Detailed information for compound 1100309

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 239.206 | Formula: C8H18NO5P
  • H donors: 3 H acceptors: 5 LogP: -0.92 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(P(=O)(O)O)CCN(C(=O)C)O
  • InChi: 1S/C8H18NO5P/c1-3-4-8(15(12,13)14)5-6-9(11)7(2)10/h8,11H,3-6H2,1-2H3,(H2,12,13,14)
  • InChiKey: JTGWCTDCLRMUIK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli 1-deoxy-D-xylulose 5-phosphate reductoisomerase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Neospora caninum 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium yoelii 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras Get druggable targets OG5_130462 All targets in OG5_130462
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Babesia bovis 1-deoxy-D-xylulose 5-phosphate reductoisomerase family protein Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium knowlesi 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Theileria parva 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
Plasmodium berghei 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative Get druggable targets OG5_130462 All targets in OG5_130462
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Onchocerca volvulus 0.0065 0.0416 0.2423
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Schistosoma mansoni neuroligin 3 (S09 family) 0.0229 0.1635 0.1634
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Brugia malayi Carboxylesterase family protein 0.0229 0.1635 0.1634
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0015 0.0013
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0016 0.0037
Entamoeba histolytica cysteine protease, putative 0.0016 0.0056 0.0265
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.008 0.008
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Brugia malayi MH2 domain containing protein 0.0361 0.2619 0.2618
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0117 0.0116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0006 0.0005
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0053 0.0325 0.0325
Brugia malayi larval opioid receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0038 0.0216 0.101
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0013 0.0011
Giardia lamblia Cathepsin L precursor 0.0016 0.0056 0.0006
Onchocerca volvulus 0.0065 0.0416 0.2423
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0214 0.0425
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0086
Onchocerca volvulus 0.0065 0.0416 0.2423
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0845 0.0843
Plasmodium falciparum pyruvate kinase 0.0033 0.018 0.047
Schistosoma mansoni neuropeptide receptor 0.0065 0.0416 0.0414
Plasmodium falciparum serine repeat antigen 7 0.0016 0.0056 0.0144
Schistosoma mansoni gliotactin 0.0229 0.1635 0.1634
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1316
Echinococcus multilocularis pyruvate kinase 0.0017 0.006 0.0059
Plasmodium vivax glutathione reductase, putative 0.0047 0.0282 0.0705
Onchocerca volvulus 0.003 0.0161 0.0933
Echinococcus multilocularis dro:myosuppressin receptor 0.0065 0.0416 0.0414
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0016 0.0056 0.0107
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0416 0.0414
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0014 0.0012
Giardia lamblia Cathepsin L precursor 0.0016 0.0056 0.0006
Plasmodium falciparum serine repeat antigen 2 0.0016 0.0056 0.0144
Trichomonas vaginalis glutaminase, putative 0.0278 0.2002 0.9714
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0085
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0016 0.0056 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.008 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0305 0.1425
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0165 0.0794
Onchocerca volvulus 0.005 0.0306 0.1779
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1219
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0016 0.0056 0.0055
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1219
Brugia malayi hypothetical protein 0.0229 0.1635 0.1634
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus granulosus 7tm_1 domain containing protein 0.0065 0.0416 0.0414
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0014 0.0012
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0306 0.0304
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0115 0.0115
Brugia malayi Bromodomain containing protein 0.0092 0.0615 0.0614
Brugia malayi Melatonin receptor type 1A 0.0065 0.0416 0.0414
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0363 0.0361
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.005 0.0306 0.0306
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0281 0.2021 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0056 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0006 0.0005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0271 0.0269
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0085
Giardia lamblia Cathepsin B precursor 0.0016 0.0056 0.0006
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0016 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0165 0.074
Loa Loa (eye worm) fibroinase 0.0053 0.0325 0.0325
Echinococcus granulosus muscleblind protein 0.0149 0.1043 0.1041
Loa Loa (eye worm) TYRA-2 protein 0.0065 0.0416 0.0416
Entamoeba histolytica cysteine protease, putative 0.0016 0.0056 0.0265
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0363 0.5375
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.008 0.103
Schistosoma mansoni hypothetical protein 0.017 0.1197 0.1195
Brugia malayi Thioredoxin reductase 0.0047 0.0282 0.028
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0305 0.1425
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0305 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0006 0.0005
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.018 0.047
Onchocerca volvulus 0.0054 0.0332 0.1933
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0016 0.0016
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.013 0.0309
Brugia malayi hypothetical protein 0.001 0.0006 0.0005
Schistosoma mansoni ran 0.0042 0.025 0.0248
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Schistosoma mansoni ap endonuclease 0.0038 0.0214 0.0213
Echinococcus multilocularis lamin 0.0027 0.0133 0.0131
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0165 0.0794
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0086 0.0085
Echinococcus multilocularis orexin receptor type 2 0.0065 0.0416 0.0414
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0085
Brugia malayi Cytochrome P450 family protein 0.0011 0.0013 0.0011
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0464 0.1192
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0053 0.0325 0.1519
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0305 0.1425
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0084 0.0082
Schistosoma mansoni hypothetical protein 0.0616 0.4506 0.4505
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0416 0.0416
Echinococcus multilocularis GPCR, family 2 0.0079 0.0519 0.0517
Loa Loa (eye worm) hypothetical protein 0.0051 0.031 0.031
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0214 0.0982
Echinococcus granulosus dna polymerase eta 0.002 0.008 0.0078
Echinococcus granulosus G protein coupled receptor 139 0.0065 0.0416 0.0414
Plasmodium falciparum glutathione reductase 0.0047 0.0282 0.074
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0086 0.0086
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0312 0.0311
Brugia malayi tailless protein 0.001 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0519 0.0517
Giardia lamblia Hypothetical protein 0.0016 0.0056 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0519 0.0517
Entamoeba histolytica cysteine proteinase, putative 0.0053 0.0325 0.1569
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0105 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0165 0.0794
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.5092 0.5091
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0016 0.0016
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.013 0.1796
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0078 0.1006
Entamoeba histolytica cysteine protease, putative 0.0016 0.0056 0.0265
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.013 0.0624
Onchocerca volvulus 0.0057 0.036 0.2097
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.1295 0.7569
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0511 0.1316
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0053 0.0325 0.0323
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0156 0.0155
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0014 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0464 0.6929
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.008 0.0079
Echinococcus granulosus para nitrobenzyl esterase 0.0229 0.1635 0.1634
Onchocerca volvulus Neuropeptide F receptor homolog 0.0065 0.0416 0.2423
Echinococcus granulosus histone lysine methyltransferase setb 0.0051 0.031 0.0309
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0271 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Loa Loa (eye worm) hypothetical protein 0.0078 0.0511 0.0511
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0011 0.0016 0.0086
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0055 0.0141
Schistosoma mansoni cpg binding protein 0.0063 0.0401 0.0399
Echinococcus granulosus sex peptide receptor 0.0065 0.0416 0.0414
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0086 0.0085
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0055 0.0645
Onchocerca volvulus 0.0053 0.0325 0.189
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0511 0.131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0085
Trypanosoma cruzi cysteine peptidase, putative 0.0031 0.0165 0.0757
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0214 0.0213
Brugia malayi G protein-coupled receptor 0.0065 0.0416 0.0414
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0161 0.042
Echinococcus multilocularis cathepsin L 0.0031 0.0165 0.0163
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.018 0.0811
Schistosoma mansoni survival motor neuron protein 0.0054 0.0332 0.033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.031 0.0309
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0014 0.0012
Brugia malayi putative neuropeptide receptor 0.0065 0.0416 0.0414
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.008
Brugia malayi MH1 domain containing protein 0.0025 0.0117 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0133 0.0133
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.3794 1
Plasmodium falciparum thioredoxin reductase 0.0016 0.0055 0.0141
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Trypanosoma brucei cysteine peptidase C (CPC) 0.0098 0.0664 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0214 0.1001
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.025 0.0654
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0098 0.0664 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0511 0.1342
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0055 0.0645
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.0325 0.0323
Plasmodium vivax vivapain-2 0.0053 0.0325 0.0818
Schistosoma mansoni adenoreceptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus multilocularis BC026374 protein (S09 family) 0.0229 0.1635 0.1634
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.013 0.0309
Brugia malayi MH2 domain containing protein 0.0011 0.0016 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.013 0.0309
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0464 0.1365
Loa Loa (eye worm) hypothetical protein 0.0071 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.013 0.0309
Schistosoma mansoni nuclear receptor 0.001 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Onchocerca volvulus 0.0053 0.0325 0.189
Schistosoma mansoni dep domain containing protein 0.0009 0.0001 0.0000059572
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0065 0.0416 0.0416
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0055 0.0209
Echinococcus granulosus fmrfamide receptor 0.0065 0.0416 0.0414
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0271 0.027
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0006 0.0005
Echinococcus granulosus intermediate filament protein 0.0027 0.0133 0.0131
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0229 0.1635 0.1634
Brugia malayi intermediate filament protein 0.0027 0.0133 0.0131
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0031 0.0165 0.0163
Trypanosoma brucei unspecified product 0.002 0.008 0.103
Onchocerca volvulus 0.0229 0.1635 0.9559
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0214 0.0562
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Trypanosoma cruzi major cysteine proteinase, putative 0.0016 0.0056 0.0215
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0769 0.2024
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Entamoeba histolytica hypothetical protein 0.0036 0.0199 0.096
Leishmania major importin beta-1 subunit, putative 0.0047 0.0282 0.413
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.013 0.0624
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0305 0.0801
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0072 0.018
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0006 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0014 0.0012
Plasmodium falciparum thioredoxin reductase 0.0047 0.0282 0.074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0056 0.0208
Brugia malayi sulfakinin receptor protein 0.0065 0.0416 0.0414
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0315 0.1505
Schistosoma mansoni importin-beta 2 0.0011 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0001 0.0000059572
Brugia malayi Pre-SET motif family protein 0.0205 0.1458 0.1456
Loa Loa (eye worm) MH2 domain-containing protein 0.0361 0.2619 0.2619
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0271 0.0269
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.008
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0055 0.0202
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Loa Loa (eye worm) beta-lactamase 0.0071 0.0464 0.0464
Echinococcus multilocularis pyruvate kinase 0.0033 0.018 0.0178
Schistosoma mansoni amine GPCR 0.0065 0.0416 0.0414
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Entamoeba histolytica cysteine protease, putative 0.0016 0.0056 0.0265
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0085
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0086 0.0086
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0645
Plasmodium vivax unspecified product 0.0015 0.0043 0.0074
Brugia malayi cathepsin L-like precursor 0.0038 0.0216 0.0214
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0039 0.01
Onchocerca volvulus 0.0065 0.0416 0.2423
Brugia malayi Cathepsin L-like precursor 0.0053 0.0325 0.0323
Schistosoma mansoni growth hormone secretagogue receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis dna polymerase eta 0.002 0.008 0.0078
Brugia malayi MH1 domain containing protein 0.0014 0.0036 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.008 0.103
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0416 0.0416
Schistosoma mansoni smad 0.0025 0.0117 0.0116
Brugia malayi nuclear hormone receptor 0.001 0.0006 0.0005
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0727 0.2162
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0416 0.0414
Echinococcus granulosus zinc finger protein 0.0026 0.013 0.0129
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1342
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus granulosus g-protein coupled receptor 0.0065 0.0416 0.0414
Mycobacterium ulcerans hypothetical protein 0.0071 0.0464 0.1192
Loa Loa (eye worm) melatonin receptor type 1A 0.0065 0.0416 0.0416
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0315 0.0827
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.003 0.0029
Echinococcus granulosus cathepsin L cysteine protease 0.0031 0.0165 0.0163
Brugia malayi Calcitonin receptor-like protein seb-1 0.0249 0.1781 0.1779
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0086 0.0085
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0065 0.0416 0.0414
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0015 0.0013
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0006 0.0005
Echinococcus multilocularis smad 0.0025 0.0117 0.0116
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.0165 0.0794
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0085
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0072 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.206 0.5364
Brugia malayi Cathepsin L-like precursor 0.0015 0.0043 0.0042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0416 0.0414
Schistosoma mansoni Smad4 0.0025 0.0117 0.0116
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0815 0.2122
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0117 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0056 0.0208
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Brugia malayi nuclear receptor NHR-67 0.001 0.0006 0.0005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0041 0.0041
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0315 0.0827
Leishmania major hypothetical protein, conserved 0.0071 0.0464 0.6929
Brugia malayi RE15519p 0.0065 0.0416 0.0414
Trypanosoma cruzi ISWI complex protein 0.0018 0.0068 0.0276
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0065 0.0416 0.0414
Brugia malayi Smad1 0.0025 0.0117 0.0116
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0282 0.028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Schistosoma mansoni pyruvate kinase 0.0033 0.018 0.0178
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.017 0.1197 0.1197
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0271 0.0269
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0014 0.0012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0216
Toxoplasma gondii thioredoxin reductase 0.0047 0.0282 0.0739
Schistosoma mansoni neuropeptide receptor 0.0065 0.0416 0.0414
Schistosoma mansoni cpg binding protein 0.0063 0.0401 0.0399
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0209
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Schistosoma mansoni nuclear hormone receptor 0.001 0.0006 0.0005
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0001 0.0000059572
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0056 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.0165 0.2335
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0416 0.0414
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0055 0.0141
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.013 0.0624
Brugia malayi hypothetical protein 0.0036 0.0199 0.0198
Brugia malayi neuropeptide F receptor 0.0065 0.0416 0.0414
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0016 0.0056 0.0107
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.025 0.062
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0074 0.0074
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0464 0.1365
Echinococcus granulosus lamin dm0 0.0027 0.0133 0.0131
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0078 0.0078
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.008 0.0078
Echinococcus granulosus microtubule associated protein 2 0.0694 0.5092 0.5091
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0105 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Brugia malayi cytochrome P450 0.0011 0.0013 0.0011
Plasmodium vivax unspecified product 0.0031 0.0165 0.0395
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Schistosoma mansoni smad1 5 8 and 0.0025 0.0117 0.0116
Giardia lamblia Encystation-specific protease 0.0016 0.0056 0.0006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0053 0.0325 0.1519
Plasmodium vivax vivapain-1 0.0031 0.0165 0.0395
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0016 0.0056 0.0144
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0416 0.0414
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.008 0.0325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0185 0.052
Echinococcus granulosus tumor protein p63 0.0341 0.247 0.2469
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.008 0.0334
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0185 0.0454
Schistosoma mansoni alpha-1 adrenergic receptor 0.0065 0.0416 0.0414
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0282 0.131
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0305 0.449
Plasmodium vivax SET domain protein, putative 0.003 0.0161 0.0385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0376 0.0988
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0464 0.1192
Trypanosoma brucei pyruvate kinase 1 0.0033 0.018 0.2561
Onchocerca volvulus 0.0026 0.013 0.0751
Schistosoma mansoni cathepsin F (C01 family) 0.0053 0.0325 0.0323
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1316
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0144 0.0142
Brugia malayi Cathepsin L-like precursor 0.0053 0.0325 0.0323
Brugia malayi nuclear receptor NHR-88 0.001 0.0006 0.0005
Giardia lamblia Pyruvate kinase 0.0033 0.018 0.0622
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0086
Schistosoma mansoni lamin 0.0027 0.0133 0.0131
Loa Loa (eye worm) nuclear factor I 0.0014 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0416 0.0414
Brugia malayi Tachykinin-like peptides receptor 99D 0.0065 0.0416 0.0414
Echinococcus granulosus pyruvate kinase 0.0017 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.0045 0.027 0.027
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0416 0.0414
Schistosoma mansoni amine GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Onchocerca volvulus 0.0229 0.1635 0.9559
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3794 1
Echinococcus multilocularis geminin 0.0337 0.2437 0.2435
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Echinococcus multilocularis neuropeptide FF receptor 2 0.0065 0.0416 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0464 0.2246
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Brugia malayi fibroinase precursor 0.0016 0.0056 0.0055
Echinococcus granulosus allatostatin A receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0282 0.1339
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0117 0.0116
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0416 0.0414
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0055 0.0053
Brugia malayi ecdysone receptor 0.001 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0199 0.096
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0376 0.0961
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.018 0.0178
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.013 0.0354
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0056 0.0055
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0056 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Echinococcus granulosus orexin receptor type 2 0.0065 0.0416 0.0414
Mycobacterium ulcerans glutaminase 0.0278 0.2002 0.526
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Trypanosoma brucei protein kinase, putative 0.005 0.0305 0.449
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0312 0.0791
Schistosoma mansoni pyruvate kinase 0.0033 0.018 0.0178
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0079 0.0519 0.0517
Brugia malayi beta-lactamase family protein 0.0071 0.0464 0.0462
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus multilocularis 0.0011 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0006 0.0005
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0305 0.0304
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0416 0.0414
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0065 0.0416 0.0414
Plasmodium falciparum pyruvate kinase 2 0.0017 0.006 0.0155
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.5092 0.5091
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.206 1
Schistosoma mansoni hypothetical protein 0.0816 0.5993 0.5992
Brugia malayi nuclear receptor RXR 0.001 0.0006 0.0005
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.025 0.3637
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0086 0.0085
Onchocerca volvulus 0.001 0.0006 0.0027
Echinococcus granulosus BC026374 protein S09 family 0.0229 0.1635 0.1634
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Schistosoma mansoni histamine h1 receptor 0.0065 0.0416 0.0414
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0416 0.0414
Brugia malayi Serotonin receptor 0.0065 0.0416 0.0414
Mycobacterium ulcerans DNA polymerase IV 0.002 0.008 0.0177
Toxoplasma gondii cathepsin B 0.0098 0.0664 0.1746
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0006 0.0027
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0065 0.0416 0.0414
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0023 0.0021
Giardia lamblia Cathepsin B precursor 0.0016 0.0056 0.0006
Schistosoma mansoni zinc finger protein 0.0018 0.0068 0.0067
Plasmodium falciparum importin beta, putative 0.0058 0.0363 0.0953
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0055 0.0104
Schistosoma mansoni hypothetical protein 0.0079 0.0519 0.0517
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0056 0.0208
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0011 0.0014 0.0014
Plasmodium falciparum serine repeat antigen 3 0.0016 0.0056 0.0144
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0016 0.0056 0.0055
Entamoeba histolytica hypothetical protein 0.0036 0.0199 0.096
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0015 0.0013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0815 0.2429
Schistosoma mansoni hypothetical protein 0.0065 0.0416 0.0414
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.008 0.0203
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0282 0.0814
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Brugia malayi Carboxylesterase family protein 0.0229 0.1635 0.1634
Onchocerca volvulus 0.0233 0.1667 0.9744
Loa Loa (eye worm) hypothetical protein 0.1355 1 1
Entamoeba histolytica cysteine proteinase 2 0.0031 0.0165 0.0794
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0084 0.0082
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.008 0.0078
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Toxoplasma gondii cathepsin CPL 0.0053 0.0325 0.0852
Onchocerca volvulus 0.0229 0.1635 0.9559
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0305 0.0304
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0071 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0214 0.0531
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Loa Loa (eye worm) transcription factor SMAD2 0.0361 0.2619 0.2619
Loa Loa (eye worm) carboxylesterase 0.0229 0.1635 0.1635
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0055 0.0104
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Leishmania major cysteine peptidase A (CPA) 0.0053 0.0325 0.4788
Giardia lamblia Cathepsin B precursor 0.0016 0.0056 0.0006
Echinococcus granulosus importin 5 0.0011 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0262 0.1883 0.1883
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0519 0.0517
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0133 0.0317
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.206 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0031 0.0165 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0016 0.0056 0.0006
Mycobacterium tuberculosis Conserved protein 0.0071 0.0464 0.1365
Giardia lamblia Cathepsin L precursor 0.0016 0.0056 0.0006
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0016 0.0056 0.0144
Brugia malayi Dopamine receptor protein 2 0.0065 0.0416 0.0414
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0156 0.0155
Entamoeba histolytica hypothetical protein 0.0036 0.0199 0.096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0105 0.0105
Echinococcus multilocularis snurportin 1 0.0616 0.4506 0.4505
Leishmania major DNA polymerase kappa, putative 0.002 0.008 0.103
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0973 0.2539
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0065 0.0416 0.0414
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.025 0.0971
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi cruzipain precursor, putative 0.0015 0.0043 0.0151
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0199 0.0198
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0031 0.0085
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Chlamydia trachomatis pyruvate kinase 0.0033 0.018 0.0333
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0464 0.2246
Giardia lamblia Cathepsin L-like protease 0.0016 0.0056 0.0006
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.025 0.0654
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0084 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0027
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0016 0.0056 0.0006
Echinococcus multilocularis pyruvate kinase 0.0026 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0026 0.013 0.013
Loa Loa (eye worm) acetylcholinesterase 1 0.1355 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0086 0.0085
Brugia malayi beta-lactamase family protein 0.0071 0.0464 0.0462
Leishmania major pyruvate kinase 0.0033 0.018 0.2561
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0271 0.0269
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0315 0.4644
Schistosoma mansoni biogenic amine receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0056 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Plasmodium falciparum transportin 0.0011 0.0016 0.0037
Schistosoma mansoni Smad4 0.0011 0.0016 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0376 0.0375
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0065 0.0416 0.0414
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0031 0.0085
Echinococcus granulosus acetylcholinesterase 0.1355 1 1
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.006 0.0155
Brugia malayi Pre-SET motif family protein 0.003 0.0161 0.0159
Brugia malayi G-protein coupled receptor 0.0065 0.0416 0.0414
Schistosoma mansoni ran 0.0042 0.025 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0056 0.0208
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0133 0.0133
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0078 0.0173
Brugia malayi Inositol-1 0.0038 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0048 0.0291 0.0291
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0376 0.0961
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Brugia malayi PHD-finger family protein 0.0033 0.0177 0.0175
Loa Loa (eye worm) hypothetical protein 0.0149 0.1043 0.1043
Onchocerca volvulus 0.0065 0.0416 0.2423
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0014 0.0012
Echinococcus multilocularis allatostatin A receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0325 0.1552
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0014 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0031 0.0085
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0086 0.0085
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0086 0.0085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0086 0.0085
Echinococcus multilocularis cpg binding protein 0.0063 0.0401 0.0399
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0727 0.2162
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0091 0.009
Brugia malayi Importin beta-1 subunit 0.0058 0.0363 0.0361
Giardia lamblia Cathepsin B precursor 0.0098 0.0664 0.3035
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0376 0.11
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0416 0.0414
Brugia malayi MAP kinase sur-1 0.005 0.0305 0.0304
Brugia malayi hypothetical protein 0.001 0.0006 0.0005
Echinococcus granulosus neuropeptide s receptor 0.0065 0.0416 0.0414
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0216 0.1041
Echinococcus granulosus survival motor neuron protein 1 0.0262 0.1883 0.1881
Brugia malayi G protein-coupled receptor F59B2.13 0.0065 0.0416 0.0414
Schistosoma mansoni hypothetical protein 0.0065 0.0416 0.0414
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.018 0.0441
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0616 0.4506 0.4506
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0156 0.0155
Brugia malayi hypothetical protein 0.0262 0.1883 0.1881
Schistosoma mansoni cathepsin S (C01 family) 0.0016 0.0056 0.0055
Echinococcus multilocularis translational activator gcn1 0.0011 0.0016 0.0014
Plasmodium falciparum serine repeat antigen 6 0.0016 0.0056 0.0144
Echinococcus granulosus peptide allatostatin:somatostatin 0.0065 0.0416 0.0414
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0511 0.0509
Plasmodium falciparum serine repeat antigen 9 0.0016 0.0056 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0214 0.3087
Leishmania major hypothetical protein, conserved 0.0011 0.0016 0.0039
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0305 0.1248
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0016 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0464 0.1365
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.013 0.1796
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0229 0.1635 0.1634
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0065 0.0416 0.0414
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0079 0.0519 0.0519
Leishmania major DNA polymerase eta, putative 0.002 0.008 0.103
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0464 0.22
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0085
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0048 0.0047
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.008 0.0334
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0016 0.0056 0.0265
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0282 0.134
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.008 0.0334
Onchocerca volvulus 0.0053 0.0325 0.189
Schistosoma mansoni biogenic amine receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.1458 0.1458
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0089 0.0089
Schistosoma mansoni cpg binding protein 0.0057 0.036 0.0358
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Echinococcus multilocularis cathepsin L cysteine protease 0.0053 0.0325 0.0323
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0229 0.1635 0.7923
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.1781
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0035 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0098 0.0664 0.3176
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0086 0.0085
Leishmania major GTP-binding protein, putative 0.0042 0.025 0.3637
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0055 0.0127
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0016 0.0015
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0214 0.0212
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.025 0.0248
Echinococcus granulosus cpg binding protein 0.0063 0.0401 0.0399
Onchocerca volvulus 0.0065 0.0416 0.2423
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.036 0.036
Leishmania major trypanothione reductase 0.0047 0.0282 0.4133
Onchocerca volvulus 0.0027 0.0133 0.0767
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Echinococcus multilocularis cysteine protease 0.0053 0.0325 0.0323
Brugia malayi Dopamine receptor 0.0065 0.0416 0.0414
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0016 0.0056 0.0265
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0016 0.0037
Plasmodium vivax importin-beta 2, putative 0.0058 0.0363 0.0919
Onchocerca volvulus 0.0053 0.0325 0.189
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0325 0.0325
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0815 0.2429
Onchocerca volvulus 0.0065 0.0416 0.2423
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0085
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0065 0.0416 0.0414
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.3794 1
Schistosoma mansoni Smad4 0.0011 0.0016 0.0015
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0214 0.0212
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0214 0.1001
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0014 0.0012
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0416 0.0414
Giardia lamblia Cathepsin B precursor 0.0016 0.0056 0.0006
Toxoplasma gondii exonuclease III APE 0.0038 0.0214 0.0561
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0282 0.0705
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0006 0.0005
Schistosoma mansoni opsin-like receptor 0.0065 0.0416 0.0414
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0014 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0078 0.0326
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.018 0.1042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0464 0.1186
Brugia malayi cathepsin Z-like cysteine proteinase 0.0016 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0056 0.0208
Leishmania major pyruvate kinase 0.0033 0.018 0.2561
Brugia malayi Nuclear hormone receptor E75 0.001 0.0006 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0416 0.0414
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0055 0.0645
Echinococcus granulosus neuropeptide FF receptor 2 0.0065 0.0416 0.0414
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0727 0.1888
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0464 0.1365
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0011 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0016 0.0056 0.0265
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0018 0.0082
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0055 0.0209
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0209
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.008 0.103
Brugia malayi N-terminal motif family protein 0.0183 0.1295 0.1294
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0055 0.0645
Brugia malayi nuclear receptor NHR-88 0.002 0.0086 0.0085
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0086 0.0496
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Mycobacterium leprae Probable lipase LipE 0.0071 0.0464 0.1192
Schistosoma mansoni nuclear receptor 0.001 0.0006 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.008 0.0204
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0312 0.0906
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0153 0.0153
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0065 0.0416 0.0414
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0214 0.0526
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus granulosus g protein coupled receptor 0.0065 0.0416 0.0414
Echinococcus granulosus g protein coupled receptor 0.0065 0.0416 0.0414
Onchocerca volvulus 0.0065 0.0416 0.2423
Schistosoma mansoni dishevelled 0.0009 0.0001 0.0000059572
Schistosoma mansoni opsin-like receptor 0.0065 0.0416 0.0414
Giardia lamblia DINP protein human, muc B family 0.002 0.008 0.0125
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0011 0.0019 0.009
Brugia malayi kap beta 3 protein 0.0011 0.0016 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0524 0.3825 0.3824
Loa Loa (eye worm) hypothetical protein 0.0083 0.0554 0.0554
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.013 0.1796
Echinococcus granulosus FTZ F1 alpha 0.002 0.0086 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0048 0.0047
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.008 0.0068
Schistosoma mansoni neuropeptide f receptor 76f 0.0065 0.0416 0.0414
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0018 0.0026
Brugia malayi Cathepsin L-like precursor 0.0053 0.0325 0.0323
Entamoeba histolytica cysteine proteinase 1, putative 0.0031 0.0165 0.0794
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0035 0.0336
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0056 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0216 0.0988
Entamoeba histolytica cysteine protease, putative 0.0016 0.0056 0.0265
Brugia malayi hypothetical protein 0.0033 0.018 0.0179
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0055 0.0645
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Schistosoma mansoni smad1 5 8 and 0.0025 0.0117 0.0116
Brugia malayi CXXC zinc finger family protein 0.0057 0.036 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0464 0.0462
Echinococcus granulosus neuropeptide receptor 0.0065 0.0416 0.0414
Schistosoma mansoni neuropeptide receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0214 0.0979
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0464 0.0462
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0014 0.0012
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0006 0.0005
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0065 0.0416 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0085
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0074 0.0073
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0016 0.0015
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.2021 0.202
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.008 0.0334
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.018 0.0504
Echinococcus granulosus acetylcholinesterase 0.1355 1 1
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0511 0.0509
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3794 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0015 0.0013
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.025 0.0248
Echinococcus multilocularis carboxylesterase 5A 0.1355 1 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0016 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Plasmodium vivax serine-repeat antigen (SERA) 0.0016 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.0281 0.2021 0.2021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0086
Echinococcus multilocularis G protein coupled receptor 139 0.0065 0.0416 0.0414
Echinococcus granulosus neuropeptide receptor A26 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Leishmania major cytochrome p450-like protein 0.0019 0.0078 0.1006
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) inositol-1 0.0038 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0085
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0023 0.0021
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0085
Giardia lamblia Hypothetical protein 0.0016 0.0056 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0209
Echinococcus granulosus pyruvate kinase 0.0033 0.018 0.0178
Brugia malayi Serotonin receptor 0.0065 0.0416 0.0414
Onchocerca volvulus 0.0065 0.0416 0.2423
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0117 0.0117
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0089 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0464 0.22
Schistosoma mansoni hypothetical protein 0.0054 0.0332 0.033
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0214 0.1035
Loa Loa (eye worm) carboxylesterase 0.1355 1 1
Loa Loa (eye worm) RecQ helicase 0.0021 0.0091 0.0091
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0016 0.0056 0.0107
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0065 0.0416 0.0414
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0053 0.0325 0.0852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0282 0.028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0031 0.0085
Brugia malayi nuclear hormone receptor 0.002 0.0086 0.0085
Echinococcus granulosus dro:myosuppressin receptor 0.0065 0.0416 0.0414
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0014 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Brugia malayi Probable ClpP-like protease 0.0078 0.0511 0.0509
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0282 0.131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Echinococcus multilocularis musashi 0.0027 0.0133 0.0131
Echinococcus granulosus neuroligin 0.0229 0.1635 0.1634
Schistosoma mansoni myosin xvIII 0.0065 0.0416 0.0414
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.018 0.083
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.008
Onchocerca volvulus 0.0065 0.0416 0.2423
Brugia malayi Cathepsin L-like precursor 0.0053 0.0325 0.0323
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0282 0.0282
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0098 0.0664 0.3241
Echinococcus multilocularis pyruvate kinase 0.0033 0.018 0.0178
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0281 0.2021 0.202
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0031 0.0085
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0376 0.0375
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0016 0.0056 0.0056
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0519 0.0517
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0161 0.016
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.008 0.0078
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Onchocerca volvulus 0.001 0.0006 0.0027
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0214 0.0427
Onchocerca volvulus 0.002 0.0086 0.0496
Brugia malayi Cytochrome P450 family protein 0.0029 0.0153 0.0152
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Trichomonas vaginalis esterase, putative 0.0071 0.0464 0.22
Echinococcus multilocularis neuropeptide s receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis muscleblind protein 0.0149 0.1043 0.1041
Schistosoma mansoni glutaminase 0.0278 0.2002 0.2001
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0071 0.0464 0.0464
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0416 0.0414
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0464 0.1192
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0464 0.1365
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0214 0.3087
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0229 0.1635 0.1634
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.018 0.2561
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.008 0.0172
Loa Loa (eye worm) cathepsin B 0.0098 0.0664 0.0664
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0416 0.0414
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0085
Giardia lamblia Cysteine protease 0.0016 0.0056 0.0006
Schistosoma mansoni acetylcholinesterase 0.0229 0.1635 0.1634
Schistosoma mansoni hypothetical protein 0.0079 0.0519 0.0517
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1219
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0065 0.0416 0.2423
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0054 0.0332 0.0332
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0214 0.0533
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0048 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trichomonas vaginalis hypothetical protein 0.0011 0.0016 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0078 0.0326
Plasmodium falciparum serine repeat antigen 8 0.0016 0.0056 0.0144
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0086 0.0085
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0018 0.0023
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0117 0.0116
Brugia malayi cathepsin L-like cysteine proteinase 0.0016 0.0056 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0305 0.1455
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0416 0.0414
Mycobacterium ulcerans pyruvate kinase 0.0033 0.018 0.0441
Onchocerca volvulus 0.0065 0.0416 0.2423
Echinococcus granulosus somatostatin receptor 0.0065 0.0416 0.0414
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.206 1
Entamoeba histolytica cysteine proteinase, putative 0.0053 0.0325 0.1569
Mycobacterium tuberculosis Probable reductase 0.0107 0.0727 0.2162
Brugia malayi beta-lactamase 0.0071 0.0464 0.0462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0056 0.0208
Trypanosoma brucei unspecified product 0.0014 0.0035 0.0336
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0161 0.016
Onchocerca volvulus 0.0229 0.1635 0.9559
Brugia malayi cathepsin L precursor 0.0016 0.0056 0.0055
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0249 0.0248
Brugia malayi Cytochrome P450 family protein 0.0019 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Toxoplasma gondii cathepsin CPC1 0.0016 0.0056 0.0144
Brugia malayi Cathepsin L-like precursor 0.0038 0.0216 0.0214
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0006 0.0006
Brugia malayi latrophilin 2 splice variant baaae 0.017 0.1197 0.1195
Brugia malayi ORL1-like opioid receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0071 0.0464 0.0464
Onchocerca volvulus 0.0071 0.0464 0.2705
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Echinococcus multilocularis neuropeptide receptor A26 0.0065 0.0416 0.0414
Brugia malayi hypothetical protein 0.0149 0.1042 0.1041
Trypanosoma brucei unspecified product 0.0014 0.0035 0.0336
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0065 0.0416 0.0414
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0645
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0065 0.0416 0.0414
Onchocerca volvulus Cathepsin L homolog 0.0053 0.0325 0.189
Trichomonas vaginalis spcc417.12 protein, putative 0.0229 0.1635 0.7923
Echinococcus granulosus dna polymerase kappa 0.002 0.008 0.0078
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.025 0.0248
Schistosoma mansoni hypothetical protein 0.0337 0.2437 0.2435
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0229 0.1635 0.4911
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0043 0.0151
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Plasmodium falciparum cysteine proteinase falcipain 1 0.0031 0.0165 0.0431
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0086 0.0496
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0305 0.1455
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0056 0.0055
Brugia malayi Muscleblind-like protein 0.0149 0.1043 0.1041
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0133 0.0133
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0018 0.0082
Onchocerca volvulus 0.0065 0.0416 0.2423
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Entamoeba histolytica hypothetical protein 0.0047 0.0282 0.1361
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0014 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0086 0.0085
Schistosoma mansoni opsin-like receptor 0.0065 0.0416 0.0414
Schistosoma mansoni hypothetical protein 0.0079 0.0519 0.0517
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0056 0.0208
Schistosoma mansoni cathepsin F (C01 family) 0.0053 0.0325 0.0323
Schistosoma mansoni amine GPCR 0.0065 0.0416 0.0414
Schistosoma mansoni cytochrome P450 0.0011 0.0013 0.0012
Brugia malayi hypothetical protein 0.0051 0.0315 0.0314
Mycobacterium ulcerans DNA polymerase IV 0.002 0.008 0.0177
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0016 0.0016
Echinococcus granulosus pyruvate kinase 0.0033 0.018 0.0178
Loa Loa (eye worm) hypothetical protein 0.0038 0.0216 0.0216
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.008 0.0203
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis ran, putative 0.0042 0.025 0.1154
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0305 0.0304
Echinococcus granulosus translational activator gcn1 0.0011 0.0016 0.0014
Onchocerca volvulus Cathepsin F homolog 0.0053 0.0325 0.189
Trypanosoma cruzi major cysteine proteinase, putative 0.0016 0.0056 0.0215
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.0165 0.2335
Echinococcus multilocularis cathepsin L cysteine protease 0.0053 0.0325 0.0323
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Schistosoma mansoni bromodomain containing protein 0.0078 0.0513 0.0511
Schistosoma mansoni BC026374 protein (S09 family) 0.0229 0.1635 0.1634
Toxoplasma gondii cytochrome p450 superfamily protein 0.0011 0.0013 0.003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.018 0.0178
Trypanosoma brucei trypanothione reductase 0.0047 0.0282 0.4133
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0312 0.0906
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Plasmodium vivax unspecified product 0.0016 0.0056 0.0107
Brugia malayi ecdysteroid receptor 0.002 0.0086 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Giardia lamblia Cathepsin B precursor 0.0098 0.0664 0.3035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Brugia malayi putative neuropeptide receptor NPR1 0.0065 0.0416 0.0414
Plasmodium vivax pyruvate kinase, putative 0.0033 0.018 0.0434
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.006 0.0119
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.052 0.3794 1
Plasmodium falciparum serine repeat antigen 4 0.0016 0.0056 0.0144
Echinococcus multilocularis survival motor neuron protein 1 0.0262 0.1883 0.1881
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0016 0.0056 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Echinococcus multilocularis serotonin receptor 0.0065 0.0416 0.0414
Schistosoma mansoni inositol monophosphatase 0.0038 0.0214 0.0212
Onchocerca volvulus 0.0229 0.1635 0.9559
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0085
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0455 0.3316 1
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0086 0.0085
Onchocerca volvulus 0.0038 0.0216 0.1253
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0229 0.1635 0.1634
Brugia malayi Cathepsin L-like precursor 0.0053 0.0325 0.0323
Brugia malayi hypothetical protein 0.0011 0.0015 0.0013
Echinococcus multilocularis para nitrobenzyl esterase 0.0229 0.1635 0.1634
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.008 0.103
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0464 0.0462
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus multilocularis Smad4 0.0025 0.0117 0.0116
Onchocerca volvulus 0.0239 0.1711 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0416 0.0414
Mycobacterium ulcerans beta-lactamase 0.0071 0.0464 0.1192
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0055 0.0053
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0065 0.0416 0.0414
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0011 0.0014 0.0012
Giardia lamblia Cysteine protease 0.0016 0.0056 0.0006
Echinococcus multilocularis cathepsin L 0.0016 0.0056 0.0055
Loa Loa (eye worm) pyruvate kinase 0.0033 0.018 0.018
Echinococcus granulosus cysteine protease 0.0031 0.0165 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.013 0.0309
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.013 0.0309
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0305 0.0304
Schistosoma mansoni smad1 5 8 and 0.0025 0.0117 0.0116
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0165 0.0163
Brugia malayi G-protein coupled receptor 0.0065 0.0416 0.0414
Schistosoma mansoni cathepsin C 0.0016 0.0056 0.0055
Trypanosoma brucei ISWI complex protein 0.0018 0.0068 0.0853
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0016 0.0056 0.0107
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0511 0.1219
Schistosoma mansoni amine GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0214 0.056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Entamoeba histolytica cysteine protease, putative 0.0053 0.0325 0.1569
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0416 0.0414
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0006 0.0005
Brugia malayi MH2 domain containing protein 0.0025 0.0117 0.0116
Loa Loa (eye worm) glutathione reductase 0.0047 0.0282 0.0282
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0084 0.0082
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0464 0.1365
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0727 0.2162
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0214 0.0427
Onchocerca volvulus 0.0065 0.0416 0.2423
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0086 0.0085
Brugia malayi Bromodomain containing protein 0.0045 0.027 0.0268
Schistosoma mansoni cathepsin B (C01 family) 0.0016 0.0056 0.0055
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.018 0.1042
Mycobacterium ulcerans lipase LipD 0.0071 0.0464 0.1192
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0524 0.3825 0.3825
Schistosoma mansoni inositol monophosphatase 0.0038 0.0214 0.0212
Echinococcus multilocularis cathepsin b 0.0281 0.2021 0.202
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0015 0.0013
Echinococcus multilocularis serotonin receptor 0.0065 0.0416 0.0414
Toxoplasma gondii hypothetical protein 0.0027 0.0133 0.0347
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0149 0.1043 0.1043
Loa Loa (eye worm) DR-78 0.001 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0014 0.0012
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0416 0.0414
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis muscleblind protein 1 0.0149 0.1043 0.1041
Schistosoma mansoni zinc finger protein 0.0026 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0058 0.0363 0.0363
Brugia malayi neuropeptide F receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0214 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0312 0.0311
Echinococcus multilocularis somatostatin receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis transportin 1 0.0011 0.0016 0.0014
Echinococcus granulosus smad 0.0025 0.0117 0.0116
Giardia lamblia Cysteine protease 0.0016 0.0056 0.0006
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0041 0.0039
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0416 0.0414
Brugia malayi glutaminase DH11.1 0.0278 0.2002 0.2001
Brugia malayi nuclear receptor RXR 0.0011 0.0015 0.0013
Echinococcus multilocularis lamin dm0 0.0027 0.0133 0.0131
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0055 0.0202
Onchocerca volvulus 0.0016 0.0056 0.0319
Onchocerca volvulus Cathepsin L homolog 0.0053 0.0325 0.189
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.013 0.0354
Schistosoma mansoni hypothetical protein 0.0023 0.0105 0.0104
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0973 0.2539
Brugia malayi cathepsin Z-like cysteine proteinase 0.0016 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.018 0.018
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0065 0.0416 0.0416
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0016 0.0056 0.0144
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0332 0.033
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0014 0.0012
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0014 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0048 0.0047
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.018 0.0811
Echinococcus granulosus g protein coupled receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Echinococcus multilocularis acetylcholinesterase 0.1355 1 1
Brugia malayi Cathepsin L-like precursor 0.0053 0.0325 0.0323
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0055 0.0053
Brugia malayi MH1 domain containing protein 0.0025 0.0117 0.0116
Toxoplasma gondii ABC1 family protein 0.0071 0.0464 0.1219
Echinococcus granulosus neuropeptide receptor 0.0065 0.0416 0.0414
Echinococcus granulosus 7TM GPCR rhodopsin 0.0065 0.0416 0.0414
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0014
Giardia lamblia Cathepsin L-like protease 0.0016 0.0056 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0072 0.018
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Echinococcus granulosus Smad4 0.0025 0.0117 0.0116
Echinococcus multilocularis zinc finger protein 0.0026 0.013 0.0129
Schistosoma mansoni zinc finger protein 0.001 0.0006 0.0005
Echinococcus granulosus pyruvate kinase 0.0017 0.006 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0014 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0815 0.2429
Onchocerca volvulus 0.0053 0.0325 0.189
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0209
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0305 0.1455
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0055 0.0111
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0105 0.0104
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0055 0.0141
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0325 0.1552
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0376 0.0375
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0031 0.0165 0.0757
Loa Loa (eye worm) hypothetical protein 0.0149 0.1042 0.1042
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0519 0.0517
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0214 0.3096
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0727 0.2162
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0014 0.0014
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0006 0.0005
Leishmania major hypothetical protein, conserved 0.0051 0.0315 0.4644
Plasmodium vivax serine-repeat antigen (SERA) 0.0016 0.0056 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Schistosoma mansoni nuclear hormone receptor 0.001 0.0006 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0416 0.0414
Brugia malayi cathepsin F-like cysteine proteinase 0.0015 0.0043 0.0042
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0016 0.0056 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0026 0.013 0.0128
Schistosoma mansoni importin beta-1 0.0058 0.0363 0.0361
Brugia malayi MH1 domain containing protein 0.0014 0.0036 0.0034
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0016 0.0056 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Entamoeba histolytica Ran family GTPase 0.0042 0.025 0.1206
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0249 0.0248
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0006 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0086 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Echinococcus granulosus importin subunit beta 1 0.0058 0.0363 0.0361
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0376 0.0961
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0016 0.0056 0.0006
Brugia malayi AKH receptor 0.0065 0.0416 0.0414
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0016 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0056 0.0055
Echinococcus granulosus transportin 1 0.0011 0.0016 0.0014
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Echinococcus multilocularis importin 5 0.0011 0.0016 0.0014
Echinococcus granulosus alpha 1A adrenergic receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.008
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Echinococcus granulosus hypothetical protein 0.0065 0.0416 0.0414
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0305 0.449
Schistosoma mansoni cathepsin F (C01 family) 0.0038 0.0216 0.0214
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Echinococcus multilocularis pyruvate kinase 0.0017 0.006 0.0059
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0133 0.0347
Brugia malayi Carboxylesterase family protein 0.0229 0.1635 0.1634
Brugia malayi Carboxylesterase family protein 0.0229 0.1635 0.1634
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0133 0.0311
Loa Loa (eye worm) ctsf protein 0.0053 0.0325 0.0325
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0086 0.0085
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0161 0.0159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0055 0.0209
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0053 0.0325 0.0323
Echinococcus granulosus cathepsin b 0.0281 0.2021 0.202
Schistosoma mansoni hypothetical protein 0.0018 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0053 0.0325 0.1519
Brugia malayi AMP-binding enzyme family protein 0.0026 0.013 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0085
Onchocerca volvulus 0.0027 0.0133 0.0767
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0001 0.0000059572
Onchocerca volvulus 0.0071 0.0464 0.2705
Toxoplasma gondii preprocathepsin c precursor, putative 0.0016 0.0056 0.0144
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0315 0.0827
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1355 1 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0325 0.0325
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0055 0.0111
Echinococcus multilocularis sex peptide receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0031 0.0085
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0091 0.038
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0091 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0056 0.0208
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0085
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0014 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0216 0.0988
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0086 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0464 0.22
Loa Loa (eye worm) hypothetical protein 0.1328 0.9798 0.9798
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0363 0.0952
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.018 0.083
Loa Loa (eye worm) hypothetical protein 0.0026 0.013 0.013
Onchocerca volvulus 0.0071 0.0464 0.2705
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0035 0.0336
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0043 0.0043
Brugia malayi Cathepsin L-like precursor 0.0038 0.0216 0.0214
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0416 0.0414
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0376 0.5582
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0117 0.0116
Trypanosoma cruzi cysteine proteinase, putative 0.0031 0.0165 0.0757
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0056 0.0208
Trypanosoma cruzi ISWI complex protein 0.0018 0.0068 0.0276
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0006 0.0005
Echinococcus granulosus bloom syndrome protein 0.0021 0.0091 0.009
Loa Loa (eye worm) Smad1 0.0025 0.0117 0.0117
Schistosoma mansoni lamin 0.0027 0.0133 0.0131
Mycobacterium tuberculosis Carboxylesterase LipT 0.0229 0.1635 0.4911
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0053 0.0325 0.1519
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0416 0.0414
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.025 0.1179
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Loa Loa (eye worm) hypothetical protein 0.0071 0.0464 0.0464
Echinococcus granulosus tachykinin peptides receptor 99D 0.0065 0.0416 0.0414
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0133 0.0209
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Brugia malayi AMP-binding enzyme family protein 0.0026 0.013 0.0128
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0014
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0056 0.0056
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0337 0.2437 0.2435
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0009 0.0007
Loa Loa (eye worm) glutaminase 0.0278 0.2002 0.2002
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0214 0.0795
Echinococcus granulosus cathepsin b 0.0281 0.2021 0.202
Mycobacterium tuberculosis Conserved protein 0.0071 0.0464 0.1365
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0214 0.0982
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0464 0.0462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0165 0.074
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0105 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.031 0.0309
Echinococcus multilocularis dnaJ subfamily B 0.0816 0.5993 0.5992
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0249 0.1781 0.1779
Giardia lamblia Cathepsin B precursor 0.0098 0.0664 0.3035
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0055 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0085
Mycobacterium tuberculosis Conserved protein 0.0071 0.0464 0.1365
Echinococcus multilocularis tumor protein p63 0.0341 0.247 0.2469
Onchocerca volvulus 0.0065 0.0416 0.2423
Echinococcus granulosus cathepsin L 0.0016 0.0056 0.0055
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0519 0.0519
Brugia malayi RNA, U transporter 1 0.0164 0.1152 0.1151
Entamoeba histolytica HEAT repeat domain containing protein 0.0011 0.0016 0.0068
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.008 0.0334
Schistosoma mansoni amine GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0065 0.0416 0.0416
Giardia lamblia Cathepsin L precursor 0.0016 0.0056 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0214 0.1003
Brugia malayi Carboxylesterase family protein 0.1355 1 1
Schistosoma mansoni nuclear hormone receptor 0.002 0.0086 0.0085
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0048 0.0047
Echinococcus multilocularis g-protein coupled receptor 0.0065 0.0416 0.0414
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0058 0.0057
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0214 0.0979
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0305 0.449
Echinococcus granulosus serotonin receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) cysteine protease 0.0053 0.0325 0.0325
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0006 0.0005
Loa Loa (eye worm) carboxylesterase 0.0229 0.1635 0.1635
Echinococcus granulosus cathepsin l1 0.0053 0.0325 0.0323
Schistosoma mansoni DNA polymerase eta 0.002 0.008 0.0079
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0416 0.0414
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0016 0.0015
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0464 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0014 0.0012
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.008 0.0079
Plasmodium falciparum serine repeat antigen 5 0.0016 0.0056 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.013 0.013
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0416 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0086 0.0085
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0183 0.1295 0.1295
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0305 0.1425
Leishmania major cathepsin L-like protease 0.0053 0.0325 0.4788
Brugia malayi Cytochrome P450 family protein 0.0019 0.0078 0.0077
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0014 0.0012
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0071 0.0464 0.0464
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0006 0.0006
Schistosoma mansoni pyruvate kinase 0.0017 0.006 0.0059
Onchocerca volvulus 0.0065 0.0416 0.2423
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0078 0.0078
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0511 0.1342
Toxoplasma gondii cathepsin CPC2 0.0016 0.0056 0.0144
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0214 0.1032
Plasmodium falciparum acyl-CoA synthetase 0.002 0.008 0.0208
Brugia malayi hypothetical protein 0.0065 0.0416 0.0414
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0006 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0053 0.0325 0.0852
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0014 0.0012
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3794 1
Onchocerca volvulus 0.0053 0.0325 0.189
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0016 0.0056 0.0107
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0199 0.0198
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0006 0.0005
Leishmania major hypothetical protein, conserved 0.0018 0.0068 0.0853
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.008 0.0325
Onchocerca volvulus 0.0065 0.0416 0.2423
Echinococcus granulosus cathepsin L cysteine proteinase 0.0053 0.0325 0.0323
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0055 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0016 0.0056 0.0208
Loa Loa (eye worm) hypothetical protein 0.0051 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0214 0.3096
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0464 0.22
Trypanosoma cruzi cysteine protease, putative 0.0031 0.0165 0.0757
Brugia malayi glutathione reductase 0.0047 0.0282 0.028
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0091 0.009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0249 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Brugia malayi conserved hypotetical protein 0.001 0.0006 0.0005
Plasmodium falciparum cysteine proteinase falcipain 3 0.0053 0.0325 0.0852
Loa Loa (eye worm) cytochrome P450 0.0011 0.0013 0.0013
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.008 0.103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0017 0.006 0.006
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0006 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0315 0.0793
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.008 0.0178
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0133 0.0131
Brugia malayi Dopamine receptor protein 1 0.1328 0.9798 0.9798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0056 0.0208
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0199 0.0198
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0016 0.0056 0.0208
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0363 0.5375
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0098 0.0664 0.0662
Schistosoma mansoni intermediate filament proteins 0.0027 0.0133 0.0131
Schistosoma mansoni coup transcription factor 0.002 0.0086 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0056 0.0055
Plasmodium vivax vivapain-3 0.0031 0.0165 0.0395
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0086
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Onchocerca volvulus 0.0149 0.1042 0.6087
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.2021 0.202
Schistosoma mansoni dishevelled 0.0009 0.0001 0.0000059572
Schistosoma mansoni hypothetical protein 0.0011 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0065 0.0416 0.0414
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0056 0.0319
Trypanosoma cruzi cysteine proteinase, putative 0.0031 0.0165 0.0757
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.013 0.0309
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) pyruvate kinase 0.0033 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0016
Echinococcus multilocularis acetylcholinesterase 0.1355 1 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0016 0.0056 0.0055
Echinococcus multilocularis pyruvate kinase 0.0017 0.006 0.0059
Brugia malayi Pax transcription factor protein 2 0.0239 0.1711 0.1709
Brugia malayi Nuclear hormone receptor E75 0.001 0.0006 0.0005
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0065 0.0416 0.0414
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.003 0.0029
Echinococcus multilocularis neuroligin 0.0229 0.1635 0.1634
Schistosoma mansoni biogenic amine receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) pax transcription factor protein 2 0.0239 0.1711 0.1711
Echinococcus granulosus geminin 0.0337 0.2437 0.2435
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0214 0.061
Echinococcus multilocularis dna polymerase kappa 0.002 0.008 0.0078
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1667 0.8077
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0055 0.0209
Giardia lamblia Cathepsin B precursor 0.0016 0.0056 0.0006
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0125 0.0863 0.2573
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0519 0.0517
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0055 0.0645
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0214 0.0979
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.013 0.0309
Plasmodium falciparum glutathione reductase 0.0016 0.0055 0.0141
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0727 0.2162
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0325 0.4788
Trichomonas vaginalis helicase, putative 0.0013 0.0031 0.0085
Echinococcus granulosus GPCR family 2 0.0079 0.0519 0.0517
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0416 0.0414
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0086 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0315 0.1505
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0464 0.22
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.008 0.0381
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0016 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.0026 0.0129 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.008 0.103
Loa Loa (eye worm) hypothetical protein 0.0229 0.1635 0.1635
Schistosoma mansoni neuropeptide receptor 0.0065 0.0416 0.0414
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0282 0.131
Brugia malayi Cathepsin L-like cysteine proteinase 0.0038 0.0216 0.0214
Schistosoma mansoni hypothetical protein 0.0036 0.0199 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0056 0.0208
Giardia lamblia Pyruvate kinase 0.0017 0.006 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Echinococcus granulosus cathepsin l cysteine peptidase 0.0053 0.0325 0.0323
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0214 0.1003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0051 0.031 0.0309
Brugia malayi hypothetical protein 0.0011 0.0015 0.0013
Schistosoma mansoni smad 0.0011 0.0016 0.0015
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0464 0.1365
Schistosoma mansoni ap endonuclease 0.0038 0.0214 0.0213
Echinococcus granulosus lamin 0.0027 0.0133 0.0131
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0014 0.0012
Echinococcus granulosus dnaJ subfamily B 0.0816 0.5993 0.5992
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0086 0.0496
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0271 0.027
Loa Loa (eye worm) glutaminase 2 0.0278 0.2002 0.2002
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.018 0.1042
Giardia lamblia Cathepsin L precursor 0.0016 0.0056 0.0006
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3794 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0072 0.0187
Schistosoma mansoni cathepsin s 0.0015 0.0043 0.0042
Giardia lamblia Cathepsin L precursor 0.0016 0.0056 0.0006
Entamoeba histolytica cysteine protease, putative 0.0031 0.0165 0.0794
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0031 0.0165 0.0163
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0325 0.1552
Mycobacterium ulcerans hypothetical protein 0.0026 0.013 0.0309
Echinococcus granulosus cathepsin l1 0.0038 0.0216 0.0214
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0014 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0014 0.0012
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0055 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.206 1
Onchocerca volvulus 0.0053 0.0325 0.189
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0031 0.0085
Echinococcus multilocularis G-protein coupled receptor, putative 0.0065 0.0416 0.0414
Plasmodium falciparum serine repeat antigen 1 0.0016 0.0056 0.0144
Entamoeba histolytica cysteine protease, putative 0.0016 0.0056 0.0265
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0325 0.1552
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0511 0.0509
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0072 0.018
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0016 0.0056 0.0107
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0973 0.2907
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0271 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0056 0.0208
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0229 0.1635 0.4911
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0016 0.0056 0.0208
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0015 0.0043 0.0042
Brugia malayi steroid hormone receptor 0.002 0.0086 0.0085
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0006 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0024 0.0115 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0271 0.027
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0085
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0018 0.0082
Loa Loa (eye worm) pyruvate kinase 0.0033 0.018 0.018
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0074 0.0073
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0325 0.1552
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.1355 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0416 0.0414
Echinococcus granulosus carboxylesterase 5A 0.1355 1 1
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.3794 1
Onchocerca volvulus 0.0065 0.0416 0.2423
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.025 0.1179
Echinococcus granulosus cathepsin L 0.0031 0.0165 0.0163
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0065 0.0416 0.0416
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0305 0.1455
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0015 0.0015
Brugia malayi cathepsin B-like cysteine proteinase 0.0281 0.2021 0.202
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0065 0.0416 0.0414
Mycobacterium ulcerans carboxylesterase, LipT 0.0229 0.1635 0.429
Echinococcus granulosus pyruvate kinase 0.0017 0.006 0.0059
Echinococcus multilocularis cysteine protease 0.0053 0.0325 0.0323
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.2021 0.202
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0229 0.1635 0.1634
Echinococcus multilocularis cathepsin b 0.0281 0.2021 0.202
Brugia malayi MH2 domain containing protein 0.0025 0.0117 0.0116
Echinococcus granulosus snurportin 1 0.0616 0.4506 0.4505
Brugia malayi GnHR receptor homolog 0.0065 0.0416 0.0414
Plasmodium vivax vivapain-2 0.0053 0.0325 0.0818
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0056 0.0208
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0305 0.0304
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0416 0.0414
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0016 0.0056 0.0208
Giardia lamblia Cysteine protease 0.0016 0.0056 0.0006
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0416 0.0414
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0016 0.0016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0065 0.0416 0.0416
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0376 0.0375
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0041 0.0066
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.013 0.0309

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = -5.18 Inhibitory concentration against DOXP reductoisomerase ChEMBL. 15887963

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.