Detailed information for compound 1265215

Basic information

Technical information
  • TDR Targets ID: 1265215
  • Name: (2-oxooxolan-3-yl) 4-(4-fluorophenyl)-4-oxobu tanoate
  • MW: 280.248 | Formula: C14H13FO5
  • H donors: 0 H acceptors: 3 LogP: 1.55 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc(cc1)F)CCC(=O)OC1CCOC1=O
  • InChi: 1S/C14H13FO5/c15-10-3-1-9(2-4-10)11(16)5-6-13(17)20-12-7-8-19-14(12)18/h1-4,12H,5-8H2
  • InChiKey: YQHSHMSWRWZXRN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2-oxotetrahydrofuran-3-yl) 4-(4-fluorophenyl)-4-oxo-butanoate
  • 4-(4-fluorophenyl)-4-oxobutanoic acid (2-oxo-3-tetrahydrofuranyl) ester
  • 4-(4-fluorophenyl)-4-keto-butyric acid (2-ketotetrahydrofuran-3-yl) ester
  • (2-oxooxolan-3-yl) 4-(4-fluorophenyl)-4-oxo-butanoate
  • MLS000057044
  • SMR000062077
  • T0512-8635
  • Oprea1_087064

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0099 0.0311 0.0315
Plasmodium vivax tyrosine kinase-like protein, putative 0.009 0.0252 0.3163
Echinococcus multilocularis heat shock protein 70 0.0053 0.0005 0.0005
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0249 0.1321 0.1321
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0062 0.0066 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-1 0.034 0.1934 0.197
Brugia malayi Protein kinase domain containing protein 0.0165 0.0761 0.0774
Loa Loa (eye worm) hypothetical protein 0.0117 0.0436 0.0442
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0053 0.0005 0.0003
Entamoeba histolytica hypothetical protein, conserved 0.0053 0.0005 0.0021
Loa Loa (eye worm) CAMK protein kinase 0.0079 0.0176 0.0178
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0092 0.0267 0.1541
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0094 0.0278 0.1606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.034 0.1934 0.197
Schistosoma mansoni nuclear hormone receptor 0.0156 0.0699 0.0713
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0053 0.0005 0.0003
Entamoeba histolytica protein kinase, putative 0.0157 0.0707 0.3035
Echinococcus granulosus titin 0.0079 0.0176 0.0176
Entamoeba histolytica aldose reductase, putative 0.0131 0.0528 0.2267
Onchocerca volvulus Tyrosine kinase homolog 0.0585 0.3588 0.3655
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Loa Loa (eye worm) AGC/PKA protein kinase 0.0123 0.0478 0.0485
Loa Loa (eye worm) AGC/NDR protein kinase 0.0166 0.0767 0.078
Loa Loa (eye worm) hypothetical protein 0.0056 0.0021 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0271 0.1567
Entamoeba histolytica cell division protein kinase 2, putative 0.0129 0.0519 0.2226
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Loa Loa (eye worm) hypothetical protein 0.027 0.1467 0.1493
Plasmodium vivax serine/threonine kinase-1, putative 0.0166 0.0765 0.973
Trichomonas vaginalis CK1 family protein kinase 0.0119 0.0447 0.2604
Brugia malayi orphan nuclear receptor NR2E1 0.0156 0.0699 0.0711
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0099 0.0311 0.1934
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0062 0.0066 0.0358
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis CK1 family protein kinase 0.0119 0.0447 0.2604
Echinococcus multilocularis protein kinase 0.0053 0.0005 0.0005
Echinococcus granulosus neuroglian 0.0058 0.004 0.004
Onchocerca volvulus Protein ultraspiracle homolog 0.034 0.1934 0.1968
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Loa Loa (eye worm) TK protein kinase 0.0205 0.1031 0.1049
Onchocerca volvulus 0.0306 0.171 0.1739
Echinococcus granulosus serine:threonine protein kinase 0.0125 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0111 0.0392 0.0398
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Entamoeba histolytica protein kinase domain containing protein 0.0157 0.0707 0.3035
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0249 0.1321 0.1321
Brugia malayi protein-tyrosine kinase 0.0205 0.1031 0.1049
Loa Loa (eye worm) hypothetical protein 0.0107 0.0366 0.0371
Entamoeba histolytica protein kinase, putative 0.009 0.0255 0.1095
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.046 0.2744 0.2744
Echinococcus granulosus raf serine:threonine protein kinase 0.0097 0.03 0.03
Trypanosoma brucei aurora B kinase 0.0157 0.0707 0.4135
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0022 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0038 0.0195
Trypanosoma brucei aldo-keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus multilocularis suppressor of cytokine signaling 7 0.006 0.0051 0.0051
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0099 0.0311 0.1934
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0099 0.0315 0.0319
Onchocerca volvulus Netrin receptor homolog 0.0058 0.0041 0.0036
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0169 0.0786 1
Echinococcus granulosus c src tyrosine kinase 0.0156 0.07 0.07
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0148 0.0641 0.8148
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0156 0.07 0.0713
Echinococcus granulosus serine/threonine protein kinase 0.0179 0.0849 0.0849
Brugia malayi Protein kinase domain containing protein 0.0634 0.3917 0.3991
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0632 0.0644
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0418 0.2463 0.251
Entamoeba histolytica hypothetical protein 0.0074 0.0144 0.0617
Echinococcus granulosus tyrosine protein kinase Fyn 0.0249 0.1321 0.1321
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0215 0.1098 0.1117
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0661 0.3865
Echinococcus multilocularis roundabout 2 0.0146 0.0629 0.0629
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0519 0.0529
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.022 0.1128 0.6611
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.009 0.0255 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0478 0.2786
Brugia malayi C-terminal src kinase protein 1 0.0053 0.0005 0.0003
Brugia malayi bone morphogenetic protein type 1 receptor 0.0053 0.0005 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.034 0.1934 0.1934
Giardia lamblia Kinase, CMGC DYRK 0.0151 0.0661 0.4145
Loa Loa (eye worm) hypothetical protein 0.018 0.0862 0.0876
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1509 0.9809 0.9809
Loa Loa (eye worm) hypothetical protein 0.0146 0.0627 0.0637
Echinococcus multilocularis kinase suppressor of Ras 1 0.0053 0.0005 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0295 0.0295
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0288 0.1588 0.1588
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Entamoeba histolytica protein kinase domain containing protein 0.022 0.1128 0.4839
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0053 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0113 0.0409 0.1757
Schistosoma mansoni suppressor of cytokine signaling 0.006 0.0051 0.0052
Echinococcus multilocularis thyroid hormone receptor alpha 0.034 0.1934 0.1934
Loa Loa (eye worm) TK protein kinase 0.0371 0.2147 0.2187
Echinococcus granulosus retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 5 0.0129 0.0519 0.0519
Plasmodium falciparum calcium-dependent protein kinase 5 0.0111 0.0392 0.4956
Brugia malayi photoreceptor-specific nuclear receptor 0.034 0.1934 0.197
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0634 0.3917 0.3991
Echinococcus granulosus kinase suppressor of Ras 1 0.0053 0.0005 0.0005
Brugia malayi Furin-like cysteine rich region family protein 0.0766 0.4804 0.4896
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0166 0.0765 0.0778
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0572 0.3341
Schistosoma mansoni coup transcription factor 0.034 0.1934 0.1972
Schistosoma mansoni RAR-like nuclear receptor 0.034 0.1934 0.1972
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0177 0.0839 0.0853
Loa Loa (eye worm) hypothetical protein 0.0136 0.0565 0.0574
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis tyrosine kinase 0.0113 0.0409 0.0409
Schistosoma mansoni protein kinase 0.0256 0.1369 0.1395
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0436 0.2583 0.2583
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0249 0.1321 0.1321
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Brugia malayi ADAMTS-like protease 0.0083 0.0205 0.0207
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0217 0.1111 0.1111
Echinococcus granulosus Protein kinase C brain isozyme 0.0253 0.1351 0.1351
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0113 0.0407 0.0407
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0256 0.1369 0.1369
Brugia malayi hypothetical protein 0.0156 0.0699 0.0711
Brugia malayi Protein kinase domain containing protein 0.0215 0.1098 0.1117
Loa Loa (eye worm) oxidoreductase 0.0131 0.0528 0.0537
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0183 0.0882 0.0899
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0093 0.0271 0.1566
Echinococcus multilocularis nervana 2 0.013 0.052 0.052
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0447 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0346 0.1976 0.2014
Echinococcus granulosus epidermal growth factor receptor 0.0548 0.3334 0.3334
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0588 0.3436
Loa Loa (eye worm) TK/FER protein kinase 0.0431 0.2552 0.26
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.046 0.2744 0.2744
Loa Loa (eye worm) TK/Met protein kinase 0.0053 0.0005 0.0003
Plasmodium falciparum serine/threonine protein kinase KIN 0.0099 0.0311 0.3921
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Entamoeba histolytica protein kinase, putative 0.0092 0.0267 0.1144
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.0534 0.0542
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0261 0.1405 0.1405
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0125 0.0486 0.0493
Schistosoma mansoni protein kinase 0.0157 0.0707 0.0721
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0573 0.0573
Echinococcus granulosus dual specificity 0.0151 0.0661 0.0661
Loa Loa (eye worm) hypothetical protein 0.0146 0.0627 0.0637
Schistosoma mansoni tyrosinase precursor 0.0096 0.0294 0.03
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Echinococcus granulosus adam 0.0077 0.0168 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Echinococcus multilocularis SH2 domain containing adapter protein F 0.006 0.0051 0.0051
Echinococcus multilocularis natriuretic peptide receptor 1 0.0053 0.0005 0.0005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0118 0.0442 0.0451
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0117 0.0436 0.2721
Trypanosoma cruzi cdc2-related kinase 1 0.0129 0.0519 0.3245
Echinococcus granulosus tyrosine protein kinase csk 0.0053 0.0005 0.0005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0311 0.1335
Echinococcus granulosus activin receptor type 0.0093 0.0271 0.0271
Trypanosoma cruzi p21-activated kinase 3, putative 0.0062 0.0066 0.0384
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0669 0.4153 0.4233
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0123 0.0478 0.0485
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0582 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0087 0.0236 0.0238
Loa Loa (eye worm) hypothetical protein 0.0146 0.063 0.064
Onchocerca volvulus 0.0156 0.0699 0.0708
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.022 0.1128 0.709
Echinococcus multilocularis tumor protein p63 0.1537 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0099 0.0315 0.0315
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0119 0.0447 0.2793
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0119 0.0447 0.0454
Echinococcus granulosus SH2 motif 0.006 0.0051 0.0051
Schistosoma mansoni tyrosine kinase 0.0261 0.1405 0.1432
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.034 0.1934 0.1934
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0085 0.0222 0.0224
Loa Loa (eye worm) hypothetical protein 0.0059 0.0045 0.0044
Trichomonas vaginalis AGC family protein kinase 0.009 0.0255 0.1474
Echinococcus multilocularis signal transduction protein lnk realted 0.006 0.0051 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.1546 0.1576
Loa Loa (eye worm) hypothetical protein 0.0183 0.0882 0.0897
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.006 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-14 0.034 0.1934 0.197
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Schistosoma mansoni tyrosine kinase 0.0548 0.3334 0.3399
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Echinococcus granulosus myotubularin protein 13 0.0053 0.0005 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.034 0.1934 0.1972
Echinococcus granulosus c-Jun N-terminal kinases 0.0282 0.1546 0.1546
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0389 0.227 0.227
Onchocerca volvulus 0.0056 0.0022 0.0017
Entamoeba histolytica protein kinase 2, putative 0.0169 0.0786 0.3372
Loa Loa (eye worm) CDC7 protein kinase 0.0099 0.0314 0.0318
Loa Loa (eye worm) TK/RYK protein kinase 0.0053 0.0005 0.0003
Echinococcus multilocularis dual specificity 0.022 0.1128 0.1128
Entamoeba histolytica cell division protein kinase 2, putative 0.0129 0.0519 0.2226
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0021 0.0096
Echinococcus granulosus nervana 2 0.013 0.052 0.052
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0094 0.0278 0.1722
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0255 0.026
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0129 0.0519 0.0519
Echinococcus multilocularis integrin linked protein kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 0.0125 0.0486 0.0486
Schistosoma mansoni tyrosine kinase 0.0086 0.0226 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.022 0.1128 0.115
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0211 0.1071 0.109
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0079 0.0181 0.1113
Schistosoma mansoni vam6/vps39 related 0.0117 0.0436 0.0444
Entamoeba histolytica PH domain containing protein kinase, putative 0.0179 0.0849 0.3643
Onchocerca volvulus 0.0113 0.0409 0.0413
Brugia malayi ecdysone receptor 0.0156 0.0699 0.0711
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0123 0.0478 0.2786
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.006 0.0051 0.0052
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.034 0.1934 0.1934
Echinococcus granulosus defective proboscis extension response 0.0087 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Echinococcus granulosus retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0256 0.1369 0.1395
Loa Loa (eye worm) AGC/PKN protein kinase 0.0302 0.1682 0.1713
Echinococcus granulosus mitogen activated protein kinase 14 0.0172 0.0804 0.0804
Brugia malayi Protein kinase domain containing protein 0.0113 0.0409 0.0415
Trypanosoma cruzi Protein kinase B 0.0179 0.0849 0.5331
Echinococcus granulosus tyrosine protein kinase Blk 0.0205 0.1031 0.1031
Echinococcus granulosus casein kinase I gamma 0.0165 0.0761 0.0761
Giardia lamblia Kinase, CMGC MAPK 0.0093 0.0271 0.1681
Echinococcus multilocularis cyclin dependent kinase 1 0.0129 0.0519 0.0519
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0166 0.0767 0.0767
Giardia lamblia Kinase, STE STE20 0.0094 0.0278 0.1722
Echinococcus granulosus Immunoglobulin 0.0087 0.0236 0.0236
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0131 0.0528 0.0537
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0767 0.0782
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.034 0.1934 0.1972
Echinococcus granulosus ecdysone induced protein 78C 0.034 0.1934 0.1934
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0143 0.0146
Schistosoma mansoni nck2/grb4 0.0103 0.0341 0.0348
Entamoeba histolytica aldose reductase, putative 0.0131 0.0528 0.2267
Echinococcus granulosus tensin C1 domain containing phosphatase 0.006 0.0051 0.0051
Schistosoma mansoni nephrin 0.0058 0.004 0.0041
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0131 0.0528 0.0537
Leishmania major protein kinase, putative 0.0093 0.0271 0.168
Loa Loa (eye worm) TK protein kinase 0.0053 0.0005 0.0003
Echinococcus granulosus Glutaredoxin protein 5 0.013 0.052 0.052
Giardia lamblia Kinase, AGC PKA 0.0123 0.0478 0.2987
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Leishmania major protein kinase A catalytic subunit isoform 2 0.0123 0.0478 0.2987
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Schistosoma mansoni hypothetical protein 0.0074 0.0144 0.0146
Loa Loa (eye worm) AGC/PKG protein kinase 0.0146 0.063 0.0641
Echinococcus multilocularis casein kinase I delta 0.0119 0.0447 0.0447
Brugia malayi Serine/threonine-protein kinase SULU 0.0238 0.1249 0.1271
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0256 0.1369 0.1369
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Echinococcus granulosus fibroblast growth factor receptor 4 0.0261 0.1405 0.1405
Entamoeba histolytica protein kinase, putative 0.0079 0.018 0.0773
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Schistosoma mansoni hypothetical protein 0.0107 0.0366 0.0373
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0099 0.0315 0.0321
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Brugia malayi Protein kinase domain containing protein 0.0166 0.0767 0.078
Brugia malayi Protein kinase domain containing protein 0.0207 0.1041 0.106
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.014 0.0588 0.3685
Loa Loa (eye worm) hypothetical protein 0.0058 0.004 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0169 0.0786 0.0786
Entamoeba histolytica protein kinase , putative 0.0157 0.0707 0.3035
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0157 0.0707 0.8993
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Entamoeba histolytica receptor protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis roundabout 2 0.0058 0.004 0.004
Echinococcus multilocularis tyrosine protein kinase csk 0.0053 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Giardia lamblia Kinase, CK1 Casein kinase 0.0119 0.0447 0.2793
Trypanosoma brucei prostaglandin f synthase 0.0131 0.0528 0.3082
Schistosoma mansoni protein kinase 0.0093 0.0271 0.0276
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0053 0.0005 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0661 0.3865
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.004 0.0038
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0157 0.0703 0.0703
Echinococcus granulosus tensin 0.006 0.0051 0.0051
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0087 0.0234 0.0236
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0478 0.0487
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0129 0.0519 0.3245
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.03 0.0306
Echinococcus granulosus ephrin type A receptor 4 A 0.012 0.0457 0.0457
Brugia malayi tailless protein 0.0156 0.0699 0.0711
Echinococcus multilocularis epidermal growth factor receptor 0.0766 0.4804 0.4804
Loa Loa (eye worm) hypothetical protein 0.0087 0.0236 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.1682 0.1715
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0156 0.0699 0.0708
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0632 0.0644
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0143 0.0146
Plasmodium vivax calcium-dependent protein kinase, putative 0.0111 0.0392 0.4956
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0151 0.0661 0.4014
Brugia malayi Protein-tyrosine phosphatase containing protein 0.006 0.0051 0.005
Echinococcus multilocularis neuroglian 0.0058 0.004 0.004
Schistosoma mansoni zinc finger protein 0.0156 0.0699 0.0713
Brugia malayi nuclear receptor NHR-88 0.0156 0.0699 0.0711
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0767 0.4486
Echinococcus multilocularis casein kinase I alpha 0.0119 0.0447 0.0447
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Echinococcus multilocularis aldo keto reductase 0.0131 0.0528 0.0528
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0143 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0478 0.0487
Giardia lamblia Kinase, CMGC GSK 0.014 0.0588 0.3685
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0217 0.1111 0.113
Echinococcus granulosus integrin linked protein kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0126 0.0493 0.0493
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0027 0.0118
Brugia malayi Guanylyl cyclase protein 23 0.0053 0.0005 0.0003
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.1562 0.9834
Loa Loa (eye worm) hypothetical protein 0.0312 0.1747 0.1779
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.014 0.0588 0.0588
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0123 0.0478 0.2893
Echinococcus multilocularis tyrosine kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0166 0.0767 0.0767
Loa Loa (eye worm) protein kinase domain-containing protein 0.0053 0.0005 0.0003
Schistosoma mansoni hypothetical protein 0.0164 0.0749 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.1249 0.1273
Toxoplasma gondii NEK kinase 0.0058 0.0038 0.0202
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0156 0.0699 0.0699
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.022 0.1128 0.709
Echinococcus multilocularis serine threonine protein kinase 0.0209 0.1056 0.1056
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0349 0.1999 0.2036
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0156 0.0699 0.0699
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0305 0.0311
Echinococcus multilocularis activated cdc42 kinase 1 0.0053 0.0005 0.0005
Entamoeba histolytica SH2 domain containing protein 0.006 0.0051 0.022
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus multilocularis protein KINase family member (kin 25) 0.0053 0.0005 0.0005
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.022 0.1128 0.1148
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Giardia lamblia Kinase, AGC PKA 0.0169 0.0786 0.4932
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0166 0.0767 0.078
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0123 0.0478 0.6057
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0172 0.0804 0.5043
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Brugia malayi hypothetical protein 0.006 0.0051 0.005
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Echinococcus multilocularis serine:threonine protein kinase N2 0.0166 0.0767 0.0767
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Echinococcus granulosus tyrosine protein kinase Srms 0.0541 0.3288 0.3288
Echinococcus multilocularis 0.0165 0.0761 0.0761
Brugia malayi nuclear hormone receptor family member odr-7 0.0156 0.0699 0.0711
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0231 0.1205 0.1205
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0378 0.2193 0.2234
Entamoeba histolytica protein kinase, putative 0.0145 0.0626 0.2687
Schistosoma mansoni nuclear hormone receptor 0.034 0.1934 0.1972
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Echinococcus multilocularis geminin 0.0164 0.0749 0.0749
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0079 0.018 0.018
Echinococcus granulosus protein kinase shaggy 0.014 0.0588 0.0588
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0761 0.0776
Echinococcus multilocularis FTZ F1 alpha 0.034 0.1934 0.1934
Onchocerca volvulus 0.0113 0.0409 0.0413
Echinococcus multilocularis protein kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis roundabout 2 0.0058 0.004 0.004
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0053 0.0005 0.0005
Onchocerca volvulus 0.0156 0.0699 0.0708
Schistosoma mansoni pol-related 0.0131 0.0528 0.0539
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0151 0.0661 0.4145
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Echinococcus multilocularis tyrosine protein kinase HCK 0.0145 0.0626 0.0626
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0166 0.0765 0.4474
Trypanosoma brucei Casein kinase II 0.011 0.0387 0.2249
Plasmodium falciparum cGMP-dependent protein kinase 0.0146 0.063 0.8008
Loa Loa (eye worm) AGC/PKA protein kinase 0.0123 0.0478 0.0485
Leishmania major serine/threonine-protein kinase, putative 0.0058 0.0038 0.0209
Plasmodium vivax protein kinase Crk2 0.0129 0.0519 0.658
Loa Loa (eye worm) STAT protein 0.006 0.0051 0.005
Schistosoma mansoni cpg binding protein 0.0056 0.0022 0.0022
Echinococcus multilocularis tyrosine protein kinase 0.0305 0.1698 0.1698
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0104 0.0346 0.0353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.034 0.1934 0.197
Loa Loa (eye worm) hypothetical protein 0.015 0.0655 0.0666
Brugia malayi Immunoglobulin I-set domain containing protein 0.0284 0.1558 0.1587
Brugia malayi Variant SH3 domain containing protein 0.0103 0.0341 0.0346
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Trypanosoma cruzi cdc2-related kinase 3 0.0129 0.0519 0.3245
Echinococcus granulosus hypothetical protein 0.0127 0.0499 0.0499
Onchocerca volvulus Serine\/threonine kinase homolog 0.0177 0.0839 0.085
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1509 0.9809 1
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0128 0.0507 0.0514
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0129 0.0519 0.0527
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0058 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0517 0.0527
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0111 0.0392 0.0398
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0183 0.0882 0.0897
Brugia malayi Nuclear hormone receptor family member nhr-3 0.034 0.1934 0.197
Brugia malayi Protein kinase domain 0.0095 0.0287 0.0291
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0249 0.1321 0.1321
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0066 0.0067
Toxoplasma gondii CMGC kinase, CK2 family 0.011 0.0387 0.2335
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0093 0.0271 0.1681
Trichomonas vaginalis STE family protein kinase 0.0095 0.0287 0.1662
Echinococcus multilocularis mitogen activated protein kinase 3 0.0093 0.0271 0.0271
Echinococcus granulosus activated cdc42 kinase 1 0.0053 0.0005 0.0005
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.034 0.1934 0.1934
Leishmania major protein kinase, putative 0.0094 0.0278 0.1722
Brugia malayi Fes/CIP4 homology domain containing protein 0.0123 0.0473 0.048
Echinococcus granulosus casein kinase I delta 0.0119 0.0447 0.0447
Trypanosoma cruzi polo-like protein kinase, putative 0.0288 0.1588 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0087 0.0234 0.0234
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0077 0.0168 0.0172
Brugia malayi TAR-binding protein 0.0074 0.0143 0.0143
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0076 0.0158 0.0158
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Schistosoma mansoni protein kinase 0.046 0.2744 0.2797
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0157 0.0703 0.0703
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0179 0.0849 0.5331
Entamoeba histolytica protein kinase, putative 0.0157 0.0707 0.3035
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0093 0.0271 0.168
Echinococcus multilocularis mitogen activated protein kinase 11 0.0172 0.0804 0.0804
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1509 0.9809 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0249 0.1321 0.1321
Echinococcus granulosus tyrosine protein kinase csk 0.0053 0.0005 0.0005
Onchocerca volvulus 0.0113 0.0409 0.0413
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0143 0.0143
Loa Loa (eye worm) TK/FAK protein kinase 0.059 0.3621 0.369
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0288 0.1588 1
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0523 0.3171 0.3171
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0095 0.0287 0.0287
Echinococcus granulosus tyrosine protein kinase ABL1 0.0331 0.1874 0.1874
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0352 0.202 0.2057
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0475 0.2847 0.2901
Brugia malayi protein unc-22 0.0079 0.0176 0.0178
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.2308 0.2308
Brugia malayi Variant SH3 domain containing protein 0.0103 0.0341 0.0346
Giardia lamblia Kinase, CMGC SRPK 0.0092 0.0267 0.1653
Entamoeba histolytica cysteine surface protein, putative 0.0053 0.0005 0.0021
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus multilocularis tyrosine protein kinase csk 0.0053 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0311 0.0317
Plasmodium falciparum serine/threonine protein kinase, putative 0.0157 0.0707 0.8993
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus granulosus dnaJ subfamily B 0.0395 0.2308 0.2308
Echinococcus granulosus cGMP dependent protein kinase 1 0.0146 0.063 0.063
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0351
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0249 0.1321 0.1321
Brugia malayi Protein kinase domain containing protein 0.0092 0.0267 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1205 0.1229
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0632 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0436 0.2583 0.2583
Onchocerca volvulus 0.0096 0.0294 0.0295
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Onchocerca volvulus 0.0067 0.0099 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0661 0.3865
Trichomonas vaginalis STE family protein kinase 0.0095 0.0287 0.1662
Echinococcus multilocularis calcium dependent protein kinase 0.0071 0.0126 0.0126
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0058 0.0038 0.0209
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0707 0.0721
Loa Loa (eye worm) TK protein kinase 0.0053 0.0005 0.0003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.034 0.1934 0.1934
Echinococcus multilocularis protein kinase shaggy 0.014 0.0588 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0176 0.083 0.4858
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Trypanosoma brucei polo-like protein kinase 0.0288 0.1588 0.9324
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0117 0.0436 0.0444
Schistosoma mansoni protein kinase 0.0072 0.0134 0.0137
Echinococcus multilocularis calcium activated potassium channel 0.0146 0.0632 0.0632
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0094 0.0278 0.1192
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0243 0.1284 0.1284
Echinococcus granulosus roundabout 2 0.0146 0.0629 0.0629
Echinococcus granulosus Nuclear hormone receptor HR96 0.0156 0.0699 0.0699
Onchocerca volvulus 0.034 0.1934 0.1968
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0111 0.0392 0.4956
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0144 0.0144
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Brugia malayi MAP kinase sur-1 0.0093 0.0271 0.0274
Schistosoma mansoni hypothetical protein 0.0395 0.2308 0.2353
Entamoeba histolytica protein kinase, putative 0.022 0.1128 0.4839
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Echinococcus granulosus thyroid hormone receptor alpha 0.0156 0.0699 0.0699
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Entamoeba histolytica hypothetical protein 0.0054 0.0007 0.003
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0166 0.0765 0.4474
Echinococcus granulosus casein kinase ii subunit alpha 0.011 0.0387 0.0387
Plasmodium falciparum protein serine/threonine kinase-1 0.0166 0.0765 0.973
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.034 0.1934 0.197
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0392 0.2279
Echinococcus multilocularis casein kinase I alpha 0.0119 0.0447 0.0447
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.004 0.0038
Brugia malayi Cam kinase protein 1 0.0111 0.0392 0.0398
Schistosoma mansoni tyrosine kinase 0.0742 0.4644 0.4734
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0157 0.0707 0.3035
Onchocerca volvulus 0.006 0.0051 0.0047
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0282 0.1546 0.1574
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0079 0.018 0.018
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.1562 0.6703
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0099 0.0311 0.1934
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0113 0.0407 0.0407
Entamoeba histolytica protein kinase domain containing protein 0.0151 0.0661 0.2837
Schistosoma mansoni kinase 0.0308 0.1719 0.1752
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis STE family protein kinase 0.0148 0.0641 0.3747
Mycobacterium ulcerans oxidoreductase 0.0131 0.0528 0.7986
Loa Loa (eye worm) hypothetical protein 0.0117 0.0436 0.0442
Echinococcus multilocularis N chimaerin 0.0104 0.0346 0.0346
Brugia malayi Casein kinase II, alpha chain 0.011 0.0387 0.0392
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0271 0.0276
Brugia malayi SRC-1 0.0249 0.1321 0.1345
Echinococcus granulosus nuclear receptor 2DBD gamma 0.034 0.1934 0.1934
Entamoeba histolytica serine/threonine kinase, putative 0.0053 0.0005 0.0021
Brugia malayi conserved hypotetical protein 0.0156 0.0699 0.0711
Loa Loa (eye worm) hypothetical protein 0.0484 0.2905 0.296
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0087 0.0236 0.0236
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Echinococcus granulosus nuclear receptor nhr 48 0.0156 0.0699 0.0699
Echinococcus granulosus calcium dependent protein kinase 0.0071 0.0126 0.0126
Schistosoma mansoni tyrosinase precursor 0.0096 0.0294 0.03
Schistosoma mansoni shc transforming protein 0.006 0.0051 0.0052
Brugia malayi SH2 domain containing protein 0.0113 0.0409 0.0415
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Loa Loa (eye worm) protein kinase domain-containing protein 0.0165 0.0761 0.0774
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.022 0.1128 0.1148
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0111 0.0392 0.2367
Echinococcus multilocularis Immunoglobulin 0.0087 0.0236 0.0236
Loa Loa (eye worm) serine/threonine protein kinase 0.0053 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0096 0.0294 0.0298
Brugia malayi casein kinase I 0.0119 0.0447 0.0454
Brugia malayi hypothetical protein 0.0113 0.0409 0.0415
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Plasmodium vivax unspecified product 0.011 0.0387 0.489
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0249 0.1321 0.1321
Entamoeba histolytica protein kinase, putative 0.0305 0.1703 0.7308
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Schistosoma mansoni aldo-keto reductase 0.0131 0.0528 0.0539
Loa Loa (eye worm) hypothetical protein 0.0096 0.0295 0.0299
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0054 0.0007 0.003
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0183 0.0882 0.0899
Loa Loa (eye worm) TK/ALK protein kinase 0.0301 0.1675 0.1706
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0282 0.1546 0.1546
Echinococcus granulosus mitogen activated protein kinase 0.0093 0.0271 0.0271
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Loa Loa (eye worm) TK protein kinase 0.0145 0.0626 0.0636
Brugia malayi Fibronectin type III domain containing protein 0.0104 0.0346 0.0351
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0111 0.0392 0.4956
Loa Loa (eye worm) AUR protein kinase 0.0157 0.0707 0.0719
Schistosoma mansoni hypothetical protein 0.0117 0.0436 0.0444
Brugia malayi Tyrosine-protein kinase abl-1 0.0239 0.126 0.1282
Brugia malayi Protein kinase domain containing protein 0.0634 0.3917 0.3991
Echinococcus granulosus tyrosine kinase 0.0113 0.0409 0.0409
Entamoeba histolytica protein kinase, putative 0.0305 0.1703 0.7308
Leishmania major protein kinase A catalytic subunit isoform 1 0.0123 0.0478 0.2987
Entamoeba histolytica p21-activated kinase 0.0104 0.035 0.1504
Schistosoma mansoni serine/threonine kinase 0.0166 0.0767 0.0782
Plasmodium falciparum calcium-dependent protein kinase 2 0.0111 0.0392 0.4956
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Loa Loa (eye worm) hypothetical protein 0.0131 0.0528 0.0537
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Echinococcus granulosus protein kinase c epsilon type 0.0211 0.1071 0.1071
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0519 0.3026
Entamoeba histolytica protein kinase, putative 0.0082 0.0197 0.0846
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Echinococcus multilocularis rho associated protein kinase 0.0346 0.1976 0.1976
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Brugia malayi Protein kinase domain containing protein 0.0113 0.0409 0.0415
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0111 0.0392 0.4956
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0311 0.0317
Brugia malayi hypothetical protein 0.0104 0.0346 0.0351
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0253 0.1351 0.1351
Trypanosoma cruzi polo-like protein kinase, putative 0.0288 0.1588 1
Loa Loa (eye worm) hypothetical protein 0.0378 0.2193 0.2234
Echinococcus granulosus protein kinase c iota type 0.0297 0.1647 0.1647
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0104 0.0346 0.0346
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Loa Loa (eye worm) hypothetical protein 0.0501 0.3018 0.3075
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0661 0.0674
Schistosoma mansoni hypothetical protein 0.006 0.0051 0.0052
Echinococcus multilocularis ephrin type A receptor 4 A 0.012 0.0457 0.0457
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0839 0.0855
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0053 0.0005 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0661 0.3865
Echinococcus granulosus neuroglian 0.011 0.0389 0.0389
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0267 0.0272
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0119 0.0447 0.0454
Echinococcus granulosus titin 0.0079 0.0176 0.0176
Schistosoma mansoni tyrosine kinase 0.0494 0.2976 0.3034
Schistosoma mansoni tyrosine kinase 0.0395 0.2307 0.2352
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Echinococcus multilocularis raf serine:threonine protein kinase 0.0097 0.03 0.03
Toxoplasma gondii AGC kinase 0.0296 0.164 1
Echinococcus multilocularis SH2 motif 0.006 0.0051 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0079 0.0176 0.0178
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0238 0.1249 0.1271
Toxoplasma gondii histone lysine methyltransferase SET1 0.0106 0.0357 0.2155
Echinococcus granulosus tyrosine protein kinase 0.0305 0.1698 0.1698
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0062 0.0066 0.0065
Schistosoma mansoni tensin-related 0.006 0.0051 0.0052
Brugia malayi intracellular kinase 0.014 0.0588 0.0598
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0478 0.0487
Loa Loa (eye worm) hypothetical protein 0.0129 0.0518 0.0526
Brugia malayi Protein kinase domain containing protein 0.0129 0.0519 0.0527
Brugia malayi Protein kinase domain containing protein 0.0125 0.0486 0.0493
Brugia malayi hypothetical protein 0.0053 0.0005 0.0003
Entamoeba histolytica tyrosin kinase, putative 0.0057 0.0027 0.0118
Brugia malayi hypothetical protein 0.0183 0.0882 0.0897
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0071 0.0123 0.0124
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0123 0.0478 0.6057
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0156 0.0699 0.0699
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0418 0.2463 0.2463
Schistosoma mansoni titin 0.0079 0.0176 0.018
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Brugia malayi Protein kinase domain containing protein 0.0389 0.227 0.2312
Echinococcus multilocularis SHC transforming protein 3 0.006 0.0051 0.0051
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0096 0.0294 0.0298
Schistosoma mansoni cell adhesion molecule 0.0123 0.0476 0.0485
Trypanosoma cruzi cdc2-related kinase 1 0.0129 0.0519 0.3245
Loa Loa (eye worm) TK protein kinase 0.0053 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.009 0.0253 0.0256
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.004 0.004
Brugia malayi serine/threonine protein kinase 6 0.0157 0.0707 0.0719
Loa Loa (eye worm) hypothetical protein 0.0059 0.0045 0.0044
Brugia malayi RhoGAP domain containing protein 0.0104 0.0346 0.0351
Loa Loa (eye worm) RNA binding protein 0.0074 0.0143 0.0143
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.02 0.0992 0.1009
Echinococcus multilocularis dual specificity protein kinase clk2 0.0166 0.0765 0.0765
Echinococcus multilocularis growth factor receptor bound protein 2 0.0103 0.0341 0.0341
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0084 0.0212 0.0212
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis rac serine:threonine kinase 0.0179 0.0849 0.0849
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Loa Loa (eye worm) TK protein kinase 0.0053 0.0005 0.0003
Entamoeba histolytica hypothetical protein 0.0074 0.0144 0.0617
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Trypanosoma cruzi aldo/keto reductase, putative 0.0131 0.0528 0.3305
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0205 0.1031 0.1031
Loa Loa (eye worm) hypothetical protein 0.0183 0.0882 0.0897
Echinococcus granulosus serine:threonine protein kinase 0.0125 0.0486 0.0486
Trypanosoma brucei cytochrome P450, putative 0.0099 0.0314 0.1819
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0588 0.2525
Echinococcus granulosus SH2 motif 0.006 0.0051 0.0051
Brugia malayi nuclear receptor RXR 0.0183 0.0882 0.0897
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0249 0.1321 0.1321
Loa Loa (eye worm) hypothetical protein 0.0183 0.0882 0.0897
Schistosoma mansoni cell adhesion molecule 0.0058 0.004 0.0041
Echinococcus granulosus expressed protein 0.0092 0.0267 0.0267
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0099 0.0315 0.1896
Loa Loa (eye worm) ShTK domain-containing protein 0.0096 0.0294 0.0298
Trypanosoma brucei protein kinase, putative 0.014 0.0588 0.3436
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0131 0.0528 0.8252
Echinococcus granulosus tyrosine protein kinase Src42A 0.0154 0.0686 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0992 0.1011
Loa Loa (eye worm) hypothetical protein 0.0069 0.0114 0.0114
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.013 0.052 0.052
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0119 0.0447 0.0454
Entamoeba histolytica protein kinase, putative 0.0296 0.164 0.7037
Echinococcus granulosus casein kinase I delta 0.0119 0.0447 0.0447
Schistosoma mansoni serine/threonine-protein kinase 0.0179 0.0849 0.0865
Schistosoma mansoni tyrosine kinase 0.0156 0.07 0.0713
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Echinococcus multilocularis FL cytokine receptor 0.0053 0.0005 0.0005
Brugia malayi RNA binding protein 0.0074 0.0143 0.0143
Schistosoma mansoni protein kinase 0.0389 0.227 0.2314
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0486 0.2831
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.009 0.0255 0.0258
Entamoeba histolytica protein kinase domain containing protein 0.011 0.0387 0.166
Onchocerca volvulus 0.0131 0.0528 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-40 0.034 0.1934 0.197
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Trypanosoma brucei protein kinase, putative 0.0093 0.0271 0.1567
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Toxoplasma gondii histone kinase SNF1, putative 0.0099 0.0311 0.1873
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase csk 0.0053 0.0005 0.0005
Schistosoma mansoni vav2 0.0113 0.041 0.0418
Entamoeba histolytica protein kinase, putative 0.0072 0.0134 0.0576
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0076 0.0158 0.0158
Echinococcus granulosus SH2 domain containing protein 7 0.006 0.0051 0.0051
Echinococcus multilocularis hypothetical protein 0.0107 0.0366 0.0366
Brugia malayi Protein kinase domain containing protein 0.0305 0.1698 0.1729
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.02 0.0992 0.0992
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0104 0.0346 0.0346
Onchocerca volvulus 0.006 0.0051 0.0047
Onchocerca volvulus 0.0113 0.0409 0.0413
Echinococcus granulosus roundabout 2 0.0058 0.004 0.004
Entamoeba histolytica hypothetical protein 0.0398 0.233 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus multilocularis death associated protein kinase 1 0.0894 0.567 0.567
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0311 0.0317
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.034 0.1934 0.1934
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0548 0.3334 0.3334
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0231 0.1205 0.1205
Brugia malayi nuclear hormone receptor 0.034 0.1934 0.197
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.02 0.0992 0.1009
Brugia malayi Protein kinase domain containing protein 0.0301 0.1676 0.1706
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Entamoeba histolytica PH domain containing protein kinase, putative 0.0179 0.0849 0.3643
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0431 0.2552 0.2552
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0177 0.0839 0.0839
Echinococcus multilocularis serine:threonine protein kinase N2 0.0302 0.1682 0.1682
Schistosoma mansoni signal transduction protein lnk-related 0.006 0.0051 0.0052
Onchocerca volvulus 0.0119 0.0447 0.0451
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0092 0.0267 0.1601
Plasmodium falciparum NIMA related kinase 4 0.0058 0.0038 0.0423
Echinococcus granulosus serine:threonine protein kinase N2 0.0302 0.1682 0.1682
Echinococcus multilocularis casein kinase ii subunit alpha 0.011 0.0387 0.0387
Loa Loa (eye worm) AUR protein kinase 0.0157 0.0707 0.0719
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0099
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0111 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Echinococcus multilocularis cyclin dependent kinase 0.0129 0.0519 0.0519
Leishmania major protein kinase, putative 0.0157 0.0707 0.4435
Brugia malayi Tyrosine-protein kinase PR2 0.0053 0.0005 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0707 0.4135
Echinococcus granulosus serine:threonine protein kinase 3 0.0274 0.1493 0.1493
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Echinococcus multilocularis cpg binding protein 0.0059 0.0043 0.0043
Brugia malayi Protein kinase domain containing protein 0.0113 0.0409 0.0415
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.022 0.1128 0.709
Giardia lamblia Aurora kinase 0.0157 0.0707 0.4435
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0005 0.0005
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0053 0.0005 0.0003
Onchocerca volvulus 0.0346 0.1976 0.201
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0058 0.0038 0.0209
Loa Loa (eye worm) hypothetical protein 0.0183 0.0882 0.0897
Echinococcus granulosus tyrosine protein kinase pr2 0.0053 0.0005 0.0005
Brugia malayi ecdysteroid receptor 0.0501 0.3018 0.3075
Schistosoma mansoni hypothetical protein 0.006 0.0051 0.0052
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0146 0.063 0.3825
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0129 0.0519 0.0527
Echinococcus granulosus hypothetical protein 0.006 0.0051 0.0051
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0051 0.005
Echinococcus granulosus aldo keto reductase 0.0131 0.0528 0.0528
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0661 0.3865
Echinococcus multilocularis SH2 motif 0.006 0.0051 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0765 0.078
Schistosoma mansoni rap gtpase-activating protein 0.0117 0.0436 0.0444
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0295 0.0295
Echinococcus multilocularis serine:threonine protein kinase 38 0.0166 0.0767 0.0767
Onchocerca volvulus 0.015 0.0655 0.0663
Loa Loa (eye worm) TK protein kinase 0.0053 0.0005 0.0003
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0144 0.0144
Schistosoma mansoni tyrosine kinase 0.0277 0.1513 0.1542
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Brugia malayi SH2 domain containing protein 0.0431 0.2552 0.26
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0123 0.0478 0.2987
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.013 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0634 0.3917 0.3991
Brugia malayi nuclear hormone receptor 0.0379 0.22 0.2241
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0351
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0519 0.3026
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0183 0.0882 0.0882
Brugia malayi Muscleblind-like protein 0.0146 0.063 0.064
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0166 0.0765 0.4799
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0271 0.1567
Onchocerca volvulus 0.0131 0.0528 0.0534
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0143 0.0143
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0053 0.0005 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0669 0.4153 0.4233
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0131 0.0528 0.3305
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Echinococcus granulosus receptor type guanylyl cyclase 0.0053 0.0005 0.0005
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0166 0.0767 0.0767
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.004 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Plasmodium falciparum casein kinase 2, alpha subunit 0.011 0.0387 0.489
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Onchocerca volvulus 0.006 0.0051 0.0047
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0082 0.0202 0.0203
Schistosoma mansoni protein tyrosine kinase 0.0053 0.0005 0.0005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0111 0.0392 0.0398
Loa Loa (eye worm) hypothetical protein 0.018 0.0862 0.0876
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.006 0.0051 0.0051
Trypanosoma cruzi casein kinase, putative 0.0119 0.0447 0.2793
Schistosoma mansoni cell adhesion molecule 0.0058 0.004 0.0041
Onchocerca volvulus 0.0113 0.0409 0.0413
Echinococcus multilocularis casein kinase I alpha 0.0119 0.0447 0.0447
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0129 0.0519 0.0527
Echinococcus multilocularis mitogen activated protein kinase 0.0093 0.0271 0.0271
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.034 0.1934 0.1934
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.006 0.0051 0.0047
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0126 0.0493 0.0493
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0096 0.0294 0.0298
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.004 0.0038
Schistosoma mansoni GTPase activating protein 0.006 0.0051 0.0052
Brugia malayi Protein kinase domain containing protein 0.0166 0.0765 0.0778
Loa Loa (eye worm) hypothetical protein 0.0088 0.0238 0.024
Brugia malayi angiogenesis inhibito 0.0083 0.0205 0.0207
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0143 0.0146
Brugia malayi Doublecortin family protein 0.0163 0.0745 0.0757
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0051 0.005
Onchocerca volvulus 0.006 0.0051 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.1481 0.1509
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Brugia malayi protein kinase C3,putative 0.017 0.0793 0.0807
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0053 0.0005 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0767 0.4486
Schistosoma mansoni tyrosine kinase 0.0584 0.3579 0.3648
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0156 0.0699 0.0699
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0254 0.1361 0.1361
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0157 0.0707 0.0707
Onchocerca volvulus 0.0131 0.0528 0.0534
Echinococcus multilocularis ecdysone induced protein 78C 0.034 0.1934 0.1934
Trypanosoma cruzi NIMA-related kinase, putative 0.0058 0.0038 0.0209
Schistosoma mansoni steroid hormone receptor ad4bp 0.034 0.1934 0.1972
Echinococcus granulosus tyrosine protein kinase Lyn 0.0288 0.1587 0.1587
Schistosoma mansoni tyrosine kinase 0.0766 0.4804 0.4898
Echinococcus multilocularis aldo keto reductase 0.0131 0.0528 0.0528
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0169 0.0786 0.0786
Echinococcus granulosus insulin receptor 0.0742 0.4644 0.4644
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0053 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0085 0.0221 0.0223
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Onchocerca volvulus 0.0117 0.0436 0.0439
Brugia malayi Protein kinase c protein 2 0.0126 0.0497 0.0505
Schistosoma mansoni protein kinase C mu 0.0233 0.1217 0.124
Schistosoma mansoni tyrosine kinase 0.0271 0.147 0.1498
Echinococcus granulosus FTZ F1 alpha 0.034 0.1934 0.1934
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0111 0.0392 0.0392
Plasmodium vivax serine/threonine protein kinase, putative 0.0092 0.0267 0.3352
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0233 0.1217 0.1238
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Brugia malayi cytokine inducible SH2-containing protein 5 0.006 0.0051 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0274 0.1493 0.1521
Loa Loa (eye worm) hypothetical protein 0.0096 0.0294 0.0298
Entamoeba histolytica serine/threonine kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica PH domain containing protein kinase, putative 0.0133 0.0541 0.2322
Loa Loa (eye worm) CMGC/GSK protein kinase 0.014 0.0588 0.0598
Echinococcus granulosus suppressor of cytokine signaling 6 0.006 0.0051 0.0051
Echinococcus multilocularis SH2 domain containing protein 7 0.006 0.0051 0.0051
Entamoeba histolytica tyrosin kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica hypothetical protein 0.0054 0.0007 0.003
Giardia lamblia Kinase, STE STE20 0.0095 0.0287 0.1783
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0058 0.004 0.0041
Echinococcus multilocularis casein kinase I gamma 0.0165 0.0761 0.0761
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0254 0.1361 0.1361
Brugia malayi Protein kinase domain containing protein 0.0099 0.0314 0.0318
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0053 0.0005 0.0005
Giardia lamblia Kinase, NEK 0.0058 0.0038 0.0209
Loa Loa (eye worm) oxidoreductase 0.0131 0.0528 0.0537
Schistosoma mansoni growth factor receptor-bound protein 0.0105 0.0355 0.0362
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0103 0.0341 0.0346
Loa Loa (eye worm) nuclear receptor NHR-67 0.0156 0.0699 0.0711
Entamoeba histolytica hypothetical protein 0.022 0.1128 0.4839
Brugia malayi Temporarily assigned gene name protein 59 0.0117 0.0436 0.0442
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Onchocerca volvulus 0.0096 0.0294 0.0295
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0131 0.0528 0.3082
Trypanosoma brucei rac serine-threonine kinase, putative 0.0305 0.1703 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0249 0.1321 0.1321
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0055 0.0019 0.0019
Trichomonas vaginalis CK1 family protein kinase 0.0119 0.0447 0.2604
Brugia malayi Protein kinase domain containing protein 0.0742 0.4644 0.4733
Echinococcus multilocularis 0.0127 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0493 0.2871
Brugia malayi Nuclear hormone receptor family member nhr-31 0.034 0.1934 0.197
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Brugia malayi hypothetical protein 0.0117 0.0436 0.0442
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0099 0.0315 0.1958
Echinococcus multilocularis mitogen activated protein kinase 11 0.0172 0.0804 0.0804
Brugia malayi serine/threonine-protein kinase plk-2 0.0288 0.1588 0.1617
Onchocerca volvulus 0.0099 0.0314 0.0315
Loa Loa (eye worm) hypothetical protein 0.0113 0.0409 0.0415
Loa Loa (eye worm) hypothetical protein 0.0251 0.134 0.1364
Brugia malayi nuclear receptor NHR-88 0.034 0.1934 0.197
Trypanosoma cruzi casein kinase II, putative 0.011 0.0387 0.2412
Echinococcus multilocularis dual specificity 0.0151 0.0661 0.0661
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0111 0.0392 0.2367
Loa Loa (eye worm) TK/CSK protein kinase 0.0053 0.0005 0.0003
Brugia malayi hypothetical protein 0.0059 0.0045 0.0044
Schistosoma mansoni tensin 0.006 0.0051 0.0052
Trypanosoma cruzi cdc2-related kinase 3 0.0129 0.0519 0.3245
Brugia malayi ADAM-TS Spacer 1 family protein 0.027 0.1467 0.1493
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0207 0.1041 0.106
Onchocerca volvulus 0.0509 0.3077 0.3133
Echinococcus multilocularis tyrosine protein kinase Srms 0.0205 0.1031 0.1031
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0166 0.0765 0.4799
Entamoeba histolytica hypothetical protein 0.0054 0.0007 0.003
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0582 1
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0094 0.0278 0.1192
Toxoplasma gondii AGC kinase 0.0123 0.0478 0.2893
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0117 0.0436 0.0436
Trypanosoma cruzi aldo-keto reductase 0.0131 0.0528 0.3305
Brugia malayi Stress-activated protein kinase jnk-1 0.0282 0.1546 0.1574
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0183 0.0882 0.0882
Schistosoma mansoni cellular tumor antigen P53 0.0225 0.1162 0.1185
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0053 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0079 0.018 0.018
Giardia lamblia Aldose reductase 0.0131 0.0528 0.3305
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.034 0.1934 0.197
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0151 0.0661 0.0672
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0232 0.1212 0.1234
Echinococcus granulosus calcium activated potassium channel 0.0146 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0189 0.0922 0.0938
Echinococcus multilocularis receptor type guanylyl cyclase 0.0053 0.0005 0.0005
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1509 0.9809 1
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0271 0.1163
Trichomonas vaginalis STE family protein kinase 0.0094 0.0278 0.1606
Onchocerca volvulus 0.0203 0.1014 0.1029
Schistosoma mansoni protein kinase 0.046 0.2744 0.2797
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0053 0.0005 0.0005
Echinococcus granulosus muscleblind protein 0.0146 0.063 0.063
Brugia malayi Nuclear hormone receptor family member nhr-19 0.034 0.1934 0.197
Loa Loa (eye worm) hypothetical protein 0.0129 0.0518 0.0526
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0249 0.1321 0.1321
Echinococcus multilocularis dual specificity 0.0151 0.0661 0.0661
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1509 0.9809 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.1562 0.6703
Plasmodium falciparum protein kinase 5 0.0129 0.0519 0.658
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.034 0.1934 0.1934
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Schistosoma mansoni cpg binding protein 0.0059 0.0043 0.0044
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0095 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0225 0.1162 0.1183
Loa Loa (eye worm) hypothetical protein 0.0243 0.1284 0.1308
Echinococcus granulosus casein kinase I alpha 0.0119 0.0447 0.0447
Brugia malayi nuclear receptor NHR-67 0.0156 0.0699 0.0711
Trichomonas vaginalis aldo/keto reductase, putative 0.0131 0.0528 0.3082
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0156 0.0699 0.0708
Echinococcus granulosus aldo keto reductase 0.0131 0.0528 0.0528
Echinococcus granulosus casein kinase I alpha 0.0119 0.0447 0.0447
Onchocerca volvulus 0.0225 0.1162 0.118
Echinococcus multilocularis tyrosine protein kinase shark 0.0337 0.1917 0.1917
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0131 0.0528 0.0537
Brugia malayi Protein kinase domain containing protein 0.0305 0.1703 0.1734
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0095 0.0287 0.0287
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Echinococcus granulosus twitchin 0.015 0.0655 0.0655
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0087 0.0236 0.024
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.009 0.0252 0.151
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.1361 0.1387
Brugia malayi hypothetical protein 0.0074 0.0144 0.0144
Brugia malayi STAT protein, DNA binding domain containing protein 0.006 0.0051 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.014 0.0588 0.3685
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Brugia malayi casein kinase 1, delta 0.0119 0.0447 0.0454
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0087 0.0234 0.0234
Schistosoma mansoni serine/threonine RGC 0.0053 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0151 0.0661 0.0661
Echinococcus granulosus casein kinase i 0.0119 0.0447 0.0447
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0157 0.0707 0.0707
Brugia malayi Sex muscle abnormal protein 5 0.0103 0.0341 0.0346
Echinococcus granulosus serine threonine protein kinase nrc 0.0169 0.0786 0.0786
Leishmania major protein kinase, putative 0.0111 0.0392 0.2444
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0111 0.0392 0.0392
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.014 0.0588 0.06
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0103 0.0341 0.0346
Schistosoma mansoni protein kinase 0.0207 0.1041 0.1062
Echinococcus multilocularis aldehyde reductase 0.0093 0.0273 0.0273
Echinococcus granulosus aurora kinase A 0.0157 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0346 0.0351
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Giardia lamblia Kinase, PLK 0.0288 0.1588 1
Schistosoma mansoni nuclear receptor 0.0156 0.0699 0.0713
Echinococcus granulosus cyclin dependent kinase 1 0.0129 0.0519 0.0519
Schistosoma mansoni retinoid-x-receptor (RXR) 0.034 0.1934 0.1972
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0765 0.4474
Giardia lamblia Kinase, NEK 0.0148 0.0641 0.4018
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0053 0.0005 0.0005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Brugia malayi Nuclear hormone receptor family member nhr-41 0.034 0.1934 0.197
Echinococcus granulosus tyrosine kinase 0.0053 0.0005 0.0005
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0129 0.0519 0.3245
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Entamoeba histolytica hypothetical protein 0.0074 0.0144 0.0617
Echinococcus multilocularis protein tyrosine kinase 0.0584 0.3579 0.3579
Loa Loa (eye worm) AGC/AKT protein kinase 0.0305 0.1703 0.1734
Schistosoma mansoni thyroid hormone receptor 0.034 0.1934 0.1972
Schistosoma mansoni tensin 0.006 0.0051 0.0052
Plasmodium falciparum glycogen synthase kinase 3 0.014 0.0588 0.7472
Giardia lamblia Kinase, CMGC CDK 0.0129 0.0519 0.3245
Plasmodium falciparum calcium-dependent protein kinase 1 0.0111 0.0392 0.4956
Schistosoma mansoni cpg binding protein 0.0059 0.0043 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0588 0.3436
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0758 0.4755 0.4755
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Echinococcus multilocularis tyrosine protein kinase pr2 0.0053 0.0005 0.0005
Trichomonas vaginalis STE family protein kinase 0.0072 0.0134 0.076
Loa Loa (eye worm) cytochrome P450 family protein 0.0099 0.0314 0.0318
Giardia lamblia Kinase, CMGC CDK 0.0129 0.0519 0.3245
Schistosoma mansoni tensin 0.006 0.0051 0.0052
Echinococcus granulosus dual specificity 0.022 0.1128 0.1128
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Schistosoma mansoni protein kinase 0.0165 0.0761 0.0776
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0103 0.0341 0.0348
Schistosoma mansoni nephrin 0.0127 0.05 0.0509
Echinococcus multilocularis casein kinase i 0.0119 0.0447 0.0447
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Echinococcus granulosus natriuretic peptide receptor 1 0.0053 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0271 0.1567
Entamoeba histolytica ankyrin repeat protein 0.0053 0.0005 0.0021
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0172 0.0804 0.5043
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.014 0.0588 0.3569
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0331 0.1874 0.1874
Schistosoma mansoni nuclear hormone receptor 0.0156 0.0699 0.0713
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.1562 0.9169
Loa Loa (eye worm) SRC-1 0.0249 0.1321 0.1345
Brugia malayi Protein kinase domain containing protein 0.1509 0.9809 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0157 0.0702 0.0702
Entamoeba histolytica casein kinase, putative 0.011 0.0387 0.166
Echinococcus granulosus dual specificity 0.0151 0.0661 0.0661
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0123 0.0478 0.2786
Echinococcus granulosus NCK adaptor protein 0.0103 0.0341 0.0341
Schistosoma mansoni ste20-related kinase 0.022 0.1128 0.115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.034 0.1934 0.197
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0053 0.0005 0.0003
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0053 0.0005 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0314 0.1818
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0055 0.0019 0.0019
Echinococcus granulosus protein kinase 0.0165 0.0761 0.0761
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0053 0.0005 0.0003
Onchocerca volvulus 0.0146 0.0627 0.0634
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0148 0.0641 0.3891
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0493 0.2871
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0254 0.1361 0.1385
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0311 0.0317
Entamoeba histolytica serine/threonine protein kinase, putative 0.0058 0.0038 0.0163
Brugia malayi Protein kinase domain containing protein 0.0992 0.6331 0.6453
Echinococcus granulosus casein kinase I alpha 0.0119 0.0447 0.0447
Entamoeba histolytica serine/threonine protein kinase, putative 0.0288 0.1588 0.6816
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Schistosoma mansoni SH2A 0.006 0.0051 0.0052
Echinococcus granulosus mitogen activated protein kinase 3 0.0093 0.0271 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1205 0.1229
Schistosoma mansoni tyrosine kinase 0.0742 0.4644 0.4734
Echinococcus granulosus Vam6:Vps39 protein 0.0117 0.0436 0.0436
Brugia malayi Nuclear hormone receptor E75 0.0156 0.0699 0.0711
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0205 0.1031 0.1031
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0007 0.0005
Echinococcus multilocularis twitchin 0.0062 0.0066 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.034 0.1934 0.1934
Toxoplasma gondii aldose reductase, putative 0.0131 0.0528 0.3201
Loa Loa (eye worm) hypothetical protein 0.0194 0.0951 0.0967
Schistosoma mansoni retinoic acid receptor RXR 0.0443 0.2631 0.2682
Entamoeba histolytica protein kinase, putative 0.0082 0.0197 0.0846
Loa Loa (eye worm) nuclear hormone receptor 0.0156 0.0699 0.0711
Loa Loa (eye worm) CMGC/GSK protein kinase 0.014 0.0588 0.0598
Loa Loa (eye worm) RGC/RGC protein kinase 0.0053 0.0005 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Schistosoma mansoni nuclear receptor nhr-48 0.0156 0.0699 0.0713
Echinococcus multilocularis nuclear receptor nhr 48 0.0156 0.0699 0.0699
Brugia malayi protein kinase C II. 0.0211 0.1071 0.109
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0054 0.0007 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.004 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.1212 0.7108
Echinococcus multilocularis 0.006 0.0051 0.0051
Loa Loa (eye worm) TK/ABL protein kinase 0.0331 0.1874 0.1909
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0314 0.032
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0094 0.0278 0.1722
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Loa Loa (eye worm) AUR protein kinase 0.0157 0.0707 0.0719
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0233 0.1217 0.1238
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0166 0.0765 0.4647
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.006 0.0051 0.0051
Onchocerca volvulus Serine\/threonine kinase homolog 0.0288 0.1588 0.1615
Echinococcus granulosus SHC transforming protein 3 0.006 0.0051 0.0051
Echinococcus granulosus SH2 domain containing adapter protein F 0.006 0.0051 0.0051
Leishmania major prostaglandin f synthase, putative 0.0131 0.0528 0.3305
Echinococcus multilocularis Glutaredoxin protein 5 0.013 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0351
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0053 0.0005 0.0005
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0156 0.0699 0.0699
Brugia malayi Tyrosine-protein kinase abl-1 0.0134 0.0551 0.056
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0123 0.0478 0.2987
Echinococcus granulosus cGMP dependent protein kinase 1 0.0146 0.063 0.063
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0053 0.0005 0.0005
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0113 0.0407 0.0415
Brugia malayi Nuclear hormone receptor family member nhr-25 0.034 0.1934 0.197
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0099 0.0311 0.0311
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0767 0.4486
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0111 0.0392 0.2367
Loa Loa (eye worm) hypothetical protein 0.0183 0.0882 0.0897
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0249 0.1321 0.1321
Leishmania major casein kinase II, putative 0.011 0.0387 0.2412
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.1339 0.1365
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0523 0.3171 0.3171
Echinococcus multilocularis aldo keto reductase 0.0131 0.0528 0.0528
Entamoeba histolytica tyrosin kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis serine:threonine protein kinase 3 0.0274 0.1493 0.1493
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0084 0.0212 0.0212
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0131 0.0528 0.3082
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0053 0.0005 0.0003
Entamoeba histolytica protein kinase, putative 0.014 0.0588 0.2525
Echinococcus granulosus protein kinase 0.0053 0.0005 0.0005
Trypanosoma brucei SNF1-related protein kinases, putative 0.0099 0.0311 0.1803
Brugia malayi STE20-like kinase MST 0.0274 0.1493 0.1521
Schistosoma mansoni aldo-keto reductase 0.0131 0.0528 0.0539
Loa Loa (eye worm) hypothetical protein 0.0297 0.1648 0.1678
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Onchocerca volvulus 0.0131 0.0528 0.0534
Schistosoma mansoni serine/threonine-protein kinase 0.0179 0.0849 0.0865
Onchocerca volvulus 0.0131 0.0528 0.0534
Brugia malayi Protein kinase domain containing protein 0.059 0.3621 0.369
Schistosoma mansoni protein kinase 0.0095 0.0287 0.0293
Loa Loa (eye worm) hypothetical protein 0.015 0.0655 0.0666
Schistosoma mansoni vesicular amine transporter 0.0087 0.0236 0.024
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0151 0.0661 0.4145
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0143 0.0143
Echinococcus granulosus N chimaerin 0.0104 0.0346 0.0346
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.006 0.0051 0.0051
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0217 0.1111 0.113
Loa Loa (eye worm) TK/FER protein kinase 0.0053 0.0005 0.0003
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0177 0.0839 0.0853
Loa Loa (eye worm) RGC/RGC protein kinase 0.0053 0.0005 0.0003
Trypanosoma cruzi casein kinase, putative 0.0119 0.0447 0.2793
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Entamoeba histolytica protein kinase, putative 0.022 0.1128 0.4839
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0058 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.0223 0.1147 0.1168
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0099 0.0311 0.3921
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.063 0.0643
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0172 0.0804 0.5043
Brugia malayi Cytochrome P450 family protein 0.0099 0.0314 0.0318
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0238 0.1249 0.1249
Echinococcus granulosus tyrosine protein kinase HCK 0.0145 0.0626 0.0626
Entamoeba histolytica protein kinase, putative 0.0151 0.0661 0.2837
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0095 0.0287 0.0287
Echinococcus granulosus CDC7 cell division cycle 7 0.0099 0.0314 0.0314
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0093 0.0271 0.0274
Echinococcus multilocularis nervana 2 0.013 0.052 0.052
Loa Loa (eye worm) TK protein kinase 0.0305 0.1698 0.1729
Plasmodium falciparum protein kinase, putative 0.0093 0.0271 0.3406
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0092 0.0267 0.027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.034 0.1934 0.1934
Loa Loa (eye worm) hypothetical protein 0.0117 0.0436 0.0442
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Echinococcus granulosus expressed conserved protein 0.006 0.0051 0.0051
Toxoplasma gondii NEK kinase 0.0058 0.0038 0.0202
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0156 0.0699 0.0699
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0261 0.1405 0.1405
Entamoeba histolytica protein kinase, putative 0.0079 0.018 0.0773
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0231 0.1205 0.1205
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0038 0.0039
Loa Loa (eye worm) hypothetical protein 0.0107 0.0365 0.037
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0131 0.0528 0.3305
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0096 0.0294 0.0298
Entamoeba histolytica hypothetical protein 0.0074 0.0144 0.0617
Schistosoma mansoni nuclear receptor 0.0156 0.0699 0.0713
Schistosoma mansoni growth factor receptor-bound protein 0.0103 0.0341 0.0348
Giardia lamblia Aldose reductase 0.0131 0.0528 0.3305
Echinococcus granulosus serine:threonine protein kinase N2 0.0136 0.0562 0.0562
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0107 0.0365 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0572 0.3341
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0295 0.1265
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0151 0.0661 0.0672
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0066 0.0067
Echinococcus granulosus protein kinase C gamma type 0.0209 0.1056 0.1056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0156 0.0699 0.0699
Echinococcus multilocularis c src tyrosine kinase 0.0156 0.07 0.07
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0183 0.0882 0.0897
Brugia malayi Protein kinase domain containing protein 0.0113 0.0409 0.0415
Echinococcus granulosus tyrosine protein kinase Fyn 0.0249 0.1321 0.1321
Loa Loa (eye worm) CYP4Cod1 0.0099 0.0314 0.0318
Entamoeba histolytica protein kinase domain containing protein 0.0217 0.1111 0.4766
Schistosoma mansoni protein kinase 0.0283 0.155 0.158
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0079 0.0176 0.0178
Schistosoma mansoni tyrosine protein kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis expressed protein 0.0092 0.0267 0.0267
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Entamoeba histolytica protein kinase, putative 0.0111 0.0392 0.1682
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Echinococcus multilocularis PAK box P21 Rho binding 0.0072 0.0134 0.0134
Onchocerca volvulus 0.006 0.0051 0.0047
Brugia malayi Protein kinase domain containing protein 0.0166 0.0767 0.078
Onchocerca volvulus 0.0099 0.0314 0.0315
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0104 0.0346 0.0351
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.063 0.0643
Echinococcus multilocularis activin receptor type 0.0093 0.0271 0.0271
Loa Loa (eye worm) TK/ACK protein kinase 0.0053 0.0005 0.0003
Echinococcus multilocularis tyrosine protein kinase Abl 0.0239 0.126 0.126
Brugia malayi Cytochrome P450 family protein 0.0099 0.0314 0.0318
Schistosoma mansoni suppressor of cytokine signaling 0.006 0.0051 0.0052
Schistosoma mansoni hypothetical protein 0.0164 0.0749 0.0764
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.009 0.0255 0.0255
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Brugia malayi serine/threonine kinase 12 0.0157 0.0707 0.0719
Plasmodium vivax protein kinase, putative 0.0069 0.0112 0.1364
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.1351 0.1377
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0058 0.0038 0.0209
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0271 0.1567
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Brugia malayi Receptor family ligand binding region containing protein 0.0053 0.0005 0.0003
Leishmania major protein kinase, putative 0.0166 0.0765 0.4799
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Brugia malayi integrin-linked kinase 0.0053 0.0005 0.0003
Trypanosoma brucei casein kinase I, isoform 2 0.0119 0.0447 0.2604
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0249 0.1321 0.1321
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.034 0.1934 0.197
Echinococcus multilocularis Immunoglobulin 0.0087 0.0236 0.0236
Brugia malayi Temporarily assigned gene name protein 59 0.0135 0.0558 0.0566
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0005 0.0005
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0217 0.1111 0.1111
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0053 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase csk 0.0053 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0099 0.0311 0.0315
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Echinococcus multilocularis 0.0217 0.111 0.111
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0053 0.0005 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0143 0.0143
Plasmodium falciparum NIMA related kinase 1 0.0148 0.0641 0.8148
Brugia malayi hypothetical protein 0.0156 0.0699 0.0711
Schistosoma mansoni tensin-related 0.006 0.0051 0.0052
Echinococcus granulosus tar DNA binding protein 0.0074 0.0143 0.0143
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0251 0.1339 0.1339
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0053 0.0005 0.0005
Entamoeba histolytica serine/threonine kinase, putative 0.0053 0.0005 0.0021
Onchocerca volvulus 0.006 0.0051 0.0047
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0169 0.0786 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0341 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0519 0.0529
Brugia malayi Raf kinase 0.0053 0.0005 0.0003
Echinococcus multilocularis expressed conserved protein 0.0146 0.063 0.063
Entamoeba histolytica protein kinase, putative 0.0112 0.0401 0.172
Brugia malayi Variant SH3 domain containing protein 0.0104 0.0346 0.0351
Giardia lamblia Kinase, CAMK CAMKL 0.0099 0.0311 0.1934
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Entamoeba histolytica protein kinase, putative 0.01 0.0317 0.1361
Brugia malayi Protein kinase domain containing protein 0.035 0.2006 0.2044
Echinococcus multilocularis epidermal growth factor receptor 0.0548 0.3334 0.3334
Echinococcus multilocularis insulin receptor 0.0742 0.4644 0.4644
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0053 0.0005 0.0021
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0098 0.0306 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0066 0.0067
Echinococcus granulosus roundabout 2 0.0058 0.004 0.004
Loa Loa (eye worm) casein kinase 0.0126 0.0495 0.0503
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0157 0.0707 0.3035
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0104 0.0346 0.0353
Plasmodium falciparum tyrosine kinase-like protein, putative 0.009 0.0252 0.3163
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0053 0.0005 0.0021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.034 0.1934 0.1972
Loa Loa (eye worm) hypothetical protein 0.0203 0.1014 0.1031
Echinococcus granulosus epidermal growth factor receptor 0.0766 0.4804 0.4804
Brugia malayi hypothetical protein 0.0077 0.0168 0.017
Loa Loa (eye worm) oxidoreductase 0.0131 0.0528 0.0537
Echinococcus multilocularis suppressor of cytokine signaling 6 0.006 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Giardia lamblia Kinase, CAMK CAMKL 0.0099 0.0311 0.1934
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.034 0.1934 0.197
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Echinococcus granulosus geminin 0.0164 0.0749 0.0749
Echinococcus multilocularis mitogen activated protein kinase 14 0.0172 0.0804 0.0804
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.026 0.1396 0.1396
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Trypanosoma brucei cdc2-related kinase 3 0.0129 0.0519 0.3026
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.018 0.0184
Brugia malayi phosphoinositide-dependent protein kinase I 0.009 0.0255 0.0258
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0518 0.3137 0.3198
Brugia malayi putative serine/threonine kinase SADA gamma 0.0099 0.0311 0.0315
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0288 0.1588 0.1619
Schistosoma mansoni ephrin receptor 0.007 0.0116 0.0118
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0992 0.6331 0.6453
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0379 0.22 0.2241
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0038 0.0195
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0588 0.2525
Trypanosoma brucei NIMA-related protein kinase 0.0058 0.0038 0.0195
Loa Loa (eye worm) oxidoreductase 0.0131 0.0528 0.0537
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0099 0.0315 0.0315
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0288 0.1588 0.1617
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0093 0.0271 0.1681
Echinococcus multilocularis cyclin dependent kinase 1 0.0129 0.0519 0.0519
Brugia malayi map kinase activated protein kinase protein 2 0.0418 0.2463 0.251
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0131 0.0528 0.0537
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0123 0.0478 0.2786
Brugia malayi hypothetical protein 0.0183 0.0882 0.0897
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0166 0.0765 0.4799
Schistosoma mansoni adapter molecule crk 0.0103 0.0341 0.0348
Brugia malayi MH2 domain containing protein 0.0132 0.0534 0.0542
Echinococcus granulosus contactin 0.0058 0.004 0.004
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0131 0.0528 0.0528
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.1562 0.5
Echinococcus granulosus expressed conserved protein 0.009 0.0256 0.0256
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0117 0.0436 0.2721
Loa Loa (eye worm) TK/EGFR protein kinase 0.0766 0.4804 0.4896
Brugia malayi Variant SH3 domain containing protein 0.0071 0.0123 0.0124
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.034 0.1934 0.197
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0131 0.0528 0.0528
Brugia malayi Nuclear hormone receptor E75 0.0156 0.0699 0.0711
Echinococcus granulosus retinal guanylyl cyclase 2 0.0053 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.009 0.0255 0.1474
Echinococcus granulosus hypothetical protein 0.0131 0.0528 0.0528
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0431 0.2552 0.2552
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0349 0.1999 0.2036
Brugia malayi Protein kinase domain containing protein 0.0113 0.0409 0.0415
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0288 0.1588 0.1588
Echinococcus multilocularis myotubularin protein 13 0.0053 0.0005 0.0005
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0146 0.063 0.063
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.006 0.0051 0.0051
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0095 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0767 0.0782
Schistosoma mansoni protein kinase 0.0119 0.0447 0.0456
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Loa Loa (eye worm) cytochrome P450 family protein 0.0099 0.0314 0.0318
Schistosoma mansoni tyrosine kinase 0.0494 0.2976 0.3034
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0231 0.1205 0.1205
Trypanosoma cruzi cytochrome P450, putative 0.0099 0.0314 0.1951
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0661 0.3865
Entamoeba histolytica aldose reductase, putative 0.0131 0.0528 0.2267
Echinococcus granulosus aldo keto reductase 0.0131 0.0528 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0707 0.4135
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0157 0.0707 0.3035
Loa Loa (eye worm) hypothetical protein 0.0055 0.0016 0.0014
Echinococcus granulosus suppressor of cytokine signaling 7 0.006 0.0051 0.0051
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.034 0.1934 0.197
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0144 0.0146
Brugia malayi Protein kinase domain containing protein 0.0475 0.2847 0.2901
Leishmania major protein kinase A catalytic subunit 0.0123 0.0478 0.2987
Echinococcus granulosus rho-associated protein kinase 1 0.0346 0.1976 0.1976
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0099 0.0315 0.0315
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0176 0.018
Brugia malayi hypothetical protein 0.0238 0.1249 0.1271
Brugia malayi Protein kinase domain containing protein 0.007 0.0117 0.0117
Brugia malayi probable protein kinase 0.0283 0.155 0.1579
Echinococcus granulosus tyrosine kinase 0.0205 0.1031 0.1031
Echinococcus multilocularis aurora kinase A 0.0157 0.0707 0.0707
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0163 0.0745 0.0757
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1072 0.6865 0.6865
Loa Loa (eye worm) hypothetical protein 0.0125 0.0487 0.0494
Loa Loa (eye worm) hypothetical protein 0.0125 0.0486 0.0493
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0151 0.0661 0.3865
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.011 0.0387 0.489
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0765 0.078
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0092 0.0267 0.1653
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.006 0.0051 0.005
Leishmania major aldo-keto reductase-like protein 0.0131 0.0528 0.3305
Loa Loa (eye worm) TK/FER protein kinase 0.0113 0.0409 0.0415
Echinococcus granulosus tyrosine protein kinase shark 0.0337 0.1917 0.1917
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0087 0.0234 0.0236
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0129 0.0519 0.3143
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0143 0.0146
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0215 0.1097 0.1097
Echinococcus granulosus dual specificity protein kinase clk2 0.0166 0.0765 0.0765
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0443 0.2631 0.2631
Brugia malayi cell division control protein 2 homolog 0.0129 0.0519 0.0527
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0007 0.0005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0582 1
Onchocerca volvulus Bile acid receptor homolog 0.0501 0.3018 0.3073
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Toxoplasma gondii aurora kinase 0.0157 0.0707 0.4295
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0707 0.4135
Loa Loa (eye worm) thyroid receptor interactor 0.0123 0.0473 0.048
Brugia malayi serine/threonine-protein kinase 6 0.0157 0.0707 0.0719
Schistosoma mansoni hypothetical protein 0.0107 0.0366 0.0373
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.034 0.1934 0.197
Schistosoma mansoni tyrosine kinase 0.0548 0.3334 0.3399
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Echinococcus granulosus signal transduction protein lnk realted 0.006 0.0051 0.0051
Trypanosoma cruzi cytochrome P450, putative 0.0099 0.0314 0.1951
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Echinococcus granulosus tyrosine protein kinase Fyn 0.0249 0.1321 0.1321
Brugia malayi Steroid receptor seven-up type 2 0.034 0.1934 0.197
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0177 0.0839 0.0839
Schistosoma mansoni hypothetical protein 0.0053 0.0005 0.0005
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0418 0.2463 0.2463
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0053 0.0005 0.0003
Echinococcus multilocularis titin 0.0079 0.0176 0.0176
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0215 0.1097 0.1097
Loa Loa (eye worm) TK protein kinase 0.0284 0.1558 0.1587
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0058 0.0038 0.0423
Echinococcus multilocularis serine:threonine protein kinase N2 0.0136 0.0562 0.0562
Trichomonas vaginalis STE family protein kinase 0.0095 0.0287 0.1662
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0092 0.0267 0.1653
Entamoeba histolytica receptor protein kinase, putative 0.0053 0.0005 0.0021
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0117 0.0436 0.0444
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0111 0.0392 0.0398
Onchocerca volvulus 0.014 0.0588 0.0595
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.2463 0.2511
Loa Loa (eye worm) TK/ROR protein kinase 0.0076 0.0158 0.0159
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0093 0.0271 0.1628
Toxoplasma gondii NEK kinase 0.0058 0.0038 0.0202
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus multilocularis myosin iiia 0.0094 0.0278 0.0278
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0156 0.0699 0.0711
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0562 0.3435 0.3498
Plasmodium falciparum calcium-dependent protein kinase 4 0.0111 0.0392 0.4956
Echinococcus granulosus NDR protein kinase 0.0166 0.0767 0.0767
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0087 0.0236 0.024
Brugia malayi SH2 domain containing protein 0.006 0.0051 0.005
Loa Loa (eye worm) TK/DDR protein kinase 0.0053 0.0005 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Brugia malayi Hr1 repeat family protein 0.0302 0.1682 0.1713
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Loa Loa (eye worm) steroid hormone receptor 0.034 0.1934 0.197
Brugia malayi CXXC zinc finger family protein 0.0056 0.0022 0.002
Leishmania major casein kinase, putative 0.0119 0.0447 0.2793
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Echinococcus granulosus cpg binding protein 0.0059 0.0043 0.0043
Onchocerca volvulus 0.0194 0.0951 0.0964
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0157 0.0702 0.0702
Brugia malayi nuclear receptor RXR 0.0156 0.0699 0.0711
Brugia malayi P38 map kinase family protein 2 0.0172 0.0804 0.0817
Echinococcus granulosus serine:threonine kinase SAD 1 0.0099 0.0311 0.0311
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0051 0.005
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0099 0.0311 0.1803
Echinococcus multilocularis adam 0.0077 0.0168 0.0168
Entamoeba histolytica casein kinase, putative 0.0119 0.0447 0.1919
Echinococcus multilocularis tensin 0.006 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Entamoeba histolytica protein kinase, putative 0.0092 0.0267 0.1144
Entamoeba histolytica protein kinase, putative 0.0166 0.0767 0.329
Leishmania major protein kinase, putative 0.0058 0.0038 0.0209
Entamoeba histolytica protein kinase, putative 0.0095 0.0287 0.1233
Echinococcus multilocularis dual specificity 0.0151 0.0661 0.0661
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0641 0.3747
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0295 0.0299
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0058 0.0038 0.0209
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0154 0.0686 0.0686
Onchocerca volvulus 0.0096 0.0294 0.0295
Plasmodium vivax casein kinase 1, putative 0.0119 0.0447 0.5663
Leishmania major protein kinase, putative 0.0166 0.0765 0.4799
Echinococcus granulosus cyclin dependent kinase 5 0.0129 0.0519 0.0519
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Trypanosoma brucei cdc2-related kinase 1 0.0129 0.0519 0.3026
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0062 0.0066 0.0065
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.034 0.1934 0.1934
Echinococcus multilocularis aldo keto reductase 0.0131 0.0528 0.0528
Entamoeba histolytica protein kinase, putative 0.0054 0.0007 0.003
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0251 0.1339 0.1339
Brugia malayi ephrin receptor 1 precursor 0.0085 0.0218 0.022
Brugia malayi Common central domain of tyrosinase family protein 0.0096 0.0294 0.0298
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0053 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Schistosoma mansoni tyrosine kinase 0.0249 0.1321 0.1346
Schistosoma mansoni protein kinase 0.011 0.0387 0.0394
Echinococcus multilocularis CDC7 cell division cycle 7 0.0099 0.0314 0.0314
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Schistosoma mansoni thyroid hormone receptor 0.034 0.1934 0.1972
Brugia malayi Immunoglobulin I-set domain containing protein 0.0055 0.0017 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0505 0.3048 0.3107
Loa Loa (eye worm) DR-78 0.0156 0.0699 0.0711
Echinococcus multilocularis neuroglian 0.011 0.0389 0.0389
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0111 0.0392 0.0392
Echinococcus multilocularis expressed conserved protein 0.009 0.0256 0.0256
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Onchocerca volvulus 0.0096 0.0294 0.0295
Loa Loa (eye worm) TK/INSR protein kinase 0.0742 0.4644 0.4733
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0111 0.0392 0.0392
Onchocerca volvulus 0.0079 0.0176 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0038 0.0195
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0169 0.0786 0.4932
Trichomonas vaginalis AGC family protein kinase 0.009 0.0255 0.1474
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0261 0.1405 0.1405
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.1098 0.1119
Loa Loa (eye worm) hypothetical protein 0.034 0.1934 0.197
Loa Loa (eye worm) RGC/RGC protein kinase 0.0053 0.0005 0.0003
Echinococcus multilocularis protein kinase c epsilon type 0.0211 0.1071 0.1071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.034 0.1934 0.197
Entamoeba histolytica tyrosin kinase, putative 0.0053 0.0005 0.0021
Echinococcus multilocularis casein kinase I delta 0.0119 0.0447 0.0447
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0058 0.004 0.004
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0099 0.0311 0.1934
Mycobacterium ulcerans hypothetical protein 0.0107 0.0364 0.188
Schistosoma mansoni protein kinase 0.0095 0.0287 0.0293
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.006 0.0051 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0314 0.1818
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0111 0.0392 0.0392
Schistosoma mansoni tyrosine kinase 0.0249 0.1321 0.1346
Brugia malayi Protein kinase domain containing protein 0.0053 0.0005 0.0003
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0166 0.0767 0.0767
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Loa Loa (eye worm) hypothetical protein 0.0146 0.063 0.064
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Trichomonas vaginalis aldo/keto reductase, putative 0.0131 0.0528 0.3082
Echinococcus multilocularis tyrosine protein kinase csk 0.0053 0.0005 0.0005
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0156 0.0699 0.0713
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0053 0.0005 0.0003
Entamoeba histolytica hypothetical protein 0.0053 0.0005 0.0021
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0165 0.0761 0.0774
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0172 0.0804 0.0817
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0172 0.0804 0.4702
Schistosoma mansoni tyrosine kinase 0.0095 0.0287 0.0293
Onchocerca volvulus 0.0113 0.0409 0.0413
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0117 0.0436 0.0436
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Brugia malayi steroid hormone receptor 0.034 0.1934 0.197
Echinococcus granulosus cyclin dependent kinase 0.0129 0.0519 0.0519
Echinococcus granulosus aldehyde reductase 0.0093 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0053 0.0005 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.1111 0.1132
Echinococcus multilocularis muscleblind protein 0.0146 0.063 0.063
Echinococcus granulosus nervana 2 0.013 0.052 0.052
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.011 0.0387 0.0392
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0248 0.1319 0.1342
Plasmodium vivax glycogen synthase kinase 3, putative 0.014 0.0588 0.7472
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Giardia lamblia Kinase, CMGC CLK 0.0166 0.0765 0.4799
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.1339 0.1365
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0053 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0156 0.07 0.0713
Giardia lamblia Kinase, AGC AKT 0.0128 0.0507 0.3168
Brugia malayi serine/threonine-protein kinase PAK 7 0.0248 0.1319 0.1342
Echinococcus multilocularis suppressor of cytokine signaling 7 0.006 0.0051 0.0051
Schistosoma mansoni ephrin receptor 0.012 0.0457 0.0466
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0079 0.018 0.018
Echinococcus granulosus growth factor receptor bound protein 2 0.0105 0.0355 0.0355
Giardia lamblia Kinase, NEK 0.0148 0.0641 0.4018
Trypanosoma cruzi casein kinase, putative 0.0119 0.0447 0.2793
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0058 0.0038 0.0423
Brugia malayi Tensin 0.006 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.005
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0058 0.0038 0.0195
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0093 0.0271 0.1681
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0131 0.0528 0.3082
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0093 0.0271 0.1627
Trichomonas vaginalis STE family protein kinase 0.0058 0.0038 0.0195
Brugia malayi Protein kinase domain containing protein 0.0232 0.1212 0.1234
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0707 0.4135
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0053 0.0005 0.0005
Loa Loa (eye worm) ShTK domain-containing protein 0.0096 0.0294 0.0298
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.02 0.0992 0.0992
Echinococcus multilocularis serine:threonine protein kinase 0.0125 0.0486 0.0486
Entamoeba histolytica SH2-protein kinase domain containing protein 0.01 0.0317 0.1361
Onchocerca volvulus Papilin homolog 0.0085 0.0221 0.0221
Echinococcus multilocularis NCK adaptor protein 0.0105 0.0355 0.0355
Brugia malayi Egg laying defective protein 4 0.0146 0.063 0.0641
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Trypanosoma brucei protein kinase, putative 0.0093 0.0271 0.1566
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.1071 0.1092
Trichomonas vaginalis aldo-keto reductase, putative 0.0131 0.0528 0.3082
Schistosoma mansoni serine/threonine protein kinase 0.1509 0.9809 1
Echinococcus multilocularis tensin 0.006 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0146 0.0627 0.0637
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0093 0.0271 0.1567
Brugia malayi tRNA modification GTPase TrmE family protein 0.006 0.0051 0.005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0093 0.0271 0.1681
Schistosoma mansoni atypical protein kinase C 0.0303 0.169 0.1723
Loa Loa (eye worm) hypothetical protein 0.0077 0.0168 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.1588 0.9324
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0099 0.0315 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-49 0.034 0.1934 0.197
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0392 0.04
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0137 0.057 0.3566
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0387 0.2249
Brugia malayi Protein kinase domain containing protein 0.0208 0.1048 0.1066
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0093 0.0271 0.168
Giardia lamblia Kinase, CMGC CK2 0.011 0.0387 0.2412
Schistosoma mansoni neuroglian 0.0058 0.004 0.0041
Trypanosoma cruzi aurora B kinase, putative 0.0157 0.0707 0.4435
Echinococcus multilocularis tyrosine protein kinase Blk 0.0205 0.1031 0.1031
Loa Loa (eye worm) hypothetical protein 0.0218 0.1117 0.1136
Echinococcus multilocularis SH2 motif 0.006 0.0051 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Onchocerca volvulus 0.0085 0.0217 0.0216
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0573 0.0573
Echinococcus granulosus mitogen activated protein kinase 11 0.0172 0.0804 0.0804
Plasmodium falciparum serine/threonine protein kinase 0.0092 0.0267 0.3352
Loa Loa (eye worm) tyrosinase 1 0.0096 0.0294 0.0298
Entamoeba histolytica serine/threonine kinase, putative 0.0053 0.0005 0.0021
Plasmodium falciparum calcium-dependent protein kinase 3 0.0111 0.0392 0.4956
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.006 0.0051 0.0047
Schistosoma mansoni tyrosine kinase 0.0494 0.2976 0.3034
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0123 0.0478 0.2987
Plasmodium falciparum casein kinase 1 0.0119 0.0447 0.5663
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0249 0.1321 0.1321
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0005 0.0021
Schistosoma mansoni tyrosine kinase 0.0053 0.0005 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0053 0.0005 0.0021
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.034 0.1934 0.1972
Brugia malayi hypothetical protein 0.0053 0.0005 0.0003
Toxoplasma gondii casein kinase I 0.0119 0.0447 0.2704
Brugia malayi p70 ribosomal S6 kinase beta 0.0296 0.164 0.167
Echinococcus multilocularis muscleblind protein 1 0.0146 0.063 0.063
Trypanosoma cruzi casein kinase, putative 0.0119 0.0447 0.2793
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0123 0.0478 0.0478
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0117 0.0436 0.2537
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0189 0.0921 0.0937
Brugia malayi Kinase associated domain 1 family protein 0.0107 0.0366 0.0371
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0634 0.3917 0.3991
Echinococcus granulosus activated cdc42 kinase 1 0.0053 0.0005 0.0005
Giardia lamblia Kinase, CDC7 0.0099 0.0314 0.195
Entamoeba histolytica ankyrin repeat protein 0.0053 0.0005 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0519 0.3026
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0111 0.0392 0.2279
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0093 0.0271 0.1681
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.034 0.1934 0.1972
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0123 0.0478 0.2987
Echinococcus multilocularis protein kinase c iota type 0.0297 0.1647 0.1647
Loa Loa (eye worm) hypothetical protein 0.0123 0.0478 0.0485
Entamoeba histolytica PH domain containing protein kinase, putative 0.0133 0.0541 0.2322
Brugia malayi Nuclear hormone receptor-like 1 0.0183 0.0882 0.0897
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0053 0.0005 0.0005
Schistosoma mansoni protein kinase 0.046 0.2744 0.2797
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Brugia malayi C1-like domain containing protein 0.0233 0.1217 0.1238
Echinococcus granulosus cGMP dependent protein kinase 0.0146 0.063 0.063
Entamoeba histolytica protein kinase, putative 0.0053 0.0005 0.0021
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0062 0.0066 0.0384
Schistosoma mansoni serine/threonine kinase 0.0232 0.1212 0.1236
Loa Loa (eye worm) hypothetical protein 0.0127 0.0499 0.0507
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0389 0.227 0.2312
Echinococcus granulosus glycogen synthase kinase 3 beta 0.014 0.0588 0.0588
Loa Loa (eye worm) protein-tyrosine phosphatase 0.006 0.0051 0.005
Onchocerca volvulus 0.0131 0.0528 0.0534
Trypanosoma cruzi casein kinase, putative 0.0119 0.0447 0.2793
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0389 0.227 0.227
Giardia lamblia Kinase, NEK 0.0148 0.0641 0.4018
Entamoeba histolytica serine/threonine kinase, putative 0.0053 0.0005 0.0021
Entamoeba histolytica casein kinase 1, putative 0.0119 0.0447 0.1919
Loa Loa (eye worm) oxidoreductase 0.0131 0.0528 0.0537
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0238 0.1249 0.1249
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0038 0.0195
Schistosoma mansoni tyrosine kinase 0.0337 0.1917 0.1954
Echinococcus multilocularis transfer RNA-Thr 0.0053 0.0005 0.0005
Leishmania major cytochrome p450-like protein 0.0099 0.0314 0.1951
Echinococcus multilocularis mitogen activated protein kinase 14 0.0172 0.0804 0.0804
Brugia malayi ShTK domain containing protein 0.0096 0.0294 0.0298
Brugia malayi Protein kinase domain containing protein 0.009 0.0255 0.0258
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0095 0.0287 0.0287
Schistosoma mansoni tyrosine-protein kinase zap-70 0.006 0.0051 0.0052
Schistosoma mansoni protein kinase 0.0053 0.0005 0.0005
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0096 0.0294 0.0298
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0053 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0314 0.1818
Toxoplasma gondii AGC kinase 0.0123 0.0478 0.2893
Giardia lamblia Kinase, CMGC GSK 0.014 0.0588 0.3685
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0296 0.164 0.167
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0093 0.0271 0.1681
Loa Loa (eye worm) hypothetical protein 0.0156 0.0699 0.0711
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1509 0.9809 0.9809
Brugia malayi nuclear hormone receptor family member nhr-6 0.0156 0.0699 0.0711
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0311 0.1803
Loa Loa (eye worm) RGC/RGC protein kinase 0.0053 0.0005 0.0003
Loa Loa (eye worm) TK/EPH protein kinase 0.0139 0.0581 0.059
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0127 0.0501 0.292
Trichomonas vaginalis STE family protein kinase 0.0095 0.0287 0.1662
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.0534 0.0542
Entamoeba histolytica serine/threonine kinase, putative 0.0053 0.0005 0.0021
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.009 0.0255 0.0258
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0177 0.0836 0.0851
Onchocerca volvulus 0.0079 0.0181 0.018
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0166 0.0765 0.4799
Brugia malayi Pleckstrin Homology Domain 0.0053 0.0005 0.0003
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0758 0.4755 0.4755
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.004 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.034 0.1934 0.197
Trichomonas vaginalis AGC family protein kinase 0.0305 0.1703 1
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.1351 0.1377
Plasmodium falciparum NIMA related kinase 2 0.0058 0.0038 0.0423
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0146 0.063 0.063
Echinococcus granulosus protein tyrosine kinase 0.0584 0.3579 0.3579

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 4.6535 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.9341 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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