Detailed information for compound 1176448

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 773.952 | Formula: C41H63N3O11
  • H donors: 2 H acceptors: 4 LogP: 4.77 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC[C@H]1OC(=O)[C@H](C)[C@H]2OC/C(=N\OCc3ccccc3)/CCO[C@@]([C@@H]([C@H]2C)O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)(C[C@H](C(=O)[C@@H]([C@@H]2[C@]1(C)OC(=O)N2)C)C)C
  • InChi: 1S/C41H63N3O11/c1-11-31-41(8)35(42-39(48)55-41)25(4)32(45)23(2)20-40(7)36(54-38-33(46)30(44(9)10)19-24(3)52-38)26(5)34(27(6)37(47)53-31)49-22-29(17-18-50-40)43-51-21-28-15-13-12-14-16-28/h12-16,23-27,30-31,33-36,38,46H,11,17-22H2,1-10H3,(H,42,48)/b43-29-/t23-,24-,25+,26+,27-,30+,31-,33-,34+,35-,36-,38+,40-,41-/m1/s1
  • InChiKey: PWDAZEBIOZXQRY-SCKLUERHSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0066 0.0288
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0123 0.0219 0.0896
Brugia malayi Nuclear hormone receptor family member nhr-40 0.005 0.0072 0.0317
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0123 0.0219 0.3209
Brugia malayi prolyl oligopeptidase family protein 0.0083 0.0139 0.0607
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0023 0.0071
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0017 0.0006 0.0086
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0019 0.0082
Schistosoma mansoni ran 0.0042 0.0056 0.0119
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0006 0.0094
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0015 0.0002 0.0029
Brugia malayi nuclear receptor NHR-88 0.005 0.0072 0.0317
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Trichomonas vaginalis set domain proteins, putative 0.1222 0.2442 1
Schistosoma mansoni nocturnin 0.0015 0.0002 0.0002
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0006 0.0094
Echinococcus granulosus lysosomal alpha glucosidase 0.0174 0.0323 0.07
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0076 0.0125 0.0355
Echinococcus multilocularis snurportin 1 0.0609 0.1203 0.1201
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0154 0.0282 0.0614
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0058 0.0238
Onchocerca volvulus Alhambra homolog 0.0028 0.0028 0.0116
Schistosoma mansoni hypothetical protein 0.0148 0.0269 0.0586
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0019 0.0036
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0002 0.0029
Schistosoma mansoni lipoxygenase 0.0084 0.014 0.0303
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0189 0.0774
Trypanosoma brucei prolyl endopeptidase 0.0083 0.0139 0.2032
Echinococcus multilocularis RUN 0.002 0.0011 0.0009
Giardia lamblia GTOR 0.0018 0.0006 0.0203
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0423 0.0827 0.0825
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0063 0.0133
Schistosoma mansoni inositol monophosphatase 0.0043 0.0058 0.0124
Plasmodium vivax vivapain-2 0.0017 0.0005 0.0095
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0123 0.0219 0.0217
Brugia malayi Fli-1 protein 0.0235 0.0445 0.1952
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0023 0.0045
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0076 0.0125 0.5663
Echinococcus multilocularis musashi 0.0135 0.0244 0.0242
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0084
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0125 0.0511
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0019 0.0036
Mycobacterium ulcerans lipase LipD 0.0108 0.0189 0.0577
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0164 0.0353
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0006 0.0012
Onchocerca volvulus 0.0018 0.0008 0.0032
Echinococcus granulosus survival motor neuron protein 1 0.0724 0.1435 0.3127
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0005 0.0003
Schistosoma mansoni smad 0.0026 0.0023 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi hypothetical protein 0.0018 0.0008 0.0034
Onchocerca volvulus 0.0024 0.0019 0.0077
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.0189 0.0644
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0083 0.0139 0.03
Brugia malayi Cytochrome P450 family protein 0.0036 0.0043 0.0189
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.0189 0.0644
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.1451 0.2905 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0023 0.0302
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.002 0.0018
Leishmania major hypothetical protein, conserved 0.0108 0.0189 0.2771
Entamoeba histolytica Ran family GTPase 0.0042 0.0056 0.1003
Echinococcus granulosus ubiquitin specific protease 41 0.0111 0.0195 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Schistosoma mansoni hypothetical protein 0.0045 0.0063 0.0135
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0008 0.0034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Onchocerca volvulus Protein ultraspiracle homolog 0.005 0.0072 0.0296
Brugia malayi MH1 domain containing protein 0.0026 0.0023 0.01
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0717
Onchocerca volvulus Prolyl endopeptidase homolog 0.0083 0.0139 0.0567
Echinococcus multilocularis GPCR, family 2 0.0078 0.0129 0.0127
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0019 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.0245
Schistosoma mansoni GTP-binding protein alpha subunit 0.0018 0.0008 0.0014
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0125 0.0511
Schistosoma mansoni GTP-binding protein alpha subunit 0.0018 0.0008 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0423 0.0827 0.18
Giardia lamblia Alanyl dipeptidyl peptidase 0.0083 0.0139 0.6297
Schistosoma mansoni hypothetical protein 0.0664 0.1314 0.2865
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0072 0.0153
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.005 0.0072 0.0317
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.0189 0.0644
Onchocerca volvulus 0.0148 0.0269 0.1104
Onchocerca volvulus 0.0017 0.0005 0.0019
Echinococcus granulosus histone lysine methyltransferase setb 0.0154 0.0282 0.0612
Schistosoma mansoni nuclear receptor 0.0024 0.0019 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0066 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.008
Schistosoma mansoni ap endonuclease 0.0076 0.0125 0.027
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0023 0.0071
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0117 0.0513
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0018 0.0008 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0076 0.0125 0.183
Loa Loa (eye worm) transcription factor SMAD2 0.0376 0.0732 0.3206
Loa Loa (eye worm) hypothetical protein 0.0057 0.0086 0.0378
Brugia malayi Calcitonin receptor-like protein seb-1 0.0247 0.047 0.2058
Onchocerca volvulus 0.0101 0.0174 0.0714
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.0189 0.2771
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0219 0.0896
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0129 0.0127
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0386
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0083 0.0139 0.2032
Schistosoma mansoni importin beta-1 0.0057 0.0086 0.0186
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.004 0.0176
Brugia malayi jmjC domain containing protein 0.0034 0.004 0.0176
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0019 0.0017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0423 0.0827 0.0825
Schistosoma mansoni Smad4 0.0026 0.0023 0.0047
Brugia malayi prolyl oligopeptidase family protein 0.1046 0.2085 0.9138
Brugia malayi Cytochrome P450 family protein 0.0104 0.0181 0.0791
Loa Loa (eye worm) prolyl oligopeptidase 0.1046 0.2085 0.9138
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0154 0.0282 0.0614
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0076 0.0125 0.183
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0129 0.0564
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0083 0.0139 0.2032
Onchocerca volvulus 0.0162 0.0299 0.1223
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0066 0.015
Echinococcus multilocularis FTZ F1 alpha 0.005 0.0072 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.005 0.0072 0.0317
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0023 0.0071
Echinococcus granulosus serine protein kinase ATM 0.0024 0.002 0.0039
Schistosoma mansoni smad1 5 8 and 0.0026 0.0023 0.0047
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0066 0.015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0049 0.088
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0049 0.0047
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0123 0.0219 0.3209
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0164 0.0162
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0159 0.0157
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0049 0.0201
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.002 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0075 0.0162
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0023 0.033
Echinococcus multilocularis microtubule associated protein 2 0.0687 0.1359 0.1358
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0005 0.0019
Mycobacterium tuberculosis Conserved protein 0.0108 0.0189 0.0644
Toxoplasma gondii exonuclease III APE 0.0076 0.0125 0.1806
Brugia malayi nuclear receptor RXR 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0072 0.0317
Treponema pallidum exodeoxyribonuclease (exoA) 0.0076 0.0125 1
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0123 0.0219 0.3931
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0111 0.0195 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0139 0.0567
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0002 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.005 0.0072 0.0153
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni polycystin 1-related 0.002 0.0011 0.0022
Brugia malayi beta-lactamase 0.0108 0.0189 0.0828
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0049 0.0718
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.005 0.0072 0.0153
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0006 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0189 0.2771
Plasmodium vivax vivapain-2 0.0017 0.0005 0.0095
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0255 0.0253
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0083 0.0139 0.0567
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.002 0.0288
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0075 0.1104
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0054 0.0052
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0075 0.1078
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.004 0.0085
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0008 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0154 0.0282 0.0614
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0724 0.1435 0.6286
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0123 0.0219 0.0896
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.005 0.0072 0.0317
Brugia malayi Ets-domain containing protein 0.0077 0.0127 0.0558
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0076 0.0125 0.0547
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0029
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0083 0.0139 0.2032
Brugia malayi prolyl oligopeptidase family protein 0.0083 0.0139 0.0607
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.0038
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0056 0.1921
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0006 0.0094
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0049 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0015 0.0002 0.0029
Onchocerca volvulus Bile acid receptor homolog 0.005 0.0072 0.0296
Schistosoma mansoni RAR-like nuclear receptor 0.005 0.0072 0.0155
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0018 0.0008 0.0034
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.0189 0.0644
Mycobacterium ulcerans TetR family transcriptional regulator 0.1451 0.2905 1
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Schistosoma mansoni ap endonuclease 0.0076 0.0125 0.027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0135 0.0244 0.1068
Echinococcus multilocularis ecdysone induced protein 78C 0.005 0.0072 0.007
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0018 0.0008 0.0012
Schistosoma mansoni cytochrome P450 0.0026 0.0023 0.0047
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0066 0.0964
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0006 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0023 0.0071
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0023 0.0071
Onchocerca volvulus 0.0017 0.0005 0.0019
Onchocerca volvulus 0.0017 0.0005 0.0019
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0005 0.0003
Loa Loa (eye worm) inositol-1 0.0043 0.0058 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-25 0.005 0.0072 0.0317
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Onchocerca volvulus 0.005 0.0072 0.0296
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0066 0.0288
Echinococcus granulosus peregrin 0.0032 0.0035 0.0072
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0076 0.0125 0.183
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.005 0.0072 0.007
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0123 0.0219 0.0475
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Brugia malayi hypothetical protein 0.0724 0.1435 0.6286
Brugia malayi hypothetical protein 0.002 0.0011 0.005
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0008 0.0014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0247 0.047 0.2058
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0247 0.047 0.2058
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0129 0.0564
Brugia malayi hypothetical protein 0.0101 0.0176 0.0771
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0129 0.0564
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0075 0.016
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0028 0.0935
Trypanosoma cruzi prolyl endopeptidase 0.0083 0.0139 0.2032
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.0189 0.0577
Schistosoma mansoni alpha-glucosidase 0.015 0.0274 0.0595
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0195 0.2861
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0076 0.0125 0.183
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0002 0.0029
Loa Loa (eye worm) Smad1 0.0026 0.0023 0.01
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0189 0.6668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0023 0.0045
Echinococcus multilocularis cysteine protease 0.0017 0.0005 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Onchocerca volvulus 0.0108 0.0189 0.0774
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0154 0.0282 0.4124
Onchocerca volvulus 0.0017 0.0005 0.0019
Schistosoma mansoni smad1 5 8 and 0.0026 0.0023 0.0047
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi TAR-binding protein 0.02 0.0376 0.1648
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0083 0.0139 0.2008
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0051 0.0049
Leishmania major pantothenate kinase subunit, putative 0.0017 0.0006 0.0086
Loa Loa (eye worm) acetyltransferase 0.014 0.0255 0.1116
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0023 0.0071
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0084
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0066 0.015
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0002 0.0029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0023 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Entamoeba histolytica G protein alpha subunit, putative 0.0018 0.0008 0.0138
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0018 0.0008 0.0034
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.005 0.0072 0.0153
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.005 0.0072 0.0155
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0099 0.1458
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0066 0.015
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0002 0.0036
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0059
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0049 0.0691
Brugia malayi hypothetical protein 0.0119 0.0211 0.0925
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Echinococcus granulosus tumor protein p63 0.1036 0.2066 0.4506
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0103 0.022
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0023 0.0071
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0002 0.0029
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.002 0.0086
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0015 0.0002 0.0029
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0125 0.438
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1046 0.2085 0.854
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0089 0.0391
Onchocerca volvulus 0.0123 0.0219 0.0896
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0005 0.0153
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0054 0.077
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0008 0.0034
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0049 0.0201
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0054 0.0113
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0111 0.0195 0.0193
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0002 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0066 0.015
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0247 0.0534
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Loa Loa (eye worm) hypothetical protein 0.0119 0.0211 0.0925
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0042 0.5
Brugia malayi MH2 domain containing protein 0.0026 0.0023 0.01
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0111 0.0195 0.0423
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0054 0.0235
Loa Loa (eye worm) cysteine protease 0.0017 0.0005 0.002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0072 0.007
Brugia malayi Pre-SET motif family protein 0.0154 0.0282 0.1237
Onchocerca volvulus Huntingtin homolog 0.0119 0.0211 0.0865
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0043 0.0634
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0159 0.0342
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0018 0.0008 0.0034
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0006 0.0028
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0029
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0019 0.0036
Echinococcus granulosus RUN 0.002 0.0011 0.002
Echinococcus multilocularis thyroid hormone receptor alpha 0.005 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.0041 0.0054 0.0235
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0129 0.0277
Loa Loa (eye worm) fibroinase 0.0017 0.0005 0.002
Brugia malayi CCR4 0.0015 0.0002 0.0009
Leishmania major oligopeptidase b 0.0083 0.0139 0.2032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0042 0.1419
Mycobacterium ulcerans hypothetical protein 0.0047 0.0066 0.015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0019 0.0077
Leishmania major hypothetical protein, conserved 0.0101 0.0176 0.2581
Loa Loa (eye worm) RNA binding protein 0.02 0.0376 0.1648
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0006 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0005 0.0008
Schistosoma mansoni thyroid hormone receptor 0.005 0.0072 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.005 0.0072 0.0317
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0064 0.0264
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.0323 0.0321
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0167 0.0361
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Echinococcus granulosus snurportin 1 0.0609 0.1203 0.2621
Loa Loa (eye worm) G protein alpha subunit 3 0.0018 0.0008 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0176 0.2581
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0083 0.0139 0.0567
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0023 0.0021
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.1046
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0083 0.0139 0.0607
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0023 0.0071
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.0323 0.0321
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0111 0.0195 0.0421
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0018 0.0008 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0005 0.0019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0028 0.0059
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0023 0.0071
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0049 0.0103
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0212 0.0459
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0111 0.0195 0.0423
Brugia malayi hypothetical protein 0.0269 0.0514 0.2253
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0005 0.0003
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Echinococcus multilocularis expressed conserved protein 0.009 0.0152 0.015
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0288
Plasmodium falciparum importin beta, putative 0.0057 0.0086 0.4846
Brugia malayi Glycosyl hydrolases family 31 protein 0.0174 0.0323 0.1413
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0018 0.0008 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0129 0.0277
Brugia malayi PHD-finger family protein 0.0028 0.0028 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0024 0.0107
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0049 0.0201
Echinococcus granulosus lamin 0.0135 0.0244 0.0528
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0008 0.0034
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0352 0.0682 0.1486
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0124
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Onchocerca volvulus 0.0154 0.0282 0.1156
Giardia lamblia PHD finger protein 15 0.0028 0.0028 0.1209
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0028 0.0124
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0066 0.0288
Brugia malayi MAP kinase sur-1 0.0052 0.0075 0.033
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0023 0.0071
Brugia malayi intermediate filament protein 0.0135 0.0244 0.1068
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0043 0.0634
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0006 0.0094
Brugia malayi RNA binding protein 0.02 0.0376 0.1648
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0006 0.0094
Onchocerca volvulus 0.0015 0.0002 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0005 0.0019
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0176 0.2559
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0023 0.0071
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0006 0.0004
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0006 0.0094
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0423 0.0827 0.3623
Brugia malayi Nuclear hormone receptor family member nhr-31 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0018 0.0008 0.0034
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0123 0.0219 0.3209
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0019 0.0017
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0054 0.0114
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0176 0.2581
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.0189 0.0644
Brugia malayi Smad1 0.0026 0.0023 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Onchocerca volvulus 0.0108 0.0189 0.0774
Trypanosoma cruzi oligopeptidase b 0.0083 0.0139 0.2032
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0023 0.0071
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0019 0.0038
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.005 0.0072 0.007
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0075 0.1104
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0099 0.1458
Echinococcus multilocularis acylamino acid releasing enzyme 0.0083 0.0139 0.0137
Brugia malayi Intermediate filament tail domain containing protein 0.0135 0.0244 0.1068
Brugia malayi nuclear receptor RXR 0.0026 0.0024 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Brugia malayi photoreceptor-specific nuclear receptor 0.005 0.0072 0.0317
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0018 0.0008 0.0034
Schistosoma mansoni hypothetical protein 0.0026 0.0023 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0164 0.0717
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0019 0.0036
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0111 0.0195 0.3505
Schistosoma mansoni alpha glucosidase 0.0039 0.0049 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0154 0.0282 0.0614
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0006 0.0028
Onchocerca volvulus 0.002 0.0011 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.005
Echinococcus multilocularis protein patched 0.0041 0.0054 0.0052
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0111 0.0195 0.8905
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0006 0.001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.0189 0.0828
Onchocerca volvulus 0.0018 0.0008 0.0032
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0054 0.1868
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1046 0.2085 0.2084
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0423 0.0827 0.3623
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0064 0.0264
Brugia malayi prolyl oligopeptidase family protein 0.0083 0.0139 0.0607
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0023 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0049 0.0718
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.0189 0.0644
Toxoplasma gondii prolyl endopeptidase 0.0083 0.0139 0.2008
Leishmania major endonuclease/exonuclease protein-like protein 0.0015 0.0002 0.0029
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0212 0.021
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Leishmania major cathepsin L-like protease 0.0064 0.0099 0.1458
Onchocerca volvulus 0.0152 0.0278 0.1137
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0056 0.0792
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0083 0.0139 0.0402
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0056 0.0118
Schistosoma mansoni hypothetical protein 0.0664 0.1314 0.2865
Echinococcus granulosus expressed protein 0.0018 0.0008 0.0012
Giardia lamblia Serine peptidase, putative 0.0123 0.0219 1
Echinococcus multilocularis 0.0026 0.0023 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0024 0.0051
Giardia lamblia Thymus-specific serine protease precursor 0.0123 0.0219 1
Schistosoma mansoni thyroid hormone receptor 0.005 0.0072 0.0155
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0018 0.0008 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0111 0.0195 0.0799
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis esterase, putative 0.0108 0.0189 0.0774
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0018 0.0008 0.0012
Brugia malayi MH1 domain containing protein 0.0026 0.0023 0.01
Loa Loa (eye worm) hypothetical protein 0.0169 0.0312 0.1366
Schistosoma mansoni cript-related 0.0015 0.0002 0.0002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0049 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Schistosoma mansoni gabp alpha 0.0077 0.0127 0.0275
Loa Loa (eye worm) hypothetical protein 0.0065 0.0103 0.0449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Brugia malayi Serine carboxypeptidase S28 family protein 0.0123 0.0219 0.0959
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0308
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0051 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0023 0.0071
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0002 0.0029
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0009
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0018 0.0008 0.0014
Loa Loa (eye worm) prolyl oligopeptidase 0.0083 0.0139 0.0607
Loa Loa (eye worm) cytochrome P450 0.0026 0.0023 0.0099
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0255 0.1116
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0255 0.0553
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0609 0.1203 0.5269
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0023 0.0071
Echinococcus multilocularis peregrin 0.0032 0.0035 0.0033
Onchocerca volvulus Putative neutral sphingomyelinase 0.0015 0.0002 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0352 0.0682 1
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0176 0.6206
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0043 0.0189
Schistosoma mansoni inositol monophosphatase 0.0043 0.0058 0.0124
Onchocerca volvulus 0.0017 0.0005 0.0019
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0018 0.0008 0.0034
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0352 0.0682 1
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0015 0.0002 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0015 0.0002 0.0029
Brugia malayi cytochrome P450 0.0026 0.0023 0.0099
Brugia malayi hypothetical protein 0.002 0.0011 0.005
Trypanosoma brucei prolyl oligopeptidase, putative 0.0083 0.0139 0.2032
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.0189 0.0408
Schistosoma mansoni coup transcription factor 0.005 0.0072 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0139 0.2032
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0056 0.0819
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0015 0.0002 0.0036
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0083 0.0139 0.2032
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0002 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0023 0.0071
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.005 0.0072 0.007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.005 0.0072 0.0317
Schistosoma mansoni lipoxygenase 0.0119 0.0212 0.0461
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0018 0.0008 0.0032
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0123 0.0219 0.3931
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0075 0.0073
Plasmodium vivax importin-beta 2, putative 0.0057 0.0086 0.3007
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0018 0.0008 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0154 0.0282 0.028
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0189 0.0774
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.0127 0.0558
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0018 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0111 0.0195 0.0855
Schistosoma mansoni nuclear receptor 0.0024 0.0019 0.0038
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Brugia malayi hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni hypothetical protein 0.029 0.0557 0.1212
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0423 0.0827 0.1802
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0247 0.047 0.2058
Loa Loa (eye worm) fli-1 protein 0.0235 0.0445 0.1952
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi G-protein alpha subunit 0.0018 0.0008 0.0034
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1046 0.2085 0.4547
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0042 0.0137
Onchocerca volvulus 0.0018 0.0008 0.0032
Schistosoma mansoni intermediate filament proteins 0.0135 0.0244 0.0529
Loa Loa (eye worm) hypothetical protein 0.0083 0.0139 0.0607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Echinococcus multilocularis ubiquitin specific protease 41 0.0111 0.0195 0.0193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0423 0.0827 0.1802
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0125 0.7058
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0049 0.088
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.2281 0.4583 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0005 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Echinococcus multilocularis smad 0.0026 0.0023 0.0021
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.004 0.0084
Loa Loa (eye worm) hypothetical protein 0.0063 0.0098 0.0428
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.005 0.0072 0.0153
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0019 0.0038
Brugia malayi beta-lactamase family protein 0.0108 0.0189 0.0828
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Onchocerca volvulus 0.0017 0.0005 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0139 0.487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0154 0.0282 0.1237
Loa Loa (eye worm) ctsf protein 0.0017 0.0005 0.002
Echinococcus granulosus ecdysone induced protein 78C 0.005 0.0072 0.0153
Trichomonas vaginalis ran, putative 0.0042 0.0056 0.0229
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0189 0.0774
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0176 1
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Onchocerca volvulus Huntingtin homolog 0.0119 0.0211 0.0865
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0028 0.0057
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0246 0.0533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.005 0.0072 0.0317
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0058 0.1044
Entamoeba histolytica hypothetical protein 0.0024 0.002 0.0353
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0047 0.0852
Schistosoma mansoni microtubule-associated protein tau 0.0687 0.1359 0.2964
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.005 0.0072 0.007
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0015 0.0002 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0005 0.0068
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0019 0.0082
Echinococcus multilocularis protein dispatched 1 0.0047 0.0065 0.0063
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0176 1
Echinococcus granulosus expressed conserved protein 0.009 0.0152 0.0327
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0006 0.0094
Toxoplasma gondii cathepsin CPL 0.0017 0.0005 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0066 0.1181
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0066 0.0964
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0006 0.0094
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0064 0.0946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0066 0.1181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0058 0.0852
Echinococcus granulosus Smad4 0.0026 0.0023 0.0045
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0023 0.0045
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0076 0.0125 0.0123
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0101 0.0176 0.0771
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.004 0.0038
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0019 0.0082
Brugia malayi hypothetical protein 0.0065 0.0103 0.0453
Brugia malayi Inositol-1 0.0043 0.0058 0.0255
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0006 0.001
Echinococcus granulosus importin subunit beta 1 0.0057 0.0086 0.0184
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0018 0.0008 0.0014
Echinococcus multilocularis tar DNA binding protein 0.02 0.0376 0.0374
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.02 0.0376 0.1648
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.029 0.0557 0.121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0054 0.022
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0054 0.0223
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0018 0.0008 0.0014
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.2281 0.4583 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0043 0.0072
Echinococcus granulosus FTZ F1 alpha 0.005 0.0072 0.0153
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0049 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0002 0.0036
Mycobacterium ulcerans hypothetical protein 0.0108 0.0189 0.0577
Mycobacterium leprae Probable lipase LipE 0.0108 0.0189 0.0577
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1074 0.2142 0.9386
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0066 0.015
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0005 0.0068
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0086 0.1266
Brugia malayi tailless protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trypanosoma brucei RNA editing exonuclease 2 0.0015 0.0002 0.0029
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.0189 0.0187
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0023 0.0021
Brugia malayi nuclear hormone receptor 0.005 0.0072 0.0317
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.005 0.0072 0.0296
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0072 0.0153
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0018 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0024 0.0051
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0083 0.0139 0.2489
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0018 0.0008 0.0034
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0011 0.002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0269 0.1181
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0018 0.0008 0.0014
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0018 0.0008 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0195 0.0799
Brugia malayi ecdysone receptor 0.0024 0.0019 0.0082
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1046 0.2085 0.4549
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0006 0.0094
Leishmania major cathepsin L-like protease 0.0064 0.0099 0.1458
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0009
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0689 0.1364 0.4691
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0002 0.0008
Brugia malayi hypothetical protein 0.0026 0.0024 0.0107
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0269 0.0514 0.2253
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0049 0.0092
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0058 0.0238
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.005 0.0072 0.0155
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.3095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0019 0.0082
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0352 0.0682 1
Schistosoma mansoni synaptojanin 0.0015 0.0002 0.0002
Loa Loa (eye worm) TAR-binding protein 0.02 0.0376 0.1648
Brugia malayi Importin beta-1 subunit 0.0057 0.0086 0.0378
Echinococcus multilocularis expressed protein 0.0018 0.0008 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0002 0.0009
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0195 0.2861
Echinococcus multilocularis lamin 0.0135 0.0244 0.0242
Brugia malayi MH2 domain containing protein 0.0026 0.0023 0.01
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.0188
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0015 0.0002 0.0009
Mycobacterium ulcerans AcrR family transcriptional regulator 0.1451 0.2905 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0058 0.0123
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0005 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-41 0.005 0.0072 0.0317
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.1451 0.2905 1
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0024 0.0107
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.0127 0.0273
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.0278 0.0603
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0352 0.0682 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0049 0.0201
Loa Loa (eye worm) steroid hormone receptor 0.005 0.0072 0.0317
Schistosoma mansoni smad1 5 8 and 0.0026 0.0023 0.0047
Echinococcus multilocularis geminin 0.0664 0.1314 0.1312
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0086 0.124
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0006 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Echinococcus multilocularis tumor protein p63 0.1036 0.2066 0.2065
Brugia malayi jmjC domain containing protein 0.0093 0.0159 0.0695
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Schistosoma mansoni ran 0.0042 0.0056 0.0119
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0028 0.0386
Echinococcus granulosus Dipeptidyl peptidase 9 0.0352 0.0682 0.1484
Brugia malayi RNA, U transporter 1 0.0162 0.0299 0.131
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0075 0.338
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0066 0.0964
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Brugia malayi Ets-domain containing protein 0.0077 0.0127 0.0558
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0023 0.0071
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Brugia malayi RNA recognition motif domain containing protein 0.02 0.0376 0.1648
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0075 0.016
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0056 0.0054
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.002
Toxoplasma gondii ABC1 family protein 0.0108 0.0189 0.275
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Brugia malayi Pre-SET motif family protein 0.1074 0.2142 0.9386
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0042 0.2287
Schistosoma mansoni synaptojanin 0.0015 0.0002 0.0002
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Onchocerca volvulus 0.0047 0.0066 0.0269
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0005 0.0006
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0001 0.0005
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0352 0.0682 1
Echinococcus multilocularis lamin dm0 0.0135 0.0244 0.0242
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0011 0.0009
Schistosoma mansoni transcription factor LCR-F1 0.029 0.0557 0.1212
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0066 0.1181
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0005 0.0019
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0006 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0074 0.012 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0098 0.0428
Onchocerca volvulus 0.0024 0.0019 0.0077
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0083 0.0139 0.03
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0022
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Trypanosoma cruzi oligopeptidase b 0.0083 0.0139 0.2032
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1143 0.2282 1
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0219 0.0896
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Onchocerca volvulus 0.0135 0.0244 0.0998
Brugia malayi hypothetical protein 0.0024 0.0019 0.0082
Entamoeba histolytica hypothetical protein, conserved 0.0083 0.0139 0.2489
Schistosoma mansoni alpha-glucosidase 0.015 0.0274 0.0595
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0423 0.0827 0.18
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0024 0.0107
Schistosoma mansoni neutral sphingomyelinase 0.0015 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0043 0.0189
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0189 0.041
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0029
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0005 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0123 0.0219 0.0959
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0005 0.0003
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0083 0.0139 0.2032
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0123 0.0219 0.0473
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0063 0.0061
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.0245
Echinococcus multilocularis Smad4 0.0026 0.0023 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0023 0.0071
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0023 0.033
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0019 0.0036
Echinococcus granulosus prolyl endopeptidase 0.0083 0.0139 0.0298
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0154 0.0282 0.028
Leishmania major RNA-editing complex protein MP100, putative 0.0015 0.0002 0.0029
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0018 0.0008 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.0072 0.0155
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0015 0.0002 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0189 0.041
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0054 0.0113
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0024 0.0022
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0066 0.022
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0018 0.0008 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0023 0.01
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0174 0.0323 0.1413
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0111 0.0195 0.0193
Loa Loa (eye worm) hypothetical protein 0.0083 0.0139 0.0607
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0189 0.0774
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0019 0.0077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0005 0.002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.005 0.0072 0.0155
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0076 0.0125 0.0423
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.029 0.0557 0.0555
Loa Loa (eye worm) intermediate filament protein 0.0135 0.0244 0.1068
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.005 0.0072 0.0155
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0006 0.0004
Echinococcus multilocularis cysteine protease 0.0017 0.0005 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Trichomonas vaginalis Phospholipase C precursor, putative 0.0015 0.0002 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0066 0.015
Schistosoma mansoni hypothetical protein 0.0169 0.0312 0.0678
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0111 0.0195 0.0855
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.005 0.0072 0.0317
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0075 0.0073
Schistosoma mansoni zinc finger protein 0.0024 0.0019 0.0038
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0076 0.0125 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-14 0.005 0.0072 0.0317
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0011 0.0536
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Entamoeba histolytica prolyl oligopeptidase family protein 0.0083 0.0139 0.2489
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0018 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Leishmania major cathepsin L-like protease 0.0064 0.0099 0.1458
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0023 0.01
Brugia malayi CHE-14 protein 0.0041 0.0054 0.0235
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0123 0.0219 0.3931
Mycobacterium tuberculosis Conserved protein 0.0108 0.0189 0.0644
Brugia malayi MH2 domain containing protein 0.0376 0.0732 0.3206
Schistosoma mansoni survival motor neuron protein 0.0148 0.0269 0.0586
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0006 0.0065
Mycobacterium ulcerans beta-lactamase 0.0108 0.0189 0.0577
Schistosoma mansoni lamin 0.0135 0.0244 0.0529
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0189 0.0774
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0023 0.0071
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0246 0.0244
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.0189 0.0644
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0047 0.2095
Toxoplasma gondii hypothetical protein 0.0083 0.0139 0.2008
Plasmodium vivax SET domain protein, putative 0.0154 0.0282 1
Onchocerca volvulus 0.0017 0.0005 0.0019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.005 0.0072 0.0153
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0018 0.0008 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0005 0.002
Schistosoma mansoni lamin 0.0135 0.0244 0.0529
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Echinococcus granulosus tar DNA binding protein 0.02 0.0376 0.0817
Echinococcus multilocularis prolyl endopeptidase 0.0083 0.0139 0.0137
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0024 0.0049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0423 0.0827 0.1802
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0022
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0038 0.0124
Brugia malayi ecdysteroid receptor 0.005 0.0072 0.0317
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0049 0.0718
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0099 0.1458
Toxoplasma gondii FATC domain-containing protein 0.0024 0.002 0.026
Echinococcus granulosus acylamino acid releasing enzyme 0.0083 0.0139 0.0298
Mycobacterium tuberculosis Conserved protein 0.0108 0.0189 0.0644
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0129 0.0127
Schistosoma mansoni nuclear hormone receptor 0.005 0.0072 0.0155
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0288
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0075 0.1104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0011 0.0332
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0352 0.0682 0.068
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0084
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.2281 0.4583 0.4582
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0111 0.0195 0.0421
Echinococcus granulosus geminin 0.0664 0.1314 0.2863
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0083 0.0139 0.2032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.0189 0.0828
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0164 0.2941
Loa Loa (eye worm) MH2 domain-containing protein 0.0376 0.0732 0.3206
Trypanosoma brucei protein kinase, putative 0.0052 0.0075 0.1104
Brugia malayi follicle stimulating hormone receptor 0.1143 0.2282 1
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Trypanosoma brucei glucosidase, putative 0.0039 0.0049 0.0718
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0099 0.1458
Brugia malayi Nuclear hormone receptor family member nhr-49 0.005 0.0072 0.0317
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0015 0.0002 0.0029
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0015 0.0002 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.0038
Brugia malayi Steroid receptor seven-up type 2 0.005 0.0072 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0117 0.0513
Schistosoma mansoni steroid hormone receptor ad4bp 0.005 0.0072 0.0155
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0018 0.0008 0.0034
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0005 0.0153
Mycobacterium tuberculosis Probable peptidase 0.0083 0.0139 0.047
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0019 0.0017
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Leishmania major cytochrome p450-like protein 0.0026 0.0023 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0019 0.0082
Entamoeba histolytica hypothetical protein 0.0046 0.0064 0.1159
Mycobacterium leprae conserved hypothetical protein 0.0108 0.0189 0.0577
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0066 0.015
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0006 0.0095
Entamoeba histolytica prolyl oligopeptidase family protein 0.0083 0.0139 0.2489
Leishmania major importin beta-1 subunit, putative 0.0046 0.0064 0.0946
Mycobacterium ulcerans transcriptional regulator 0.1451 0.2905 1
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0068
Loa Loa (eye worm) hypothetical protein 0.0162 0.0299 0.1308
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0083 0.0139 0.0402
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.005 0.0072 0.0317
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0352 0.0682 1
Loa Loa (eye worm) hypothetical protein 0.0119 0.0211 0.0925
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0015 0.0002 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.0076 0.0125 0.0547
Brugia malayi conserved hypotetical protein 0.0024 0.0019 0.0082
Schistosoma mansoni hypothetical protein 0.0039 0.0051 0.0108
Leishmania major cytochrome p450-like protein 0.0026 0.0023 0.033
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0006 0.0115
Echinococcus granulosus cathepsin l1 0.0017 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0317
Leishmania major GTP-binding protein, putative 0.0042 0.0056 0.0819
Brugia malayi Doublecortin family protein 0.002 0.0011 0.005
Brugia malayi hypothetical protein 0.029 0.0557 0.2439
Brugia malayi Cytochrome P450 family protein 0.0026 0.0023 0.0099
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.0189 0.0577
Brugia malayi nuclear hormone receptor 0.0024 0.0019 0.0082
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0123 0.0219 0.3189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.005 0.0072 0.0317
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0023 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.002
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0018 0.0008 0.0014
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.005 0.0072 0.0317
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0058 0.0238
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0072 0.1055
Echinococcus granulosus lamin dm0 0.0135 0.0244 0.0528
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0015 0.0002 0.0029
Schistosoma mansoni loxhd1 0.002 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0015 0.0002 0.0036
Brugia malayi hypothetical protein 0.0026 0.0024 0.0107
Brugia malayi nuclear receptor NHR-67 0.0024 0.0019 0.0082
Echinococcus multilocularis survival motor neuron protein 1 0.0724 0.1435 0.1433
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0006 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0099 0.1458
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0042 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.005 0.0072 0.0317
Loa Loa (eye worm) hypothetical protein 0.0135 0.0244 0.1068
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0288
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0083 0.0139 0.03
Brugia malayi prolyl oligopeptidase family protein 0.0352 0.0682 0.2988
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0176 0.2581
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0019 0.0038
Onchocerca volvulus 0.0135 0.0244 0.0998
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0075 0.033
Onchocerca volvulus 0.0022 0.0015 0.0061
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0006 0.0115
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0047 0.2611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Entamoeba histolytica hypothetical protein 0.029 0.0557 1
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.0127 0.0125
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0018 0.0008 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0189 0.2771
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0076 0.0125 0.2242
Loa Loa (eye worm) hypothetical protein 0.0078 0.0129 0.0564
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0056 0.0819
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0006 0.0095
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0066 0.015
Echinococcus granulosus GPCR family 2 0.0078 0.0129 0.0277
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0054 0.0223
Onchocerca volvulus 0.1222 0.2442 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0019 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Brugia malayi Serine protease Z688.6 precursor 0.0123 0.0219 0.0959
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0043 0.0634
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0058 0.0825
Onchocerca volvulus 0.0015 0.0002 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0026
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0049 0.0069 0.0303
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.002
Echinococcus granulosus intermediate filament protein 0.0135 0.0244 0.0528
Brugia malayi steroid hormone receptor 0.005 0.0072 0.0317
Brugia malayi Bromodomain containing protein 0.0032 0.0035 0.0154
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0005 0.0153
Schistosoma mansoni hypothetical protein 0.0078 0.0129 0.0278
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Brugia malayi Serine protease Z688.6 precursor 0.0123 0.0219 0.0959
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0107
Loa Loa (eye worm) hypothetical protein 0.0066 0.0105 0.0458
Brugia malayi Cytochrome P450 family protein 0.0036 0.0043 0.0189
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0058 0.0122
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0083 0.0139 0.047
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0123 0.0219 0.0896
Loa Loa (eye worm) cytochrome P450 family protein 0.0104 0.0181 0.0791
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0019
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0086 0.0084
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0023 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0139 0.2032
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0056 0.2484
Schistosoma mansoni carbon catabolite repressor protein 0.0015 0.0002 0.0002
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0043 0.0189
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0086 0.1266
Giardia lamblia Alanyl dipeptidyl peptidase 0.0083 0.0139 0.6297
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0049 0.0215
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0075 0.1104
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0018 0.0008 0.0034
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0002 0.0009
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0019 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.002 0.004
Leishmania major cytochrome p450-like protein 0.0036 0.0043 0.0634
Plasmodium falciparum phd finger protein, putative 0.0028 0.0028 0.1507
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0083 0.0139 0.03
Echinococcus granulosus smad 0.0026 0.0023 0.0045
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0123 0.0219 0.0896
Schistosoma mansoni patched 1 0.0041 0.0054 0.0115
Plasmodium falciparum peptidase, putative 0.0083 0.0139 0.7848
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0064 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0019
Echinococcus granulosus microtubule associated protein 2 0.0687 0.1359 0.2963
Loa Loa (eye worm) DR-78 0.0024 0.0019 0.0082
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0111 0.0195 0.2861
Brugia malayi latrophilin 2 splice variant baaae 0.0169 0.0312 0.1366
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0075 0.1104
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0088 0.1295
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0023 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.004 0.0085
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0019 0.0082
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0019 0.0036
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0015 0.0002 0.0036
Brugia malayi beta-lactamase family protein 0.0108 0.0189 0.0828
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0152 0.0278 0.1217
Brugia malayi hypothetical protein 0.0162 0.0299 0.1308
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0056 0.0819
Schistosoma mansoni ets-related 0.0235 0.0445 0.097
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0148 0.0271 0.0587
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0002 0.0036
Schistosoma mansoni hypothetical protein 0.0609 0.1203 0.2622
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.005 0.0072 0.0155
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.002
Brugia malayi nuclear receptor NHR-88 0.0024 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0108 0.0189 0.0828
Entamoeba histolytica prolyl oligopeptidase family protein 0.0083 0.0139 0.2489
Brugia malayi Nuclear hormone receptor family member nhr-19 0.005 0.0072 0.0317
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0103 0.0101
Trypanosoma brucei oligopeptidase b 0.0083 0.0139 0.2032
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0018 0.0008 0.0006
Schistosoma mansoni tar DNA-binding protein 0.02 0.0376 0.0818
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0034
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0028 0.0026
Loa Loa (eye worm) doublecortin family protein 0.002 0.0011 0.005
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0018 0.0008 0.0032
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0008 0.0032
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0076 0.0125 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0056
Onchocerca volvulus 0.002 0.0011 0.0046
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0083 0.0139 0.2489
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0023 0.0071
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0075 0.1104
Loa Loa (eye worm) beta-lactamase 0.0108 0.0189 0.0828
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0111 0.0195 0.2861
Schistosoma mansoni retinoic acid receptor RXR 0.005 0.0072 0.0155
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0054 0.077
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0075 0.1104
Onchocerca volvulus 0.0108 0.0189 0.0774

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.