Detailed information for compound 1365595

Basic information

Technical information
  • TDR Targets ID: 1365595
  • Name: 6-methoxy-7,8-dimethylpyrrolo[2,3-g][2,1,3]be nzoxadiazole
  • MW: 217.224 | Formula: C11H11N3O2
  • H donors: 0 H acceptors: 2 LogP: 2.42 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: COn1c(C)c(c2c1ccc1c2non1)C
  • InChi: 1S/C11H11N3O2/c1-6-7(2)14(15-3)9-5-4-8-11(10(6)9)13-16-12-8/h4-5H,1-3H3
  • InChiKey: AHNJIWWIKOVSFQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-methoxy-7,8-dimethyl-pyrrolo[2,3-g][2,1,3]benzoxadiazole
  • STOCK2S-11470
  • ZINC02296952
  • Oprea1_379529
  • CBMicro_026372
  • BIM-0026359.P001
  • 6-Methoxy-7,8-dimethyl-6H-2-oxa-1,3,6-triaza-as-indacene
  • MLS001012392
  • SMR000426920

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Human immunodeficiency virus 1 Aberrant vpr protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin glutathione reductase   598 aa 537 aa 24.2 %
Neospora caninum hypothetical protein Thioredoxin glutathione reductase   598 aa 485 aa 30.5 %
Neospora caninum glutathione reductase, putative Thioredoxin glutathione reductase   598 aa 532 aa 34.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin glutathione reductase   598 aa 513 aa 25.0 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin glutathione reductase   598 aa 512 aa 28.3 %
Onchocerca volvulus Thioredoxin glutathione reductase   598 aa 533 aa 50.8 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 518 aa 22.0 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 521 aa 21.5 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 538 aa 25.3 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin glutathione reductase   598 aa 555 aa 33.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Furin-like cysteine rich region family protein 0.066 0.0852 0.0852
Echinococcus granulosus mitogen activated protein kinase 3 0.0141 0.0061 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus twitchin 0.0228 0.0193 0.0604
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0651 0.0837 0.8775
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0248 0.0224 0.0224
Echinococcus multilocularis c Jun NH2 terminal kinase 0.033 0.0349 0.0892
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0286 0.0282 0.0282
Echinococcus granulosus serine:threonine protein kinase 3 0.0562 0.0702 0.2194
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Brugia malayi Cell division protein kinase 2 0.0129 0.0043 0.0043
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0273 0.0262 0.0262
Schistosoma mansoni protein kinase 0.0176 0.0115 0.036
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0229 0.0716
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Echinococcus granulosus c src tyrosine kinase 0.0169 0.0105 0.0327
Brugia malayi Variant SH3 domain containing protein 0.0121 0.0032 0.0032
Giardia lamblia Kinase, AGC PKA 0.0668 0.0863 0.8241
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0668 0.0863 0.9046
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0262 0.0245 0.0626
Brugia malayi C1-like domain containing protein 0.0427 0.0496 0.0496
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0668 0.0863 0.9046
Schistosoma mansoni tyrosine kinase 0.0262 0.0245 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0709 0.0926 0.2894
Entamoeba histolytica PH domain containing protein kinase, putative 0.0681 0.0884 0.3041
Trichomonas vaginalis CMGC family protein kinase 0.0787 0.1045 1
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0211 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0339 0.0363 0.1135
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.007 0.0219
Entamoeba histolytica protein kinase domain containing protein 0.0156 0.0085 0.0289
Leishmania major serine/threonine-protein kinase, putative 0.0106 0.0008 0.0078
Echinococcus granulosus tyrosine protein kinase Lyn 0.0349 0.0378 0.1181
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0358 0.3422
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0141 0.0061 0.063
Echinococcus multilocularis serine:threonine protein kinase 0.013 0.0045 0.0115
Loa Loa (eye worm) hypothetical protein 0.0279 0.0272 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.007 0.0219
Giardia lamblia Kinase, CK1 Casein kinase 0.0247 0.0223 0.2068
Echinococcus granulosus casein kinase I alpha 0.0247 0.0223 0.0696
Brugia malayi SRC-1 0.0262 0.0245 0.0245
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0129 0.0043 0.0109
Echinococcus granulosus nervana 2 0.013 0.0044 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0129 0.1226
Schistosoma mansoni serine/threonine-protein kinase 0.0231 0.0199 0.0622
Loa Loa (eye worm) TK protein kinase 0.0205 0.0159 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0138 0.0057 0.054
Echinococcus multilocularis PAK box P21 Rho binding 0.0154 0.0081 0.0206
Toxoplasma gondii NEK kinase 0.0106 0.0008 0.0078
Loa Loa (eye worm) TK/EGFR protein kinase 0.066 0.0852 0.0852
Echinococcus granulosus expressed protein 0.014 0.006 0.0188
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.014 0.006 0.006
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0129 0.0043 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0061 0.0575
Echinococcus granulosus tyrosine protein kinase Src42A 0.0156 0.0084 0.0262
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0176 0.0115 0.036
Giardia lamblia Kinase, NEK 0.0196 0.0145 0.1313
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.013 0.0045 0.0045
Trypanosoma brucei rac serine-threonine kinase, putative 0.0394 0.0447 0.4683
Schistosoma mansoni vam6/vps39 related 0.0354 0.0385 0.1204
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0194 0.0142 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0127 0.004 0.0126
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0336 0.0358 0.0916
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0262 0.0245 0.0626
Loa Loa (eye worm) CAMK protein kinase 0.0113 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.0385 0.1204
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.014 0.006 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0137 0.0428
Trypanosoma cruzi casein kinase, putative 0.0247 0.0223 0.2329
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0251 0.0229 0.0586
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Schistosoma mansoni protein kinase 0.0205 0.0159 0.0498
Trypanosoma brucei aurora B kinase 0.0205 0.0159 0.1663
Toxoplasma gondii NEK kinase 0.0106 0.0008 0.0078
Toxoplasma gondii CMGC kinase, CK2 family 0.0158 0.0087 0.0904
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0358 0.3422
Trichomonas vaginalis CMGC family protein kinase 0.0709 0.0926 0.8863
Echinococcus multilocularis mitogen activated protein kinase 11 0.022 0.0181 0.0463
Echinococcus granulosus tyrosine protein kinase Fyn 0.0262 0.0245 0.0765
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.014 0.006 0.0619
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0251 0.0229 0.0586
Brugia malayi Protein kinase domain containing protein 0.0273 0.0262 0.0262
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0347 0.0376 0.0961
Echinococcus granulosus homeodomain interacting protein kinase 3 0.2009 0.2903 0.907
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0222 0.0185 0.0579
Giardia lamblia Aurora kinase 0.0205 0.0159 0.1457
Brugia malayi P38 map kinase family protein 2 0.022 0.0181 0.0181
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0197 0.0147 0.1531
Echinococcus granulosus aurora kinase A 0.0205 0.0159 0.0498
Echinococcus multilocularis 0.0563 0.0704 0.18
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Entamoeba histolytica PH domain containing protein kinase, putative 0.0231 0.0198 0.0679
Loa Loa (eye worm) AGC/NDR protein kinase 0.0251 0.0229 0.0229
Trichomonas vaginalis CMGC family protein kinase 0.0651 0.0837 0.8006
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0466 0.0556 0.1736
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0191 0.0137 0.1427
Echinococcus granulosus neuroglian 0.014 0.006 0.0187
Trypanosoma brucei polo-like protein kinase 0.0336 0.0358 0.375
Schistosoma mansoni cell adhesion molecule 0.0142 0.0063 0.0196
Echinococcus multilocularis neuroglian 0.014 0.006 0.0153
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0147 0.007 0.0725
Echinococcus granulosus cGMP dependent protein kinase 0.0194 0.0142 0.0444
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0149 0.1418
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus tyrosine protein kinase Src64B 0.0262 0.0245 0.0765
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2207
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0571 0.0715 0.183
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Echinococcus multilocularis cyclin dependent kinase 7 0.0488 0.0589 0.1506
Echinococcus granulosus dual specificity 0.0199 0.0149 0.0466
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Schistosoma mansoni serine/threonine protein kinase 0.2204 0.3201 1
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0149 0.0074 0.025
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Loa Loa (eye worm) protein kinase domain-containing protein 0.0276 0.0267 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0112 0.0349
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Schistosoma mansoni kinase 0.0355 0.0388 0.1211
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0043 0.0399
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0147 0.007 0.0725
Trichomonas vaginalis AGC family protein kinase 0.0129 0.0043 0.0399
Loa Loa (eye worm) TK protein kinase 0.0296 0.0297 0.0297
Echinococcus multilocularis cyclin dependent kinase 1 0.0709 0.0926 0.237
Entamoeba histolytica PH domain containing protein kinase, putative 0.0231 0.0198 0.0679
Trypanosoma cruzi casein kinase, putative 0.0247 0.0223 0.2329
Onchocerca volvulus 0.0787 0.1045 0.3224
Echinococcus granulosus cyclin dependent kinase 5 0.0709 0.0926 0.2894
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0225 0.0704
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Schistosoma mansoni tyrosine kinase 0.0583 0.0734 0.2293
Echinococcus granulosus epidermal growth factor receptor 0.066 0.0852 0.2661
Echinococcus granulosus cGMP dependent protein kinase 1 0.0194 0.0142 0.0444
Leishmania major protein kinase A catalytic subunit isoform 2 0.0668 0.0863 0.9046
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0191 0.0137 0.1427
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0248 0.0224 0.0224
Trypanosoma cruzi casein kinase, putative 0.0247 0.0223 0.2329
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0205 0.0159 0.0498
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0205 0.0159 0.0546
Giardia lamblia Kinase, AGC AKT 0.0176 0.0114 0.102
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0651 0.0837 0.8775
Trichomonas vaginalis protein kinase atmrk1, putative 0.0129 0.0043 0.0399
Echinococcus multilocularis protein kinase c iota type 0.0398 0.0452 0.1157
Echinococcus multilocularis Immunoglobulin 0.012 0.003 0.0077
Brugia malayi Protein kinase domain containing protein 0.0651 0.0837 0.0837
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.013 0.0044 0.0137
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0262 0.0245 0.0626
Onchocerca volvulus Serine\/threonine kinase homolog 0.0225 0.0189 0.0533
Entamoeba histolytica SH2-protein kinase domain containing protein 0.013 0.0045 0.0152
Echinococcus multilocularis dual specificity protein kinase clk2 0.0651 0.0837 0.2141
Onchocerca volvulus 0.0327 0.0344 0.1021
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0466 0.0556 0.1421
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0141 0.0061 0.063
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0138 0.0057 0.0584
Trichomonas vaginalis CK1 family protein kinase 0.0247 0.0223 0.2125
Brugia malayi Protein kinase domain containing protein 0.0366 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0127 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.033 0.0349 0.1089
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0681 0.0884 0.0884
Echinococcus multilocularis calcium activated potassium channel 0.0249 0.0225 0.0576
Onchocerca volvulus 0.013 0.0045 0.008
Echinococcus multilocularis twitchin 0.0107 0.001 0.0025
Entamoeba histolytica protein kinase, putative 0.037 0.041 0.1411
Loa Loa (eye worm) TK protein kinase 0.0222 0.0185 0.0185
Schistosoma mansoni tyrosine kinase 0.066 0.0852 0.2661
Entamoeba histolytica protein kinase, putative 0.0167 0.0102 0.0347
Brugia malayi Protein kinase domain containing protein 0.0787 0.1045 0.1045
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0247 0.0223 0.0223
Schistosoma mansoni ste20-related kinase 0.0453 0.0536 0.1673
Brugia malayi Protein kinase domain containing protein 0.0138 0.0057 0.0057
Echinococcus multilocularis serine:threonine protein kinase N2 0.0251 0.0229 0.0586
Echinococcus granulosus serine:threonine kinase SAD 1 0.0147 0.007 0.0219
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Echinococcus multilocularis expressed protein 0.014 0.006 0.0154
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0194 0.0142 0.1481
Brugia malayi putative serine/threonine kinase SADA gamma 0.0147 0.007 0.007
Brugia malayi Protein kinase domain containing protein 0.2064 0.2988 0.2988
Trichomonas vaginalis AGC family protein kinase 0.0286 0.0283 0.2697
Plasmodium falciparum NIMA related kinase 1 0.0196 0.0145 0.1507
Echinococcus granulosus serine:threonine protein kinase NLK 0.0129 0.0043 0.0133
Loa Loa (eye worm) hypothetical protein 0.0205 0.0159 0.0159
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0651 0.0837 0.8775
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0449 0.053 0.1355
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0348 0.0376 0.0962
Echinococcus granulosus cyclin dependent kinase 7 0.0488 0.0589 0.184
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0106 0.0008 0.0078
Entamoeba histolytica protein kinase, putative 0.0727 0.0954 0.3282
Brugia malayi casein kinase I 0.0247 0.0223 0.0223
Echinococcus multilocularis Immunoglobulin 0.012 0.003 0.0077
Trypanosoma brucei NIMA-related protein kinase 0.0106 0.0008 0.0078
Brugia malayi Protein kinase domain 0.0176 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0279 0.0272 0.0272
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.022 0.0181 0.1891
Echinococcus multilocularis dual specificity 0.0199 0.0149 0.0381
Schistosoma mansoni protein kinase 0.0912 0.1235 0.3858
Echinococcus multilocularis mitogen activated protein kinase 11 0.022 0.0181 0.0463
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0263 0.0248 0.0248
Entamoeba histolytica protein kinase, putative 0.0199 0.0149 0.051
Loa Loa (eye worm) AUR protein kinase 0.0205 0.0159 0.0159
Trypanosoma brucei cdc2-related kinase 1 0.0709 0.0926 0.9715
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0336 0.0358 0.1119
Entamoeba histolytica hypothetical protein 0.037 0.041 0.1411
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0381 0.0426 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0043 0.0134
Plasmodium vivax unspecified product 0.0158 0.0087 0.0904
Trypanosoma cruzi polo-like protein kinase, putative 0.0336 0.0358 0.375
Echinococcus granulosus tyrosine kinase 0.0222 0.0185 0.0579
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Echinococcus multilocularis cyclin dependent kinase 19 0.0366 0.0403 0.1031
Trichomonas vaginalis CMGC family protein kinase 0.0727 0.0954 0.9124
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0339 0.0363 0.0929
Brugia malayi Protein kinase domain containing protein 0.013 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0218 0.0179 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.029 0.0906
Loa Loa (eye worm) hypothetical protein 0.0155 0.0083 0.0083
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.012 0.003 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0727 0.0954 0.3282
Echinococcus multilocularis CDC7 cell division cycle 7 0.0787 0.1045 0.2673
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0191 0.0137 0.1427
Echinococcus multilocularis protein kinase shaggy 0.0727 0.0954 0.2439
Trichomonas vaginalis CMGC family protein kinase 0.0709 0.0926 0.8863
Entamoeba histolytica protein kinase, putative 0.0394 0.0447 0.1537
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0061 0.063
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0185 0.0128 0.1221
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0129 0.0043 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.0589 0.184
Schistosoma mansoni protein kinase 0.0129 0.0043 0.0133
Leishmania major protein kinase, putative 0.0651 0.0837 0.8775
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0709 0.0926 0.2894
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2064 0.2988 0.7642
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.1115 0.3483
Echinococcus multilocularis serine:threonine protein kinase 38 0.0251 0.0229 0.0586
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Echinococcus multilocularis cyclin dependent kinase 1 0.0709 0.0926 0.237
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0191 0.0137 0.035
Trichomonas vaginalis AGC family protein kinase 0.0129 0.0043 0.0399
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0668 0.0863 0.9046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0191 0.0137 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0668 0.0863 0.2695
Brugia malayi Protein kinase domain containing protein 0.0276 0.0267 0.0267
Brugia malayi Protein kinase domain containing protein 0.049 0.0593 0.0593
Trichomonas vaginalis STE family protein kinase 0.0197 0.0147 0.1397
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0191 0.0137 0.0428
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.014 0.006 0.0619
Plasmodium vivax tyrosine kinase-like protein, putative 0.0138 0.0057 0.0584
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.6673 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Echinococcus granulosus insulin receptor 0.049 0.0593 0.1852
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0106 0.0008 0.0078
Loa Loa (eye worm) hypothetical protein 0.0136 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0353 0.0384 0.0384
Entamoeba histolytica protein kinase , putative 0.0205 0.0159 0.0546
Loa Loa (eye worm) hypothetical protein 0.0397 0.045 0.045
Trichomonas vaginalis AGC family protein kinase 0.0668 0.0863 0.8253
Trichomonas vaginalis STE family protein kinase 0.0176 0.0115 0.1094
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0291 0.029 0.0906
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0437 0.0512 0.0512
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0137 0.1302
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0159 0.1517
Echinococcus granulosus casein kinase i 0.0247 0.0223 0.0696
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0109 0.0013 0.0112
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2207
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0196 0.0145 0.1507
Schistosoma mansoni growth factor receptor-bound protein 0.0103 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.015 0.0076 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Echinococcus multilocularis insulin receptor 0.049 0.0593 0.1516
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.011 0.0015 0.0015
Brugia malayi Protein kinase domain containing protein 0.0912 0.1235 0.1235
Loa Loa (eye worm) hypothetical protein 0.0161 0.0092 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus activin receptor type 0.0156 0.0085 0.0265
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0668 0.0863 0.9046
Schistosoma mansoni titin 0.0113 0.002 0.0061
Echinococcus granulosus mitogen activated protein kinase 15 0.0129 0.0043 0.0133
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0129 0.0043 0.0437
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Brugia malayi protein kinase C II. 0.0312 0.0322 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0127 0.004 0.0104
Echinococcus granulosus protein kinase 0.0648 0.0834 0.2604
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2064 0.2988 0.2988
Echinococcus granulosus titin 0.0113 0.002 0.0061
Onchocerca volvulus 0.016 0.009 0.022
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0709 0.0926 0.9715
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0176 0.0114 0.0114
Schistosoma mansoni tyrosine kinase 0.0286 0.0282 0.0881
Echinococcus granulosus c-Jun N-terminal kinases 0.033 0.0349 0.1089
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0291 0.029 0.0741
Echinococcus multilocularis serine threonine protein kinase 0.0294 0.0294 0.0753
Echinococcus multilocularis cyclin dependent kinase 9 0.0363 0.04 0.1022
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0141 0.0061 0.063
Brugia malayi Cam kinase protein 1 0.0191 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.012 0.003 0.003
Trichomonas vaginalis CAMK family protein kinase 0.013 0.0045 0.0419
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0156 0.0085 0.0217
Echinococcus multilocularis calcium dependent protein kinase 0.0103 0.0004 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.002 0.0061
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0205 0.0159 0.0546
Echinococcus multilocularis cyclin dependent kinase 9 0.0322 0.0337 0.0862
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0194 0.0142 0.0363
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0176 0.0115 0.036
Brugia malayi Protein kinase domain containing protein 0.0709 0.0926 0.0926
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0061 0.063
Loa Loa (eye worm) hypothetical protein 0.0283 0.0277 0.0277
Schistosoma mansoni serine/threonine kinase 0.055 0.0684 0.2136
Brugia malayi Protein kinase domain containing protein 0.013 0.0045 0.0045
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0109 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0222 0.0185 0.0474
Echinococcus multilocularis casein kinase I delta 0.0247 0.0223 0.057
Schistosoma mansoni tyrosine kinase 0.0412 0.0473 0.1479
Echinococcus granulosus raf serine:threonine protein kinase 0.0129 0.0043 0.0134
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0129 0.0043 0.0437
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Echinococcus multilocularis casein kinase I alpha 0.0247 0.0223 0.057
Brugia malayi hypothetical protein 0.0286 0.0282 0.0282
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0709 0.0926 0.0926
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0322 0.0337 0.0337
Brugia malayi serine/threonine-protein kinase PAK 7 0.0685 0.0889 0.0889
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0727 0.0954 0.0954
Schistosoma mansoni tyrosine kinase 0.0276 0.0268 0.0836
Onchocerca volvulus 0.0279 0.0272 0.0793
Echinococcus multilocularis serine:threonine protein kinase 3 0.0562 0.0702 0.1796
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2695
Loa Loa (eye worm) CDC7 protein kinase 0.0787 0.1045 0.1045
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0384 0.1319
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0562 0.0702 0.0702
Brugia malayi STE20-like kinase MST 0.0562 0.0702 0.0702
Onchocerca volvulus 0.0247 0.0223 0.0639
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0041 0.0127
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Toxoplasma gondii casein kinase I 0.0247 0.0223 0.2329
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Brugia malayi Protein kinase domain containing protein 0.0251 0.0229 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Loa Loa (eye worm) hypothetical protein 0.0915 0.1239 0.1239
Trichomonas vaginalis AGC family protein kinase 0.0179 0.012 0.114
Brugia malayi Temporarily assigned gene name protein 59 0.0135 0.0052 0.0052
Schistosoma mansoni tyrosine kinase 0.0442 0.052 0.1625
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0286 0.0282 0.088
Loa Loa (eye worm) hypothetical protein 0.0145 0.0068 0.0068
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0156 0.0085 0.088
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0008 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0129 0.0043 0.0399
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0651 0.0837 0.8775
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0205 0.0158 0.0405
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0169 0.0105 0.0327
Entamoeba histolytica cell division protein kinase 2, putative 0.0751 0.0989 0.3404
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Echinococcus multilocularis dual specificity 0.0199 0.0149 0.0381
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0427 0.0496 0.0496
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0225 0.0704
Echinococcus granulosus dual specificity 0.0199 0.0149 0.0466
Echinococcus granulosus growth factor receptor bound protein 2 0.0103 0.0003 0.001
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0255 0.0235 0.0235
Echinococcus multilocularis serine:threonine protein kinase 0.013 0.0045 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0709 0.0926 0.2894
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0141 0.0061 0.0061
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0176 0.0115 0.0295
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0727 0.0954 0.0954
Loa Loa (eye worm) hypothetical protein 0.0155 0.0083 0.0083
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0912 0.1235 0.1235
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0156 0.0085 0.0265
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0262 0.0245 0.0626
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0149 0.1418
Schistosoma mansoni serine/threonine protein kinase 0.0286 0.0282 0.088
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2064 0.2988 0.933
Echinococcus multilocularis casein kinase ii subunit alpha 0.0158 0.0087 0.0223
Leishmania major protein kinase A catalytic subunit 0.0668 0.0863 0.9046
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0509 0.0621 0.0621
Plasmodium falciparum MO15-related protein kinase 0.0129 0.0043 0.0437
Echinococcus granulosus tyrosine protein kinase Src42A 0.0262 0.0245 0.0765
Brugia malayi probable protein kinase 0.1002 0.1372 0.1372
Echinococcus granulosus protein kinase c iota type 0.0398 0.0452 0.1413
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2695
Trichomonas vaginalis AGC family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus Vam6:Vps39 protein 0.0354 0.0385 0.1204
Schistosoma mansoni nephrin 0.0146 0.007 0.0217
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Loa Loa (eye worm) hypothetical protein 0.0354 0.0385 0.0385
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0262 0.0245 0.0626
Trypanosoma cruzi casein kinase, putative 0.0247 0.0223 0.2329
Schistosoma mansoni atypical protein kinase C 0.0404 0.0462 0.1444
Leishmania major protein kinase, putative 0.0156 0.0085 0.088
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0266 0.0252 0.0645
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0231 0.0198 0.2069
Plasmodium falciparum protein serine/threonine kinase-1 0.0651 0.0837 0.8775
Schistosoma mansoni protein kinase 0.0156 0.0085 0.0265
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0251 0.0229 0.0716
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.022 0.0181 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0787 0.1045 0.3265
Trypanosoma cruzi casein kinase, delta isoform, putative 0.016 0.009 0.093
Trypanosoma cruzi p21-activated kinase 3, putative 0.011 0.0015 0.0143
Echinococcus multilocularis casein kinase I alpha 0.0247 0.0223 0.057
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0197 0.0147 0.0503
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Trypanosoma cruzi cdc2-related kinase 3 0.0709 0.0926 0.9715
Loa Loa (eye worm) hypothetical protein 0.0198 0.0148 0.0148
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.0384 0.5
Trichomonas vaginalis CMGC family protein kinase 0.0727 0.0954 0.9124
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0109 0.0013 0.0112
Schistosoma mansoni tyrosine kinase 0.0442 0.052 0.1625
Echinococcus granulosus cyclin dependent kinase 9 0.0363 0.04 0.1248
Schistosoma mansoni serine/threonine protein kinase 0.0668 0.0863 0.2695
Echinococcus granulosus casein kinase I delta 0.0247 0.0223 0.0696
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0191 0.0137 0.1427
Echinococcus multilocularis aurora kinase A 0.0205 0.0159 0.0408
Plasmodium falciparum casein kinase 2, alpha subunit 0.0158 0.0087 0.0904
Echinococcus granulosus Glutaredoxin protein 5 0.013 0.0045 0.014
Plasmodium falciparum serine/threonine protein kinase 0.014 0.006 0.0619
Echinococcus multilocularis epidermal growth factor receptor 0.066 0.0852 0.2179
Echinococcus granulosus protein kinase shaggy 0.0727 0.0954 0.2979
Entamoeba histolytica casein kinase 1, putative 0.0247 0.0223 0.0764
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0138 0.0057 0.0179
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0523 0.0642 0.0642
Entamoeba histolytica protein kinase domain containing protein 0.037 0.041 0.1411
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.1115 0.2852
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0286 0.0282 0.072
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0266 0.0252 0.0788
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2064 0.2988 0.2988
Trichomonas vaginalis CK1 family protein kinase 0.0247 0.0223 0.2125
Entamoeba histolytica cell division protein kinase 2, putative 0.0709 0.0926 0.3189
Schistosoma mansoni serine/threonine protein kinase 0.0651 0.0837 0.2615
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0727 0.0954 0.2979
Schistosoma mansoni protein kinase 0.0775 0.1026 0.3205
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Trypanosoma cruzi cdc2-related kinase 1 0.0709 0.0926 0.9715
Brugia malayi cyclin-dependent kinase 7 homolog 0.0529 0.0651 0.0651
Schistosoma mansoni serine/threonine protein kinase 0.0466 0.0556 0.1736
Schistosoma mansoni serine/threonine protein kinase 0.1494 0.212 0.6623
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0247 0.0223 0.0223
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0427 0.0496 0.0496
Onchocerca volvulus 0.013 0.0045 0.008
Giardia lamblia Kinase, CMGC CK2 0.0158 0.0087 0.0759
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0159 0.1517
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis basement membrane specific heparan sulfate 0.012 0.003 0.0077
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0149 0.1418
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0651 0.0837 0.0837
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2695
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.037 0.041 0.4298
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0727 0.0954 1
Echinococcus granulosus mitogen activated protein kinase 11 0.022 0.0181 0.0566
Brugia malayi Protein kinase domain containing protein 0.0225 0.0189 0.0189
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0354 0.0385 0.4034
Giardia lamblia Kinase, NEK 0.0196 0.0145 0.1313
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0276 0.0268 0.0684
Echinococcus granulosus tyrosine protein kinase shark 0.0583 0.0734 0.2293
Echinococcus multilocularis tyrosine kinase 0.013 0.0045 0.0115
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0531 0.0655 0.0655
Trypanosoma brucei protein kinase, putative 0.0156 0.0085 0.088
Trypanosoma cruzi cdc2-related kinase 1 0.0709 0.0926 0.9715
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0651 0.0837 0.8775
Echinococcus granulosus mitogen activated protein kinase 14 0.022 0.0181 0.0566
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0197 0.0147 0.0503
Echinococcus granulosus tyrosine protein kinase ABL1 0.0347 0.0376 0.1173
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0217 0.0177 0.1849
Echinococcus multilocularis mitogen activated protein kinase 14 0.022 0.0181 0.0463
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis cyclin dependent kinase 5 0.0709 0.0926 0.237
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0262 0.0245 0.0765
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0262 0.0245 0.0765
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0622 0.0793 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0043 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0061 0.0575
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0912 0.1235 0.3858
Brugia malayi hypothetical protein 0.0354 0.0385 0.0385
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Brugia malayi Protein kinase domain containing protein 0.0255 0.0235 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Schistosoma mansoni protein kinase C mu 0.0427 0.0496 0.1551
Echinococcus multilocularis nervana 2 0.013 0.0044 0.0112
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0241 0.0213 0.0213
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0123 0.0034 0.0312
Trichomonas vaginalis AGC family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus cGMP dependent protein kinase 1 0.0194 0.0142 0.0444
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0466 0.0556 0.0556
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0709 0.0926 0.0926
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0358 0.3422
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Echinococcus granulosus casein kinase ii subunit alpha 0.0158 0.0087 0.0272
Schistosoma mansoni tyrosine kinase 0.049 0.0593 0.1852
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Echinococcus multilocularis titin 0.0113 0.002 0.005
Brugia malayi Protein kinase domain containing protein 0.0523 0.0642 0.0642
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.0421 0.4021
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0129 0.0043 0.0437
Trichomonas vaginalis STE family protein kinase 0.0176 0.0115 0.1094
Echinococcus multilocularis raf serine:threonine protein kinase 0.0129 0.0043 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Plasmodium falciparum serine/threonine protein kinase, putative 0.0205 0.0159 0.1663
Plasmodium falciparum glycogen synthase kinase 3 0.0727 0.0954 1
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Echinococcus granulosus tyrosine protein kinase Srms 0.0557 0.0695 0.217
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus cyclin dependent kinase 0.0709 0.0926 0.2894
Schistosoma mansoni tyrosine kinase 0.0104 0.0005 0.0014
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0129 0.0043 0.0437
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Onchocerca volvulus 0.0353 0.0384 0.1146
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0248 0.0224 0.0572
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0129 0.0043 0.0109
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0129 0.0043 0.0437
Schistosoma mansoni tyrosine kinase 0.0135 0.0052 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.001 0.0031
Giardia lamblia Kinase, STE STE20 0.0176 0.0115 0.1031
Schistosoma mansoni serine/threonine protein kinase 0.0558 0.0696 0.2176
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.029 0.0906
Entamoeba histolytica protein kinase, putative 0.037 0.041 0.1411
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0619 0.0789 0.2464
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0141 0.0061 0.063
Entamoeba histolytica protein kinase, putative 0.0192 0.0139 0.0475
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0127 0.0041 0.0104
Echinococcus multilocularis 0.0648 0.0834 0.2132
Trypanosoma brucei SNF1-related protein kinases, putative 0.0147 0.007 0.0725
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Plasmodium vivax serine/threonine protein kinase, putative 0.014 0.006 0.0619
Brugia malayi cell division control protein 2 homolog 0.0709 0.0926 0.0926
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0159 0.0498
Trypanosoma brucei cdc2-related kinase 3 0.0709 0.0926 0.9715
Plasmodium falciparum serine/threonine protein kinase KIN 0.0147 0.007 0.0725
Schistosoma mansoni serine/threonine protein kinase 0.014 0.006 0.0188
Trichomonas vaginalis STE family protein kinase 0.0106 0.0008 0.0071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0296 0.0297 0.0297
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0061 0.0191
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0223 0.0696
Loa Loa (eye worm) gastrulation defective protein 1 0.0278 0.027 0.027
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2207
Echinococcus granulosus calcium activated potassium channel 0.0249 0.0225 0.0704
Loa Loa (eye worm) TK/ALK protein kinase 0.0316 0.0328 0.0328
Echinococcus multilocularis N chimaerin 0.0121 0.0032 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0267 0.0835
Trichomonas vaginalis AGC family protein kinase 0.0138 0.0057 0.054
Loa Loa (eye worm) hypothetical protein 0.013 0.0045 0.0045
Loa Loa (eye worm) AUR protein kinase 0.0205 0.0159 0.0159
Trichomonas vaginalis serine/threonine kinase, putative 0.0129 0.0043 0.0399
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0727 0.0954 1
Trypanosoma cruzi cdc2-related kinase 3 0.0709 0.0926 0.9715
Schistosoma mansoni hypothetical protein 0.0354 0.0385 0.1204
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0106 0.0008 0.0078
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0552 0.0687 0.1757
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0354 0.0385 0.0986
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.011 0.0015 0.0143
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Echinococcus granulosus dual specificity protein kinase clk2 0.0651 0.0837 0.2615
Brugia malayi protein kinase C3,putative 0.0234 0.0203 0.0203
Giardia lamblia Kinase, CMGC SRPK 0.014 0.006 0.0498
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0619 0.0789 0.2017
Schistosoma mansoni hypothetical protein 0.0161 0.0092 0.0288
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0262 0.0245 0.0626
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0354 0.0385 0.1204
Echinococcus multilocularis 0.0182 0.0124 0.0316
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0488 0.0589 0.0589
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0113 0.002 0.002
Loa Loa (eye worm) AGC/AKT protein kinase 0.0394 0.0447 0.0447
Brugia malayi SH2 domain containing protein 0.013 0.0045 0.0045
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2064 0.2988 0.9334
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0109 1
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.0149 0.051
Loa Loa (eye worm) hypothetical protein 0.0145 0.0068 0.0068
Onchocerca volvulus 0.013 0.0045 0.008
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1086 0.1499 0.4685
Onchocerca volvulus 0.0354 0.0385 0.115
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0497 0.0602 0.1882
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.0322 0.1007
Entamoeba histolytica protein kinase, putative 0.0176 0.0115 0.0394
Echinococcus granulosus serine/threonine protein kinase 0.0231 0.0198 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.0337 0.1053
Loa Loa (eye worm) AGC/PKA protein kinase 0.0668 0.0863 0.0863
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.004 0.004
Giardia lamblia Kinase, PLK 0.0336 0.0358 0.3375
Echinococcus multilocularis tyrosine protein kinase Srms 0.0222 0.0185 0.0474
Toxoplasma gondii aurora kinase 0.0205 0.0159 0.1663
Giardia lamblia Kinase, CMGC GSK 0.0727 0.0954 0.9117
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0191 0.0137 0.1427
Entamoeba histolytica protein kinase 2, putative 0.0217 0.0177 0.0607
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0205 0.0159 0.0546
Echinococcus granulosus microtubule associated protein 2 0.0833 0.1115 0.3483
Schistosoma mansoni protein kinase 0.0156 0.0085 0.0265
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0149 0.0466
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0176 0.0115 0.0295
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0123 0.0034 0.0312
Echinococcus multilocularis ephrin type A receptor 4 A 0.0136 0.0054 0.0137
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0276 0.0268 0.0836
Loa Loa (eye worm) hypothetical protein 0.0339 0.0363 0.0363
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.002 0.002
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0262 0.2497
Echinococcus granulosus titin 0.0113 0.002 0.0061
Echinococcus multilocularis dual specificity 0.0199 0.0149 0.0381
Brugia malayi Protein kinase domain containing protein 0.0219 0.018 0.018
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0376 0.3591
Echinococcus multilocularis mitogen activated protein kinase 3 0.0141 0.0061 0.0156
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0197 0.0147 0.1531
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0189 0.0135 0.1407
Entamoeba histolytica PH domain containing protein kinase, putative 0.0681 0.0884 0.3041
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0106 0.0008 0.0078
Brugia malayi Protein kinase domain containing protein 0.0129 0.0043 0.0043
Echinococcus multilocularis activin receptor type 0.0156 0.0085 0.0217
Echinococcus multilocularis mitogen activated protein kinase 14 0.022 0.0181 0.0463
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Schistosoma mansoni tyrosine kinase 0.0374 0.0416 0.1298
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Schistosoma mansoni protein kinase 0.0775 0.1026 0.3205
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Brugia malayi Serine/threonine-protein kinase SULU 0.0286 0.0282 0.0282
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0367 0.0405 0.0405
Echinococcus multilocularis serine:threonine protein kinase N2 0.0411 0.0472 0.1207
Entamoeba histolytica protein kinase, putative 0.0251 0.0229 0.0786
Entamoeba histolytica protein kinase, putative 0.0161 0.0092 0.0313
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0191 0.0137 0.0137
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0156 0.0085 0.088
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.0687 0.2146
Trichomonas vaginalis STE family protein kinase 0.0176 0.0115 0.1094
Loa Loa (eye worm) hypothetical protein 0.0283 0.0277 0.0277
Echinococcus granulosus Immunoglobulin 0.012 0.003 0.0094
Onchocerca volvulus Tyrosine kinase homolog 0.0415 0.0479 0.1444
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0358 0.3422
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0205 0.0159 0.1663
Entamoeba histolytica protein kinase, putative 0.0205 0.0159 0.0546
Echinococcus granulosus calcium dependent protein kinase 0.0103 0.0004 0.0012
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0441 0.0519 0.162
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0156 0.0085 0.088
Leishmania major serine/threonine kinase-like protein, putative 0.0129 0.0043 0.0437
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0291 0.029 0.0741
Brugia malayi serine/threonine kinase 12 0.0205 0.0159 0.0159
Onchocerca volvulus 0.0339 0.0363 0.108
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0106 0.0008 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.037 0.041 0.1282
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0106 0.0008 0.0078
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0262 0.0245 0.0626
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Loa Loa (eye worm) hypothetical protein 0.0198 0.0148 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Schistosoma mansoni rap gtpase-activating protein 0.0354 0.0385 0.1204
Trypanosoma cruzi casein kinase, putative 0.0247 0.0223 0.2329
Brugia malayi protein unc-22 0.0113 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.0142 0.0444
Loa Loa (eye worm) AUR protein kinase 0.0205 0.0159 0.0159
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.011 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.0385 0.1204
Leishmania major protein kinase, putative 0.0651 0.0837 0.8775
Onchocerca volvulus 0.013 0.0045 0.008
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0571 0.0715 0.2235
Schistosoma mansoni protein kinase 0.0154 0.0081 0.0252
Entamoeba histolytica protein kinase, putative 0.0394 0.0447 0.1537
Brugia malayi serine/threonine-protein kinase 6 0.0205 0.0159 0.0159
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.0384 0.3622
Entamoeba histolytica protein kinase, putative 0.0127 0.0041 0.0136
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0191 0.0137 0.035
Echinococcus granulosus roundabout 2 0.0162 0.0093 0.029
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0191 0.0137 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0008 0.0071
Loa Loa (eye worm) hypothetical protein 0.0127 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0129 0.1226
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0121 0.0032 0.0099
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0222 0.0185 0.0474
Plasmodium falciparum NIMA related kinase 4 0.0106 0.0008 0.0078
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0336 0.0358 0.375
Plasmodium falciparum protein kinase, putative 0.0156 0.0085 0.088
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.037 0.041 0.4298
Echinococcus granulosus dual specificity 0.0199 0.0149 0.0466
Brugia malayi protein-tyrosine kinase 0.0222 0.0185 0.0185
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0121 0.0032 0.0081
Brugia malayi Protein kinase domain containing protein 0.0263 0.0248 0.0248
Giardia lamblia Kinase, AGC PKA 0.0217 0.0177 0.1628
Schistosoma mansoni Neurotrimin precursor (hNT) 0.012 0.003 0.0094
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Toxoplasma gondii NEK kinase 0.0106 0.0008 0.0078
Giardia lamblia Kinase, CMGC CDK 0.0709 0.0926 0.8855
Onchocerca volvulus 0.0787 0.1045 0.3224
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0915 0.1239 0.387
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0147 0.007 0.0725
Plasmodium falciparum cGMP-dependent protein kinase 0.0194 0.0142 0.1481
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Schistosoma mansoni protein kinase 0.0247 0.0223 0.0696
Toxoplasma gondii AGC kinase 0.0381 0.0426 0.4463
Brugia malayi Protein kinase domain containing protein 0.0681 0.0884 0.0884
Entamoeba histolytica p21-activated kinase 0.019 0.0136 0.0466
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0138 0.0057 0.0057
Echinococcus granulosus tyrosine protein kinase Fyn 0.0262 0.0245 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.0403 0.126
Trypanosoma brucei Casein kinase II 0.0158 0.0087 0.0904
Trypanosoma cruzi polo-like protein kinase, putative 0.0336 0.0358 0.375
Schistosoma mansoni protein kinase 0.0648 0.0834 0.2604
Brugia malayi Casein kinase II, alpha chain 0.0158 0.0087 0.0087
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0147 0.007 0.0179
Echinococcus granulosus tyrosine kinase 0.013 0.0045 0.0141
Echinococcus granulosus dual specificity 0.037 0.041 0.1282
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.2009 0.2903 0.7425
Brugia malayi Protein kinase domain containing protein 0.0681 0.0884 0.0884
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.013 0.0044 0.0112
Loa Loa (eye worm) hypothetical protein 0.0145 0.0068 0.0068
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.037 0.041 0.4298
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0043 0.0144
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0685 0.0889 0.0889
Schistosoma mansoni tyrosine kinase 0.0521 0.064 0.2001
Loa Loa (eye worm) TK/FER protein kinase 0.0266 0.0252 0.0252
Trypanosoma cruzi NIMA-related kinase, putative 0.0106 0.0008 0.0078
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0188 0.0133 0.1382
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0191 0.0137 0.1427
Echinococcus granulosus serine:threonine protein kinase N2 0.0411 0.0472 0.1474
Echinococcus multilocularis NCK adaptor protein 0.0103 0.0003 0.0008
Leishmania major casein kinase, putative 0.0247 0.0223 0.2329
Brugia malayi p70 ribosomal S6 kinase beta 0.0381 0.0426 0.0426
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0023 0.1705
Loa Loa (eye worm) TK/ABL protein kinase 0.0347 0.0376 0.0376
Echinococcus multilocularis Glutaredoxin protein 5 0.013 0.0045 0.0115
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0217 0.0177 0.1849
Entamoeba histolytica casein kinase, putative 0.0158 0.0087 0.0297
Loa Loa (eye worm) hypothetical protein 0.0121 0.0031 0.0031
Onchocerca volvulus 0.0127 0.004 0.0063
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0668 0.0863 0.9046
Echinococcus granulosus cyclin dependent kinase 19 0.0366 0.0403 0.126
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Leishmania major protein kinase, putative 0.0197 0.0147 0.1531
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0199 0.0149 0.1554
Loa Loa (eye worm) AGC/PKA protein kinase 0.0668 0.0863 0.0863
Entamoeba histolytica protein kinase domain containing protein 0.0727 0.0954 0.3282
Entamoeba histolytica protein kinase domain containing protein 0.0322 0.0337 0.1158
Entamoeba histolytica protein kinase, putative 0.0154 0.0081 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.0668 0.0863 0.2695
Onchocerca volvulus 0.2117 0.3068 0.9581
Brugia malayi map kinase activated protein kinase protein 2 0.0466 0.0556 0.0556
Echinococcus multilocularis rac serine:threonine kinase 0.0231 0.0198 0.0507
Leishmania major casein kinase II, putative 0.0158 0.0087 0.0904
Brugia malayi Protein kinase domain containing protein 0.013 0.0045 0.0045
Schistosoma mansoni tyrosine kinase 0.0169 0.0105 0.0327
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0205 0.0158 0.0495
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Brugia malayi Temporarily assigned gene name protein 59 0.0354 0.0385 0.0385
Echinococcus granulosus serine:threonine protein kinase 0.013 0.0045 0.014
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0199 0.0149 0.1554
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Schistosoma mansoni serine/threonine protein kinase 0.0651 0.0837 0.2615
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.058 0.073 0.2279
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0648 0.0834 0.0834
Schistosoma mansoni protein kinase 0.0176 0.0115 0.036
Brugia malayi Stress-activated protein kinase jnk-1 0.033 0.0349 0.0349
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0449 0.053 0.1655
Entamoeba histolytica hypothetical protein 0.0398 0.0453 0.1556
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0199 0.0149 0.1554
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Entamoeba histolytica protein kinase, putative 0.0149 0.0074 0.025
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0179 0.012 0.012
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0441 0.0519 0.1326
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0291 0.029 0.0906
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0262 0.0245 0.0626
Brugia malayi cyclin-dependent kinase 9 0.0322 0.0337 0.0337
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0775 0.1026 0.3205
Onchocerca volvulus 0.013 0.0045 0.008
Brugia malayi Protein kinase domain containing protein 0.014 0.006 0.006
Plasmodium falciparum calcium-dependent protein kinase 2 0.0191 0.0137 0.1427
Entamoeba histolytica protein kinase, putative 0.0167 0.0102 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0662 0.0854 0.2668
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0384 0.3668
Echinococcus multilocularis protein kinase c epsilon type 0.0312 0.0322 0.0824
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0199 0.0149 0.1554
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0354 0.0385 0.0986
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0197 0.0147 0.1531
Onchocerca volvulus 0.2204 0.3201 1
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.022 0.0181 0.1891
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0497 0.0602 0.1541
Echinococcus granulosus casein kinase I alpha 0.0247 0.0223 0.0696
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Echinococcus granulosus NDR protein kinase 0.0251 0.0229 0.0716
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0668 0.0863 0.9046
Toxoplasma gondii histone kinase SNF1, putative 0.0147 0.007 0.0725
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0709 0.0926 0.0926
Giardia lamblia Kinase, CMGC DYRK 0.0199 0.0149 0.1357
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0176 0.0115 0.0295
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.058 0.073 0.1866
Giardia lamblia Kinase, CDC7 0.0787 0.1045 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.0078 0.0078
Loa Loa (eye worm) TK/INSR protein kinase 0.049 0.0593 0.0593
Echinococcus multilocularis expressed conserved protein 0.0194 0.0142 0.0363
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0217 0.0177 0.0453
Schistosoma mansoni vav2 0.0135 0.0052 0.0164
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Brugia malayi Protein kinase domain containing protein 0.013 0.0045 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0159 0.1517
Brugia malayi RhoGAP domain containing protein 0.0121 0.0032 0.0032
Schistosoma mansoni tyrosine kinase 0.0262 0.0245 0.0765
Entamoeba histolytica casein kinase, putative 0.0247 0.0223 0.0764
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0121 0.0032 0.0032
Onchocerca volvulus Serine\/threonine kinase homolog 0.0336 0.0358 0.1065
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Plasmodium falciparum calcium-dependent protein kinase 1 0.0191 0.0137 0.1427
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0442 0.052 0.1625
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.022 0.0181 0.1891
Giardia lamblia Kinase, CMGC CLK 0.0651 0.0837 0.7992
Plasmodium falciparum calcium-dependent protein kinase 4 0.0191 0.0137 0.1427
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0276 0.0268 0.0684
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0159 0.1517
Echinococcus multilocularis death associated protein kinase 1 0.267 0.391 1
Echinococcus multilocularis dual specificity 0.037 0.041 0.105
Echinococcus granulosus casein kinase I delta 0.0247 0.0223 0.0696
Giardia lamblia Kinase, CMGC MAPK 0.0141 0.0061 0.0507
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0121 0.0032 0.0099
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0348 0.0376 0.1174
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0248 0.0224 0.0699
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.0142 0.0444
Brugia malayi Hr1 repeat family protein 0.0662 0.0854 0.0854
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0109 0.0013 0.0112
Entamoeba histolytica protein kinase, putative 0.014 0.006 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0668 0.0863 0.0863
Loa Loa (eye worm) AGC/PKG protein kinase 0.0194 0.0142 0.0142
Trypanosoma cruzi aurora B kinase, putative 0.0205 0.0159 0.1663
Plasmodium vivax calcium-dependent protein kinase, putative 0.0191 0.0137 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.2009 0.2903 1
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0106 0.0008 0.0078
Entamoeba histolytica serine/threonine protein kinase, putative 0.0147 0.007 0.0238
Loa Loa (eye worm) hypothetical protein 0.013 0.0045 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0348 0.0376 0.3591
Echinococcus granulosus N chimaerin 0.0121 0.0032 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0224 0.0699
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Brugia malayi Protein kinase domain containing protein 0.037 0.041 0.041
Echinococcus multilocularis tyrosine protein kinase HCK 0.0161 0.0092 0.0235
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0196 0.0145 0.1507
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0225 0.0704
Echinococcus multilocularis tyrosine protein kinase shark 0.0583 0.0734 0.1877
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.022 0.0181 0.1891
Echinococcus multilocularis casein kinase I gamma 0.0276 0.0267 0.0684
Trypanosoma brucei casein kinase I, isoform 2 0.0247 0.0223 0.2329
Brugia malayi Fes/CIP4 homology domain containing protein 0.0271 0.0259 0.0259
Schistosoma mansoni hypothetical protein 0.0161 0.0092 0.0288
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0339 0.0363 0.0363
Onchocerca volvulus 0.013 0.0045 0.008
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0043 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.007 0.0219
Loa Loa (eye worm) TK protein kinase 0.0161 0.0092 0.0092
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0681 0.0884 0.0884
Schistosoma mansoni protein kinase 0.1002 0.1372 0.4286
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0775 0.1026 0.2624
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Brugia malayi Fibronectin type III domain containing protein 0.0127 0.004 0.004
Brugia malayi serine/threonine protein kinase 6 0.0205 0.0159 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0358 0.3422
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0248 0.0773
Echinococcus multilocularis serine:threonine protein kinase N2 0.0662 0.0854 0.2184
Brugia malayi Protein kinase domain containing protein 0.0394 0.0447 0.0447
Brugia malayi serine/threonine-protein kinase plk-2 0.0336 0.0358 0.0358
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0023 0.1705
Loa Loa (eye worm) hypothetical protein 0.0127 0.004 0.004
Loa Loa (eye worm) AGC/PKN protein kinase 0.0662 0.0854 0.0854
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.013 0.0045 0.0045
Echinococcus multilocularis casein kinase I alpha 0.0247 0.0223 0.057
Loa Loa (eye worm) hypothetical protein 0.0354 0.0385 0.0385
Echinococcus granulosus tyrosine protein kinase HCK 0.0161 0.0092 0.0287
Schistosoma mansoni vesicular amine transporter 0.012 0.003 0.0094
Brugia malayi MAP kinase sur-1 0.0141 0.0061 0.0061
Brugia malayi Protein kinase domain containing protein 0.0317 0.0329 0.0329
Echinococcus multilocularis hypothetical protein 0.0161 0.0092 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0358 0.3422
Echinococcus multilocularis myosin iiia 0.0197 0.0147 0.0376
Echinococcus granulosus rho-associated protein kinase 1 0.2204 0.3201 1
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0199 0.0149 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Trypanosoma cruzi casein kinase II, putative 0.0158 0.0087 0.0904
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0354 0.0385 0.4034
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0156 0.0084 0.0214
Brugia malayi hypothetical protein 0.0127 0.004 0.004
Plasmodium falciparum calcium-dependent protein kinase 5 0.0191 0.0137 0.1427
Giardia lamblia Kinase, NEK 0.0196 0.0145 0.1313
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0354 0.0385 0.4034
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Echinococcus granulosus tyrosine protein kinase Blk 0.0222 0.0185 0.0579
Schistosoma mansoni tyrosine kinase 0.0374 0.0416 0.1298
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0251 0.0229 0.0716
Echinococcus granulosus ephrin type A receptor 4 A 0.0136 0.0054 0.0167
Loa Loa (eye worm) hypothetical protein 0.0125 0.0036 0.0036
Entamoeba histolytica protein kinase, putative 0.0138 0.0057 0.0194
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0149 0.1418
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0552 0.0687 0.2146
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0668 0.0863 0.9046
Brugia malayi Tyrosine-protein kinase abl-1 0.0134 0.0051 0.0051
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0127 0.0041 0.0127
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0312 0.0322 0.0322
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0912 0.1235 0.3158
Entamoeba histolytica protein kinase, putative 0.014 0.006 0.0203
Schistosoma mansoni ephrin receptor 0.0136 0.0054 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0196 0.0145 0.1375
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Toxoplasma gondii AGC kinase 0.0668 0.0863 0.9046
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.0687 0.2146
Echinococcus multilocularis mitogen activated protein kinase 0.0141 0.0061 0.0156
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.011 0.0015 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0138 0.0057 0.0584
Loa Loa (eye worm) casein kinase 0.0189 0.0134 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0292 0.0292 0.2784
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0191 0.0137 0.0137
Echinococcus granulosus hypothetical protein 0.0563 0.0704 0.2198
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0668 0.0863 0.9046
Schistosoma mansoni tyrosine kinase 0.049 0.0593 0.1852
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0015 0.0046
Plasmodium vivax casein kinase 1, putative 0.0247 0.0223 0.2329
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0339 0.0363 0.1135
Schistosoma mansoni kinase 0.0322 0.0337 0.1053
Loa Loa (eye worm) haspin protein kinase 0.0129 0.0043 0.0043
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0336 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0101 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0272 0.0261 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Loa Loa (eye worm) hypothetical protein 0.0191 0.0137 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0061 0.0575
Brugia malayi intracellular kinase 0.0727 0.0954 0.0954
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0366 0.0403 0.0403
Brugia malayi Protein kinase domain containing protein 0.013 0.0045 0.0045
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.014 0.006 0.0619
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0008 0.0071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0531 0.0655 0.0655
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0191 0.0137 0.1427
Echinococcus granulosus fibroblast growth factor receptor 4 0.0276 0.0268 0.0836
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Echinococcus multilocularis rho associated protein kinase 0.2204 0.3201 0.8187
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0225 0.0189 0.0591
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0217 0.0177 0.1849
Giardia lamblia Kinase, CAMK CAMKL 0.0188 0.0133 0.1198
Loa Loa (eye worm) hypothetical protein 0.0147 0.007 0.007
Entamoeba histolytica protein kinase, putative 0.0191 0.0137 0.0468
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0668 0.0863 0.9046
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0584 0.0736 0.0736
Brugia malayi Egg laying defective protein 4 0.0194 0.0142 0.0142
Echinococcus granulosus CDC7 cell division cycle 7 0.0787 0.1045 0.3265
Entamoeba histolytica protein kinase, putative 0.0381 0.0426 0.1465
Loa Loa (eye worm) SRC-1 0.0262 0.0245 0.0245
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.2009 0.2903 0.2903
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0584 0.0736 0.0736
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0727 0.0954 0.2979
Plasmodium vivax protein kinase Crk2 0.0709 0.0926 0.9715
Plasmodium falciparum calcium-dependent protein kinase 3 0.0191 0.0137 0.1427
Giardia lamblia Kinase, STE STE20 0.0197 0.0147 0.1336
Echinococcus granulosus Protein kinase C brain isozyme 0.0354 0.0385 0.1204
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0147 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0354 0.0385 0.0385
Echinococcus granulosus nervana 2 0.013 0.0044 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0149 0.1418
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0709 0.0926 0.9715
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0136 0.0053 0.0166
Schistosoma mansoni protein kinase 0.0156 0.0085 0.0265
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0651 0.0837 0.8775
Loa Loa (eye worm) thyroid receptor interactor 0.0271 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.012 0.003 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0008 0.0026
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0354 0.0385 0.1204
Schistosoma mansoni protein kinase 0.0158 0.0087 0.0272
Schistosoma mansoni protein kinase 0.0775 0.1026 0.3205
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0023 0.1705
Trichomonas vaginalis STE family protein kinase 0.0154 0.0081 0.0763
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2064 0.2988 0.2988
Echinococcus granulosus cyclin dependent kinase 1 0.0709 0.0926 0.2894
Brugia malayi Protein kinase domain containing protein 0.0509 0.0621 0.0621
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0106 0.0008 0.0078
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0129 0.0043 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.0589 0.184
Leishmania major protein kinase, putative 0.0191 0.0137 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.0158 0.0087 0.0297
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0176 0.0115 0.036
Echinococcus granulosus mitogen activated protein kinase 0.0141 0.0061 0.0191
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0121 0.0032 0.0099
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0262 0.0245 0.0626
Giardia lamblia Kinase, CAMK CAMKL 0.0188 0.0133 0.1198
Echinococcus granulosus protein kinase C gamma type 0.0294 0.0294 0.092
Onchocerca volvulus 0.0727 0.0954 0.2936
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.007 0.0661
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0034 0.0312
Onchocerca volvulus 0.0145 0.0068 0.0152
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0156 0.0085 0.088
Trichomonas vaginalis CK1 family protein kinase 0.0247 0.0223 0.2125
Echinococcus granulosus cyclin dependent kinase 9 0.0322 0.0337 0.1053
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0668 0.0863 0.9046
Brugia malayi Homeodomain interacting protein kinase protein 1 0.2009 0.2903 0.2903
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0158 0.0087 0.0904
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0447 0.4272
Brugia malayi SH2 domain containing protein 0.0266 0.0252 0.0252
Echinococcus multilocularis cyclin dependent kinase 0.0709 0.0926 0.237
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0247 0.0223 0.2329
Echinococcus multilocularis c src tyrosine kinase 0.0169 0.0105 0.0268
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0205 0.0159 0.0408
Brugia malayi Protein kinase domain containing protein 0.0118 0.0026 0.0026
Echinococcus granulosus serine:threonine protein kinase N2 0.0662 0.0854 0.2668
Plasmodium vivax glycogen synthase kinase 3, putative 0.0727 0.0954 1
Schistosoma mansoni tyrosine kinase 0.0169 0.0105 0.0327
Echinococcus multilocularis casein kinase i 0.0247 0.0223 0.057
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0247 0.0223 0.0223
Trichomonas vaginalis CMGC family protein kinase 0.0709 0.0926 0.8863
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.011 0.0015 0.0131
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0354 0.0385 0.1204
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0061 0.0575
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0141 0.0061 0.063
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0141 0.0061 0.063
Schistosoma mansoni serine/threonine-protein kinase 0.0231 0.0198 0.0619
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.033 0.0349 0.0349
Echinococcus multilocularis epidermal growth factor receptor 0.0442 0.052 0.1331
Schistosoma mansoni serine/threonine protein kinase 0.2064 0.2988 0.9334
Brugia malayi casein kinase 1, delta 0.0247 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0668 0.0863 0.0863
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0109 1
Loa Loa (eye worm) hypothetical protein 0.0483 0.0582 0.0582
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0087 0.0825
Loa Loa (eye worm) TK/FER protein kinase 0.013 0.0045 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.2009 0.2903 0.907
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0727 0.0954 0.2439
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0225 0.0189 0.0189
Trichomonas vaginalis STE family protein kinase 0.0176 0.0115 0.1094
Trichomonas vaginalis STE family protein kinase 0.0196 0.0145 0.1375
Giardia lamblia Kinase, CMGC CDK 0.0709 0.0926 0.8855
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0129 0.0043 0.0437
Trichomonas vaginalis CAMK family protein kinase 0.0509 0.0621 0.5938
Plasmodium falciparum NIMA related kinase 2 0.0106 0.0008 0.0078
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0384 0.1319
Brugia malayi Doublecortin family protein 0.0211 0.0168 0.0168
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0727 0.0954 1
Brugia malayi hypothetical protein 0.013 0.0045 0.0045
Brugia malayi Tyrosine-protein kinase abl-1 0.0252 0.0231 0.0231
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0023 0.1705
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0709 0.0926 0.9715
Echinococcus granulosus epidermal growth factor receptor 0.0442 0.052 0.1625
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0358 0.1119
Echinococcus granulosus casein kinase I gamma 0.0276 0.0267 0.0835
Echinococcus granulosus serine threonine protein kinase nrc 0.0217 0.0177 0.0554
Leishmania major protein kinase A catalytic subunit isoform 1 0.0668 0.0863 0.9046
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.037 0.041 0.041
Plasmodium falciparum protein kinase 5 0.0709 0.0926 0.9715
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0191 0.0137 0.0428
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Echinococcus multilocularis nervana 2 0.013 0.0044 0.0112
Brugia malayi Protein kinase c protein 2 0.019 0.0136 0.0136
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0129 0.0043 0.0399
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0225 0.0189 0.0484
Trichomonas vaginalis CMGC family protein kinase 0.0787 0.1045 1
Brugia malayi Kinase associated domain 1 family protein 0.0161 0.0092 0.0092
Entamoeba histolytica protein kinase, putative 0.0205 0.0159 0.0546
Schistosoma mansoni protein kinase 0.0255 0.0235 0.0734
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0043 0.0399
Entamoeba histolytica serine/threonine protein kinase, putative 0.0336 0.0358 0.1231
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0147 0.007 0.0725
Giardia lamblia Kinase, CAMK CAMKL 0.0129 0.0043 0.0331
Plasmodium vivax serine/threonine kinase-1, putative 0.0651 0.0837 0.8775
Trypanosoma brucei protein kinase, putative 0.0182 0.0124 0.1287
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0057 0.0179
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0147 0.007 0.0725
Echinococcus granulosus casein kinase I alpha 0.0247 0.0223 0.0696
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0191 0.0137 0.0428
Trypanosoma brucei protein kinase, putative 0.0727 0.0954 1
Leishmania major protein kinase, putative 0.0205 0.0159 0.1663
Echinococcus multilocularis tyrosine protein kinase Abl 0.0252 0.0231 0.0591
Giardia lamblia Kinase, CMGC GSK 0.0727 0.0954 0.9117
Entamoeba histolytica protein kinase, putative 0.0127 0.0041 0.0136
Loa Loa (eye worm) hypothetical protein 0.0681 0.0884 0.0884
Trichomonas vaginalis CMGC family protein kinase 0.0787 0.1045 1
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Echinococcus multilocularis casein kinase I delta 0.0247 0.0223 0.057
Brugia malayi phosphoinositide-dependent protein kinase I 0.0138 0.0057 0.0057
Plasmodium falciparum casein kinase 1 0.0247 0.0223 0.2329
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0229 0.0716
Entamoeba histolytica protein kinase domain containing protein 0.0205 0.0159 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0008 0.0071
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0199 0.0149 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0149 0.1418
Loa Loa (eye worm) TK/EPH protein kinase 0.0154 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.013 0.0045 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.007 0.0219
Echinococcus granulosus tyrosine protein kinase Fyn 0.0262 0.0245 0.0765
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0043 0.0399
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.037 0.041 0.4298
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0217 0.0177 0.0554
Toxoplasma gondii AGC kinase 0.0668 0.0863 0.9046
Leishmania major protein kinase, putative 0.0106 0.0008 0.0078
Echinococcus multilocularis roundabout 2 0.0162 0.0093 0.0237
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0158 0.0087 0.0087
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0651 0.0837 0.8775
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0008 0.0071
Schistosoma mansoni tyrosine kinase 0.0374 0.0416 0.1298
Schistosoma mansoni serine/threonine kinase 0.0251 0.0229 0.0716
Loa Loa (eye worm) hypothetical protein 0.0563 0.0704 0.0704
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0668 0.0863 0.2207
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0013 0.0112
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0262 0.2497
Trypanosoma cruzi Protein kinase B 0.0231 0.0198 0.2069
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0189 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0015 0.0046
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0138 0.0057 0.0147
Echinococcus granulosus protein kinase c epsilon type 0.0312 0.0322 0.1007
Echinococcus granulosus defective proboscis extension response 0.012 0.003 0.0094
Echinococcus granulosus serine:threonine protein kinase 0.013 0.0045 0.014

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 3.5397 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 3.5481 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 14.1254 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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