Detailed information for compound 1022500

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 773.952 | Formula: C41H63N3O11
  • H donors: 2 H acceptors: 4 LogP: 4.77 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC[C@H]1OC(=O)[C@H](C)[C@H]2OC/C(=N/OCc3ccccc3)/CCO[C@@]([C@@H]([C@H]2C)O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)(C[C@H](C(=O)[C@@H]([C@@H]2[C@]1(C)OC(=O)N2)C)C)C
  • InChi: 1S/C41H63N3O11/c1-11-31-41(8)35(42-39(48)55-41)25(4)32(45)23(2)20-40(7)36(54-38-33(46)30(44(9)10)19-24(3)52-38)26(5)34(27(6)37(47)53-31)49-22-29(17-18-50-40)43-51-21-28-15-13-12-14-16-28/h12-16,23-27,30-31,33-36,38,46H,11,17-22H2,1-10H3,(H,42,48)/b43-29+/t23-,24-,25+,26+,27-,30+,31-,33-,34+,35-,36-,38+,40-,41-/m1/s1
  • InChiKey: PWDAZEBIOZXQRY-PTVPDWDMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Brugia malayi Ets-domain containing protein 0.0077 0.0127 0.0558
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0075 0.338
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0066 0.0964
Brugia malayi RNA, U transporter 1 0.0162 0.0299 0.131
Echinococcus granulosus Dipeptidyl peptidase 9 0.0352 0.0682 0.1484
Schistosoma mansoni ran 0.0042 0.0056 0.0119
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0386
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Echinococcus multilocularis tumor protein p63 0.1036 0.2066 0.2065
Brugia malayi jmjC domain containing protein 0.0093 0.0159 0.0695
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0086 0.124
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Echinococcus multilocularis geminin 0.0664 0.1314 0.1312
Loa Loa (eye worm) steroid hormone receptor 0.005 0.0072 0.0317
Schistosoma mansoni smad1 5 8 and 0.0026 0.0023 0.0047
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0352 0.0682 1
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.0127 0.0273
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.0278 0.0603
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0024 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-41 0.005 0.0072 0.0317
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.1451 0.2905 1
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0005 0.0019
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.0188
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0015 0.0002 0.0009
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0058 0.0123
Mycobacterium ulcerans AcrR family transcriptional regulator 0.1451 0.2905 1
Echinococcus multilocularis lamin 0.0135 0.0244 0.0242
Brugia malayi MH2 domain containing protein 0.0026 0.0023 0.01
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0195 0.2861
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Echinococcus multilocularis expressed protein 0.0018 0.0008 0.0006
Brugia malayi Importin beta-1 subunit 0.0057 0.0086 0.0378
Loa Loa (eye worm) TAR-binding protein 0.02 0.0376 0.1648
Schistosoma mansoni synaptojanin 0.0015 0.0002 0.0002
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0019 0.0082
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0352 0.0682 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.3095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.005 0.0072 0.0155
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0058 0.0238
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0049 0.0092
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0002 0.0008
Brugia malayi hypothetical protein 0.0026 0.0024 0.0107
Loa Loa (eye worm) hypothetical protein 0.0269 0.0514 0.2253
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0022
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0689 0.1364 0.4691
Leishmania major cathepsin L-like protease 0.0064 0.0099 0.1458
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0009
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0006 0.0094
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1046 0.2085 0.4549
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0195 0.0799
Brugia malayi ecdysone receptor 0.0024 0.0019 0.0082
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0018 0.0008 0.0012
Echinococcus granulosus prolyl endopeptidase 0.0083 0.0139 0.0298
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0154 0.0282 0.028
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0023 0.033
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0023 0.0071
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0019 0.0036
Echinococcus multilocularis Smad4 0.0026 0.0023 0.0021
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.0245
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0123 0.0219 0.0473
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0063 0.0061
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0083 0.0139 0.2032
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0005 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0043 0.0189
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0189 0.041
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0423 0.0827 0.18
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0024 0.0107
Schistosoma mansoni neutral sphingomyelinase 0.0015 0.0002 0.0002
Schistosoma mansoni alpha-glucosidase 0.015 0.0274 0.0595
Entamoeba histolytica hypothetical protein, conserved 0.0083 0.0139 0.2489
Brugia malayi hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Onchocerca volvulus 0.0135 0.0244 0.0998
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0219 0.0896
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1143 0.2282 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.005
Trypanosoma cruzi oligopeptidase b 0.0083 0.0139 0.2032
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0022
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0083 0.0139 0.03
Onchocerca volvulus 0.0024 0.0019 0.0077
Loa Loa (eye worm) hypothetical protein 0.0063 0.0098 0.0428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Schistosoma mansoni jumonji domain containing protein 0.0074 0.012 0.0259
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0005 0.0019
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0006 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0066 0.1181
Schistosoma mansoni transcription factor LCR-F1 0.029 0.0557 0.1212
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0011 0.0009
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0001 0.0005
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0352 0.0682 1
Echinococcus multilocularis lamin dm0 0.0135 0.0244 0.0242
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0005 0.0006
Onchocerca volvulus 0.0047 0.0066 0.0269
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0042 0.2287
Schistosoma mansoni synaptojanin 0.0015 0.0002 0.0002
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0008 0.0014
Brugia malayi Pre-SET motif family protein 0.1074 0.2142 0.9386
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Toxoplasma gondii ABC1 family protein 0.0108 0.0189 0.275
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0056 0.0054
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0075 0.016
Brugia malayi RNA recognition motif domain containing protein 0.02 0.0376 0.1648
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0023 0.0071
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0176 1
Echinococcus multilocularis protein dispatched 1 0.0047 0.0065 0.0063
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0005 0.0068
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0019 0.0082
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0015 0.0002 0.0029
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.005 0.0072 0.007
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0047 0.0852
Schistosoma mansoni microtubule-associated protein tau 0.0687 0.1359 0.2964
Entamoeba histolytica hypothetical protein 0.0024 0.002 0.0353
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0058 0.1044
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.005 0.0072 0.0317
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0246 0.0533
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0028 0.0057
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Onchocerca volvulus Huntingtin homolog 0.0119 0.0211 0.0865
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0176 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0189 0.0774
Trichomonas vaginalis ran, putative 0.0042 0.0056 0.0229
Loa Loa (eye worm) ctsf protein 0.0017 0.0005 0.002
Echinococcus granulosus ecdysone induced protein 78C 0.005 0.0072 0.0153
Loa Loa (eye worm) hypothetical protein 0.0154 0.0282 0.1237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0139 0.487
Brugia malayi beta-lactamase family protein 0.0108 0.0189 0.0828
Onchocerca volvulus 0.0017 0.0005 0.0019
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.005 0.0072 0.0153
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0019 0.0038
Loa Loa (eye worm) hypothetical protein 0.0063 0.0098 0.0428
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.004 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Echinococcus multilocularis smad 0.0026 0.0023 0.0021
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.2281 0.4583 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0005 0.002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0049 0.088
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0125 0.7058
Echinococcus multilocularis ubiquitin specific protease 41 0.0111 0.0195 0.0193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0423 0.0827 0.1802
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0083 0.0139 0.0607
Schistosoma mansoni intermediate filament proteins 0.0135 0.0244 0.0529
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0042 0.0137
Onchocerca volvulus 0.0018 0.0008 0.0032
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1046 0.2085 0.4547
Brugia malayi G-protein alpha subunit 0.0018 0.0008 0.0034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Loa Loa (eye worm) fli-1 protein 0.0235 0.0445 0.1952
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0247 0.047 0.2058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0423 0.0827 0.1802
Brugia malayi hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni hypothetical protein 0.029 0.0557 0.1212
Loa Loa (eye worm) hypothetical protein 0.0111 0.0195 0.0855
Schistosoma mansoni nuclear receptor 0.0024 0.0019 0.0038
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.0127 0.0558
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0018 0.0008 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0189 0.0774
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0154 0.0282 0.028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0269 0.1181
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0018 0.0008 0.0014
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0018 0.0008 0.0034
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0011 0.002
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0083 0.0139 0.2489
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0024 0.0051
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0018 0.0008 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0072 0.0153
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0023 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.005 0.0072 0.0296
Brugia malayi nuclear hormone receptor 0.005 0.0072 0.0317
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.0189 0.0187
Trypanosoma brucei RNA editing exonuclease 2 0.0015 0.0002 0.0029
Brugia malayi tailless protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0005 0.0068
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0086 0.1266
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0066 0.015
Mycobacterium leprae Probable lipase LipE 0.0108 0.0189 0.0577
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1074 0.2142 0.9386
Mycobacterium ulcerans hypothetical protein 0.0108 0.0189 0.0577
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0002 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0049 0.0201
Echinococcus granulosus FTZ F1 alpha 0.005 0.0072 0.0153
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0043 0.0072
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.2281 0.4583 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0018 0.0008 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0054 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0054 0.022
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.029 0.0557 0.121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.02 0.0376 0.1648
Echinococcus multilocularis tar DNA binding protein 0.02 0.0376 0.0374
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0018 0.0008 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Echinococcus granulosus importin subunit beta 1 0.0057 0.0086 0.0184
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0006 0.001
Brugia malayi Inositol-1 0.0043 0.0058 0.0255
Brugia malayi hypothetical protein 0.0065 0.0103 0.0453
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.004 0.0038
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0019 0.0082
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0101 0.0176 0.0771
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0076 0.0125 0.0123
Echinococcus granulosus Smad4 0.0026 0.0023 0.0045
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0023 0.0045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0066 0.1181
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0064 0.0946
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0006 0.0094
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0066 0.0964
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0066 0.1181
Echinococcus granulosus expressed conserved protein 0.009 0.0152 0.0327
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0006 0.0094
Toxoplasma gondii cathepsin CPL 0.0017 0.0005 0.0039
Brugia malayi Cytochrome P450 family protein 0.0036 0.0043 0.0189
Loa Loa (eye worm) hypothetical protein 0.0066 0.0105 0.0458
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi Serine protease Z688.6 precursor 0.0123 0.0219 0.0959
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0005 0.0153
Brugia malayi Bromodomain containing protein 0.0032 0.0035 0.0154
Brugia malayi steroid hormone receptor 0.005 0.0072 0.0317
Echinococcus granulosus intermediate filament protein 0.0135 0.0244 0.0528
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.002
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0049 0.0069 0.0303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Onchocerca volvulus 0.0015 0.0002 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0058 0.0825
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Brugia malayi Serine protease Z688.6 precursor 0.0123 0.0219 0.0959
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0043 0.0634
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0019 0.0017
Echinococcus granulosus GPCR family 2 0.0078 0.0129 0.0277
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0054 0.0223
Onchocerca volvulus 0.1222 0.2442 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0066 0.015
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0006 0.0095
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0056 0.0819
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0189 0.2771
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0076 0.0125 0.2242
Loa Loa (eye worm) hypothetical protein 0.0078 0.0129 0.0564
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0018 0.0008 0.0006
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.0127 0.0125
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0006 0.0115
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0047 0.2611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Onchocerca volvulus 0.0022 0.0015 0.0061
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0075 0.033
Onchocerca volvulus 0.0135 0.0244 0.0998
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0019 0.0038
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0176 0.2581
Brugia malayi prolyl oligopeptidase family protein 0.0352 0.0682 0.2988
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0083 0.0139 0.03
Loa Loa (eye worm) hypothetical protein 0.0135 0.0244 0.1068
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0288
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.005 0.0072 0.0317
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0042 0.0067
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0006 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Echinococcus multilocularis survival motor neuron protein 1 0.0724 0.1435 0.1433
Brugia malayi nuclear receptor NHR-67 0.0024 0.0019 0.0082
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0015 0.0002 0.0036
Brugia malayi hypothetical protein 0.0026 0.0024 0.0107
Schistosoma mansoni loxhd1 0.002 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0015 0.0002 0.0029
Echinococcus granulosus lamin dm0 0.0135 0.0244 0.0528
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0058 0.0238
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0072 0.1055
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.005 0.0072 0.0317
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0018 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0023 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi nuclear hormone receptor 0.0024 0.0019 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.005 0.0072 0.0317
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0123 0.0219 0.3189
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.0189 0.0577
Onchocerca volvulus 0.0108 0.0189 0.0774
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0054 0.077
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0075 0.1104
Schistosoma mansoni retinoic acid receptor RXR 0.005 0.0072 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0023 0.0071
Loa Loa (eye worm) beta-lactamase 0.0108 0.0189 0.0828
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0075 0.1104
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0195 0.2861
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0083 0.0139 0.2489
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0056
Onchocerca volvulus 0.002 0.0011 0.0046
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0018 0.0008 0.0032
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0076 0.0125 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0028 0.0026
Loa Loa (eye worm) doublecortin family protein 0.002 0.0011 0.005
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0018 0.0008 0.0006
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Trypanosoma brucei oligopeptidase b 0.0083 0.0139 0.2032
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0103 0.0101
Entamoeba histolytica prolyl oligopeptidase family protein 0.0083 0.0139 0.2489
Brugia malayi Nuclear hormone receptor family member nhr-19 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.005 0.0072 0.0155
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Brugia malayi nuclear receptor NHR-88 0.0024 0.0019 0.0082
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0148 0.0271 0.0587
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Schistosoma mansoni hypothetical protein 0.0609 0.1203 0.2622
Schistosoma mansoni ets-related 0.0235 0.0445 0.097
Brugia malayi hypothetical protein 0.0162 0.0299 0.1308
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0056 0.0819
Loa Loa (eye worm) hypothetical protein 0.0152 0.0278 0.1217
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Brugia malayi beta-lactamase family protein 0.0108 0.0189 0.0828
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0015 0.0002 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0019 0.0036
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0088 0.1295
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0019 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0023 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.004 0.0085
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0075 0.1104
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0111 0.0195 0.2861
Brugia malayi latrophilin 2 splice variant baaae 0.0169 0.0312 0.1366
Loa Loa (eye worm) DR-78 0.0024 0.0019 0.0082
Echinococcus granulosus microtubule associated protein 2 0.0687 0.1359 0.2963
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Schistosoma mansoni patched 1 0.0041 0.0054 0.0115
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0123 0.0219 0.0896
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0064 0.0264
Plasmodium falciparum peptidase, putative 0.0083 0.0139 0.7848
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0083 0.0139 0.03
Echinococcus granulosus smad 0.0026 0.0023 0.0045
Leishmania major cytochrome p450-like protein 0.0036 0.0043 0.0634
Plasmodium falciparum phd finger protein, putative 0.0028 0.0028 0.1507
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0019 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.002 0.004
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0018 0.0008 0.0034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0049 0.0215
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0075 0.1104
Giardia lamblia Alanyl dipeptidyl peptidase 0.0083 0.0139 0.6297
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0086 0.1266
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0043 0.0189
Schistosoma mansoni carbon catabolite repressor protein 0.0015 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0139 0.2032
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.2484
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0023 0.033
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0086 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0083 0.0139 0.047
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0058 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0104 0.0181 0.0791
Brugia malayi ecdysteroid receptor 0.005 0.0072 0.0317
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0022
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0024 0.0049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0423 0.0827 0.1802
Echinococcus granulosus tar DNA binding protein 0.02 0.0376 0.0817
Echinococcus multilocularis prolyl endopeptidase 0.0083 0.0139 0.0137
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0005 0.002
Schistosoma mansoni lamin 0.0135 0.0244 0.0529
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0018 0.0008 0.0012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.005 0.0072 0.0153
Plasmodium vivax SET domain protein, putative 0.0154 0.0282 1
Onchocerca volvulus 0.0017 0.0005 0.0019
Toxoplasma gondii hypothetical protein 0.0083 0.0139 0.2008
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0047 0.2095
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.0189 0.0644
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0246 0.0244
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0023 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0189 0.0774
Mycobacterium ulcerans beta-lactamase 0.0108 0.0189 0.0577
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Schistosoma mansoni lamin 0.0135 0.0244 0.0529
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0006 0.0065
Schistosoma mansoni survival motor neuron protein 0.0148 0.0269 0.0586
Brugia malayi MH2 domain containing protein 0.0376 0.0732 0.3206
Brugia malayi CHE-14 protein 0.0041 0.0054 0.0235
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0123 0.0219 0.3931
Mycobacterium tuberculosis Conserved protein 0.0108 0.0189 0.0644
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0023 0.01
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Leishmania major cathepsin L-like protease 0.0064 0.0099 0.1458
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0018 0.0008 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Entamoeba histolytica prolyl oligopeptidase family protein 0.0083 0.0139 0.2489
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0011 0.0536
Brugia malayi Nuclear hormone receptor family member nhr-14 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0076 0.0125 0.0268
Schistosoma mansoni zinc finger protein 0.0024 0.0019 0.0038
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Schistosoma mansoni hypothetical protein 0.0169 0.0312 0.0678
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0075 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.005 0.0072 0.0317
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0111 0.0195 0.0855
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0066 0.015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trichomonas vaginalis Phospholipase C precursor, putative 0.0015 0.0002 0.0008
Echinococcus multilocularis cysteine protease 0.0017 0.0005 0.0003
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0006 0.0004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.005 0.0072 0.0155
Loa Loa (eye worm) intermediate filament protein 0.0135 0.0244 0.1068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.029 0.0557 0.0555
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Schistosoma mansoni Tr4/Tr2 (homologue) 0.005 0.0072 0.0155
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0019 0.0077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0005 0.002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0076 0.0125 0.0423
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0083 0.0139 0.0607
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0189 0.0774
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0111 0.0195 0.0193
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0023 0.01
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0174 0.0323 0.1413
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0018 0.0008 0.0014
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0066 0.022
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0054 0.0113
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0024 0.0022
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0018 0.0008 0.0014
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0015 0.0002 0.0008
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.0072 0.0155
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0189 0.041
Leishmania major RNA-editing complex protein MP100, putative 0.0015 0.0002 0.0029
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Brugia malayi Cytochrome P450 family protein 0.0026 0.0023 0.0099
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi Doublecortin family protein 0.002 0.0011 0.005
Brugia malayi hypothetical protein 0.029 0.0557 0.2439
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Leishmania major GTP-binding protein, putative 0.0042 0.0056 0.0819
Echinococcus granulosus cathepsin l1 0.0017 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Leishmania major cytochrome p450-like protein 0.0026 0.0023 0.033
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0006 0.0115
Brugia malayi conserved hypotetical protein 0.0024 0.0019 0.0082
Brugia malayi exodeoxyribonuclease III family protein 0.0076 0.0125 0.0547
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0015 0.0002 0.0002
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0352 0.0682 1
Loa Loa (eye worm) hypothetical protein 0.0119 0.0211 0.0925
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0083 0.0139 0.0402
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0162 0.0299 0.1308
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Mycobacterium ulcerans transcriptional regulator 0.1451 0.2905 1
Leishmania major importin beta-1 subunit, putative 0.0046 0.0064 0.0946
Entamoeba histolytica prolyl oligopeptidase family protein 0.0083 0.0139 0.2489
Mycobacterium leprae conserved hypothetical protein 0.0108 0.0189 0.0577
Entamoeba histolytica hypothetical protein 0.0046 0.0064 0.1159
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0066 0.015
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0006 0.0095
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Leishmania major cytochrome p450-like protein 0.0026 0.0023 0.033
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Mycobacterium tuberculosis Probable peptidase 0.0083 0.0139 0.047
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0005 0.0153
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0018 0.0008 0.0034
Schistosoma mansoni steroid hormone receptor ad4bp 0.005 0.0072 0.0155
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0117 0.0513
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0015 0.0002 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.005 0.0072 0.0317
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.0038
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0099 0.1458
Brugia malayi Nuclear hormone receptor family member nhr-49 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Trypanosoma brucei glucosidase, putative 0.0039 0.0049 0.0718
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Brugia malayi follicle stimulating hormone receptor 0.1143 0.2282 1
Trypanosoma brucei protein kinase, putative 0.0052 0.0075 0.1104
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0164 0.2941
Loa Loa (eye worm) MH2 domain-containing protein 0.0376 0.0732 0.3206
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.0189 0.0828
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0083 0.0139 0.2032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.2281 0.4583 0.4582
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0111 0.0195 0.0421
Echinococcus granulosus geminin 0.0664 0.1314 0.2863
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0352 0.0682 0.068
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0084
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0011 0.0332
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0075 0.1104
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0288
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni nuclear hormone receptor 0.005 0.0072 0.0155
Mycobacterium tuberculosis Conserved protein 0.0108 0.0189 0.0644
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0129 0.0127
Echinococcus granulosus acylamino acid releasing enzyme 0.0083 0.0139 0.0298
Toxoplasma gondii FATC domain-containing protein 0.0024 0.002 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0049 0.0718
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0099 0.1458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0015 0.0002 0.0029
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0049 0.0215
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0056 0.1921
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0006 0.0094
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.0038
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Brugia malayi prolyl oligopeptidase family protein 0.0083 0.0139 0.0607
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0083 0.0139 0.2032
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0029
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0076 0.0125 0.0547
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.005 0.0072 0.0317
Brugia malayi Ets-domain containing protein 0.0077 0.0127 0.0558
Loa Loa (eye worm) hypothetical protein 0.0724 0.1435 0.6286
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0123 0.0219 0.0896
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.005 0.0072 0.0317
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0154 0.0282 0.0614
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0008 0.0014
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0075 0.1078
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.004 0.0085
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0054 0.0052
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.002 0.0288
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0075 0.1104
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0083 0.0139 0.0567
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0255 0.0253
Plasmodium vivax vivapain-2 0.0017 0.0005 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0006 0.0094
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0189 0.2771
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.005 0.0072 0.0153
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Schistosoma mansoni polycystin 1-related 0.002 0.0011 0.0022
Brugia malayi beta-lactamase 0.0108 0.0189 0.0828
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0049 0.0718
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0139 0.0567
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0002 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.005 0.0072 0.0153
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0123 0.0219 0.3931
Treponema pallidum exodeoxyribonuclease (exoA) 0.0076 0.0125 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0111 0.0195 0.0799
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0072 0.0317
Brugia malayi nuclear receptor RXR 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Toxoplasma gondii exonuclease III APE 0.0076 0.0125 0.1806
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0005 0.0019
Mycobacterium tuberculosis Conserved protein 0.0108 0.0189 0.0644
Echinococcus multilocularis microtubule associated protein 2 0.0687 0.1359 0.1358
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0023 0.033
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0075 0.0162
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.002 0.0288
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0159 0.0157
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0049 0.0201
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0164 0.0162
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0066 0.015
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0123 0.0219 0.3209
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0049 0.0047
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0049 0.088
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Echinococcus granulosus serine protein kinase ATM 0.0024 0.002 0.0039
Schistosoma mansoni smad1 5 8 and 0.0026 0.0023 0.0047
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0023 0.0071
Echinococcus multilocularis FTZ F1 alpha 0.005 0.0072 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.005 0.0072 0.0317
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0066 0.015
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0066 0.015
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0023 0.0071
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0084
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0083 0.0139 0.2008
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0051 0.0049
Leishmania major pantothenate kinase subunit, putative 0.0017 0.0006 0.0086
Loa Loa (eye worm) acetyltransferase 0.014 0.0255 0.1116
Brugia malayi TAR-binding protein 0.02 0.0376 0.1648
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Onchocerca volvulus 0.0017 0.0005 0.0019
Schistosoma mansoni smad1 5 8 and 0.0026 0.0023 0.0047
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Onchocerca volvulus 0.0108 0.0189 0.0774
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0154 0.0282 0.4124
Echinococcus multilocularis cysteine protease 0.0017 0.0005 0.0003
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0023 0.0045
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0189 0.6668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Loa Loa (eye worm) Smad1 0.0026 0.0023 0.01
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0002 0.0029
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0195 0.2861
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0076 0.0125 0.183
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.0189 0.0577
Schistosoma mansoni alpha-glucosidase 0.015 0.0274 0.0595
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma cruzi prolyl endopeptidase 0.0083 0.0139 0.2032
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0028 0.0935
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0075 0.016
Brugia malayi hypothetical protein 0.0101 0.0176 0.0771
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0129 0.0564
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0129 0.0564
Loa Loa (eye worm) hypothetical protein 0.0247 0.047 0.2058
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0019 0.0082
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0247 0.047 0.2058
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0008 0.0014
Brugia malayi hypothetical protein 0.002 0.0011 0.005
Brugia malayi hypothetical protein 0.0724 0.1435 0.6286
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0123 0.0219 0.0475
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.005 0.0072 0.007
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0076 0.0125 0.183
Echinococcus granulosus peregrin 0.0032 0.0035 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0066 0.0288
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Onchocerca volvulus 0.005 0.0072 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-25 0.005 0.0072 0.0317
Loa Loa (eye worm) inositol-1 0.0043 0.0058 0.0255
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0005 0.0003
Onchocerca volvulus 0.0017 0.0005 0.0019
Onchocerca volvulus 0.0017 0.0005 0.0019
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0023 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0023 0.0071
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0066 0.0964
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0006 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni cytochrome P450 0.0026 0.0023 0.0047
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0018 0.0008 0.0012
Echinococcus multilocularis ecdysone induced protein 78C 0.005 0.0072 0.007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0135 0.0244 0.1068
Schistosoma mansoni ap endonuclease 0.0076 0.0125 0.027
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Mycobacterium ulcerans TetR family transcriptional regulator 0.1451 0.2905 1
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0018 0.0008 0.0034
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.0189 0.0644
Onchocerca volvulus Bile acid receptor homolog 0.005 0.0072 0.0296
Schistosoma mansoni RAR-like nuclear receptor 0.005 0.0072 0.0155
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0023 0.0302
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.1451 0.2905 1
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0019 0.0082
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.0189 0.0644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Cytochrome P450 family protein 0.0036 0.0043 0.0189
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0083 0.0139 0.03
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.0189 0.0644
Brugia malayi hypothetical protein 0.0018 0.0008 0.0034
Onchocerca volvulus 0.0024 0.0019 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Schistosoma mansoni smad 0.0026 0.0023 0.0047
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0005 0.0003
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Echinococcus granulosus survival motor neuron protein 1 0.0724 0.1435 0.3127
Mycobacterium ulcerans lipase LipD 0.0108 0.0189 0.0577
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0164 0.0353
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Onchocerca volvulus 0.0018 0.0008 0.0032
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0006 0.0012
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0019 0.0036
Echinococcus multilocularis musashi 0.0135 0.0244 0.0242
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0084
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0125 0.0511
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0023 0.0045
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0076 0.0125 0.5663
Brugia malayi Fli-1 protein 0.0235 0.0445 0.1952
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0123 0.0219 0.0217
Plasmodium vivax vivapain-2 0.0017 0.0005 0.0095
Schistosoma mansoni inositol monophosphatase 0.0043 0.0058 0.0124
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0063 0.0133
Giardia lamblia GTOR 0.0018 0.0006 0.0203
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0423 0.0827 0.0825
Echinococcus multilocularis RUN 0.002 0.0011 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0189 0.0774
Trypanosoma brucei prolyl endopeptidase 0.0083 0.0139 0.2032
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0002 0.0029
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0019 0.0036
Schistosoma mansoni lipoxygenase 0.0084 0.014 0.0303
Schistosoma mansoni hypothetical protein 0.0148 0.0269 0.0586
Onchocerca volvulus Alhambra homolog 0.0028 0.0028 0.0116
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0058 0.0238
Echinococcus multilocularis snurportin 1 0.0609 0.1203 0.1201
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0154 0.0282 0.0614
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0076 0.0125 0.0355
Echinococcus granulosus lysosomal alpha glucosidase 0.0174 0.0323 0.07
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0006 0.0094
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Trichomonas vaginalis set domain proteins, putative 0.1222 0.2442 1
Schistosoma mansoni nocturnin 0.0015 0.0002 0.0002
Brugia malayi nuclear receptor NHR-88 0.005 0.0072 0.0317
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0015 0.0002 0.0029
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0006 0.0094
Schistosoma mansoni ran 0.0042 0.0056 0.0119
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0019 0.0082
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0017 0.0006 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0023 0.0071
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0123 0.0219 0.3209
Brugia malayi prolyl oligopeptidase family protein 0.0083 0.0139 0.0607
Brugia malayi Nuclear hormone receptor family member nhr-40 0.005 0.0072 0.0317
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0123 0.0219 0.0896
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0066 0.0288
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Onchocerca volvulus 0.0162 0.0299 0.1223
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0083 0.0139 0.2032
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0129 0.0564
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0076 0.0125 0.183
Loa Loa (eye worm) prolyl oligopeptidase 0.1046 0.2085 0.9138
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0154 0.0282 0.0614
Brugia malayi Cytochrome P450 family protein 0.0104 0.0181 0.0791
Brugia malayi prolyl oligopeptidase family protein 0.1046 0.2085 0.9138
Schistosoma mansoni Smad4 0.0026 0.0023 0.0047
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0423 0.0827 0.0825
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0019 0.0017
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.004 0.0176
Brugia malayi jmjC domain containing protein 0.0034 0.004 0.0176
Schistosoma mansoni importin beta-1 0.0057 0.0086 0.0186
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0386
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0083 0.0139 0.2032
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0219 0.0896
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.0189 0.2771
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0129 0.0127
Onchocerca volvulus 0.0101 0.0174 0.0714
Brugia malayi Calcitonin receptor-like protein seb-1 0.0247 0.047 0.2058
Loa Loa (eye worm) hypothetical protein 0.0057 0.0086 0.0378
Loa Loa (eye worm) transcription factor SMAD2 0.0376 0.0732 0.3206
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0076 0.0125 0.183
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0117 0.0513
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0018 0.0008 0.0006
Schistosoma mansoni ap endonuclease 0.0076 0.0125 0.027
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0023 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0066 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Schistosoma mansoni nuclear receptor 0.0024 0.0019 0.0038
Echinococcus granulosus histone lysine methyltransferase setb 0.0154 0.0282 0.0612
Onchocerca volvulus 0.0148 0.0269 0.1104
Onchocerca volvulus 0.0017 0.0005 0.0019
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.005 0.0072 0.0317
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.0189 0.0644
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0072 0.0153
Schistosoma mansoni hypothetical protein 0.0664 0.1314 0.2865
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0423 0.0827 0.18
Giardia lamblia Alanyl dipeptidyl peptidase 0.0083 0.0139 0.6297
Schistosoma mansoni GTP-binding protein alpha subunit 0.0018 0.0008 0.0014
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0125 0.0511
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.0245
Schistosoma mansoni GTP-binding protein alpha subunit 0.0018 0.0008 0.0014
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0019 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Echinococcus multilocularis GPCR, family 2 0.0078 0.0129 0.0127
Onchocerca volvulus Prolyl endopeptidase homolog 0.0083 0.0139 0.0567
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0717
Brugia malayi MH1 domain containing protein 0.0026 0.0023 0.01
Onchocerca volvulus Protein ultraspiracle homolog 0.005 0.0072 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Schistosoma mansoni hypothetical protein 0.0045 0.0063 0.0135
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0008 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Entamoeba histolytica Ran family GTPase 0.0042 0.0056 0.1003
Echinococcus granulosus ubiquitin specific protease 41 0.0111 0.0195 0.0421
Leishmania major hypothetical protein, conserved 0.0108 0.0189 0.2771
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.002 0.0018
Leishmania major endonuclease/exonuclease protein-like protein 0.0015 0.0002 0.0029
Toxoplasma gondii prolyl endopeptidase 0.0083 0.0139 0.2008
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.0189 0.0644
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0064 0.0264
Brugia malayi prolyl oligopeptidase family protein 0.0083 0.0139 0.0607
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0023 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0049 0.0718
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0423 0.0827 0.3623
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1046 0.2085 0.2084
Onchocerca volvulus 0.0018 0.0008 0.0032
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0054 0.1868
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0006 0.001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.0189 0.0828
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0111 0.0195 0.8905
Echinococcus multilocularis protein patched 0.0041 0.0054 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.005
Onchocerca volvulus 0.002 0.0011 0.0046
Schistosoma mansoni alpha glucosidase 0.0039 0.0049 0.0104
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0111 0.0195 0.3505
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0006 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0154 0.0282 0.0614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0164 0.0717
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0019 0.0036
Schistosoma mansoni hypothetical protein 0.0026 0.0023 0.0047
Brugia malayi photoreceptor-specific nuclear receptor 0.005 0.0072 0.0317
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0018 0.0008 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Echinococcus multilocularis acylamino acid releasing enzyme 0.0083 0.0139 0.0137
Brugia malayi Intermediate filament tail domain containing protein 0.0135 0.0244 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi nuclear receptor RXR 0.0026 0.0024 0.0107
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0099 0.1458
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0075 0.1104
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.005 0.0072 0.007
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0019 0.0038
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0023 0.0071
Trypanosoma cruzi oligopeptidase b 0.0083 0.0139 0.2032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Onchocerca volvulus 0.0108 0.0189 0.0774
Brugia malayi Smad1 0.0026 0.0023 0.01
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.0189 0.0644
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0176 0.2581
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0054 0.0114
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0019 0.0017
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0018 0.0008 0.0034
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0123 0.0219 0.3209
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0423 0.0827 0.3623
Brugia malayi Nuclear hormone receptor family member nhr-31 0.005 0.0072 0.0317
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0006 0.0094
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0006 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0023 0.0071
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0176 0.2559
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0005 0.0019
Onchocerca volvulus 0.0015 0.0002 0.0008
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0006 0.0094
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0006 0.0094
Brugia malayi RNA binding protein 0.02 0.0376 0.1648
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0043 0.0634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Plasmodium vivax importin-beta 2, putative 0.0057 0.0086 0.3007
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0018 0.0008 0.0034
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0075 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0123 0.0219 0.3931
Brugia malayi Nuclear hormone receptor family member nhr-1 0.005 0.0072 0.0317
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0018 0.0008 0.0032
Schistosoma mansoni lipoxygenase 0.0119 0.0212 0.0461
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.005 0.0072 0.007
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0023 0.0071
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0083 0.0139 0.2032
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0015 0.0002 0.0036
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0056 0.0819
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0139 0.2032
Schistosoma mansoni coup transcription factor 0.005 0.0072 0.0155
Trypanosoma brucei prolyl oligopeptidase, putative 0.0083 0.0139 0.2032
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.0189 0.0408
Brugia malayi hypothetical protein 0.002 0.0011 0.005
Brugia malayi cytochrome P450 0.0026 0.0023 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0015 0.0002 0.0029
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0015 0.0002 0.0029
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0352 0.0682 1
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0018 0.0008 0.0034
Onchocerca volvulus 0.0017 0.0005 0.0019
Schistosoma mansoni inositol monophosphatase 0.0043 0.0058 0.0124
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0176 0.6206
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0043 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0352 0.0682 1
Echinococcus multilocularis peregrin 0.0032 0.0035 0.0033
Onchocerca volvulus Putative neutral sphingomyelinase 0.0015 0.0002 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0023 0.0071
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0609 0.1203 0.5269
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0255 0.0553
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0255 0.1116
Loa Loa (eye worm) prolyl oligopeptidase 0.0083 0.0139 0.0607
Loa Loa (eye worm) cytochrome P450 0.0026 0.0023 0.0099
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0018 0.0008 0.0014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0002 0.0029
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0023 0.0071
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0051 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Brugia malayi Serine carboxypeptidase S28 family protein 0.0123 0.0219 0.0959
Loa Loa (eye worm) hypothetical protein 0.0065 0.0103 0.0449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Schistosoma mansoni gabp alpha 0.0077 0.0127 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0049 0.0162
Schistosoma mansoni cript-related 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0169 0.0312 0.1366
Brugia malayi MH1 domain containing protein 0.0026 0.0023 0.01
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0018 0.0008 0.0012
Trichomonas vaginalis esterase, putative 0.0108 0.0189 0.0774
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0018 0.0008 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0111 0.0195 0.0799
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Schistosoma mansoni thyroid hormone receptor 0.005 0.0072 0.0155
Giardia lamblia Serine peptidase, putative 0.0123 0.0219 1
Echinococcus multilocularis 0.0026 0.0023 0.0021
Giardia lamblia Thymus-specific serine protease precursor 0.0123 0.0219 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0024 0.0051
Echinococcus granulosus expressed protein 0.0018 0.0008 0.0012
Schistosoma mansoni hypothetical protein 0.0664 0.1314 0.2865
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0056 0.0792
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0083 0.0139 0.0402
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0056 0.0118
Onchocerca volvulus 0.0152 0.0278 0.1137
Leishmania major cathepsin L-like protease 0.0064 0.0099 0.1458
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0212 0.021
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Leishmania major hypothetical protein, conserved 0.0101 0.0176 0.2581
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0019 0.0077
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0042 0.1419
Mycobacterium ulcerans hypothetical protein 0.0047 0.0066 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Leishmania major oligopeptidase b 0.0083 0.0139 0.2032
Brugia malayi CCR4 0.0015 0.0002 0.0009
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0129 0.0277
Loa Loa (eye worm) fibroinase 0.0017 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0041 0.0054 0.0235
Echinococcus multilocularis thyroid hormone receptor alpha 0.005 0.0072 0.007
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0029
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0019 0.0036
Echinococcus granulosus RUN 0.002 0.0011 0.002
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0018 0.0008 0.0034
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0006 0.0028
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0159 0.0342
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0043 0.0634
Onchocerca volvulus Huntingtin homolog 0.0119 0.0211 0.0865
Brugia malayi Pre-SET motif family protein 0.0154 0.0282 0.1237
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0072 0.007
Loa Loa (eye worm) cysteine protease 0.0017 0.0005 0.002
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0054 0.0235
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0111 0.0195 0.0423
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0042 0.5
Brugia malayi MH2 domain containing protein 0.0026 0.0023 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0066 0.015
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0247 0.0534
Loa Loa (eye worm) hypothetical protein 0.0119 0.0211 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0002 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0111 0.0195 0.0193
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0054 0.0113
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0049 0.0201
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0008 0.0034
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0054 0.077
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0005 0.0153
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Onchocerca volvulus 0.0123 0.0219 0.0896
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0089 0.0391
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1046 0.2085 0.854
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0125 0.438
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.002 0.0086
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0015 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0002 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0023 0.0071
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0103 0.022
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Echinococcus granulosus tumor protein p63 0.1036 0.2066 0.4506
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Brugia malayi hypothetical protein 0.0119 0.0211 0.0925
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0049 0.0691
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0059
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0066 0.015
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0099 0.1458
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0019 0.0082
Entamoeba histolytica G protein alpha subunit, putative 0.0018 0.0008 0.0138
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0018 0.0008 0.0034
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.005 0.0072 0.0155
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.005 0.0072 0.0153
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0002 0.0029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0023 0.0047
Brugia malayi intermediate filament protein 0.0135 0.0244 0.1068
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0023 0.0071
Brugia malayi MAP kinase sur-1 0.0052 0.0075 0.033
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0066 0.0288
Giardia lamblia PHD finger protein 15 0.0028 0.0028 0.1209
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0028 0.0124
Onchocerca volvulus 0.0154 0.0282 0.1156
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0124
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0352 0.0682 0.1486
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0008 0.0034
Echinococcus granulosus lamin 0.0135 0.0244 0.0528
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0049 0.0201
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0024 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi PHD-finger family protein 0.0028 0.0028 0.0124
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0129 0.0277
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0018 0.0008 0.0006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0174 0.0323 0.1413
Plasmodium falciparum importin beta, putative 0.0057 0.0086 0.4846
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0288
Echinococcus multilocularis expressed conserved protein 0.009 0.0152 0.015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0005 0.0003
Brugia malayi hypothetical protein 0.0269 0.0514 0.2253
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0212 0.0459
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0111 0.0195 0.0423
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0049 0.0103
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0028 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0005 0.0019
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0023 0.0071
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0018 0.0008 0.0014
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.0323 0.0321
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0111 0.0195 0.0421
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0023 0.0071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0083 0.0139 0.0607
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.1046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0072 0.007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0023 0.0021
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0083 0.0139 0.0567
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0176 0.2581
Echinococcus granulosus snurportin 1 0.0609 0.1203 0.2621
Loa Loa (eye worm) G protein alpha subunit 3 0.0018 0.0008 0.0034
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0167 0.0361
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.0323 0.0321
Schistosoma mansoni thyroid hormone receptor 0.005 0.0072 0.0155
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0064 0.0264
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.005 0.0072 0.0317
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0005 0.0008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0006 0.0028
Loa Loa (eye worm) RNA binding protein 0.02 0.0376 0.1648

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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