Cyclic-nucleotide gated cation channel 0.0103383 0.00190857 0.0127946
Trypanosoma brucei MATE efflux family protein, putative 0.00565359 0.000307131 0.000374174
Echinococcus multilocularis neuropeptide receptor 0.521578 0.176672 0.176609
Brugia malayi Plexin repeat family protein 0.00997267 0.00178358 0.0119213
Trichomonas vaginalis conserved hypothetical protein 0.0113748 0.00226288 0.0750144
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.156048 0.0517183 0.292736
Brugia malayi voltage-dependent calcium channel 0.0068986 0.000732728 0.00457939
Schistosoma mansoni voltage-gated potassium channel 0.0316466 0.00919264 0.0520322
Plasmodium vivax flavodoxin domain containing protein 0.0145592 0.00335143 0.0342311
Echinococcus granulosus acetylcholinesterase 0.0178995 0.0044933 0.00446875
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0158693 0.00379931 0.0266906
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0407076 0.0122901 0.0122657
Schistosoma mansoni cathepsin D (A01 family) 0.0560097 0.017521 0.0991723
Brugia malayi excitatory GABA receptor EXP-1A 0.0266621 0.00748875 0.0517816
Plasmodium falciparum DNA topoisomerase 2 0.00869785 0.00134779 0.0124118
Onchocerca volvulus 0.0737154 0.0235735 0.288308
Brugia malayi Spermidine synthase 0.0371552 0.0110757 0.0768426
Echinococcus granulosus glutamate receptor 2 0.022964 0.00622458 0.00620007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0068986 0.000732728 0.00804255
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0306758 0.00886077 0.061549
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0512376 0.0158897 0.59444
Schistosoma mansoni serine/threonine protein kinase 0.0194327 0.00501741 0.0283995
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.12315 0.0404724 0.0404488
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0117997 0.00240813 0.0150713
Schistosoma mansoni voltage-gated potassium channel 0.0068986 0.000732728 0.00414739
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0113748 0.00226288 0.0154605
Schistosoma mansoni hypothetical protein 0.00578628 0.000352491 0.00199517
Onchocerca volvulus 0.12315 0.0404724 0.495663
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0737154 0.0235735 0.164161
Schistosoma mansoni protein kinase C mu 0.00519717 0.000151107 0.000855297
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.00869785 0.00134779 0.0076539
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.12315 0.0404724 0.229082
Toxoplasma gondii hypothetical protein 0.0081147 0.00114844 0.0101807
Loa Loa (eye worm) hypothetical protein 0.00519113 0.000149044 0.000143091
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Loa Loa (eye worm) hypothetical protein 0.00519113 0.000149044 0.000143091
Leishmania major hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Mycobacterium leprae Probable two component sensor kinase MprB 0.00869785 0.00134779 0.00879553
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.00659567 0.000629176 0.00404854
Brugia malayi larval opioid receptor 0.12315 0.0404724 0.282228
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0823619 0.0265293 0.0264541
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0266621 0.00748875 0.00858709
Schistosoma mansoni carbonic anhydrase-related 0.0081147 0.00114844 0.00650042
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) hypothetical protein 0.0753929 0.024147 0.0277517
Echinococcus granulosus potassium voltage gated channel subfamily C 0.00702188 0.000774871 0.000750223
Loa Loa (eye worm) hypothetical protein 0.0081147 0.00114844 0.00129286
Echinococcus granulosus leucine aminopeptidase protein 0.0277117 0.00784754 0.00782306
Schistosoma mansoni hypothetical protein 0.00498121 0.000077283 0.000437437
Loa Loa (eye worm) voltage-dependent calcium channel 0.0238092 0.00651349 0.0074651
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122987 0.00257871 0.0174767
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0714326 0.0227932 0.158872
Trypanosoma cruzi extracellular receptor, putative 0.00519113 0.000149044 0.000694663
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.231015 0.0773453 0.53928
Brugia malayi Dopamine receptor protein 2 0.12315 0.0404724 0.282228
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Trypanosoma brucei monoglyceride lipase, putative 0.0707933 0.0225747 0.156142
Mycobacterium ulcerans 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD 0.354047 0.119403 1
Brugia malayi Latrophilin receptor protein 2 0.0171889 0.00425039 0.0291562
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0103383 0.00190857 0.00216734
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.292414 0.0983339 0.556589
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.164161
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0104602 0.00195022 0.0111223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Brugia malayi putative neuropeptide receptor 0.12315 0.0404724 0.282228
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0266621 0.00748875 0.0517816
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0103383 0.00190857 0.0108029
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0306758 0.00886077 0.061549
Schistosoma mansoni biogenic amine (5HT) receptor 0.258517 0.0867465 0.491003
Echinococcus multilocularis glutamate receptor NMDA 0.00785192 0.00105862 0.000981409
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus aminopeptidase N 0.142011 0.0469198 0.0468963
Loa Loa (eye worm) neuropeptide F receptor 0.12315 0.0404724 0.0465333
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0266621 0.00748875 0.0517816
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0068986 0.000732728 0.000655496
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0737154 0.0235735 0.0235495
Echinococcus granulosus protein kinase C gamma type 0.0169765 0.00417778 0.00415322
Loa Loa (eye worm) RGC/RGC protein kinase 0.00650175 0.000597069 0.000658524
Toxoplasma gondii flavodoxin domain-containing protein 0.00692806 0.000742802 0.00564061
Echinococcus multilocularis transient receptor potential cation channel 0.0068986 0.000732728 0.000655496
Trypanosoma brucei cytochrome P450, putative 0.00917279 0.00151015 0.00878963
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0068986 0.000732728 0.00414739
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Echinococcus multilocularis AMP deaminase 2 0.231015 0.0773453 0.077274
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0251146 0.00695975 0.0752229
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.536088 0.181632 0.181569
Echinococcus multilocularis carbonic anhydrase 0.0081147 0.00114844 0.00107124
Trypanosoma brucei carbonic anhydrase-like protein 0.0265031 0.00743438 0.0502315
Loa Loa (eye worm) follicle stimulating hormone receptor 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus somatostatin receptor 0.12315 0.0404724 0.0404488
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0113748 0.00226288 0.00223827
Loa Loa (eye worm) hypothetical protein 0.0113748 0.00226288 0.00257496
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Onchocerca volvulus 0.0251146 0.00695975 0.0844503
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.00869785 0.00134779 0.0090683
Loa Loa (eye worm) hypothetical protein 0.0251146 0.00695975 0.0079785
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0328793 0.00961403 0.00953748
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) hypothetical protein 0.00810491 0.0011451 0.00128901
Schistosoma mansoni carbonic anhydrase-related 0.0081147 0.00114844 0.00650042
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.00519717 0.000151107 0.000126444
Trichomonas vaginalis conserved hypothetical protein 0.0707933 0.0225747 0.849257
Schistosoma mansoni metabotropic glutamate receptor 0.00519113 0.000149044 0.000843619
Schistosoma mansoni neuropeptide F-like receptor 0.12315 0.0404724 0.229082
Giardia lamblia Kinase, CDC7 0.0194327 0.00501741 0.126659
Echinococcus multilocularis transient receptor potential cation channel 0.0068986 0.000732728 0.000655496
Onchocerca volvulus 0.12315 0.0404724 0.495663
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.26117
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.00702188 0.000774871 0.00487383
Trypanosoma cruzi heat shock protein, putative 0.0150307 0.00351261 0.0241903
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0068986 0.000732728 0.00335136
Schistosoma mansoni hypothetical protein 0.0081147 0.00114844 0.00650042
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0109774 0.00212704 0.00241869
Schistosoma mansoni histamine h1 receptor 0.12315 0.0404724 0.229082
Schistosoma mansoni growth hormone secretagogue receptor 0.12315 0.0404724 0.229082
Trypanosoma brucei monoglyceride lipase, putative 0.0707933 0.0225747 0.156142
Schistosoma mansoni neuropeptide receptor 0.12315 0.0404724 0.229082
Schistosoma mansoni neuropeptide F-like receptor 0.12315 0.0404724 0.229082
Leishmania major lanosterol 14-alpha-demethylase, putative 0.00659567 0.000629176 0.00404854
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Schistosoma mansoni neurotransmitter gated ion channel 0.0122987 0.00257871 0.014596
Trypanosoma cruzi monoglyceride lipase, putative 0.0707933 0.0225747 0.157345
Loa Loa (eye worm) hypothetical protein 0.00519113 0.000149044 0.000143091
Giardia lamblia NADPH oxidoreductase, putative 0.0117129 0.00237844 0.0355737
Echinococcus multilocularis roundabout 2 0.00509187 0.000115113 0.0000378325
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0266621 0.00748875 0.0517816
Brugia malayi Sodium:neurotransmitter symporter family protein 0.243387 0.0815745 0.569395
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Plasmodium falciparum plasmepsin I 0.0220095 0.00589829 0.0633427
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Loa Loa (eye worm) glutamate receptor 1 0.0177729 0.00445003 0.00509119
Echinococcus multilocularis shaker cognate 0.00702188 0.000774871 0.000697641
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0068986 0.000732728 0.00457939
Schistosoma mansoni diflavin oxidoreductase 0.00692806 0.000742802 0.00420441
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0113748 0.00226288 0.0154605
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Brugia malayi ERG2 and Sigma1 receptor like protein 0.146825 0.0485655 0.338772
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0158693 0.00379931 0.039247
Treponema pallidum nicotinate phosphoribosyltransferase 0.00705803 0.000787229 0.00605696
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Echinococcus multilocularis heat shock protein 90 0.0279476 0.00792816 0.00785149
Schistosoma mansoni glutamate receptor kainate 0.0177729 0.00445003 0.0251881
Giardia lamblia Grp94/Hsp90 0.0279476 0.00792816 0.227125
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0113748 0.00226288 0.0226538
Brugia malayi FAD binding domain containing protein 0.0102515 0.00187889 0.0125872
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0140552
Plasmodium falciparum amino acid transporter, putative 0.0737154 0.0235735 0.26117
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0630373 0.0199233 0.748193
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0251146 0.00695975 0.254049
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.00510155 0.000118421 0.0000411414
Loa Loa (eye worm) plexin A 0.0121218 0.00251824 0.00286874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Loa Loa (eye worm) hypothetical protein 0.00842528 0.00125461 0.001415
Plasmodium vivax aspartyl protease, putative 0.00868516 0.00134345 0.0117429
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0220399
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.12315 0.0404724 0.0465333
Mycobacterium ulcerans amidase 0.0104602 0.00195022 0.0111223
Plasmodium vivax adenosine deaminase, putative 0.082362 0.0265293 0.293809
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0068986 0.000732728 0.00414739
Schistosoma mansoni ryanodine receptor related 0.0068986 0.000732728 0.00414739
Loa Loa (eye worm) hypothetical protein 0.00498121 0.000077283 0.0000605335
Plasmodium vivax DNA gyrase subunit B, putative 0.00869785 0.00134779 0.0117915
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) ACC-1 protein 0.0266621 0.00748875 0.00858709
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.00549711 0.000253641 0.00142531
Schistosoma mansoni amine GPCR 0.38287 0.129256 0.731614
Brugia malayi Amidase family protein 0.0104602 0.00195022 0.0130856
Echinococcus multilocularis transfer RNA-Lys 0.00821922 0.00118417 0.00110698
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0737154 0.0235735 0.0235495
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.00641896 0.000568767 0.000544115
Plasmodium vivax plasmepsin V, putative 0.00868516 0.00134345 0.0117429
Giardia lamblia Heat shock protein HSP 90-alpha 0.0366454 0.0109015 0.32975
Loa Loa (eye worm) melatonin receptor type 1A 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.0171889 0.00425039 0.00486151
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.231015 0.0773453 0.539937
Giardia lamblia Nitric oxide synthase, inducible 0.0145592 0.00335143 0.0691569
Brugia malayi dihydrofolate reductase family protein 0.186928 0.0622745 0.434552
Echinococcus multilocularis neuropeptide FF receptor 2 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) cytochrome P450 0.00659567 0.000629176 0.000695461
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0707933 0.0225747 0.849257
Schistosoma mansoni carbonic anhydrase-related 0.0081147 0.00114844 0.00650042
Brugia malayi Serotonin receptor 0.12315 0.0404724 0.282228
Loa Loa (eye worm) hypothetical protein 0.046318 0.014208 0.0163172
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.022964 0.00622458 0.00614777
Echinococcus granulosus hyperpolarization activated cyclic 0.0103383 0.00190857 0.00188395
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.124604 0.0409693 0.2857
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Trypanosoma cruzi spermidine synthase, putative 0.0371552 0.0110757 0.0770211
Trypanosoma brucei heat shock protein 90, putative 0.0366454 0.0109015 0.0744848
Schistosoma mansoni biogenic amine (dopamine) receptor 0.12315 0.0404724 0.229082
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.12315 0.0404724 0.282228
Onchocerca volvulus 0.0122987 0.00257871 0.0306934
Brugia malayi Peptidase family M1 containing protein 0.142011 0.0469198 0.327274
Loa Loa (eye worm) hypothetical protein 0.0737154 0.0235735 0.0270919
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.00820552 0.00117949 0.00110229
Schistosoma mansoni fatty-acid amide hydrolase 0.0104602 0.00195022 0.0110386
Schistosoma mansoni sodium-dependent amino acid transporter 0.0737154 0.0235735 0.133431
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0328793 0.00961403 0.0544173
Brugia malayi Protein kinase domain containing protein 0.0836518 0.0269703 0.187893
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.011584 0.00233439 0.0161933
Loa Loa (eye worm) hypothetical protein 0.0183358 0.00464245 0.00531255
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0158693 0.00379931 0.026193
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Echinococcus multilocularis voltage dependent calcium channel 0.0964222 0.0313357 0.0312609
Brugia malayi ion channel NompC 0.0068986 0.000732728 0.00457939
Plasmodium vivax phosphodiesterase gamma, putative 0.0113748 0.00226288 0.0220399
Loa Loa (eye worm) hypothetical protein 0.01125 0.00222023 0.0025259
Brugia malayi metabotropic glutamate receptor type 2 0.0192155 0.00494317 0.0339965
Trypanosoma cruzi membrane transporter protein, putative 0.00565359 0.000307131 0.00179895
Echinococcus granulosus allatostatin A receptor 0.12315 0.0404724 0.0404488
Plasmodium falciparum esterase, putative 0.0707933 0.0225747 0.24999
Loa Loa (eye worm) hypothetical protein 0.0407076 0.0122901 0.0141108
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0117997 0.00240813 0.0136305
Echinococcus granulosus hypothetical protein 0.292908 0.0985031 0.0984809
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.00869785 0.00134779 0.00127061
Loa Loa (eye worm) PDE1B protein 0.0113748 0.00226288 0.00257496
Echinococcus granulosus neuropeptide Y receptor 0.12315 0.0404724 0.0404488
Schistosoma mansoni protein kinase 0.00650175 0.000597069 0.00337953
Toxoplasma gondii transporter, cation channel family protein 0.0068986 0.000732728 0.00552786
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.164161
Schistosoma mansoni acetylcholine receptor-related 0.0122987 0.00257871 0.014596
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0266621 0.00748875 0.00741204
Echinococcus multilocularis glutamate receptor subunit protein glur 0.00657698 0.000622786 0.000545545
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) hypothetical protein 0.00869785 0.00134779 0.00152219
Onchocerca volvulus 0.12315 0.0404724 0.495663
Entamoeba histolytica protein kinase, putative 0.00641896 0.000568767 0.00543709
Echinococcus granulosus fmrfamide receptor 0.12315 0.0404724 0.0404488
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0113748 0.00226288 0.00223827
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Echinococcus multilocularis nmda type glutamate receptor 0.0144289 0.00330691 0.00322987
Schistosoma mansoni amine GPCR 0.12315 0.0404724 0.229082
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.012826 0.00275897 0.00268189
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0251146 0.00695975 0.00693525
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0934516 0.0303202 0.0302453
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.12315 0.0404724 0.0403983
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0328793 0.00961403 0.0544173
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0113748 0.00226288 0.00218576
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) voltage-gated potassium channel 0.00702188 0.000774871 0.000863077
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0104602 0.00195022 0.0191544
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0661519 0.020988 0.118796
Schistosoma mansoni voltage-gated potassium channel 0.0093863 0.00158313 0.00896083
Leishmania major DNA topoisomerase ii 0.00869785 0.00134779 0.0090683
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0113748 0.00226288 0.0154605
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.00869785 0.00134779 0.0090683
Echinococcus granulosus heat shock protein 0.0366454 0.0109015 0.0108771
Toxoplasma gondii aminopeptidase n, putative 0.0251146 0.00695975 0.0752229
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.00869785 0.00134779 0.0090683
Treponema pallidum sodium- and chloride- dependent transporter 0.243387 0.0815745 1
Mycobacterium ulcerans two component regulator - sensor kinase 0.00869785 0.00134779 0.00605028
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0068986 0.000732728 0.00414739
Brugia malayi metabotropic GABA-B receptor subtype 2 0.00519113 0.000149044 0.000501372
Plasmodium falciparum plasmepsin VI 0.0220095 0.00589829 0.0633427
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0707933 0.0225747 0.849257
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.00869785 0.00134779 0.00605028
Trypanosoma cruzi adenosine kinase, putative 0.00810491 0.0011451 0.00765244
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus neuropeptide receptor 0.12315 0.0404724 0.0404488
Brugia malayi RE15519p 0.12315 0.0404724 0.282228
Brugia malayi thymidylate synthase 0.156048 0.0517183 0.360799
Onchocerca volvulus Putative nachr subunit 0.0407076 0.0122901 0.149855
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Trichomonas vaginalis receptor histidine kinase, putative 0.00869785 0.00134779 0.0401331
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0707933 0.0225747 0.849257
Onchocerca volvulus 0.12315 0.0404724 0.495663
Trichomonas vaginalis sulfite reductase, putative 0.0158693 0.00379931 0.13358
Plasmodium vivax spermidine synthase, putative 0.0371552 0.0110757 0.120738
Mycobacterium ulcerans peptide amidase, GatA 0.0104602 0.00195022 0.0111223
Schistosoma mansoni tyrosine kinase 0.0308721 0.00892788 0.0505336
Echinococcus multilocularis glutamate receptor 2 0.022964 0.00622458 0.00614777
Loa Loa (eye worm) calcium channel 0.0964222 0.0313357 0.036022
Mycobacterium ulcerans lysophospholipase 0.0707933 0.0225747 0.184767
Echinococcus multilocularis potassium voltage gated channel protein 0.00702188 0.000774871 0.000697641
Brugia malayi Cation transporter family protein 0.0266621 0.00748875 0.0517816
Schistosoma mansoni vesicular amine transporter 0.0115114 0.00230958 0.0130727
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.302371 0.101738 0.101716
Entamoeba histolytica type A flavoprotein, putative 0.00561787 0.000294922 0.0018897
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.00869785 0.00134779 0.00605028
Plasmodium vivax endoplasmin, putative 0.0366454 0.0109015 0.118787
Echinococcus multilocularis neuropeptides capa receptor 0.12315 0.0404724 0.0403983
Entamoeba histolytica protein kinase, putative 0.00641896 0.000568767 0.00543709
Loa Loa (eye worm) hypothetical protein 0.0372574 0.0111107 0.0127539
Onchocerca volvulus 0.12315 0.0404724 0.495663
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0117997 0.00240813 0.0150713
Echinococcus granulosus fatty acid amide hydrolase 1 0.0823619 0.0265293 0.0265053
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0820769 0.0264319 0.0263566
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Echinococcus granulosus glycine receptor subunit beta 0.0328793 0.00961403 0.0095896
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Echinococcus multilocularis biogenic amine (5HT) receptor 0.258517 0.0867465 0.0866759
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227177
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0122987 0.00257871 0.00250162
Schistosoma mansoni serine/threonine protein kinase 0.00519717 0.000151107 0.000855297
Brugia malayi heat shock protein 90 0.0366454 0.0109015 0.0756251
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Loa Loa (eye worm) hypothetical protein 0.0964222 0.0313357 0.036022
Schistosoma mansoni hypothetical protein 0.0298168 0.00856715 0.0484918
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227691
Trichomonas vaginalis CMGC family protein kinase 0.0194327 0.00501741 0.180011
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0714326 0.0227932 0.157671
Brugia malayi amidase 0.0823619 0.0265293 0.184812
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0068986 0.000732728 0.00457939
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0113748 0.00226288 0.0140552
Schistosoma mansoni serine/threonine protein kinase 0.00545379 0.000238831 0.00135183
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0117997 0.00240813 0.00233103
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0142323 0.00323968 0.0183373
Onchocerca volvulus 0.0266621 0.00748875 0.0909414
Echinococcus granulosus tm gpcr rhodopsin 0.536088 0.181632 0.181612
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.12315 0.0404724 0.0403983
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.00869785 0.00134779 0.0124118
Echinococcus granulosus serine:threonine protein kinase N2 0.0132641 0.00290873 0.00288413
Plasmodium vivax adenosine/AMP deaminase, putative 0.231015 0.0773453 0.862917
Toxoplasma gondii hypothetical protein 0.0117997 0.00240813 0.0242795
Schistosoma mansoni biogenic amine (dopamine) receptor 0.12315 0.0404724 0.229082
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0820769 0.0264319 0.0264079
Brugia malayi TATA binding protein associated factor 0.0251146 0.00695975 0.0480856
Mycobacterium ulcerans DNA gyrase subunit B 0.00869785 0.00134779 0.00605028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Schistosoma mansoni hypothetical protein 0.12315 0.0404724 0.229082
Echinococcus granulosus endoplasmin 0.0279476 0.00792816 0.00790369
Leishmania major AMP deaminase, putative 0.231015 0.0773453 0.539937
Echinococcus multilocularis hyperpolarization activated cyclic 0.0103383 0.00190857 0.00183142
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0220095 0.00589829 0.0333855
Trypanosoma brucei Heat shock protein 83, putative 0.0366454 0.0109015 0.0744848
Entamoeba histolytica hypothetical protein 0.0143634 0.00328453 0.0406171
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0113748 0.00226288 0.0154605
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0377729 0.0112869 0.0112105
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.00869785 0.00134779 0.00605028
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.12315 0.0404724 0.282228
Echinococcus granulosus voltage gated potassium channel 0.00702188 0.000774871 0.000750223
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0407076 0.0122901 0.0122137
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Schistosoma mansoni adenosine deaminase 0.082362 0.0265293 0.150161
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.00869785 0.00134779 0.00879553
Brugia malayi protein kinase C3,putative 0.00519717 0.000151107 0.000515787
Schistosoma mansoni biogenic amine receptor 0.12315 0.0404724 0.229082
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.022964 0.00622458 0.00614777
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0266621 0.00748875 0.0423878
Loa Loa (eye worm) AMP deaminase 0.231015 0.0773453 0.088954
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0630373 0.0199233 0.748193
Echinococcus multilocularis serine:threonine protein kinase 38 0.00641896 0.000568767 0.000491522
Giardia lamblia Hypothetical protein 0.0113748 0.00226288 0.0315848
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0298168 0.00856715 0.0484918
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Echinococcus multilocularis tachykinin peptides receptor 99D 0.12315 0.0404724 0.0403983
Echinococcus multilocularis sodium and chloride dependent glycine 0.0737154 0.0235735 0.0234981
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Onchocerca volvulus DNA topoisomerase 2 homolog 0.00869785 0.00134779 0.0155896
Onchocerca volvulus 0.00842528 0.00125461 0.0144463
Brugia malayi Eukaryotic aspartyl protease family protein 0.00868516 0.00134345 0.00884632
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.022964 0.00622458 0.00614777
Brugia malayi hypothetical protein 0.0122987 0.00257871 0.0174767
Trypanosoma cruzi heat shock protein 90, putative 0.0279476 0.00792816 0.0550344
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0328793 0.00961403 0.00953748
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.132765 0.0437592 0.247686
Plasmodium falciparum heat shock protein 90, putative 0.0150307 0.00351261 0.0366413
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0171889 0.00425039 0.00422583
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0103383 0.00190857 0.00183142
Echinococcus granulosus GPCR family 3 C terminal 0.00578628 0.000352491 0.000327833
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.186928 0.0622745 0.519015
Loa Loa (eye worm) hypothetical protein 0.00645142 0.000579865 0.000638731
Schistosoma mansoni transient receptor potential channel 0.0068986 0.000732728 0.00414739
Onchocerca volvulus 0.243387 0.0815745 1
Loa Loa (eye worm) hypothetical protein 0.0251146 0.00695975 0.0079785
Onchocerca volvulus 0.0266621 0.00748875 0.0909414
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0298168 0.00856715 0.00849053
Plasmodium vivax heat shock protein 86, putative 0.0366454 0.0109015 0.118787
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.00869785 0.00134779 0.0401331
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.00641896 0.000568767 0.000625964
Loa Loa (eye worm) heat shock protein 75 0.0150307 0.00351261 0.00401272
Echinococcus granulosus neuropeptide FF receptor 2 0.12315 0.0404724 0.0404488
Onchocerca volvulus 0.12315 0.0404724 0.495663
Echinococcus granulosus potassium voltage gated channel protein 0.0112938 0.0022352 0.00221059
Trypanosoma brucei membrane transporter protein, putative 0.00565359 0.000307131 0.000374174
Trypanosoma cruzi aminopeptidase, putative 0.0714326 0.0227932 0.158872
Schistosoma mansoni heat shock protein 0.0366454 0.0109015 0.0617044
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Echinococcus multilocularis carbonic anhydrase II 0.0265031 0.00743438 0.00735767
Mycobacterium ulcerans putative regulatory protein 0.00821922 0.00118417 0.00467273
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0174667 0.00434535 0.0300073
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0113748 0.00226288 0.00218576
Echinococcus multilocularis neuropeptide s receptor 0.443883 0.150113 0.150047
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0630373 0.0199233 0.748193
Echinococcus granulosus g protein coupled receptor 0.12315 0.0404724 0.0404488
Brugia malayi Protein kinase c protein 2 0.0157547 0.00376012 0.0257309
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Schistosoma mansoni hypothetical protein 0.0068986 0.000732728 0.00414739
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0113748 0.00226288 0.00218576
Echinococcus multilocularis mitogen activated protein kinase 14 0.423681 0.143207 0.14314
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.12315 0.0404724 0.229082
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00703584
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.00657698 0.000622786 0.000598135
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0068986 0.000732728 0.00457939
Echinococcus granulosus twitchin 0.0067682 0.000688152 0.000663502
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0742363 0.0237516 0.165567
Brugia malayi DNA topoisomerase II, alpha isozyme 0.00869785 0.00134779 0.00887663
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.423681 0.143207 1
Echinococcus granulosus neuropeptides capa receptor 0.12315 0.0404724 0.0404488
Echinococcus granulosus potassium large conductance calcium activated 0.0068986 0.000732728 0.000708079
Brugia malayi Protein kinase domain containing protein 0.00641896 0.000568767 0.00343385
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0104602 0.00195022 0.00187308
Trypanosoma brucei DNA topoisomerase ii 0.00869785 0.00134779 0.0076539
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0604488 0.0190385 0.131406
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0158693 0.00379931 0.00377474
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Brugia malayi cation channel family protein 0.0068986 0.000732728 0.00457939
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Chlamydia trachomatis sulfite reductase 0.0102515 0.00187889 0.00871699
Echinococcus granulosus cGMP dependent protein kinase 1 0.00545379 0.000238831 0.000214171
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0068986 0.000732728 0.00414739
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0291589 0.00834224 0.00831778
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0964222 0.0313357 0.177366
Loa Loa (eye worm) sema domain-containing protein 0.00498121 0.000077283 0.0000605335
Schistosoma mansoni fatty-acid amide hydrolase 0.0823619 0.0265293 0.150161
Trichomonas vaginalis conserved hypothetical protein 0.0707933 0.0225747 0.849257
Echinococcus granulosus mitogen activated protein kinase 11 0.423681 0.143207 0.143185
Echinococcus granulosus DNA topoisomerase 2 alpha 0.00869785 0.00134779 0.00132316
Echinococcus multilocularis short transient receptor potential channel 6 0.0068986 0.000732728 0.000655496
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122987 0.00257871 0.0174767
Mycobacterium ulcerans leucyl aminopeptidase 0.0277117 0.00784754 0.0607741
Toxoplasma gondii aspartyl protease ASP1 0.0220095 0.00589829 0.0633427
Echinococcus multilocularis alpha 1A adrenergic receptor 0.12315 0.0404724 0.0403983
Schistosoma mansoni multidrug resistance protein 0.00565359 0.000307131 0.00173842
Echinococcus granulosus plexin a4 0.0121218 0.00251824 0.00249363
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227177
Loa Loa (eye worm) hypothetical protein 0.0178995 0.0044933 0.00514097
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.00561787 0.000294922 0.00171367
Echinococcus multilocularis orexin receptor type 2 0.12315 0.0404724 0.0403983
Trypanosoma brucei DNA topoisomerase II beta, putative 0.00869785 0.00134779 0.0076539
Plasmodium falciparum plasmepsin VIII, putative 0.00868516 0.00134345 0.0123633
Plasmodium falciparum plasmepsin X 0.00868516 0.00134345 0.0123633
Onchocerca volvulus 0.0122987 0.00257871 0.0306934
Loa Loa (eye worm) ion channel NompC 0.0068986 0.000732728 0.000814594
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.12315 0.0404724 0.229082
Schistosoma mansoni voltage-gated ion channel 0.0068986 0.000732728 0.00414739
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0068986 0.000732728 0.000655496
Loa Loa (eye worm) hypothetical protein 0.00997267 0.00178358 0.00202355
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.266822 0.0895856 1
Leishmania major adenine aminohydrolase 0.082362 0.0265293 0.18497
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.245601 0.0823313 1
Echinococcus granulosus potassium voltage gated channel protein 0.00820552 0.00117949 0.00115485
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Onchocerca volvulus 0.0306758 0.00886077 0.107777
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.00869785 0.00134779 0.00127061
Schistosoma mansoni neuropeptide f receptor 76f 0.12315 0.0404724 0.229082
Toxoplasma gondii aspartyl protease 0.00868516 0.00134345 0.0123633
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0174667 0.00434535 0.0286228
Echinococcus granulosus CDC7 cell division cycle 7 0.0194327 0.00501741 0.00499286
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Loa Loa (eye worm) voltage-gated potassium channel 0.00733366 0.000881451 0.000985693
Plasmodium vivax aspartyl protease, putative 0.00868516 0.00134345 0.0117429
Giardia lamblia Hypothetical protein 0.0145592 0.00335143 0.0691569
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.231015 0.0773453 0.539937
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Brugia malayi Melatonin receptor type 1A 0.12315 0.0404724 0.282228
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.00702188 0.000774871 0.00487383
Toxoplasma gondii kinase, pfkB family protein 0.00810491 0.0011451 0.0101433
Echinococcus granulosus GPCR family 2 0.0171889 0.00425039 0.00422583
Echinococcus granulosus cGMP dependent protein kinase 0.00545379 0.000238831 0.000214171
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.022964 0.00622458 0.00620007
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0210902 0.00558402 0.00639579
Loa Loa (eye worm) hypothetical protein 0.00842528 0.00125461 0.001415
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.12315 0.0404724 0.229082
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Trypanosoma cruzi Emopamil binding protein, putative 0.0306758 0.00886077 0.061549
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0143634 0.00328453 0.022408
Trypanosoma cruzi hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Brugia malayi PAS domain containing protein 0.0111054 0.00217078 0.0146266
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.00869785 0.00134779 0.00605028
Trypanosoma cruzi DNA topoisomerase II, putative 0.00869785 0.00134779 0.0090683
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0113748 0.00226288 0.0226538
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Loa Loa (eye worm) hypothetical protein 0.0113748 0.00226288 0.00257496
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.26117
Schistosoma mansoni plexin 0.00997267 0.00178358 0.0100954
Trypanosoma cruzi AMP deaminase, putative 0.231015 0.0773453 0.539937
Plasmodium falciparum plasmepsin VII 0.00868516 0.00134345 0.0123633
Echinococcus multilocularis leucine aminopeptidase protein 0.0277117 0.00784754 0.00777085
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Plasmodium falciparum lysophospholipase, putative 0.0707933 0.0225747 0.24999
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.00869785 0.00134779 0.0401331
Trypanosoma cruzi hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0158693 0.00379931 0.00377474
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.292414 0.0983339 0.0983116
Leishmania major adenosine kinase, putative 0.00810491 0.0011451 0.00765244
Schistosoma mansoni cytochrome P450 0.00659567 0.000629176 0.00356126
Trichomonas vaginalis conserved hypothetical protein 0.00871073 0.00135219 0.0403009
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.00702188 0.000774871 0.000750223
Trypanosoma brucei developmentally regulated phosphoprotein 0.00869785 0.00134779 0.0076539
Brugia malayi C1-like domain containing protein 0.00519717 0.000151107 0.000515787
Onchocerca volvulus 0.0143634 0.00328453 0.0393541
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0104602 0.00195022 0.0111223
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.00650175 0.000597069 0.00637796
Schistosoma mansoni carbonic anhydrase 0.0081147 0.00114844 0.00650042
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0737154 0.0235735 0.133431
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0266621 0.00748875 0.0423878
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.423681 0.143207 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.26117
Leishmania major hypothetical protein, conserved 0.0306758 0.00886077 0.061549
Schistosoma mansoni cytochrome P450 reductase 0.0158693 0.00379931 0.0215049
Echinococcus granulosus transient receptor potential gamma protein 0.0068986 0.000732728 0.000708079
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0964222 0.0313357 0.218393
Echinococcus multilocularis expressed conserved protein 0.00545379 0.000238831 0.000161561
Mycobacterium ulcerans adenosine deaminase 0.082362 0.0265293 0.218063
Schistosoma mansoni 60S ribosomal protein L21 0.0093863 0.00158313 0.00896083
Loa Loa (eye worm) ryanodine receptor 0.0068986 0.000732728 0.000814594
Echinococcus granulosus TRP transient receptor potential channel 0.0068986 0.000732728 0.000708079
Loa Loa (eye worm) hypothetical protein 0.0251146 0.00695975 0.0079785
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227177
Echinococcus multilocularis conserved hypothetical protein 0.00820552 0.00117949 0.00110229
Schistosoma mansoni sodium/chloride dependent transporter 0.0757295 0.0242621 0.137328
Echinococcus multilocularis two pore calcium channel protein 1 0.0068986 0.000732728 0.000655496
Echinococcus granulosus two pore calcium channel protein 2 0.0068986 0.000732728 0.000708079
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0630373 0.0199233 0.0228925
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Brugia malayi hypothetical protein 0.00571103 0.000326768 0.00174307
Loa Loa (eye worm) hypothetical protein 0.116896 0.0383346 0.0440739
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus multilocularis metabotropic glutamate receptor 2 0.00519113 0.000149044 0.0000717666
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0068986 0.000732728 0.000655496
Loa Loa (eye worm) hypothetical protein 0.0081147 0.00114844 0.00129286
Trichomonas vaginalis adenosine deaminase, putative 0.082362 0.0265293 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.292414 0.0983339 0.0982642
Echinococcus multilocularis transient receptor potential cation channel 0.0068986 0.000732728 0.000655496
Echinococcus granulosus adenosine deaminase 0.082362 0.0265293 0.0265053
Leishmania major mitochondrial DNA topoisomerase II 0.00869785 0.00134779 0.0090683
Mycobacterium ulcerans hypothetical protein 0.0707933 0.0225747 0.184767
Schistosoma mansoni hypothetical protein 0.00499146 0.0000807884 0.000457279
Brugia malayi sulfakinin receptor protein 0.12315 0.0404724 0.282228
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0251146 0.00695975 0.0482697
Echinococcus multilocularis fmrfamide receptor 0.12315 0.0404724 0.0403983
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0251146 0.00695975 0.074642
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0220399
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0737154 0.0235735 0.364795
Loa Loa (eye worm) hypothetical protein 0.0257192 0.0071664 0.00821625
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0113748 0.00226288 0.0152701
Leishmania major hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0104602 0.00195022 0.0915492
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Brugia malayi hypothetical protein 0.00842528 0.00125461 0.00822564
Echinococcus multilocularis transient receptor potential gamma protein 0.0068986 0.000732728 0.000655496
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Schistosoma mansoni glutamate receptor AMPA 0.0177729 0.00445003 0.0251881
Trypanosoma cruzi AMP deaminase, putative 0.231015 0.0773453 0.539937
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0266621 0.00748875 0.0423878
Brugia malayi Dopamine receptor 0.12315 0.0404724 0.282228
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0158693 0.00379931 0.026193
Echinococcus granulosus protein kinase c epsilon type 0.0210902 0.00558402 0.0055595
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0068986 0.000732728 0.00457939
Leishmania major hypothetical protein, conserved 0.00869785 0.00134779 0.0090683
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0117997 0.00240813 0.0242795
Loa Loa (eye worm) hypothetical protein 0.292414 0.0983339 0.1131
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0122987 0.00257871 0.0174767
Trypanosoma cruzi AMP deaminase, putative 0.231015 0.0773453 0.539937
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0266621 0.00748875 0.0517816
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0220095 0.00589829 0.213589
Brugia malayi neuropeptide F receptor 0.12315 0.0404724 0.282228
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0266621 0.00748875 0.00858709
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0104602 0.00195022 0.0185383
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0117997 0.00240813 0.0236666
Schistosoma mansoni adenoreceptor 0.12315 0.0404724 0.229082
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0266621 0.00748875 0.00746427
Trichomonas vaginalis heat shock protein, putative 0.0279476 0.00792816 0.290963
Schistosoma mansoni voltage-gated potassium channel 0.012826 0.00275897 0.0156163
Echinococcus multilocularis neuropeptide Y receptor 0.12315 0.0404724 0.0403983
Schistosoma mansoni dihydrofolate reductase 0.186928 0.0622745 0.352486
Echinococcus multilocularis dro:myosuppressin receptor 0.12315 0.0404724 0.0403983
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Echinococcus granulosus tm gpcr rhodopsin 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) hypothetical protein 0.00842528 0.00125461 0.001415
Toxoplasma gondii hypothetical protein 0.0169106 0.00415525 0.043834
Echinococcus granulosus thyrotropin releasing hormone receptor 0.12315 0.0404724 0.0404488
Echinococcus granulosus G protein coupled receptor 139 0.12315 0.0404724 0.0404488
Schistosoma mansoni hypothetical protein 0.12315 0.0404724 0.229082
Echinococcus granulosus transient receptor potential cation channel 0.0068986 0.000732728 0.000708079
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0279476 0.00792816 0.00790369
Loa Loa (eye worm) G-protein coupled receptor 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.302371 0.101738 0.101668
Trypanosoma brucei heat shock protein 84, putative 0.0150307 0.00351261 0.0227975
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0266621 0.00748875 0.0517816
Brugia malayi olfactory channel protein osm-9 0.0068986 0.000732728 0.00457939
Echinococcus granulosus cytochrome P450 2K1 0.00659567 0.000629176 0.000604525
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Loa Loa (eye worm) hypothetical protein 0.00498121 0.000077283 0.0000605335
Echinococcus granulosus semaphorin 1A 0.00498121 0.000077283 0.0000526183
Brugia malayi Carboxylesterase family protein 0.0178995 0.0044933 0.0308533
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.00641896 0.000568767 0.000625964
Echinococcus multilocularis calcium activated potassium channel 0.00891268 0.00142123 0.00134405
Toxoplasma gondii cytochrome p450 superfamily protein 0.00659567 0.000629176 0.00436887
Trichomonas vaginalis sensor histidine kinase, putative 0.00869785 0.00134779 0.0401331
Entamoeba histolytica type A flavoprotein, putative 0.00561787 0.000294922 0.0018897
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.00578628 0.000352491 0.00192279
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.00641896 0.000568767 0.000491522
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0714326 0.0227932 0.0227691
Loa Loa (eye worm) RGC/RGC protein kinase 0.00650175 0.000597069 0.000658524
Trypanosoma brucei Aminopeptidase M1, putative 0.0714326 0.0227932 0.157671
Loa Loa (eye worm) hypothetical protein 0.00820552 0.00117949 0.00132857
Schistosoma mansoni biogenic amine receptor 0.12315 0.0404724 0.229082
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0081147 0.00114844 0.00748386
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.00869785 0.00134779 0.00605028
Echinococcus multilocularis carbonic anhydrase 0.0081147 0.00114844 0.00107124
Loa Loa (eye worm) hypothetical protein 0.00498121 0.000077283 0.0000605335
Loa Loa (eye worm) AGC/AKT protein kinase 0.00641896 0.000568767 0.000625964
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0068986 0.000732728 0.00414739
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0122987 0.00257871 0.00293832
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Brugia malayi flavodoxin family protein 0.00561787 0.000294922 0.00152057
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0103383 0.00190857 0.00188395
Onchocerca volvulus 0.007359 0.000890113 0.00997372
Echinococcus granulosus metabotropic glutamate receptor 2 0.00519113 0.000149044 0.000124381
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0113748 0.00226288 0.00223827
Plasmodium vivax hypothetical protein, conserved 0.0737154 0.0235735 0.260706
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0192155 0.00494317 0.00486627
Echinococcus multilocularis two pore calcium channel protein 2 0.0068986 0.000732728 0.000655496
Echinococcus granulosus g-protein coupled receptor 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.00641896 0.000568767 0.000625964
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0117129 0.00237844 0.0794195
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0266621 0.00748875 0.0517816
Plasmodium vivax amine transporter, putative 0.0737154 0.0235735 0.260706
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0707933 0.0225747 0.849257
Loa Loa (eye worm) hypothetical protein 0.00498121 0.000077283 0.0000605335
Schistosoma mansoni cell adhesion molecule 0.00482729 0.000024666 0.000139614
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Echinococcus granulosus semaphorin 5B 0.00498121 0.000077283 0.0000526183
Trypanosoma cruzi heat shock protein 90, putative 0.0366454 0.0109015 0.0758039
Onchocerca volvulus 0.015368 0.00362793 0.0435677
Trichomonas vaginalis conserved hypothetical protein 0.0742363 0.0237516 0.89412
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0104602 0.00195022 0.0118681
Leishmania major sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00703584
Loa Loa (eye worm) hypothetical protein 0.00702188 0.000774871 0.000863077
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.00519717 0.000151107 0.00007383
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0265031 0.00743438 0.0420801
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Trypanosoma cruzi hypothetical protein, conserved 0.0117997 0.00240813 0.0164751
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Schistosoma mansoni sodium/chloride dependent transporter 0.243387 0.0815745 0.461728
Brugia malayi Peptidase family M1 containing protein 0.0714326 0.0227932 0.158709
Schistosoma mansoni opsin-like receptor 0.12315 0.0404724 0.229082
Plasmodium vivax DNA topoisomerase II, putative 0.00869785 0.00134779 0.0117915
Echinococcus granulosus receptor type guanylyl cyclase 0.00650175 0.000597069 0.000572417
Brugia malayi Probable DNA topoisomerase II 0.00869785 0.00134779 0.00887663
Brugia malayi adenosine monophosphate deaminase 0.231015 0.0773453 0.539848
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0266621 0.00748875 0.00858709
Loa Loa (eye worm) solute carrier family 6 member 4 0.243387 0.0815745 0.0938194
Brugia malayi gonadotropin-releasing hormone receptor 2 0.12315 0.0404724 0.282228
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0103383 0.00190857 0.0615087
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Echinococcus granulosus poly ADP ribose polymerase 1 0.00884061 0.00139659 0.00137196
Loa Loa (eye worm) hypothetical protein 0.211663 0.0707298 0.081343
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0104602 0.00195022 0.016169
Schistosoma mansoni amine GPCR 0.12315 0.0404724 0.229082
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Brugia malayi hypothetical protein 0.0737154 0.0235735 0.164161
Trypanosoma brucei AMP deaminase, putative 0.231015 0.0773453 0.53928
Brugia malayi Serotonin/octopamine receptor family protein 7 0.132765 0.0437592 0.305192
Loa Loa (eye worm) glutamate receptor 0.0140244 0.00316862 0.00361698
Brugia malayi hypothetical protein 0.0251146 0.00695975 0.0480856
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.243387 0.0815745 0.461728
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0737154 0.0235735 0.133431
Brugia malayi hypothetical protein 0.0714326 0.0227932 0.158709
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0103383 0.00190857 0.00188395
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0113748 0.00226288 0.00223827
Plasmodium vivax aspartyl protease, putative 0.00868516 0.00134345 0.0117429
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.156048 0.0517183 0.430138
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0737154 0.0235735 0.0234981
Echinococcus multilocularis mitogen activated protein kinase 14 0.423681 0.143207 0.14314
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0627826 0.0198363 0.0198121
Brugia malayi hypothetical protein 0.00868516 0.00134345 0.00884632
Onchocerca volvulus 0.142011 0.0469198 0.574775
Schistosoma mansoni DNA topoisomerase II 0.00869785 0.00134779 0.00762876
Echinococcus multilocularis mitogen activated protein kinase 11 0.423681 0.143207 0.14314
Echinococcus granulosus tyrosine kinase 0.00650175 0.000597069 0.000572417
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.00869785 0.00134779 0.0401331
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0113748 0.00226288 0.0152701
Echinococcus multilocularis glutamate receptor 2 0.0163871 0.00397629 0.00389931
Loa Loa (eye worm) hypothetical protein 0.22972 0.0769026 0.0884446
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0604488 0.0190385 0.132644
Loa Loa (eye worm) hypothetical protein 0.0737154 0.0235735 0.0270919
Brugia malayi GnHR receptor homolog 0.12315 0.0404724 0.282228
Echinococcus multilocularis adenosine deaminase 0.082362 0.0265293 0.0264541
Schistosoma mansoni opsin-like receptor 0.12315 0.0404724 0.229082
Loa Loa (eye worm) amidase 0.0104602 0.00195022 0.00221526
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0158693 0.00379931 0.0248031
Echinococcus granulosus potassium voltage gated channel protein 0.00702188 0.000774871 0.000750223
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.00565359 0.000307131 0.000229865
Loa Loa (eye worm) hypothetical protein 0.132765 0.0437592 0.0503147
Echinococcus multilocularis neuropeptides capa receptor 0.12315 0.0404724 0.0403983
Schistosoma mansoni heat shock protein 0.0150307 0.00351261 0.0198821
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0142323 0.00323968 0.0220947
Toxoplasma gondii aminopeptidase N, putative 0.0251146 0.00695975 0.0752229
Brugia malayi neuropeptide F receptor 0.12315 0.0404724 0.282228
Chlamydia trachomatis dihydrofolate reductase 0.186928 0.0622745 1
Brugia malayi Cytochrome P450 family protein 0.00659567 0.000629176 0.0038559
Echinococcus multilocularis tyrosine kinase 0.00650175 0.000597069 0.000519826
Brugia malayi hypothetical protein 0.00842528 0.00125461 0.00822564
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.00869785 0.00134779 0.00605028
Trichomonas vaginalis receptor histidine kinase, putative 0.00869785 0.00134779 0.0401331
Onchocerca volvulus Adenosine deaminase homolog 0.082362 0.0265293 0.324576
Loa Loa (eye worm) FAD binding domain-containing protein 0.0158693 0.00379931 0.00434256
Brugia malayi Glutamate receptor 2 precursor 0.0177729 0.00445003 0.030551
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Trypanosoma cruzi adenosine kinase, putative 0.00810491 0.0011451 0.00765244
Schistosoma mansoni glutamate receptor AMPA 0.0177729 0.00445003 0.0251881
Schistosoma mansoni two-pore calcium channel 0.0068986 0.000732728 0.00414739
Entamoeba histolytica heat shock protein 90, putative 0.0366454 0.0109015 0.139287
Echinococcus multilocularis serine threonine protein kinase 0.0169765 0.00417778 0.00410082
Echinococcus granulosus potassium voltage gated channel subfamily H 0.012826 0.00275897 0.00273437
Plasmodium falciparum endoplasmin, putative 0.0237285 0.00648591 0.0699195
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Echinococcus multilocularis transient receptor potential cation channel 0.0068986 0.000732728 0.000655496
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus roundabout 2 0.00509187 0.000115113 0.0000904488
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0736072 0.0235366 0.280377
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0220399
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Schistosoma mansoni nAChR subunit 0.0122987 0.00257871 0.014596
Echinococcus granulosus protein kinase c iota type 0.00960204 0.00165688 0.00163226
Trypanosoma cruzi heat shock protein 85, putative 0.0279476 0.00792816 0.0550344
Trichomonas vaginalis endoplasmin, putative 0.0237285 0.00648591 0.235987
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.00702188 0.000774871 0.00487383
Brugia malayi Egg laying defective protein 4 0.00545379 0.000238831 0.00112869
Brugia malayi Receptor family ligand binding region containing protein 0.0109774 0.00212704 0.014321
Trypanosoma cruzi p450 reductase, putative 0.0158693 0.00379931 0.026193
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0174667 0.00434535 0.0300073
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0117997 0.00240813 0.0164751
Brugia malayi FAD binding domain containing protein 0.0158693 0.00379931 0.0260047
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0113748 0.00226288 0.00223827
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Schistosoma mansoni hypothetical protein 0.00657698 0.000622786 0.00352509
Echinococcus granulosus two pore calcium channel protein 1 0.0068986 0.000732728 0.000708079
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0251146 0.00695975 0.0482697
Trypanosoma brucei AMP deaminase, putative 0.231015 0.0773453 0.53928
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0068986 0.000732728 0.00414739
Echinococcus multilocularis acetylcholinesterase 0.0178995 0.0044933 0.00441636
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0143634 0.00328453 0.022408
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.00561787 0.000294922 0.000627782
Trypanosoma brucei membrane transporter protein, putative 0.00565359 0.000307131 0.000374174
Trypanosoma cruzi AMP deaminase, putative 0.231015 0.0773453 0.539937
Echinococcus granulosus sodium leak channel non selective protein 0.0068986 0.000732728 0.000708079
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.00641896 0.000568767 0.000625964
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.00869785 0.00134779 0.0124118
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0737154 0.0235735 0.0234981
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Loa Loa (eye worm) spermidine synthase 0.0371552 0.0110757 0.0127137
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0661519 0.020988 0.0241174
Echinococcus multilocularis glycine receptor subunit beta 0.0328793 0.00961403 0.00953748
Schistosoma mansoni serine/threonine protein kinase 0.00641896 0.000568767 0.00321934
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0158693 0.00379931 0.0248031
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0083288 0.00122163 0.001197
Loa Loa (eye worm) norepinephrine transporter 0.243387 0.0815745 0.0938194
Echinococcus granulosus g protein coupled receptor 0.12315 0.0404724 0.0404488
Schistosoma mansoni hypothetical protein 0.0298168 0.00856715 0.0484918
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0630373 0.0199233 0.220316
Loa Loa (eye worm) aspartyl protease 6 0.00868516 0.00134345 0.0015172
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.12315 0.0404724 0.0404488
Leishmania major developmentally regulated phosphoprotein-like protein 0.00869785 0.00134779 0.0090683
Loa Loa (eye worm) hypothetical protein 0.0934516 0.0303202 0.0348537
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0964222 0.0313357 0.0313118
Loa Loa (eye worm) acetylcholine receptor protein 0.0122987 0.00257871 0.00293832
Brugia malayi Dihydrofolate reductase 0.186928 0.0622745 0.434552
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.231015 0.0773453 0.539937
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0102515 0.00187889 0.0106349
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0328793 0.00961403 0.00953748
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0251146 0.00695975 0.0393936
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0387305 0.0116142 0.0115378
Mycobacterium leprae Probable two-component sensor kinase 0.00869785 0.00134779 0.00879553
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Loa Loa (eye worm) hypothetical protein 0.082362 0.0265293 0.0304924
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.292414 0.0983339 0.556589
Schistosoma mansoni hypothetical protein 0.00498121 0.000077283 0.000437437
Echinococcus multilocularis rhodopsin orphan GPCR 0.12315 0.0404724 0.0403983
Schistosoma mansoni voltage-gated potassium channel 0.0112938 0.0022352 0.0126517
Toxoplasma gondii Hsp90 domain-containing protein 0.0150307 0.00351261 0.0366413
Loa Loa (eye worm) LGC-31 protein 0.0266621 0.00748875 0.00858709
Echinococcus multilocularis RNA directed DNA polymerase 0.0103194 0.0019021 0.00182496
Echinococcus granulosus glycine receptor subunit alpha 1 0.0328793 0.00961403 0.0095896
Onchocerca volvulus 0.12315 0.0404724 0.495663
Entamoeba histolytica type A flavoprotein, putative 0.00561787 0.000294922 0.0018897
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.423681 0.143207 1
Brugia malayi G protein-coupled receptor F59B2.13 0.12315 0.0404724 0.282228
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0226639 0.00612199 0.222116
Echinococcus granulosus spermidine synthase 0.0371552 0.0110757 0.0110513
Echinococcus granulosus neuropeptide receptor A26 0.443883 0.150113 0.150092
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Echinococcus granulosus glutamate NMDA receptor subunit 0.0377729 0.0112869 0.0112625
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0117997 0.00240813 0.0162849
Loa Loa (eye worm) hypothetical protein 0.082362 0.0265293 0.0304924
Loa Loa (eye worm) hypothetical protein 0.00869785 0.00134779 0.00152219
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0142323 0.00323968 0.00316265
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0117997 0.00240813 0.0150713
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0387305 0.0116142 0.0115899
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Brugia malayi metabotropic GABA-B receptor subtype 2 0.00578628 0.000352491 0.00192279
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0298168 0.00856715 0.0085427
Loa Loa (eye worm) acetylcholinesterase 1 0.0178995 0.0044933 0.00514097
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.00657698 0.000622786 0.000545545
Echinococcus multilocularis serotonin transporter 0.243387 0.0815745 0.0815035
Schistosoma mansoni adenosine deaminase-related 0.082362 0.0265293 0.150161
Echinococcus granulosus transient receptor potential cation channel 0.0068986 0.000732728 0.000708079
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.012826 0.00275897 0.0187361
Loa Loa (eye worm) hypothetical protein 0.01125 0.00222023 0.0025259
Plasmodium falciparum lysophospholipase, putative 0.0707933 0.0225747 0.24999
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.046318 0.014208 0.0141318
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Loa Loa (eye worm) thymidylate synthase 0.156048 0.0517183 0.0594712
Echinococcus granulosus adenosine kinase 0.00810491 0.0011451 0.00112046
Echinococcus granulosus biogenic amine 5HT receptor 0.158537 0.0525691 0.0525457
Brugia malayi bHLH-PAS transcription factor 0.00821922 0.00118417 0.00773349
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0068986 0.000732728 0.00414739
Brugia malayi putative neuropeptide receptor NPR1 0.12315 0.0404724 0.282228
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0387305 0.0116142 0.0657389
Schistosoma mansoni serine/threonine protein kinase 0.00519717 0.000151107 0.000855297
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.00561787 0.000294922 0.000288768
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0151187 0.0035427 0.0439614
Loa Loa (eye worm) hypothetical protein 0.00509187 0.000115113 0.000104055
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0104602 0.00195022 0.0019256
Trichomonas vaginalis heat shock protein, putative 0.0279476 0.00792816 0.290963
Loa Loa (eye worm) FAD binding domain-containing protein 0.0102515 0.00187889 0.0021332
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0174667 0.00434535 0.0300073
Schistosoma mansoni myosin xvIII 0.12315 0.0404724 0.229082
Onchocerca volvulus Neuropeptide F receptor homolog 0.12315 0.0404724 0.495663
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0328793 0.00961403 0.0095896
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0113748 0.00226288 0.0140552
Onchocerca volvulus 0.0143634 0.00328453 0.0393541
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0183358 0.00464245 0.0318954
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0934516 0.0303202 0.171619
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.12315 0.0404724 0.495663
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00561854
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0104602 0.00195022 0.00988775
Echinococcus multilocularis CDC7 cell division cycle 7 0.0194327 0.00501741 0.0049405
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.00657698 0.000622786 0.000598135
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.00561787 0.000294922 0.00171367
Loa Loa (eye worm) hypothetical protein 0.00869785 0.00134779 0.00152219
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.00657698 0.000622786 0.000545545
Loa Loa (eye worm) RGC/RGC protein kinase 0.00650175 0.000597069 0.000658524
Loa Loa (eye worm) hypothetical protein 0.0328793 0.00961403 0.0110321
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.231015 0.0773453 0.539937
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0277117 0.00784754 0.0883497
Echinococcus multilocularis nmda type glutamate receptor 0.0130431 0.00283317 0.0027561
Schistosoma mansoni serine/threonine protein kinase 0.00641896 0.000568767 0.00321934
Brugia malayi hypothetical protein 0.0742363 0.0237516 0.165405
Leishmania major hypothetical protein, conserved 0.00565359 0.000307131 0.00179895
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0934516 0.0303202 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.0270919
Loa Loa (eye worm) CDC7 protein kinase 0.0194327 0.00501741 0.00574392
Brugia malayi putative amidase 0.0104602 0.00195022 0.0130856
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0279476 0.00792816 0.0550344
Schistosoma mansoni aminopeptidase A (M01 family) 0.0251146 0.00695975 0.0393936
Trypanosoma cruzi amidase, putative 0.0104602 0.00195022 0.0132765
Echinococcus granulosus glycine receptor subunit alpha 1 0.0328793 0.00961403 0.0095896
Leishmania major hypothetical protein, unknown function 0.0068986 0.000732728 0.00477189
Loa Loa (eye worm) hypothetical protein 0.158537 0.0525691 0.06045
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0140244 0.00316862 0.017935
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0306758 0.00886077 0.061549
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0251146 0.00695975 0.074642
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.082362 0.0265293 0.294252
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0266621 0.00748875 0.0517816
Loa Loa (eye worm) hypothetical protein 0.0298168 0.00856715 0.00982775
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0103383 0.00190857 0.0108029
Onchocerca volvulus 0.12315 0.0404724 0.495663
Brugia malayi protein kinase C II. 0.0210902 0.00558402 0.0384739
Schistosoma mansoni neuropeptide receptor 0.521578 0.176672 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0326435 0.00953342 0.0749682
Plasmodium falciparum plasmepsin IX 0.00868516 0.00134345 0.0123633
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0117129 0.00237844 0.0794195
Echinococcus multilocularis atrial natriuretic peptide receptor 0.00519113 0.000149044 0.0000717666
Schistosoma mansoni hypothetical protein 0.12315 0.0404724 0.229082
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0407076 0.0122901 0.0122657
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0125716 0.00267201 0.00304565
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.00869785 0.00134779 0.00605028
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0291589 0.00834224 0.0577447
Echinococcus granulosus nAChR subunit 0.0266621 0.00748875 0.00746427
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0113748 0.00226288 0.0152701
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.00911274 0.00148961 0.0139992
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081147 0.00114844 0.00748386
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.0103383 0.00190857 0.00216734
Trypanosoma cruzi hypothetical protein, conserved 0.0113748 0.00226288 0.0154605
Brugia malayi Adenosine/AMP deaminase family protein 0.082362 0.0265293 0.184812
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0630373 0.0199233 0.256156
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.046318 0.014208 0.0804199
Schistosoma mansoni hypothetical protein 0.00659567 0.000629176 0.00356126
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0143634 0.00328453 0.022408
Loa Loa (eye worm) hypothetical protein 0.0630373 0.0199233 0.0228925
Echinococcus granulosus thymidylate synthase 0.156048 0.0517183 0.0516949
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Echinococcus multilocularis sodium channel protein 0.070721 0.0225499 0.0224744
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0158693 0.00379931 0.026193
Loa Loa (eye worm) hypothetical protein 0.148653 0.0491905 0.0565631
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus potassium voltage gated channel protein 0.00702188 0.000774871 0.000750223
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0220095 0.00589829 0.00587377
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0178995 0.0044933 0.025433
Schistosoma mansoni voltage-gated potassium channel 0.0103383 0.00190857 0.0108029
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0117997 0.00240813 0.00238352
Echinococcus granulosus methionine synthase reductase 0.0102515 0.00187889 0.00185427
Trypanosoma cruzi AMP deaminase, putative 0.231015 0.0773453 0.539937
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Loa Loa (eye worm) hypothetical protein 0.292414 0.0983339 0.1131
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0113748 0.00226288 0.0140552
Loa Loa (eye worm) hypothetical protein 0.0308721 0.00892788 0.0102427
Loa Loa (eye worm) AGC/NDR protein kinase 0.00641896 0.000568767 0.000625964
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0251146 0.00695975 0.0482697
Trichomonas vaginalis CMGC family protein kinase 0.0194327 0.00501741 0.180011
Giardia lamblia Heat shock protein HSP 90-alpha 0.0279476 0.00792816 0.227125
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Echinococcus granulosus dihydrofolate reductase 0.186928 0.0622745 0.0622513
Leishmania major dihydrofolate reductase-thymidylate synthase 0.266822 0.0895856 0.625439
Plasmodium falciparum phosphodiesterase gamma, putative 0.0113748 0.00226288 0.0226538
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.00578628 0.000352491 0.0033769
Leishmania major C-8 sterol isomerase-like protein 0.146825 0.0485655 0.3389
Echinococcus multilocularis GPCR, family 2 0.0171889 0.00425039 0.00417343
Echinococcus multilocularis g protein coupled receptor 0.12315 0.0404724 0.0403983
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0226538
Schistosoma mansoni serine/threonine protein kinase 0.0201596 0.0052659 0.029806
Echinococcus multilocularis NMDA receptor 0.00657698 0.000622786 0.000545545
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis allatostatin A receptor 0.12315 0.0404724 0.0403983
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Onchocerca volvulus 0.00868516 0.00134345 0.0155363
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.00869785 0.00134779 0.00127061
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0737154 0.0235735 0.133431
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0340814 0.010025 0.0696812
Schistosoma mansoni hypothetical protein 0.0298168 0.00856715 0.0484918
Onchocerca volvulus 0.0266621 0.00748875 0.0909414
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0117997 0.00240813 0.00233103
Brugia malayi flavodoxin family protein 0.0158693 0.00379931 0.0260047
Loa Loa (eye worm) hypothetical protein 0.0705782 0.0225011 0.0258582
Mycobacterium tuberculosis Hypothetical protein 0.0742363 0.0237516 0.194677
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0081147 0.00114844 0.00748386
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.423681 0.143207 0.164724
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0103383 0.00190857 0.0615087
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Echinococcus granulosus carbonic anhydrase 0.0081147 0.00114844 0.0011238
Loa Loa (eye worm) hypothetical protein 0.22144 0.074072 0.0851882
Schistosoma mansoni tyrosine kinase 0.00650175 0.000597069 0.00337953
Trichomonas vaginalis conserved hypothetical protein 0.0114372 0.00228421 0.0758277
Onchocerca volvulus 0.0266621 0.00748875 0.0909414
Echinococcus multilocularis cGMP dependent protein kinase 1 0.00545379 0.000238831 0.000161561
Echinococcus multilocularis voltage dependent calcium channel 0.0964222 0.0313357 0.0312609
Brugia malayi Immunoglobulin I-set domain containing protein 0.0215059 0.00572613 0.0394667
Brugia malayi Protein kinase domain containing protein 0.0194327 0.00501741 0.0345151
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0251146 0.00695975 0.00693525
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0265031 0.00743438 0.0420801
Loa Loa (eye worm) hypothetical protein 0.0295615 0.00847986 0.00972732
Schistosoma mansoni memapsin-2 (A01 family) 0.11756 0.0385614 0.218265
Echinococcus multilocularis activated cdc42 kinase 1 0.0836518 0.0269703 0.026895
Leishmania major spermidine synthase 0.0371552 0.0110757 0.0770211
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.266822 0.0895856 1
Plasmodium falciparum plasmepsin V 0.00868516 0.00134345 0.0123633
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.070721 0.0225499 0.0225258
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0113748 0.00226288 0.0154605
Schistosoma mansoni hypothetical protein 0.0171889 0.00425039 0.0240581
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.266822 0.0895856 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Onchocerca volvulus 0.156048 0.0517183 0.633654
Leishmania major p450 reductase, putative 0.0158693 0.00379931 0.026193
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.00869785 0.00134779 0.0124118
Echinococcus granulosus acetylcholinesterase 0.0178995 0.0044933 0.00446875
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0143634 0.00328453 0.0185911
Onchocerca volvulus 0.082362 0.0265293 0.324576
Echinococcus granulosus tm gpcr rhodopsin 2.93008 1 1
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0714326 0.0227932 0.0227177
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0117997 0.00240813 0.0292642
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis neuropeptide receptor 0.12315 0.0404724 0.0403983
Echinococcus granulosus neuropeptide s receptor 0.443883 0.150113 0.150092
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0279476 0.00792816 0.0614529
Trypanosoma brucei adenosine kinase, putative 0.00810491 0.0011451 0.00623602
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Loa Loa (eye worm) hypothetical protein 0.00519113 0.000149044 0.000143091
Onchocerca volvulus 0.12315 0.0404724 0.495663
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0205806 0.00540981 0.0372567
Trypanosoma cruzi AMP deaminase 2, putative 0.082362 0.0265293 0.18497
Loa Loa (eye worm) hypothetical protein 0.0737154 0.0235735 0.0270919
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.231015 0.0773453 0.539937
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus orexin receptor type 2 0.12315 0.0404724 0.0404488
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0823619 0.0265293 0.0264541
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0103383 0.00190857 0.00188395
Schistosoma mansoni voltage-gated potassium channel 0.00702188 0.000774871 0.00438592
Trichomonas vaginalis heat shock protein, putative 0.0150307 0.00351261 0.122652
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0083288 0.00122163 0.00114444
Loa Loa (eye worm) latrophilin receptor protein 2 0.0171889 0.00425039 0.00486151
Echinococcus multilocularis carbonic anhydrase 0.0081147 0.00114844 0.00107124
Schistosoma mansoni endoplasmin 0.0366454 0.0109015 0.0617044
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.156048 0.0517183 0.625309
Chlamydia trachomatis cytosol aminopeptidase 0.0277117 0.00784754 0.106682
Mycobacterium ulcerans short chain dehydrogenase 0.0326435 0.00953342 0.0749682
Echinococcus multilocularis voltage gated potassium channel 0.012826 0.00275897 0.00268189
Echinococcus granulosus shaker cognate 0.00702188 0.000774871 0.000750223
Trichomonas vaginalis conserved hypothetical protein 0.0113748 0.00226288 0.0750144
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0103194 0.0019021 0.00182496
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Loa Loa (eye worm) hypothetical protein 0.0169106 0.00415525 0.00475205
Echinococcus granulosus fatty acid amide hydrolase 1 0.0104602 0.00195022 0.0019256
Echinococcus granulosus transient receptor potential cation channel 0.0068986 0.000732728 0.000708079
Trichomonas vaginalis AGC family protein kinase 0.00641896 0.000568767 0.0104384
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0113748 0.00226288 0.0154605
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0201596 0.0052659 0.00518901
Echinococcus granulosus glycine receptor subunit alpha 1 0.0328793 0.00961403 0.0095896
Echinococcus granulosus activated cdc42 kinase 1 0.0836518 0.0269703 0.0269463
Schistosoma mansoni serine/threonine protein kinase 0.00641896 0.000568767 0.00321934
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0113748 0.00226288 0.0128083
Leishmania major heat shock protein 83-1 0.0366454 0.0109015 0.0758039
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.00869785 0.00134779 0.0076539
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0737154 0.0235735 0.133431
Schistosoma mansoni neurotransmitter gated ion channel 0.0143634 0.00328453 0.0185911
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.10035 0.0326785 0.363076
Schistosoma mansoni opsin-like receptor 0.12315 0.0404724 0.229082
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.184303 0.0613772 0.061354
Loa Loa (eye worm) hypothetical protein 0.0158693 0.00379931 0.00434256
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.00869785 0.00134779 0.00605028
Trypanosoma brucei hypothetical protein, conserved 0.0113748 0.00226288 0.0140552
Schistosoma mansoni plexin 0.00499146 0.0000807884 0.000457279
Echinococcus granulosus voltage dependent calcium channel 0.0964222 0.0313357 0.0313118
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0104602 0.00195022 0.016169
Loa Loa (eye worm) GABA receptor subunit 0.0205806 0.00540981 0.00619536
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0113748 0.00226288 0.0140552
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122987 0.00257871 0.0174767
Loa Loa (eye worm) pre-B cell enhancing factor 0.0387305 0.0116142 0.0133333
Echinococcus granulosus heat shock protein 90 0.0366454 0.0109015 0.0108771
Schistosoma mansoni adenosine kinase 0.00810491 0.0011451 0.00648149
Mycobacterium tuberculosis 4,9-DHSA hydrolase 0.354047 0.119403 1
Schistosoma mansoni apoptosis regulator bax 0.0298168 0.00856715 0.0484918
Trypanosoma brucei heat shock protein, putative 0.0366454 0.0109015 0.0744848
Schistosoma mansoni aryl hydrocarbon receptor 0.0111054 0.00217078 0.012287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.184303 0.0613772 0.0613046
Loa Loa (eye worm) hypothetical protein 0.0266621 0.00748875 0.00858709
Schistosoma mansoni hypothetical protein 0.0762652 0.0244452 0.138365
Onchocerca volvulus 0.00997267 0.00178358 0.0209369
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0113748 0.00226288 0.00223827
Plasmodium falciparum adenosine deaminase 0.082362 0.0265293 0.294252
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0661519 0.020988 0.146097
Schistosoma mansoni heat shock protein 0.0366454 0.0109015 0.0617044
Brugia malayi Carboxylesterase family protein 0.0178995 0.0044933 0.0308533
Echinococcus granulosus potassium voltage gated channel subfamily D 0.00820552 0.00117949 0.00115485
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.00869785 0.00134779 0.00132316
Plasmodium vivax hypothetical protein, conserved 0.00869785 0.00134779 0.0117915
Trichomonas vaginalis conserved hypothetical protein 0.0117129 0.00237844 0.0794195
Echinococcus granulosus sodium and chloride dependent glycine 0.0737154 0.0235735 0.0235495
Plasmodium vivax heat shock protein 90, putative 0.0150307 0.00351261 0.0360361
Toxoplasma gondii heat shock protein 90, putative 0.0366454 0.0109015 0.11934
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0113748 0.00226288 0.0226538
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0266621 0.00748875 0.00741204
Loa Loa (eye worm) hypothetical protein 2.54758 0.869246 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0265031 0.00743438 0.0515852
Trypanosoma cruzi cytochrome P450, putative 0.00917279 0.00151015 0.0102024
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0068986 0.000732728 0.00414739
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0113748 0.00226288 0.0128083
Brugia malayi follicle stimulating hormone receptor 0.12315 0.0404724 0.282228
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.12315 0.0404724 0.0403983
Trypanosoma brucei C-8 sterol isomerase, putative 0.146825 0.0485655 0.337956
Schistosoma mansoni voltage-gated cation channel 0.0964222 0.0313357 0.177366
Brugia malayi hypothetical protein 0.0122987 0.00257871 0.0174767
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0068986 0.000732728 0.00457939
Giardia lamblia Rab geranylgeranyltransferase 0.0630373 0.0199233 0.641145
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0707933 0.0225747 0.290501
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0265031 0.00743438 0.00852455
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081147 0.00114844 0.00748386
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00868516 0.00134345 0.0076042
Loa Loa (eye worm) hypothetical protein 0.0143634 0.00328453 0.00375033
Echinococcus multilocularis endoplasmin 0.0279476 0.00792816 0.00785149
Plasmodium falciparum heat shock protein 90, putative 0.0150307 0.00351261 0.0366413
Brugia malayi hypothetical protein 0.00868516 0.00134345 0.00884632
Brugia malayi hypothetical protein 0.0372574 0.0111107 0.0770868
Schistosoma mansoni nAChR subunit 0.0266621 0.00748875 0.0423878
Trypanosoma brucei Aminopeptidase M1, putative 0.0714326 0.0227932 0.157671
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0103383 0.00190857 0.0108029
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) amidase 0.0104602 0.00195022 0.00221526
Trypanosoma cruzi hypothetical protein, conserved 0.0117997 0.00240813 0.0164751
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Leishmania major carbonic anhydrase-like protein 0.0265031 0.00743438 0.0515852
Brugia malayi Receptor family ligand binding region containing protein 0.00650175 0.000597069 0.00363158
Brugia malayi hypothetical protein 0.0122987 0.00257871 0.0174767
Echinococcus granulosus leukotriene A 4 hydrolase 0.0251146 0.00695975 0.00693525
Echinococcus granulosus 7tm_1 domain containing protein 0.12315 0.0404724 0.0404488
Schistosoma mansoni cathepsin D (A01 family) 0.0560097 0.017521 0.0991723
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.00565359 0.000307131 0.000282472
Trypanosoma brucei rac serine-threonine kinase, putative 0.00641896 0.000568767 0.0022044
Loa Loa (eye worm) hypothetical protein 0.0122987 0.00257871 0.00293832
Toxoplasma gondii hypothetical protein 0.0737154 0.0235735 0.26117
Loa Loa (eye worm) apoptosis regulator protein 0.0298168 0.00856715 0.00982775
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Trypanosoma brucei Sterol methyltransferase, putative 0.00784669 0.00105683 0.00561854
Loa Loa (eye worm) aminopeptidase N 0.0714326 0.0227932 0.0261942
Echinococcus multilocularis fmrfamide receptor 0.12315 0.0404724 0.0403983
Schistosoma mansoni rhodopsin-like orphan GPCR 0.12315 0.0404724 0.229082
Onchocerca volvulus 0.0194327 0.00501741 0.0606171
Brugia malayi hypothetical protein 0.12315 0.0404724 0.282228
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.00519717 0.000151107 0.000145465
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.00868516 0.00134345 0.0123633
Trichomonas vaginalis protein phosphatase type 2C, putative 0.0151187 0.0035427 0.123799
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.00784669 0.00105683 0.00703584
Onchocerca volvulus 0.0737154 0.0235735 0.288308
Echinococcus multilocularis conserved hypothetical protein 0.169758 0.0564052 0.0563322
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0113748 0.00226288 0.0750144
Trypanosoma brucei hypothetical protein, conserved 0.0117997 0.00240813 0.0150713
Schistosoma mansoni voltage-gated potassium channel 0.0068986 0.000732728 0.00414739
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.00869785 0.00134779 0.0129537
Echinococcus multilocularis short transient receptor potential channel 6 0.0068986 0.000732728 0.000655496
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.046318 0.014208 0.0989009
Loa Loa (eye worm) hypothetical protein 0.132765 0.0437592 0.0503147
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0737154 0.0235735 0.164161
Loa Loa (eye worm) AGC/PKN protein kinase 0.00641896 0.000568767 0.000625964
Loa Loa (eye worm) hypothetical protein 0.00820552 0.00117949 0.00132857
Toxoplasma gondii hypothetical protein 0.0737154 0.0235735 0.26117
Loa Loa (eye worm) hypothetical protein 0.12315 0.0404724 0.0465333
Echinococcus granulosus g protein coupled receptor 0.12315 0.0404724 0.0404488
Schistosoma mansoni glutamate receptor kainate 0.0177729 0.00445003 0.0251881
Schistosoma mansoni amidase 0.0823619 0.0265293 0.150161
Loa Loa (eye worm) hypothetical protein 0.012826 0.00275897 0.00314569
Plasmodium falciparum plasmepsin IV 0.0220095 0.00589829 0.0633427
Echinococcus granulosus calcium activated potassium channel 0.00891268 0.00142123 0.0013966
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.00917279 0.00151015 0.00741721
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0158693 0.00379931 0.026193
Trypanosoma cruzi spermidine synthase, putative 0.0371552 0.0110757 0.0770211
Echinococcus granulosus rhodopsin orphan GPCR 0.12315 0.0404724 0.0404488
Plasmodium vivax aspartyl proteinase, putative 0.0220095 0.00589829 0.0627543
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.292414 0.0983339 0.556589
Schistosoma mansoni hypothetical protein 0.0171889 0.00425039 0.0240581
Loa Loa (eye worm) sema domain-containing protein 0.00498121 0.000077283 0.0000605335
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.022964 0.00622458 0.00620007
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0964222 0.0313357 0.0313118
Trypanosoma brucei spermidine synthase 0.0371552 0.0110757 0.0757037
Brugia malayi hypothetical protein 0.0122987 0.00257871 0.0174767
Toxoplasma gondii hypothetical protein 0.0512376 0.0158897 0.17517
Onchocerca volvulus AMP deaminase 2 homolog 0.231015 0.0773453 0.948107
Mycobacterium tuberculosis Two component sensor kinase MprB 0.00869785 0.00134779 0.00605028
Loa Loa (eye worm) hypothetical protein 0.0068986 0.000732728 0.000814594
Loa Loa (eye worm) TOPoisomerase family member 0.00869785 0.00134779 0.00152219
Echinococcus granulosus serotonin transporter 0.243387 0.0815745 0.0815518
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0122987 0.00257871 0.00255411
Echinococcus multilocularis hyperpolarization activated cyclic 0.0103383 0.00190857 0.00183142
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0266621 0.00748875 0.00746427
Leishmania major nicotinate phosphoribosyltransferase, putative 0.00705803 0.000787229 0.0051526
Echinococcus multilocularis heat shock protein 0.0366454 0.0109015 0.010825
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0117129 0.00237844 0.0794195
Echinococcus multilocularis sodium and chloride dependent glycine 0.0737154 0.0235735 0.0234981
Onchocerca volvulus 0.0117997 0.00240813 0.0286003
Loa Loa (eye worm) hypothetical protein 0.00509187 0.000115113 0.000104055
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0964222 0.0313357 0.177366
Loa Loa (eye worm) glutamate receptor 2 0.0177729 0.00445003 0.00509119
Brugia malayi Protein kinase domain containing protein 0.00641896 0.000568767 0.00343385
Brugia malayi Tachykinin-like peptides receptor 99D 0.12315 0.0404724 0.282228
Schistosoma mansoni acetylcholine receptor subunit beta 0.0122987 0.00257871 0.014596
Schistosoma mansoni hypothetical protein 0.0171889 0.00425039 0.0240581
Onchocerca volvulus 0.12315 0.0404724 0.495663
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.00869785 0.00134779 0.0401331
Loa Loa (eye worm) hypothetical protein 0.00519113 0.000149044 0.000143091
Mycobacterium ulcerans amidase 0.0104602 0.00195022 0.0111223
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0158693 0.00379931 0.0248031
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0266621 0.00748875 0.0517816
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0226639 0.00612199 0.222116
Echinococcus granulosus potassium voltage gated channel protein 0.0068986 0.000732728 0.000708079
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.00705803 0.000787229 0.00133071
Leishmania major cytochrome p450-like protein 0.00659567 0.000629176 0.00404854
Entamoeba histolytica protein kinase, putative 0.00641896 0.000568767 0.00543709

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = -0.8 % Agonist activity at human recombinant dopamine D1 receptor expressed in CHOK1 cells assessed as stimulation of cAMP accumulation at 100 uM after 30 mins by HTRF assay relative to SKF81297 ChEMBL. 24088053
Activity (binding) = 3.6 % Agonist activity at human recombinant dopamine D2 long receptor expressed in CHOK1 cells coexpressing mitochondrial apoaequorin at 100 uM by luminometric analysis relative to quinpirol ChEMBL. 24088053
EC50 (functional) = 0.362 uM Antiviral activity against influenza A/Hong Kong/7/87 (H3N2) in MDCK cells assessed as inhibition of virus-induced cytopathic effect by MTS assay ChEMBL. 17588747
IC50 (binding) DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CXCR1 (IL-8A) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Calcitonin radioligand binding (ligand: [125I] Calcitonin (salmon)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase PKCalpha enzyme inhibition (substrate: Histone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
IC50 (functional) = 35.6 nM Antimalarial activity against liver stages of Plasmodium yoelii yoelii ChEMBL. 22122518
IC50 (functional) = 35.6 nM Antimicrobial activity against Plasmodium yoelii 265 liver infected in mammalian hepatocytes after 48 hrs ChEMBL. 18212104
IC50 (binding) = 4.4 uM Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay ChEMBL. 23241029
IC50 (functional) = 7 uM Antiparasitic activity against Trypanosoma brucei 427 bloodstream forms assessed as inhibition of parasite growth after 48 hrs ChEMBL. 20805012
IC50 (functional) = 7 uM Antitrypanosomal activity against Trypanosoma brucei ChEMBL. 21542562
IC50 (functional) = 7.04 uM Antiparasitic activity against Trypanosoma brucei 221 blood stream form at pH 7.4 ChEMBL. 17588747
IC50 (functional) = 7.04 uM Antiparasitic activity against Trypanosoma brucei 221 blood stream form at pH 7.4 ChEMBL. 17588747
IC50 (functional) = 7.04 uM Antitrypanosomal activity against Trypanosoma brucei 427 assessed as parasite growth inhibition after 48 hrs ChEMBL. 19251424
IC50 (functional) = 7.04 uM Trypanocidal activity against Trypanosoma brucei 427 blood stream after 48 hrs by hemocytometer ChEMBL. 18954995
IC50 (functional) = 7.04 uM Trypanocidal activity against Trypanosoma brucei 427 bloodstream form assessed as decrease in cell density after 48 hrs by hemocytometry ChEMBL. 19954985
IC50 (functional) = 7.04 uM Antitrypanosomal activity against bloodstream form of Trypanosoma brucei 427 after 48 hrs by hemocytometer analysis ChEMBL. 22178660
IC50 (functional) = 7.04 uM Antitrypanosomal activity against Trypanosoma brucei Lister 427 after 2 days by Alamar Blue fluorescence assay ChEMBL. No reference
IC50 (binding) = 7.3 uM Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay ChEMBL. 23241029
IC50 (binding) = 288 uM Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay ChEMBL. 23241029
IC90 (functional) = 13.97 uM Antiparasitic activity against Trypanosoma brucei 221 blood stream form at pH 7.4 ChEMBL. 17588747
IC90 (functional) = 13.97 uM Antiparasitic activity against Trypanosoma brucei 221 blood stream form at pH 7.4 ChEMBL. 17588747
IC90 (functional) = 13.97 uM Antitrypanosomal activity against Trypanosoma brucei 427 assessed as parasite growth inhibition after 48 hrs ChEMBL. 19251424
IC90 (functional) = 13.97 uM Trypanocidal activity against Trypanosoma brucei 427 blood stream after 48 hrs by hemocytometer ChEMBL. 18954995
IC90 (functional) = 13.97 uM Trypanocidal activity against Trypanosoma brucei 427 bloodstream form assessed as decrease in cell density after 48 hrs by hemocytometry ChEMBL. 19954985
IC90 (functional) = 13.97 uM Antitrypanosomal activity against bloodstream form of Trypanosoma brucei 427 after 48 hrs by hemocytometer analysis ChEMBL. 22178660
IC90 (functional) = 13.97 uM Antitrypanosomal activity against Trypanosoma brucei Lister 427 after 2 days by Alamar Blue fluorescence assay ChEMBL. No reference
IC90 (functional) = 14 uM Antiparasitic activity against Trypanosoma brucei 427 bloodstream forms assessed as inhibition of parasite growth after 48 hrs ChEMBL. 20805012
ID50 (functional) > 4 ng ml-1 Antiviral activity against influenza A virus (NY/83/R6) in Madin Darby canine kidney (MDCK) cell culture ChEMBL. 2362279
ID50 (functional) = 9.8 ng ml-1 Antiviral activity against influenza A virus (Taiwan) in Madin Darby canine kidney (MDCK) cell culture ChEMBL. 2362279
ID50 (functional) > 10 ng ml-1 Antiviral activity against influenza B virus (Ann Arbor) in Madin Darby canine kidney (MDCK) cell culture ChEMBL. 2362279
ID50 (functional) = 12 ng ml-1 Antiviral activity against influenza A virus (NY/83/5) in Madin Darby canine kidney (MDCK) cell culture ChEMBL. 2362279
ID50 (functional) = 21 ng ml-1 Antiviral activity against influenza A virus (Mississippi) in Madin Darby canine kidney (MDCK) cell culture ChEMBL. 2362279
Inhibition (functional) = -0.4 % Antagonist activity at human recombinant dopamine D1 receptor expressed in CHOK1 cells assessed as inhibition of agonist-induced cAMP accumulation at 100 uM preincubated for 10 mins prior to agonist addition measured after 30 mins by HTRF assay relative to SCH23390 ChEMBL. 24088053
Inhibition (binding) = 41 % Antagonist activity at human recombinant dopamine D2 long receptor expressed in CHOK1 cells coexpressing mitochondrial apoaequorin assessed as inhibition of agonist-induced effect at 50 uM after 15 mins by luminometric analysis relative to haloperidol ChEMBL. 24088053
Inhibition (binding) = 74 % Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells at 20 uM after 1.5 mins by fluorescence assay ChEMBL. 23241029
Kd (binding) = 0.016 uM Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometry ChEMBL. 20570509
Ki (binding) DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Calcitonin radioligand binding (ligand: [125I] Calcitonin (salmon)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) ChEMBL. No reference
Ki (binding) DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase PKCalpha enzyme inhibition (substrate: Histone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CXCR1 (IL-8A) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) ChEMBL. No reference
LD50 (ADMET) = 175 mg kg-1 Acute toxicity in sc dosed Balb/c mouse after 5 days ChEMBL. 23489622
MCC (ADMET) > 100 uM Cytotoxicity against MDCK cells assessed as changes in cell morphology ChEMBL. 17588747
MIC50 (functional) < 0.14 ug ml-1 Antiviral activity against influenza A,H2N2 virus infected MDCK cell lines. ChEMBL. 8765514
MIC50 (functional) > 12 ug ml-1 Antiviral activity against influenza A,H3N2 virus infected MDCK cell lines. ChEMBL. 8765514
MIC50 (functional) > 20 ug ml-1 Antiviral activity against influenza B virus infected MDCK cell lines. ChEMBL. 8765514
MIC50 (functional) = 28 ug ml-1 Antiviral activity tested against influenza A,H1N1 virus infected MDCK cell lines. ChEMBL. 8765514
MIC50 (functional) = 250 ug ml-1 Antiviral activity of compound was tested against morphology virus infec+ted MDCK cell lines. ChEMBL. 8765514
MIC50 (functional) = 20.9 uM Anti-influenza virus activity was evaluated in Madin-Darby canine kidney (MDCK) cells against influenza A H2N2 strain (A2 Japan/305/57) ChEMBL. 10617092
MIC50 (functional) > 56 uM Anti-influenza virus activity was evaluated in Madin-Darby canine kidney (MDCK) cells against influenza A H3N2 (X31) ChEMBL. 10617092
MIC50 (functional) > 93 uM Anti-influenza virus activity was evaluated in Madin-Darby canine kidney (MDCK) cells against influenza B (Hong Kong/5/72) ChEMBL. 10617092
MTC50 (functional) = 1160 uM Concentration required to reduce the viability of MDCK cells ChEMBL. 10617092
Potency (functional) 23.7781 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Ratio (functional) > 276 Selectivity index, ratio of EC50 for influenza A/Hong Kong/7/87 (H3N2) to MCC for MDCK cells ChEMBL. 17588747
T1/2 (ADMET) = 24 hr Half life in human plasma ChEMBL. 21354674

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium yoelii 18212104
Trypanosoma brucei ChEMBL23 17588747
Trypanosoma brucei gambiense 17588747

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 49870  
Annotator: millerja@u.washington.edu Comment: Note: manuscript suggested mode of action against proton-translocating, membrane-localized ATPases (H+-ATPases); surveyed GeneDB and selected four genes that most closely matched this description. Link perhaps too weak to include? References: 10103219
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 44272  
Annotator: millerja@u.washington.edu Comment: Note: manuscript suggested mode of action against proton-translocating, membrane-localized ATPases (H+-ATPases); surveyed GeneDB and selected four genes that most closely matched this description. Link perhaps too weak to include? References: 10103219
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 31958  
Annotator: millerja@u.washington.edu Comment: Note: manuscript suggested mode of action against proton-translocating, membrane-localized ATPases (H+-ATPases); surveyed GeneDB and selected four genes that most closely matched this description. Link perhaps too weak to include? References: 10103219

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

7 literature references were collected for this gene.

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