Detailed information for compound 1053803

Basic information

Technical information
  • TDR Targets ID: 1053803
  • Name: 5-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl] -N,N,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-2 -amine
  • MW: 380.487 | Formula: C21H28N6O
  • H donors: 1 H acceptors: 2 LogP: 2.92 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1N1CCN(CC1)Cc1c(C)[nH]c2c1cnc(n2)N(C)C
  • InChi: 1S/C21H28N6O/c1-15-17(16-13-22-21(25(2)3)24-20(16)23-15)14-26-9-11-27(12-10-26)18-7-5-6-8-19(18)28-4/h5-8,13H,9-12,14H2,1-4H3,(H,22,23,24)
  • InChiKey: ADAZZWTYEBRRHE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-N,N,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
  • [5-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-dimethyl-amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bos taurus Dopamine D1 receptor Starlite/ChEMBL References
Homo sapiens dopamine receptor D3 Starlite/ChEMBL References
Homo sapiens dopamine receptor D4 Starlite/ChEMBL References
Homo sapiens dopamine receptor D2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum 5-hydroxytryptamine receptor 1, putative Get druggable targets OG5_132667 All targets in OG5_132667
Schistosoma japonicum 5-hydroxytryptamine receptor, putative Get druggable targets OG5_132667 All targets in OG5_132667
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Dopamine D1 receptor   446 aa 371 aa 34.5 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Dopamine D1 receptor   446 aa 373 aa 27.1 %
Loa Loa (eye worm) hypothetical protein Dopamine D1 receptor   446 aa 370 aa 24.3 %
Onchocerca volvulus Dopamine D1 receptor   446 aa 359 aa 21.4 %
Brugia malayi hypothetical protein dopamine receptor D3 400 aa 392 aa 19.9 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Dopamine D1 receptor   446 aa 398 aa 33.9 %
Schistosoma mansoni biogenic amine (5HT) receptor Dopamine D1 receptor   446 aa 393 aa 32.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis STE family protein kinase 0.1157 0.1149 1
Echinococcus multilocularis roundabout 2 0.0868 0.0806 0.0806
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis dual specificity 0.026 0.0081 0.0081
Schistosoma mansoni serine/threonine-protein kinase 0.032 0.0153 0.0374
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0722 0.0632 0.0848
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0232 0.0048 0.0048
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Loa Loa (eye worm) hypothetical protein 0.0717 0.0625 0.084
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Echinococcus multilocularis mitogen activated protein kinase 11 0.5022 0.5749 0.5749
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.017 0.0416
Echinococcus granulosus insulin receptor 0.1264 0.1277 0.2221
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0965 0.092 0.1593
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0085 0.0097
Plasmodium vivax casein kinase 1, putative 0.0584 0.0467 0.4315
Schistosoma mansoni tyrosine kinase 0.3626 0.4087 1
Echinococcus granulosus roundabout 2 0.0868 0.0806 0.1401
Trypanosoma cruzi casein kinase, putative 0.0584 0.0467 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.0332 0.0167 0.0409
Loa Loa (eye worm) hypothetical protein 0.0531 0.0404 0.0541
Trichomonas vaginalis STE family protein kinase 0.0331 0.0166 0.1406
Trichomonas vaginalis CMGC family protein kinase 0.1095 0.1076 0.9358
Schistosoma mansoni SH2A 0.0207 0.0019 0.0047
Schistosoma mansoni tyrosine kinase 0.0582 0.0466 0.1139
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0517 0.0388 0.0388
Schistosoma mansoni serine/threonine protein kinase 0.2693 0.2978 0.7285
Loa Loa (eye worm) hypothetical protein 0.0836 0.0767 0.1031
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.0048 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Giardia lamblia Kinase, CK1 Casein kinase 0.0584 0.0467 0.3989
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0211 0.0023 0.0027
Brugia malayi serine/threonine-protein kinase 6 0.056 0.0439 0.0576
Entamoeba histolytica protein kinase domain containing protein 0.0221 0.0035 0.0325
Schistosoma mansoni protein kinase 0.0331 0.0166 0.0407
Echinococcus granulosus serine/threonine protein kinase 0.032 0.0153 0.0266
Schistosoma mansoni tensin 0.0207 0.0019 0.0047
Echinococcus granulosus tyrosine protein kinase csk 0.0232 0.0048 0.0084
Schistosoma mansoni signal transduction protein lnk-related 0.0207 0.0019 0.0047
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0262 0.0085 0.0088
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0323 0.0157 0.0274
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0277 0.0102 0.0906
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1095 0.1076 0.1448
Schistosoma mansoni myosin-binding protein-related 0.0211 0.0023 0.0057
Echinococcus multilocularis tyrosine kinase 0.0232 0.0048 0.0048
Echinococcus multilocularis casein kinase I delta 0.0584 0.0467 0.0467
Entamoeba histolytica SH2 domain containing protein 0.0207 0.0019 0.018
Loa Loa (eye worm) hypothetical protein 0.0257 0.0078 0.01
Brugia malayi Immunoglobulin I-set domain containing protein 0.3216 0.36 0.4852
Schistosoma mansoni nck2/grb4 0.0372 0.0215 0.0527
Loa Loa (eye worm) hypothetical protein 0.0231 0.0047 0.0059
Echinococcus granulosus contactin 0.0295 0.0123 0.0214
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0932 0.0882 0.1187
Loa Loa (eye worm) projectin 0.0211 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0636 0.053 0.0711
Plasmodium falciparum serine/threonine protein kinase 0.0203 0.0015 0.0086
Trichomonas vaginalis TK family protein kinase 0.0232 0.0048 0.0373
Giardia lamblia Kinase, NEK 0.0257 0.0078 0.0558
Loa Loa (eye worm) AGC/PKN protein kinase 0.1579 0.1652 0.2227
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Echinococcus multilocularis natriuretic peptide receptor 1 0.0232 0.0048 0.0048
Schistosoma mansoni tyrosine kinase 0.1951 0.2095 0.5125
Echinococcus granulosus calcium dependent protein kinase 0.0364 0.0206 0.0357
Echinococcus multilocularis serine:threonine protein kinase 0.0319 0.0152 0.0152
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0329 0.0164 0.0275
Echinococcus granulosus c-Jun N-terminal kinases 0.278 0.308 0.5358
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis tumor protein p63 0.033 0.0165 0.0165
Loa Loa (eye worm) TK/CSK protein kinase 0.0232 0.0048 0.006
Loa Loa (eye worm) hypothetical protein 0.0636 0.053 0.0711
Plasmodium falciparum protein kinase 5 0.042 0.0273 0.2497
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0329 0.0164 0.0164
Echinococcus granulosus casein kinase I delta 0.0584 0.0467 0.0813
Brugia malayi hypothetical protein 0.0231 0.0047 0.0046
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Entamoeba histolytica protein kinase, putative 0.0361 0.0202 0.1875
Loa Loa (eye worm) hypothetical protein 0.0439 0.0295 0.0394
Plasmodium falciparum casein kinase 2, alpha subunit 0.0221 0.0035 0.0276
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0232 0.0048 0.0048
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.217 0.2355 0.3177
Trypanosoma brucei cdc2-related kinase 1 0.042 0.0273 0.0465
Entamoeba histolytica protein kinase domain containing protein 0.0323 0.0157 0.1462
Echinococcus granulosus protein kinase 0.0896 0.0839 0.1459
Loa Loa (eye worm) hypothetical protein 0.0267 0.009 0.0117
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0584 0.0467 0.0626
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Schistosoma mansoni vesicular amine transporter 0.0573 0.0455 0.1113
Onchocerca volvulus 0.0439 0.0295 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0013 0.0064
Leishmania major protein kinase A catalytic subunit 0.0691 0.0595 0.1026
Brugia malayi Prion-like- 0.0262 0.0085 0.0097
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.056 0.0439 0.0439
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0636 0.053 0.0922
Loa Loa (eye worm) hypothetical protein 0.1379 0.1413 0.1905
Brugia malayi cytokine inducible SH2-containing protein 5 0.0207 0.0019 0.0009
Echinococcus multilocularis myosin iiia 0.0205 0.0016 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0553 0.0431 0.3718
Echinococcus multilocularis 0.0896 0.0839 0.0839
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Loa Loa (eye worm) hypothetical protein 0.0262 0.0085 0.011
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1025 0.0992 0.0992
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0236 0.0053 0.0092
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0538 0.0413 0.0718
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.0048 0.006
Entamoeba histolytica protein kinase 2, putative 0.0277 0.0102 0.0952
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0323 0.0157 0.0208
Schistosoma mansoni protein kinase 0.056 0.0439 0.1073
Trichomonas vaginalis STE family protein kinase 0.0257 0.0078 0.0634
Schistosoma mansoni protein kinase 0.0221 0.0035 0.0085
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1359 0.139 0.139
Echinococcus multilocularis protein kinase c epsilon type 0.0656 0.0553 0.0553
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1025 0.0992 0.0992
Schistosoma mansoni serine/threonine protein kinase 0.0629 0.0522 0.1276
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1885 0.2016 0.3507
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0616 0.0506 0.0879
Trichomonas vaginalis STE family protein kinase 0.1157 0.1149 1
Schistosoma mansoni protein kinase 0.234 0.2557 0.6257
Schistosoma mansoni serine/threonine protein kinase 0.0696 0.0601 0.147
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0232 0.0048 0.0048
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1025 0.0992 0.0992
Entamoeba histolytica protein kinase, putative 0.0653 0.0549 0.5109
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0211 0.0023 0.0027
Echinococcus multilocularis hemicentin 1 0.0262 0.0085 0.0085
Echinococcus granulosus suppressor of cytokine signaling 7 0.0207 0.0019 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Onchocerca volvulus 0.0232 0.0048 0.0039
Echinococcus multilocularis serine:threonine protein kinase N2 0.1069 0.1044 0.1044
Entamoeba histolytica hypothetical protein 0.0234 0.0051 0.0478
Echinococcus multilocularis mitogen activated protein kinase 14 0.5022 0.5749 0.5749
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0232 0.0048 0.0398
Echinococcus multilocularis cyclin dependent kinase 19 0.1647 0.1733 0.1733
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0353 0.0192 0.0192
Giardia lamblia Kinase, STE STE20 0.0353 0.0192 0.1565
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0255 0.0076 0.0076
Plasmodium falciparum serine/threonine protein kinase KIN 0.0329 0.0164 0.1478
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1293 0.1312 0.1312
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0205 0.0016 0.0019
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0262 0.0085 0.011
Echinococcus multilocularis mitogen activated protein kinase 0.0204 0.0015 0.0015
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0232 0.0048 0.0398
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0232 0.0048 0.006
Schistosoma mansoni septate junction protein 0.0262 0.0085 0.0207
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0232 0.0048 0.006
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0329 0.0164 0.0275
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0285 0.0111 0.0194
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Toxoplasma gondii STE kinase 0.0232 0.0048 0.0398
Loa Loa (eye worm) hypothetical protein 0.0372 0.0215 0.0286
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.041 0.026 0.0453
Schistosoma mansoni tyrosine kinase 0.0653 0.055 0.1345
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0484 0.0349 0.0349
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Echinococcus multilocularis activated cdc42 kinase 1 0.161 0.1689 0.1689
Echinococcus multilocularis rac serine:threonine kinase 0.032 0.0153 0.0153
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0983 0.0942 0.1638
Echinococcus multilocularis roundabout 2 0.0295 0.0123 0.0123
Toxoplasma gondii AGC kinase 0.0634 0.0528 0.4879
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0517 0.0388 0.0675
Echinococcus multilocularis calcium dependent protein kinase 0.0364 0.0206 0.0206
Schistosoma mansoni adapter molecule crk 0.0372 0.0215 0.0527
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Loa Loa (eye worm) hypothetical protein 0.0636 0.053 0.0711
Schistosoma mansoni atypical protein kinase C 0.0744 0.0658 0.161
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0636 0.053 0.0913
Schistosoma mansoni hypothetical protein 0.0636 0.053 0.1296
Schistosoma mansoni tensin-related 0.0207 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.032 0.0153 0.0202
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0401 0.025 0.0333
Loa Loa (eye worm) hypothetical protein 0.0199 0.001 0.0008
Onchocerca volvulus 0.0232 0.0048 0.0039
Plasmodium falciparum protein kinase, putative 0.0232 0.0048 0.0398
Echinococcus granulosus SHC transforming protein 3 0.0207 0.0019 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus granulosus aurora kinase A 0.056 0.0439 0.0763
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0013 0.0064
Echinococcus granulosus cyclin dependent kinase 7 0.0629 0.0522 0.0907
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.0048 0.006
Brugia malayi intracellular kinase 0.1095 0.1076 0.1438
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Echinococcus granulosus defective proboscis extension response 0.0573 0.0455 0.0791
Echinococcus granulosus tyrosine protein kinase HCK 0.0653 0.0549 0.0956
Brugia malayi Receptor family ligand binding region containing protein 0.0232 0.0048 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.032 0.0153 0.0202
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0207 0.0019 0.0019
Entamoeba histolytica protein kinase, putative 0.0234 0.0051 0.0478
Brugia malayi SRC-1 0.1025 0.0992 0.1325
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0232 0.0048 0.0048
Schistosoma mansoni tyrosine kinase 0.0409 0.0259 0.0635
Trypanosoma cruzi polo-like protein kinase, putative 0.0296 0.0125 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0157 0.0385
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Schistosoma mansoni serine/threonine protein kinase 0.1647 0.1733 0.4239
Schistosoma mansoni tyrosine kinase 0.0494 0.036 0.0881
Echinococcus multilocularis transfer RNA-Thr 0.161 0.1689 0.1689
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0207 0.0019 0.0019
Echinococcus multilocularis 0.0217 0.003 0.003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Brugia malayi serine/threonine-protein kinase plk-2 0.0296 0.0125 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Loa Loa (eye worm) STAT protein 0.0207 0.0019 0.0021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0644 0.0539 0.0539
Loa Loa (eye worm) TK/Met protein kinase 0.0232 0.0048 0.006
Echinococcus granulosus serine:threonine protein kinase 0.0319 0.0152 0.0264
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2159 0.2342 0.2342
Echinococcus granulosus activated cdc42 kinase 1 0.161 0.1689 0.2937
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Brugia malayi Protein kinase domain containing protein 0.0722 0.0632 0.0837
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Giardia lamblia Kinase, CMGC MAPK 0.0204 0.0015 0.0007
Echinococcus granulosus tyrosine kinase 0.0232 0.0048 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0983 0.0942 0.2305
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0123 0.015
Echinococcus multilocularis cyclin dependent kinase 7 0.0629 0.0522 0.0522
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0285 0.0111 0.0111
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Echinococcus granulosus cGMP dependent protein kinase 1 0.0255 0.0076 0.0132
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0204 0.0015 0.0017
Plasmodium vivax tyrosine kinase-like protein, putative 0.0232 0.0048 0.0398
Plasmodium falciparum tyrosine kinase-like protein 0.0232 0.0048 0.0398
Schistosoma mansoni tyrosine kinase 0.0814 0.0741 0.1813
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0965 0.092 0.1593
Brugia malayi Casein kinase II, alpha chain 0.0221 0.0035 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0085 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.0206 0.0503
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0081 0.0664
Loa Loa (eye worm) hypothetical protein 0.025 0.007 0.009
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.217 0.2355 0.2355
Brugia malayi Protein kinase domain containing protein 0.0439 0.0295 0.0382
Echinococcus multilocularis integrin linked protein kinase 0.0232 0.0048 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.1537 0.1602 0.215
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0262 0.0085 0.0085
Leishmania major protein kinase, putative 0.0232 0.0048 0.0074
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1014 0.098 0.1308
Echinococcus multilocularis protein kinase c iota type 0.0738 0.0651 0.0651
Schistosoma mansoni serine/threonine protein kinase 0.278 0.308 0.7536
Schistosoma mansoni tyrosine kinase 0.1025 0.0992 0.2428
Schistosoma mansoni septate junction protein 0.0262 0.0085 0.0207
Loa Loa (eye worm) hypothetical protein 0.0319 0.0152 0.02
Trypanosoma cruzi protein kinase, putative 0.0232 0.0048 0.0074
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0584 0.0467 0.0626
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0257 0.0078 0.0678
Schistosoma mansoni protein kinase 0.0896 0.0839 0.2051
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Echinococcus multilocularis cyclin dependent kinase 1 0.042 0.0273 0.0273
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.026 0.0081 0.0105
Loa Loa (eye worm) hypothetical protein 0.0265 0.0088 0.0114
Plasmodium falciparum tyrosine kinase-like protein 0.0232 0.0048 0.0398
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0538 0.0413 0.0413
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0936 0.0886 0.1182
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1379 0.1414 0.2459
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0352 0.0191 0.0191
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0965 0.092 0.8551
Trypanosoma brucei rac serine-threonine kinase, putative 0.0677 0.0578 0.0997
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Loa Loa (eye worm) hypothetical protein 0.0262 0.0085 0.011
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0329 0.0164 0.0216
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi ephrin receptor 1 precursor 0.0262 0.0084 0.0097
Plasmodium vivax protein kinase, putative 0.0247 0.0066 0.0567
Echinococcus granulosus cGMP dependent protein kinase 1 0.0255 0.0076 0.0132
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Echinococcus granulosus roundabout 2 0.0295 0.0123 0.0214
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Echinococcus multilocularis cyclin dependent kinase 9 0.0372 0.0215 0.0215
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis SH2 motif 0.0207 0.0019 0.0019
Schistosoma mansoni rap gtpase-activating protein 0.0636 0.053 0.1296
Brugia malayi C1-like domain containing protein 0.1014 0.098 0.1308
Schistosoma mansoni tyrosine kinase 0.0762 0.068 0.1663
Schistosoma mansoni tyrosine kinase 0.1025 0.0992 0.2428
Echinococcus multilocularis tyrosine protein kinase 0.0232 0.0048 0.0048
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni cell adhesion molecule 0.0262 0.0085 0.0207
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0232 0.0048 0.0118
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0573 0.0455 0.0455
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0203 0.0015 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0081 0.0664
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0691 0.0595 0.1026
Giardia lamblia Kinase, STE STE20 0.1157 0.1149 1
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Brugia malayi Egg laying defective protein 4 0.0255 0.0076 0.0086
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) hypothetical protein 0.0811 0.0738 0.0993
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2128 0.2305 0.3101
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0517 0.0388 0.0388
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Brugia malayi Cam kinase protein 1 0.0517 0.0388 0.0507
Loa Loa (eye worm) TK/EGFR protein kinase 0.0953 0.0907 0.122
Plasmodium vivax tyrosine kinase-like protein, putative 0.0201 0.0012 0.0063
Brugia malayi Protein kinase domain containing protein 0.3666 0.4135 0.5577
Loa Loa (eye worm) AUR protein kinase 0.056 0.0439 0.0588
Echinococcus granulosus nephrin 0.0211 0.0023 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Onchocerca volvulus 0.0904 0.0848 0.1122
Brugia malayi cyclin-dependent kinase 9 0.034 0.0177 0.0222
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0085 0.0097
Brugia malayi Guanylyl cyclase protein 23 0.0232 0.0048 0.0048
Brugia malayi Protein kinase domain containing protein 0.0439 0.0295 0.0382
Echinococcus multilocularis lachesin 0.0262 0.0085 0.0085
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1074 0.105 0.1414
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0431 0.0285 0.0486
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0204 0.0015 0.0017
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0207 0.0019 0.0019
Toxoplasma gondii AGC kinase 0.0691 0.0595 0.5508
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0207 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0515 0.0386 0.0944
Brugia malayi Protein kinase domain containing protein 0.051 0.038 0.0497
Entamoeba histolytica protein kinase, putative 0.026 0.0081 0.0756
Schistosoma mansoni serine/threonine protein kinase 0.0584 0.0467 0.1143
Plasmodium falciparum casein kinase 1 0.0584 0.0467 0.4315
Echinococcus granulosus cGMP dependent protein kinase 0.0255 0.0076 0.0132
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0257 0.0078 0.0678
Echinococcus granulosus fibroblast growth factor receptor 4 0.1359 0.139 0.2418
Onchocerca volvulus Serine\/threonine kinase homolog 0.0285 0.0111 0.0124
Schistosoma mansoni tensin 0.0207 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Giardia lamblia Kinase, CMGC CDK 0.042 0.0273 0.2274
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0743 0.0657 0.0657
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1025 0.0992 0.1726
Loa Loa (eye worm) hypothetical protein 0.0606 0.0493 0.0662
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0979 0.0937 0.1622
Brugia malayi Peroxidasin 0.0265 0.0088 0.0102
Echinococcus multilocularis casein kinase I gamma 0.0334 0.017 0.017
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Brugia malayi Protein kinase domain containing protein 0.161 0.1689 0.2267
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0517 0.0388 0.0388
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.042 0.0273 0.2497
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0081 0.0664
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1074 0.105 0.1819
Loa Loa (eye worm) TK protein kinase 0.0232 0.0048 0.006
Onchocerca volvulus 0.0712 0.062 0.0814
Trypanosoma cruzi cdc2-related kinase 1 0.042 0.0273 0.0465
Schistosoma mansoni tyrosine protein kinase 0.0232 0.0048 0.0118
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.203 0.2188 0.2952
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0932 0.0882 0.0882
Brugia malayi Protein kinase domain containing protein 0.0747 0.0661 0.0878
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.056 0.0439 0.4078
Brugia malayi hypothetical protein 0.0207 0.0019 0.0009
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0203 0.0015 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Echinococcus granulosus dual specificity mitogen activated protein 0.1157 0.1149 0.1998
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0385 0.023 0.0392
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0353 0.0192 0.0192
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.0048 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Trichomonas vaginalis STE family protein kinase 0.0353 0.0192 0.1633
Echinococcus multilocularis aurora kinase A 0.056 0.0439 0.0439
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0232 0.0048 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Trypanosoma cruzi protein kinase, putative 0.0232 0.0048 0.0074
Plasmodium vivax protein kinase Crk2 0.042 0.0273 0.2497
Echinococcus granulosus activated cdc42 kinase 1 0.161 0.1689 0.2937
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.026 0.0081 0.0132
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0762 0.068 0.1182
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi hypothetical protein 0.2693 0.2978 0.4011
Echinococcus multilocularis heat shock protein 70 0.0232 0.0048 0.0048
Brugia malayi p70 ribosomal S6 kinase beta 0.0634 0.0528 0.0696
Trichomonas vaginalis AGC family protein kinase 0.056 0.0439 0.3788
Echinococcus granulosus mitogen activated protein kinase 14 0.5022 0.5749 1
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Leishmania major casein kinase, putative 0.0584 0.0467 0.0804
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2253 0.2454 0.2454
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2128 0.2305 0.4009
Entamoeba histolytica protein kinase, putative 0.1074 0.105 0.9763
Brugia malayi probable protein kinase 0.1532 0.1596 0.2142
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.161 0.1689 0.2277
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Plasmodium falciparum protein serine/threonine kinase-1 0.0965 0.092 0.8551
Entamoeba histolytica cysteine surface protein, putative 0.0232 0.0048 0.0447
Schistosoma mansoni protein kinase 0.0313 0.0146 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0114 0.0279
Trichomonas vaginalis CMGC family protein kinase 0.1095 0.1076 0.9358
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2128 0.2305 0.3109
Giardia lamblia Aurora kinase 0.056 0.0439 0.3738
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0965 0.092 0.1593
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Echinococcus multilocularis ephrin type A receptor 4 A 0.0296 0.0124 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Onchocerca volvulus 0.6413 0.7405 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0321 0.0155 0.0205
Entamoeba histolytica hypothetical protein 0.0207 0.0019 0.0178
Schistosoma mansoni ste20-related kinase 0.0326 0.016 0.0392
Entamoeba histolytica protein kinase domain containing protein 0.034 0.0177 0.1642
Entamoeba histolytica protein kinase, putative 0.0203 0.0015 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Brugia malayi hypothetical protein 0.032 0.0153 0.019
Brugia malayi Fibronectin type III domain containing protein 0.0606 0.0493 0.065
Loa Loa (eye worm) CAMK protein kinase 0.0364 0.0206 0.0273
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica hypothetical protein 0.0196 0.0005 0.005
Brugia malayi SH2 domain containing protein 0.0743 0.0657 0.0872
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0255 0.0076 0.066
Loa Loa (eye worm) TK protein kinase 0.0232 0.0048 0.006
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica tyrosin kinase, putative 0.0232 0.0048 0.0447
Giardia lamblia Kinase, NEK 0.0257 0.0078 0.0558
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Trichomonas vaginalis conserved hypothetical protein 0.0199 0.001 0.0038
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1359 0.139 0.2418
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0636 0.053 0.0913
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0125 0.1046
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Echinococcus multilocularis cyclin dependent kinase 1 0.042 0.0273 0.0273
Schistosoma mansoni protein kinase 0.0584 0.0467 0.1143
Onchocerca volvulus 0.0431 0.0285 0.0359
Echinococcus multilocularis slit 2 protein 0.0257 0.0078 0.0078
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1095 0.1076 0.1863
Trypanosoma brucei Pseudokinase, putative 0.0232 0.0048 0.0074
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0207 0.0019 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1025 0.0992 0.0992
Brugia malayi Furin-like cysteine rich region family protein 0.0953 0.0907 0.121
Onchocerca volvulus 0.0439 0.0295 0.0373
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0232 0.0048 0.0048
Toxoplasma gondii CMGC kinase, CK2 family 0.0221 0.0035 0.0276
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0401 0.025 0.0434
Loa Loa (eye worm) hypothetical protein 0.0573 0.0455 0.061
Trichomonas vaginalis STE family protein kinase 0.0232 0.0048 0.0373
Brugia malayi serine/threonine kinase 12 0.056 0.0439 0.0576
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0484 0.0349 0.0606
Brugia malayi Protein kinase domain containing protein 0.0203 0.0015 0.0003
Brugia malayi protein unc-22 0.0364 0.0206 0.0261
Entamoeba histolytica cell division protein kinase 2, putative 0.0453 0.0311 0.2896
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1074 0.105 0.1819
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.026 0.0081 0.0132
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0207 0.0019 0.0021
Onchocerca volvulus 0.2327 0.2542 0.3415
Plasmodium falciparum calcium-dependent protein kinase 1 0.0517 0.0388 0.3574
Trypanosoma brucei aurora B kinase 0.056 0.0439 0.0754
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0696 0.0601 0.0601
Loa Loa (eye worm) TK protein kinase 0.1537 0.1602 0.216
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis cyclin dependent kinase 9 0.034 0.0177 0.0177
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0573 0.0455 0.1113
Echinococcus granulosus tyrosine protein kinase Src64B 0.1025 0.0992 0.1726
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.034 0.0177 0.0234
Giardia lamblia Kinase, CMGC GSK 0.1095 0.1076 0.9353
Echinococcus multilocularis cyclin dependent kinase 5 0.042 0.0273 0.0273
Schistosoma mansoni tyrosine kinase 0.1264 0.1277 0.3123
Echinococcus granulosus integrin linked protein kinase 0.0232 0.0048 0.0084
Trypanosoma brucei Casein kinase II 0.0221 0.0035 0.0051
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0352 0.0191 0.0468
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1492 0.1548 0.2076
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0203 0.0015 0.0016
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0515 0.0386 0.0517
Toxoplasma gondii casein kinase I 0.0584 0.0467 0.4315
Echinococcus multilocularis tensin 0.0207 0.0019 0.0019
Schistosoma mansoni tyrosine kinase 0.0604 0.0491 0.1201
Trypanosoma cruzi polo-like protein kinase, putative 0.0296 0.0125 0.0208
Brugia malayi protein C17H12.11 0.0574 0.0455 0.0599
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.034 0.0177 0.0432
Schistosoma mansoni serine/threonine protein kinase 0.0691 0.0595 0.1455
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0727 0.0637 0.0856
Trypanosoma brucei protein kinase, putative 0.0385 0.023 0.0392
Loa Loa (eye worm) TK/EPH protein kinase 0.0313 0.0145 0.0192
Loa Loa (eye worm) hypothetical protein 0.0574 0.0455 0.061
Leishmania major protein kinase, putative 0.056 0.0439 0.0754
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.051 0.038 0.038
Leishmania major protein kinase A catalytic subunit isoform 2 0.0691 0.0595 0.1026
Schistosoma mansoni suppressor of cytokine signaling 0.0207 0.0019 0.0047
Entamoeba histolytica protein kinase, putative 0.051 0.038 0.3533
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0277 0.0102 0.0906
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni kinase 0.034 0.0177 0.0432
Plasmodium falciparum calcium-dependent protein kinase 3 0.0517 0.0388 0.3574
Loa Loa (eye worm) hypothetical protein 0.0576 0.0458 0.0614
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0204 0.0015 0.0093
Echinococcus multilocularis epidermal growth factor receptor 0.0953 0.0907 0.0907
Entamoeba histolytica hypothetical protein 0.1074 0.105 0.9763
Schistosoma mansoni growth factor receptor-bound protein 0.0387 0.0234 0.0571
Trichomonas vaginalis AGC family protein kinase 0.0691 0.0595 0.5155
Schistosoma mansoni ephrin receptor 0.0296 0.0124 0.0304
Loa Loa (eye worm) hypothetical protein 0.032 0.0153 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0517 0.0388 0.3574
Loa Loa (eye worm) TK/ALK protein kinase 0.4635 0.5288 0.714
Brugia malayi Protein kinase domain containing protein 0.0439 0.0295 0.0382
Echinococcus granulosus suppressor of cytokine signaling 6 0.0207 0.0019 0.0034
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0517 0.0388 0.0519
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.0048 0.0048
Trypanosoma cruzi cdc2-related kinase 3 0.042 0.0273 0.0465
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0349 0.0853
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1025 0.0992 0.0992
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0081 0.0664
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0207 0.0019 0.0047
Plasmodium falciparum calcium-dependent protein kinase 4 0.0517 0.0388 0.3574
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0439 0.0295 0.2742
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0164 0.04
Echinococcus granulosus retinal guanylyl cyclase 2 0.0232 0.0048 0.0084
Giardia lamblia Kinase, CMGC GSK 0.1095 0.1076 0.9353
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0123 0.015
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.0047 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0125 0.0306
Echinococcus multilocularis expressed protein 0.0203 0.0015 0.0015
Trichomonas vaginalis AGC family protein kinase 0.056 0.0439 0.3788
Entamoeba histolytica protein kinase domain containing protein 0.056 0.0439 0.4078
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0207 0.0019 0.0034
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0251 0.0072 0.0092
Trypanosoma cruzi casein kinase, putative 0.0584 0.0467 0.0804
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0287 0.0114 0.0149
Entamoeba histolytica protein kinase, putative 0.0373 0.0217 0.2016
Echinococcus multilocularis tensin 0.0207 0.0019 0.0019
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.086 0.0796 0.1385
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi Protein kinase domain containing protein 0.0727 0.0637 0.0845
Loa Loa (eye worm) hypothetical protein 0.0857 0.0792 0.1066
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.041 0.026 0.026
Echinococcus granulosus tensin 0.0207 0.0019 0.0034
Loa Loa (eye worm) hypothetical protein 0.0262 0.0085 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.0053 0.0414
Plasmodium vivax tyrosine kinase-like protein, putative 0.0232 0.0048 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Entamoeba histolytica casein kinase 1, putative 0.0584 0.0467 0.4343
Giardia lamblia Kinase, PLK 0.0296 0.0125 0.0973
Loa Loa (eye worm) hypothetical protein 0.0262 0.0085 0.011
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0319 0.0152 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni GTPase activating protein 0.0207 0.0019 0.0047
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0372 0.0215 0.0286
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0329 0.0164 0.0275
Entamoeba histolytica cell division protein kinase 2, putative 0.042 0.0273 0.2534
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0277 0.0102 0.0169
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus granulosus cyclin dependent kinase 9 0.0372 0.0215 0.0375
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis casein kinase I alpha 0.0584 0.0467 0.0467
Brugia malayi Protein kinase domain containing protein 0.0321 0.0155 0.0193
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis STE family protein kinase 0.1157 0.1149 1
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Onchocerca volvulus 0.0232 0.0048 0.0039
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0361 0.0202 0.1875
Trichomonas vaginalis CK1 family protein kinase 0.0584 0.0467 0.4038
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1157 0.1149 0.1991
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Entamoeba histolytica protein kinase domain containing protein 0.1095 0.1076 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0204 0.0015 0.0027
Leishmania major protein kinase, putative 0.0517 0.0388 0.0666
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.026 0.0081 0.0132
Echinococcus granulosus serine:threonine protein kinase 0.0319 0.0152 0.0264
Onchocerca volvulus 0.1095 0.1076 0.143
Echinococcus multilocularis tyrosine protein kinase pr2 0.0232 0.0048 0.0048
Onchocerca volvulus 0.0636 0.053 0.0691
Brugia malayi cyclin-dependent kinase 7 homolog 0.0662 0.0561 0.0741
Echinococcus multilocularis Immunoglobulin 0.0573 0.0455 0.0455
Echinococcus multilocularis tyrosine protein kinase Fyn 0.086 0.0796 0.0796
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1025 0.0992 0.0992
Echinococcus granulosus c src tyrosine kinase 0.0604 0.0491 0.0854
Schistosoma mansoni titin 0.0262 0.0085 0.0207
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0152 0.0371
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0691 0.0595 0.1026
Brugia malayi Protein kinase domain containing protein 0.0677 0.0578 0.0765
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0265 0.0088 0.0154
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0629 0.0522 0.1276
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Echinococcus multilocularis tyrosine protein kinase Abl 0.1261 0.1273 0.1273
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0904 0.0848 0.1141
Echinococcus granulosus serine:threonine protein kinase N2 0.1579 0.1652 0.2873
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Brugia malayi casein kinase I 0.0584 0.0467 0.0615
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1358 0.1388 0.1388
Schistosoma mansoni protein kinase 0.234 0.2557 0.6257
Echinococcus granulosus NDR protein kinase 0.051 0.038 0.0661
Schistosoma mansoni serine/threonine protein kinase 0.0691 0.0595 0.1455
Trypanosoma brucei SNF1-related protein kinases, putative 0.0329 0.0164 0.0275
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Echinococcus granulosus tyrosine protein kinase csk 0.0232 0.0048 0.0084
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0202 0.0013 0.0013
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0232 0.0048 0.0373
Brugia malayi protein-tyrosine kinase 0.086 0.0796 0.106
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1157 0.1149 0.1547
Echinococcus granulosus titin 0.0364 0.0206 0.0358
Schistosoma mansoni vam6/vps39 related 0.0636 0.053 0.1296
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0023 0.0014
Brugia malayi Tensin 0.0207 0.0019 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0023 0.0014
Loa Loa (eye worm) hypothetical protein 0.0904 0.0848 0.1141
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.042 0.0273 0.0667
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0313 0.0146 0.0192
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0385 0.023 0.0392
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0296 0.0125 0.0164
Brugia malayi Protein kinase domain containing protein 0.6413 0.7405 1
Schistosoma mansoni neuroglian 0.0295 0.0123 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0965 0.092 0.2252
Echinococcus granulosus retinal guanylyl cyclase 2 0.0232 0.0048 0.0084
Onchocerca volvulus 0.0232 0.0048 0.0039
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0285 0.0111 0.0145
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0484 0.0349 0.0606
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0691 0.0595 0.1026
Entamoeba histolytica tyrosin kinase, putative 0.0273 0.0097 0.0903
Entamoeba histolytica serine/threonine protein kinase, putative 0.0329 0.0164 0.1521
Echinococcus granulosus dual specificity protein kinase clk2 0.0965 0.092 0.1601
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0023 0.0014
Giardia lamblia Kinase, AGC PKA 0.0277 0.0102 0.0774
Loa Loa (eye worm) TK protein kinase 0.0232 0.0048 0.006
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0232 0.0048 0.0118
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3216 0.36 0.4859
Schistosoma mansoni protein kinase 0.0385 0.023 0.0564
Brugia malayi hypothetical protein 0.0439 0.0295 0.0382
Entamoeba histolytica protein kinase, putative 0.056 0.0439 0.4078
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1095 0.1076 0.1863
Echinococcus granulosus cyclin dependent kinase 5 0.042 0.0273 0.0474
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2128 0.2305 0.3095
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.234 0.2557 0.4448
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1885 0.2016 0.2016
Echinococcus granulosus growth factor receptor bound protein 2 0.0387 0.0234 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.1492 0.1548 0.3786
Echinococcus granulosus tyrosine protein kinase Blk 0.086 0.0796 0.1385
Brugia malayi Protein kinase domain containing protein 0.0319 0.0152 0.0188
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Onchocerca volvulus 0.0254 0.0074 0.0075
Entamoeba histolytica protein kinase, putative 0.0373 0.0217 0.2016
Echinococcus multilocularis TGF beta receptor type 1 0.0826 0.0755 0.0755
Echinococcus granulosus tyrosine protein kinase otk 0.0262 0.0085 0.0147
Loa Loa (eye worm) AGC/PKA protein kinase 0.0691 0.0595 0.0799
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0517 0.0388 0.3574
Echinococcus granulosus tyrosine protein kinase Srms 0.0848 0.0782 0.1359
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0352 0.0191 0.0254
Brugia malayi Protein kinase domain containing protein 0.203 0.2188 0.2943
Echinococcus multilocularis neuroglian 0.0752 0.0667 0.0667
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.1035
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.0295 0.0123 0.0162
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0515 0.0386 0.0386
Brugia malayi putative serine/threonine kinase SADA gamma 0.0329 0.0164 0.0204
Brugia malayi hypothetical protein 0.0636 0.053 0.07
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis c Jun NH2 terminal kinase 0.278 0.308 0.308
Entamoeba histolytica PH domain containing protein kinase, putative 0.0196 0.0005 0.005
Echinococcus multilocularis mitogen activated protein kinase 11 0.5022 0.5749 0.5749
Schistosoma mansoni serine/threonine protein kinase 0.0574 0.0455 0.1114
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0323 0.0157 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0081 0.0199
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1359 0.139 0.139
Entamoeba histolytica hypothetical protein 0.0381 0.0226 0.2102
Echinococcus multilocularis tyrosine protein kinase Blk 0.086 0.0796 0.0796
Echinococcus multilocularis tyrosine protein kinase otk 0.0262 0.0085 0.0085
Brugia malayi Tyrosine-protein kinase abl-1 0.1261 0.1273 0.1706
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1157 0.1149 0.1537
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0385 0.023 0.023
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0629 0.0522 0.07
Brugia malayi Protein kinase domain containing protein 0.0965 0.092 0.1228
Giardia lamblia Kinase, CMGC CLK 0.0965 0.092 0.7986
Echinococcus granulosus lachesin 0.0262 0.0085 0.0147
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0232 0.0048 0.0048
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1095 0.1076 0.1076
Schistosoma mansoni serine/threonine protein kinase 0.1534 0.1598 0.3909
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0636 0.053 0.053
Brugia malayi P38 map kinase family protein 2 0.5022 0.5749 0.776
Echinococcus granulosus cyclin dependent kinase 0.042 0.0273 0.0474
Echinococcus granulosus hemicentin 1 0.0262 0.0085 0.0147
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1095 0.1076 0.1448
Echinococcus granulosus tyrosine kinase 0.0439 0.0295 0.0513
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0932 0.0882 0.1535
Toxoplasma gondii AGC kinase 0.0691 0.0595 0.5508
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0965 0.092 0.1239
Leishmania major protein kinase A catalytic subunit isoform 1 0.0691 0.0595 0.1026
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0125 0.1046
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.042 0.0273 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Echinococcus granulosus mitogen activated protein kinase 0.0204 0.0015 0.0027
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0205 0.0016 0.0019
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0634 0.0528 0.0708
Loa Loa (eye worm) hypothetical protein 0.0517 0.0388 0.0519
Brugia malayi Stress-activated protein kinase jnk-1 0.278 0.308 0.415
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.042 0.0273 0.0465
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Trypanosoma cruzi casein kinase, putative 0.0584 0.0467 0.0804
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0515 0.0386 0.0671
Onchocerca volvulus 0.0439 0.0295 0.0373
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0205 0.0016 0.0019
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Echinococcus granulosus cyclin dependent kinase 19 0.1647 0.1733 0.3014
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.0595
Echinococcus multilocularis protein KINase family member (kin 25) 0.0762 0.068 0.068
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0232 0.0048 0.0084
Schistosoma mansoni tyrosine kinase 0.2104 0.2276 0.5568
Plasmodium vivax serine/threonine protein kinase 6, putative 0.056 0.0439 0.4048
Loa Loa (eye worm) SH2 domain-containing protein 0.0207 0.0019 0.0021
Echinococcus granulosus SH2 motif 0.0207 0.0019 0.0034
Brugia malayi integrin-linked kinase 0.0232 0.0048 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0023 0.0014
Echinococcus granulosus casein kinase ii subunit alpha 0.0221 0.0035 0.0061
Echinococcus granulosus tyrosine protein kinase csk 0.0232 0.0048 0.0084
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0372 0.0215 0.0527
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0657 0.0555 0.0965
Echinococcus multilocularis dual specificity 0.1074 0.105 0.105
Echinococcus multilocularis MAM 0.032 0.0153 0.0153
Giardia lamblia Kinase, AGC AKT 0.0936 0.0886 0.7685
Echinococcus granulosus slit 2 protein 0.0257 0.0078 0.0135
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0204 0.0015 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0125 0.1046
Trichomonas vaginalis AGC family protein kinase 0.056 0.0439 0.3788
Echinococcus granulosus rho-associated protein kinase 1 0.0756 0.0673 0.117
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0235 0.0052 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Onchocerca volvulus 0.0861 0.0797 0.1053
Brugia malayi hypothetical protein 0.0232 0.0048 0.0048
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0204 0.0015 0.0017
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.0048 0.006
Brugia malayi Protein kinase domain containing protein 0.0285 0.0111 0.0133
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0207 0.0019 0.0033
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1074 0.105 0.1819
Trichomonas vaginalis CK1 family protein kinase 0.0584 0.0467 0.4038
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.0111 0.0272
Plasmodium vivax calcium-dependent protein kinase, putative 0.0517 0.0388 0.3574
Giardia lamblia Kinase, CAMK CAMKL 0.0361 0.0202 0.1656
Brugia malayi Serine/threonine-protein kinase SULU 0.2693 0.2978 0.4011
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) AUR protein kinase 0.056 0.0439 0.0588
Entamoeba histolytica protein kinase, putative 0.0196 0.0005 0.005
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0932 0.0882 0.1176
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0125 0.1046
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Brugia malayi hypothetical protein 0.0574 0.0455 0.0599
Giardia lamblia Kinase, STE STE20 0.0205 0.0016 0.0016
Entamoeba histolytica hypothetical protein, conserved 0.0232 0.0048 0.0447
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1296 0.1315 0.1315
Echinococcus granulosus Immunoglobulin 0.0573 0.0455 0.0791
Schistosoma mansoni ephrin receptor 0.0264 0.0087 0.0212
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.0762 0.068 0.0914
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica protein kinase, putative 0.1095 0.1076 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0517 0.0388 0.0675
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0205 0.0016 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0616 0.0506 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.0512 0.0381 0.0511
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.5022 0.5749 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0517 0.0388 0.3574
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis raf serine:threonine protein kinase 0.0376 0.022 0.022
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0385 0.023 0.2102
Schistosoma mansoni hypothetical protein 0.032 0.0153 0.0374
Echinococcus granulosus tyrosine protein kinase Src42A 0.1025 0.0992 0.1726
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1293 0.1312 0.2281
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0826 0.0755 0.0755
Brugia malayi tRNA modification GTPase TrmE family protein 0.0207 0.0019 0.0009
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2693 0.2978 0.518
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.042 0.0273 0.0363
Echinococcus granulosus casein kinase i 0.0584 0.0467 0.0813
Echinococcus granulosus activin receptor type 0.3819 0.4318 0.751
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0015 0.0087
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0201 0.0012 0.0063
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Trypanosoma brucei polo-like protein kinase 0.0296 0.0125 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.0048 0.0048
Plasmodium vivax serine/threonine protein kinase, putative 0.0203 0.0015 0.0086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica p21-activated kinase 0.0395 0.0243 0.2257
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0983 0.0942 0.0942
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0435 0.029 0.0387
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0114 0.0279
Echinococcus multilocularis PAK box P21 Rho binding 0.0331 0.0166 0.0166
Brugia malayi Hr1 repeat family protein 0.1579 0.1652 0.2217
Schistosoma mansoni nephrin 0.0295 0.0123 0.0302
Brugia malayi Protein kinase domain containing protein 0.1074 0.105 0.1403
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0232 0.0048 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0598 0.0485 0.1186
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0352 0.0191 0.0333
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0727 0.0637 0.0856
Echinococcus granulosus signal transduction protein lnk realted 0.0207 0.0019 0.0034
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2128 0.2305 0.3109
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1025 0.0992 0.1726
Brugia malayi Protein kinase domain containing protein 0.0401 0.025 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.1579 0.1652 0.4041
Leishmania major casein kinase II, putative 0.0221 0.0035 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.042 0.0273 0.0667
Loa Loa (eye worm) hypothetical protein 0.0722 0.0632 0.0848
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0232 0.0048 0.006
Onchocerca volvulus 0.0717 0.0625 0.0821
Schistosoma mansoni hypothetical protein 0.032 0.0153 0.0374
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1157 0.1149 0.1991
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Brugia malayi Protein kinase domain containing protein 0.0313 0.0146 0.018
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1014 0.098 0.1319
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Loa Loa (eye worm) hypothetical protein 0.0329 0.0164 0.0216
Echinococcus granulosus dual specificity 0.026 0.0081 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0125 0.1046
Echinococcus multilocularis serine:threonine protein kinase 3 0.0378 0.0222 0.0222
Brugia malayi Temporarily assigned gene name protein 59 0.0636 0.053 0.07
Schistosoma mansoni serine/threonine protein kinase 0.0983 0.0942 0.2305
Echinococcus multilocularis insulin receptor 0.1264 0.1277 0.1277
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0203 0.0015 0.0086
Brugia malayi MAP kinase sur-1 0.0204 0.0015 0.0004
Echinococcus granulosus neuroglian 0.0295 0.0123 0.0214
Echinococcus multilocularis tyrosine protein kinase shark 0.0653 0.055 0.055
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.0053 0.0414
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.278 0.308 0.4157
Schistosoma mansoni cell adhesion molecule 0.0295 0.0123 0.0302
Trichomonas vaginalis CMGC family protein kinase 0.042 0.0273 0.2336
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0296 0.0125 0.0217
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0277 0.0102 0.0102
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis c src tyrosine kinase 0.0604 0.0491 0.0491
Echinococcus granulosus dual specificity 0.026 0.0081 0.0141
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0023 0.0014
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Schistosoma mansoni protein kinase 0.0385 0.023 0.0564
Brugia malayi Protein kinase domain containing protein 0.2128 0.2305 0.3101
Echinococcus multilocularis calcium activated potassium channel 0.0319 0.0152 0.0152
Echinococcus multilocularis neuroglian 0.0295 0.0123 0.0123
Echinococcus granulosus neuroglian 0.0752 0.0667 0.116
Loa Loa (eye worm) hypothetical protein 0.0211 0.0023 0.0027
Echinococcus multilocularis dual specificity 0.026 0.0081 0.0081
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0385 0.023 0.0401
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1025 0.0992 0.0992
Plasmodium vivax serine/threonine kinase-1, putative 0.0965 0.092 0.8551
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Brugia malayi Protein kinase domain containing protein 0.1264 0.1277 0.171
Schistosoma mansoni shc transforming protein 0.0207 0.0019 0.0047
Echinococcus multilocularis expressed conserved protein 0.0255 0.0076 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.056 0.0439 0.1073
Schistosoma mansoni serine/threonine protein kinase 0.0691 0.0595 0.1455
Brugia malayi protein kinase C II. 0.0656 0.0553 0.0731
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0255 0.0076 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0688 0.0592 0.0795
Trichomonas vaginalis STE family protein kinase 0.0353 0.0192 0.1633
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.5022 0.5749 1
Echinococcus granulosus cyclin dependent kinase 1 0.042 0.0273 0.0474
Schistosoma mansoni titin 0.0211 0.0023 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0234 0.005 0.0394
Trypanosoma brucei cdc2-related kinase 3 0.042 0.0273 0.0465
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0011 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Brugia malayi Variant SH3 domain containing protein 0.0352 0.0191 0.0242
Loa Loa (eye worm) protein kinase domain-containing protein 0.0232 0.0048 0.006
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Echinococcus granulosus protein kinase C gamma type 0.0551 0.0429 0.0746
Loa Loa (eye worm) hypothetical protein 0.0717 0.0625 0.084
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0202 0.0013 0.0012
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0353 0.0192 0.0334
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0207 0.0019 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0152 0.0371
Echinococcus granulosus tyrosine protein kinase shark 0.0653 0.055 0.0956
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Entamoeba histolytica ankyrin repeat protein 0.0232 0.0048 0.0447
Schistosoma mansoni cell adhesion molecule 0.0295 0.0123 0.0302
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0232 0.0048 0.0373
Onchocerca volvulus Serine\/threonine kinase homolog 0.0296 0.0125 0.0143
Entamoeba histolytica hypothetical protein 0.0234 0.005 0.0469
Brugia malayi Immunoglobulin I-set domain containing protein 0.0435 0.029 0.0375
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Trypanosoma cruzi casein kinase II, putative 0.0221 0.0035 0.0051
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0207 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0329 0.0164 0.0275
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0247 0.0066 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0743 0.0657 0.0883
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0402 0.0251 0.0334
Giardia lamblia Kinase, CMGC CDK 0.042 0.0273 0.2274
Schistosoma mansoni serine/threonine protein kinase 0.0517 0.0388 0.0949
Trypanosoma cruzi Protein kinase B 0.032 0.0153 0.0257
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0743 0.0657 0.1143
Schistosoma mansoni cell adhesion molecule 0.0211 0.0023 0.0057
Onchocerca volvulus 0.0584 0.0467 0.0606
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0814 0.0741 0.1289
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0517 0.0388 0.0519
Onchocerca volvulus 0.0603 0.049 0.0638
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0221 0.0035 0.0276
Brugia malayi Protein kinase domain containing protein 0.057 0.0451 0.0593
Loa Loa (eye worm) hypothetical protein 0.0606 0.0493 0.0662
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0353 0.0192 0.0334
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.1035
Echinococcus multilocularis hemicentin 1 0.0262 0.0085 0.0085
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis peroxidasin 0.0265 0.0088 0.0088
Trichomonas vaginalis STE family protein kinase 0.0353 0.0192 0.1633
Schistosoma mansoni serine/threonine protein kinase 0.1293 0.1312 0.3209
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Echinococcus multilocularis casein kinase ii subunit alpha 0.0221 0.0035 0.0035
Echinococcus multilocularis SH2 domain containing protein 7 0.0207 0.0019 0.0019
Plasmodium falciparum NIMA related kinase 1 0.0257 0.0078 0.0678
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.079 0.0712 0.1239
Trichomonas vaginalis STE family protein kinase 0.0353 0.0192 0.1633
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.042 0.0273 0.0474
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0573 0.0455 0.1113
Echinococcus granulosus tyrosine protein kinase Fyn 0.1025 0.0992 0.1726
Echinococcus multilocularis SH2 motif 0.0207 0.0019 0.0019
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Entamoeba histolytica hypothetical protein 0.0234 0.0051 0.0478
Echinococcus granulosus protein kinase shaggy 0.1095 0.1076 0.1871
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0277 0.0102 0.0178
Entamoeba histolytica ankyrin repeat protein 0.0232 0.0048 0.0447
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Echinococcus granulosus protein tyrosine kinase 0.3626 0.4087 0.7109
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0207 0.0019 0.0034
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0232 0.0048 0.0373
Giardia lamblia Kinase, NEK 0.0257 0.0078 0.0558
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.217 0.2355 0.4096
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.051 0.038 0.0508
Trypanosoma brucei protein kinase, putative 0.0237 0.0054 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0257 0.0078 0.0634
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Entamoeba histolytica protein kinase, putative 0.0677 0.0578 0.5376
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0584 0.0467 0.0804
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.0595
Echinococcus granulosus tyrosine kinase 0.086 0.0796 0.1385
Entamoeba histolytica protein kinase domain containing protein 0.1095 0.1076 1
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0164 0.04
Loa Loa (eye worm) TK protein kinase 0.0232 0.0048 0.006
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0295 0.0123 0.0162
Echinococcus granulosus casein kinase I alpha 0.0584 0.0467 0.0813
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Brugia malayi Protein kinase domain containing protein 0.051 0.038 0.0497
Echinococcus multilocularis 0.0811 0.0738 0.0738
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0076 0.0186
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1157 0.1149 0.1991
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0232 0.0048 0.0084
Schistosoma mansoni protein kinase 0.0353 0.0192 0.047
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1074 0.105 0.1819
Brugia malayi Protein kinase domain containing protein 0.0334 0.017 0.0213
Echinococcus multilocularis SHC transforming protein 3 0.0207 0.0019 0.0019
Echinococcus granulosus epidermal growth factor receptor 0.0814 0.0741 0.1289
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Trichomonas vaginalis protein tyrosine kinase, putative 0.0232 0.0048 0.0373
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Echinococcus multilocularis casein kinase i 0.0584 0.0467 0.0467
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0484 0.0349 0.0349
Schistosoma mansoni suppressor of cytokine signaling 0.0207 0.0019 0.0047
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Schistosoma mansoni serine/threonine kinase 0.0434 0.0289 0.0706
Loa Loa (eye worm) hypothetical protein 0.0531 0.0404 0.0541
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0517 0.0388 0.0507
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0604 0.0491 0.1201
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0295 0.0123 0.0302
Onchocerca volvulus 0.0211 0.0023 0.0005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0204 0.0015 0.0016
Echinococcus multilocularis tyrosine protein kinase HCK 0.0653 0.0549 0.0549
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0232 0.0048 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni cell adhesion molecule 0.0211 0.0023 0.0057
Echinococcus granulosus beta-adrenergic receptor kinase 0.0287 0.0114 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis casein kinase I delta 0.0584 0.0467 0.0467
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1025 0.0992 0.0992
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1095 0.1076 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0232 0.0048 0.0118
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Echinococcus granulosus peroxidasin 0.0265 0.0088 0.0153
Giardia lamblia Kinase, CMGC DYRK 0.026 0.0081 0.0588
Leishmania major protein kinase, putative 0.0385 0.023 0.0392
Brugia malayi Protein kinase domain containing protein 0.1647 0.1733 0.2327
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Entamoeba histolytica receptor protein kinase, putative 0.0232 0.0048 0.0447
Schistosoma mansoni tensin-related 0.0207 0.0019 0.0047
Brugia malayi STE20-like kinase MST 0.0378 0.0222 0.0283
Entamoeba histolytica tyrosin kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2693 0.2978 0.2978
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0517 0.0388 0.3574
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.026 0.0081 0.0709
Schistosoma mansoni hypothetical protein 0.0207 0.0019 0.0047
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0207 0.0019 0.0019
Schistosoma mansoni protein kinase 0.0353 0.0192 0.047
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Onchocerca volvulus 0.0232 0.0048 0.0039
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1647 0.1733 0.2336
Trichomonas vaginalis AGC family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0015 0.0038
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.0595
Loa Loa (eye worm) hypothetical protein 0.092 0.0868 0.1168
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Brugia malayi Fes/CIP4 homology domain containing protein 0.076 0.0677 0.0899
Schistosoma mansoni tyrosine kinase 0.1264 0.1277 0.3123
Schistosoma mansoni serine/threonine protein kinase 0.051 0.038 0.093
Entamoeba histolytica protein kinase, putative 0.0196 0.0005 0.005
Brugia malayi hypothetical protein 0.0606 0.0493 0.065
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0296 0.0125 0.0125
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0207 0.0019 0.0019
Trichomonas vaginalis AGC family protein kinase 0.051 0.038 0.3275
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0385 0.023 0.0392
Echinococcus granulosus tyrosine protein kinase ABL1 0.2159 0.2342 0.4073
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.056 0.0439 0.4078
Echinococcus multilocularis casein kinase I alpha 0.0584 0.0467 0.0467
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2063 0.2228 0.3005
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1296 0.1315 0.2288
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0236 0.0053 0.0053
Schistosoma mansoni protein kinase 0.234 0.2557 0.6257
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Echinococcus multilocularis serine threonine protein kinase 0.0551 0.0429 0.0429
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0125 0.1046
Entamoeba histolytica protein kinase , putative 0.056 0.0439 0.4078
Plasmodium vivax unspecified product 0.0221 0.0035 0.0276
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Loa Loa (eye worm) hypothetical protein 0.0463 0.0323 0.0432
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0076 0.0186
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0584 0.0467 0.0626
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.0595
Brugia malayi Variant SH3 domain containing protein 0.0372 0.0215 0.0274
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0262 0.0085 0.011
Schistosoma mansoni serine/threonine protein kinase 0.1074 0.105 0.2569
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni protein kinase 0.0232 0.0048 0.0118
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1492 0.1548 0.2086
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Entamoeba histolytica PH domain containing protein kinase, putative 0.0734 0.0645 0.6002
Loa Loa (eye worm) TK/RYK protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis serine:threonine protein kinase 0.0319 0.0152 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0152 0.0371
Onchocerca volvulus 0.032 0.0153 0.0181
Echinococcus granulosus twitchin 0.0905 0.0849 0.1477
Entamoeba histolytica protein kinase, putative 0.0518 0.0389 0.362
Loa Loa (eye worm) AGC/AKT protein kinase 0.0677 0.0578 0.0776
Toxoplasma gondii aurora kinase 0.056 0.0439 0.4048
Echinococcus granulosus mitogen activated protein kinase 11 0.5022 0.5749 1
Giardia lamblia Kinase, CAMK CAMKL 0.0361 0.0202 0.1656
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0232 0.0048 0.0048
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Onchocerca volvulus 0.0232 0.0048 0.0039
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1095 0.1076 0.1871
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.2128 0.2305 0.5639
Trichomonas vaginalis AGC family protein kinase 0.0543 0.0419 0.3615
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0361 0.0202 0.1841
Loa Loa (eye worm) AUR protein kinase 0.056 0.0439 0.0588
Trichomonas vaginalis CMGC family protein kinase 0.042 0.0273 0.2336
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0023 0.0014
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0262 0.0085 0.0207
Loa Loa (eye worm) gastrulation defective protein 1 0.1494 0.155 0.209
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0965 0.092 0.1593
Echinococcus granulosus kinase suppressor of Ras 1 0.0232 0.0048 0.0084
Loa Loa (eye worm) TK/ABL protein kinase 0.2159 0.2342 0.3159
Schistosoma mansoni serine/threonine protein kinase 0.0696 0.0601 0.147
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.051 0.038 0.0661
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis casein kinase I alpha 0.0584 0.0467 0.0467
Echinococcus multilocularis roundabout 2 0.0295 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0221 0.0035 0.0258
Plasmodium falciparum glycogen synthase kinase 3 0.1095 0.1076 1
Echinococcus multilocularis titin 0.0364 0.0206 0.0206
Echinococcus granulosus cyclin dependent kinase 9 0.034 0.0177 0.0307
Echinococcus granulosus SH2 motif 0.0207 0.0019 0.0034
Schistosoma mansoni tyrosine kinase 0.0953 0.0907 0.2219
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi Protein kinase domain containing protein 0.4636 0.529 0.7139
Entamoeba histolytica protein kinase domain containing protein 0.0273 0.0097 0.0903
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1823 0.1942 0.261
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0517 0.0388 0.3574
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Schistosoma mansoni titin 0.0364 0.0206 0.0503
Echinococcus granulosus natriuretic peptide receptor 1 0.0232 0.0048 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0965 0.092 0.8002
Brugia malayi Variant SH3 domain containing protein 0.0251 0.0072 0.008
Echinococcus granulosus SH2 domain containing adapter protein F 0.0207 0.0019 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0401 0.025 0.2137
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0207 0.0019 0.0009
Onchocerca volvulus 0.0352 0.0191 0.0233
Echinococcus granulosus calcium activated potassium channel 0.0319 0.0152 0.0264
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0372 0.0215 0.0286
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0636 0.053 0.0913
Echinococcus granulosus casein kinase I alpha 0.0584 0.0467 0.0813
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Echinococcus granulosus raf serine:threonine protein kinase 0.0376 0.022 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0155 0.0379
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1823 0.1942 0.2619
Giardia lamblia Kinase 0.0232 0.0048 0.0295
Brugia malayi Protein kinase domain containing protein 0.217 0.2355 0.3168
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0232 0.0048 0.0048
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0203 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0164 0.04
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0232 0.0048 0.0373
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis serine:threonine protein kinase N2 0.1579 0.1652 0.1652
Echinococcus multilocularis mitogen activated protein kinase 14 0.5022 0.5749 0.5749
Leishmania major protein kinase, putative 0.0965 0.092 0.1593
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0221 0.0035 0.0042
Trypanosoma brucei casein kinase I, isoform 2 0.0584 0.0467 0.0804
Echinococcus multilocularis tyrosine protein kinase Srms 0.086 0.0796 0.0796
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0048 0.0118
Schistosoma mansoni tyrosine kinase 0.1359 0.139 0.34
Entamoeba histolytica protein kinase, putative 0.0202 0.0013 0.0118
Brugia malayi serine/threonine protein kinase 6 0.056 0.0439 0.0576
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0232 0.0048 0.0074
Entamoeba histolytica PH domain containing protein kinase, putative 0.032 0.0153 0.1423
Echinococcus multilocularis twitchin 0.0332 0.0167 0.0167
Trichomonas vaginalis AGC family protein kinase 0.056 0.0439 0.3788
Echinococcus granulosus tyrosine protein kinase Lyn 0.1178 0.1175 0.2043
Echinococcus granulosus protein kinase c epsilon type 0.0656 0.0553 0.0963
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.468 0.5343 0.9293
Echinococcus granulosus N chimaerin 0.0352 0.0191 0.0333
Giardia lamblia Protein 21.1 0.0232 0.0048 0.0295
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Trypanosoma cruzi casein kinase, putative 0.0584 0.0467 0.0804
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.051 0.038 0.093
Brugia malayi Tyrosine-protein kinase PR2 0.0232 0.0048 0.0048
Echinococcus multilocularis protein tyrosine kinase 0.3626 0.4087 0.4087
Schistosoma mansoni protein kinase 0.1532 0.1596 0.3904
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.234 0.2557 0.2557
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Echinococcus granulosus expressed conserved protein 0.0207 0.0019 0.0034
Echinococcus granulosus receptor type guanylyl cyclase 0.0232 0.0048 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Leishmania major protein kinase, putative 0.0205 0.0016 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.042 0.0273 0.2336
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.026 0.0081 0.0093
Trypanosoma brucei Flagellum attachment zone protein 20 0.0232 0.0048 0.0074
Entamoeba histolytica protein kinase, putative 0.0196 0.0005 0.005
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0232 0.0048 0.0084
Echinococcus granulosus casein kinase I gamma 0.0334 0.017 0.0296
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.0013 0.0031
Loa Loa (eye worm) AGC/PKA protein kinase 0.0691 0.0595 0.0799
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0232 0.0048 0.006
Echinococcus granulosus hypothetical protein 0.0811 0.0738 0.1284
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0201 0.0012 0.0063
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0211 0.0023 0.0041
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0517 0.0388 0.3574
Onchocerca volvulus 0.0439 0.0295 0.0373
Echinococcus multilocularis FL cytokine receptor 0.0232 0.0048 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1358 0.1388 0.1871
Echinococcus granulosus serine:threonine protein kinase 3 0.0378 0.0222 0.0386
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0204 0.0015 0.0017
Echinococcus granulosus casein kinase I alpha 0.0584 0.0467 0.0813
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0123 0.015
Echinococcus multilocularis rho associated protein kinase 0.0756 0.0673 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0015 0.0036
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0353 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0691 0.0595 0.0799
Echinococcus granulosus serine:threonine protein kinase 12 B 0.056 0.0439 0.0763
Loa Loa (eye worm) TK protein kinase 0.0232 0.0048 0.006
Echinococcus granulosus TGF-beta receptor type-1 0.0826 0.0755 0.1313
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis STE family protein kinase 0.0205 0.0016 0.0097
Brugia malayi STAT protein, DNA binding domain containing protein 0.0207 0.0019 0.0009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0015 0.0087
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0232 0.0048 0.0084
Entamoeba histolytica casein kinase, putative 0.0584 0.0467 0.4343
Echinococcus granulosus expressed protein 0.0203 0.0015 0.0025
Trypanosoma cruzi cdc2-related kinase 3 0.042 0.0273 0.0465
Giardia lamblia Kinase, CMGC CK2 0.0221 0.0035 0.0179
Brugia malayi EGF-like domain containing protein 0.0257 0.0078 0.0088
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.0048 0.006
Loa Loa (eye worm) hypothetical protein 0.0211 0.0023 0.0027
Entamoeba histolytica PH domain containing protein kinase, putative 0.0734 0.0645 0.6002
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0232 0.0048 0.0048
Trypanosoma cruzi aurora B kinase, putative 0.056 0.0439 0.0754
Entamoeba histolytica receptor protein kinase, putative 0.0232 0.0048 0.0447
Schistosoma mansoni tyrosine kinase 0.0446 0.0303 0.0741
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Entamoeba histolytica protein kinase, putative 0.0677 0.0578 0.5376
Echinococcus multilocularis serine:threonine protein kinase 38 0.051 0.038 0.038
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Entamoeba histolytica hypothetical protein 0.0196 0.0005 0.005
Brugia malayi bone morphogenetic protein type 1 receptor 0.0904 0.0848 0.113
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0011 0.0045
Giardia lamblia Kinase, NEK 0.0232 0.0048 0.0295
Loa Loa (eye worm) protein kinase domain-containing protein 0.0334 0.017 0.0225
Loa Loa (eye worm) AGC/NDR protein kinase 0.051 0.038 0.0508
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0636 0.053 0.1296
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0085 0.0097
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.079 0.0712 0.0712
Giardia lamblia Kinase, AGC PKA 0.0691 0.0595 0.5115
Echinococcus granulosus retinal guanylyl cyclase 2 0.0232 0.0048 0.0084
Loa Loa (eye worm) TK protein kinase 0.086 0.0796 0.1071
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.051 0.038 0.038
Echinococcus granulosus Protein kinase C brain isozyme 0.0696 0.0601 0.1045
Schistosoma mansoni hypothetical protein 0.0207 0.0019 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Brugia malayi protein kinase C3,putative 0.0381 0.0226 0.0288
Brugia malayi Protein kinase domain 0.0353 0.0192 0.0243
Trichomonas vaginalis AGC family protein kinase 0.0235 0.0052 0.0404
Entamoeba histolytica protein kinase domain containing protein 0.0385 0.023 0.2142
Brugia malayi Variant SH3 domain containing protein 0.0372 0.0215 0.0274
Entamoeba histolytica hypothetical protein 0.0234 0.0051 0.0478
Loa Loa (eye worm) hypothetical protein 0.0232 0.0048 0.006
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica protein kinase, putative 0.0517 0.0388 0.3606
Brugia malayi Raf kinase 0.0232 0.0048 0.0048
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis cyclin dependent kinase 0.042 0.0273 0.0273
Brugia malayi Protein kinase domain containing protein 0.0439 0.0295 0.0382
Schistosoma mansoni protein tyrosine kinase 0.0232 0.0048 0.0118
Brugia malayi Protein kinase domain containing protein 0.0722 0.0632 0.0837
Echinococcus multilocularis protein kinase shaggy 0.1095 0.1076 0.1076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0085 0.0097
Onchocerca volvulus 0.0232 0.0048 0.0039
Schistosoma mansoni tensin 0.0207 0.0019 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Toxoplasma gondii histone kinase SNF1, putative 0.0329 0.0164 0.1478
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1025 0.0992 0.0992
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Giardia lamblia Kinase, NEK 0.0232 0.0048 0.0295
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0295 0.0123 0.0214
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0691 0.0595 0.1035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0606 0.0493 0.065
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0691 0.0595 0.1026
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.042 0.0273 0.0465
Toxoplasma gondii protein kinase 0.0232 0.0048 0.0398
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Schistosoma mansoni tyrosine kinase 0.0604 0.0491 0.1201
Loa Loa (eye worm) hypothetical protein 0.0515 0.0386 0.0517
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0691 0.0595 0.5508
Brugia malayi SH2 domain containing protein 0.0207 0.0019 0.0009
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0448 0.0306 0.0408
Echinococcus granulosus tumor protein p63 0.033 0.0165 0.0286
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Onchocerca volvulus Tyrosine kinase homolog 0.2737 0.303 0.4076
Echinococcus multilocularis tyrosine kinase 0.0439 0.0295 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Leishmania major hypothetical protein, conserved 0.0232 0.0048 0.0074
Onchocerca volvulus 0.0232 0.0048 0.0039
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0364 0.0206 0.0273
Loa Loa (eye worm) TK protein kinase 0.0232 0.0048 0.006
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Entamoeba histolytica protein kinase, putative 0.0353 0.0192 0.1786
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0232 0.0048 0.0118
Schistosoma mansoni vav2 0.0395 0.0242 0.0592
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0205 0.0016 0.0153
Brugia malayi Immunoglobulin I-set domain containing protein 0.0364 0.0206 0.0261
Entamoeba histolytica protein kinase, putative 0.0331 0.0166 0.1545
Schistosoma mansoni protein kinase C mu 0.1014 0.098 0.2397
Entamoeba histolytica protein kinase, putative 0.0634 0.0528 0.4905
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0896 0.0839 0.1128
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0378 0.0222 0.0295
Brugia malayi cell division control protein 2 homolog 0.042 0.0273 0.0352
Onchocerca volvulus 0.0318 0.0151 0.0178
Schistosoma mansoni roundabout 0.0262 0.0085 0.0207
Echinococcus multilocularis mitogen activated protein kinase 3 0.0204 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase pr2 0.0232 0.0048 0.0084
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1358 0.1388 0.1871
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0329 0.0164 0.0275
Brugia malayi hypothetical protein 0.0232 0.0048 0.0048
Brugia malayi map kinase activated protein kinase protein 2 0.0515 0.0386 0.0505
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0204 0.0015 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0081 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0756 0.0673 0.1646
Echinococcus granulosus Vam6:Vps39 protein 0.0636 0.053 0.0922
Schistosoma mansoni tyrosine kinase 0.0814 0.0741 0.1813
Onchocerca volvulus Slit protein homolog 0.0257 0.0078 0.0079
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2253 0.2454 0.4268
Brugia malayi Protein kinase c protein 2 0.0339 0.0176 0.022
Loa Loa (eye worm) CAMK/PKD protein kinase 0.087 0.0808 0.1086
Schistosoma mansoni tyrosine kinase 0.0582 0.0466 0.1139
Trichomonas vaginalis CK1 family protein kinase 0.0584 0.0467 0.4038
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0232 0.0048 0.0039
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0722 0.0632 0.0848
Brugia malayi Sex muscle abnormal protein 5 0.0372 0.0215 0.0274
Onchocerca volvulus 0.0232 0.0048 0.0039
Echinococcus multilocularis dual specificity protein kinase clk2 0.0965 0.092 0.092
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0232 0.0048 0.0039
Loa Loa (eye worm) hypothetical protein 0.0712 0.062 0.0833
Schistosoma mansoni hypothetical protein 0.0211 0.0023 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.1074 0.105 0.9763
Schistosoma mansoni tyrosine kinase 0.0232 0.0048 0.0118
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0232 0.0048 0.0118
Echinococcus granulosus tyrosine protein kinase Fyn 0.1025 0.0992 0.1726
Entamoeba histolytica serine/threonine protein kinase, putative 0.0296 0.0125 0.1163
Loa Loa (eye worm) TK protein kinase 0.0536 0.041 0.0549
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0207 0.0019 0.0019
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0353 0.0192 0.0334
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis growth factor receptor bound protein 2 0.0372 0.0215 0.0215
Loa Loa (eye worm) TK protein kinase 0.0653 0.0549 0.0738
Schistosoma mansoni serine/threonine protein kinase 0.0656 0.0553 0.1354
Plasmodium falciparum calcium-dependent protein kinase 5 0.0517 0.0388 0.3574
Loa Loa (eye worm) hypothetical protein 0.0207 0.0019 0.0021
Loa Loa (eye worm) serine/threonine protein kinase 0.0232 0.0048 0.006
Echinococcus multilocularis dual specificity mitogen activated protein 0.1157 0.1149 0.1149
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0247 0.0066 0.0115
Entamoeba histolytica PH domain containing protein kinase, putative 0.0196 0.0005 0.005
Schistosoma mansoni cell adhesion molecule 0.069 0.0593 0.1452
Echinococcus multilocularis serine:threonine protein kinase N2 0.051 0.038 0.038
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0517 0.0388 0.0675
Echinococcus multilocularis signal transduction protein lnk realted 0.0207 0.0019 0.0019
Echinococcus granulosus hypothetical protein 0.0207 0.0019 0.0034
Brugia malayi serine/threonine-protein kinase PAK 7 0.2063 0.2228 0.2996
Schistosoma mansoni serine/threonine kinase 0.051 0.038 0.093
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Plasmodium falciparum protein kinase, putative 0.0385 0.023 0.2102
Schistosoma mansoni protein kinase 0.0826 0.0755 0.1847
Toxoplasma gondii protein kinase domain-containing protein 0.0232 0.0048 0.0398
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0207 0.0019 0.0034
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.5022 0.5749 0.7763
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0295 0.0123 0.0123
Onchocerca volvulus 0.0439 0.0295 0.0373
Onchocerca volvulus 0.0364 0.0206 0.0252
Entamoeba histolytica PH domain containing protein kinase, putative 0.032 0.0153 0.1423
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0232 0.0048 0.0048
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) TK/FAK protein kinase 0.3666 0.4135 0.5583
Loa Loa (eye worm) hypothetical protein 0.0712 0.062 0.0833
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0265 0.0088 0.0088
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0965 0.092 0.1593
Trichomonas vaginalis CAMK family protein kinase 0.0319 0.0152 0.1279
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0232 0.0048 0.0048
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0691 0.0595 0.1026
Echinococcus multilocularis protein kinase 0.0232 0.0048 0.0048
Echinococcus multilocularis 0.0207 0.0019 0.0019
Echinococcus multilocularis Immunoglobulin 0.0573 0.0455 0.0455
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.042 0.0273 0.0363
Plasmodium vivax glycogen synthase kinase 3, putative 0.1095 0.1076 1
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0015 0.0087
Echinococcus granulosus ephrin type A receptor 4 A 0.0296 0.0124 0.0216
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0204 0.0015 0.0017
Schistosoma mansoni hypothetical protein 0.0232 0.0048 0.0118
Loa Loa (eye worm) SH2 domain-containing protein 0.0207 0.0019 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0517 0.0388 0.3344
Loa Loa (eye worm) hypothetical protein 0.092 0.0868 0.1168
Brugia malayi Protein kinase domain containing protein 0.0402 0.0251 0.0322
Loa Loa (eye worm) hypothetical protein 0.0606 0.0493 0.0662
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Entamoeba histolytica protein kinase, putative 0.1074 0.105 0.9763
Brugia malayi SH2 domain containing protein 0.0439 0.0295 0.0382
Loa Loa (eye worm) AGC/PKG protein kinase 0.0255 0.0076 0.0098
Loa Loa (eye worm) thyroid receptor interactor 0.076 0.0677 0.091
Loa Loa (eye worm) IKK protein kinase 0.6413 0.7405 1
Entamoeba histolytica protein kinase, putative 0.056 0.0439 0.4078
Echinococcus granulosus protein kinase 0.0232 0.0048 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Loa Loa (eye worm) TK/ACK protein kinase 0.0232 0.0048 0.006
Trypanosoma cruzi rac serine-threonine kinase, putative 0.032 0.0153 0.0257
Echinococcus granulosus serine threonine protein kinase nrc 0.0277 0.0102 0.0178
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0691 0.0595 0.0788
Echinococcus multilocularis protein kinase 0.0232 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0573 0.0455 0.061
Brugia malayi C-terminal src kinase protein 1 0.0232 0.0048 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Onchocerca volvulus 0.0211 0.0023 0.0005
Echinococcus granulosus dual specificity 0.026 0.0081 0.0141
Loa Loa (eye worm) hypothetical protein 0.1223 0.1228 0.1654
Brugia malayi Protein kinase domain containing protein 0.0417 0.0269 0.0346
Echinococcus multilocularis kinase suppressor of Ras 1 0.0232 0.0048 0.0048
Trichomonas vaginalis AGC family protein kinase 0.051 0.038 0.3275
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0387 0.0233 0.031
Loa Loa (eye worm) hypothetical protein 0.4084 0.4632 0.6254
Loa Loa (eye worm) hypothetical protein 0.1379 0.1414 0.1905
Onchocerca volvulus 0.0439 0.0295 0.0373
Echinococcus granulosus titin 0.0364 0.0206 0.0358
Loa Loa (eye worm) TK/DDR protein kinase 0.0232 0.0048 0.006
Loa Loa (eye worm) SRC-1 0.1025 0.0992 0.1336
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2693 0.2978 0.4018
Echinococcus granulosus serine:threonine kinase SAD 1 0.0329 0.0164 0.0284
Loa Loa (eye worm) hypothetical protein 0.0262 0.0085 0.011
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0965 0.092 0.1593
Plasmodium falciparum calcium-dependent protein kinase 2 0.0517 0.0388 0.3574
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.0048 0.0447
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.056 0.0439 0.4078
Entamoeba histolytica casein kinase, putative 0.0221 0.0035 0.0325
Plasmodium falciparum protein kinase, putative 0.0232 0.0048 0.0398
Schistosoma mansoni tyrosine kinase 0.0582 0.0466 0.1139
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1386
Loa Loa (eye worm) TK/INSR protein kinase 0.1264 0.1277 0.172
Brugia malayi Protein kinase domain containing protein 0.0439 0.0295 0.0382
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0295 0.0123 0.0123
Plasmodium falciparum serine/threonine protein kinase, putative 0.056 0.0439 0.4048
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Brugia malayi casein kinase 1, delta 0.0584 0.0467 0.0615
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0232 0.0048 0.0048
Echinococcus multilocularis dual specificity 0.026 0.0081 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0081 0.0756
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0402 0.0251 0.0251
Loa Loa (eye worm) TK/ROR protein kinase 0.041 0.026 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0965 0.092 0.2252
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0015 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.051 0.038 0.0661
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.0836 0.0767 0.1031
Trichomonas vaginalis protein kinase atn1, putative 0.0232 0.0048 0.0373
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0232 0.0048 0.0048
Echinococcus granulosus roundabout 2 0.0295 0.0123 0.0214
Trichomonas vaginalis TKL family protein kinase 0.0232 0.0048 0.0373
Entamoeba histolytica protein kinase, putative 0.0203 0.0015 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0048 0.0118
Brugia malayi RhoGAP domain containing protein 0.0352 0.0191 0.0242
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0517 0.0388 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0349 0.0853
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0295 0.0123 0.0123
Schistosoma mansoni kinase 0.0362 0.0203 0.0496
Echinococcus multilocularis transfer RNA-Phe 0.0211 0.0023 0.0023
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.0048 0.0447
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0691 0.0595 0.1026
Echinococcus granulosus protein kinase c iota type 0.0738 0.0651 0.1132
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0295 0.0123 0.0123
Entamoeba histolytica hypothetical protein 0.0232 0.0048 0.0447
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Echinococcus granulosus dual specificity 0.1074 0.105 0.1826
Echinococcus granulosus tyrosine protein kinase Fyn 0.1025 0.0992 0.1726
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0691 0.0595 0.1026
Echinococcus granulosus NCK adaptor protein 0.0372 0.0215 0.0375
Brugia malayi Tyrosine-protein kinase abl-1 0.1062 0.1037 0.1385
Trypanosoma cruzi cdc2-related kinase 1 0.042 0.0273 0.0465
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1293 0.1312 0.1767
Onchocerca volvulus 0.0756 0.0673 0.0885
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0323 0.0157 0.0196
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Entamoeba histolytica tyrosin kinase, putative 0.0232 0.0048 0.0447
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.0048 0.0447
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2128 0.2305 0.2305
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0656 0.0553 0.0743
Trypanosoma brucei protein kinase, putative 0.1095 0.1076 0.1863
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0164 0.04
Schistosoma mansoni protein kinase 0.1157 0.1149 0.2811
Echinococcus granulosus epidermal growth factor receptor 0.0953 0.0907 0.1577
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.5022 0.5749 1
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0048 0.0373
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0357 0.0198 0.1681
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1095 0.1076 0.2631
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0691 0.0595 0.5508
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Brugia malayi Protein kinase domain containing protein 0.042 0.0273 0.0352
Loa Loa (eye worm) hypothetical protein 0.0712 0.062 0.0833
Echinococcus granulosus tyrosine protein kinase Src42A 0.0644 0.0539 0.0938
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.5022 0.5749 1
Schistosoma mansoni serine/threonine protein kinase 0.0932 0.0882 0.2158
Trichomonas vaginalis AGC family protein kinase 0.0677 0.0578 0.5009
Loa Loa (eye worm) hypothetical protein 0.0861 0.0797 0.1073
Plasmodium falciparum cGMP-dependent protein kinase 0.0255 0.0076 0.066
Trichomonas vaginalis CMGC family protein kinase 0.026 0.0081 0.0664
Loa Loa (eye worm) TK/FER protein kinase 0.0439 0.0295 0.0394
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0211 0.0023 0.0027
Echinococcus multilocularis receptor type guanylyl cyclase 0.0232 0.0048 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0329 0.0164 0.1383
Schistosoma mansoni growth factor receptor-bound protein 0.0372 0.0215 0.0527
Schistosoma mansoni protein kinase 0.0904 0.0848 0.2076
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0636 0.053 0.1296
Schistosoma mansoni protein kinase 0.217 0.2355 0.5761
Echinococcus granulosus casein kinase I delta 0.0584 0.0467 0.0813
Loa Loa (eye worm) hypothetical protein 0.0657 0.0555 0.0745
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0207 0.0019 0.0019
Schistosoma mansoni protein kinase 0.0385 0.023 0.0564
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0296 0.0125 0.0208
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0085 0.0097
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1358 0.1388 0.2415
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0271 0.0095 0.0124
Schistosoma mansoni serine/threonine RGC 0.0232 0.0048 0.0118
Echinococcus granulosus MAM 0.032 0.0153 0.0266
Loa Loa (eye worm) hypothetical protein 0.0262 0.0085 0.011
Echinococcus multilocularis epidermal growth factor receptor 0.0814 0.0741 0.0741
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1358 0.1388 0.1861
Trypanosoma cruzi casein kinase, putative 0.0584 0.0467 0.0804
Leishmania major protein kinase, putative 0.0965 0.092 0.1593
Echinococcus granulosus tyrosine protein kinase 0.0232 0.0048 0.0084
Echinococcus granulosus serine:threonine protein kinase N2 0.1069 0.1044 0.1816
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.0048 0.0447
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0352 0.0191 0.0468
Schistosoma mansoni serine/threonine-protein kinase 0.032 0.0153 0.0374
Schistosoma mansoni nephrin 0.0784 0.0706 0.1727
Loa Loa (eye worm) SH2 domain-containing protein 0.0207 0.0019 0.0021
Echinococcus multilocularis beta adrenergic receptor kinase 0.0287 0.0114 0.0114
Echinococcus multilocularis activin receptor type 0.3819 0.4318 0.4318
Echinococcus granulosus TGF beta receptor type 1 0.0826 0.0755 0.1313
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0512 0.0381 0.0511
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0691 0.0595 0.5508
Brugia malayi Doublecortin family protein 0.0271 0.0095 0.0112
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0202 0.0013 0.0022
Echinococcus multilocularis N chimaerin 0.0352 0.0191 0.0191
Echinococcus granulosus SH2 domain containing protein 7 0.0207 0.0019 0.0034
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0234 0.0051 0.0478
Brugia malayi Protein kinase domain containing protein 0.0232 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0376 0.022 0.0538
Echinococcus multilocularis NCK adaptor protein 0.0387 0.0234 0.0234
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.0047 0.0047
Schistosoma mansoni hemicentin 0.0211 0.0023 0.0057
Loa Loa (eye worm) hypothetical protein 0.0889 0.0831 0.1117
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Echinococcus multilocularis SH2 motif 0.0207 0.0019 0.0019
Entamoeba histolytica protein kinase, putative 0.0232 0.0048 0.0447
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.057 0.0451 0.0604
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0207 0.0019 0.0047

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 0 % Displacement of [3H]SCH23390 from pig dopamine D1 receptor at 100 nM ChEMBL. 19481941
Activity (binding) = 20 % Displacement of [3H]spiperone from human cloned dopamine D2 long receptor expressed in CHO cells at 100 nM ChEMBL. 19481941
Activity (binding) = 20 % Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells at 100 nM ChEMBL. 19481941
Activity (binding) = 80 % Displacement of [3H]spiperone from human cloned dopamine D4.4 receptor expressed in CHO cells at 100 nM ChEMBL. 19481941
Ki (binding) = 6.4 nM Displacement of [3H]spiroperidol from human cloned dopamine D4.4 receptor expressed in CHO cells ChEMBL. 19481941
Ki (binding) = 2600 nM Displacement of [3H]SCH23390 from human cloned dopamine D2 long receptor expressed in CHO cells ChEMBL. 19481941
Ki (binding) = 2900 nM Displacement of [3H]spiroperidol from human cloned dopamine D2 short receptor expressed in CHO cells ChEMBL. 19481941
Ki (binding) = 6100 nM Displacement of [3H]spiroperidol from human cloned dopamine D3 receptor expressed in CHO cells ChEMBL. 19481941
Ki (binding) = 6800 nM Displacement of [3H]SCH23390 from bovine dopamine D1 receptor ChEMBL. 19481941

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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