Detailed information for compound 1414678

Basic information

Technical information
  • TDR Targets ID: 1414678
  • Name: 4-methoxy-N-[4-(5-methylfuran-2-yl)phenyl]-3- morpholin-4-ylsulfonylbenzamide
  • MW: 456.511 | Formula: C23H24N2O6S
  • H donors: 1 H acceptors: 3 LogP: 2.63 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)Nc1ccc(cc1)c1ccc(o1)C
  • InChi: 1S/C23H24N2O6S/c1-16-3-9-20(31-16)17-4-7-19(8-5-17)24-23(26)18-6-10-21(29-2)22(15-18)32(27,28)25-11-13-30-14-12-25/h3-10,15H,11-14H2,1-2H3,(H,24,26)
  • InChiKey: LBPCDLCIQRHHJQ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 4-methoxy-N-[4-(5-methyl-2-furyl)phenyl]-3-morpholinosulfonyl-benzamide
  • 4-methoxy-N-[4-(5-methyl-2-furyl)phenyl]-3-morpholinosulfonylbenzamide
  • 4-methoxy-N-[4-(5-methylfuran-2-yl)phenyl]-3-morpholin-4-ylsulfonyl-benzamide
  • ZINC01238049
  • 4-Methoxy-N-[4-(5-methyl-furan-2-yl)-phenyl]-3-(morpholine-4-sulfonyl)-benzamide
  • ASN 05833256
  • SMR000005647
  • MLS000027184

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens Rap guanine nucleotide exchange factor (GEF) 3 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog Get druggable targets OG5_131726 All targets in OG5_131726
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131726 All targets in OG5_131726
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Brugia malayi N-terminal motif family protein Get druggable targets OG5_131726 All targets in OG5_131726
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0077 0.0091
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0051 0.0093 0.0111
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0051 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0056 0.0107 0.0107
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0076 0.4723
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis TK family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0056 0.0107 0.0128
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0037 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0075 0.0156 0.0982
Schistosoma mansoni protein kinase 0.0067 0.0135 0.0135
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0056 0.0107 0.6645
Echinococcus granulosus MAM 0.0028 0.0034 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0004 0.0004
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0093 0.0588
Schistosoma mansoni protein kinase 0.0067 0.0135 0.0135
Onchocerca volvulus 0.0056 0.0107 0.0519
Echinococcus granulosus beta-adrenergic receptor kinase 0.2903 0.7656 0.9144
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0067 0.0135 0.836
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0009 0.001
Brugia malayi CXXC zinc finger family protein 0.0035 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0098 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0148 0.0351 0.0351
Echinococcus granulosus fibroblast growth factor receptor 4 0.0051 0.0093 0.0111
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0032 0.0043 0.0043
Trypanosoma cruzi PH domain containing protein, putative 0.0056 0.0107 0.6645
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0056 0.0107 0.0128
Trichomonas vaginalis centaurin gamma, putative 0.0056 0.0107 0.0677
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0056 0.0107 0.0128
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Entamoeba histolytica hypothetical protein 0.0148 0.0351 0.2212
Entamoeba histolytica hypothetical protein 0.0043 0.0073 0.0462
Schistosoma mansoni peptidase 0.0019 0.001 0.001
Brugia malayi ephrin receptor 1 precursor 0.0051 0.0093 0.0093
Schistosoma mansoni lamin 0.0033 0.0044 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0614 0.1586 1
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0056 0.0107 0.0128
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0051 0.0093 0.0111
Entamoeba histolytica hypothetical protein 0.0148 0.0351 0.2212
Echinococcus multilocularis calcium dependent secretion activator 1 0.0056 0.0107 0.0128
Schistosoma mansoni ephrin receptor 0.0056 0.0106 0.0106
Echinococcus multilocularis tyrosine protein kinase HCK 0.0051 0.0093 0.0111
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.003 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0153 0.9433
Onchocerca volvulus 0.0796 0.2068 1
Echinococcus granulosus natriuretic peptide receptor 1 0.0051 0.0093 0.0111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0153 1
Echinococcus granulosus tyrosine protein kinase 0.0051 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0148 0.0351 0.0351
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0056 0.0107 0.0677
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0148 0.0351 0.2212
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.005 0.005
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Schistosoma mansoni hypothetical protein 0.0056 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0614 0.1586 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0118 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0009 0.001
Leishmania major protein kinase, putative 0.0026 0.0026 0.1633
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi hypothetical protein 0.0051 0.0093 0.0093
Echinococcus granulosus dynamin 1 0.0056 0.0107 0.0128
Trichomonas vaginalis STE family protein kinase 0.0051 0.0093 0.0588
Mycobacterium tuberculosis Probable lipase LipD 0.003 0.0037 0.0799
Brugia malayi TBC domain containing protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0072 0.0149 0.0942
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0072 0.0149 0.9237
Echinococcus granulosus regulator of G protein signaling 3 0.0614 0.1586 0.1894
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0153 0.0153
Schistosoma mansoni cpg binding protein 0.0035 0.005 0.005
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus granulosus oxysterol binding protein 1 0.0056 0.0107 0.0128
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis axis inhibition protein axin 0.0614 0.1586 0.1894
Entamoeba histolytica p21-activated kinase 0.0072 0.0149 0.0942
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0051 0.0093 0.0451
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0051 0.0093 0.0111
Schistosoma mansoni hypothetical protein 0.0338 0.0855 0.0855
Echinococcus multilocularis oxysterol binding protein 9 0.0056 0.0107 0.0128
Brugia malayi N-terminal motif family protein 0.0223 0.055 0.055
Entamoeba histolytica protein kinase, putative 0.0075 0.0156 0.0982
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis regulator of G protein signaling 3 0.0614 0.1586 0.1894
Echinococcus granulosus lamin dm0 0.0033 0.0044 0.0053
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0056 0.0107 0.0677
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0051 0.0093 0.0111
Echinococcus multilocularis geminin 0.0205 0.0501 0.0598
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Echinococcus multilocularis regulator of G protein signaling 7 0.0625 0.1614 0.1928
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0153 0.3304
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0077 0.0162 1
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Schistosoma mansoni hypothetical protein 0.0056 0.0107 0.0107
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0001 0.0001
Echinococcus multilocularis beta 1 syntrophin 0.0056 0.0107 0.0128
Schistosoma mansoni dynamin 0.0056 0.0107 0.0107
Entamoeba histolytica PH domain containing protein 0.0056 0.0107 0.0677
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0037 0.2282
Leishmania major serine/threonine-protein kinase a, putative 0.0072 0.0149 0.9237
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0077 0.4732
Onchocerca volvulus 0.0033 0.0044 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Plasmodium falciparum PH domain-containing protein, putative 0.0056 0.0107 0.6899
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Brugia malayi hypothetical protein 0.0028 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0056 0.0107 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0026 0.0026
Brugia malayi Tyrosine-protein kinase PR2 0.0051 0.0093 0.0093
Echinococcus multilocularis FL cytokine receptor 0.0051 0.0093 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Plasmodium vivax hypothetical protein, conserved 0.0056 0.0107 0.6899
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0009 0.0009
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0051 0.0093 0.0093
Echinococcus granulosus neuroglian 0.0098 0.0217 0.0259
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0142 0.9296
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0072 0.0149 0.9237
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0056 0.0107 0.6899
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Mycobacterium leprae Probable lipase LipE 0.003 0.0037 0.5769
Loa Loa (eye worm) TK/ACK protein kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0056 0.0107 0.0128
Echinococcus granulosus roundabout 2 0.0103 0.023 0.0275
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0077 0.0077
Schistosoma mansoni regulator of G protein signaling 0.0625 0.1614 0.1614
Loa Loa (eye worm) hypothetical protein 0.0045 0.0077 0.0077
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0077 0.0162 1
Brugia malayi hypothetical protein 0.0338 0.0855 0.0855
Loa Loa (eye worm) TK/DDR protein kinase 0.0051 0.0093 0.0093
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Echinococcus multilocularis titin 0.0021 0.0013 0.0015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0051 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni myotubularin-related protein 0.0056 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica hypothetical protein 0.0043 0.0073 0.0462
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0051 0.0093 0.0093
Schistosoma mansoni goodpasture antigen-binding protein 0.0056 0.0107 0.0107
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Entamoeba histolytica ankyrin repeat protein 0.0051 0.0093 0.0588
Echinococcus granulosus c src tyrosine kinase 0.0051 0.0093 0.0111
Onchocerca volvulus 0.0051 0.0093 0.0451
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Schistosoma mansoni hypothetical protein 0.0051 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Brugia malayi C-terminal src kinase protein 1 0.0051 0.0093 0.0093
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0156 0.0156
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0072 0.0149 0.9237
Echinococcus granulosus transcription factor collier 0.0148 0.0351 0.0419
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0056 0.0107 0.0677
Echinococcus granulosus tyrosine protein kinase Src64B 0.0051 0.0093 0.0111
Brugia malayi DNA-binding protein LAG-1 0.0148 0.0351 0.0351
Leishmania major protein kinase, putative 0.0072 0.0149 0.9237
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Onchocerca volvulus 0.0051 0.0093 0.0451
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Schistosoma mansoni intermediate filament proteins 0.0033 0.0044 0.0044
Schistosoma mansoni regulator of G protein signaling 0.0614 0.1586 0.1586
Echinococcus multilocularis actin binding protein anillin 0.0056 0.0107 0.0128
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0075 0.0156 1
Echinococcus multilocularis transcription factor collier 0.0148 0.0351 0.0419
Plasmodium falciparum cGMP-dependent protein kinase 0.0026 0.0026 0.1696
Echinococcus granulosus geminin 0.0205 0.0501 0.0598
Onchocerca volvulus 0.0035 0.005 0.0242
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.0093 0.0588
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0037 0.2282
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Echinococcus granulosus exocyst complex component 2 0.0148 0.0351 0.0419
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni tyrosine protein kinase 0.0051 0.0093 0.0093
Brugia malayi Regulator of G protein signaling domain containing protein 0.0614 0.1586 0.1586
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.1439 0.1719
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0142 0.0169
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0009 0.0009
Schistosoma mansoni centaurin alpha 0.0056 0.0107 0.0107
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0051 0.0093 0.0451
Brugia malayi SRC-1 0.0051 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0073 0.0088
Loa Loa (eye worm) hypothetical protein 0.0338 0.0855 0.0855
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0093 0.0111
Entamoeba histolytica hypothetical protein 0.0056 0.0107 0.0677
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0142 0.3071
Leishmania major protein kinase, putative 0.0075 0.0156 0.9631
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0153 0.0153
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0156 0.0156
Echinococcus granulosus ephrin type A receptor 4 A 0.0051 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0458 0.1172 0.1172
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0118 0.0118
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Echinococcus granulosus oxysterol binding protein 9 0.0056 0.0107 0.0128
Echinococcus multilocularis roundabout 2 0.0103 0.023 0.0275
Loa Loa (eye worm) TK/EPH protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0614 0.1586 1
Entamoeba histolytica cell surface protease gp63, putative 0.0148 0.0351 0.2212
Echinococcus granulosus GRB2 associated binding protein 3 0.0056 0.0107 0.0128
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0051 0.0093 0.0111
Onchocerca volvulus Protein melted homolog 0.0056 0.0107 0.0519
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0093 0.0111
Echinococcus granulosus Rho GTPase activating protein 24 0.0056 0.0107 0.0128
Onchocerca volvulus 0.0051 0.0093 0.0451
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0156 0.0982
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0021 0.0013 0.0013
Trichomonas vaginalis kinesin light chain, putative 0.0056 0.0107 0.0677
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0098 0.0217 0.0259
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0056 0.0107 0.0128
Trichomonas vaginalis protein transport protein sec7, putative 0.0056 0.0107 0.0677
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0051 0.0093 0.0588
Chlamydia trachomatis serine/threonine protein kinase 0.0016 0 0.5
Brugia malayi Dynamin 0.0056 0.0107 0.0107
Onchocerca volvulus 0.0051 0.0093 0.0451
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Brugia malayi hypothetical protein 0.0338 0.0855 0.0855
Echinococcus granulosus defective proboscis extension response 0.0098 0.0217 0.0259
Schistosoma mansoni hypothetical protein 0.0056 0.0107 0.0107
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0056 0.0107 0.6899
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Echinococcus granulosus tyrosine kinase 0.0051 0.0093 0.0111
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0051 0.0093 0.5768
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.0075 0.0156 0.0982
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) cytohesin 3 0.0056 0.0107 0.0107
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.0093 0.0111
Echinococcus multilocularis G protein coupled receptor kinase 6 0.3173 0.8372 1
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0044 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Onchocerca volvulus 0.0051 0.0093 0.0451
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0067
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0149 0.0942
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0056 0.0107 0.6899
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Echinococcus multilocularis Ras associated and pleckstrin y 0.0056 0.0107 0.0128
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Brugia malayi Fibronectin type III domain containing protein 0.0103 0.023 0.023
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica hypothetical protein 0.0614 0.1586 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Echinococcus granulosus semaphorin 1A 0.0338 0.0855 0.1021
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica hypothetical protein, conserved 0.0056 0.0107 0.0677
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0056 0.0107 0.6899
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.0093 0.0111
Echinococcus granulosus Regulator of G protein signaling 20 0.0614 0.1586 0.1894
Trypanosoma brucei protein kinase, putative 0.0077 0.0162 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0051 0.0093 0.0093
Trypanosoma brucei Pseudokinase, putative 0.0051 0.0093 0.5768
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica hypothetical protein 0.0614 0.1586 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.3173 0.8372 0.8372
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0162 0.102
Loa Loa (eye worm) hypothetical protein 0.0625 0.1614 0.1614
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0075 0.0156 0.0982
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Onchocerca volvulus 0.0051 0.0093 0.0451
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0072 0.0149 0.9591
Schistosoma mansoni axis inhibition protein axin 0.0614 0.1586 0.1586
Onchocerca volvulus 0.0056 0.0107 0.0519
Brugia malayi Syntrophin-1 0.0056 0.0107 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0156 0.0156
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0067 0.0135 0.0161
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0051 0.0093 0.0111
Echinococcus granulosus beta LACTamase domain containing family member 0.003 0.0037 0.0044
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0056 0.0107 0.0128
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0044 0.0076 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Onchocerca volvulus 0.0051 0.0093 0.0451
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0051 0.0093 0.0111
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0001 0.0001
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0051 0.0093 0.0111
Echinococcus granulosus DCC interacting protein 13 beta 0.0056 0.0107 0.0128
Brugia malayi MAX-1A 0.0056 0.0107 0.0107
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0056 0.0107 0.0128
Loa Loa (eye worm) TK/RYK protein kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis kinase suppressor of Ras 1 0.0051 0.0093 0.0111
Echinococcus granulosus pdz domain containing protein 0.0056 0.0107 0.0128
Trypanosoma cruzi PH domain containing protein, putative 0.0056 0.0107 0.6645
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2903 0.7656 0.7656
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0044 0.0044
Schistosoma mansoni rho gtpase activating protein 0.0056 0.0107 0.0107
Echinococcus multilocularis lamin dm0 0.0033 0.0044 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0614 0.1586 1
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0056 0.0107 0.0519
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Echinococcus granulosus regulator of G protein signaling 3 0.0614 0.1586 0.1894
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0132 0.8183
Loa Loa (eye worm) TK/ALK protein kinase 0.0289 0.0723 0.0723
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0076 0.0091
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis regulator of G protein signaling 7 0.0625 0.1614 0.1928
Entamoeba histolytica hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0051 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0093 0.0588
Toxoplasma gondii AtPH1 family protein 0.0056 0.0107 0.6645
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0051 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0093 0.0111
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0077 0.4732
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3173 0.8372 0.8372
Echinococcus multilocularis cytohesin 1 0.0056 0.0107 0.0128
Schistosoma mansoni zinc finger protein 0.0056 0.0107 0.0107
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.3173 0.8372 1
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0056 0.0107 0.0107
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0056 0.0107 0.0677
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0001 0.0001
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0135 0.0852
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0013 0.0013
Onchocerca volvulus 0.003 0.0037 0.0178
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0009 0.0009
Trypanosoma brucei protein kinase, putative 0.0067 0.0135 0.836
Trichomonas vaginalis conserved hypothetical protein 0.0614 0.1586 1
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.2168 0.2589
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0051 0.0093 0.0588
Schistosoma mansoni serine/threonine-protein kinase 0.0072 0.0149 0.0149
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0026 0.0032
Echinococcus multilocularis Oxysterol binding protein 11 0.0056 0.0107 0.0128
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus granulosus axis inhibition protein axin 0.0614 0.1586 0.1894
Schistosoma mansoni hypothetical protein 0.0338 0.0855 0.0855
Mycobacterium ulcerans esterase/lipase LipP 0.003 0.0037 0.242
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Brugia malayi Cytohesin 3 0.0056 0.0107 0.0107
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Onchocerca volvulus 0.0051 0.0093 0.0451
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0614 0.1586 0.1586
Entamoeba histolytica cysteine surface protein, putative 0.0051 0.0093 0.0588
Brugia malayi regulator of G-protein signaling egl-10 0.0625 0.1614 0.1614
Echinococcus multilocularis beta LACTamase domain containing family member 0.003 0.0037 0.0044
Echinococcus granulosus calcium activated potassium channel 0.0018 0.0007 0.0008
Onchocerca volvulus 0.0051 0.0093 0.0451
Echinococcus multilocularis mitogen activated protein kinase 3 0.0077 0.0162 0.0193
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0051 0.0093 0.0111
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi plexin A 0.0944 0.2461 0.2461
Brugia malayi integrin-linked kinase 0.0051 0.0093 0.0093
Toxoplasma gondii phosphatidylinositol transfer protein 0.0056 0.0107 0.6645
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0051 0.0093 0.0111
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.1439 0.1719
Schistosoma mansoni titin 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi MAP kinase sur-1 0.0077 0.0162 0.0162
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0076 0.4723
Onchocerca volvulus 0.0033 0.0046 0.0225
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0148 0.0351 0.2212
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0026 0.0026 0.1633
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0077 0.0091
Echinococcus granulosus Pleckstrin y 0.0056 0.0107 0.0128
Trichomonas vaginalis esterase, putative 0.003 0.0037 0.0233
Echinococcus multilocularis myotubularin protein 13 0.0056 0.0107 0.0128
Echinococcus multilocularis Rho GTPase activating protein 24 0.0056 0.0107 0.0128
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0051 0.0093 0.0111
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0614 0.1586 0.1586
Schistosoma mansoni hypothetical protein 0.0041 0.0067 0.0067
Echinococcus granulosus neuropeptide s receptor 0.0558 0.1439 0.1719
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0148 0.0351 0.2212
Mycobacterium ulcerans beta-lactamase 0.003 0.0037 0.242
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0098 0.0217 0.0217
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Schistosoma mansoni hypothetical protein 0.0043 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0209 0.0513 0.0513
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus multilocularis Regulator of G protein signaling 20 0.0614 0.1586 0.1894
Brugia malayi regulator of G-protein signaling rgs-7 0.0614 0.1586 0.1586
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0051 0.0093 0.0111
Echinococcus multilocularis tyrosine protein kinase Blk 0.0051 0.0093 0.0111
Echinococcus granulosus cpg binding protein 0.0037 0.0055 0.0066
Echinococcus multilocularis regulator of G protein signaling 0.0614 0.1586 0.1894
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0076 0.0481
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Echinococcus multilocularis beta adrenergic receptor kinase 0.2903 0.7656 0.9144
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0056 0.0107 0.0128
Echinococcus granulosus kinase suppressor of Ras 1 0.0051 0.0093 0.0111
Onchocerca volvulus 0.0338 0.0855 0.4131
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.0093 0.0111
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Brugia malayi protein unc-22 0.0021 0.0013 0.0013
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0077 0.0091
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0019 0.001 0.0599
Brugia malayi Receptor family ligand binding region containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis heat shock protein 70 0.0051 0.0093 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0156 0.0982
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis lamin 0.0033 0.0044 0.0053
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0148 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0098 0.0217 0.0217
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0051 0.0093 0.0111
Giardia lamblia Kinase, NEK 0.0051 0.0093 0.5768
Echinococcus granulosus G protein coupled receptor kinase 1 0.2289 0.6028 0.72
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0026 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Onchocerca volvulus 0.0028 0.0034 0.0162
Loa Loa (eye worm) PH domain-containing protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Mycobacterium leprae conserved hypothetical protein 0.003 0.0037 0.5769
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0077 0.0482
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni dynamin 0.0056 0.0107 0.0107
Echinococcus multilocularis regulator of G protein signaling 3 0.0614 0.1586 0.1894
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0077 0.0091
Echinococcus multilocularis DCC interacting protein 13 beta 0.0056 0.0107 0.0128
Echinococcus granulosus titin 0.0021 0.0013 0.0015
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0056 0.0107 0.0107
Plasmodium falciparum serine/threonine protein kinase, putative 0.0075 0.0156 1
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Srms 0.0051 0.0093 0.0111
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Brugia malayi Variant SH3 domain containing protein 0.0056 0.0107 0.0107
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0009 0.001
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0148 0.0351 0.2212
Echinococcus granulosus expressed protein 0.0614 0.1586 0.1894
Entamoeba histolytica hypothetical protein 0.0614 0.1586 1
Schistosoma mansoni cell adhesion molecule 0.0103 0.023 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Giardia lamblia Kinase, NEK 0.0051 0.0093 0.5768
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0037 0.2282
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0075 0.0156 0.0982
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0077 0.0482
Loa Loa (eye worm) serine/threonine protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus multilocularis hypothetical protein 0.0338 0.0855 0.1021
Echinococcus multilocularis Pleckstrin y 0.0056 0.0107 0.0128
Entamoeba histolytica hypothetical protein 0.0056 0.0107 0.0677
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0093 0.0093
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0118 0.0118
Trypanosoma cruzi protein kinase, putative 0.0051 0.0093 0.5768
Brugia malayi probable spectrin beta chain 0.0056 0.0107 0.0107
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.003 0.0037 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.3787 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni inositol monophosphatase 0.0045 0.0076 0.0076
Echinococcus granulosus activated cdc42 kinase 1 0.0051 0.0093 0.0111
Brugia malayi Variant SH3 domain containing protein 0.0056 0.0107 0.0107
Brugia malayi bone morphogenetic protein type 1 receptor 0.0051 0.0093 0.0093
Brugia malayi Raf kinase 0.0051 0.0093 0.0093
Schistosoma mansoni z-protein (S1r protein) 0.0625 0.1614 0.1614
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.003 0.0037 0.0799
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0077 0.4732
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0051 0.0093 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni lamin 0.0033 0.0044 0.0044
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0051 0.0093 0.0111
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Trypanosoma cruzi Protein kinase B 0.0072 0.0149 0.9237
Loa Loa (eye worm) rho-GTPase-activating 0.0056 0.0107 0.0107
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0072 0.0149 0.9237
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0075 0.0156 0.0186
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Schistosoma mansoni inositol monophosphatase 0.0045 0.0076 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0086 0.0086
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0077 0.0162 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0056 0.0107 0.0128
Toxoplasma gondii protein kinase domain-containing protein 0.0051 0.0093 0.5768
Brugia malayi IPT/TIG domain containing protein 0.0148 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Onchocerca volvulus 0.0051 0.0093 0.0451
Echinococcus granulosus integrin linked protein kinase 0.0051 0.0093 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0614 0.1586 1
Trypanosoma brucei aurora B kinase 0.0075 0.0156 0.9631
Echinococcus granulosus tyrosine kinase 0.0051 0.0093 0.0111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0153 1
Brugia malayi PXA domain containing protein 0.0614 0.1586 0.1586
Loa Loa (eye worm) hypothetical protein 0.0614 0.1586 0.1586
Onchocerca volvulus 0.0051 0.0093 0.0451
Echinococcus multilocularis semaphorin 5B 0.0338 0.0855 0.1021
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0021 0.0013 0.0013
Echinococcus multilocularis aurora kinase A 0.0075 0.0156 0.0186
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0129 0.0129
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni hypothetical protein 0.0148 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Echinococcus multilocularis rac serine:threonine kinase 0.0072 0.0149 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Trypanosoma cruzi aurora B kinase, putative 0.0075 0.0156 0.9631
Brugia malayi Regulator of G protein signaling domain containing protein 0.0614 0.1586 0.1586
Plasmodium vivax hypothetical protein, conserved 0.003 0.0037 0.237
Loa Loa (eye worm) hypothetical protein 0.0098 0.0217 0.0217
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0056 0.0107 0.0677
Echinococcus multilocularis axis inhibition protein axin 0.0614 0.1586 0.1894
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0103 0.023 0.023
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus granulosus plexin a4 0.0944 0.2461 0.294
Giardia lamblia Aurora kinase 0.0075 0.0156 0.9631
Echinococcus multilocularis G protein coupled receptor kinase 1 0.2289 0.6028 0.72
Trichomonas vaginalis alpha chimerin, putative 0.0056 0.0107 0.0677
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) AGC/PKG protein kinase 0.0026 0.0026 0.0026
Echinococcus multilocularis protein tyrosine kinase 0.0051 0.0093 0.0111
Echinococcus granulosus receptor type guanylyl cyclase 0.0051 0.0093 0.0111
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Toxoplasma gondii ABC1 family protein 0.003 0.0037 0.2282
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3787 1 1
Brugia malayi hypothetical protein 0.0051 0.0093 0.0093
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0056 0.0107 0.0677
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Onchocerca volvulus 0.0051 0.0093 0.0451
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0072 0.0149 0.9237
Plasmodium falciparum protein kinase, putative 0.0051 0.0093 0.5989
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0051 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0013 0.0013
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0076 0.5
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Giardia lamblia Kinase 0.0051 0.0093 0.5768
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni hypothetical protein 0.0205 0.0501 0.0501
Trypanosoma brucei rac serine-threonine kinase, putative 0.0072 0.0149 0.9237
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0001 0.0001
Echinococcus granulosus protein kinase 0.0051 0.0093 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Echinococcus granulosus myotubularin protein 13 0.0056 0.0107 0.0128
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0056 0.0107 0.0677
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis protein tyrosine kinase, putative 0.0051 0.0093 0.0588
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.0093 0.0111
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0072 0.0149 0.9237
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Brugia malayi Furin-like cysteine rich region family protein 0.0051 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase pr2 0.0051 0.0093 0.0111
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Mycobacterium tuberculosis Conserved protein 0.003 0.0037 0.0799
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis cpg binding protein 0.0037 0.0055 0.0066
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Chlamydia trachomatis serine/threonine-protein kinase 0.0016 0 0.5
Mycobacterium ulcerans hypothetical protein 0.003 0.0037 0.242
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0614 0.1586 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0077 0.0077
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Onchocerca volvulus Putative zinc finger protein 0.0056 0.0107 0.0519
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Onchocerca volvulus 0.0056 0.0107 0.0519
Echinococcus multilocularis protein KINase family member (kin 25) 0.0051 0.0093 0.0111
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0069 0.0436
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Toxoplasma gondii Oxysterol-binding protein 0.0056 0.0107 0.6645
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0077 0.0482
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Schistosoma mansoni hypothetical protein 0.0494 0.1268 0.1268
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.1268 0.1514
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0056 0.0107 0.0128
Echinococcus granulosus lamin 0.0033 0.0044 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.0093 0.0111
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0072 0.0149 0.9237
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Echinococcus granulosus intermediate filament protein 0.0033 0.0044 0.0053
Schistosoma mansoni cpg binding protein 0.0037 0.0055 0.0055
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0051 0.0093 0.0111
Echinococcus multilocularis natriuretic peptide receptor 1 0.0051 0.0093 0.0111
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni oxysterol-binding protein 1 0.0056 0.0107 0.0107
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0064 1
Brugia malayi Dynamin 0.0056 0.0107 0.0107
Schistosoma mansoni vav2 0.0056 0.0107 0.0107
Schistosoma mansoni hypothetical protein 0.0148 0.0351 0.0351
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0142 0.0142
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0051 0.0093 0.0093
Brugia malayi hypothetical protein 0.0614 0.1586 0.1586
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Onchocerca volvulus 0.0056 0.0107 0.0519
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0067 0.0135 0.836
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0072 0.0149 0.9237
Echinococcus multilocularis tyrosine protein kinase Srms 0.0051 0.0093 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Plasmodium falciparum tyrosine kinase-like protein 0.0051 0.0093 0.5989
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0162 0.102
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0338 0.0855 0.0855
Onchocerca volvulus 0.003 0.0037 0.0178
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0162 0.102
Onchocerca volvulus 0.0056 0.0107 0.0519
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0077 0.0091
Onchocerca volvulus 0.0051 0.0093 0.0451
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0153 1
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0086 0.0086
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis plexin a4 0.0944 0.2461 0.294
Trichomonas vaginalis protein kinase atn1, putative 0.0051 0.0093 0.0588
Echinococcus multilocularis Pleckstrin y 0.0056 0.0107 0.0128
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0077 0.4732
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Trypanosoma cruzi NIMA-related kinase, putative 0.0072 0.0149 0.9237
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus granulosus tyrosine protein kinase HCK 0.0051 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0614 0.1586 0.1894
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Echinococcus multilocularis pdz domain containing protein 0.0056 0.0107 0.0128
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Brugia malayi serine/threonine kinase 12 0.0075 0.0156 0.0156
Trypanosoma cruzi NIMA-related kinase, putative 0.0072 0.0149 0.9237
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0076 0.4723
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Leishmania major folate/biopterin transporter, putative 0.0072 0.0149 0.9237
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0026 0.0026
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0009 0.001
Schistosoma mansoni regulator of G protein signaling 0.0614 0.1586 0.1586
Echinococcus granulosus Pleckstrin y 0.0056 0.0107 0.0128
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) beta-lactamase 0.003 0.0037 0.0037
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) protein kinase domain-containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis raf serine:threonine protein kinase 0.0051 0.0093 0.0111
Schistosoma mansoni regulator of G protein signaling 0.0614 0.1586 0.1586
Entamoeba histolytica hypothetical protein 0.0043 0.0073 0.0462
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.0007 0.0008
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Brugia malayi Plekhf2 protein 0.0056 0.0107 0.0107
Echinococcus multilocularis tyrosine protein kinase pr2 0.0051 0.0093 0.0111
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0026 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0156 0.0982
Entamoeba histolytica hypothetical protein 0.0072 0.0149 0.0942
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Mycobacterium tuberculosis Possible penicillin-binding protein 0.019 0.0462 1
Brugia malayi PXA domain containing protein 0.0614 0.1586 0.1586
Brugia malayi SH2 domain containing protein 0.0051 0.0093 0.0093
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0076 0.4723
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Brugia malayi Egg laying defective protein 4 0.0026 0.0026 0.0026
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0072 0.0149 0.9237
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Echinococcus granulosus axis inhibition protein axin 0.0614 0.1586 0.1894
Echinococcus granulosus twitchin 0.0114 0.0259 0.0309
Echinococcus granulosus pleckstrin y domain containing family A 0.0056 0.0107 0.0128
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0098 0.0217 0.0259
Echinococcus granulosus titin 0.0021 0.0013 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Leishmania major protein kinase, putative 0.0067 0.0135 0.836
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0056 0.0107 0.0107
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0153 0.0182
Brugia malayi Oxysterol binding protein 0.0056 0.0107 0.0107
Toxoplasma gondii hypothetical protein 0.0056 0.0107 0.6645
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0056 0.0107 0.0128
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0051 0.0093 0.0111
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0149 0.0942
Echinococcus multilocularis transfer RNA-Thr 0.0051 0.0093 0.0111
Chlamydia trachomatis serine/threonine protein kinase 0.0016 0 0.5
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.0093 0.0111
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Echinococcus multilocularis integrin linked protein kinase 0.0051 0.0093 0.0111
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0077 0.0162 0.0162
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0153 0.0153
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0077 0.0162 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0051 0.0093 0.0111
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0076 0.0091
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0056 0.0107 0.0128
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0142 0.0142
Echinococcus multilocularis Pleckstrin y 0.0056 0.0107 0.0128
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0223 0.055 0.055
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus granulosus regulator of G protein signaling 7 0.0625 0.1614 0.1928
Echinococcus multilocularis MAM 0.0028 0.0034 0.004
Echinococcus granulosus Pleckstrin y 0.0056 0.0107 0.0128
Brugia malayi Immunoglobulin I-set domain containing protein 0.0103 0.023 0.023
Echinococcus granulosus protein tyrosine kinase 0.0051 0.0093 0.0111
Brugia malayi hypothetical protein 0.0103 0.023 0.023
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Leishmania major hypothetical protein, conserved 0.0051 0.0093 0.5768
Entamoeba histolytica hypothetical protein 0.0043 0.0073 0.0462
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0056 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0051 0.0093 0.0111
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.0486 0.3064
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0142 0.8769
Schistosoma mansoni ephrin receptor 0.0051 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0051 0.0093 0.0111
Schistosoma mansoni semaphorin 5-related 0.0338 0.0855 0.0855
Brugia malayi Uncoordinated protein 104 0.0056 0.0107 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0093 0.0093
Brugia malayi Cadps2 protein 0.0056 0.0107 0.0107
Brugia malayi hypothetical protein 0.0056 0.0107 0.0107
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0067 0.0067
Echinococcus multilocularis activin receptor type 0.0067 0.0135 0.0161
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0051 0.0093 0.0093
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0051 0.0093 0.0093
Onchocerca volvulus 0.0056 0.0107 0.0519
Echinococcus granulosus mitogen activated protein kinase 3 0.0077 0.0162 0.0193
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0338 0.0855 0.0855
Trichomonas vaginalis centaurin/arf, putative 0.0056 0.0107 0.0677
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Brugia malayi serine/threonine protein kinase 6 0.0075 0.0156 0.0156
Echinococcus multilocularis oxysterol binding protein 1 0.0056 0.0107 0.0128
Loa Loa (eye worm) uncoordinated protein 104 0.0056 0.0107 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Onchocerca volvulus 0.0051 0.0093 0.0451
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0037 0.0233
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Brugia malayi Probable exocyst complex component Sec5 0.0148 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0077 0.0162 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0149 0.0942
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) oxysterol binding protein 0.0056 0.0107 0.0107
Brugia malayi SH2 domain containing protein 0.0051 0.0093 0.0093
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0072 0.0149 0.9237
Brugia malayi hypothetical protein 0.0051 0.0093 0.0093
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0077 0.0162 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0093 0.0111
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Echinococcus granulosus serine/threonine protein kinase 0.0072 0.0149 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Entamoeba histolytica receptor protein kinase, putative 0.0051 0.0093 0.0588
Onchocerca volvulus 0.0056 0.0107 0.0519
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0076 0.0481
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0056 0.0107 0.0677
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0067 0.0135 0.836
Loa Loa (eye worm) TK/ROR protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0073 0.0073
Plasmodium falciparum tyrosine kinase-like protein 0.0051 0.0093 0.5989
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0051 0.0093 0.5768
Echinococcus multilocularis tyrosine protein kinase Abl 0.0051 0.0093 0.0111
Echinococcus granulosus microtubule associated protein 2 0.0833 0.2168 0.2589
Echinococcus multilocularis Immunoglobulin 0.0098 0.0217 0.0259
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0056 0.0107 0.0107
Echinococcus multilocularis tyrosine protein kinase shark 0.0051 0.0093 0.0111
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0153 0.9433
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0093 0.0111
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0051 0.0093 0.0093
Brugia malayi PH domain containing protein 0.0056 0.0107 0.0107
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.0093 0.0111
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica hypothetical protein, conserved 0.0051 0.0093 0.0588
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0051 0.0093 0.0111
Entamoeba histolytica PH domain containing protein 0.0056 0.0107 0.0677
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) Plekhf2 protein 0.0056 0.0107 0.0107
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.2168 0.2168
Leishmania major hypothetical protein, conserved 0.0056 0.0107 0.6645
Brugia malayi Pleckstrin Homology Domain 0.0056 0.0107 0.0107
Loa Loa (eye worm) CAMK protein kinase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0098 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Echinococcus multilocularis Immunoglobulin 0.0098 0.0217 0.0259
Echinococcus multilocularis dynamin 1 0.0056 0.0107 0.0128
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica receptor protein kinase, putative 0.0051 0.0093 0.0588
Schistosoma mansoni protein tyrosine kinase 0.0051 0.0093 0.0093
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0056 0.0107 0.0107
Brugia malayi Tyrosine-protein kinase abl-1 0.0051 0.0093 0.0093
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0051 0.0093 0.0111
Echinococcus granulosus tyrosine protein kinase Blk 0.0051 0.0093 0.0111
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0149 0.0942
Schistosoma mansoni vesicular amine transporter 0.01 0.0224 0.0224
Trypanosoma brucei Flagellum attachment zone protein 20 0.0051 0.0093 0.5768
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni hypothetical protein 0.0458 0.1172 0.1172
Brugia malayi Oxysterol-binding protein 0.0056 0.0107 0.0107
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0067 0.0135 0.836
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Onchocerca volvulus 0.0033 0.0044 0.0215
Leishmania major protein kinase, putative 0.0051 0.0093 0.5768
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0093 0.0093
Toxoplasma gondii protein kinase 0.0051 0.0093 0.5768
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0077 0.0162 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.003 0.0037 0.0799
Echinococcus granulosus mitogen activated protein kinase 0.0077 0.0162 0.0193
Loa Loa (eye worm) hypothetical protein 0.0614 0.1586 0.1586
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0051 0.0093 0.0093
Plasmodium vivax protein kinase, putative 0.0051 0.0093 0.5989
Plasmodium vivax tyrosine kinase-like protein, putative 0.0051 0.0093 0.5989
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0037 0.0233
Schistosoma mansoni zinc finger protein 0.0056 0.0107 0.0107
Trichomonas vaginalis centaurin alpha, putative 0.0056 0.0107 0.0677
Schistosoma mansoni fibrocystin l 0.0148 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Schistosoma mansoni serine/threonine RGC 0.0051 0.0093 0.0093
Leishmania major protein kinase, putative 0.0026 0.0026 0.1633
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Mycobacterium tuberculosis Probable esterase LipL 0.003 0.0037 0.0799
Mycobacterium tuberculosis Conserved protein 0.003 0.0037 0.0799
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0148 0.0351 0.2212
Echinococcus multilocularis ephrin type A receptor 4 A 0.0051 0.0093 0.0111
Plasmodium vivax tyrosine kinase-like protein, putative 0.0051 0.0093 0.5989
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0614 0.1586 0.1894
Brugia malayi Protein kinase domain containing protein 0.0289 0.0723 0.0723
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0051 0.0093 0.0111
Brugia malayi Protein kinase domain containing protein 0.0072 0.0149 0.0149
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0037 0.0233
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0051 0.0093 0.0111
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0072 0.0149 0.9237
Brugia malayi A-kinase anchor protein 10, precursor 0.0614 0.1586 0.1586
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Echinococcus granulosus dnaJ subfamily B 0.0494 0.1268 0.1514
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Trichomonas vaginalis centaurin/arf, putative 0.0056 0.0107 0.0677
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Brugia malayi Sema domain containing protein 0.0338 0.0855 0.0855
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0056 0.0106 0.0127
Loa Loa (eye worm) AGC/AKT protein kinase 0.0072 0.0149 0.0149
Echinococcus multilocularis musashi 0.0033 0.0044 0.0053
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0076 0.5007
Mycobacterium tuberculosis Probable hydrolase 0.003 0.0037 0.0799
Brugia malayi Sema domain containing protein 0.0338 0.0855 0.0855
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0162 0.102
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0077 0.4732
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0076 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Schistosoma mansoni hypothetical protein 0.0028 0.0034 0.0034
Echinococcus granulosus tyrosine protein kinase shark 0.0051 0.0093 0.0111
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0051 0.0093 0.0111
Entamoeba histolytica ARF GTPase activating protein, putative 0.0056 0.0107 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus granulosus tyrosine kinase 0.0051 0.0093 0.0111
Onchocerca volvulus outspread protein homolog 0.0056 0.0107 0.0519
Schistosoma mansoni growth factor receptor-bound protein 0.0056 0.0107 0.0107
Schistosoma mansoni goodpasture antigen-binding protein 0.0056 0.0107 0.0107
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Onchocerca volvulus Tyrosine kinase homolog 0.0051 0.0093 0.0451
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica protein kinase , putative 0.0075 0.0156 0.0982
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0093 0.0093
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0069 0.0436
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0064 0.1386
Loa Loa (eye worm) TK/FAK protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0149 0.0352 0.0352
Brugia malayi hypothetical protein 0.0043 0.0073 0.0073
Echinococcus multilocularis activated cdc42 kinase 1 0.0051 0.0093 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Echinococcus multilocularis GRB2 associated binding protein 3 0.0056 0.0107 0.0128
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.0093 0.0588
Brugia malayi intermediate filament protein 0.0033 0.0044 0.0044
Echinococcus granulosus tyrosine protein kinase ABL1 0.0051 0.0093 0.0111
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0073 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis c src tyrosine kinase 0.0051 0.0093 0.0111
Plasmodium falciparum protein kinase, putative 0.0051 0.0093 0.5989
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0001 0.0001
Echinococcus granulosus cytohesin 1 0.0056 0.0107 0.0128
Loa Loa (eye worm) sema domain-containing protein 0.0338 0.0855 0.0855
Loa Loa (eye worm) hypothetical protein 0.0796 0.2068 0.2068
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0098 0.0217 0.0217
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0056 0.0107 0.6645
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0067 0.0135 0.0161
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0051 0.0093 0.0111
Trichomonas vaginalis hypothetical protein 0.0056 0.0107 0.0677
Trypanosoma cruzi protein kinase, putative 0.0051 0.0093 0.5768
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Trichomonas vaginalis centaurin beta, putative 0.0056 0.0107 0.0677
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0149 0.0942
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Schistosoma mansoni serine/threonine-protein kinase 0.0072 0.0149 0.0149
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0051 0.0093 0.0093
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0044 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0051 0.0093 0.0111
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Echinococcus granulosus Oxysterol binding protein 11 0.0056 0.0107 0.0128
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0076 0.0091
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Echinococcus multilocularis exocyst complex component 2 0.0148 0.0351 0.0419
Echinococcus multilocularis mitogen activated protein kinase 0.0077 0.0162 0.0193
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0037 0.0233
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Onchocerca volvulus 0.0051 0.0093 0.0451
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0056 0.0107 0.0519
Entamoeba histolytica protein kinase domain containing protein 0.0075 0.0156 0.0982
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0044 0.0044
Echinococcus granulosus cGMP dependent protein kinase 0.0026 0.0026 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Mycobacterium ulcerans lipase LipD 0.003 0.0037 0.242
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0051 0.0093 0.0111
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0093 0.0111
Schistosoma mansoni oxysterol-binding protein 1 0.0056 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Leishmania major protein kinase, putative 0.0072 0.0149 0.9237
Echinococcus granulosus regulator of G protein signaling 7 0.0625 0.1614 0.1928
Echinococcus granulosus raf serine:threonine protein kinase 0.0051 0.0093 0.0111
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0051 0.0093 0.0111
Trypanosoma brucei PH domain containing protein, putative 0.0056 0.0107 0.6645
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0051 0.0093 0.5768
Mycobacterium tuberculosis Conserved protein 0.003 0.0037 0.0799
Schistosoma mansoni hypothetical protein 0.0056 0.0107 0.0107
Plasmodium falciparum calcium-dependent protein kinase 7 0.0072 0.0149 0.9591
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0223 0.055 0.266
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0077 0.0162 1
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0056 0.0107 0.6899
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0482
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0076 0.0091
Echinococcus granulosus insulin receptor 0.0051 0.0093 0.0111
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0051 0.0093 0.0111
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Brugia malayi Plexin repeat family protein 0.0796 0.2068 0.2068
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0614 0.1586 0.1586
Brugia malayi beta-lactamase family protein 0.003 0.0037 0.0037
Schistosoma mansoni protein kinase 0.0067 0.0135 0.0135
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0051 0.0093 0.0111
Loa Loa (eye worm) PXA domain-containing protein 0.0614 0.1586 0.1586
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0072 0.0149 0.9237
Plasmodium falciparum protein kinase, putative 0.0067 0.0135 0.868
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0072 0.0149 0.9237
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Loa Loa (eye worm) sema domain-containing protein 0.0338 0.0855 0.0855
Loa Loa (eye worm) SRC-1 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0103 0.023 0.023
Echinococcus multilocularis expressed protein 0.0614 0.1586 0.1894
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Brugia malayi protein-tyrosine kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0093 0.0588
Brugia malayi Immunoglobulin I-set domain containing protein 0.0149 0.0352 0.0352
Loa Loa (eye worm) syntrophin-1 0.0056 0.0107 0.0107
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0156 0.0982
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Echinococcus multilocularis GPCR, family 2 0.0019 0.0009 0.001
Loa Loa (eye worm) TK/INSR protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0037 0.0233
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0098 0.0217 0.0217
Loa Loa (eye worm) TK/CSK protein kinase 0.0051 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0148 0.0351 0.2212
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0056 0.0107 0.0677
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0026 0.0032
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0046 0.0081 0.0081
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0051 0.0093 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Entamoeba histolytica ankyrin repeat protein 0.0051 0.0093 0.0588
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0056 0.0107 0.0677
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0056 0.0107 0.0128
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.3173 0.8372 0.8372
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0077 0.0077
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0072 0.0149 0.9237
Trypanosoma cruzi PH domain containing protein, putative 0.0056 0.0107 0.6645
Schistosoma mansoni syntrophin 0.0056 0.0107 0.0107
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0056 0.0107 0.0677
Loa Loa (eye worm) hypothetical protein 0.0103 0.023 0.023
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0056 0.0107 0.0677
Loa Loa (eye worm) hypothetical protein 0.006 0.0118 0.0118
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Loa Loa (eye worm) hypothetical protein 0.0148 0.0351 0.0351
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0051 0.0093 0.0093
Echinococcus granulosus calcium dependent secretion activator 1 0.0056 0.0107 0.0128
Echinococcus multilocularis oxysterol binding protein 3 0.0056 0.0107 0.0128
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0093 0.0093
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0148 0.0351 0.2212
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Schistosoma mansoni protein kinase 0.0051 0.0093 0.0093
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Echinococcus granulosus GPCR family 2 0.0019 0.0009 0.001
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0153 0.0182
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0076 0.0481
Toxoplasma gondii protein kinase domain-containing protein 0.0072 0.0149 0.9237
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Schistosoma mansoni plexin 0.0796 0.2068 0.2068
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0614 0.1586 0.1586
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Onchocerca volvulus 0.003 0.0037 0.0178
Loa Loa (eye worm) TK/EGFR protein kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) RGS-3 protein 0.0614 0.1586 0.1586
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.003 0.0037 0.242
Echinococcus multilocularis neuroglian 0.0098 0.0217 0.0259
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0026 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.2903 0.7656 0.7656
Loa Loa (eye worm) TK/Met protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0075 0.0156 0.0156
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) TK/ABL protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Brugia malayi serine/threonine-protein kinase 6 0.0075 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.0028 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0351 0.2212
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0072 0.0149 0.0942
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0051 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Loa Loa (eye worm) inositol-1 0.0045 0.0076 0.0076
Brugia malayi beta-lactamase family protein 0.003 0.0037 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Brugia malayi Inositol-1 0.0045 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Mycobacterium tuberculosis Probable lipase LipE 0.003 0.0037 0.0799
Echinococcus granulosus Immunoglobulin 0.0098 0.0217 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Echinococcus multilocularis expressed conserved protein 0.0026 0.0026 0.0032
Schistosoma mansoni nephrin 0.0103 0.023 0.023
Echinococcus granulosus beta 1 syntrophin 0.0056 0.0107 0.0128
Brugia malayi hypothetical protein 0.0614 0.1586 0.1586
Loa Loa (eye worm) hypothetical protein 0.0338 0.0855 0.0855
Trypanosoma cruzi PH domain containing protein, putative 0.0056 0.0107 0.6645
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0205 0.0501 0.0501
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0156 0.0156
Entamoeba histolytica hypothetical protein 0.0072 0.0149 0.0942
Echinococcus multilocularis receptor type guanylyl cyclase 0.0051 0.0093 0.0111
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0051 0.0093 0.0111
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0051 0.0093 0.0588
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0056 0.0107 0.0128
Echinococcus granulosus oxysterol binding protein 3 0.0056 0.0107 0.0128
Echinococcus multilocularis tyrosine kinase 0.0051 0.0093 0.0111
Schistosoma mansoni plexin 0.0458 0.1172 0.1172
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.1439 0.1719
Echinococcus multilocularis protein kinase 0.0051 0.0093 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.2903 0.7656 0.7656
Echinococcus multilocularis insulin receptor 0.0051 0.0093 0.0111
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0098 0.0217 0.0217
Echinococcus granulosus aurora kinase A 0.0075 0.0156 0.0186
Echinococcus granulosus activin receptor type 0.0067 0.0135 0.0161
Toxoplasma gondii hypothetical protein 0.0056 0.0107 0.6645
Toxoplasma gondii STE kinase 0.0051 0.0093 0.5768
Entamoeba histolytica protein kinase, putative 0.0072 0.0149 0.0942
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Brugia malayi Guanylyl cyclase protein 23 0.0051 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Plasmodium falciparum oxysterol-binding protein, putative 0.0056 0.0107 0.6899
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0614 0.1586 0.1586
Loa Loa (eye worm) hypothetical protein 0.0614 0.1586 0.1586
Plasmodium vivax PH domain containing protein 0.0056 0.0107 0.6899
Leishmania major hypothetical protein, conserved 0.003 0.0037 0.2282
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0072 0.0149 0.9237
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.003 0.0037 0.0799
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0142 0.0169
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0056 0.0107 0.6899
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0149 0.0942
Echinococcus multilocularis tyrosine kinase 0.0051 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Echinococcus multilocularis tyrosine protein kinase 0.0051 0.0093 0.0111
Echinococcus granulosus semaphorin 5B 0.0338 0.0855 0.1021
Onchocerca volvulus 0.0021 0.0013 0.0063
Schistosoma mansoni regulator of G protein signaling 0.0614 0.1586 0.1586
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.2555 0.3052
Schistosoma mansoni tyrosine kinase 0.0051 0.0093 0.0093
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0072 0.0149 0.9237
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0076 0.4723
Loa Loa (eye worm) plexin A 0.0944 0.2461 0.2461
Loa Loa (eye worm) hypothetical protein 0.0338 0.0855 0.0855
Trypanosoma brucei protein kinase, putative 0.0072 0.0149 0.9237
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0077 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Lyn 0.0067 0.0135 0.0161
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0142 0.9296
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0056 0.0106 0.0127
Entamoeba histolytica hypothetical protein 0.0051 0.0093 0.0588
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0093 0.0588
Echinococcus multilocularis protein kinase 0.0051 0.0093 0.0111
Giardia lamblia Protein 21.1 0.0051 0.0093 0.5768
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0056 0.0107 0.6645
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0075 0.0156 0.0186
Entamoeba histolytica protein kinase, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Echinococcus multilocularis pleckstrin y domain containing family A 0.0056 0.0107 0.0128
Giardia lamblia Kinase, CMGC MAPK 0.0077 0.0162 1
Brugia malayi Protein kinase domain containing protein 0.0051 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0107
Trichomonas vaginalis protein transport protein sec7, putative 0.0056 0.0107 0.0677
Brugia malayi beta-lactamase 0.003 0.0037 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0588
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0051 0.0093 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0107 0.0677
Leishmania major hypothetical protein, conserved 0.0056 0.0107 0.6645
Schistosoma mansoni cpg binding protein 0.0037 0.0055 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0093 0.0093
Trypanosoma cruzi hypothetical protein 0.0056 0.0107 0.6645
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0093 0.0588
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0625 0.1614 0.1614
Schistosoma mansoni axis inhibition protein axin 0.0614 0.1586 0.1586
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0149 0.0942
Entamoeba histolytica PH domain containing protein 0.0056 0.0107 0.0677
Toxoplasma gondii aurora kinase 0.0075 0.0156 0.9631
Entamoeba histolytica hypothetical protein 0.0056 0.0107 0.0677
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Entamoeba histolytica tyrosin kinase, putative 0.0199 0.0486 0.3064
Echinococcus granulosus activated cdc42 kinase 1 0.0051 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0338 0.0855 0.0855

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.7943 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) = 3.1623 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) [Related pubchem assays: 1454, 995 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.581 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 84.9214 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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