Detailed information for compound 1353258

Basic information

Technical information
  • TDR Targets ID: 1353258
  • Name: (Z)-3-[2-(4-fluorophenoxy)phenyl]prop-2-enoic acid
  • MW: 258.244 | Formula: C15H11FO3
  • H donors: 1 H acceptors: 2 LogP: 3.5 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)/C=C\c1ccccc1Oc1ccc(cc1)F
  • InChi: 1S/C15H11FO3/c16-12-6-8-13(9-7-12)19-14-4-2-1-3-11(14)5-10-15(17)18/h1-10H,(H,17,18)/b10-5-
  • InChiKey: BXEPYPAITBZKTN-YHYXMXQVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (Z)-3-[2-(4-fluorophenoxy)phenyl]acrylic acid
  • (Z)-3-[2-(4-fluorophenoxy)phenyl]-2-propenoic acid
  • MLS000755217
  • SMR000338092
  • 1P-050

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus epidermal growth factor receptor 0.0798 0.0791 0.2425
Entamoeba histolytica casein kinase, putative 0.019 0.0066 0.0245
Loa Loa (eye worm) AGC/PKA protein kinase 0.0863 0.0868 0.0857
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0423 0.0344 0.0657
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0529 0.047 0.4592
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Loa Loa (eye worm) protein kinase domain-containing protein 0.0302 0.02 0.0188
Echinococcus granulosus NDR protein kinase 0.0353 0.0259 0.0758
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0331 0.0234 0.0435
Leishmania major protein kinase A catalytic subunit isoform 2 0.0863 0.0868 0.8537
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0181 0.0055 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0987 0.1016 0.3154
Entamoeba histolytica protein kinase, putative 0.024 0.0125 0.0466
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Brugia malayi serine/threonine kinase 12 0.0351 0.0257 0.0245
Echinococcus multilocularis serine:threonine protein kinase N2 0.0353 0.0259 0.0487
Brugia malayi P38 map kinase family protein 2 0.0508 0.0445 0.0433
Loa Loa (eye worm) CAMK protein kinase 0.0196 0.0073 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0416 0.0336 0.3255
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0407 0.0325 0.3146
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis CMGC family protein kinase 0.0964 0.0989 0.9733
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0055 0.0473
Echinococcus granulosus serine:threonine protein kinase TAO1 0.07 0.0674 0.2058
Trypanosoma cruzi casein kinase, putative 0.0356 0.0263 0.2535
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.2387 0.2685 0.5373
Brugia malayi Protein kinase domain containing protein 0.0766 0.0752 0.0741
Toxoplasma gondii AGC kinase 0.0863 0.0868 0.8537
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0331 0.0234 0.2243
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0172 0.0044 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0055 0.0149
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0338 0.0242 0.2326
Trichomonas vaginalis STE family protein kinase 0.0241 0.0127 0.1183
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Brugia malayi C1-like domain containing protein 0.0608 0.0564 0.0552
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0046 0.0387
Plasmodium vivax protein kinase Crk2 0.0917 0.0932 0.9169
Trichomonas vaginalis CK1 family protein kinase 0.0356 0.0263 0.2535
Entamoeba histolytica protein kinase, putative 0.0353 0.0259 0.0966
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1019 0.1054 0.1043
Entamoeba histolytica PH domain containing protein kinase, putative 0.0884 0.0893 0.3324
Echinococcus granulosus cGMP dependent protein kinase 0.0224 0.0107 0.0278
Echinococcus granulosus raf serine:threonine protein kinase 0.0206 0.0084 0.0209
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Echinococcus multilocularis epidermal growth factor receptor 0.0798 0.0791 0.1557
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Onchocerca volvulus Serine\/threonine kinase homolog 0.0359 0.0267 0.0674
Loa Loa (eye worm) AGC/PKN protein kinase 0.1019 0.1054 0.1043
Trypanosoma cruzi casein kinase, putative 0.0356 0.0263 0.2535
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2414 0.2717 0.2708
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Echinococcus granulosus tyrosine protein kinase Fyn 0.0422 0.0343 0.1019
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0428 0.035 0.0338
Schistosoma mansoni protein kinase 0.139 0.1496 0.4657
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0592 0.0545 0.1653
Echinococcus granulosus mitogen activated protein kinase 15 0.0181 0.0055 0.0117
Loa Loa (eye worm) TK/EGFR protein kinase 0.0798 0.0791 0.078
Trichomonas vaginalis CMGC family protein kinase 0.0987 0.1016 1
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0046 0.0387
Echinococcus granulosus tyrosine protein kinase shark 0.1103 0.1154 0.3565
Entamoeba histolytica hypothetical protein 0.0144 0.0011 0.0039
Echinococcus granulosus serine:threonine protein kinase N2 0.1019 0.1054 0.325
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0863 0.0868 0.8537
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0964 0.0989 0.9733
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Brugia malayi casein kinase I 0.0356 0.0263 0.0251
Brugia malayi Protein kinase domain 0.0241 0.0127 0.0115
Giardia lamblia Kinase, CMGC CLK 0.0987 0.1016 1
Echinococcus granulosus mitogen activated protein kinase 0.0174 0.0046 0.009
Brugia malayi Protein kinase domain containing protein 0.033 0.0233 0.0221
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0546 0.049 0.095
Echinococcus multilocularis dual specificity 0.0766 0.0752 0.1479
Echinococcus multilocularis NCK adaptor protein 0.0163 0.0034 0.0032
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0987 0.1016 1
Echinococcus multilocularis protein kinase c iota type 0.0523 0.0463 0.0897
Trichomonas vaginalis CAMK family protein kinase 0.0331 0.0234 0.2243
Schistosoma mansoni protein kinase 0.0241 0.0127 0.0373
Trichomonas vaginalis STE family protein kinase 0.0338 0.0242 0.2326
Entamoeba histolytica protein kinase, putative 0.0144 0.0011 0.0039
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0144 0.0011 0.0031
Brugia malayi Fibronectin type III domain containing protein 0.0268 0.0159 0.0147
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0267 0.2574
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0917 0.0932 0.9169
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Echinococcus multilocularis dual specificity mitogen activated protein 0.0428 0.035 0.0669
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0055 0.0473
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0338 0.0242 0.0901
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0196 0.0073 0.0061
Echinococcus granulosus dual specificity protein kinase clk2 0.0987 0.1016 0.3132
Schistosoma mansoni serine/threonine protein kinase 0.1044 0.1084 0.3368
Brugia malayi Furin-like cysteine rich region family protein 0.0798 0.0791 0.078
Brugia malayi ephrin receptor 1 precursor 0.0147 0.0014 0.0002
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0529 0.047 0.1448
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0224 0.0107 0.0179
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0112 0.1035
Toxoplasma gondii histone kinase SNF1, putative 0.0226 0.0108 0.1002
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.2669
Loa Loa (eye worm) casein kinase 0.0179 0.0052 0.004
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0282 0.0175 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Brugia malayi cyclin-dependent kinase 9 0.0452 0.0378 0.0367
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0145 0.0012 0.0046
Schistosoma mansoni protein kinase 0.022 0.0101 0.0293
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0112 0.1035
Trichomonas vaginalis AGC family protein kinase 0.0351 0.0257 0.2477
Brugia malayi Protein kinase domain containing protein 0.0987 0.1016 0.1005
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0987 0.1016 0.1005
Giardia lamblia Kinase, PLK 0.0359 0.0267 0.2574
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0174 0.0046 0.0387
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0046 0.012
Echinococcus granulosus activated cdc42 kinase 1 0.0458 0.0385 0.1153
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.0272 0.0828
Trichomonas vaginalis CMGC family protein kinase 0.0917 0.0932 0.9169
Trichomonas vaginalis STE family protein kinase 0.0428 0.035 0.3395
Plasmodium falciparum calcium-dependent protein kinase 7 0.0144 0.0011 0.0031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0361 0.027 0.0258
Trichomonas vaginalis protein kinase atmrk1, putative 0.0181 0.0055 0.0473
Echinococcus granulosus cyclin dependent kinase 9 0.051 0.0447 0.1346
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0189 0.0065 0.0179
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0164 0.0035 0.0023
Onchocerca volvulus 0.0218 0.0099 0.0139
Leishmania major serine/threonine-protein kinase a, putative 0.0144 0.0011 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Brugia malayi Variant SH3 domain containing protein 0.0189 0.0065 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.2669
Schistosoma mansoni tyrosine kinase 0.0592 0.0545 0.1681
Echinococcus multilocularis cyclin dependent kinase 9 0.0452 0.0378 0.0726
Echinococcus granulosus c-Jun N-terminal kinases 0.0828 0.0826 0.2537
Onchocerca volvulus Serine\/threonine kinase homolog 0.0254 0.0141 0.0275
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0161 0.0031 0.0027
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0144 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.029 0.0185 0.0173
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus granulosus casein kinase I alpha 0.0356 0.0263 0.0769
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0174 0.0046 0.0387
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.07 0.0674 0.0662
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0046 0.0122
Echinococcus multilocularis serine threonine protein kinase 0.0393 0.0308 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Brugia malayi Temporarily assigned gene name protein 59 0.0529 0.047 0.0459
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1574 0.1716 0.1706
Echinococcus multilocularis N chimaerin 0.0189 0.0065 0.0094
Plasmodium falciparum cGMP-dependent protein kinase 0.0224 0.0107 0.0983
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.2669
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0226 0.0108 0.1002
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0785 0.0775 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Entamoeba histolytica protein kinase, putative 0.0241 0.0127 0.0472
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0181 0.0055 0.0473
Entamoeba histolytica protein kinase domain containing protein 0.0964 0.0989 0.3683
Echinococcus granulosus dual specificity 0.0766 0.0752 0.2303
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0189 0.0065 0.0179
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0253 0.0141 0.0248
Echinococcus multilocularis protein tyrosine kinase 0.0637 0.0599 0.117
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0798 0.079 0.1556
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0174 0.0046 0.0387
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0964 0.0989 0.9733
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0828 0.0826 0.0815
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0181 0.0055 0.0473
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0174 0.0046 0.0387
Echinococcus granulosus serine:threonine protein kinase 3 0.1052 0.1093 0.3374
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0347 0.0252 0.0736
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0519 0.0458 0.0447
Schistosoma mansoni serine/threonine protein kinase 0.0917 0.0932 0.2892
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1267 0.1349 0.4177
Schistosoma mansoni serine/threonine protein kinase 0.0828 0.0826 0.2561
Trichomonas vaginalis STE family protein kinase 0.0428 0.035 0.3395
Echinococcus granulosus tyrosine protein kinase ABL1 0.0423 0.0344 0.1023
Leishmania major protein kinase, putative 0.0987 0.1016 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0964 0.0989 0.0978
Entamoeba histolytica protein kinase, putative 0.0475 0.0406 0.1511
Brugia malayi Stress-activated protein kinase jnk-1 0.0828 0.0826 0.0815
Leishmania major casein kinase II, putative 0.019 0.0066 0.0579
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Plasmodium falciparum casein kinase 1 0.0356 0.0263 0.2535
Schistosoma mansoni serine/threonine kinase 0.0843 0.0844 0.2617
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0108 0.0316
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0359 0.0267 0.0782
Brugia malayi Protein kinase domain containing protein 0.0686 0.0657 0.0646
Toxoplasma gondii casein kinase I 0.0356 0.0263 0.2535
Leishmania major serine/threonine kinase-like protein, putative 0.0181 0.0055 0.0473
Brugia malayi casein kinase 1, delta 0.0356 0.0263 0.0251
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0517 0.0456 0.0882
Echinococcus multilocularis casein kinase ii subunit alpha 0.019 0.0066 0.0097
Entamoeba histolytica protein kinase, putative 0.0964 0.0989 0.3683
Echinococcus multilocularis protein kinase c epsilon type 0.0442 0.0367 0.0703
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0482 0.0413 0.1241
Brugia malayi Fes/CIP4 homology domain containing protein 0.043 0.0352 0.0341
Echinococcus multilocularis Immunoglobulin 0.0255 0.0143 0.0252
Echinococcus multilocularis expressed protein 0.0173 0.0046 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.0162 0.0483
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Loa Loa (eye worm) gastrulation defective protein 1 0.0544 0.0487 0.0476
Echinococcus granulosus cyclin dependent kinase 9 0.0452 0.0378 0.1131
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0442 0.0367 0.0355
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0254 0.0141 0.013
Giardia lamblia Kinase, CAMK CAMKL 0.0283 0.0177 0.1683
Loa Loa (eye worm) AUR protein kinase 0.0351 0.0257 0.0245
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0475 0.0406 0.0394
Plasmodium vivax tyrosine kinase-like protein, putative 0.0171 0.0043 0.0355
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0144 0.0011 0.0031
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0229 0.0112 0.1035
Echinococcus granulosus titin 0.0196 0.0073 0.0172
Echinococcus multilocularis tyrosine protein kinase Abl 0.0354 0.0261 0.0489
Loa Loa (eye worm) hypothetical protein 0.0248 0.0135 0.0123
Echinococcus multilocularis calcium dependent protein kinase 0.0207 0.0086 0.0138
Schistosoma mansoni tyrosine kinase 0.0798 0.0791 0.245
Schistosoma mansoni protein kinase 0.0428 0.035 0.1071
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Echinococcus multilocularis dual specificity protein kinase clk2 0.0987 0.1016 0.2011
Onchocerca volvulus 0.0232 0.0116 0.0194
Trichomonas vaginalis CMGC family protein kinase 0.0944 0.0964 0.9488
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Trypanosoma brucei protein kinase, putative 0.0241 0.0126 0.1176
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0189 0.0065 0.0094
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0181 0.0055 0.0473
Brugia malayi Protein kinase domain containing protein 0.0164 0.0034 0.0022
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0181 0.0055 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0863 0.0868 0.2693
Echinococcus granulosus ephrin type A receptor 4 A 0.0181 0.0054 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0046 0.0387
Echinococcus granulosus activated cdc42 kinase 1 0.0458 0.0385 0.1153
Schistosoma mansoni serine/threonine protein kinase 0.0987 0.1016 0.3154
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0241 0.0126 0.1176
Echinococcus granulosus serine:threonine protein kinase 0.0164 0.0034 0.0052
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2414 0.2717 0.2708
Loa Loa (eye worm) hypothetical protein 0.0395 0.0311 0.0299
Trypanosoma cruzi polo-like protein kinase, putative 0.0359 0.0267 0.2574
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0422 0.0343 0.0654
Entamoeba histolytica protein kinase, putative 0.024 0.0125 0.0466
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0686 0.0657 0.0646
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1359 0.146 0.1449
Loa Loa (eye worm) AGC/NDR protein kinase 0.0353 0.0259 0.0248
Brugia malayi Protein kinase domain containing protein 0.0643 0.0606 0.0595
Trichomonas vaginalis AGC family protein kinase 0.0373 0.0284 0.2739
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0234 0.0119 0.0316
Echinococcus granulosus hypothetical protein 0.0864 0.0869 0.267
Echinococcus granulosus casein kinase I delta 0.0356 0.0263 0.0769
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.079 0.0781 0.2393
Onchocerca volvulus 0.0944 0.0964 0.2887
Brugia malayi Doublecortin family protein 0.024 0.0126 0.0114
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2414 0.2717 0.8451
Loa Loa (eye worm) IKK protein kinase 0.2024 0.2252 0.2243
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0422 0.0343 0.0654
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.019 0.0066 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0226 0.0108 0.1001
Loa Loa (eye worm) hypothetical protein 0.0529 0.047 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0917 0.0932 0.2892
Schistosoma mansoni serine/threonine protein kinase 0.0684 0.0655 0.2025
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Loa Loa (eye worm) hypothetical protein 0.0529 0.047 0.0459
Schistosoma mansoni growth factor receptor-bound protein 0.0163 0.0034 0.0082
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0331 0.0234 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0108 0.0316
Brugia malayi STE20-like kinase MST 0.1052 0.1093 0.1083
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0246 0.0133 0.036
Echinococcus multilocularis myosin iiia 0.0338 0.0242 0.0451
Echinococcus granulosus casein kinase ii subunit alpha 0.019 0.0066 0.015
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0144 0.0011 0.0031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0387 0.0301 0.0289
Brugia malayi Cam kinase protein 1 0.0331 0.0234 0.0222
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0365 0.0274 0.0517
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.07 0.0674 0.1321
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1574 0.1716 0.342
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0229 0.0112 0.1035
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0249 0.0136 0.0124
Leishmania major protein kinase, putative 0.0987 0.1016 1
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0107 0.031
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0046 0.0387
Plasmodium falciparum glycogen synthase kinase 3 0.0964 0.0989 0.9733
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0331 0.0234 0.0677
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0226 0.0108 0.1002
Loa Loa (eye worm) thyroid receptor interactor 0.043 0.0352 0.0341
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0403 0.032 0.0949
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0232 0.0116 0.0104
Loa Loa (eye worm) hypothetical protein 0.0255 0.0143 0.0131
Brugia malayi Protein kinase domain containing protein 0.1574 0.1716 0.1706
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0387 0.0301 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0428 0.035 0.3395
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0766 0.0752 0.0741
Onchocerca volvulus 0.0218 0.0099 0.0139
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0226 0.0108 0.1001
Onchocerca volvulus 0.0196 0.0073 0.0057
Loa Loa (eye worm) hypothetical protein 0.0864 0.0869 0.0858
Echinococcus granulosus serine:threonine protein kinase NLK 0.0181 0.0055 0.0117
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0146 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.024 0.0125 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0267 0.0812
Echinococcus granulosus activin receptor type 0.0994 0.1024 0.3156
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.015 0.0018 0.0006
Echinococcus multilocularis Immunoglobulin 0.0255 0.0143 0.0252
Schistosoma mansoni nck2/grb4 0.0158 0.0027 0.0062
Brugia malayi Protein kinase domain containing protein 0.0172 0.0044 0.0032
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0331 0.0234 0.2243
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0422 0.0343 0.0654
Echinococcus multilocularis serine:threonine protein kinase 38 0.0353 0.0259 0.0487
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1574 0.1716 0.5327
Entamoeba histolytica protein kinase, putative 0.0331 0.0234 0.087
Schistosoma mansoni serine/threonine protein kinase 0.0353 0.0259 0.0788
Giardia lamblia Kinase, STE STE20 0.0428 0.035 0.3395
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Echinococcus multilocularis epidermal growth factor receptor 0.0592 0.0545 0.1061
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0987 0.1016 1
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0338 0.0242 0.0901
Loa Loa (eye worm) hypothetical protein 0.0291 0.0186 0.0174
Loa Loa (eye worm) hypothetical protein 0.0229 0.0113 0.0101
Brugia malayi Protein kinase domain containing protein 0.0218 0.0099 0.0087
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0517 0.0456 0.1374
Echinococcus multilocularis 0.0864 0.0869 0.1714
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0338 0.0242 0.2326
Plasmodium falciparum MO15-related protein kinase 0.0181 0.0055 0.0473
Echinococcus multilocularis neuroglian 0.0314 0.0213 0.0394
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0428 0.035 0.3395
Brugia malayi Protein kinase domain containing protein 0.2414 0.2717 0.2708
Loa Loa (eye worm) hypothetical protein 0.0775 0.0763 0.0752
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0144 0.0011 0.0031
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0508 0.0445 0.4335
Entamoeba histolytica hypothetical protein 0.0766 0.0752 0.2801
Echinococcus granulosus epidermal growth factor receptor 0.0592 0.0545 0.1653
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0161 0.0031 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.0272 0.0828
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Echinococcus granulosus CDC7 cell division cycle 7 0.0944 0.0964 0.297
Echinococcus multilocularis cyclin dependent kinase 1 0.0917 0.0932 0.1842
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Onchocerca volvulus 0.0356 0.0263 0.0661
Trypanosoma cruzi casein kinase, putative 0.0356 0.0263 0.2535
Giardia lamblia Kinase, AGC PKA 0.0246 0.0133 0.1242
Brugia malayi Immunoglobulin I-set domain containing protein 0.1359 0.146 0.1449
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0226 0.0108 0.1002
Echinococcus granulosus tyrosine kinase 0.0218 0.0099 0.0253
Echinococcus granulosus tyrosine protein kinase Blk 0.0365 0.0274 0.0805
Entamoeba histolytica protein kinase domain containing protein 0.0766 0.0752 0.2801
Echinococcus granulosus cyclin dependent kinase 7 0.0684 0.0655 0.1999
Schistosoma mansoni titin 0.0196 0.0073 0.0204
Echinococcus multilocularis casein kinase I alpha 0.0356 0.0263 0.0494
Echinococcus granulosus protein kinase C gamma type 0.0393 0.0308 0.091
Leishmania major protein kinase A catalytic subunit 0.0863 0.0868 0.8537
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0073 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0044 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Entamoeba histolytica protein kinase, putative 0.0766 0.0752 0.2801
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0482 0.0413 0.0797
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0863 0.0868 0.8537
Echinococcus granulosus Protein kinase C brain isozyme 0.0482 0.0413 0.1241
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0181 0.0055 0.0043
Loa Loa (eye worm) TK protein kinase 0.0576 0.0526 0.0515
Trypanosoma cruzi casein kinase, putative 0.0356 0.0263 0.2535
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0218 0.0099 0.0367
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0267 0.2574
Loa Loa (eye worm) TK/FER protein kinase 0.0347 0.0252 0.0241
Schistosoma mansoni serine/threonine-protein kinase 0.0266 0.0157 0.0467
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0144 0.0011 0.0031
Schistosoma mansoni cell adhesion molecule 0.0304 0.0202 0.0609
Giardia lamblia Kinase, CMGC CDK 0.0917 0.0932 0.9169
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0161 0.0031 0.0042
Trypanosoma cruzi casein kinase II, putative 0.019 0.0066 0.0579
Echinococcus granulosus insulin receptor 0.0784 0.0774 0.2374
Toxoplasma gondii CMGC kinase, CK2 family 0.019 0.0066 0.0579
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0112 0.1035
Schistosoma mansoni protein kinase 0.1574 0.1716 0.5342
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Entamoeba histolytica protein kinase, putative 0.0224 0.0106 0.0396
Trypanosoma cruzi Protein kinase B 0.0266 0.0157 0.1481
Schistosoma mansoni tyrosine kinase 0.0323 0.0224 0.0677
Loa Loa (eye worm) AUR protein kinase 0.0351 0.0257 0.0245
Loa Loa (eye worm) hypothetical protein 0.0511 0.0449 0.0437
Schistosoma mansoni tyrosine kinase 0.0784 0.0774 0.2399
Onchocerca volvulus 0.0218 0.0099 0.0139
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0158 0.0027 0.0015
Echinococcus granulosus titin 0.0196 0.0073 0.0172
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.8522 1 1
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0249 0.0136 0.128
Echinococcus granulosus cyclin dependent kinase 0.0917 0.0932 0.2868
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0684 0.0655 0.0644
Brugia malayi Serine/threonine-protein kinase SULU 0.07 0.0674 0.0662
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.0367 0.1123
Echinococcus multilocularis twitchin 0.0183 0.0057 0.0078
Loa Loa (eye worm) TK/INSR protein kinase 0.0784 0.0774 0.0763
Brugia malayi intracellular kinase 0.0964 0.0989 0.0978
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0863 0.0868 0.8537
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0964 0.0989 0.0978
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0108 0.0316
Loa Loa (eye worm) TK protein kinase 0.0365 0.0274 0.0263
Loa Loa (eye worm) TK/ALK protein kinase 0.1408 0.1517 0.1507
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2414 0.2717 0.5438
Trichomonas vaginalis CAMK family protein kinase 0.0785 0.0775 0.7615
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0428 0.035 0.0338
Brugia malayi cell division control protein 2 homolog 0.0917 0.0932 0.0921
Trypanosoma brucei cdc2-related kinase 1 0.0917 0.0932 0.9169
Echinococcus multilocularis rac serine:threonine kinase 0.0266 0.0157 0.028
Schistosoma mansoni ephrin receptor 0.0181 0.0054 0.0147
Echinococcus multilocularis cyclin dependent kinase 19 0.0667 0.0635 0.1243
Schistosoma mansoni protein kinase 0.0265 0.0155 0.046
Echinococcus multilocularis mitogen activated protein kinase 11 0.0508 0.0445 0.086
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0987 0.1016 1
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.049 0.4781
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0653 0.0618 0.1882
Echinococcus multilocularis casein kinase I delta 0.0356 0.0263 0.0494
Entamoeba histolytica protein kinase, putative 0.0495 0.043 0.1601
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0241 0.0127 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0057 0.0155
Echinococcus granulosus protein tyrosine kinase 0.0637 0.0599 0.1822
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0452 0.0378 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0112 0.0326
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Leishmania major protein kinase, putative 0.0351 0.0257 0.2477
Trichomonas vaginalis CAMK family protein kinase 0.0216 0.0097 0.0887
Echinococcus granulosus protein kinase shaggy 0.0964 0.0989 0.3047
Loa Loa (eye worm) hypothetical protein 0.1267 0.1349 0.1339
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0271 0.0162 0.0291
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0987 0.1016 1
Entamoeba histolytica protein kinase, putative 0.0173 0.0046 0.017
Schistosoma mansoni tyrosine kinase 0.1002 0.1034 0.3212
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0255 0.0143 0.0424
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Schistosoma mansoni serine/threonine protein kinase 0.0667 0.0635 0.1962
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0141 0.0419
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Trypanosoma brucei protein kinase, putative 0.0231 0.0115 0.1068
Brugia malayi Egg laying defective protein 4 0.0224 0.0107 0.0095
Brugia malayi hypothetical protein 0.0218 0.0099 0.0087
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0181 0.0055 0.0473
Echinococcus multilocularis titin 0.0196 0.0073 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.02 0.0601
Echinococcus multilocularis serine:threonine protein kinase N2 0.0666 0.0634 0.124
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0529 0.047 0.1448
Echinococcus multilocularis cyclin dependent kinase 7 0.0684 0.0655 0.1283
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0413 0.127
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0403 0.032 0.0609
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Brugia malayi Cell division protein kinase 2 0.0181 0.0055 0.0043
Schistosoma mansoni protein kinase 0.0282 0.0175 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0422 0.0343 0.0654
Leishmania major casein kinase, putative 0.0356 0.0263 0.2535
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0267 0.2574
Schistosoma mansoni vesicular amine transporter 0.0255 0.0143 0.0424
Brugia malayi protein unc-22 0.0196 0.0073 0.0061
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0338 0.0242 0.2326
Echinococcus granulosus casein kinase I delta 0.0356 0.0263 0.0769
Entamoeba histolytica protein kinase, putative 0.022 0.0101 0.0376
Entamoeba histolytica protein kinase, putative 0.0229 0.0112 0.0416
Entamoeba histolytica PH domain containing protein kinase, putative 0.0884 0.0893 0.3324
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0218 0.0099 0.0087
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.135 0.1448 0.2881
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0351 0.0257 0.0751
Brugia malayi Protein kinase domain containing protein 0.0944 0.0964 0.0953
Entamoeba histolytica cell division protein kinase 2, putative 0.0974 0.1001 0.3727
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0422 0.0343 0.0654
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0917 0.0932 0.9169
Schistosoma mansoni serine/threonine protein kinase 0.07 0.0674 0.2084
Schistosoma mansoni adapter molecule crk 0.0158 0.0027 0.0062
Plasmodium falciparum NIMA related kinase 1 0.0226 0.0108 0.1001
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0508 0.0445 0.0433
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0229 0.0112 0.1035
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Plasmodium falciparum serine/threonine protein kinase KIN 0.0226 0.0108 0.1002
Trichomonas vaginalis STE family protein kinase 0.0428 0.035 0.3395
Entamoeba histolytica protein kinase domain containing protein 0.019 0.0066 0.0245
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Echinococcus multilocularis cyclin dependent kinase 9 0.051 0.0447 0.0864
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0863 0.0868 0.8537
Trichomonas vaginalis CK1 family protein kinase 0.0356 0.0263 0.2535
Entamoeba histolytica protein kinase domain containing protein 0.0181 0.0055 0.0205
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0226 0.0108 0.0097
Echinococcus multilocularis cyclin dependent kinase 5 0.0917 0.0932 0.1842
Echinococcus granulosus tyrosine protein kinase Src42A 0.0422 0.0343 0.1019
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0189 0.0065 0.0147
Echinococcus granulosus serine:threonine protein kinase N2 0.0666 0.0634 0.1932
Schistosoma mansoni ste20-related kinase 0.0837 0.0838 0.2596
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0428 0.035 0.3395
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0482 0.0413 0.0797
Echinococcus multilocularis roundabout 2 0.0363 0.0272 0.0513
Schistosoma mansoni kinase 0.0377 0.0289 0.088
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0108 0.0316
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0255 0.0143 0.0252
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0393 0.0308 0.2979
Trypanosoma cruzi cdc2-related kinase 1 0.0917 0.0932 0.9169
Echinococcus granulosus cyclin dependent kinase 1 0.0917 0.0932 0.2868
Echinococcus multilocularis mitogen activated protein kinase 0.0174 0.0046 0.0058
Echinococcus granulosus serine threonine protein kinase nrc 0.0246 0.0133 0.036
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0241 0.0126 0.0218
Loa Loa (eye worm) hypothetical protein 0.0863 0.0868 0.0857
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0241 0.0127 0.0219
Echinococcus multilocularis tyrosine protein kinase Blk 0.0365 0.0274 0.0517
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0519 0.0458 0.0446
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0964 0.0989 0.9733
Onchocerca volvulus Tyrosine kinase homolog 0.1127 0.1183 0.3582
Entamoeba histolytica casein kinase, putative 0.0356 0.0263 0.098
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0361 0.027 0.0258
Onchocerca volvulus 0.0944 0.0964 0.2887
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.029 0.0185 0.0173
Echinococcus multilocularis cyclin dependent kinase 1 0.0917 0.0932 0.1842
Trypanosoma cruzi polo-like protein kinase, putative 0.0359 0.0267 0.2574
Echinococcus granulosus calcium activated potassium channel 0.0363 0.0272 0.0798
Echinococcus granulosus c src tyrosine kinase 0.0275 0.0167 0.0468
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0181 0.0055 0.0117
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0863 0.0868 0.8537
Brugia malayi Protein kinase c protein 2 0.0253 0.014 0.0129
Echinococcus multilocularis aurora kinase A 0.0351 0.0257 0.0482
Trichomonas vaginalis AGC family protein kinase 0.0351 0.0257 0.2477
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0234 0.0707
Trichomonas vaginalis AGC family protein kinase 0.041 0.0328 0.3181
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0283 0.0177 0.1683
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0229 0.0112 0.0101
Brugia malayi SH2 domain containing protein 0.0218 0.0099 0.0087
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0766 0.0752 0.7383
Leishmania major protein kinase, putative 0.0331 0.0234 0.2243
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0174 0.0046 0.0034
Giardia lamblia Kinase, CMGC CDK 0.0917 0.0932 0.9169
Schistosoma mansoni protein kinase 0.0861 0.0865 0.2682
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0174 0.0046 0.0387
Giardia lamblia Kinase, NEK 0.0226 0.0108 0.1001
Loa Loa (eye worm) TK/ABL protein kinase 0.0423 0.0344 0.0332
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0248 0.0135 0.0368
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0241 0.0127 0.0219
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0112 0.1035
Brugia malayi putative serine/threonine kinase SADA gamma 0.0226 0.0108 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.2823 0.3205 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0226 0.0108 0.0404
Schistosoma mansoni kinase 0.0452 0.0378 0.116
Trichomonas vaginalis CMGC family protein kinase 0.0964 0.0989 0.9733
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0229 0.0112 0.01
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Entamoeba histolytica PH domain containing protein kinase, putative 0.0144 0.0011 0.0039
Trypanosoma cruzi NIMA-related kinase, putative 0.0144 0.0011 0.0031
Brugia malayi Protein kinase domain containing protein 0.0536 0.0478 0.0466
Echinococcus multilocularis casein kinase I alpha 0.0356 0.0263 0.0494
Schistosoma mansoni serine/threonine protein kinase 0.2387 0.2685 0.8374
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0351 0.0257 0.2477
Echinococcus multilocularis 0.0861 0.0865 0.1707
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0331 0.0234 0.0222
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0353 0.0259 0.0758
Brugia malayi SH2 domain containing protein 0.0347 0.0252 0.0241
Giardia lamblia Kinase, CK1 Casein kinase 0.0356 0.0263 0.2535
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0365 0.0274 0.0805
Trichomonas vaginalis STE family protein kinase 0.0241 0.0127 0.1183
Loa Loa (eye worm) hypothetical protein 0.0196 0.0072 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Trichomonas vaginalis STE family protein kinase 0.022 0.0101 0.0928
Onchocerca volvulus 0.0504 0.044 0.1224
Echinococcus granulosus TGF-beta receptor type-1 0.0271 0.0162 0.0453
Schistosoma mansoni serine/threonine protein kinase 0.0766 0.0752 0.2329
Toxoplasma gondii AGC kinase 0.0863 0.0868 0.8537
Echinococcus multilocularis tyrosine protein kinase Srms 0.0365 0.0274 0.0517
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0361 0.027 0.0507
Loa Loa (eye worm) hypothetical protein 0.0268 0.0159 0.0147
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0224 0.0106 0.0396
Schistosoma mansoni vam6/vps39 related 0.0529 0.047 0.1448
Entamoeba histolytica protein kinase , putative 0.0351 0.0257 0.0958
Plasmodium falciparum serine/threonine protein kinase, putative 0.0351 0.0257 0.2477
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0517 0.0456 0.0882
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0353 0.0259 0.0487
Onchocerca volvulus 0.0484 0.0416 0.1148
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0964 0.0989 0.3047
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0241 0.0126 0.0339
Brugia malayi Protein kinase domain containing protein 0.0152 0.0021 0.0009
Echinococcus granulosus mitogen activated protein kinase 11 0.0508 0.0445 0.1339
Echinococcus granulosus tyrosine kinase 0.0365 0.0274 0.0805
Echinococcus multilocularis expressed conserved protein 0.0224 0.0107 0.0179
Schistosoma mansoni tyrosine kinase 0.0422 0.0343 0.1049
Trichomonas vaginalis STE family protein kinase 0.0241 0.0127 0.1183
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0422 0.0343 0.0654
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.019 0.0066 0.0579
Brugia malayi Homeodomain interacting protein kinase protein 1 0.2387 0.2685 0.2676
Trichomonas vaginalis STE family protein kinase 0.0241 0.0127 0.1183
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0766 0.0752 0.7383
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0917 0.0932 0.2868
Echinococcus multilocularis protein KINase family member (kin 25) 0.0248 0.0135 0.0237
Brugia malayi Protein kinase domain containing protein 0.0249 0.0136 0.0124
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0356 0.0263 0.0251
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0987 0.1016 1
Schistosoma mansoni serine/threonine protein kinase 0.079 0.0781 0.2418
Echinococcus granulosus N chimaerin 0.0189 0.0065 0.0147
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0964 0.0989 0.307
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.03 0.0197 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.0301 0.0919
Schistosoma mansoni tyrosine kinase 0.0213 0.0093 0.0269
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0144 0.0011 0.0031
Echinococcus multilocularis serine:threonine protein kinase 3 0.1052 0.1093 0.2166
Schistosoma mansoni serine/threonine protein kinase 0.0519 0.0458 0.1411
Echinococcus granulosus aurora kinase A 0.0351 0.0257 0.0751
Brugia malayi Variant SH3 domain containing protein 0.0158 0.0027 0.0015
Entamoeba histolytica protein kinase, putative 0.0172 0.0044 0.0163
Giardia lamblia Kinase, STE STE20 0.0338 0.0242 0.2326
Entamoeba histolytica protein kinase 2, putative 0.0246 0.0133 0.0494
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0356 0.0263 0.2535
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0246 0.0133 0.1242
Schistosoma mansoni protein kinase 0.0356 0.0263 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.1019 0.1054 0.3273
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0917 0.0932 0.0921
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0224 0.0107 0.0983
Schistosoma mansoni rap gtpase-activating protein 0.0529 0.047 0.1448
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0164 0.0035 0.0271
Entamoeba histolytica protein kinase domain containing protein 0.0964 0.0989 0.3683
Brugia malayi serine/threonine-protein kinase plk-2 0.0359 0.0267 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.2414 0.2717 0.8474
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.074 0.0721 0.2207
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0482 0.0413 0.0402
Echinococcus granulosus casein kinase I alpha 0.0356 0.0263 0.0769
Trichomonas vaginalis STE family protein kinase 0.0226 0.0108 0.1001
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Loa Loa (eye worm) camk/dcamkl protein kinase 0.024 0.0126 0.0114
Trypanosoma cruzi casein kinase, putative 0.0356 0.0263 0.2535
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0174 0.0046 0.0387
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0241 0.0127 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.2405 0.2707 0.8441
Trypanosoma cruzi cdc2-related kinase 1 0.0917 0.0932 0.9169
Schistosoma mansoni tyrosine kinase 0.0475 0.0405 0.1244
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0359 0.0267 0.2574
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Giardia lamblia Kinase, CMGC GSK 0.0964 0.0989 0.9733
Echinococcus granulosus tyrosine protein kinase Fyn 0.0422 0.0343 0.1019
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0667 0.0635 0.0623
Echinococcus granulosus dual specificity 0.0229 0.0112 0.0295
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0172 0.0044 0.0052
Echinococcus multilocularis tyrosine protein kinase shark 0.1103 0.1154 0.2289
Schistosoma mansoni serine/threonine protein kinase 0.079 0.0781 0.2418
Trypanosoma brucei protein kinase, putative 0.0964 0.0989 0.9733
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2414 0.2717 0.2708
Giardia lamblia Kinase, STE STE20 0.0241 0.0127 0.1183
Echinococcus multilocularis c src tyrosine kinase 0.0275 0.0167 0.03
Echinococcus multilocularis insulin receptor 0.0784 0.0774 0.1524
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0158 0.0027 0.0015
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0144 0.0011 0.0032
Echinococcus granulosus serine:threonine kinase SAD 1 0.0226 0.0108 0.0284
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0987 0.1016 1
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.0378 0.116
Entamoeba histolytica p21-activated kinase 0.0261 0.0151 0.0562
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0173 0.0046 0.038
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0403 0.032 0.0949
Loa Loa (eye worm) hypothetical protein 0.0226 0.0108 0.0097
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0254 0.0141 0.0388
Entamoeba histolytica hypothetical protein 0.0377 0.0289 0.1074
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Trichomonas vaginalis CMGC family protein kinase 0.0917 0.0932 0.9169
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0861 0.0865 0.0854
Loa Loa (eye worm) hypothetical protein 0.0458 0.0385 0.0374
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0356 0.0263 0.0251
Echinococcus granulosus casein kinase i 0.0356 0.0263 0.0769
Echinococcus granulosus tyrosine protein kinase Fyn 0.0422 0.0343 0.1019
Loa Loa (eye worm) TK/EPH protein kinase 0.0198 0.0075 0.0063
Giardia lamblia Kinase, CMGC SRPK 0.0173 0.0046 0.038
Brugia malayi Protein kinase domain containing protein 0.0373 0.0284 0.0272
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0331 0.0234 0.2243
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0144 0.0011 0.0031
Plasmodium falciparum calcium-dependent protein kinase 1 0.0331 0.0234 0.2243
Trypanosoma cruzi NIMA-related kinase, putative 0.0144 0.0011 0.0031
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0145 0.0012 0.0046
Loa Loa (eye worm) AUR protein kinase 0.0351 0.0257 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.032 0.0978
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0031 0.0074
Echinococcus multilocularis dual specificity 0.0229 0.0112 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0216 0.0097 0.0887
Entamoeba histolytica protein kinase domain containing protein 0.0229 0.0112 0.0416
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0012 0.0015
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0616 0.0574 0.1744
Leishmania major protein kinase A catalytic subunit isoform 1 0.0863 0.0868 0.8537
Brugia malayi Kinase associated domain 1 family protein 0.024 0.0125 0.0113
Trypanosoma cruzi cdc2-related kinase 3 0.0917 0.0932 0.9169
Brugia malayi Protein kinase domain containing protein 0.0244 0.013 0.0119
Echinococcus granulosus NCK adaptor protein 0.0158 0.0027 0.003
Brugia malayi serine/threonine-protein kinase 6 0.0351 0.0257 0.0245
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0608 0.0564 0.0552
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0387 0.03 0.0289
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0351 0.0257 0.0482
Echinococcus granulosus defective proboscis extension response 0.0255 0.0143 0.0392
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0181 0.0055 0.0473
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0863 0.0868 0.8537
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0112 0.1035
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Giardia lamblia Kinase, AGC AKT 0.0387 0.03 0.2906
Plasmodium falciparum protein serine/threonine kinase-1 0.0987 0.1016 1
Loa Loa (eye worm) hypothetical protein 0.0268 0.0159 0.0147
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.1052 0.1093 0.1083
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0351 0.0257 0.0958
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0267 0.2574
Trichomonas vaginalis AGC family protein kinase 0.0229 0.0112 0.1042
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Brugia malayi Protein kinase domain containing protein 0.0218 0.0099 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0267 0.2574
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.0263 0.0799
Entamoeba histolytica protein kinase, putative 0.0161 0.0031 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0944 0.0964 0.2993
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.135 0.1448 0.4488
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0172 0.0044 0.0361
Toxoplasma gondii aurora kinase 0.0351 0.0257 0.2477
Echinococcus multilocularis CDC7 cell division cycle 7 0.0944 0.0964 0.1907
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0581 0.0532 0.1613
Loa Loa (eye worm) hypothetical protein 0.0423 0.0343 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Brugia malayi cyclin-dependent kinase 7 homolog 0.0742 0.0724 0.0712
Plasmodium vivax serine/threonine kinase-1, putative 0.0987 0.1016 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0265 0.0155 0.0429
Entamoeba histolytica protein kinase, putative 0.0144 0.0011 0.0039
Entamoeba histolytica serine/threonine protein kinase, putative 0.0141 0.0007 0.0027
Giardia lamblia Kinase, CMGC CK2 0.019 0.0066 0.0579
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) hypothetical protein 0.0268 0.0159 0.0147
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0987 0.1016 1
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0244 0.013 0.0353
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Schistosoma mansoni protein kinase 0.135 0.1448 0.4506
Echinococcus multilocularis casein kinase I alpha 0.0356 0.0263 0.0494
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus granulosus casein kinase I gamma 0.0302 0.02 0.057
Schistosoma mansoni tyrosine kinase 0.0275 0.0167 0.0499
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0229 0.0112 0.1035
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0529 0.047 0.4592
Trichomonas vaginalis AGC family protein kinase 0.0373 0.0284 0.2739
Schistosoma mansoni serine/threonine protein kinase 0.0616 0.0574 0.1771
Echinococcus multilocularis casein kinase i 0.0356 0.0263 0.0494
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0536 0.0478 0.0466
Giardia lamblia Kinase, NEK 0.0226 0.0108 0.1001
Plasmodium vivax calcium-dependent protein kinase, putative 0.0331 0.0234 0.2243
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Loa Loa (eye worm) TK/ROR protein kinase 0.0176 0.0049 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Plasmodium falciparum protein kinase, putative 0.0241 0.0126 0.1176
Plasmodium vivax casein kinase 1, putative 0.0356 0.0263 0.2535
Loa Loa (eye worm) hypothetical protein 0.0529 0.047 0.0459
Leishmania major folate/biopterin transporter, putative 0.0144 0.0011 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Brugia malayi Protein kinase domain containing protein 0.0458 0.0385 0.0374
Entamoeba histolytica protein kinase, putative 0.0173 0.0046 0.017
Schistosoma mansoni protein kinase 0.0241 0.0127 0.0373
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0176 0.0049 0.0063
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0331 0.0234 0.0677
Echinococcus granulosus rho-associated protein kinase 1 0.2823 0.3205 1
Echinococcus granulosus neuroglian 0.0314 0.0213 0.0613
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0241 0.0126 0.1176
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0031
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0144 0.0011 0.0032
Entamoeba histolytica protein kinase, putative 0.0351 0.0257 0.0958
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis serine/threonine kinase, putative 0.0181 0.0055 0.0473
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1082 0.1129 0.1118
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0164 0.0034 0.0022
Onchocerca volvulus 0.2024 0.2252 0.6976
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0144 0.0011 0.0031
Brugia malayi Protein kinase domain containing protein 0.0667 0.0635 0.0623
Entamoeba histolytica protein kinase, putative 0.0495 0.043 0.1601
Echinococcus multilocularis cyclin dependent kinase 0.0917 0.0932 0.1842
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0422 0.0343 0.0654
Loa Loa (eye worm) AGC/AKT protein kinase 0.0495 0.043 0.0418
Plasmodium falciparum casein kinase 2, alpha subunit 0.019 0.0066 0.0579
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0917 0.0932 0.0921
Echinococcus multilocularis ephrin type A receptor 4 A 0.0181 0.0054 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0172 0.0044 0.0361
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0144 0.0011 0.0031
Schistosoma mansoni protein kinase C mu 0.0608 0.0564 0.1739
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Entamoeba histolytica protein kinase, putative 0.0161 0.0031 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.0272 0.0828
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.1713
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0241 0.0126 0.1176
Brugia malayi Protein kinase domain containing protein 0.0302 0.02 0.0188
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0244 0.013 0.0119
Echinococcus granulosus tyrosine protein kinase Src64B 0.0422 0.0343 0.1019
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0361 0.027 0.079
Onchocerca volvulus 0.0423 0.0343 0.0916
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0353 0.0259 0.0758
Leishmania major protein kinase, putative 0.0241 0.0126 0.1176
Giardia lamblia Kinase, CDC7 0.0944 0.0964 0.9488
Echinococcus multilocularis dual specificity 0.0229 0.0112 0.0189
Schistosoma mansoni protein kinase 0.0181 0.0055 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0144 0.0011 0.0031
Echinococcus multilocularis mitogen activated protein kinase 11 0.0508 0.0445 0.086
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1019 0.1054 0.1043
Loa Loa (eye worm) AGC/PKA protein kinase 0.0863 0.0868 0.0857
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0529 0.0469 0.0458
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0529 0.047 0.142
Schistosoma mansoni nephrin 0.0327 0.0229 0.0694
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0275 0.0167 0.0499
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0986 0.1014 0.2007
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0234 0.0119 0.0203
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0986 0.1014 0.3126
Echinococcus multilocularis tyrosine kinase 0.0218 0.0099 0.0163
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0331 0.0234 0.2243
Echinococcus multilocularis raf serine:threonine protein kinase 0.0206 0.0084 0.0134
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0241 0.0127 0.0341
Schistosoma mansoni atypical protein kinase C 0.0529 0.047 0.1448
Brugia malayi phosphoinositide-dependent protein kinase I 0.0172 0.0044 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0146 0.0014 0.0002
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0422 0.0343 0.1019
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0863 0.0868 0.8537
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0012 0.0015
Entamoeba histolytica protein kinase, putative 0.0144 0.0011 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Loa Loa (eye worm) AGC/PKG protein kinase 0.0224 0.0107 0.0095
Echinococcus granulosus TGF beta receptor type 1 0.0271 0.0162 0.0453
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0798 0.079 0.2424
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0144 0.0011 0.0032
Entamoeba histolytica hypothetical protein 0.0144 0.0011 0.0039
Loa Loa (eye worm) hypothetical protein 0.0256 0.0144 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0266 0.0157 0.1481
Echinococcus multilocularis rho associated protein kinase 0.2823 0.3205 0.642
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0356 0.0263 0.0251
Brugia malayi serine/threonine protein kinase 6 0.0351 0.0257 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Loa Loa (eye worm) hypothetical protein 0.0423 0.0343 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.2387 0.2685 1
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.032 0.0978
Schistosoma mansoni tyrosine kinase 0.0637 0.0599 0.1849
Schistosoma mansoni protein kinase 0.135 0.1448 0.4506
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0291 0.0186 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0863 0.0868 0.8537
Trichomonas vaginalis CMGC family protein kinase 0.0944 0.0964 0.9488
Loa Loa (eye worm) CDC7 protein kinase 0.0944 0.0964 0.0953
Brugia malayi Protein kinase domain containing protein 0.0784 0.0774 0.0763
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Echinococcus granulosus protein kinase 0.0861 0.0865 0.2658
Entamoeba histolytica PH domain containing protein kinase, putative 0.0266 0.0157 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Brugia malayi map kinase activated protein kinase protein 2 0.0482 0.0413 0.0402
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0055 0.0473
Echinococcus multilocularis mitogen activated protein kinase 14 0.0508 0.0445 0.086
Toxoplasma gondii AGC kinase 0.0475 0.0406 0.3949
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Entamoeba histolytica serine/threonine protein kinase, putative 0.0359 0.0267 0.0994
Echinococcus granulosus serine/threonine protein kinase 0.0266 0.0157 0.0436
Echinococcus granulosus growth factor receptor bound protein 2 0.0163 0.0034 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0422 0.0343 0.1019
Leishmania major protein kinase, putative 0.0144 0.0011 0.0031
Schistosoma mansoni tyrosine kinase 0.0212 0.0092 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.049 0.4781
Brugia malayi Hr1 repeat family protein 0.1019 0.1054 0.1043
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0107 0.031
Onchocerca volvulus 0.0218 0.0099 0.0139
Trypanosoma brucei cdc2-related kinase 3 0.0917 0.0932 0.9169
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0813 0.0809 0.1594
Brugia malayi Casein kinase II, alpha chain 0.019 0.0066 0.0054
Echinococcus multilocularis casein kinase I gamma 0.0302 0.02 0.0366
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Brugia malayi Protein kinase domain containing protein 0.0218 0.0099 0.0087
Brugia malayi Protein kinase domain containing protein 0.1408 0.1518 0.1508
Echinococcus multilocularis transfer RNA-Thr 0.0458 0.0385 0.074
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0226 0.0108 0.1002
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Echinococcus granulosus cGMP dependent protein kinase 1 0.0224 0.0107 0.0278
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0813 0.0809 0.2482
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Trypanosoma cruzi cdc2-related kinase 3 0.0917 0.0932 0.9169
Entamoeba histolytica protein kinase domain containing protein 0.0452 0.0378 0.1408
Brugia malayi Protein kinase domain containing protein 0.0218 0.0099 0.0087
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0265 0.0155 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0112 0.1035
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Plasmodium falciparum calcium-dependent protein kinase 5 0.0331 0.0234 0.2243
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0055 0.0473
Entamoeba histolytica protein kinase, putative 0.0766 0.0752 0.2801
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0413 0.127
Schistosoma mansoni serine/threonine protein kinase 0.0684 0.0655 0.2025
Schistosoma mansoni serine/threonine-protein kinase 0.0266 0.0157 0.0467
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0224 0.0107 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Brugia malayi serine/threonine-protein kinase PAK 7 0.1082 0.1129 0.1118
Brugia malayi p70 ribosomal S6 kinase beta 0.0475 0.0406 0.0394
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0403 0.032 0.0609
Brugia malayi protein kinase C II. 0.0442 0.0367 0.0355
Loa Loa (eye worm) hypothetical protein 0.0255 0.0143 0.0131
Brugia malayi hypothetical protein 0.07 0.0674 0.0662
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0519 0.0458 0.0447
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0917 0.0932 0.0921
Loa Loa (eye worm) TK protein kinase 0.0246 0.0132 0.0121
Onchocerca volvulus 0.2823 0.3205 1
Entamoeba histolytica protein kinase, putative 0.0332 0.0235 0.0875
Onchocerca volvulus 0.0529 0.047 0.132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0331 0.0234 0.0435
Echinococcus multilocularis activated cdc42 kinase 1 0.0458 0.0385 0.074
Schistosoma mansoni tyrosine kinase 0.0475 0.0405 0.1244
Echinococcus multilocularis serine:threonine protein kinase N2 0.1019 0.1054 0.2087
Entamoeba histolytica cell division protein kinase 2, putative 0.0917 0.0932 0.3471
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Plasmodium falciparum calcium-dependent protein kinase 4 0.0331 0.0234 0.2243
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0331 0.0234 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0944 0.0964 0.9488
Echinococcus granulosus tyrosine protein kinase Lyn 0.0546 0.049 0.1481
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0226 0.0108 0.1001
Onchocerca volvulus 0.27 0.3058 0.9533
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0766 0.0752 0.7383
Brugia malayi Protein kinase domain containing protein 0.0917 0.0932 0.0921
Echinococcus granulosus dual specificity 0.0229 0.0112 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0084 0.0241
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0144 0.0011 0.0031
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0519 0.0458 0.0888
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0529 0.047 0.4592
Trichomonas vaginalis AGC family protein kinase 0.0351 0.0257 0.2477
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0246 0.0133 0.1242
Schistosoma mansoni vav2 0.0209 0.0089 0.0254
Trichomonas vaginalis CK1 family protein kinase 0.0356 0.0263 0.2535
Schistosoma mansoni protein kinase 0.0241 0.0126 0.0371
Brugia malayi Protein kinase domain containing protein 0.0254 0.0141 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0863 0.0868 0.2693
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.1713
Schistosoma mansoni tyrosine kinase 0.0517 0.0456 0.1403
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0863 0.0868 0.8537
Plasmodium falciparum calcium-dependent protein kinase 3 0.0331 0.0234 0.2243
Entamoeba histolytica PH domain containing protein kinase, putative 0.0144 0.0011 0.0039
Leishmania major protein kinase, putative 0.0144 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0686 0.0657 0.0646
Brugia malayi Immunoglobulin I-set domain containing protein 0.0268 0.0159 0.0147
Echinococcus multilocularis tyrosine protein kinase HCK 0.0265 0.0155 0.0275
Trypanosoma brucei protein kinase, putative 0.0144 0.0011 0.0031
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0361 0.027 0.0258
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0172 0.0044 0.0032
Loa Loa (eye worm) hypothetical protein 0.0642 0.0605 0.0593
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0176 0.0049 0.0098
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0173 0.0046 0.038
Entamoeba histolytica protein kinase domain containing protein 0.0241 0.0126 0.0469
Trypanosoma cruzi aurora B kinase, putative 0.0351 0.0257 0.2477
Schistosoma mansoni protein kinase 0.019 0.0066 0.0183
Echinococcus granulosus mitogen activated protein kinase 14 0.0508 0.0445 0.1339
Schistosoma mansoni protein kinase 0.0241 0.0126 0.0371
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0144 0.0011 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0863 0.0868 0.2693
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.2387 0.2685 0.2676
Schistosoma mansoni tyrosine kinase 0.0592 0.0545 0.1681
Brugia malayi Immunoglobulin I-set domain containing protein 0.0196 0.0073 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Plasmodium vivax unspecified product 0.019 0.0066 0.0579
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0034 0.0268
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0964 0.0989 0.1956
Loa Loa (eye worm) hypothetical protein 0.0158 0.0027 0.0015
Loa Loa (eye worm) hypothetical protein 0.0793 0.0785 0.0774
Loa Loa (eye worm) SRC-1 0.0422 0.0343 0.0331
Echinococcus multilocularis protein kinase shaggy 0.0964 0.0989 0.1956
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0181 0.0055 0.0473
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0616 0.0574 0.0562
Giardia lamblia Kinase, CAMK CAMKL 0.0283 0.0177 0.1683
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0917 0.0932 0.9169
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0226 0.0108 0.1002
Echinococcus granulosus homeodomain interacting protein kinase 3 0.2387 0.2685 0.8369
Echinococcus multilocularis TGF beta receptor type 1 0.0271 0.0162 0.0291
Entamoeba histolytica protein kinase domain containing protein 0.0351 0.0257 0.0958
Trypanosoma brucei SNF1-related protein kinases, putative 0.0226 0.0108 0.1002
Brugia malayi Sex muscle abnormal protein 5 0.0158 0.0027 0.0015
Echinococcus granulosus roundabout 2 0.0363 0.0272 0.0799
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0173 0.0046 0.038
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0508 0.0445 0.4335
Giardia lamblia Kinase, NEK 0.0226 0.0108 0.1001
Trypanosoma brucei Casein kinase II 0.019 0.0066 0.0579
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.017 0.5
Brugia malayi SRC-1 0.0422 0.0343 0.0331
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0863 0.0868 0.8537
Schistosoma mansoni serine/threonine kinase 0.0353 0.0259 0.0788
Schistosoma mansoni tyrosine kinase 0.0761 0.0747 0.2313
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0359 0.0267 0.0502
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0581 0.0532 0.1036
Echinococcus multilocularis death associated protein kinase 1 0.4314 0.4982 1
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) hypothetical protein 0.0341 0.0246 0.0234
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0508 0.0445 0.4335
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0173 0.0046 0.038
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0226 0.0108 0.0182
Echinococcus multilocularis PAK box P21 Rho binding 0.022 0.0101 0.0168
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0161 0.0031 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0917 0.0932 0.9169
Brugia malayi Protein kinase domain containing protein 0.029 0.0185 0.0173
Echinococcus multilocularis calcium activated potassium channel 0.0363 0.0272 0.0512
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.0257 0.0781
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0653 0.0618 0.1208
Schistosoma mansoni tyrosine kinase 0.0784 0.0774 0.2399
Brugia malayi Protein kinase domain containing protein 0.0282 0.0175 0.0164
Loa Loa (eye worm) hypothetical protein 0.0164 0.0034 0.0022
Onchocerca volvulus 0.0218 0.0099 0.0139
Trypanosoma brucei casein kinase I, isoform 2 0.0356 0.0263 0.2535
Echinococcus multilocularis mitogen activated protein kinase 3 0.0174 0.0046 0.0058
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0422 0.0343 0.0654
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0347 0.0252 0.0472
Echinococcus granulosus calcium dependent protein kinase 0.0207 0.0086 0.0215
Schistosoma mansoni tyrosine kinase 0.0275 0.0167 0.0499
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0055 0.0473
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0413 0.127
Brugia malayi Protein kinase domain containing protein 0.0173 0.0046 0.0034
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0174 0.0046 0.0387
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0359 0.0267 0.0255
Brugia malayi Protein kinase domain containing protein 0.0785 0.0775 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.0353 0.0259 0.0788
Brugia malayi Protein kinase domain containing protein 0.0181 0.0055 0.0043
Echinococcus multilocularis dual specificity 0.0229 0.0112 0.0189
Plasmodium falciparum protein kinase 5 0.0917 0.0932 0.9169
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0373 0.0284 0.0272
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0249 0.0136 0.0124
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0331 0.0234 0.2243
Giardia lamblia Kinase, CMGC GSK 0.0964 0.0989 0.9733
Giardia lamblia Kinase, CMGC DYRK 0.0229 0.0112 0.1035
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.1713
Schistosoma mansoni protein kinase 0.135 0.1448 0.4506
Giardia lamblia Kinase, CMGC MAPK 0.0174 0.0046 0.0387
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0353 0.0259 0.0487
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0229 0.0112 0.01
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0189 0.0065 0.0053
Onchocerca volvulus 0.0951 0.0973 0.2915
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0158 0.0027 0.0062
Loa Loa (eye worm) TK protein kinase 0.0265 0.0155 0.0143
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0331 0.0234 0.0435
Echinococcus granulosus cGMP dependent protein kinase 1 0.0224 0.0107 0.0278
Brugia malayi protein-tyrosine kinase 0.0365 0.0274 0.0263
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0686 0.0657 0.0646
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Brugia malayi Immunoglobulin I-set domain containing protein 0.0576 0.0526 0.0515
Echinococcus granulosus twitchin 0.0437 0.036 0.1075
Schistosoma mansoni tyrosine kinase 0.1103 0.1154 0.3586
Echinococcus granulosus tyrosine protein kinase Srms 0.0622 0.0581 0.1766
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0241 0.0127 0.0219
Schistosoma mansoni protein kinase 0.0271 0.0162 0.0484
Echinococcus multilocularis serine:threonine protein kinase 0.0164 0.0034 0.0033
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0241 0.0126 0.1176
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0173 0.0046 0.0034
Brugia malayi Protein kinase domain containing protein 0.0686 0.0657 0.0646
Echinococcus granulosus dual specificity mitogen activated protein 0.0428 0.035 0.1041
Echinococcus granulosus tyrosine protein kinase Src42A 0.0253 0.0141 0.0387
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0828 0.0826 0.1629
Echinococcus multilocularis hypothetical protein 0.024 0.0125 0.0216
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0331 0.0234 0.2243
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0232 0.0116 0.1075
Brugia malayi probable protein kinase 0.139 0.1496 0.1486
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0144 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.035 0.0257 0.0245
Brugia malayi MAP kinase sur-1 0.0174 0.0046 0.0034
Schistosoma mansoni tyrosine kinase 0.0248 0.0135 0.04
Loa Loa (eye worm) hypothetical protein 0.0423 0.0343 0.0332
Echinococcus multilocularis mitogen activated protein kinase 14 0.0508 0.0445 0.086
Onchocerca volvulus 0.0218 0.0099 0.0139
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0508 0.0445 0.4335
Trypanosoma brucei aurora B kinase 0.0351 0.0257 0.2477
Plasmodium falciparum calcium-dependent protein kinase 2 0.0331 0.0234 0.2243
Echinococcus granulosus serine:threonine protein kinase 0.0164 0.0034 0.0052
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0171 0.0043 0.0355
Schistosoma mansoni tyrosine kinase 0.0422 0.0343 0.1049
Echinococcus granulosus fibroblast growth factor receptor 4 0.0517 0.0456 0.1374
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0246 0.0133 0.1242
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0331 0.0234 0.2243
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0108 0.1002
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2414 0.2717 0.8469
Echinococcus multilocularis 0.0208 0.0087 0.0139
Loa Loa (eye worm) TK/FAK protein kinase 0.0643 0.0606 0.0595
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.079 0.0781 0.1537
Brugia malayi Protein kinase domain containing protein 0.2024 0.2252 0.2243
Echinococcus granulosus protein kinase c iota type 0.0523 0.0463 0.1397
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Echinococcus granulosus cyclin dependent kinase 5 0.0917 0.0932 0.2868
Entamoeba histolytica casein kinase 1, putative 0.0356 0.0263 0.098
Schistosoma mansoni tyrosine kinase 0.0475 0.0405 0.1244
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0254 0.0141 0.0249
Loa Loa (eye worm) hypothetical protein 0.0458 0.0385 0.0373
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0351 0.0257 0.2477
Brugia malayi hypothetical protein 0.0268 0.0159 0.0147
Echinococcus multilocularis activin receptor type 0.0994 0.1024 0.2026
Entamoeba histolytica protein kinase, putative 0.0351 0.0257 0.0958
Brugia malayi Tyrosine-protein kinase abl-1 0.0354 0.0261 0.0249
Trichomonas vaginalis AGC family protein kinase 0.0495 0.043 0.4189
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0055 0.0473
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0863 0.0868 0.0857
Echinococcus multilocularis serine:threonine protein kinase 0.0164 0.0034 0.0033
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0164 0.0035 0.0271
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0529 0.047 0.0912
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0032
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0244 0.013 0.0227
Giardia lamblia Kinase, AGC PKA 0.0863 0.0868 0.8537
Brugia malayi Protein kinase domain containing protein 0.0218 0.0099 0.0087
Echinococcus granulosus casein kinase I alpha 0.0356 0.0263 0.0769
Echinococcus granulosus Vam6:Vps39 protein 0.0529 0.047 0.142
Onchocerca volvulus 0.0395 0.0311 0.0813
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0766 0.0752 0.7383
Echinococcus granulosus Immunoglobulin 0.0255 0.0143 0.0392
Loa Loa (eye worm) hypothetical protein 0.0642 0.0605 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0359 0.0267 0.2574
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0546 0.049 0.148
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0099 0.0087
Brugia malayi Protein kinase domain containing protein 0.0407 0.0324 0.0313
Entamoeba histolytica protein kinase, putative 0.0265 0.0155 0.0575
Onchocerca volvulus 0.0964 0.0989 0.2966
Schistosoma mansoni protein kinase 0.0241 0.0126 0.0371
Brugia malayi Protein kinase domain containing protein 0.0495 0.043 0.0418
Schistosoma mansoni hypothetical protein 0.024 0.0125 0.0368
Trypanosoma brucei rac serine-threonine kinase, putative 0.0495 0.043 0.4189
Brugia malayi Variant SH3 domain containing protein 0.0158 0.0027 0.0015
Echinococcus multilocularis casein kinase I delta 0.0356 0.0263 0.0494
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0331 0.0234 0.0222
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0616 0.0574 0.1119
Plasmodium vivax serine/threonine protein kinase, putative 0.0173 0.0046 0.038
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0422 0.0343 0.0654
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0174 0.0046 0.0387
Loa Loa (eye worm) hypothetical protein 0.0229 0.0113 0.0101
Brugia malayi protein kinase C3,putative 0.0294 0.019 0.0178
Giardia lamblia Kinase, CAMK CAMKL 0.0181 0.0055 0.0473
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1936 0.2147 0.668
Plasmodium vivax glycogen synthase kinase 3, putative 0.0964 0.0989 0.9733
Loa Loa (eye worm) hypothetical protein 0.1204 0.1275 0.1264
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0018 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Schistosoma mansoni protein kinase 0.0351 0.0257 0.0781
Echinococcus granulosus expressed protein 0.0173 0.0046 0.0087
Schistosoma mansoni hypothetical protein 0.0529 0.047 0.1448
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0035 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0185 0.0555
Leishmania major protein kinase, putative 0.0338 0.0242 0.2326
Toxoplasma gondii protein kinase domain-containing protein 0.0144 0.0011 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0011 0.0031
Echinococcus granulosus dual specificity 0.0229 0.0112 0.0295
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0863 0.0868 0.1713
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0066 0.0579
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0863 0.0868 0.8537
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0519 0.0458 0.1382
Echinococcus granulosus cyclin dependent kinase 19 0.0667 0.0635 0.1935
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0351 0.0257 0.0958
Brugia malayi Protein kinase domain containing protein 0.0353 0.0259 0.0248
Plasmodium falciparum serine/threonine protein kinase 0.0173 0.0046 0.038
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0255 0.0143 0.0424
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0181 0.0055 0.0075
Trypanosoma cruzi p21-activated kinase 3, putative 0.0145 0.0012 0.0046
Entamoeba histolytica PH domain containing protein kinase, putative 0.0266 0.0157 0.0584
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0246 0.0133 0.0231
Brugia malayi bone morphogenetic protein type 1 receptor 0.0265 0.0155 0.0143
Loa Loa (eye worm) haspin protein kinase 0.0181 0.0055 0.0043
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0144 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.035 0.0257 0.0245
Giardia lamblia Aurora kinase 0.0351 0.0257 0.2477
Loa Loa (eye worm) hypothetical protein 0.0484 0.0416 0.0405
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0608 0.0564 0.0552
Loa Loa (eye worm) hypothetical protein 0.0504 0.044 0.0429
Schistosoma mansoni growth factor receptor-bound protein 0.0158 0.0027 0.0062
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0351 0.0257 0.0958
Echinococcus granulosus protein kinase c epsilon type 0.0442 0.0367 0.1094
Brugia malayi RhoGAP domain containing protein 0.0189 0.0065 0.0053
Schistosoma mansoni hypothetical protein 0.024 0.0125 0.0368
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.074 0.0721 0.1417
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0055 0.0473
Loa Loa (eye worm) hypothetical protein 0.0331 0.0234 0.0222
Echinococcus multilocularis growth factor receptor bound protein 2 0.0158 0.0027 0.0019
Loa Loa (eye worm) hypothetical protein 0.0395 0.0311 0.0299
Echinococcus granulosus mitogen activated protein kinase 3 0.0174 0.0046 0.009
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0171 0.0043 0.0355
Trypanosoma brucei polo-like protein kinase 0.0359 0.0267 0.2574
Brugia malayi hypothetical protein 0.0529 0.047 0.0459

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0014 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.4654 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 23.9341 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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