Detailed information for compound 1356694

Basic information

Technical information
  • TDR Targets ID: 1356694
  • Name: 2-[(4-ethyl-5-furan-2-yl-1,2,4-triazol-3-yl)s ulfanyl]-1-thiophen-2-ylethanone
  • MW: 319.402 | Formula: C14H13N3O2S2
  • H donors: 0 H acceptors: 3 LogP: 2.76 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCn1c(SCC(=O)c2cccs2)nnc1c1ccco1
  • InChi: 1S/C14H13N3O2S2/c1-2-17-13(11-5-3-7-19-11)15-16-14(17)21-9-10(18)12-6-4-8-20-12/h3-8H,2,9H2,1H3
  • InChiKey: UVIRHXQHFGBHNA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[4-ethyl-5-(2-furyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thienyl)ethanone
  • 2-[[4-ethyl-5-(2-furyl)-1,2,4-triazol-3-yl]thio]-1-(2-thienyl)ethanone
  • 2-[(4-ethyl-5-furan-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-thiophen-2-yl-ethanone
  • ZINC00410331
  • 2-(4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-thiophen-2-yl-ethanone
  • ASN 06164300
  • SMR000006145
  • MLS000073511

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis titin 0.0721 0.0274 0.0273
Echinococcus multilocularis tyrosine protein kinase otk 0.053 0.0098 0.0097
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0809 0.0355 0.0373
Brugia malayi Protein kinase domain containing protein 0.1255 0.0766 0.0807
Trichomonas vaginalis CMGC family protein kinase 0.0608 0.0169 0.1005
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.175 0.1223 0.1287
Trichomonas vaginalis CMGC family protein kinase 0.1112 0.0634 0.3766
Loa Loa (eye worm) hypothetical protein 0.2412 0.1833 0.193
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0509 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0864 0.0405 0.0427
Trypanosoma brucei SNF1-related protein kinases, putative 0.0839 0.0383 0.1686
Brugia malayi map kinase activated protein kinase protein 2 0.2199 0.1637 0.1724
Loa Loa (eye worm) gastrulation defective protein 1 0.1769 0.124 0.1306
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Entamoeba histolytica hypothetical protein 0.0464 0.0037 0.0026
Echinococcus granulosus integrin linked protein kinase 0.0458 0.0031 0.0034
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0428 0.0003 0.0018
Schistosoma mansoni serine/threonine kinase 0.1213 0.0728 0.2105
Schistosoma mansoni protein kinase 0.1098 0.0621 0.1797
Trichomonas vaginalis TKL family protein kinase 0.0464 0.0037 0.0218
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Echinococcus multilocularis casein kinase i 0.1098 0.0621 0.062
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Trypanosoma cruzi rac serine-threonine kinase, putative 0.1032 0.0561 0.2652
Brugia malayi Protein kinase domain containing protein 0.1284 0.0792 0.0834
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1136 0.0656 0.0691
Echinococcus granulosus tyrosine protein kinase HCK 0.1159 0.0677 0.0755
Brugia malayi Prion-like- 0.053 0.0098 0.0103
Echinococcus multilocularis cyclin dependent kinase 9 0.0726 0.0278 0.0277
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.1472 0.0966 0.4568
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0565 0.0129 0.0128
Trichomonas vaginalis STE family protein kinase 0.0717 0.027 0.1603
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.1213 0.0728 0.2105
Loa Loa (eye worm) hypothetical protein 0.2001 0.1454 0.1531
Leishmania major protein kinase, putative 0.2251 0.1684 0.7935
Echinococcus granulosus lachesin 0.053 0.0098 0.0108
Schistosoma mansoni septate junction protein 0.053 0.0098 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.3255 0.2611 0.7555
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0624 0.0184 0.0534
Brugia malayi Fes/CIP4 homology domain containing protein 0.0688 0.0243 0.0256
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1012 0.0542 0.0541
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Echinococcus granulosus retinal guanylyl cyclase 2 0.0458 0.0031 0.0034
Brugia malayi Tyrosine-protein kinase PR2 0.0458 0.0031 0.0033
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0958 0.0492 0.2787
Trichomonas vaginalis AGC family protein kinase 0.0637 0.0196 0.1166
Loa Loa (eye worm) TK/FAK protein kinase 0.3645 0.297 0.3127
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1129 0.065 0.0725
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Brugia malayi hypothetical protein 0.0441 0.0015 0.0016
Plasmodium vivax protein kinase, putative 0.0537 0.0104 0.044
Trichomonas vaginalis STE family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.3255 0.2611 0.261
Brugia malayi Hr1 repeat family protein 0.1891 0.1352 0.1424
Trichomonas vaginalis CAMK family protein kinase 0.1551 0.1039 0.6171
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.1363 0.0866 0.0912
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.2522 0.1934 0.1933
Trichomonas vaginalis CMGC family protein kinase 0.1112 0.0634 0.3766
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1695 0.1171 0.5473
Brugia malayi cyclin-dependent kinase 9 0.0726 0.0278 0.0293
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0839 0.0383 0.0403
Schistosoma mansoni serine/threonine protein kinase 0.1198 0.0713 0.2064
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.3632 0.2959 0.3231
Echinococcus multilocularis cyclin dependent kinase 1 0.1112 0.0634 0.0633
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1012 0.0542 0.0541
Onchocerca volvulus 0.3346 0.2694 0.2941
Loa Loa (eye worm) hypothetical protein 0.1249 0.0761 0.0801
Echinococcus granulosus activated cdc42 kinase 1 0.2524 0.1936 0.2162
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0576 0.014 0.0523
Brugia malayi Protein kinase domain containing protein 0.3634 0.296 0.3117
Brugia malayi hypothetical protein 0.0528 0.0096 0.0101
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.1168 0.0686 0.1986
Loa Loa (eye worm) hypothetical protein 0.0738 0.029 0.0305
Brugia malayi Homeodomain interacting protein kinase protein 1 0.1198 0.0713 0.0751
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus granulosus tyrosine protein kinase csk 0.0458 0.0031 0.0034
Plasmodium falciparum casein kinase 1 0.1098 0.0621 0.3567
Loa Loa (eye worm) protein kinase domain-containing protein 0.1253 0.0764 0.0805
Trichomonas vaginalis CMGC family protein kinase 0.0608 0.0169 0.1005
Trichomonas vaginalis CAMK family protein kinase 0.1551 0.1039 0.6171
Schistosoma mansoni vav2 0.0831 0.0375 0.1085
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.2199 0.1637 0.1636
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Echinococcus granulosus serine threonine protein kinase nrc 0.0957 0.0492 0.0548
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi Protein kinase domain containing protein 0.2717 0.2114 0.2227
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.0098 0.0103
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.1644 0.1125 0.5248
Entamoeba histolytica protein kinase domain containing protein 0.0769 0.0318 0.1377
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0775 0.0323 0.0322
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0775 0.0323 0.0359
Echinococcus multilocularis neuroglian 0.1486 0.0979 0.0978
Loa Loa (eye worm) TK protein kinase 0.1159 0.0677 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.1891 0.1352 0.3914
Loa Loa (eye worm) TK/KIN16 protein kinase 0.7079 0.6137 0.6463
Trichomonas vaginalis CMGC family protein kinase 0.1199 0.0714 0.4239
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.1098 0.0621 0.0654
Entamoeba histolytica protein kinase domain containing protein 0.0551 0.0116 0.0408
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.2251 0.1684 0.7966
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0458 0.0031 0.0018
Loa Loa (eye worm) TK/ABL protein kinase 0.3416 0.2759 0.2905
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi Protein kinase domain containing protein 0.0864 0.0405 0.0427
Echinococcus granulosus c src tyrosine kinase 0.1168 0.0686 0.0765
Loa Loa (eye worm) hypothetical protein 0.117 0.0687 0.0724
Schistosoma mansoni serine/threonine protein kinase 0.1018 0.0548 0.1585
Loa Loa (eye worm) hypothetical protein 0.0426 0.0001 0.0001
Toxoplasma gondii CMGC kinase, CK2 family 0.0662 0.0219 0.1136
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.2717 0.2114 1
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Schistosoma mansoni serine/threonine protein kinase 0.0509 0.0078 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.1624 0.1106 0.6569
Echinococcus multilocularis cyclin dependent kinase 0.1112 0.0634 0.0633
Schistosoma mansoni tyrosine kinase 0.3607 0.2935 0.8494
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0458 0.0031 0.0033
Brugia malayi Protein kinase domain 0.0717 0.027 0.0284
Loa Loa (eye worm) hypothetical protein 0.1249 0.0761 0.0801
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Brugia malayi Protein kinase domain containing protein 0.0864 0.0405 0.0427
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.2339 0.1766 0.1859
Trichomonas vaginalis STE family protein kinase 0.1916 0.1375 0.8166
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0842 0.0385 0.0384
Loa Loa (eye worm) hypothetical protein 0.071 0.0263 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.4172 0.3456 1
Brugia malayi hypothetical protein 0.3255 0.2611 0.2749
Brugia malayi SH2 domain containing protein 0.1129 0.065 0.0684
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0896 0.0435 0.0484
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni hypothetical protein 0.0494 0.0064 0.0185
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0581 0.0145 0.0544
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1916 0.1375 0.1448
Schistosoma mansoni serine/threonine protein kinase 0.1012 0.0542 0.1569
Echinococcus granulosus cGMP dependent protein kinase 1 0.0842 0.0385 0.0429
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0932 0.0468 0.0521
Leishmania major protein kinase, putative 0.0769 0.0318 0.1377
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.1255 0.0766 0.0807
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0573 0.0137 0.0144
Trichomonas vaginalis STE family protein kinase 0.0958 0.0492 0.2921
Toxoplasma gondii AGC kinase 0.1472 0.0966 0.5654
Brugia malayi Serine/threonine-protein kinase SULU 0.3255 0.2611 0.2749
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0809 0.0355 0.0373
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0458 0.0031 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.3632 0.2959 0.8561
Schistosoma mansoni hypothetical protein 0.0535 0.0102 0.0295
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Onchocerca volvulus Tyrosine kinase homolog 0.6011 0.5152 0.5639
Echinococcus multilocularis epidermal growth factor receptor 0.2807 0.2197 0.2196
Loa Loa (eye worm) TK/RYK protein kinase 0.0458 0.0031 0.0033
Entamoeba histolytica protein kinase, putative 0.1935 0.1393 0.6535
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1869 0.1332 0.1331
Echinococcus multilocularis TGF beta receptor type 1 0.1278 0.0787 0.0786
Entamoeba histolytica protein kinase domain containing protein 0.2717 0.2114 1
Schistosoma mansoni titin 0.053 0.0098 0.0283
Giardia lamblia Kinase, CMGC GSK 0.1199 0.0714 0.4129
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0576 0.014 0.0148
Schistosoma mansoni ephrin receptor 0.0793 0.034 0.0984
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.117 0.0687 0.1989
Toxoplasma gondii histone kinase SNF1, putative 0.0839 0.0383 0.2125
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.1472 0.0966 0.5654
Brugia malayi Protein kinase domain containing protein 0.2483 0.1899 0.1999
Brugia malayi Stress-activated protein kinase jnk-1 0.4172 0.3456 0.3639
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0458 0.0031 0.0186
Plasmodium falciparum cGMP-dependent protein kinase 0.0842 0.0385 0.2142
Echinococcus granulosus tyrosine kinase 0.0458 0.0031 0.0034
Brugia malayi Protein kinase domain containing protein 0.1363 0.0866 0.0912
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus tyrosine protein kinase otk 0.053 0.0098 0.0108
Giardia lamblia Kinase, CMGC CDK 0.1112 0.0634 0.3647
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1136 0.0656 0.0655
Onchocerca volvulus 1.0318 0.9124 1
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0458 0.0031 0.0033
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0957 0.0492 0.2784
Loa Loa (eye worm) hypothetical protein 0.0801 0.0347 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0996 0.0528 0.1526
Echinococcus multilocularis mitogen activated protein kinase 11 0.213 0.1573 0.1572
Echinococcus multilocularis activated cdc42 kinase 1 0.2524 0.1936 0.1935
Onchocerca volvulus 0.3657 0.2981 0.3256
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.1018 0.0548 0.0577
Echinococcus multilocularis roundabout 2 0.1794 0.1263 0.1262
Trichomonas vaginalis AGC family protein kinase 0.1255 0.0766 0.4548
Echinococcus multilocularis c Jun NH2 terminal kinase 0.4172 0.3456 0.3455
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0756 0.0306 0.0305
Loa Loa (eye worm) hypothetical protein 0.053 0.0098 0.0103
Echinococcus multilocularis tyrosine protein kinase csk 0.0458 0.0031 0.003
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Onchocerca volvulus Netrin receptor homolog 0.0467 0.0039 0.0027
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.194 0.1397 0.1472
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1012 0.0542 0.0604
Trichomonas vaginalis STE family protein kinase 0.0717 0.027 0.1603
Trypanosoma cruzi Protein kinase B 0.1032 0.0561 0.2652
Schistosoma mansoni tyrosine kinase 0.2807 0.2197 0.6357
Brugia malayi Immunoglobulin I-set domain containing protein 0.0721 0.0274 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0839 0.0383 0.1107
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.2199 0.1637 0.1724
Echinococcus granulosus tyrosine protein kinase csk 0.0458 0.0031 0.0034
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.1278 0.0787 0.0786
Plasmodium vivax tyrosine kinase-like protein, putative 0.0562 0.0127 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.0043 0.0124
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.1644 0.1125 0.5248
Brugia malayi Egg laying defective protein 4 0.0842 0.0385 0.0406
Echinococcus multilocularis mitogen activated protein kinase 11 0.213 0.1573 0.1572
Brugia malayi Protein kinase domain containing protein 0.3408 0.2752 0.2898
Echinococcus multilocularis MAM 0.0441 0.0015 0.0014
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.1012 0.0542 0.3091
Schistosoma mansoni tyrosine kinase 0.2807 0.2197 0.6357
Giardia lamblia Aurora kinase 0.1644 0.1125 0.6614
Schistosoma mansoni hypothetical protein 0.1025 0.0554 0.1603
Trichomonas vaginalis CAMK family protein kinase 0.0799 0.0346 0.2053
Trichomonas vaginalis AGC family protein kinase 0.1644 0.1125 0.6677
Loa Loa (eye worm) TK protein kinase 0.0458 0.0031 0.0033
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.2483 0.1899 0.1999
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0458 0.0031 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.194 0.1398 0.4046
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0756 0.0306 0.0885
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.053 0.0098 0.0283
Brugia malayi Immunoglobulin I-set domain containing protein 0.0624 0.0184 0.0194
Echinococcus granulosus dual specificity 0.0809 0.0355 0.0395
Trichomonas vaginalis CAMK family protein kinase 0.0738 0.029 0.172
Giardia lamblia Kinase, NEK 0.0958 0.0492 0.2787
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.1472 0.0966 0.5654
Schistosoma mansoni serine/threonine protein kinase 0.194 0.1398 0.4046
Echinococcus granulosus fibroblast growth factor receptor 4 0.2519 0.1931 0.2156
Loa Loa (eye worm) CAMK protein kinase 0.0721 0.0274 0.0288
Echinococcus multilocularis myosin iiia 0.0581 0.0145 0.0143
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.1472 0.0966 0.4568
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.3728 0.3047 0.3046
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.074 0.0291 0.029
Schistosoma mansoni serine/threonine protein kinase 0.1018 0.0548 0.1585
Loa Loa (eye worm) TK protein kinase 0.0724 0.0276 0.0291
Loa Loa (eye worm) sex muscle abnormal protein 5 0.071 0.0263 0.0277
Echinococcus granulosus TGF beta receptor type 1 0.1278 0.0787 0.0878
Trypanosoma cruzi protein kinase, putative 0.0458 0.0031 0.0148
Echinococcus granulosus kinase suppressor of Ras 1 0.0458 0.0031 0.0034
Echinococcus multilocularis twitchin 0.0627 0.0187 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.053 0.0098 0.0097
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0458 0.0031 0.0186
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0996 0.0528 0.0526
Brugia malayi RhoGAP domain containing protein 0.0756 0.0306 0.0322
Echinococcus multilocularis protein tyrosine kinase 0.3607 0.2935 0.2934
Trypanosoma cruzi aurora B kinase, putative 0.1644 0.1125 0.5318
Schistosoma mansoni protein kinase 0.0717 0.027 0.0781
Echinococcus granulosus roundabout 2 0.0624 0.0184 0.0205
Onchocerca volvulus Serine\/threonine kinase homolog 0.0996 0.0528 0.0563
Loa Loa (eye worm) hypothetical protein 0.2001 0.1454 0.1531
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.2522 0.1934 0.2037
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.0098 0.0103
Echinococcus multilocularis protein kinase shaggy 0.1199 0.0714 0.0713
Entamoeba histolytica protein kinase, putative 0.0604 0.0165 0.0644
Loa Loa (eye worm) CAMK/PKD protein kinase 0.156 0.1047 0.1103
Echinococcus multilocularis serine:threonine protein kinase 3 0.1481 0.0975 0.0973
Trichomonas vaginalis STE family protein kinase 0.0604 0.0165 0.0982
Schistosoma mansoni serine/threonine RGC 0.0458 0.0031 0.0091
Entamoeba histolytica PH domain containing protein kinase, putative 0.1547 0.1035 0.4818
Onchocerca volvulus 0.0864 0.0405 0.0428
Trichomonas vaginalis CAMK family protein kinase 0.1551 0.1039 0.6171
Echinococcus granulosus Vam6:Vps39 protein 0.1025 0.0554 0.0618
Loa Loa (eye worm) IKK protein kinase 1.0318 0.9124 0.9609
Echinococcus granulosus mitogen activated protein kinase 0.0576 0.014 0.0155
Entamoeba histolytica PH domain containing protein kinase, putative 0.1032 0.0561 0.2541
Schistosoma mansoni serine/threonine protein kinase 0.0846 0.0389 0.1125
Schistosoma mansoni protein tyrosine kinase 0.0458 0.0031 0.0091
Loa Loa (eye worm) protein kinase domain-containing protein 0.0458 0.0031 0.0033
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0458 0.0031 0.0091
Schistosoma mansoni tyrosine kinase 0.1168 0.0686 0.1986
Trichomonas vaginalis AGC family protein kinase 0.1644 0.1125 0.6677
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0565 0.0129 0.0768
Plasmodium falciparum protein kinase, putative 0.0769 0.0318 0.1736
Leishmania major protein kinase A catalytic subunit isoform 1 0.1472 0.0966 0.4487
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Brugia malayi protein unc-22 0.0721 0.0274 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0576 0.014 0.0406
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0458 0.0031 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0726 0.0278 0.0804
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.1041 0.0569 0.0568
Brugia malayi plexin A 0.0438 0.0013 0.0014
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Schistosoma mansoni protein kinase 0.1644 0.1125 0.3254
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0581 0.0145 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Plasmodium vivax calcium-dependent protein kinase, putative 0.1012 0.0542 0.3091
Onchocerca volvulus 0.1025 0.0554 0.0592
Plasmodium vivax serine/threonine protein kinase 6, putative 0.1644 0.1125 0.6614
Echinococcus multilocularis dual specificity 0.0809 0.0355 0.0353
Trypanosoma brucei cdc2-related kinase 3 0.1112 0.0634 0.2894
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1778 0.1248 0.1247
Schistosoma mansoni serine/threonine protein kinase 0.1213 0.0728 0.2105
Brugia malayi cell division control protein 2 homolog 0.1112 0.0634 0.0668
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1336 0.0841 0.0938
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1199 0.0714 0.0796
Echinococcus multilocularis plexin a4 0.0438 0.0013 0.0012
Echinococcus granulosus TGF-beta receptor type-1 0.1278 0.0787 0.0878
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1551 0.1039 0.4839
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0458 0.0031 0.0091
Echinococcus granulosus nervana 2 0.0646 0.0205 0.0227
Entamoeba histolytica protein kinase, putative 0.0679 0.0235 0.0976
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0809 0.0355 0.1677
Onchocerca volvulus 0.0864 0.0405 0.0428
Echinococcus multilocularis transfer RNA-Thr 0.2524 0.1936 0.1935
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Onchocerca volvulus Basement membrane proteoglycan homolog 0.053 0.0098 0.0091
Echinococcus multilocularis G protein coupled receptor kinase 6 0.175 0.1223 0.1221
Loa Loa (eye worm) hypothetical protein 0.0624 0.0184 0.0194
Loa Loa (eye worm) hypothetical protein 0.1025 0.0554 0.0583
Onchocerca volvulus 0.0864 0.0405 0.0428
Plasmodium falciparum glycogen synthase kinase 3 0.1199 0.0714 0.4129
Echinococcus granulosus cyclin dependent kinase 19 0.208 0.1527 0.1705
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0576 0.014 0.0663
Brugia malayi Kinase associated domain 1 family protein 0.0535 0.0102 0.0107
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.2251 0.1684 0.7966
Schistosoma mansoni growth factor receptor-bound protein 0.071 0.0263 0.0762
Brugia malayi Raf kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis epidermal growth factor receptor 0.3895 0.32 0.3199
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.053 0.0098 0.0103
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0624 0.0184 0.0183
Loa Loa (eye worm) CAMK/PIM protein kinase 0.3632 0.2959 0.3116
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Giardia lamblia Kinase, STE STE20 0.0581 0.0145 0.0686
Loa Loa (eye worm) hypothetical protein 0.0622 0.0182 0.0192
Leishmania major casein kinase, putative 0.1098 0.0621 0.2831
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1551 0.1039 0.1038
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.1273 0.0783 0.2266
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.2251 0.1684 0.7966
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1869 0.1332 0.1331
Giardia lamblia Kinase, PLK 0.1551 0.1039 0.6098
Brugia malayi phosphoinositide-dependent protein kinase I 0.0565 0.0129 0.0136
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0769 0.0318 0.1505
Brugia malayi protein-tyrosine kinase 0.1564 0.1051 0.1107
Echinococcus multilocularis protein kinase 0.0458 0.0031 0.003
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1199 0.0714 0.4129
Plasmodium falciparum calcium-dependent protein kinase 4 0.1012 0.0542 0.3091
Leishmania major protein kinase, putative 0.2251 0.1684 0.7935
Echinococcus multilocularis hemicentin 1 0.053 0.0098 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.074 0.0291 0.173
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.191 0.137 0.1443
Trypanosoma cruzi cdc2-related kinase 3 0.1112 0.0634 0.3
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.2141 0.1583 0.1667
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1336 0.0841 0.084
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.1012 0.0542 0.3091
Schistosoma mansoni hypothetical protein 0.0458 0.0031 0.0091
Entamoeba histolytica casein kinase, putative 0.1098 0.0621 0.2831
Onchocerca volvulus 0.0608 0.0169 0.0169
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 1.0721 0.9496 1
Loa Loa (eye worm) hypothetical protein 0.1675 0.1153 0.1214
Entamoeba histolytica cell division protein kinase 2, putative 0.1185 0.0701 0.3216
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0509 0.0078 0.0086
Echinococcus granulosus dual specificity 0.0809 0.0355 0.0395
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0458 0.0031 0.0033
Schistosoma mansoni adapter molecule crk 0.071 0.0263 0.0762
Echinococcus multilocularis dual specificity 0.0809 0.0355 0.0353
Echinococcus multilocularis protein kinase 0.0458 0.0031 0.003
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1564 0.1051 0.1173
Brugia malayi intracellular kinase 0.1199 0.0714 0.0752
Echinococcus multilocularis expressed protein 0.0573 0.0137 0.0136
Echinococcus granulosus dual specificity 0.0809 0.0355 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.0627 0.0187 0.0541
Echinococcus multilocularis fibroblast growth factor receptor 4 0.2519 0.1931 0.193
Leishmania major protein kinase, putative 0.1012 0.0542 0.2453
Echinococcus multilocularis kinase suppressor of Ras 1 0.0458 0.0031 0.003
Trypanosoma brucei casein kinase I, isoform 2 0.1098 0.0621 0.2831
Trichomonas vaginalis CAMK family protein kinase 0.1012 0.0542 0.322
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.4172 0.3456 0.3639
Entamoeba histolytica protein kinase, putative 0.2717 0.2114 1
Loa Loa (eye worm) TKL/LRRK protein kinase 0.1041 0.0569 0.0599
Loa Loa (eye worm) TK/EPH protein kinase 0.0885 0.0424 0.0447
Brugia malayi Protein kinase domain containing protein 0.3645 0.297 0.3127
Echinococcus multilocularis cyclin dependent kinase 19 0.208 0.1527 0.1526
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0662 0.0219 0.0231
Trypanosoma cruzi cdc2-related kinase 3 0.1112 0.0634 0.3
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.1198 0.0713 0.0712
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Echinococcus granulosus mitogen activated protein kinase 3 0.0576 0.014 0.0155
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.1213 0.0728 0.0811
Schistosoma mansoni tyrosine kinase 0.2519 0.1931 0.5589
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0809 0.0355 0.1552
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0717 0.027 0.03
Entamoeba histolytica casein kinase 1, putative 0.1098 0.0621 0.2831
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.1273 0.0783 0.0782
Entamoeba histolytica protein kinase, putative 0.0573 0.0137 0.0508
Schistosoma mansoni Neurotrimin precursor (hNT) 0.117 0.0687 0.1989
Brugia malayi Protein kinase domain containing protein 0.0565 0.0129 0.0136
Echinococcus granulosus protein kinase 0.1496 0.0988 0.1103
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0624 0.0184 0.0194
Brugia malayi Immunoglobulin I-set domain containing protein 0.0624 0.0184 0.0194
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.1012 0.0542 0.3091
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1916 0.1375 0.6452
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1012 0.0542 0.0571
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Entamoeba histolytica protein kinase, putative 0.186 0.1324 0.6204
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.1112 0.0634 0.0668
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0458 0.0031 0.003
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus titin 0.0721 0.0274 0.0304
Loa Loa (eye worm) hypothetical protein 0.053 0.0098 0.0103
Brugia malayi Protein kinase domain containing protein 0.1136 0.0656 0.0691
Schistosoma mansoni serine/threonine protein kinase 0.0846 0.0389 0.1125
Brugia malayi Protein kinase domain containing protein 0.0864 0.0405 0.0427
Schistosoma mansoni protein kinase 0.0717 0.027 0.0781
Brugia malayi casein kinase I 0.1098 0.0621 0.0654
Brugia malayi C-terminal src kinase protein 1 0.0458 0.0031 0.0033
Echinococcus granulosus aurora kinase A 0.1644 0.1125 0.1255
Onchocerca volvulus 0.16 0.1084 0.1174
Entamoeba histolytica protein kinase, putative 0.0717 0.027 0.1145
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Onchocerca volvulus 0.1098 0.0621 0.0665
Echinococcus granulosus tyrosine protein kinase Lyn 0.218 0.1619 0.1807
Schistosoma mansoni nephrin 0.158 0.1066 0.3083
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.208 0.1527 0.1608
Echinococcus granulosus mitogen activated protein kinase 14 0.213 0.1573 0.1756
Schistosoma mansoni protein kinase 0.0932 0.0468 0.1354
Giardia lamblia Kinase, CMGC DYRK 0.0809 0.0355 0.1956
Leishmania major protein kinase, putative 0.1644 0.1125 0.5248
Schistosoma mansoni serine/threonine protein kinase 0.2522 0.1934 0.5598
Brugia malayi hypothetical protein 0.1025 0.0554 0.0583
Echinococcus multilocularis casein kinase I alpha 0.1098 0.0621 0.062
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0458 0.0031 0.0033
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.2339 0.1766 0.1765
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.3408 0.2752 0.3073
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.1472 0.0966 0.4487
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Schistosoma mansoni serine/threonine protein kinase 0.2383 0.1806 0.5227
Trichomonas vaginalis STE family protein kinase 0.1916 0.1375 0.8166
Brugia malayi Protein kinase domain containing protein 0.7594 0.6612 0.6963
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.2251 0.1684 0.7966
Loa Loa (eye worm) hypothetical protein 0.16 0.1084 0.1142
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.1472 0.0966 0.4568
Loa Loa (eye worm) AUR protein kinase 0.1644 0.1125 0.1184
Echinococcus multilocularis casein kinase I delta 0.1098 0.0621 0.062
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.1025 0.0554 0.1603
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 1.0131 0.8952 1
Schistosoma mansoni protein kinase C mu 0.1911 0.1371 0.3967
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.1496 0.0988 0.1041
Loa Loa (eye worm) SRC-1 0.1869 0.1332 0.1403
Schistosoma mansoni cell adhesion molecule 0.0624 0.0184 0.0534
Echinococcus multilocularis casein kinase I delta 0.1098 0.0621 0.062
Echinococcus granulosus CDC7 cell division cycle 7 0.0608 0.0169 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Echinococcus multilocularis receptor type guanylyl cyclase 0.0458 0.0031 0.003
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0957 0.0492 0.049
Loa Loa (eye worm) AGC/PKN protein kinase 0.1891 0.1352 0.1424
Schistosoma mansoni serine/threonine protein kinase 0.1472 0.0966 0.2795
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.1481 0.0975 0.1026
Schistosoma mansoni tyrosine kinase 0.1254 0.0765 0.2213
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.3632 0.2959 0.3304
Echinococcus multilocularis N chimaerin 0.0756 0.0306 0.0305
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0671 0.0227 0.0239
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0996 0.0528 0.0588
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2565 0.1974 0.2204
Schistosoma mansoni septate junction protein 0.053 0.0098 0.0283
Brugia malayi Immunoglobulin I-set domain containing protein 0.0702 0.0256 0.0269
Loa Loa (eye worm) hypothetical protein 0.0795 0.0342 0.036
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.175 0.1223 0.1287
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Schistosoma mansoni serine/threonine protein kinase 0.2632 0.2036 0.5891
Entamoeba histolytica protein kinase, putative 0.1935 0.1393 0.6535
Trichomonas vaginalis CAMK family protein kinase 0.1275 0.0785 0.4659
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0064 0.0063
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.213 0.1573 0.7438
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0458 0.0031 0.0033
Echinococcus granulosus calcium activated potassium channel 0.0846 0.0389 0.0433
Trichomonas vaginalis CAMK family protein kinase 0.0799 0.0346 0.2053
Trichomonas vaginalis STE family protein kinase 0.0717 0.027 0.1603
Echinococcus granulosus tyrosine protein kinase 0.1711 0.1187 0.1325
Brugia malayi Furin-like cysteine rich region family protein 0.3895 0.32 0.337
Echinococcus granulosus twitchin 0.1797 0.1266 0.1413
Brugia malayi Peroxidasin 0.0535 0.0102 0.0108
Echinococcus multilocularis tyrosine protein kinase Srms 0.1564 0.1051 0.105
Echinococcus multilocularis growth factor receptor bound protein 2 0.071 0.0263 0.0262
Giardia lamblia Kinase, CMGC CDK 0.1112 0.0634 0.3647
Schistosoma mansoni serine/threonine protein kinase 0.0842 0.0385 0.1115
Schistosoma mansoni serine/threonine protein kinase 0.0565 0.0129 0.0374
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0576 0.014 0.0659
Loa Loa (eye worm) hypothetical protein 0.1012 0.0542 0.0571
Loa Loa (eye worm) hypothetical protein 0.0441 0.0015 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0958 0.0492 0.2921
Echinococcus granulosus tyrosine protein kinase Src64B 0.1869 0.1332 0.1487
Brugia malayi Protein kinase domain containing protein 0.0462 0.0035 0.0037
Echinococcus granulosus protein kinase shaggy 0.1199 0.0714 0.0796
Brugia malayi Receptor family ligand binding region containing protein 0.0458 0.0031 0.0033
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0565 0.0129 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.1273 0.0783 0.2266
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.1112 0.0634 0.0668
Trichomonas vaginalis AGC family protein kinase 0.0565 0.0129 0.0768
Schistosoma mansoni roundabout 0.053 0.0098 0.0283
Brugia malayi Variant SH3 domain containing protein 0.0487 0.0058 0.0061
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Schistosoma mansoni protein kinase 0.3773 0.3089 0.8938
Loa Loa (eye worm) TK/INSR protein kinase 0.3634 0.296 0.3117
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.2717 0.2114 1
Echinococcus multilocularis nervana 2 0.0646 0.0205 0.0203
Loa Loa (eye worm) hypothetical protein 0.0825 0.0369 0.0389
Echinococcus granulosus cyclin dependent kinase 7 0.1018 0.0548 0.0611
Trichomonas vaginalis CMGC family protein kinase 0.0576 0.014 0.0832
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0525 0.0093 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.1551 0.1039 0.3008
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0839 0.0383 0.1686
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.175 0.1223 0.1364
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) TK protein kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1129 0.065 0.0649
Echinococcus multilocularis 0.1049 0.0576 0.0575
Echinococcus multilocularis FL cytokine receptor 0.0458 0.0031 0.003
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2565 0.1974 0.1973
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Giardia lamblia Kinase, NEK 0.0958 0.0492 0.2787
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0726 0.0278 0.0293
Loa Loa (eye worm) hypothetical protein 0.1264 0.0774 0.0815
Trypanosoma brucei aurora B kinase 0.1644 0.1125 0.5248
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1551 0.1039 0.116
Schistosoma mansoni serine/threonine protein kinase 0.0846 0.0389 0.1125
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0458 0.0031 0.0033
Onchocerca volvulus 0.1199 0.0714 0.0767
Echinococcus granulosus roundabout 2 0.1794 0.1263 0.141
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.1254 0.0765 0.0805
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0489 0.0059 0.0065
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0573 0.0137 0.0508
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1025 0.0554 0.262
Loa Loa (eye worm) TK/ACK protein kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis roundabout 2 0.0624 0.0184 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Entamoeba histolytica protein kinase , putative 0.1644 0.1125 0.5248
Entamoeba histolytica protein kinase, putative 0.1199 0.0714 0.3277
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0458 0.0031 0.003
Schistosoma mansoni hypothetical protein 0.0535 0.0102 0.0295
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Trypanosoma cruzi casein kinase, delta isoform, putative 0.1098 0.0621 0.2937
Onchocerca volvulus Serine\/threonine kinase homolog 0.1551 0.1039 0.1124
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Echinococcus granulosus casein kinase i 0.1098 0.0621 0.0692
Entamoeba histolytica protein kinase, putative 0.0463 0.0036 0.0022
Echinococcus granulosus serine:threonine protein kinase N2 0.1891 0.1352 0.151
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0839 0.0383 0.181
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0458 0.0031 0.0034
Trypanosoma brucei Casein kinase II 0.0662 0.0219 0.0902
Trypanosoma cruzi casein kinase, putative 0.1098 0.0621 0.2937
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.1078
Entamoeba histolytica protein kinase, putative 0.0509 0.0078 0.0224
Trypanosoma cruzi polo-like protein kinase, putative 0.1551 0.1039 0.4915
Brugia malayi Protein kinase domain containing protein 0.1711 0.1187 0.125
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1869 0.1332 0.1331
Trypanosoma cruzi casein kinase, putative 0.1098 0.0621 0.2937
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi ribosomal protein S6 kinase alpha 3 0.162 0.1102 0.1161
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0576 0.014 0.0523
Plasmodium falciparum NIMA related kinase 1 0.0958 0.0492 0.2787
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Schistosoma mansoni tyrosine kinase 0.0989 0.052 0.1506
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0471 0.0043 0.0045
Loa Loa (eye worm) TK/DDR protein kinase 0.0458 0.0031 0.0033
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0576 0.014 0.0663
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0957 0.0492 0.0548
Giardia lamblia Kinase, CMGC SRPK 0.0573 0.0137 0.064
Trypanosoma cruzi cdc2-related kinase 1 0.1112 0.0634 0.3
Trichomonas vaginalis CK1 family protein kinase 0.1098 0.0621 0.3687
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0458 0.0031 0.0033
Plasmodium falciparum calcium-dependent protein kinase 5 0.1012 0.0542 0.3091
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.0098 0.0103
Entamoeba histolytica protein kinase, putative 0.1644 0.1125 0.5248
Onchocerca volvulus 0.0458 0.0031 0.0018
Brugia malayi Temporarily assigned gene name protein 59 0.0674 0.023 0.0243
Loa Loa (eye worm) CMGC/CLK protein kinase 0.2251 0.1684 0.1774
Loa Loa (eye worm) hypothetical protein 0.2066 0.1514 0.1594
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Echinococcus granulosus retinal guanylyl cyclase 2 0.0458 0.0031 0.0034
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Schistosoma mansoni titin 0.0721 0.0274 0.0792
Trypanosoma brucei polo-like protein kinase 0.1551 0.1039 0.4839
Schistosoma mansoni serine/threonine protein kinase 0.1363 0.0866 0.2505
Brugia malayi Tyrosine-protein kinase abl-1 0.1576 0.1062 0.1119
Trichomonas vaginalis AGC family protein kinase 0.1286 0.0795 0.4718
Echinococcus granulosus peroxidasin 0.0535 0.0102 0.0113
Echinococcus multilocularis hypothetical protein 0.0535 0.0102 0.0101
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1025 0.0554 0.2509
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.1112 0.0634 0.0707
Echinococcus granulosus tyrosine kinase 0.1564 0.1051 0.1173
Echinococcus granulosus casein kinase I alpha 0.1098 0.0621 0.0692
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.3658 0.2982 0.2981
Echinococcus granulosus serine:threonine kinase SAD 1 0.0839 0.0383 0.0426
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi protein kinase C3,putative 0.1095 0.0619 0.0651
Onchocerca volvulus 0.0458 0.0031 0.0018
Brugia malayi Protein kinase domain containing protein 0.0864 0.0405 0.0427
Echinococcus multilocularis mitogen activated protein kinase 3 0.0576 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.1012 0.0542 0.0604
Loa Loa (eye worm) hypothetical protein 0.053 0.0098 0.0103
Echinococcus multilocularis tyrosine protein kinase shark 0.198 0.1434 0.1433
Schistosoma mansoni serine/threonine protein kinase 0.0839 0.0383 0.1107
Giardia lamblia Kinase, CAMK CAMKL 0.0912 0.045 0.2531
Loa Loa (eye worm) hypothetical protein 0.1434 0.0931 0.0981
Echinococcus granulosus tyrosine protein kinase Src42A 0.1869 0.1332 0.1487
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0562 0.0127 0.0579
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0756 0.0306 0.0885
Schistosoma mansoni rap gtpase-activating protein 0.1025 0.0554 0.1603
Giardia lamblia Kinase, NEK 0.0958 0.0492 0.2787
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0509 0.0078 0.0077
Brugia malayi Protein kinase domain containing protein 0.2524 0.1936 0.2039
Schistosoma mansoni protein kinase 0.0662 0.0219 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Schistosoma mansoni serine/threonine protein kinase 0.1112 0.0634 0.1835
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0573 0.0137 0.0649
Echinococcus granulosus Protein kinase C brain isozyme 0.1778 0.1248 0.1393
Brugia malayi Protein kinase domain containing protein 0.3632 0.2959 0.3116
Schistosoma mansoni serine/threonine protein kinase 0.0608 0.0169 0.049
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0839 0.0383 0.1686
Schistosoma mansoni cell adhesion molecule 0.0624 0.0184 0.0534
Trichomonas vaginalis AGC family protein kinase 0.1472 0.0966 0.5735
Onchocerca volvulus 0.1675 0.1153 0.1249
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1869 0.1332 0.1487
Echinococcus granulosus NDR protein kinase 0.1213 0.0728 0.0811
Onchocerca volvulus 0.0458 0.0031 0.0018
Brugia malayi Protein kinase domain containing protein 0.1253 0.0764 0.0805
Plasmodium falciparum serine/threonine protein kinase, putative 0.1644 0.1125 0.6614
Entamoeba histolytica protein kinase 2, putative 0.0957 0.0492 0.2209
Onchocerca volvulus 0.0458 0.0031 0.0018
Echinococcus granulosus dual specificity mitogen activated protein 0.1916 0.1375 0.1535
Onchocerca volvulus 0.0458 0.0031 0.0018
Loa Loa (eye worm) AUR protein kinase 0.1644 0.1125 0.1184
Loa Loa (eye worm) hypothetical protein 0.053 0.0098 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.0098 0.0103
Echinococcus multilocularis tyrosine protein kinase Abl 0.2144 0.1586 0.1585
Echinococcus multilocularis NCK adaptor protein 0.074 0.0291 0.029
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.1161 0.0679 0.0678
Echinococcus multilocularis mitogen activated protein kinase 14 0.213 0.1573 0.1572
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Brugia malayi Guanylyl cyclase protein 23 0.0458 0.0031 0.0033
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.1472 0.0966 0.4568
Brugia malayi Doublecortin family protein 0.0927 0.0464 0.0488
Schistosoma mansoni cell adhesion molecule 0.1478 0.0972 0.2812
Brugia malayi Protein kinase domain containing protein 0.1147 0.0666 0.0701
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.2339 0.1766 0.1971
Loa Loa (eye worm) serine/threonine protein kinase 0.0458 0.0031 0.0033
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0581 0.0145 0.0544
Trypanosoma cruzi casein kinase, putative 0.1098 0.0621 0.2937
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.1112 0.0634 0.2894
Trichomonas vaginalis CAMK family protein kinase 0.1551 0.1039 0.6171
Schistosoma mansoni tyrosine kinase 0.3383 0.2729 0.7897
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.1012 0.0542 0.0571
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.1112 0.0634 0.0668
Onchocerca volvulus 0.0535 0.0102 0.0095
Brugia malayi Protein kinase domain containing protein 0.1798 0.1267 0.1334
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0717 0.027 0.03
Loa Loa (eye worm) hypothetical protein 0.6692 0.578 0.6087
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.1042 0.057 0.0635
Brugia malayi SH2 domain containing protein 0.0864 0.0405 0.0427
Loa Loa (eye worm) hypothetical protein 0.0795 0.0342 0.036
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0458 0.0031 0.0091
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0458 0.0031 0.003
Entamoeba histolytica protein kinase, putative 0.0679 0.0235 0.0976
Loa Loa (eye worm) AUR protein kinase 0.1644 0.1125 0.1184
Echinococcus granulosus epidermal growth factor receptor 0.3895 0.32 0.3574
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Trichomonas vaginalis CMGC family protein kinase 0.0576 0.014 0.0832
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1199 0.0714 0.0713
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0458 0.0031 0.0033
Schistosoma mansoni protein kinase 0.1426 0.0923 0.2672
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.2251 0.1684 0.7935
Trypanosoma brucei protein kinase, putative 0.1199 0.0714 0.3277
Leishmania major protein kinase A catalytic subunit isoform 2 0.1472 0.0966 0.4487
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Entamoeba histolytica protein kinase, putative 0.0565 0.0129 0.047
Echinococcus multilocularis ephrin type A receptor 4 A 0.0793 0.034 0.0339
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0458 0.0031 0.003
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.1012 0.0542 0.3091
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Echinococcus granulosus mitogen activated protein kinase 11 0.213 0.1573 0.1756
Brugia malayi MAP kinase sur-1 0.0576 0.014 0.0148
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0839 0.0383 0.0381
Trichomonas vaginalis CMGC family protein kinase 0.0809 0.0355 0.2105
Schistosoma mansoni growth factor receptor-bound protein 0.074 0.0291 0.0843
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi Immunoglobulin I-set domain containing protein 0.2835 0.2223 0.2341
Echinococcus granulosus serine:threonine protein kinase TAO1 0.3255 0.2611 0.2915
Trypanosoma cruzi casein kinase, putative 0.1098 0.0621 0.2937
Echinococcus granulosus growth factor receptor bound protein 2 0.074 0.0291 0.0324
Loa Loa (eye worm) hypothetical protein 0.0839 0.0383 0.0403
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus multilocularis beta adrenergic receptor kinase 0.0471 0.0043 0.0042
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.1472 0.0966 0.1017
Trypanosoma brucei protein kinase, putative 0.0769 0.0318 0.1377
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Echinococcus granulosus protein tyrosine kinase 0.3607 0.2935 0.3278
Echinococcus granulosus tyrosine protein kinase Srms 0.2995 0.237 0.2647
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.1644 0.1125 0.5248
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.0043 0.0124
Echinococcus granulosus hypothetical protein 0.194 0.1397 0.156
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.1384 0.0885 0.0987
Entamoeba histolytica protein kinase domain containing protein 0.0726 0.0278 0.1183
Echinococcus granulosus natriuretic peptide receptor 1 0.0458 0.0031 0.0034
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0716 0.0269 0.1142
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.1098 0.0621 0.0654
Echinococcus multilocularis CDC7 cell division cycle 7 0.0608 0.0169 0.0168
Giardia lamblia Kinase, CMGC MAPK 0.0576 0.014 0.0659
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.0098 0.0103
Trypanosoma brucei rac serine-threonine kinase, putative 0.1935 0.1393 0.6535
Schistosoma mansoni serine/threonine protein kinase 0.1778 0.1248 0.3612
Trypanosoma cruzi casein kinase II, putative 0.0662 0.0219 0.1036
Giardia lamblia Kinase, CAMK CAMKL 0.0912 0.045 0.2531
Echinococcus granulosus plexin a4 0.0438 0.0013 0.0013
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0581 0.0145 0.0684
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0624 0.0184 0.0205
Echinococcus granulosus casein kinase I alpha 0.1098 0.0621 0.0692
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.3632 0.2959 0.2958
Echinococcus multilocularis integrin linked protein kinase 0.0458 0.0031 0.003
Echinococcus multilocularis mitogen activated protein kinase 0.0576 0.014 0.0139
Echinococcus granulosus tyrosine protein kinase shark 0.198 0.1434 0.1601
Echinococcus multilocularis casein kinase ii subunit alpha 0.0662 0.0219 0.0218
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.2761 0.2155 0.2269
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.213 0.1573 0.1656
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0769 0.0318 0.1736
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.3773 0.3089 0.3088
Echinococcus granulosus casein kinase ii subunit alpha 0.0662 0.0219 0.0243
Echinococcus granulosus serine:threonine protein kinase 12 B 0.1644 0.1125 0.1255
Echinococcus multilocularis neuroglian 0.0624 0.0184 0.0183
Loa Loa (eye worm) hypothetical protein 0.1253 0.0764 0.0805
Plasmodium falciparum serine/threonine protein kinase 0.0573 0.0137 0.064
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0458 0.0031 0.0091
Schistosoma mansoni tyrosine kinase 0.1869 0.1332 0.3855
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.1161 0.0679 0.0757
Loa Loa (eye worm) thyroid receptor interactor 0.0688 0.0243 0.0256
Echinococcus granulosus roundabout 2 0.0624 0.0184 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0576 0.014 0.0832
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Plasmodium falciparum calcium-dependent protein kinase 3 0.1012 0.0542 0.3091
Echinococcus multilocularis dual specificity mitogen activated protein 0.1916 0.1375 0.1374
Schistosoma mansoni serine/threonine protein kinase 0.2717 0.2114 0.6119
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Schistosoma mansoni serine/threonine protein kinase 0.0842 0.0385 0.1115
Echinococcus granulosus hemicentin 1 0.053 0.0098 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.1551 0.1039 0.6171
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Echinococcus granulosus raf serine:threonine protein kinase 0.0809 0.0355 0.0395
Loa Loa (eye worm) CDC7 protein kinase 0.0608 0.0169 0.0178
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0581 0.0145 0.0684
Leishmania major casein kinase II, putative 0.0662 0.0219 0.0902
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0721 0.0274 0.0288
Trypanosoma cruzi protein kinase, putative 0.0458 0.0031 0.0148
Brugia malayi hypothetical protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0927 0.0464 0.0488
Loa Loa (eye worm) hypothetical protein 0.0528 0.0096 0.0101
Schistosoma mansoni tyrosine kinase 0.198 0.1434 0.415
Schistosoma mansoni serine/threonine protein kinase 0.1472 0.0966 0.2795
Loa Loa (eye worm) TK protein kinase 0.1711 0.1187 0.125
Echinococcus multilocularis mitogen activated protein kinase 14 0.213 0.1573 0.1572
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0458 0.0031 0.0018
Entamoeba histolytica hypothetical protein 0.0463 0.0036 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi Casein kinase II, alpha chain 0.0662 0.0219 0.0231
Loa Loa (eye worm) hypothetical protein 0.053 0.0098 0.0103
Schistosoma mansoni nephrin 0.0624 0.0184 0.0534
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.1571 0.1057 0.1113
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1199 0.0714 0.2066
Schistosoma mansoni tyrosine kinase 0.2348 0.1774 0.5134
Plasmodium vivax serine/threonine protein kinase, putative 0.0573 0.0137 0.064
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.175 0.1223 0.1287
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Giardia lamblia Kinase, CDC7 0.0608 0.0169 0.0835
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus tyrosine protein kinase ABL1 0.3416 0.2759 0.3081
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Plasmodium vivax protein kinase Crk2 0.1112 0.0634 0.3647
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.1136 0.0656 0.0691
Trichomonas vaginalis STE family protein kinase 0.1916 0.1375 0.8166
Loa Loa (eye worm) hypothetical protein 0.117 0.0687 0.0724
Schistosoma mansoni tyrosine kinase 0.3895 0.32 0.9261
Schistosoma mansoni tyrosine kinase 0.1869 0.1332 0.3855
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis serine:threonine protein kinase N2 0.0678 0.0234 0.0232
Echinococcus granulosus cGMP dependent protein kinase 1 0.0842 0.0385 0.0429
Trypanosoma brucei protein kinase, putative 0.0649 0.0207 0.0845
Giardia lamblia Kinase, CK1 Casein kinase 0.1098 0.0621 0.3567
Entamoeba histolytica tyrosin kinase, putative 0.0551 0.0116 0.0408
Schistosoma mansoni serine/threonine-protein kinase 0.1032 0.0561 0.1622
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.213 0.1573 0.74
Loa Loa (eye worm) TK protein kinase 0.1564 0.1051 0.1107
Trichomonas vaginalis CMGC family protein kinase 0.1112 0.0634 0.3766
Echinococcus granulosus cyclin dependent kinase 1 0.1112 0.0634 0.0707
Brugia malayi Immunoglobulin I-set domain containing protein 0.0624 0.0184 0.0194
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0624 0.0184 0.0183
Entamoeba histolytica protein kinase, putative 0.2717 0.2114 1
Loa Loa (eye worm) hypothetical protein 0.1264 0.0774 0.0815
Onchocerca volvulus 0.0608 0.0169 0.0169
Brugia malayi Fibronectin type III domain containing protein 0.1264 0.0774 0.0815
Brugia malayi Variant SH3 domain containing protein 0.071 0.0263 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.1644 0.1125 0.3254
Entamoeba histolytica protein kinase, putative 0.1019 0.0548 0.2482
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) TK protein kinase 0.0458 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.134 0.0844 0.0889
Schistosoma mansoni serine/threonine protein kinase 0.208 0.1527 0.4419
Echinococcus granulosus calcium dependent protein kinase 0.0701 0.0255 0.0284
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.194 0.1398 0.1397
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0458 0.0031 0.0091
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0839 0.0383 0.181
Schistosoma mansoni tyrosine kinase 0.3011 0.2385 0.6902
Schistosoma mansoni serine/threonine protein kinase 0.2199 0.1637 0.4736
Echinococcus granulosus contactin 0.0624 0.0184 0.0205
Loa Loa (eye worm) TK/CSK protein kinase 0.0458 0.0031 0.0033
Schistosoma mansoni vam6/vps39 related 0.1025 0.0554 0.1603
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.1112 0.0634 0.3647
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.1025 0.0554 0.262
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.1644 0.1125 0.1124
Brugia malayi Protein kinase domain containing protein 0.3275 0.2629 0.2768
Echinococcus multilocularis lachesin 0.053 0.0098 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.191 0.137 0.3964
Brugia malayi serine/threonine kinase 12 0.1644 0.1125 0.1184
Echinococcus granulosus tyrosine protein kinase csk 0.0458 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.2351 0.1777 0.1872
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.1198 0.0713 0.0751
Loa Loa (eye worm) TK/Met protein kinase 0.0458 0.0031 0.0033
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.1012 0.0542 0.0571
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Echinococcus multilocularis casein kinase I alpha 0.1098 0.0621 0.062
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Onchocerca volvulus 0.0864 0.0405 0.0428
Loa Loa (eye worm) RGC/RGC protein kinase 0.0458 0.0031 0.0033
Onchocerca volvulus 0.0864 0.0405 0.0428
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.0098 0.0103
Echinococcus multilocularis basement membrane specific heparan sulfate 0.117 0.0687 0.0686
Echinococcus granulosus receptor type guanylyl cyclase 0.0458 0.0031 0.0034
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.1025 0.0554 0.1603
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0573 0.0137 0.0508
Brugia malayi serine/threonine-protein kinase PAK 7 0.2858 0.2244 0.2363
Echinococcus multilocularis Glutaredoxin protein 5 0.0646 0.0205 0.0203
Echinococcus multilocularis tyrosine protein kinase 0.1711 0.1187 0.1186
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.3657 0.2981 0.8627
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.0965
Echinococcus multilocularis heat shock protein 70 0.0458 0.0031 0.003
Brugia malayi Protein kinase domain containing protein 0.1275 0.0785 0.0826
Brugia malayi Immunoglobulin I-set domain containing protein 0.7079 0.6137 0.6463
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0031 0.0091
Echinococcus granulosus Immunoglobulin 0.117 0.0687 0.0767
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.2723 0.2119 0.2119
Brugia malayi Tyrosine-protein kinase abl-1 0.2144 0.1586 0.167
Echinococcus multilocularis tyrosine protein kinase ABL1 0.3416 0.2759 0.2758
Brugia malayi Serine/threonine-protein kinase Pim-3 0.3632 0.2959 0.3116
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2858 0.2244 0.2363
Schistosoma mansoni serine/threonine protein kinase 0.0573 0.0137 0.0397
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis 0.194 0.1397 0.1396
Brugia malayi hypothetical protein 0.0458 0.0031 0.0033
Giardia lamblia Kinase, STE STE20 0.0717 0.027 0.1444
Echinococcus granulosus N chimaerin 0.0756 0.0306 0.034
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.2251 0.1684 0.4874
Schistosoma mansoni protein kinase 0.3408 0.2752 0.7963
Loa Loa (eye worm) hypothetical protein 0.1175 0.0692 0.0729
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni kinase 0.0726 0.0278 0.0804
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi Protein kinase domain containing protein 0.1935 0.1393 0.1467
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni tyrosine kinase 0.2348 0.1774 0.5134
Echinococcus granulosus tyrosine protein kinase Fyn 0.1869 0.1332 0.1487
Echinococcus granulosus neuroglian 0.0624 0.0184 0.0205
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0458 0.0031 0.0034
Trichomonas vaginalis AGC family protein kinase 0.1644 0.1125 0.6677
Echinococcus granulosus cyclin dependent kinase 9 0.0798 0.0345 0.0384
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0458 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.053 0.0098 0.0103
Trichomonas vaginalis AGC family protein kinase 0.1644 0.1125 0.6677
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.053 0.0098 0.0103
Onchocerca volvulus 0.5236 0.4438 0.4855
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0839 0.0383 0.1686
Schistosoma mansoni protein kinase 0.2521 0.1934 0.5596
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Loa Loa (eye worm) hypothetical protein 0.0671 0.0227 0.0239
Trichomonas vaginalis protein tyrosine kinase, putative 0.0458 0.0031 0.0186
Brugia malayi hypothetical protein 0.1264 0.0774 0.0815
Loa Loa (eye worm) TK/EGFR protein kinase 0.3895 0.32 0.337
Echinococcus granulosus tyrosine protein kinase Fyn 0.1869 0.1332 0.1487
Brugia malayi putative serine/threonine kinase SADA gamma 0.0839 0.0383 0.0403
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.1275 0.0785 0.0826
Entamoeba histolytica protein kinase, putative 0.1159 0.0677 0.3101
Echinococcus granulosus dual specificity protein kinase clk2 0.2251 0.1684 0.188
Schistosoma mansoni serine/threonine protein kinase 0.0839 0.0383 0.1107
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.1213 0.0728 0.0811
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.186 0.1324 0.1394
Echinococcus multilocularis tyrosine protein kinase csk 0.0458 0.0031 0.003
Schistosoma mansoni serine/threonine protein kinase 0.1112 0.0634 0.1835
Echinococcus multilocularis rho associated protein kinase 0.3657 0.2981 0.298
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis protein KINase family member (kin 25) 0.1254 0.0765 0.0764
Trichomonas vaginalis CMGC family protein kinase 0.1199 0.0714 0.4239
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0428 0.0003 0.0018
Echinococcus multilocularis cyclin dependent kinase 9 0.0798 0.0345 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.0839 0.0383 0.1107
Echinococcus granulosus beta-adrenergic receptor kinase 0.0471 0.0043 0.0047
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0646 0.0205 0.0227
Giardia lamblia Kinase, CMGC CLK 0.2251 0.1684 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0458 0.0031 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0809 0.0355 0.2105
Schistosoma mansoni nck2/grb4 0.071 0.0263 0.0762
Echinococcus multilocularis tyrosine kinase 0.0458 0.0031 0.003
Onchocerca volvulus 0.1249 0.0761 0.0818
Brugia malayi ephrin receptor 1 precursor 0.0616 0.0177 0.0186
Schistosoma mansoni protein kinase 0.3773 0.3089 0.8938
Giardia lamblia Kinase, AGC PKA 0.0957 0.0492 0.2784
Echinococcus granulosus titin 0.0721 0.0274 0.0304
Echinococcus granulosus MAM 0.0441 0.0015 0.0015
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.191 0.137 0.1443
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0624 0.0184 0.0183
Loa Loa (eye worm) AGC/PKA protein kinase 0.1472 0.0966 0.1017
Echinococcus granulosus epidermal growth factor receptor 0.2807 0.2197 0.2453
Echinococcus multilocularis natriuretic peptide receptor 1 0.0458 0.0031 0.003
Brugia malayi Protein kinase domain containing protein 0.0573 0.0137 0.0144
Brugia malayi Variant SH3 domain containing protein 0.0756 0.0306 0.0322
Loa Loa (eye worm) hypothetical protein 0.3275 0.2629 0.2768
Brugia malayi Protein kinase c protein 2 0.0876 0.0416 0.0438
Echinococcus granulosus insulin growth factor 1 receptor beta 0.3728 0.3047 0.3403
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Schistosoma mansoni tyrosine protein kinase 0.0458 0.0031 0.0091
Entamoeba histolytica serine/threonine protein kinase, putative 0.0839 0.0383 0.1686
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Trichomonas vaginalis AGC family protein kinase 0.1255 0.0766 0.4548
Entamoeba histolytica protein kinase domain containing protein 0.0809 0.0355 0.1552
Echinococcus granulosus serine/threonine protein kinase 0.1032 0.0561 0.0625
Loa Loa (eye worm) hypothetical protein 0.1472 0.0966 0.1017
Schistosoma mansoni hypothetical protein 0.0441 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.0441 0.0015 0.0016
Echinococcus multilocularis casein kinase I alpha 0.1098 0.0621 0.062
Echinococcus granulosus tyrosine kinase 0.0864 0.0405 0.0451
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0458 0.0031 0.003
Loa Loa (eye worm) CAMK/PIM protein kinase 0.3632 0.2959 0.3116
Trichomonas vaginalis CMGC family protein kinase 0.0809 0.0355 0.2105
Entamoeba histolytica PH domain containing protein kinase, putative 0.1032 0.0561 0.2541
Echinococcus granulosus tyrosine protein kinase Fyn 0.1869 0.1332 0.1487
Schistosoma mansoni ste20-related kinase 0.1211 0.0725 0.2099
Schistosoma mansoni serine/threonine protein kinase 0.1056 0.0582 0.1685
Echinococcus multilocularis casein kinase I gamma 0.1253 0.0764 0.0763
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0702 0.0256 0.0269
Entamoeba histolytica hypothetical protein 0.0463 0.0036 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.1571 0.1057 0.3059
Plasmodium falciparum casein kinase 2, alpha subunit 0.0662 0.0219 0.1136
Echinococcus multilocularis Immunoglobulin 0.117 0.0687 0.0686
Giardia lamblia Kinase, AGC PKA 0.1472 0.0966 0.5654
Echinococcus granulosus dual specificity 0.2717 0.2114 0.2361
Schistosoma mansoni tyrosine kinase 0.1168 0.0686 0.1986
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1869 0.1332 0.1487
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Onchocerca volvulus 0.2001 0.1454 0.1579
Echinococcus multilocularis c src tyrosine kinase 0.1168 0.0686 0.0685
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0458 0.0031 0.0033
Trichomonas vaginalis STE family protein kinase 0.0581 0.0145 0.0859
Echinococcus granulosus tyrosine protein kinase pr2 0.0458 0.0031 0.0034
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.071 0.0263 0.0762
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1199 0.0714 0.0752
Trichomonas vaginalis CMGC family protein kinase 0.0809 0.0355 0.2105
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Onchocerca volvulus 0.0618 0.0178 0.0179
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.1472 0.0966 0.4487
Echinococcus multilocularis dual specificity 0.2717 0.2114 0.2114
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.3275 0.2629 0.2768
Loa Loa (eye worm) hypothetical protein 0.1384 0.0885 0.0932
Brugia malayi bone morphogenetic protein type 1 receptor 0.1426 0.0923 0.0972
Entamoeba histolytica hypothetical protein 0.1986 0.144 0.6765
Schistosoma mansoni tyrosine kinase 0.3634 0.296 0.8566
Schistosoma mansoni tyrosine kinase 0.2348 0.1774 0.5134
Echinococcus multilocularis aurora kinase A 0.1644 0.1125 0.1124
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0458 0.0031 0.003
Echinococcus multilocularis protein kinase c iota type 0.1997 0.1451 0.145
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0573 0.0137 0.064
Leishmania major protein kinase A catalytic subunit 0.1472 0.0966 0.4487
Echinococcus granulosus nervana 2 0.0646 0.0205 0.0227
Onchocerca volvulus 0.0458 0.0031 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0576 0.014 0.0663
Brugia malayi P38 map kinase family protein 2 0.213 0.1573 0.1656
Echinococcus granulosus activin receptor type 0.5709 0.4873 0.5443
Echinococcus multilocularis peroxidasin 0.0535 0.0102 0.0101
Onchocerca volvulus 0.0864 0.0405 0.0428
Loa Loa (eye worm) hypothetical protein 0.3214 0.2573 0.2709
Echinococcus multilocularis tyrosine kinase 0.0864 0.0405 0.0404
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Schistosoma mansoni protein kinase 0.0604 0.0165 0.0479
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.2522 0.1934 0.216
Loa Loa (eye worm) hypothetical protein 0.0535 0.0102 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Loa Loa (eye worm) hypothetical protein 0.0458 0.0031 0.0033
Plasmodium vivax unspecified product 0.0662 0.0219 0.1136
Loa Loa (eye worm) TK protein kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0717 0.027 0.0269
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0463 0.0036 0.0022
Loa Loa (eye worm) hypothetical protein 0.0535 0.0102 0.0107
Echinococcus granulosus retinal guanylyl cyclase 2 0.0458 0.0031 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.1098 0.0621 0.1797
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.1472 0.0966 0.4487
Brugia malayi Cam kinase protein 1 0.1012 0.0542 0.0571
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0932 0.0468 0.0467
Trichomonas vaginalis protein kinase atn1, putative 0.0458 0.0031 0.0186
Loa Loa (eye worm) TK protein kinase 0.2835 0.2223 0.2341
Onchocerca volvulus 0.0787 0.0334 0.035
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.0965
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.194 0.1398 0.1561
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0717 0.027 0.03
Brugia malayi hypothetical protein 0.0864 0.0405 0.0427
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.1112 0.0634 0.2894
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0944 0.0479 0.2845
Loa Loa (eye worm) AGC/PKA protein kinase 0.1472 0.0966 0.1017
Echinococcus granulosus neuroglian 0.1486 0.0979 0.1092
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.1078
Toxoplasma gondii AGC kinase 0.1472 0.0966 0.5654
Brugia malayi serine/threonine-protein kinase 6 0.1644 0.1125 0.1184
Entamoeba histolytica p21-activated kinase 0.0792 0.0339 0.1477
Onchocerca volvulus 0.0458 0.0031 0.0018
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1012 0.0542 0.0604
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0562 0.0127 0.0579
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1869 0.1332 0.1331
Schistosoma mansoni serine/threonine protein kinase 0.2339 0.1766 0.5109
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0896 0.0435 0.0434
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.1078
Brugia malayi Pleckstrin Homology Domain 0.0426 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein kinase N2 0.1891 0.1352 0.1351
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.1025 0.0554 0.0618
Brugia malayi Protein kinase domain containing protein 0.0996 0.0528 0.0556
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0756 0.0306 0.034
Echinococcus multilocularis serine:threonine protein kinase 0.0738 0.029 0.0288
Brugia malayi Protein kinase domain containing protein 1.0721 0.9496 1
Onchocerca volvulus 0.0458 0.0031 0.0018
Entamoeba histolytica protein kinase, putative 0.0716 0.0269 0.1142
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0064 0.007
Loa Loa (eye worm) AGC/AKT protein kinase 0.1935 0.1393 0.1467
Schistosoma mansoni serine/threonine protein kinase 0.0721 0.0274 0.0792
Echinococcus granulosus protein kinase c epsilon type 0.1571 0.1057 0.118
Plasmodium vivax casein kinase 1, putative 0.1098 0.0621 0.3567
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Loa Loa (eye worm) variant SH3 domain-containing protein 0.071 0.0263 0.0277
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1916 0.1375 0.6452
Echinococcus granulosus NCK adaptor protein 0.071 0.0263 0.0293
Schistosoma mansoni cell adhesion molecule 0.053 0.0098 0.0283
Loa Loa (eye worm) RGC/RGC protein kinase 0.0458 0.0031 0.0033
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Schistosoma mansoni protein kinase 0.3773 0.3089 0.8938
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0996 0.0528 0.0556
Echinococcus granulosus casein kinase I delta 0.1098 0.0621 0.0692
Entamoeba histolytica protein kinase domain containing protein 0.1198 0.0713 0.3274
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis hemicentin 1 0.053 0.0098 0.0097
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.2251 0.1684 0.7935
Loa Loa (eye worm) hypothetical protein 0.1025 0.0554 0.0583
Entamoeba histolytica hypothetical protein 0.0463 0.0036 0.0022
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.3408 0.2752 0.2898
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0565 0.0129 0.0136
Echinococcus granulosus insulin receptor 0.3634 0.296 0.3306
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.2717 0.2114 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.1012 0.0542 0.3091
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.3275 0.2629 0.2768
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1869 0.1332 0.1331
Loa Loa (eye worm) TK/ROR protein kinase 0.0775 0.0323 0.034
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0957 0.0492 0.2325
Echinococcus multilocularis PAK box P21 Rho binding 0.0604 0.0165 0.0164
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0458 0.0031 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.1778 0.1248 0.3612
Entamoeba histolytica casein kinase, putative 0.0662 0.0219 0.0902
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0842 0.0385 0.2142
Toxoplasma gondii AGC kinase 0.186 0.1324 0.7818
Plasmodium falciparum protein kinase 5 0.1112 0.0634 0.3647
Entamoeba histolytica serine/threonine protein kinase, putative 0.1551 0.1039 0.4839
Brugia malayi serine/threonine protein kinase 6 0.1644 0.1125 0.1184
Brugia malayi Protein kinase domain containing protein 0.3275 0.2629 0.2768
Trypanosoma cruzi polo-like protein kinase, putative 0.1551 0.1039 0.4915
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Onchocerca volvulus 0.0721 0.0274 0.0284
Entamoeba histolytica cell division protein kinase 2, putative 0.1112 0.0634 0.2894
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.1472 0.0966 0.2795
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Echinococcus multilocularis activin receptor type 0.5709 0.4873 0.4873
Echinococcus granulosus tyrosine protein kinase Btk29A 0.3658 0.2982 0.333
Echinococcus multilocularis serine:threonine protein kinase N2 0.1213 0.0728 0.0726
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0637 0.0196 0.0207
Trichomonas vaginalis CMGC family protein kinase 0.0809 0.0355 0.2105
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.2717 0.2114 0.2227
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0958 0.0492 0.2787
Echinococcus granulosus Glutaredoxin protein 5 0.0646 0.0205 0.0227
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1869 0.1332 0.1331
Loa Loa (eye worm) hypothetical protein 0.2406 0.1828 0.1925
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.0512 0.0511
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.2519 0.1931 0.2156
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1426 0.0923 0.0972
Trichomonas vaginalis AGC family protein kinase 0.1935 0.1393 0.8269
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1916 0.1375 0.6505
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0458 0.0031 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0662 0.0219 0.0902
Echinococcus multilocularis dual specificity protein kinase clk2 0.2251 0.1684 0.1683
Echinococcus granulosus STE20 serine:threonine protein kinase 0.2723 0.2119 0.2367
Loa Loa (eye worm) TK/ALK protein kinase 0.7591 0.661 0.696
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.0965
Loa Loa (eye worm) hypothetical protein 0.1025 0.0554 0.0583
Giardia lamblia Kinase, CMGC CK2 0.0662 0.0219 0.1136
Trichomonas vaginalis CK1 family protein kinase 0.1098 0.0621 0.3687
Trichomonas vaginalis CMGC family protein kinase 0.2251 0.1684 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1911 0.1371 0.1444
Echinococcus granulosus tyrosine protein kinase Blk 0.1564 0.1051 0.1173
Schistosoma mansoni protein kinase 0.1916 0.1375 0.398
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Schistosoma mansoni tyrosine kinase 0.1574 0.106 0.3069
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus serine:threonine protein kinase 0.0738 0.029 0.0322
Echinococcus multilocularis cyclin dependent kinase 7 0.1018 0.0548 0.0547
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0809 0.0355 0.1552
Trypanosoma cruzi cdc2-related kinase 1 0.1112 0.0634 0.3
Echinococcus granulosus protein kinase C gamma type 0.1427 0.0925 0.1032
Echinococcus multilocularis rac serine:threonine kinase 0.1032 0.0561 0.056
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.3773 0.3089 0.3449
Echinococcus granulosus cyclin dependent kinase 0.1112 0.0634 0.0707
Echinococcus granulosus serine:threonine protein kinase MARK2 0.1273 0.0783 0.0873
Brugia malayi Protein kinase domain containing protein 0.1041 0.0569 0.0599
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.1098 0.0621 0.0654
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.3255 0.2611 0.2749
Loa Loa (eye worm) hypothetical protein 0.17 0.1176 0.1239
Trichomonas vaginalis CAMK family protein kinase 0.1551 0.1039 0.6171
Loa Loa (eye worm) RGC/RGC protein kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.3408 0.2752 0.2751
Loa Loa (eye worm) hypothetical protein 0.048 0.0051 0.0054
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1199 0.0714 0.0752
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0558 0.0123 0.013
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0509 0.0078 0.0086
Loa Loa (eye worm) casein kinase 0.0942 0.0477 0.0503
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.213 0.1573 0.7438
Echinococcus granulosus serine:threonine protein kinase 3 0.1481 0.0975 0.1087
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0624 0.0184 0.0183
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0787 0.0334 0.158
Brugia malayi C1-like domain containing protein 0.1911 0.1371 0.1444
Echinococcus multilocularis serine:threonine protein kinase 0.0738 0.029 0.0288
Echinococcus granulosus defective proboscis extension response 0.117 0.0687 0.0767
Schistosoma mansoni kinase 0.1648 0.1128 0.3265
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0576 0.014 0.0663
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis 0.1496 0.0988 0.0987
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1869 0.1332 0.1331
Schistosoma mansoni ephrin receptor 0.0552 0.0118 0.0342
Loa Loa (eye worm) RGC/RGC protein kinase 0.0458 0.0031 0.0033
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0717 0.027 0.0269
Echinococcus granulosus MAP kinase activated protein kinase 2 0.2199 0.1637 0.1827
Schistosoma mansoni serine/threonine protein kinase 0.1253 0.0764 0.2212
Loa Loa (eye worm) TK/FER protein kinase 0.1129 0.065 0.0684
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0717 0.027 0.0269
Loa Loa (eye worm) TK/FER protein kinase 0.0864 0.0405 0.0427
Echinococcus granulosus rho-associated protein kinase 1 0.3657 0.2981 0.3329
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0458 0.0031 0.0186
Echinococcus multilocularis Immunoglobulin 0.117 0.0687 0.0686
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1911 0.1371 0.1444
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.1213 0.0728 0.0726
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0738 0.029 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0809 0.0355 0.1026
Schistosoma mansoni protein kinase 0.0458 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.2524 0.1936 0.2039
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0458 0.0031 0.0033
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1199 0.0714 0.3277
Echinococcus granulosus serine:threonine protein kinase N2 0.0678 0.0234 0.026
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) hypothetical protein 0.0528 0.0096 0.0101
Loa Loa (eye worm) hypothetical protein 0.17 0.1176 0.1239
Echinococcus granulosus protein kinase 0.0458 0.0031 0.0034
Trypanosoma brucei cdc2-related kinase 1 0.1112 0.0634 0.2894
Brugia malayi integrin-linked kinase 0.0458 0.0031 0.0033
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.2251 0.1684 1
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis dual specificity 0.0809 0.0355 0.0353
Brugia malayi Protein kinase domain containing protein 1.0318 0.9124 0.9609
Entamoeba histolytica protein kinase, putative 0.0809 0.0355 0.1552
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Echinococcus multilocularis expressed conserved protein 0.0842 0.0385 0.0384
Brugia malayi Protein kinase domain containing protein 0.0864 0.0405 0.0427
Schistosoma mansoni serine/threonine kinase 0.1348 0.0852 0.2465
Echinococcus multilocularis raf serine:threonine protein kinase 0.0809 0.0355 0.0354
Toxoplasma gondii aurora kinase 0.1644 0.1125 0.6614
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) TK protein kinase 0.0458 0.0031 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0608 0.0169 0.1005
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Echinococcus multilocularis roundabout 2 0.0624 0.0184 0.0183
Brugia malayi hypothetical protein 0.0825 0.0369 0.0389
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.1472 0.0966 0.5654
Entamoeba histolytica hypothetical protein 0.2717 0.2114 1
Echinococcus granulosus serine:threonine protein kinase 0.0738 0.029 0.0322
Brugia malayi protein C17H12.11 0.0825 0.0369 0.0389
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.1012 0.0542 0.2453
Loa Loa (eye worm) hypothetical protein 0.1264 0.0774 0.0815
Schistosoma mansoni serine/threonine-protein kinase 0.1032 0.0561 0.1622
Brugia malayi Protein kinase domain containing protein 0.0608 0.0169 0.0178
Schistosoma mansoni atypical protein kinase C 0.2029 0.148 0.4283
Plasmodium falciparum protein serine/threonine kinase-1 0.2251 0.1684 1
Trichomonas vaginalis CMGC family protein kinase 0.0576 0.014 0.0832
Echinococcus granulosus expressed protein 0.0573 0.0137 0.0152
Giardia lamblia Kinase, STE STE20 0.1916 0.1375 0.8131
Brugia malayi cyclin-dependent kinase 7 homolog 0.1091 0.0615 0.0648
Loa Loa (eye worm) plexin A 0.0438 0.0013 0.0014
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.1012 0.0542 0.3091
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1199 0.0714 0.3376
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Giardia lamblia Kinase, CMGC GSK 0.1199 0.0714 0.4129
Toxoplasma gondii casein kinase I 0.1098 0.0621 0.3567
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0912 0.045 0.2531
Echinococcus granulosus casein kinase I alpha 0.1098 0.0621 0.0692
Loa Loa (eye worm) hypothetical protein 0.221 0.1647 0.1734
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0646 0.0205 0.0203
Entamoeba histolytica protein kinase domain containing protein 0.1199 0.0714 0.3277
Schistosoma mansoni protein kinase 0.1147 0.0666 0.1927
Echinococcus multilocularis insulin receptor 0.3634 0.296 0.2959
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.2761 0.2155 0.2269
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.0031 0.0033
Giardia lamblia Kinase, AGC AKT 0.162 0.1102 0.6479
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.1213 0.0728 0.0726
Plasmodium falciparum serine/threonine protein kinase KIN 0.0839 0.0383 0.2125
Brugia malayi Protein kinase domain containing protein 0.208 0.1527 0.1608
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0842 0.0385 0.0384
Plasmodium vivax serine/threonine kinase-1, putative 0.2251 0.1684 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.1012 0.0542 0.3091
Brugia malayi probable protein kinase 0.2521 0.1934 0.2037
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0489 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0441 0.0015 0.0016
Echinococcus multilocularis calcium activated potassium channel 0.0846 0.0389 0.0388
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.2717 0.2114 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.1547 0.1035 0.4818
Echinococcus granulosus cyclin dependent kinase 5 0.1112 0.0634 0.0707
Brugia malayi Immunoglobulin I-set domain containing protein 0.1264 0.0774 0.0815
Loa Loa (eye worm) AGC/PKG protein kinase 0.0842 0.0385 0.0406
Echinococcus multilocularis tyrosine protein kinase csk 0.0458 0.0031 0.003
Schistosoma mansoni tyrosine kinase 0.0751 0.0301 0.0872
Loa Loa (eye worm) AGC/NDR protein kinase 0.1213 0.0728 0.0766
Trichomonas vaginalis AGC family protein kinase 0.133 0.0835 0.4958
Echinococcus multilocularis tyrosine protein kinase Blk 0.1564 0.1051 0.105
Entamoeba histolytica protein kinase, putative 0.1644 0.1125 0.5248
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0756 0.0306 0.0322
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1012 0.0542 0.0541
Entamoeba histolytica protein kinase domain containing protein 0.1199 0.0714 0.3277
Echinococcus multilocularis serine:threonine protein kinase 38 0.1213 0.0728 0.0726
Brugia malayi protein kinase C II. 0.1571 0.1057 0.1113
Trypanosoma cruzi casein kinase, putative 0.1098 0.0621 0.2937
Echinococcus multilocularis cyclin dependent kinase 1 0.1112 0.0634 0.0633
Brugia malayi Variant SH3 domain containing protein 0.071 0.0263 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus cGMP dependent protein kinase 0.0842 0.0385 0.0429
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.1147 0.0666 0.0701
Entamoeba histolytica protein kinase, putative 0.1213 0.0728 0.3342
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.213 0.1573 0.74
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1916 0.1375 0.1448
Entamoeba histolytica protein kinase, putative 0.1012 0.0542 0.2453
Trichomonas vaginalis CAMK family protein kinase 0.074 0.0291 0.173
Brugia malayi serine/threonine-protein kinase plk-2 0.1551 0.1039 0.1095
Echinococcus granulosus ephrin type A receptor 4 A 0.0793 0.034 0.0378
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus granulosus c-Jun N-terminal kinases 0.4172 0.3456 0.3859
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.1127 0.0648 0.0682
Echinococcus granulosus casein kinase I delta 0.1098 0.0621 0.0692
Brugia malayi Protein kinase domain containing protein 0.1112 0.0634 0.0668
Echinococcus multilocularis tyrosine protein kinase csk 0.0458 0.0031 0.003
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Loa Loa (eye worm) hypothetical protein 0.2001 0.1454 0.1531
Brugia malayi Temporarily assigned gene name protein 59 0.1025 0.0554 0.0583
Brugia malayi casein kinase 1, delta 0.1098 0.0621 0.0654
Schistosoma mansoni neuroglian 0.0624 0.0184 0.0534
Trichomonas vaginalis AGC family protein kinase 0.0428 0.0003 0.0018
Echinococcus multilocularis tyrosine protein kinase HCK 0.1159 0.0677 0.0676
Trichomonas vaginalis CK1 family protein kinase 0.1098 0.0621 0.3687
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0031 0.0091
Echinococcus granulosus cyclin dependent kinase 9 0.0726 0.0278 0.0309
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0487 0.0058 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.2251 0.1684 0.4874
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni hypothetical protein 0.0441 0.0015 0.0043
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.074 0.0291 0.0324
Echinococcus granulosus homeodomain interacting protein kinase 3 0.1198 0.0713 0.0796
Schistosoma mansoni vesicular amine transporter 0.117 0.0687 0.1989
Echinococcus granulosus serine:threonine protein kinase MARK2 0.1273 0.0783 0.0873
Leishmania major protein kinase, putative 0.0581 0.0145 0.0544
Trichomonas vaginalis STE family protein kinase 0.0717 0.027 0.1603
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0957 0.0492 0.2784
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1869 0.1332 0.1331
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Entamoeba histolytica protein kinase domain containing protein 0.1644 0.1125 0.5248
Brugia malayi p70 ribosomal S6 kinase beta 0.186 0.1324 0.1394
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.1012 0.0542 0.3091
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0576 0.014 0.0523
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1254 0.0765 0.0853
Schistosoma mansoni protein kinase 0.1496 0.0988 0.286
Mycobacterium ulcerans hypothetical protein 0.0531 0.0098 0.5
Brugia malayi Protein kinase domain containing protein 0.0738 0.029 0.0305
Trichomonas vaginalis CMGC family protein kinase 0.0662 0.0219 0.1301
Trichomonas vaginalis conserved hypothetical protein 0.0458 0.0031 0.0186
Schistosoma mansoni protein kinase 0.0769 0.0318 0.0921
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Schistosoma mansoni protein kinase 0.0932 0.0468 0.1354
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.1025 0.0554 0.0553
Brugia malayi Sex muscle abnormal protein 5 0.071 0.0263 0.0277
Brugia malayi Protein kinase domain containing protein 0.0458 0.0031 0.0033
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0935 0.0471 0.0496
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Schistosoma mansoni tyrosine kinase 0.0458 0.0031 0.0091
Brugia malayi Protein kinase domain containing protein 0.1213 0.0728 0.0766
Trichomonas vaginalis CMGC family protein kinase 0.0809 0.0355 0.2105
Entamoeba histolytica protein kinase, putative 0.0573 0.0137 0.0508
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0864 0.0405 0.1794
Onchocerca volvulus 0.0458 0.0031 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.2339 0.1766 0.1859
Loa Loa (eye worm) hypothetical protein 0.2406 0.1828 0.1925
Echinococcus granulosus casein kinase I gamma 0.1253 0.0764 0.0853
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi Protein kinase domain containing protein 0.2251 0.1684 0.1774
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0769 0.0318 0.1505
Echinococcus multilocularis nervana 2 0.0646 0.0205 0.0203
Echinococcus granulosus tyrosine protein kinase Src42A 0.1136 0.0656 0.0732
Echinococcus multilocularis tyrosine protein kinase pr2 0.0458 0.0031 0.003
Echinococcus granulosus serine:threonine protein kinase mig 15 0.221 0.1647 0.1839
Plasmodium vivax glycogen synthase kinase 3, putative 0.1199 0.0714 0.4129
Brugia malayi STE20-like kinase MST 0.1481 0.0975 0.1026
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.1472 0.0966 0.0965
Echinococcus granulosus protein kinase c iota type 0.1997 0.1451 0.1619
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1869 0.1332 0.1331
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0662 0.0219 0.1136
Schistosoma mansoni protein kinase 0.1278 0.0787 0.2279
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0458 0.0031 0.0033
Echinococcus multilocularis protein kinase c epsilon type 0.1571 0.1057 0.1056
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1551 0.1039 0.1095
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0769 0.0318 0.1377
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis serine threonine protein kinase 0.1427 0.0925 0.0924
Trichomonas vaginalis TK family protein kinase 0.0458 0.0031 0.0186
Echinococcus multilocularis calcium dependent protein kinase 0.0701 0.0255 0.0254
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0809 0.0355 0.1956
Trichomonas vaginalis TKL family protein kinase 0.0458 0.0031 0.0186
Brugia malayi SRC-1 0.1869 0.1332 0.1403
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.2519 0.1931 0.193
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.1273 0.0783 0.0782
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.2807 0.2197 0.2453
Echinococcus granulosus activated cdc42 kinase 1 0.2524 0.1936 0.2162
Echinococcus multilocularis cyclin dependent kinase 5 0.1112 0.0634 0.0633
Schistosoma mansoni tyrosine kinase 0.3634 0.296 0.8566
Schistosoma mansoni serine/threonine protein kinase 0.0809 0.0355 0.1027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1564 0.1051 0.105
Trichomonas vaginalis CAMK family protein kinase 0.0839 0.0383 0.2272
Entamoeba histolytica protein kinase, putative 0.0509 0.0078 0.0224

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0089 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.122 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.1995 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5878 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 21.3313 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 79.4328 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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