Detailed information for compound 1385459

Basic information

Technical information
  • TDR Targets ID: 1385459
  • Name: 5-[(4-methylphenyl)methyl]-3H-pyridazino[4,5- b]indol-4-one
  • MW: 289.331 | Formula: C18H15N3O
  • H donors: 1 H acceptors: 3 LogP: 3.2 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)Cn1c2ccccc2c2c1c(O)nnc2
  • InChi: 1S/C18H15N3O/c1-12-6-8-13(9-7-12)11-21-16-5-3-2-4-14(16)15-10-19-20-18(22)17(15)21/h2-10H,11H2,1H3,(H,20,22)
  • InChiKey: LTVXVRZXFLIBDO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-(4-methylbenzyl)-3H-pyridazino[4,5-b]indol-4-one
  • ChemDiv3_010995
  • IDI1_028553
  • MLS000119675
  • SMR000096596

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Bacillus subtilis (strain 168) ATP-dependent Clp protease proteolytic subunit Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus peptidase Clp S14 family Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum ATP-dependent Clp protease proteolytic subunit, related Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis ATP-dependent Clp protease proteolytic subunit 1, putative Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127187 All targets in OG5_127187
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum ko:K01358 ATP-dependent Clp protease, protease subunit [EC3.4.21.92], putative Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii ATP-dependent Clp protease, proteolytic subunit ClpP, putative Get druggable targets OG5_127187 All targets in OG5_127187
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K06275 parvin, putative Get druggable targets OG5_127187 All targets in OG5_127187
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Probable ClpP-like protease Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Treponema pallidum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Chlamydia trachomatis hypothetical protein ATP-dependent Clp protease proteolytic subunit   197 aa 171 aa 22.8 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.1 %
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 180 aa 36.7 %
Treponema pallidum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 186 aa 40.3 %
Schistosoma mansoni neuropeptide receptor ATP-dependent Clp protease proteolytic subunit   197 aa 174 aa 20.1 %
Onchocerca volvulus Putative V-type proton ATPase subunit F ATP-dependent Clp protease proteolytic subunit   197 aa 194 aa 54.1 %
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 35.5 %
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 36.0 %
Plasmodium yoelii Clp protease ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.6 %
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 ATP-dependent Clp protease proteolytic subunit   197 aa 172 aa 57.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tyrosine-protein kinase abl-1 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Schistosoma mansoni zinc finger protein 0.0042 0.0058 0.0058
Echinococcus granulosus oxysterol binding protein 1 0.0042 0.0058 0.0069
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0053 0.0099 0.0643
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Schistosoma mansoni hypothetical protein 0.0248 0.08 0.08
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0064 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Onchocerca volvulus 0.0039 0.0047 0.0206
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.005 0.0088 0.3558
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0042 0.0058 0.0058
Brugia malayi Dynamin 0.0042 0.0058 0.0058
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0058 0.0376
Echinococcus multilocularis plexin a4 0.0689 0.2384 0.2851
Brugia malayi RNA binding protein 0.0076 0.0183 0.0183
Onchocerca volvulus 0.0042 0.0058 0.0263
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis calcium dependent secretion activator 1 0.0042 0.0058 0.0069
Trichomonas vaginalis centaurin alpha, putative 0.0042 0.0058 0.0376
Schistosoma mansoni hypothetical protein 0.0042 0.0058 0.0058
Trichomonas vaginalis protein transport protein sec7, putative 0.0042 0.0058 0.0376
Giardia lamblia Kinase, NEK 0.0039 0.0047 0.2799
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Brugia malayi Tyrosine-protein kinase PR2 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0088 0.0569
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0072 0.0167 0.1083
Loa Loa (eye worm) hypothetical protein 0.0084 0.0208 0.0208
Brugia malayi protein-tyrosine kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0047 0.0303
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Onchocerca volvulus 0.0042 0.0058 0.0263
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0109 0.0299 0.0299
Echinococcus multilocularis Immunoglobulin 0.0079 0.0191 0.0229
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0072 0.0167 0.1083
Echinococcus multilocularis actin binding protein anillin 0.0042 0.0058 0.0069
Loa Loa (eye worm) TK/ROR protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0039 0.0047 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0047 0.0047
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.2354 0.8364 0.8364
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Entamoeba histolytica serine/threonine kinase, putative 0.0039 0.0047 0.0303
Echinococcus granulosus tyrosine protein kinase ABL1 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0043 0.0064 0.0076
Loa Loa (eye worm) hypothetical protein 0.0248 0.08 0.08
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0025 0.1004
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0099 0.0643
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0009 0.0061
Echinococcus granulosus tyrosine protein kinase Srms 0.0039 0.0047 0.0056
Echinococcus granulosus calcium dependent secretion activator 1 0.0042 0.0058 0.0069
Loa Loa (eye worm) hypothetical protein 0.0079 0.0191 0.0191
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0039 0.0047 0.0056
Echinococcus granulosus regulator of G protein signaling 3 0.0456 0.1544 0.1846
Echinococcus granulosus Oxysterol binding protein 11 0.0042 0.0058 0.0069
Trichomonas vaginalis centaurin beta, putative 0.0042 0.0058 0.0376
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Brugia malayi Sema domain containing protein 0.0248 0.08 0.08
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0109 0.0299 0.0299
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.0247 1
Echinococcus granulosus DCC interacting protein 13 beta 0.0042 0.0058 0.0069
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0039 0.0047 0.0047
Echinococcus granulosus oxysterol binding protein 3 0.0042 0.0058 0.0069
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.0247 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0039 0.0047 0.0303
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Entamoeba histolytica tyrosin kinase, putative 0.0039 0.0047 0.0303
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0247 1
Leishmania major folate/biopterin transporter, putative 0.0053 0.0099 0.5935
Brugia malayi TAR-binding protein 0.0076 0.0183 0.0183
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0042 0.0058 0.3474
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0064 0.0076
Echinococcus granulosus dynamin 1 0.0042 0.0058 0.0069
Schistosoma mansoni hypothetical protein 0.0042 0.0058 0.0058
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis MAM 0.0027 0.0006 0.0007
Plasmodium vivax tyrosine kinase-like protein, putative 0.0039 0.0047 0.1893
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0042 0.0058 0.0058
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0109 0.0299 0.1935
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica tyrosin kinase, putative 0.0147 0.0438 0.2834
Loa Loa (eye worm) PH domain-containing protein 0.0042 0.0058 0.0058
Schistosoma mansoni regulator of G protein signaling 0.0456 0.1544 0.1544
Entamoeba histolytica hypothetical protein 0.0109 0.0299 0.1935
Brugia malayi jmjC domain containing protein 0.0071 0.0163 0.0163
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0906 1
Brugia malayi Variant SH3 domain containing protein 0.0042 0.0058 0.0058
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus granulosus retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Schistosoma mansoni protein kinase 0.005 0.0088 0.0088
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Echinococcus granulosus c src tyrosine kinase 0.0039 0.0047 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Brugia malayi beta-lactamase family protein 0.0043 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0052 0.0093 0.0093
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0058 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0058 0.0376
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0042 0.0058 0.0376
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0039 0.0047 0.0303
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0042 0.0058 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0039 0.0047 0.0056
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.0247 0.0247
Onchocerca volvulus 0.0039 0.0047 0.0206
Entamoeba histolytica receptor protein kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0039 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase Src64B 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica serine/threonine kinase, putative 0.0039 0.0047 0.0303
Trypanosoma cruzi protein kinase, putative 0.0039 0.0047 0.2799
Giardia lamblia Kinase, NEK 0.0039 0.0047 0.2799
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0053 0.0099 0.5935
Trypanosoma brucei rac serine-threonine kinase, putative 0.0053 0.0099 0.5935
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Echinococcus multilocularis transfer RNA-Thr 0.0039 0.0047 0.0056
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0042 0.0058 0.235
Toxoplasma gondii ABC1 family protein 0.0043 0.0064 0.2594
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) PXA domain-containing protein 0.0456 0.1544 0.1544
Entamoeba histolytica p21-activated kinase 0.0053 0.0099 0.0643
Echinococcus granulosus activin receptor type 0.005 0.0088 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0053 0.0099 0.5935
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0053 0.0099 0.5935
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Schistosoma mansoni tyrosine protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0039 0.0047 0.0056
Onchocerca volvulus 0.0043 0.0064 0.0293
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Echinococcus multilocularis axis inhibition protein axin 0.0456 0.1544 0.1846
Echinococcus granulosus semaphorin 1A 0.0248 0.08 0.0956
Echinococcus granulosus Regulator of G protein signaling 20 0.0456 0.1544 0.1846
Loa Loa (eye worm) hypothetical protein 0.0456 0.1544 0.1544
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/EGFR protein kinase 0.0039 0.0047 0.0047
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0053 0.0099 0.5935
Entamoeba histolytica serine/threonine kinase, putative 0.0039 0.0047 0.0303
Echinococcus granulosus aurora kinase A 0.0072 0.0167 0.02
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 1
Brugia malayi hypothetical protein 0.0248 0.08 0.08
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Loa Loa (eye worm) sema domain-containing protein 0.0248 0.08 0.08
Schistosoma mansoni regulator of G protein signaling 0.0456 0.1544 0.1544
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1698 0.6008 0.7183
Schistosoma mansoni centaurin alpha 0.0042 0.0058 0.0058
Entamoeba histolytica hypothetical protein 0.0109 0.0299 0.1935
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0109 0.0299 0.1935
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi serine/threonine kinase 12 0.0072 0.0167 0.0167
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0058 0.3474
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Leishmania major serine/threonine-protein kinase a, putative 0.0053 0.0099 0.5935
Trichomonas vaginalis TK family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Trypanosoma brucei Flagellum attachment zone protein 20 0.0039 0.0047 0.2799
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) AGC/AKT protein kinase 0.0053 0.0099 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.281 1 1
Onchocerca volvulus 0.0039 0.0047 0.0206
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0072 0.0167 0.6765
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0053 0.0099 0.5935
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Echinococcus multilocularis aurora kinase A 0.0072 0.0167 0.02
Plasmodium falciparum oxysterol-binding protein, putative 0.0042 0.0058 0.235
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Brugia malayi Guanylyl cyclase protein 23 0.0039 0.0047 0.0047
Echinococcus multilocularis oxysterol binding protein 3 0.0042 0.0058 0.0069
Leishmania major hypothetical protein, conserved 0.0039 0.0047 0.2799
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0043 0.0043
Echinococcus multilocularis tyrosine kinase 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0109 0.0299 0.0299
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0167 0.0167
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus epidermal growth factor receptor 0.0039 0.0047 0.0056
Echinococcus multilocularis tyrosine kinase 0.0039 0.0047 0.0056
Brugia malayi PXA domain containing protein 0.0456 0.1544 0.1544
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0053 0.0099 0.5935
Schistosoma mansoni growth factor receptor-bound protein 0.0042 0.0058 0.0058
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Echinococcus multilocularis c src tyrosine kinase 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0085 0.0215 0.0215
Entamoeba histolytica serine/threonine kinase, putative 0.0039 0.0047 0.0303
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0043 0.0064 0.0076
Loa Loa (eye worm) hypothetical protein 0.0084 0.0208 0.0208
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Giardia lamblia Aurora kinase 0.0072 0.0167 1
Entamoeba histolytica hypothetical protein 0.0042 0.0058 0.0376
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0099 0.0643
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0064 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis tyrosine protein kinase HCK 0.0039 0.0047 0.0056
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0099 0.0643
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.033 0.033
Echinococcus granulosus myotubularin protein 13 0.0042 0.0058 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0247 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0006 0.0007
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0042 0.0058 0.0376
Entamoeba histolytica PH domain containing protein 0.0042 0.0058 0.0376
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Schistosoma mansoni regulator of G protein signaling 0.0456 0.1544 0.1544
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni hypothetical protein 0.0042 0.0058 0.0058
Echinococcus granulosus tyrosine kinase 0.0039 0.0047 0.0056
Plasmodium falciparum serine/threonine protein kinase, putative 0.0072 0.0167 0.6765
Echinococcus granulosus tyrosine kinase 0.0039 0.0047 0.0056
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Trichomonas vaginalis protein tyrosine kinase, putative 0.0039 0.0047 0.0303
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 0.5
Echinococcus multilocularis Ras associated and pleckstrin y 0.0042 0.0058 0.0069
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Schistosoma mansoni serine/threonine protein kinase 0.2154 0.7644 0.7644
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0039 0.0047 0.2799
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0072 0.0167 0.02
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0034 0.0221
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0167 0.1083
Leishmania major protein kinase, putative 0.005 0.0088 0.526
Loa Loa (eye worm) hypothetical protein 0.0456 0.1544 0.1544
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus granulosus Rho GTPase activating protein 24 0.0042 0.0058 0.0069
Plasmodium vivax protein kinase, putative 0.0039 0.0047 0.1893
Echinococcus multilocularis protein tyrosine kinase 0.0039 0.0047 0.0056
Echinococcus multilocularis tyrosine protein kinase shark 0.0039 0.0047 0.0056
Brugia malayi MAX-1A 0.0042 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0042 0.0058 0.0069
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0042 0.0058 0.3474
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0042 0.0058 0.0376
Brugia malayi regulator of G-protein signaling egl-10 0.0456 0.1544 0.1544
Onchocerca volvulus 0.0042 0.0058 0.0263
Echinococcus multilocularis regulator of G protein signaling 0.0456 0.1544 0.1846
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0064 0.3835
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0042 0.0058 0.0069
Brugia malayi Regulator of G protein signaling domain containing protein 0.0456 0.1544 0.1544
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0039 0.0047 0.1893
Schistosoma mansoni oxysterol-binding protein 1 0.0042 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0167 0.1083
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Giardia lamblia Protein 21.1 0.0039 0.0047 0.2799
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 0.5
Echinococcus granulosus tyrosine protein kinase shark 0.0039 0.0047 0.0056
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0039 0.0047 0.0303
Onchocerca volvulus 0.0039 0.0047 0.0206
Entamoeba histolytica hypothetical protein 0.0456 0.1544 1
Onchocerca volvulus outspread protein homolog 0.0042 0.0058 0.0263
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis Oxysterol binding protein 11 0.0042 0.0058 0.0069
Schistosoma mansoni oxysterol-binding protein 1 0.0042 0.0058 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0043 0.0051
Echinococcus multilocularis beta 1 syntrophin 0.0042 0.0058 0.0069
Echinococcus granulosus cytohesin 1 0.0042 0.0058 0.0069
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.0163 0.0195
Loa Loa (eye worm) hypothetical protein 0.0456 0.1544 0.1544
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Brugia malayi regulator of G-protein signaling rgs-7 0.0456 0.1544 0.1544
Echinococcus granulosus tyrosine protein kinase pr2 0.0039 0.0047 0.0056
Brugia malayi Protein kinase domain containing protein 0.0266 0.0864 0.0864
Loa Loa (eye worm) TK/EPH protein kinase 0.0039 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase csk 0.0039 0.0047 0.0056
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0058 0.3474
Onchocerca volvulus 0.0042 0.0058 0.0263
Toxoplasma gondii Oxysterol-binding protein 0.0042 0.0058 0.235
Echinococcus granulosus epidermal growth factor receptor 0.0039 0.0047 0.0056
Echinococcus granulosus exocyst complex component 2 0.0109 0.0299 0.0357
Leishmania major protein kinase, putative 0.0072 0.0167 1
Brugia malayi plexin A 0.0689 0.2384 0.2384
Echinococcus granulosus fibroblast growth factor receptor 4 0.0039 0.0047 0.0056
Brugia malayi Pleckstrin Homology Domain 0.0042 0.0058 0.0058
Brugia malayi PXA domain containing protein 0.0456 0.1544 0.1544
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica ankyrin repeat protein 0.0039 0.0047 0.0303
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.013 0.0786
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0053 0.0099 0.0643
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0039 0.0047 0.0056
Echinococcus multilocularis epidermal growth factor receptor 0.0039 0.0047 0.0056
Schistosoma mansoni rho gtpase activating protein 0.0042 0.0058 0.0058
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0042 0.0058 0.0069
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.013 0.0786
Echinococcus granulosus kinase suppressor of Ras 1 0.0039 0.0047 0.0056
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0042 0.0058 0.0058
Schistosoma mansoni vav2 0.0042 0.0058 0.0058
Trichomonas vaginalis hypothetical protein 0.0042 0.0058 0.0376
Schistosoma mansoni axis inhibition protein axin 0.0456 0.1544 0.1544
Trypanosoma cruzi Protein kinase B 0.0053 0.0099 0.5935
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0058 0.235
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 1
Echinococcus granulosus protein kinase 0.0039 0.0047 0.0056
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase HCK 0.0039 0.0047 0.0056
Brugia malayi DNA-binding protein LAG-1 0.0109 0.0299 0.0299
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) TK/Met protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni vesicular amine transporter 0.0081 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis Regulator of G protein signaling 20 0.0456 0.1544 0.1846
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus granulosus G protein coupled receptor kinase 1 0.1698 0.6008 0.7183
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0039 0.0047 0.0056
Plasmodium vivax tyrosine kinase-like protein, putative 0.0039 0.0047 0.1893
Schistosoma mansoni ephrin receptor 0.0043 0.0064 0.0064
Leishmania major hypothetical protein, conserved 0.0042 0.0058 0.3474
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis tyrosine protein kinase csk 0.0039 0.0047 0.0056
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Onchocerca volvulus 0.0043 0.0064 0.0293
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0042 0.0058 0.235
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0033 0.1975
Echinococcus multilocularis heat shock protein 70 0.0039 0.0047 0.0056
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) beta-lactamase 0.0043 0.0064 0.0064
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0042 0.0058 0.0058
Echinococcus granulosus tyrosine kinase 0.0039 0.0047 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0183 0.0183
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0042 0.0058 0.3474
Trichomonas vaginalis kinesin light chain, putative 0.0042 0.0058 0.0376
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica ankyrin repeat protein 0.0039 0.0047 0.0303
Schistosoma mansoni hypothetical protein 0.0332 0.1102 0.1102
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.013 0.0156
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0039 0.0047 0.0303
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0058 0.0376
Loa Loa (eye worm) sema domain-containing protein 0.0248 0.08 0.08
Trypanosoma brucei PH domain containing protein, putative 0.0042 0.0058 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Echinococcus granulosus axis inhibition protein axin 0.0456 0.1544 0.1846
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Loa Loa (eye worm) hypothetical protein 0.0248 0.08 0.08
Trichomonas vaginalis esterase, putative 0.0043 0.0064 0.0415
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0183 0.0183
Echinococcus multilocularis regulator of G protein signaling 3 0.0456 0.1544 0.1846
Trypanosoma cruzi PH domain containing protein, putative 0.0042 0.0058 0.3474
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0183 0.0183
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0042 0.0058 0.0376
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus granulosus GRB2 associated binding protein 3 0.0042 0.0058 0.0069
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.0163 0.0195
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0058 0.0376
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0079 0.0191 0.0229
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi Regulator of G protein signaling domain containing protein 0.0456 0.1544 0.1544
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis protein kinase atn1, putative 0.0039 0.0047 0.0303
Schistosoma mansoni dynamin 0.0042 0.0058 0.0058
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis integrin linked protein kinase 0.0039 0.0047 0.0056
Brugia malayi beta-lactamase 0.0043 0.0064 0.0064
Brugia malayi serine/threonine-protein kinase 6 0.0072 0.0167 0.0167
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase, putative 0.0072 0.0167 0.1083
Loa Loa (eye worm) hypothetical protein 0.0248 0.08 0.08
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0039 0.0047 0.0056
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0039 0.0047 0.0047
Trypanosoma cruzi NIMA-related kinase, putative 0.0053 0.0099 0.5935
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0171 0.0171
Brugia malayi Sema domain containing protein 0.0248 0.08 0.08
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0183 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein 0.0456 0.1544 1
Echinococcus multilocularis myotubularin protein 13 0.0042 0.0058 0.0069
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0043 0.0051
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0042 0.0058 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis rac serine:threonine kinase 0.0053 0.0099 0.0119
Plasmodium vivax importin-beta 2, putative 0.0035 0.0033 0.1336
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Schistosoma mansoni serine/threonine-protein kinase 0.0053 0.0099 0.0099
Echinococcus granulosus defective proboscis extension response 0.0079 0.0191 0.0229
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0039 0.0047 0.0056
Echinococcus granulosus importin subunit beta 1 0.0035 0.0033 0.0039
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0042 0.0058 0.235
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0183 0.0183
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0079 0.0191 0.0191
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Brugia malayi Raf kinase 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Echinococcus granulosus receptor type guanylyl cyclase 0.0039 0.0047 0.0056
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0064 0.0076
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis expressed protein 0.0456 0.1544 0.1846
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Echinococcus multilocularis snurportin 1 0.0372 0.1243 0.1486
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus granulosus integrin linked protein kinase 0.0039 0.0047 0.0056
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Echinococcus granulosus Pleckstrin y 0.0042 0.0058 0.0069
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0064
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0042 0.0058 0.0069
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Echinococcus multilocularis transcription factor collier 0.0109 0.0299 0.0357
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0042 0.0058 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.1544 1
Schistosoma mansoni hypothetical protein 0.0372 0.1243 0.1243
Onchocerca volvulus 0.0039 0.0047 0.0206
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0183 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0058 0.0376
Echinococcus multilocularis activated cdc42 kinase 1 0.0039 0.0047 0.0056
Echinococcus granulosus snurportin 1 0.0372 0.1243 0.1486
Plasmodium falciparum protein kinase, putative 0.0039 0.0047 0.1893
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0167 0.1083
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0042 0.0058 0.0263
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0039 0.0047 0.0056
Loa Loa (eye worm) RGS-3 protein 0.0456 0.1544 0.1544
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0033 0.1975
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0042 0.0058 0.0069
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0009 0.0061
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0109 0.0299 0.1935
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0039 0.0047 0.0047
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.0247 0.0295
Echinococcus granulosus MAM 0.0027 0.0006 0.0007
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Entamoeba histolytica tyrosin kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0171 0.0171
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0456 0.1544 0.1544
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Entamoeba histolytica PH domain containing protein 0.0042 0.0058 0.0376
Brugia malayi Cytohesin 3 0.0042 0.0058 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.2154 0.7644 0.7644
Echinococcus granulosus serine/threonine protein kinase 0.0053 0.0099 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0456 0.1544 0.1544
Brugia malayi jmjC domain containing protein 0.0073 0.0171 0.0171
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0006 0.0006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0456 0.1544 0.1846
Schistosoma mansoni nephrin 0.0084 0.0208 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.1544 1
Brugia malayi hypothetical protein 0.0248 0.08 0.08
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.1243 0.1243
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Onchocerca volvulus 0.0581 0.1994 1
Entamoeba histolytica hypothetical protein 0.0042 0.0058 0.0376
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0163 0.0163
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0072 0.0167 0.1083
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Echinococcus multilocularis Rho GTPase activating protein 24 0.0042 0.0058 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0084 0.0208 0.0208
Onchocerca volvulus 0.0042 0.0058 0.0263
Schistosoma mansoni hypothetical protein 0.0039 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0053 0.0099 0.4015
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.1544 1
Trichomonas vaginalis alpha chimerin, putative 0.0042 0.0058 0.0376
Loa Loa (eye worm) hypothetical protein 0.0079 0.0191 0.0191
Brugia malayi hypothetical protein 0.0042 0.0058 0.0058
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0183 0.0218
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Plasmodium falciparum tyrosine kinase-like protein 0.0039 0.0047 0.1893
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0042 0.0058 0.0376
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus twitchin 0.009 0.0233 0.0278
Echinococcus granulosus protein tyrosine kinase 0.0039 0.0047 0.0056
Echinococcus multilocularis axis inhibition protein axin 0.0456 0.1544 0.1846
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.005 0.0088 0.526
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Toxoplasma gondii phosphatidylinositol transfer protein 0.0042 0.0058 0.235
Brugia malayi Oxysterol-binding protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) TK/DDR protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0248 0.08 0.08
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Plasmodium falciparum importin beta, putative 0.0035 0.0033 0.1336
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Brugia malayi beta-lactamase family protein 0.0043 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Plasmodium falciparum PH domain-containing protein, putative 0.0042 0.0058 0.235
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trypanosoma brucei protein kinase, putative 0.0053 0.0099 0.5935
Echinococcus multilocularis tyrosine protein kinase 0.0039 0.0047 0.0056
Echinococcus granulosus tyrosine protein kinase Lyn 0.005 0.0088 0.0105
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0167 0.02
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni goodpasture antigen-binding protein 0.0042 0.0058 0.0058
Onchocerca volvulus Tyrosine kinase homolog 0.0039 0.0047 0.0206
Onchocerca volvulus 0.0042 0.0058 0.0263
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0039 0.0047 0.0056
Echinococcus granulosus beta 1 syntrophin 0.0042 0.0058 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Echinococcus multilocularis oxysterol binding protein 9 0.0042 0.0058 0.0069
Leishmania major importin beta-1 subunit, putative 0.0028 0.0009 0.056
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Echinococcus multilocularis receptor type guanylyl cyclase 0.0039 0.0047 0.0056
Echinococcus granulosus natriuretic peptide receptor 1 0.0039 0.0047 0.0056
Echinococcus multilocularis neuroglian 0.0079 0.0191 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0094 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Leishmania major protein kinase, putative 0.0053 0.0099 0.5935
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Toxoplasma gondii STE kinase 0.0039 0.0047 0.1893
Onchocerca volvulus 0.0039 0.0047 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Brugia malayi Furin-like cysteine rich region family protein 0.0039 0.0047 0.0047
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/ACK protein kinase 0.0039 0.0047 0.0047
Brugia malayi bone morphogenetic protein type 1 receptor 0.0039 0.0047 0.0047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0039 0.0047 0.0056
Echinococcus multilocularis dual specificity testis specific protein kinase 0.005 0.0088 0.0105
Echinococcus multilocularis dynamin 1 0.0042 0.0058 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Brugia malayi Protein kinase domain containing protein 0.0053 0.0099 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Brugia malayi Dynamin 0.0042 0.0058 0.0058
Echinococcus granulosus activated cdc42 kinase 1 0.0039 0.0047 0.0056
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0039 0.0047 0.0303
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis tyrosine protein kinase pr2 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Echinococcus granulosus regulator of G protein signaling 7 0.0456 0.1544 0.1846
Brugia malayi hypothetical protein 0.0456 0.1544 0.1544
Schistosoma mansoni semaphorin 5-related 0.0248 0.08 0.08
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus granulosus Pleckstrin y 0.0042 0.0058 0.0069
Trypanosoma cruzi NIMA-related kinase, putative 0.0053 0.0099 0.5935
Toxoplasma gondii AtPH1 family protein 0.0042 0.0058 0.235
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0099 0.0643
Onchocerca volvulus 0.0248 0.08 0.3995
Brugia malayi SRC-1 0.0039 0.0047 0.0047
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0039 0.0047 0.0047
Echinococcus multilocularis activin receptor type 0.005 0.0088 0.0105
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Schistosoma mansoni cell adhesion molecule 0.0084 0.0208 0.0208
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0039 0.0047 0.0056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Echinococcus granulosus neuroglian 0.0079 0.0191 0.0229
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Schistosoma mansoni myotubularin-related protein 0.0042 0.0058 0.0058
Entamoeba histolytica protein kinase , putative 0.0072 0.0167 0.1083
Toxoplasma gondii protein kinase 0.0039 0.0047 0.1893
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis Pleckstrin y 0.0042 0.0058 0.0069
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0053 0.0099 0.5935
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0039 0.0047 0.0056
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2154 0.7644 0.7644
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Trypanosoma cruzi aurora B kinase, putative 0.0072 0.0167 1
Brugia malayi A-kinase anchor protein 10, precursor 0.0456 0.1544 0.1544
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis centaurin/arf, putative 0.0042 0.0058 0.0376
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0064 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Schistosoma mansoni protein tyrosine kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0064
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0456 0.1544 0.1544
Loa Loa (eye worm) oxysterol binding protein 0.0042 0.0058 0.0058
Brugia malayi SH2 domain containing protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/CSK protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis centaurin gamma, putative 0.0042 0.0058 0.0376
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0064 0.3835
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0039 0.0047 0.0056
Schistosoma mansoni regulator of G protein signaling 0.0456 0.1544 0.1544
Toxoplasma gondii hypothetical protein 0.0033 0.0025 0.1004
Echinococcus multilocularis DCC interacting protein 13 beta 0.0042 0.0058 0.0069
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni serine/threonine RGC 0.0039 0.0047 0.0047
Schistosoma mansoni protein kinase 0.005 0.0088 0.0088
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0042 0.0058 0.0058
Entamoeba histolytica tyrosin kinase, putative 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Trypanosoma brucei protein kinase, putative 0.005 0.0088 0.526
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Echinococcus multilocularis tyrosine protein kinase Srms 0.0039 0.0047 0.0056
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0042 0.0058 0.0263
Brugia malayi probable spectrin beta chain 0.0042 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase csk 0.0039 0.0047 0.0056
Echinococcus granulosus tyrosine protein kinase csk 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0039 0.0047 0.0047
Entamoeba histolytica cysteine surface protein, putative 0.0039 0.0047 0.0303
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0055 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0039 0.0047 0.0206
Loa Loa (eye worm) hypothetical protein 0.02 0.0627 0.0627
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0042 0.0058 0.0058
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0047 0.0303
Leishmania major hypothetical protein, conserved 0.0042 0.0058 0.3474
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0053 0.0099 0.5935
Echinococcus granulosus insulin receptor 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus expressed protein 0.0456 0.1544 0.1846
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.013 0.4744
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0163 0.0195
Loa Loa (eye worm) protein kinase domain-containing protein 0.0039 0.0047 0.0047
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0047 0.0056
Schistosoma mansoni bromodomain containing protein 0.0076 0.0182 0.0182
Trypanosoma cruzi hypothetical protein 0.0042 0.0058 0.3474
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Loa Loa (eye worm) TK/RYK protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi serine/threonine protein kinase 6 0.0072 0.0167 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Echinococcus granulosus transcription factor collier 0.0109 0.0299 0.0357
Echinococcus granulosus activated cdc42 kinase 1 0.0039 0.0047 0.0056
Schistosoma mansoni syntrophin 0.0042 0.0058 0.0058
Echinococcus multilocularis oxysterol binding protein 1 0.0042 0.0058 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0248 0.08 0.08
Echinococcus granulosus tyrosine protein kinase 0.0039 0.0047 0.0056
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0456 0.1544 0.1544
Loa Loa (eye worm) hypothetical protein 0.0079 0.0191 0.0191
Loa Loa (eye worm) Plekhf2 protein 0.0042 0.0058 0.0058
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0053 0.0099 0.5935
Schistosoma mansoni protein kinase 0.0072 0.0167 0.0167
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0047 0.0047
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis cytohesin 1 0.0042 0.0058 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0058 0.0376
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0047 0.0047
Brugia malayi Variant SH3 domain containing protein 0.0042 0.0058 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi C-terminal src kinase protein 1 0.0039 0.0047 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0064 0.2594
Loa Loa (eye worm) TK/ABL protein kinase 0.0039 0.0047 0.0047
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Echinococcus granulosus roundabout 2 0.0084 0.0208 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Loa Loa (eye worm) AUR protein kinase 0.0072 0.0167 0.0167
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.281 1 1
Entamoeba histolytica hypothetical protein 0.0042 0.0058 0.0376
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0042 0.0058 0.0069
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0039 0.0047 0.0047
Plasmodium falciparum protein kinase, putative 0.005 0.0088 0.3558
Brugia malayi RNA, U transporter 1 0.0099 0.0264 0.0264
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis insulin receptor 0.0039 0.0047 0.0056
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0042 0.0058 0.0069
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0109 0.0299 0.1935
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0039 0.0047 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi Plexin repeat family protein 0.0581 0.1994 0.1994
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase Abl 0.0039 0.0047 0.0056
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.005 0.0088 0.526
Loa Loa (eye worm) SRC-1 0.0039 0.0047 0.0047
Echinococcus granulosus Pleckstrin y 0.0042 0.0058 0.0069
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0033 0.0039
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis roundabout 2 0.0084 0.0208 0.0249
Schistosoma mansoni serine/threonine-protein kinase 0.0053 0.0099 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0581 0.1994 0.1994
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis semaphorin 5B 0.0248 0.08 0.0956
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis epidermal growth factor receptor 0.0039 0.0047 0.0056
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0171 0.0205
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0039 0.0047 0.0206
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0053 0.0099 0.5935
Echinococcus multilocularis hypothetical protein 0.0248 0.08 0.0956
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.013 0.0156
Brugia malayi Importin beta-1 subunit 0.0035 0.0033 0.0033
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0028 0.0009 0.0061
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0042 0.0058 0.0069
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0053 0.0099 0.5935
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0039 0.0047 0.0056
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) serine/threonine protein kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) syntrophin-1 0.0042 0.0058 0.0058
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.005 0.0088 0.526
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0456 0.1544 0.1544
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0064 0.0415
Loa Loa (eye worm) hypothetical protein 0.0109 0.0299 0.0299
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0055 0.0055
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein 0.0053 0.0099 0.0643
Brugia malayi Probable exocyst complex component Sec5 0.0109 0.0299 0.0299
Echinococcus multilocularis pleckstrin y domain containing family A 0.0042 0.0058 0.0069
Entamoeba histolytica protein kinase, putative 0.0072 0.0167 0.1083
Echinococcus multilocularis G protein coupled receptor kinase 6 0.2354 0.8364 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0039 0.0047 0.0056
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0109 0.0299 0.1935
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Onchocerca volvulus 0.0032 0.0023 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0039 0.0047 0.0047
Loa Loa (eye worm) uncoordinated protein 104 0.0042 0.0058 0.0058
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Entamoeba histolytica receptor protein kinase, putative 0.0039 0.0047 0.0303
Brugia malayi Fibronectin type III domain containing protein 0.0084 0.0208 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Loa Loa (eye worm) hypothetical protein 0.0079 0.0191 0.0191
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0079 0.0191 0.0191
Schistosoma mansoni hypothetical protein 0.0027 0.0006 0.0006
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0042 0.0058 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0042 0.0058 0.0069
Trichomonas vaginalis STE family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0039 0.0047 0.0056
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0064 0.0064
Plasmodium falciparum calcium-dependent protein kinase 7 0.0053 0.0099 0.4015
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0167 0.1083
Echinococcus granulosus regulator of G protein signaling 3 0.0456 0.1544 0.1846
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0064 0.0415
Plasmodium vivax PH domain containing protein 0.0042 0.0058 0.235
Brugia malayi hypothetical protein 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0006 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0072 0.0167 0.02
Toxoplasma gondii protein kinase domain-containing protein 0.0039 0.0047 0.1893
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0058 0.235
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0047 0.0047
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 1
Echinococcus multilocularis Pleckstrin y 0.0042 0.0058 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Plasmodium falciparum protein kinase, putative 0.0039 0.0047 0.1893
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0064 0.0064
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.2354 0.8364 0.8364
Entamoeba histolytica hypothetical protein 0.0109 0.0299 0.1935
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.0047 0.0303
Echinococcus granulosus tar DNA binding protein 0.0076 0.0183 0.0218
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Brugia malayi hypothetical protein 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0064
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni axis inhibition protein axin 0.0456 0.1544 0.1544
Echinococcus multilocularis raf serine:threonine protein kinase 0.0039 0.0047 0.0056
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0299 0.1935
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0183 0.0183
Brugia malayi ephrin receptor 1 precursor 0.0039 0.0047 0.0047
Entamoeba histolytica serine/threonine kinase, putative 0.0039 0.0047 0.0303
Onchocerca volvulus 0.0043 0.0064 0.0293
Echinococcus multilocularis Immunoglobulin 0.0079 0.0191 0.0229
Toxoplasma gondii aurora kinase 0.0072 0.0167 0.6765
Schistosoma mansoni fibrocystin l 0.0109 0.0299 0.0299
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0039 0.0047 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/FAK protein kinase 0.0039 0.0047 0.0047
Mycobacterium leprae Probable lipase LipE 0.0043 0.0064 0.1768
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0042 0.0058 0.0069
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0064 0.0415
Schistosoma mansoni protein kinase 0.005 0.0088 0.0088
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0039 0.0047 0.0056
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi TBC domain containing protein 0.0042 0.0058 0.0058
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0033 0.1336
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.1544 1
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein 0.0053 0.0099 0.0643
Schistosoma mansoni hypothetical protein 0.0027 0.0006 0.0006
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Brugia malayi Receptor family ligand binding region containing protein 0.0039 0.0047 0.0047
Loa Loa (eye worm) RNA binding protein 0.0076 0.0183 0.0183
Trichomonas vaginalis centaurin/arf, putative 0.0042 0.0058 0.0376
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.2354 0.8364 0.8364
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Echinococcus multilocularis protein kinase 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi integrin-linked kinase 0.0039 0.0047 0.0047
Brugia malayi hypothetical protein 0.0027 0.0006 0.0006
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Toxoplasma gondii hypothetical protein 0.0042 0.0058 0.235
Schistosoma mansoni plexin 0.0581 0.1994 0.1994
Brugia malayi IPT/TIG domain containing protein 0.0109 0.0299 0.0299
Echinococcus granulosus Immunoglobulin 0.0079 0.0191 0.0229
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0053 0.0099 0.5935
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0456 0.1544 0.1544
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0456 0.1544 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0191 0.0191
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Plasmodium falciparum tyrosine kinase-like protein 0.0039 0.0047 0.1893
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0332 0.1102 0.1102
Echinococcus granulosus tyrosine protein kinase csk 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Schistosoma mansoni plexin 0.0332 0.1102 0.1102
Onchocerca volvulus Protein melted homolog 0.0042 0.0058 0.0263
Entamoeba histolytica serine/threonine kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0039 0.0047 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Brugia malayi Immunoglobulin I-set domain containing protein 0.0084 0.0208 0.0208
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0047 0.0056
Brugia malayi Oxysterol binding protein 0.0042 0.0058 0.0058
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0039 0.0047 0.0056
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0053 0.0099 0.4015
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0042 0.0058 0.0069
Loa Loa (eye worm) hypothetical protein 0.0079 0.0191 0.0191
Leishmania major protein kinase, putative 0.0039 0.0047 0.2799
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Schistosoma mansoni ephrin receptor 0.0039 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Echinococcus granulosus pleckstrin y domain containing family A 0.0042 0.0058 0.0069
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0042 0.0058 0.0058
Brugia malayi Uncoordinated protein 104 0.0042 0.0058 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0033 0.0025 0.0025
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0039 0.0047 0.0047
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0118 0.033 0.033
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Echinococcus granulosus dual specificity testis-specific protein kinase 0.005 0.0088 0.0105
Echinococcus granulosus axis inhibition protein axin 0.0456 0.1544 0.1846
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis tyrosine protein kinase csk 0.0039 0.0047 0.0056
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0034 0.0221
Brugia malayi hypothetical protein 0.0456 0.1544 0.1544
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Brugia malayi Syntrophin-1 0.0042 0.0058 0.0058
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0053 0.0099 0.5935
Brugia malayi Bromodomain containing protein 0.0046 0.0074 0.0074
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.0247 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0064 0.0064
Brugia malayi Probable ClpP-like protease 0.0094 0.0247 0.0247
Giardia lamblia Kinase 0.0039 0.0047 0.2799
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0039 0.0047 0.0056
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0025 0.1004
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Schistosoma mansoni importin beta-1 0.0035 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Onchocerca volvulus 0.0042 0.0058 0.0263
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0047
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0064 0.3835
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.2354 0.8364 1
Trypanosoma brucei Pseudokinase, putative 0.0039 0.0047 0.2799
Trypanosoma cruzi protein kinase, putative 0.0039 0.0047 0.2799
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase, putative 0.0053 0.0099 0.0643
Brugia malayi hypothetical protein 0.0039 0.0047 0.0047
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0042 0.0058 0.0058
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0053 0.0099 0.5935
Trichomonas vaginalis protein transport protein sec7, putative 0.0042 0.0058 0.0376
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0099 0.0643
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis pdz domain containing protein 0.0042 0.0058 0.0069
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis protein kinase 0.0039 0.0047 0.0056
Schistosoma mansoni hypothetical protein 0.0109 0.0299 0.0299
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0099 0.0643
Loa Loa (eye worm) cytohesin 3 0.0042 0.0058 0.0058
Brugia malayi Cadps2 protein 0.0042 0.0058 0.0058
Echinococcus multilocularis regulator of G protein signaling 7 0.0456 0.1544 0.1846
Loa Loa (eye worm) AUR protein kinase 0.0072 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0009 0.0061
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus multilocularis regulator of G protein signaling 3 0.0456 0.1544 0.1846
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Schistosoma mansoni z-protein (S1r protein) 0.0456 0.1544 0.1544
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0042 0.0058 0.0058
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0039 0.0047 0.1893
Brugia malayi hypothetical protein 0.0084 0.0208 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Echinococcus granulosus retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Leishmania major hypothetical protein, conserved 0.0043 0.0064 0.3835
Loa Loa (eye worm) hypothetical protein 0.0456 0.1544 0.1544
Schistosoma mansoni goodpasture antigen-binding protein 0.0042 0.0058 0.0058
Echinococcus granulosus tyrosine protein kinase Blk 0.0039 0.0047 0.0056
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica hypothetical protein 0.0456 0.1544 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Entamoeba histolytica PH domain containing protein 0.0042 0.0058 0.0376
Entamoeba histolytica ARF GTPase activating protein, putative 0.0042 0.0058 0.0376
Echinococcus granulosus oxysterol binding protein 9 0.0042 0.0058 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Entamoeba histolytica protein kinase domain containing protein 0.0147 0.0438 0.2834
Loa Loa (eye worm) TK/INSR protein kinase 0.0039 0.0047 0.0047
Schistosoma mansoni regulator of G protein signaling 0.0456 0.1544 0.1544
Echinococcus multilocularis tyrosine protein kinase Blk 0.0039 0.0047 0.0056
Schistosoma mansoni hypothetical protein 0.0042 0.0058 0.0058
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0009 0.056
Echinococcus multilocularis Pleckstrin y 0.0042 0.0058 0.0069
Onchocerca volvulus Putative zinc finger protein 0.0042 0.0058 0.0263
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0043 0.0043
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0042 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0035 0.0033 0.0033
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Toxoplasma gondii hypothetical protein 0.0042 0.0058 0.235
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0039 0.0047 0.0056
Echinococcus multilocularis FL cytokine receptor 0.0039 0.0047 0.0056
Echinococcus granulosus raf serine:threonine protein kinase 0.0039 0.0047 0.0056
Brugia malayi Bromodomain containing protein 0.0091 0.0233 0.0233
Echinococcus granulosus ephrin type A receptor 4 A 0.0039 0.0047 0.0056
Onchocerca volvulus 0.0039 0.0047 0.0206
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0053 0.0099 0.5935
Loa Loa (eye worm) hypothetical protein 0.0042 0.0058 0.0058
Toxoplasma gondii protein kinase domain-containing protein 0.0053 0.0099 0.4015
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Onchocerca volvulus 0.0039 0.0047 0.0206
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0109 0.0299 0.1935
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Schistosoma mansoni dynamin 0.0042 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0039 0.0047 0.0056
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0079 0.0191 0.0229
Echinococcus multilocularis exocyst complex component 2 0.0109 0.0299 0.0357
Echinococcus multilocularis kinase suppressor of Ras 1 0.0039 0.0047 0.0056
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0039 0.0047 0.0303
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0058 0.0376
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Brugia malayi PH domain containing protein 0.0042 0.0058 0.0058
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0039 0.0047 0.0056
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus granulosus retinal guanylyl cyclase 2 0.0039 0.0047 0.0056
Echinococcus granulosus regulator of G protein signaling 7 0.0456 0.1544 0.1846
Echinococcus multilocularis natriuretic peptide receptor 1 0.0039 0.0047 0.0056
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0171 0.0171
Echinococcus multilocularis beta adrenergic receptor kinase 0.2154 0.7644 0.9139
Loa Loa (eye worm) TK/ALK protein kinase 0.0266 0.0864 0.0864
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Schistosoma mansoni protein kinase 0.0039 0.0047 0.0047
Onchocerca volvulus 0.0039 0.0047 0.0206
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0167 0.02
Loa Loa (eye worm) TK protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0456 0.1544 0.1846
Entamoeba histolytica protein kinase, putative 0.0039 0.0047 0.0303
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0064 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0058 0.235
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0047 0.0047
Brugia malayi SH2 domain containing protein 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0039 0.0047 0.0303
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0047 0.0056
Entamoeba histolytica hypothetical protein 0.0042 0.0058 0.0376
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0047 0.0047
Entamoeba histolytica cell surface protease gp63, putative 0.0109 0.0299 0.1935
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0064 0.0415
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus granulosus plexin a4 0.0689 0.2384 0.2851
Echinococcus multilocularis ephrin type A receptor 4 A 0.0039 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0248 0.08 0.08
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0042 0.0058 0.0069
Brugia malayi Plekhf2 protein 0.0042 0.0058 0.0058
Leishmania major protein kinase, putative 0.0053 0.0099 0.5935
Echinococcus multilocularis tyrosine protein kinase csk 0.0039 0.0047 0.0056
Echinococcus multilocularis GRB2 associated binding protein 3 0.0042 0.0058 0.0069
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0042 0.0058 0.0376
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0039 0.0047 0.0047
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0042 0.0058 0.0376
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.0247 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.1544 1
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0039 0.0047 0.0056
Echinococcus granulosus semaphorin 5B 0.0248 0.08 0.0956
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Loa Loa (eye worm) AUR protein kinase 0.0072 0.0167 0.0167
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0042 0.0058 0.235
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0064 0.0077
Echinococcus granulosus pdz domain containing protein 0.0042 0.0058 0.0069
Echinococcus granulosus beta-adrenergic receptor kinase 0.2154 0.7644 0.9139
Entamoeba histolytica tyrosine kinase, putative 0.0039 0.0047 0.0303
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0039 0.0047 0.0303
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0072 0.0167 0.1083
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Loa Loa (eye worm) plexin A 0.0689 0.2384 0.2384
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0109 0.0299 0.0299
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0058 0.0376
Schistosoma mansoni tyrosine kinase 0.0039 0.0047 0.0047
Echinococcus multilocularis regulator of G protein signaling 7 0.0456 0.1544 0.1846
Schistosoma mansoni hypothetical protein 0.0248 0.08 0.08
Trichomonas vaginalis TKL family protein kinase 0.0039 0.0047 0.0303
Trypanosoma brucei aurora B kinase 0.0072 0.0167 1
Brugia malayi Protein kinase domain containing protein 0.0039 0.0047 0.0047
Brugia malayi PHD-finger family protein 0.003 0.0016 0.0016
Schistosoma mansoni zinc finger protein 0.0042 0.0058 0.0058
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0047 0.0303
Echinococcus multilocularis protein KINase family member (kin 25) 0.0039 0.0047 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.1544 1
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0099 0.0643
Loa Loa (eye worm) rho-GTPase-activating 0.0042 0.0058 0.0058

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.4611 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 0.7079 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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