Detailed information for compound 220342

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 487.964 | Formula: C24H18ClN7OS
  • H donors: 1 H acceptors: 4 LogP: 5.17 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1s/c(=N\C(=O)c2ccccc2Cl)/n(n1)Cc1ccc(cc1)c1ccccc1c1nn[nH]n1
  • InChi: 1S/C24H18ClN7OS/c1-15-29-32(24(34-15)26-23(33)20-8-4-5-9-21(20)25)14-16-10-12-17(13-11-16)18-6-2-3-7-19(18)22-27-30-31-28-22/h2-13H,14H2,1H3,(H,27,28,30,31)/b26-24-
  • InChiKey: JUABTCYRJQJDMB-LCUIJRPUSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Type-1B angiotensin II receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus growth hormone secretagogue receptor type 1 Type-1B angiotensin II receptor   359 aa 343 aa 23.0 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Type-1B angiotensin II receptor   359 aa 350 aa 23.1 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 309 aa 18.8 %
Loa Loa (eye worm) hypothetical protein Type-1B angiotensin II receptor   359 aa 308 aa 27.6 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 386 aa 24.4 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Type-1B angiotensin II receptor   359 aa 346 aa 18.2 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Type-1B angiotensin II receptor   359 aa 325 aa 20.9 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 355 aa 23.9 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Type-1B angiotensin II receptor   359 aa 366 aa 19.7 %
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Type-1B angiotensin II receptor   359 aa 300 aa 21.0 %
Schistosoma mansoni opsin-like receptor Type-1B angiotensin II receptor   359 aa 299 aa 25.8 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 305 aa 24.9 %
Loa Loa (eye worm) hypothetical protein Type-1B angiotensin II receptor   359 aa 329 aa 24.0 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Type-1B angiotensin II receptor   359 aa 363 aa 23.4 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 292 aa 24.7 %
Echinococcus granulosus thyrotropin releasing hormone receptor Type-1B angiotensin II receptor   359 aa 363 aa 23.7 %
Brugia malayi ORL1-like opioid receptor Type-1B angiotensin II receptor   359 aa 314 aa 20.4 %
Schistosoma mansoni peptide (allatostatin)-like receptor Type-1B angiotensin II receptor   359 aa 323 aa 25.7 %
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Type-1B angiotensin II receptor   359 aa 354 aa 20.6 %
Brugia malayi GnHR receptor homolog Type-1B angiotensin II receptor   359 aa 357 aa 20.4 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 314 aa 25.2 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Type-1B angiotensin II receptor   359 aa 365 aa 20.0 %
Echinococcus multilocularis G-protein coupled receptor, putative Type-1B angiotensin II receptor   359 aa 307 aa 22.1 %
Echinococcus granulosus allatostatin A receptor Type-1B angiotensin II receptor   359 aa 342 aa 27.2 %
Echinococcus granulosus neuropeptide receptor Type-1B angiotensin II receptor   359 aa 317 aa 24.6 %
Onchocerca volvulus Type-1B angiotensin II receptor   359 aa 350 aa 24.0 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Type-1B angiotensin II receptor   359 aa 307 aa 24.1 %
Echinococcus multilocularis neuropeptide receptor Type-1B angiotensin II receptor   359 aa 317 aa 24.9 %
Echinococcus multilocularis allatostatin A receptor Type-1B angiotensin II receptor   359 aa 342 aa 26.6 %
Echinococcus granulosus tm gpcr rhodopsin Type-1B angiotensin II receptor   359 aa 300 aa 21.0 %
Brugia malayi putative neuropeptide receptor NPR1 Type-1B angiotensin II receptor   359 aa 295 aa 27.1 %
Loa Loa (eye worm) neuropeptide F receptor Type-1B angiotensin II receptor   359 aa 344 aa 23.5 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi RE15519p 0.0313 0.0193 0.108
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0156 0.0089 0.0089
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0313 0.0193 0.108
Plasmodium falciparum orotate phosphoribosyltransferase 0.0091 0.0046 0.0046
Trypanosoma cruzi folylpolyglutamate synthetase 0.0153 0.0087 0.0489
Brugia malayi Tachykinin-like peptides receptor 99D 0.0313 0.0193 0.108
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0156 0.0089 0.0499
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.00000000012797
Trichomonas vaginalis glutathione reductase, putative 0.0027 0.0004 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0001 0.0005
Echinococcus multilocularis nmda type glutamate receptor 0.0206 0.0122 0.0683
Brugia malayi hypothetical protein 0.0134 0.0074 0.0417
Mycobacterium tuberculosis Conserved hypothetical protein 0.005 0.0019 0.0037
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0049 0.0018 0.0103
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0018 0.0018
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0081 0.0039 0.0221
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0091 0.0046 0.0042
Echinococcus multilocularis purine nucleoside phosphorylase 0.0045 0.0015 0.0086
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0153 0.0087 0.0087
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0074 0.0035 0.0195
Schistosoma mansoni lamin 0.0078 0.0037 0.0209
Toxoplasma gondii aminopeptidase N, putative 0.0028 0.0004 0.0004
Brugia malayi Heterochromatin protein 1 0.0084 0.0041 0.0231
Echinococcus multilocularis lysine specific demethylase 5A 0.0022 0.0001 0.0004
Mycobacterium tuberculosis Conserved protein 0.0023 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.003 0.0166
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0156 0.0089 0.0494
Loa Loa (eye worm) hypothetical protein 0.0333 0.0206 0.1154
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0218 0.013 0.0259
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0003 0.0014
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 1.5123 1 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0038 0.0011 0.006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0068 0.0031 0.0172
Echinococcus granulosus biogenic amine 5HT receptor 0.0313 0.0193 0.108
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0156 0.0089 0.0499
Loa Loa (eye worm) hypothetical protein 0.0184 0.0108 0.0603
Giardia lamblia NADH oxidase lateral transfer candidate 0.0027 0.0004 0.0009
Treponema pallidum folylpolyglutamate synthetase (folC) 0.0153 0.0087 0.0084
Schistosoma mansoni uracil phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0054 0.0021 0.0119
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0102 0.0053 0.0292
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0357 0.0222 0.0222
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0056 0.0023 0.0023
Brugia malayi GnHR receptor homolog 0.0313 0.0193 0.108
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0021
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0701 0.045 0.252
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0049 0.0018 0.0103
Mycobacterium tuberculosis Conserved protein 0.0091 0.0046 0.0091
Echinococcus granulosus neuropeptide receptor 0.0313 0.0193 0.108
Mycobacterium ulcerans zinc metalloprotease 0.0104 0.0054 0.0054
Leishmania major xanthine phosphoribosyltransferase 0.0388 0.0243 0.1359
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0049 0.0018 0.0103
Loa Loa (eye worm) hypothetical protein 0.0084 0.0041 0.0232
Schistosoma mansoni neuropeptide F-like receptor 0.0313 0.0193 0.108
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0022 0.0121
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0021 0.0117
Loa Loa (eye worm) hypothetical protein 0.0034 0.0008 0.0045
Echinococcus granulosus neuropeptides capa receptor 0.0313 0.0193 0.108
Brugia malayi chromobox protein homolog 3 0.0051 0.002 0.011
Leishmania major lanosterol synthase, putative 0.0027 0.0004 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0011 0.0059
Trypanosoma cruzi phytoene synthase, putative 0.0082 0.004 0.0225
Brugia malayi endonuclease G, mitochondrial precursor 0.0047 0.0017 0.0094
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0002 0.0008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.00000000012797
Schistosoma mansoni alpha-1 adrenergic receptor 0.0313 0.0193 0.108
Echinococcus multilocularis g-protein coupled receptor 0.0313 0.0193 0.108
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Echinococcus granulosus tm gpcr rhodopsin 0.0313 0.0193 0.108
Leishmania major ATP-dependent phosphofructokinase 0.0064 0.0028 0.0158
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.0388 0.0243 0.0242
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0313 0.0193 0.108
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0091 0.0046 0.0252
Plasmodium vivax aspartyl protease, putative 0.0034 0.0008 0.0008
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0218 0.013 0.0727
Echinococcus granulosus neuropeptide Y receptor 0.0313 0.0193 0.108
Echinococcus multilocularis somatostatin receptor 0.0313 0.0193 0.108
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0021 0.0000000000057596 0.000000000032248
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0701 0.045 1
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0079 0.0038 0.0212
Echinococcus granulosus glutamate receptor subunit protein glur 0.0068 0.0031 0.0172
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0701 0.045 0.252
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0211
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.2719 0.1786 1
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Loa Loa (eye worm) glutamate receptor 2 0.0132 0.0073 0.0409
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0313 0.0193 0.108
Plasmodium falciparum plasmepsin V 0.0034 0.0008 0.0008
Brugia malayi Peptidase family M1 containing protein 0.0028 0.0004 0.0023
Brugia malayi Intermediate filament tail domain containing protein 0.0078 0.0037 0.0209
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Echinococcus multilocularis fmrfamide receptor 0.0313 0.0193 0.108
Echinococcus multilocularis glutamate receptor NMDA 0.0046 0.0017 0.0093
Schistosoma mansoni hypothetical protein 0.0168 0.0097 0.0544
Trichomonas vaginalis esterase, putative 0.0023 0.0001 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0313 0.0193 0.108
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0313 0.0193 0.108
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0313 0.0193 0.108
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0002 0.0008
Brugia malayi SET domain containing protein 0.0024 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0008 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.019 0.0111 0.0111
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.001 0.0059
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0079 0.0038 0.0212
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0005
Echinococcus granulosus Squalene phytoene synthase 0.0082 0.004 0.0226
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0313 0.0193 0.108
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0018 0.0018
Echinococcus granulosus allatostatin A receptor 0.0313 0.0193 0.108
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.2719 0.1786 0.3576
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0001 0.0005
Echinococcus granulosus uridine 5' monophosphate synthase 0.0091 0.0046 0.0257
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0218 0.013 0.0727
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Schistosoma mansoni lipoxygenase 0.0033 0.0007 0.0041
Plasmodium falciparum thioredoxin reductase 0.0079 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0104 0.0054 0.0108
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus granulosus neutral sphingomyelinase 0.0034 0.0008 0.0047
Echinococcus multilocularis ectonucleotide 0.0066 0.0029 0.0164
Brugia malayi FolC bifunctional protein 0.0153 0.0087 0.0489
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0102 0.0053 0.0297
Toxoplasma gondii peptidase family M13 protein 0.0104 0.0054 0.0054
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0313 0.0193 0.108
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0158 0.009 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0001 0.0005
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.00000000012797
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0079 0.0038 0.0212
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0091 0.0046 0.0091
Trypanosoma cruzi Peptide deformylase 2, putative 0.0037 0.0011 0.0059
Toxoplasma gondii orotate phosphoribosyltransferase 0.0091 0.0046 0.0046
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0156 0.0089 0.0089
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0158 0.009 0.009
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0153 0.0087 0.0489
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0004 0.0021
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0064 0.0028 0.0153
Trypanosoma brucei endonuclease G, putative 0.0047 0.0017 0.0089
Brugia malayi MH2 domain containing protein 0.0124 0.0068 0.0379
Schistosoma mansoni blooms syndrome DNA helicase 0.0024 0.0002 0.0008
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0134 0.0074 0.0417
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0074 0.0035 0.0195
Schistosoma mansoni neprilysin 0.0027 0.0004 0.0021
Plasmodium vivax thioredoxin reductase, putative 0.0079 0.0038 0.0038
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0011 0.0059
Plasmodium falciparum plasmepsin VII 0.0034 0.0008 0.0008
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0047 0.0017 0.0094
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0017 0.0094
Onchocerca volvulus 0.0313 0.0193 0.6305
Echinococcus multilocularis G-protein coupled receptor, putative 0.0313 0.0193 0.108
Brugia malayi Dihydrofolate reductase 0.0158 0.009 0.0506
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0002 0.0004
Leishmania major hypothetical protein, conserved 0.0023 0.0001 0.0005
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.2719 0.1786 1
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Brugia malayi Angiotensin-converting enzyme family protein 0.0201 0.0119 0.0667
Brugia malayi Phosphoribosyl transferase domain containing protein 0.0388 0.0243 0.1359
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0068 0.0031 0.0172
Mycobacterium ulcerans lipase LipD 0.0023 0.0001 0.0001
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0218 0.013 0.0727
Mycobacterium ulcerans peptide deformylase 0.0098 0.0051 0.005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0079 0.0038 0.0075
Schistosoma mansoni glutamate receptor kainate 0.0132 0.0073 0.0409
Echinococcus multilocularis expressed protein 0.022 0.0131 0.0736
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0357 0.0222 0.1244
Schistosoma mansoni hypothetical protein 0.0037 0.001 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0054 0.0021 0.0119
Leishmania major DNA polymerase eta, putative 0.0036 0.001 0.0053
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0052 0.002 0.0114
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0017 0.0093
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0074 0.0035 0.0035
Schistosoma mansoni biogenic amine (5HT) receptor 0.0313 0.0193 0.108
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0179 0.0105 0.0209
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0025 0.0138
Onchocerca volvulus 0.0313 0.0193 0.6305
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.001 0.0053
Echinococcus multilocularis neuropeptide Y receptor 0.0313 0.0193 0.108
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0091 0.0046 0.0257
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0064 0.0028 0.0056
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0037 0.0209
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0156 0.0089 0.0499
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.0388 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0361 0.0225 0.126
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0018 0.0018
Onchocerca volvulus 0.0168 0.0097 0.3159
Schistosoma mansoni hypothetical protein 0.0313 0.0193 0.108
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0168 0.0097 0.0544
Loa Loa (eye worm) hypothetical protein 0.1308 0.0852 0.4771
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0735 0.0472 0.2644
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0029 0.0165
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0021
Onchocerca volvulus 0.0313 0.0193 0.6305
Entamoeba histolytica hypothetical protein 0.0134 0.0074 0.1655
Onchocerca volvulus 0.0068 0.0031 0.0978
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Echinococcus granulosus intermediate filament protein 0.0078 0.0037 0.0209
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0313 0.0193 0.108
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0313 0.0193 0.108
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0091 0.0046 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0156 0.0089 0.1981
Schistosoma mansoni hypothetical protein 0.0094 0.0048 0.0268
Plasmodium falciparum plasmepsin II 0.0142 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0068 0.0031 0.0172
Loa Loa (eye worm) hypothetical protein 0.0063 0.0027 0.0153
Loa Loa (eye worm) RGC/RGC protein kinase 0.0134 0.0074 0.0417
Schistosoma mansoni biogenic amine receptor 0.0313 0.0193 0.108
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0313 0.0193 0.108
Echinococcus granulosus lamin 0.0078 0.0037 0.0209
Plasmodium vivax aspartyl proteinase, putative 0.0142 0.008 0.008
Wolbachia endosymbiont of Brugia malayi phosphoribosylamine--glycine ligase 0.0046 0.0016 0.0012
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0243 0.1355
Loa Loa (eye worm) TATA binding protein associated factor 0.0028 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0313 0.0193 0.108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Brugia malayi Cytochrome P450 family protein 0.0038 0.0011 0.0063
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.2719 0.1786 0.1786
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.1359
Echinococcus granulosus neuropeptides capa receptor 0.0313 0.0193 0.108
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.2719 0.1786 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0091 0.0046 0.0257
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0733 0.0471 0.0943
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Echinococcus granulosus Chromobox protein 3 0.0021 0.0000000031731 0.000000017766
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0002 0.0012
Brugia malayi Hemopexin family protein 0.0094 0.0048 0.0268
Chlamydia trachomatis peptide deformylase 0.0098 0.0051 0.0047
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0255 0.0155 0.0868
Echinococcus granulosus Chromo domain 0.0021 0.0000000000057596 0.000000000032248
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0091 0.0046 0.0252
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus multilocularis G protein coupled receptor 139 0.0313 0.0193 0.108
Brugia malayi Serotonin receptor 0.0313 0.0193 0.108
Schistosoma mansoni amine GPCR 0.0313 0.0193 0.108
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0025 0.0003 0.0014
Echinococcus granulosus lysine specific demethylase 5A 0.0022 0.0001 0.0004
Plasmodium vivax aspartyl protease, putative 0.0034 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0701 0.045 0.252
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0027 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.024 0.0145 0.0809
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Leishmania major polyprenyl synthase, putative 0.0732 0.0471 0.2635
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus granulosus 7tm_1 domain containing protein 0.0313 0.0193 0.108
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0079 0.0038 0.0212
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0047 0.0017 0.0094
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus 0.0388 0.0243 0.7941
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0046 0.0257
Trypanosoma cruzi extracellular receptor, putative 0.0134 0.0074 0.0416
Schistosoma mansoni microtubule-associated protein tau 0.0931 0.0602 0.3373
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.1359
Onchocerca volvulus 0.0313 0.0193 0.6305
Brugia malayi aspartic protease BmAsp-1, identical 0.0034 0.0008 0.0045
Onchocerca volvulus 0.0483 0.0305 1
Echinococcus multilocularis neuropeptide receptor A26 0.0587 0.0374 0.2096
Leishmania major endonuclease G, putative 0.0047 0.0017 0.0094
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0017 0.0094
Mycobacterium ulcerans imidazoleglycerol-phosphate dehydratase 0.7564 0.4994 0.4994
Leishmania major farnesyltransferase beta subunit 0.0074 0.0035 0.0194
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.02 0.0118 0.0235
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0074 0.0035 0.0773
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0011 0.0059
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0091 0.0046 0.0046
Mycobacterium tuberculosis Probable lipase LipE 0.0023 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.019 0.0111 0.0624
Brugia malayi neuropeptide F receptor 0.0313 0.0193 0.108
Toxoplasma gondii aminopeptidase N protein 0.0028 0.0004 0.0004
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0000087481 0.0000087481
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0025 0.0003 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0013 0.0073
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0008 0.0046
Toxoplasma gondii aspartyl protease ASP3 0.0034 0.0008 0.0008
Brugia malayi Serotonin receptor 0.0313 0.0193 0.108
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0153 0.0087 0.0484
Mycobacterium ulcerans hypothetical protein 0.0091 0.0046 0.0046
Mycobacterium tuberculosis Probable imidazole glycerol-phosphate dehydratase HisB 0.7564 0.4994 1
Schistosoma mansoni opsin-like receptor 0.0313 0.0193 0.108
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0021 0.0117
Brugia malayi intermediate filament protein 0.0078 0.0037 0.0209
Trypanosoma cruzi aminopeptidase, putative 0.0028 0.0004 0.0023
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0102 0.0053 0.0297
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0032 0.0007 0.0039
Loa Loa (eye worm) hypothetical protein 0.0078 0.0037 0.0209
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0074 0.0035 0.0195
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0028 0.0158
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0018 0.0103
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0091 0.0046 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0008 0.0008
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0003 0.0014
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0063 0.0027 0.0153
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.2719 0.1786 1
Echinococcus multilocularis bloom syndrome protein 0.0034 0.0009 0.0048
Echinococcus granulosus peptide allatostatin:somatostatin 0.0313 0.0193 0.108
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0079 0.0038 0.0212
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0068 0.0031 0.0172
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Mycobacterium ulcerans aminopeptidase N PepN 0.0079 0.0038 0.0038
Leishmania major DNA polymerase kappa, putative 0.0025 0.0002 0.0012
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0054 0.0021 0.0119
Brugia malayi G-protein coupled receptor 0.0313 0.0193 0.108
Onchocerca volvulus 0.0313 0.0193 0.6305
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0041 0.0231
Onchocerca volvulus 0.0313 0.0193 0.6305
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0027 0.0004 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0001 0.0001
Echinococcus granulosus expressed conserved protein 0.0033 0.0008 0.0043
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0701 0.045 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0313 0.0193 0.108
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0054 0.0021 0.0119
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0142 0.008 0.0447
Onchocerca volvulus 0.0033 0.0007 0.0213
Plasmodium falciparum plasmepsin VI 0.0142 0.008 0.008
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0066 0.0029 0.0165
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0733 0.0471 0.0468
Loa Loa (eye worm) hypothetical protein 0.0077 0.0037 0.0204
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0357 0.0222 0.0222
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0313 0.0193 0.108
Echinococcus multilocularis chromobox protein 1 0.0084 0.0041 0.0231
Brugia malayi Matrixin family protein 0.0066 0.003 0.0166
Loa Loa (eye worm) hypothetical protein 0.0077 0.0037 0.0204
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0047 0.0017 0.0094
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0091 0.0046 0.0046
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0064 0.0028 0.0024
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0104 0.0054 0.0305
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0011 0.0059
Onchocerca volvulus 0.0218 0.013 0.4233
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus 0.0313 0.0193 0.6305
Onchocerca volvulus 0.0313 0.0193 0.6305
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0313 0.0193 0.108
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0011 0.001
Onchocerca volvulus 0.0313 0.0193 0.6305
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0102 0.0053 0.0297
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Loa Loa (eye worm) glutamate receptor 0.0419 0.0263 0.1473
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0066 0.0029 0.0164
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0313 0.0193 0.108
Mycobacterium ulcerans 6-phosphofructokinase 0.0064 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0024 0.0002 0.001
Brugia malayi calpain family protein 1 0.0063 0.0027 0.0153
Schistosoma mansoni neuropeptide receptor 0.0313 0.0193 0.108
Brugia malayi calpain family protein 1 0.0063 0.0027 0.0153
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0021 0.0000000000057596 0.0000000000057596
Echinococcus multilocularis GPCR, family 3, C terminal 0.0184 0.0108 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0005 0.003
Mycobacterium ulcerans phytoene synthase, CrtB 0.0082 0.004 0.004
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus granulosus metabotropic glutamate receptor 5 0.1308 0.0852 0.4771
Loa Loa (eye worm) matrix metalloproteinase 0.0066 0.003 0.0166
Loa Loa (eye worm) RGC/RGC protein kinase 0.0134 0.0074 0.0417
Loa Loa (eye worm) RGC/RGC protein kinase 0.0134 0.0074 0.0417
Echinococcus multilocularis serotonin receptor 0.0313 0.0193 0.108
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.1359
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0266 0.0162 0.0905
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0313 0.0193 0.108
Trypanosoma cruzi Peptide deformylase 2, putative 0.0037 0.0011 0.0059
Loa Loa (eye worm) CHromoDomain protein family member 0.0021 0.0000000000057596 0.000000000032248
Toxoplasma gondii hypothetical protein 0.0255 0.0155 0.0155
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0026 0.0146
Schistosoma mansoni hypothetical protein 0.0215 0.0128 0.0718
Echinococcus multilocularis neuropeptide receptor 0.0313 0.0193 0.108
Echinococcus granulosus tm gpcr rhodopsin 0.0313 0.0193 0.108
Echinococcus granulosus aminopeptidase N 0.0267 0.0163 0.0912
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0313 0.0193 0.108
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.019 0.0111 0.0111
Schistosoma mansoni aminopeptidase A (M01 family) 0.0028 0.0004 0.0023
Echinococcus granulosus 6 phosphofructokinase 0.0064 0.0028 0.0158
Schistosoma mansoni neuropeptide receptor 0.0313 0.0193 0.108
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0156 0.0089 0.0089
Mycobacterium leprae PROBABLE HYDROLASE 0.0081 0.0039 0.0039
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0027 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0047 0.0017 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Echinococcus granulosus receptor type guanylyl cyclase 0.0134 0.0074 0.0417
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0028 0.0004 0.0023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0179 0.0105 0.0209
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Loa Loa (eye worm) intermediate filament protein 0.0078 0.0037 0.0209
Echinococcus granulosus sex peptide receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Chlamydia trachomatis glutamine binding protein 0.0091 0.0046 0.0043
Brugia malayi peptidase family M13 containing protein 0.0025 0.0003 0.0014
Echinococcus multilocularis aminopeptidase N 0.0267 0.0163 0.0912
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Trypanosoma cruzi polyprenyl synthase, putative 0.0732 0.0471 0.2635
Entamoeba histolytica hypothetical protein 0.0037 0.001 0.0232
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0074 0.0035 0.0195
Loa Loa (eye worm) hypothetical protein 0.0034 0.0008 0.0045
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0047 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0142 0.008 0.0447
Echinococcus granulosus alpha 1A adrenergic receptor 0.0313 0.0193 0.108
Giardia lamblia Rab geranylgeranyltransferase 0.0102 0.0053 0.0285
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0001 0.0005
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.0297 0.0183 0.0365
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0732 0.0471 0.2635
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0091 0.0046 0.0092
Onchocerca volvulus 0.0044 0.0015 0.046
Echinococcus multilocularis Chromo domain 0.0021 0.0000000000057596 0.000000000032248
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0001 0.0001
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0028 0.0004 0.0023
Brugia malayi orotate phosphoribosyltransferase family protein 0.0091 0.0046 0.0257
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.094 0.0608 0.3404
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0357 0.0222 0.1244
Toxoplasma gondii hypothetical protein 0.0041 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0063 0.0027 0.0153
Echinococcus granulosus neuropeptide FF receptor 2 0.0313 0.0193 0.108
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0091 0.0046 0.0257
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0098 0.0051 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Echinococcus granulosus hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus 0.0134 0.0074 0.2413
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0026 0.0146
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0021 0.0000000000057596 0.0000000000057596
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0026 0.0146
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0027 0.0004 0.0003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.02 0.0118 0.0235
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0027 0.0004 0.0016
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0733 0.0471 0.0943
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0028 0.0004 0.0023
Giardia lamblia Prenyltransferase 0.0074 0.0035 0.0183
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0021
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.006 0.0026 0.0026
Mycobacterium ulcerans hydrolase 0.0081 0.0039 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Trypanosoma cruzi Protein of unknown function (DUF971), putative 0.0023 0.0001 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0044 0.0015 0.0084
Trypanosoma cruzi protein farnesyltransferase, putative 0.0074 0.0035 0.0194
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0701 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0076 0.0036 0.0204
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0021
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0102 0.0053 0.0297
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.002 0.0611
Trypanosoma cruzi endonuclease G, putative 0.0047 0.0017 0.0094
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus multilocularis neuropeptide Y receptor 0.0313 0.0193 0.108
Echinococcus granulosus neuropeptide Y receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0146 0.0083 0.0165
Echinococcus multilocularis glutamate receptor 2 0.0132 0.0073 0.0409
Treponema pallidum hypothetical protein 0.0091 0.0046 0.0042
Onchocerca volvulus 0.0079 0.0038 0.1213
Echinococcus granulosus microtubule associated protein 2 0.0931 0.0602 0.3373
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0021 0.0117
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.2719 0.1786 0.1786
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Echinococcus multilocularis tyrosine kinase 0.0134 0.0074 0.0417
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0045 0.0015 0.0086
Echinococcus granulosus ectonucleotide 0.0066 0.0029 0.0164
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Echinococcus multilocularis purine nucleoside phosphorylase 0.0045 0.0015 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.002 0.011
Schistosoma mansoni neuropeptide receptor 0.0313 0.0193 0.108
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0032 0.0007 0.0007
Schistosoma mansoni glutamate receptor AMPA 0.0132 0.0073 0.0409
Onchocerca volvulus 0.0078 0.0037 0.1194
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0037 0.0011 0.0059
Plasmodium falciparum conserved protein, unknown function 0.0023 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0037 0.0204
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0124 0.0068 0.0379
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0313 0.0193 0.108
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0026 0.0146
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.1359
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.001 0.0053
Entamoeba histolytica phosphofructokinase, putative 0.0064 0.0028 0.0627
Loa Loa (eye worm) thioredoxin reductase 0.0079 0.0038 0.0212
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Brugia malayi aspartic protease BmAsp-2, identical 0.0034 0.0008 0.0045
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0091 0.0046 0.1478
Mycobacterium tuberculosis Probable oxidoreductase 0.02 0.0118 0.0235
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0073 0.0034 0.0191
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0034 0.0008 0.0016
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0218 0.013 0.0129
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0357 0.0222 0.1244
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0313 0.0193 0.108
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0051 0.002 0.011
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0091 0.0046 0.0046
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0266 0.0162 0.0905
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0218 0.013 0.0716
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.001 0.0048
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0156 0.0089 0.0499
Toxoplasma gondii MRP family domain-containing protein 0.0023 0.0001 0.0001
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0017 0.0094
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0068 0.0031 0.0172
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.0267 0.1493
Schistosoma mansoni hypothetical protein 0.0313 0.0193 0.108
Trypanosoma brucei Peptide deformylase 2 0.0037 0.0011 0.0054
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0091 0.0046 0.0257
Mycobacterium leprae Probable lipase LipE 0.0023 0.0001 0.0001
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0037 0.0011 0.0059
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0042
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.019 0.0111 0.0624
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Brugia malayi Bloom's syndrome protein homolog 0.0034 0.0009 0.0048
Brugia malayi G-protein coupled receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) matrixin family protein 0.016 0.0092 0.0514
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0032 0.0007 0.0039
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0156 0.0089 0.0499
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0082 0.004 0.1292
Echinococcus granulosus Endonuclease G 0.0047 0.0017 0.0094
Trypanosoma brucei Polypeptide deformylase 1 0.0037 0.0011 0.0054
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0078 0.0037 0.0209
Loa Loa (eye worm) neuropeptide F receptor 0.0313 0.0193 0.108
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) glutamate receptor 0.1074 0.0697 0.3901
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.0146
Trichomonas vaginalis DNA helicase recq1, putative 0.0034 0.0009 0.0048
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Echinococcus granulosus endothelin converting enzyme 1 0.0104 0.0054 0.0305
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0082 0.004 0.0226
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.0001 0.0005
Brugia malayi Pre-SET motif family protein 0.0424 0.0267 0.1493
Echinococcus multilocularis nmda type glutamate receptor 0.018 0.0105 0.0589
Loa Loa (eye worm) dihydrofolate reductase 0.0158 0.009 0.0506
Plasmodium falciparum plasmepsin I 0.0142 0.008 0.008
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0142 0.008 0.0447
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0054 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0005
Trypanosoma cruzi Protein of unknown function (DUF971), putative 0.0023 0.0001 0.0005
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0074 0.0035 0.0195
Loa Loa (eye worm) follicle stimulating hormone receptor 0.05 0.0317 0.1773
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0357 0.0222 0.1244
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0056 0.0023 0.0045
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0218 0.013 0.0727
Loa Loa (eye worm) RecQ helicase 0.0034 0.0009 0.0048
Leishmania major folylpolyglutamate synthetase 0.0153 0.0087 0.0489
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0046 0.0257
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0091 0.0046 0.0257
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0732 0.0471 0.2635
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0091 0.0046 0.0257
Plasmodium vivax plasmepsin V, putative 0.0034 0.0008 0.0008
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0073 0.0034 0.0191
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0357 0.0222 0.1244
Loa Loa (eye worm) hypothetical protein 0.0104 0.0054 0.0305
Trypanosoma brucei aminopeptidase, putative 0.0028 0.0004 0.0018
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0051 0.002 0.011
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0091 0.0046 0.0046
Echinococcus multilocularis conserved hypothetical protein 0.0033 0.0008 0.0043
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0091 0.0046 0.0091
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0313 0.0193 0.108
Schistosoma mansoni jumonji/arid domain-containing protein 0.0022 0.0001 0.0004
Schistosoma mansoni purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0483 0.0306 0.1711
Trypanosoma brucei squalene synthase, putative 0.0264 0.0161 0.0895
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0153 0.0087 0.0489
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Brugia malayi G protein-coupled receptor 0.0313 0.0193 0.108
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0122 0.0067 0.0374
Toxoplasma gondii aldehyde dehydrogenase 0.0049 0.0018 0.0018
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0701 0.045 0.045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Plasmodium vivax aspartyl protease, putative 0.0034 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0313 0.0193 0.108
Brugia malayi Pepsin A precursor 0.0034 0.0008 0.0045
Mycobacterium leprae probable zinc metalloprotease 0.0104 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.002 0.011
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0091 0.0046 0.0257
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0074 0.0035 0.0195
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0091 0.0046 0.0042
Echinococcus multilocularis receptor type guanylyl cyclase 0.0134 0.0074 0.0417
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0074 0.0035 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0028 0.0004 0.0023
Echinococcus multilocularis Chromobox protein 3 0.0021 0.0000000031731 0.000000017766
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0008 0.0008
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0027 0.0004 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0266 0.0162 0.0905
Mycobacterium tuberculosis Probable lipase LipD 0.0023 0.0001 0.0001
Schistosoma mansoni farnesyl pyrophosphate synthase 0.2719 0.1786 1
Echinococcus multilocularis orexin receptor type 2 0.0313 0.0193 0.108
Toxoplasma gondii hypothetical protein 0.0098 0.0051 0.0051
Brugia malayi Thioredoxin reductase 0.0079 0.0038 0.0212
Trypanosoma brucei lanosterol synthase 0.0047 0.0017 0.009
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0098 0.0051 0.0101
Schistosoma mansoni endonuclease related 0.0047 0.0017 0.0094
Brugia malayi Adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Onchocerca volvulus 0.0313 0.0193 0.6305
Echinococcus multilocularis Endonuclease G 0.0047 0.0017 0.0094
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0002 0.0036
Echinococcus granulosus g protein coupled receptor 0.0313 0.0193 0.108
Echinococcus granulosus farnesyl pyrophosphate synthase 0.2719 0.1786 1
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0218 0.013 0.0727
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0068 0.0379
Leishmania major adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0047 0.0017 0.0094
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0037 0.0209
Schistosoma mansoni hypothetical protein 0.0149 0.0085 0.0474
Trichomonas vaginalis mercuric reductase, putative 0.0027 0.0004 0.0022
Echinococcus multilocularis glutamate receptor 2 0.0266 0.0162 0.0905
Trypanosoma brucei trypanothione reductase 0.0079 0.0038 0.0207
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0066 0.0029 0.0164
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0074 0.0035 0.0195
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0017 0.0094
Brugia malayi Thrombospondin type 1 domain containing protein 0.0168 0.0097 0.0544
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0179 0.0105 0.0209
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0000000000057596 0.0000000000057596
Loa Loa (eye worm) 6-phosphofructokinase 0.0064 0.0028 0.0158
Schistosoma mansoni chromobox protein 0.0084 0.0041 0.0231
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0047 0.0017 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0211
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0000000000057596 0.000000000032248
Onchocerca volvulus 0.0102 0.0053 0.1711
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0153 0.0087 0.0489
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0051 0.002 0.011
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Echinococcus multilocularis g protein coupled receptor 0.0313 0.0193 0.108
Mycobacterium ulcerans hypothetical protein 0.005 0.0019 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.001 0.0059
Schistosoma mansoni glutamate receptor kainate 0.0132 0.0073 0.0409
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0156 0.0089 0.0499
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Trypanosoma cruzi lanosterol synthase, putative 0.0047 0.0017 0.0095
Loa Loa (eye worm) aminopeptidase N 0.0079 0.0038 0.0212
Schistosoma mansoni hypothetical protein 0.0068 0.0031 0.0172
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0073 0.0034 0.0191
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0102 0.0053 0.0297
Schistosoma mansoni hypothetical protein 0.0313 0.0193 0.108
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0156 0.0089 0.0499
Mycobacterium leprae conserved hypothetical protein 0.005 0.0019 0.0018
Schistosoma mansoni glutamate receptor AMPA 0.0132 0.0073 0.0409
Schistosoma mansoni neuropeptide F-like receptor 0.0313 0.0193 0.108
Plasmodium falciparum peptide deformylase 0.0098 0.0051 0.0051
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0091 0.0046 0.0046
Entamoeba histolytica phosphofructokinase, putative 0.0064 0.0028 0.0627
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0357 0.0222 0.4938
Loa Loa (eye worm) FolC protein 0.0153 0.0087 0.0489
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0313 0.0193 0.108
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.0297 0.0183 0.0182
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0064 0.0028 0.0158
Loa Loa (eye worm) hypothetical protein 0.0046 0.0017 0.0093
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0034 0.0008 0.0045
Schistosoma mansoni amine GPCR 0.0313 0.0193 0.108
Plasmodium vivax plasmepsin IV, putative 0.0142 0.008 0.008
Onchocerca volvulus 0.0134 0.0074 0.2413
Echinococcus multilocularis endothelin converting enzyme 1 0.0104 0.0054 0.0305
Schistosoma mansoni survival motor neuron protein 0.0068 0.0031 0.0172
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.0001 0.0005
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0001 0.0001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0027 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0078 0.0037 0.0209
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0266 0.0162 0.0905
Schistosoma mansoni 6-phosphofructokinase 0.0064 0.0028 0.0158
Onchocerca volvulus 0.0313 0.0193 0.6305
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0018 0.0099
Brugia malayi Matrixin family protein 0.0066 0.003 0.0166
Schistosoma mansoni memapsin-2 (A01 family) 0.0034 0.0008 0.0045
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0153 0.0087 0.0087
Brugia malayi Dopamine receptor protein 2 0.0313 0.0193 0.108
Leishmania major solanesyl-diphosphate synthase, putative 0.0701 0.045 0.2519
Onchocerca volvulus 0.0078 0.0037 0.1196
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0318 0.0196 0.1099
Treponema pallidum octaprenyl-diphosphate synthase 0.0732 0.0471 0.0467
Mycobacterium tuberculosis Probable esterase LipL 0.0023 0.0001 0.0001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0022 0.0121
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0149 0.0085 0.0474
Brugia malayi hypothetical protein 0.0028 0.0004 0.0023
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0005 0.003
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0021 0.0117
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0102 0.0053 0.0297
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Brugia malayi Matrixin family protein 0.0066 0.003 0.0166
Trypanosoma brucei farnesyl pyrophosphate synthase 0.2719 0.1786 1
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0028 0.0004 0.0023
Brugia malayi Peptidase family M1 containing protein 0.0267 0.0163 0.0912
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0098 0.0051 0.005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0313 0.0193 0.108
Leishmania major hypothetical protein, conserved 0.0082 0.004 0.0225
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0011 0.0059
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0218 0.013 0.0727
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0701 0.045 0.252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Toxoplasma gondii aminopeptidase n, putative 0.0028 0.0004 0.0004
Plasmodium falciparum glutathione reductase 0.0027 0.0004 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0011 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0023
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0091 0.0046 0.0043
Loa Loa (eye worm) hypothetical protein 0.0081 0.0039 0.0219
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0038 0.0212
Echinococcus multilocularis Squalene phytoene synthase 0.0082 0.004 0.0226
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0142 0.008 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0027 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.005 0.0019 0.0587
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0038
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0064 0.0028 0.0028
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0054 0.0021 0.0473
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0102 0.0053 0.0297
Trypanosoma cruzi endonuclease G, putative 0.0047 0.0017 0.0094
Echinococcus granulosus g-protein coupled receptor 0.0313 0.0193 0.108
Entamoeba histolytica phosphofructokinase, putative 0.0064 0.0028 0.0627
Brugia malayi hypothetical protein 0.0034 0.0008 0.0045
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0889 0.0575 0.3218
Echinococcus granulosus neuropeptide s receptor 0.0587 0.0374 0.2096
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0082 0.004 0.008
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0003 0.0014
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Echinococcus granulosus dna polymerase kappa 0.0037 0.0011 0.0059
Toxoplasma gondii thioredoxin reductase 0.0079 0.0038 0.0038
Echinococcus multilocularis neuropeptide s receptor 0.0587 0.0374 0.2096
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0033 0.0007 0.0041
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0011 0.0059
Brugia malayi ORL1-like opioid receptor 0.0313 0.0193 0.108
Brugia malayi AKH receptor 0.0313 0.0193 0.108
Mycobacterium tuberculosis Probable hydrolase 0.0023 0.0001 0.0001
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.2719 0.1786 0.1786
Onchocerca volvulus 0.0078 0.0037 0.1194
Loa Loa (eye worm) hypothetical protein 0.0021 0.0000000000057596 0.000000000032248
Loa Loa (eye worm) G-protein coupled receptor 0.0313 0.0193 0.108
Schistosoma mansoni DNA polymerase eta 0.0036 0.001 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0601 0.0384 0.2148
Toxoplasma gondii aspartyl protease 0.0034 0.0008 0.0008
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0091 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0318 0.0196 0.1099
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0028 0.0004 0.0023
Schistosoma mansoni myosin xvIII 0.0313 0.0193 0.108
Loa Loa (eye worm) calpain family protein 1 0.0044 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0051 0.002 0.011
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0056 0.0023 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0001 0.0005
Trypanosoma cruzi squalene synthase, putative 0.0264 0.0161 0.0899
Schistosoma mansoni metabotropic glutamate receptor 0.0553 0.0352 0.197
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0004 0.0016
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0028 0.0004 0.0023
Trypanosoma cruzi polyprenyl synthase, putative 0.0732 0.0471 0.2635
Toxoplasma gondii ABC1 family protein 0.0023 0.0001 0.0001
Onchocerca volvulus 0.0028 0.0004 0.0103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Trypanosoma cruzi aminopeptidase, putative 0.0079 0.0038 0.0212
Schistosoma mansoni tyrosine kinase 0.0134 0.0074 0.0417
Echinococcus multilocularis 6 phosphofructokinase 0.0064 0.0028 0.0158
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0011 0.0059
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0184 0.0108 0.0603
Loa Loa (eye worm) aspartyl protease 6 0.0034 0.0008 0.0045
Brugia malayi Guanylyl cyclase protein 23 0.0134 0.0074 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0102 0.0053 0.0297
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0027 0.0004 0.0022
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0017 0.0093
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0027 0.0004 0.0021
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Echinococcus granulosus glutamate receptor NMDA 0.0046 0.0017 0.0093
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Schistosoma mansoni glutathione synthetase 0.0701 0.045 0.252
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0008 0.0038
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.2719 0.1786 0.1786
Onchocerca volvulus 0.0267 0.0163 0.5315
Loa Loa (eye worm) peptidase family M13 containing protein 0.0077 0.0037 0.0204
Onchocerca volvulus 0.0034 0.0008 0.0232
Trypanosoma cruzi protein farnesyltransferase, putative 0.0074 0.0035 0.0194
Plasmodium vivax peptide deformylase, putative 0.0098 0.0051 0.0051
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0024 0.0002 0.0031
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.2719 0.1786 1
Schistosoma mansoni biogenic amine receptor 0.0313 0.0193 0.108
Brugia malayi beta-lactamase family protein 0.0023 0.0001 0.0005
Leishmania major trypanothione reductase 0.0079 0.0038 0.0212
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0023 0.0001 0.0001
Echinococcus granulosus calpain A 0.0066 0.0029 0.0165
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0028 0.0004 0.0004
Echinococcus multilocularis expressed conserved protein 0.0033 0.0008 0.0043
Echinococcus multilocularis dro:myosuppressin receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0023
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0313 0.0193 0.108
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0028 0.0158
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0218 0.013 0.0727
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.0153 0.0087 0.0174
Toxoplasma gondii NADPH-glutathione reductase 0.0027 0.0004 0.0004
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0243 0.0243
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0701 0.045 0.045
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0028 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0091 0.0046 0.0252
Brugia malayi Polyprenyl synthetase family protein 0.0701 0.045 0.252
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Giardia lamblia Farnesyl diphosphate synthase 0.2719 0.1786 1
Plasmodium vivax SET domain protein, putative 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0077 0.0037 0.0204
Trypanosoma cruzi squalene synthase, putative 0.0264 0.0161 0.0899
Onchocerca volvulus 0.0094 0.0048 0.1555
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.1174 0.0763 0.4275
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0158 0.009 0.018
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0091 0.0046 0.0091
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0011 0.0054
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0102 0.0053 0.0053
Schistosoma mansoni jumonji/arid domain-containing protein 0.0022 0.0001 0.0004
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0732 0.0471 0.2635
Echinococcus multilocularis g protein coupled receptor 0.0313 0.0193 0.108
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0091 0.0046 0.0043
Echinococcus granulosus nmda type glutamate receptor 0.0206 0.0122 0.0683
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 1.5123 1 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0047 0.0017 0.0089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0023 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0044 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0211
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0134 0.0074 0.0417
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Trypanosoma brucei endonuclease G, putative 0.0047 0.0017 0.0089
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0011 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0102 0.0053 0.0292
Echinococcus multilocularis NMDA receptor 0.0068 0.0031 0.0172
Brugia malayi Glutamate receptor 2 precursor 0.0132 0.0073 0.0409
Brugia malayi 6-phosphofructokinase 0.0064 0.0028 0.0158
Schistosoma mansoni glutamate receptor kainate 0.0132 0.0073 0.0409
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0701 0.045 0.2519
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0013 0.0073
Onchocerca volvulus 0.0313 0.0193 0.6305
Brugia malayi follicle stimulating hormone receptor 0.05 0.0317 0.1773
Trichomonas vaginalis set domain proteins, putative 0.0483 0.0305 0.171
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0001 0.0001
Plasmodium falciparum thioredoxin reductase 0.0027 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Brugia malayi Matrixin family protein 0.0066 0.003 0.0166
Loa Loa (eye worm) hypothetical protein 0.0104 0.0054 0.0305
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0241 0.0145 0.0812
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0142 0.008 0.0447
Loa Loa (eye worm) hypothetical protein 0.0066 0.003 0.0166
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0000000000057596 0.000000000032248
Onchocerca volvulus 0.0313 0.0193 0.6305
Brugia malayi M-phase phosphoprotein, mpp8 0.0094 0.0048 0.027
Trypanosoma brucei Aminopeptidase M1, putative 0.0079 0.0038 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0017 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Onchocerca volvulus 0.0313 0.0193 0.6305
Echinococcus granulosus chromobox protein 1 0.0084 0.0041 0.0231
Echinococcus granulosus chromobox protein 1 0.0084 0.0041 0.0231
Loa Loa (eye worm) hypothetical protein 0.0051 0.002 0.0111
Toxoplasma gondii aspartyl protease ASP1 0.0142 0.008 0.008
Brugia malayi 6-phosphofructokinase 0.0064 0.0028 0.0158
Echinococcus granulosus hypothetical protein 0.0033 0.0008 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.0153 0.0087 0.0087
Onchocerca volvulus Matrilysin homolog 0.0147 0.0083 0.2693
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0005
Echinococcus granulosus dna polymerase eta 0.0036 0.001 0.0053
Entamoeba histolytica hypothetical protein 0.0021 0.0000000000057596 0.00000000012797
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0074 0.0035 0.0195
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0153 0.0087 0.0087
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0156 0.0089 0.0499
Loa Loa (eye worm) melatonin receptor type 1A 0.0313 0.0193 0.108
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0033 0.0007 0.0041
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0021 0.0114
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0074 0.0035 0.019
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0029 0.0165
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Leishmania major dihydrofolate reductase-thymidylate synthase 0.006 0.0026 0.0144
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0026 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0013 0.0073
Echinococcus multilocularis lamin 0.0078 0.0037 0.0209
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0028 0.0004 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0068 0.0379
Loa Loa (eye worm) G-protein coupled receptor 0.0313 0.0193 0.108
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0091 0.0046 0.0091
Schistosoma mansoni lamin 0.0078 0.0037 0.0209
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0028 0.0158
Mycobacterium tuberculosis Probable reductase 0.0179 0.0105 0.0209
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0081 0.0039 0.0219
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0156 0.0089 0.0499
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.02 0.0118 0.0118
Echinococcus granulosus dro:myosuppressin receptor 0.0313 0.0193 0.108
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0027 0.0004 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0004 0.0021
Trypanosoma brucei endonuclease G, putative 0.0047 0.0017 0.0089
Mycobacterium ulcerans esterase/lipase LipP 0.0023 0.0001 0.0001
Brugia malayi Peptidase family M1 containing protein 0.0079 0.0038 0.0212
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0052 0.002 0.0114
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0027 0.0004 0.0003
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0056 0.0023 0.0116
Leishmania major squalene synthase, putative 0.0264 0.0161 0.0899
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0056 0.0023 0.0129
Brugia malayi TATA binding protein associated factor 0.0028 0.0004 0.0023
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0153 0.0087 0.0489
Schistosoma mansoni hypothetical protein 0.0313 0.0193 0.108
Leishmania major farnesyl pyrophosphate synthase 0.2719 0.1786 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0313 0.0193 0.108
Mycobacterium leprae PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT 0.0046 0.0016 0.0016
Onchocerca volvulus 0.0066 0.003 0.0941
Loa Loa (eye worm) hypothetical protein 0.0104 0.0054 0.0305
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0028 0.0004 0.0023
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0179 0.0105 0.0104
Schistosoma mansoni neutral sphingomyelinase 0.0034 0.0008 0.0047
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0102 0.0053 0.0297
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Echinococcus multilocularis microtubule associated protein 2 0.0931 0.0602 0.3373
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0159 0.0091 0.0511
Schistosoma mansoni opsin-like receptor 0.0313 0.0193 0.108
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0008 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.0021 0.0117
Mycobacterium ulcerans beta-lactamase 0.0023 0.0001 0.0001
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0021 0.0117
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0313 0.0193 0.108
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0357 0.0222 0.1244
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0102 0.0053 0.0297
Brugia malayi Polyprenyl synthetase family protein 0.2719 0.1786 1
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0074 0.0035 0.0195
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0028 0.0004 0.0023
Brugia malayi Dopamine receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) polyprenyl synthetase 0.0701 0.045 0.252
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0017 0.0512
Schistosoma mansoni trans-prenyltransferase 0.0701 0.045 0.252
Brugia malayi polk-prov protein 0.0023 0.0001 0.0007
Schistosoma mansoni metabotropic glutamate receptor 0.0889 0.0575 0.3218
Brugia malayi hypothetical protein 0.0079 0.0038 0.0212
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0701 0.045 0.2519
Schistosoma mansoni biogenic amine (5HT) receptor 0.0313 0.0193 0.108
Echinococcus granulosus serotonin receptor 0.0313 0.0193 0.108
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0313 0.0193 0.108
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0066 0.0029 0.0165
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0074 0.0035 0.0195
Echinococcus granulosus leukotriene A 4 hydrolase 0.0028 0.0004 0.0023
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0243 0.1359
Brugia malayi phosphofructokinase 0.0064 0.0028 0.0158
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0021 0.0000000000057596 0.000000000032248
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0313 0.0193 0.108
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0149 0.0085 0.0474
Plasmodium falciparum plasmepsin VIII, putative 0.0034 0.0008 0.0008
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Brugia malayi glutathione reductase 0.0079 0.0038 0.0212
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0042 0.0013 0.0075
Trypanosoma cruzi lanosterol synthase, putative 0.0047 0.0017 0.0095
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0156 0.0089 0.0499
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0000000000057596 0.000000000032248
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.2719 0.1786 0.1786
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0102 0.0053 0.0297
Plasmodium vivax aspartyl proteinase, putative 0.0034 0.0008 0.0008
Echinococcus multilocularis thioredoxin glutathione reductase 0.0079 0.0038 0.0212
Leishmania major extracellular receptor, putative 0.0134 0.0074 0.0416
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0017 0.0093
Loa Loa (eye worm) MBCTL1 0.0053 0.0021 0.0117
Echinococcus granulosus glutamate receptor 2 0.0198 0.0117 0.0654
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0357 0.0222 0.1244
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0046 0.0257
Brugia malayi Matrixin family protein 0.016 0.0092 0.0514
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0011 0.0063
Loa Loa (eye worm) hypothetical protein 0.0045 0.0015 0.0086
Schistosoma mansoni amine GPCR 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0007
Echinococcus granulosus G protein coupled receptor 139 0.0313 0.0193 0.108
Echinococcus granulosus neuropeptide receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Brugia malayi hypothetical protein 0.0171 0.0099 0.0556
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.005 0.0019 0.0018
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.0243
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0028 0.0158
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0005
Schistosoma mansoni amine GPCR 0.0313 0.0193 0.108
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0018 0.0103
Schistosoma mansoni hypothetical protein 0.0021 0.0000000000057596 0.000000000032248
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0021 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0011 0.0054
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0179 0.0105 0.0209
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0011 0.0063
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0079 0.0038 0.0212
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0266 0.0162 0.0905
Loa Loa (eye worm) hypothetical protein 0.0095 0.0048 0.0271
Schistosoma mansoni glutamate receptor NMDA 0.0312 0.0192 0.1078
Onchocerca volvulus 0.0082 0.004 0.1291
Onchocerca volvulus Putative neutral sphingomyelinase 0.0034 0.0008 0.0241
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0106
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0104 0.0054 0.0305
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0266 0.0162 0.0905
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0054 0.0021 0.0119
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0028 0.0004 0.0023
Brugia malayi hypothetical protein 0.0095 0.0048 0.0271
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0037 0.0209
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0091 0.0046 0.0046
Echinococcus granulosus expressed protein 0.022 0.0131 0.0736
Schistosoma mansoni cathepsin D (A01 family) 0.0419 0.0263 0.1473
Schistosoma mansoni neuropeptide f receptor 76f 0.0313 0.0193 0.108
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0001 0.0005
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.006
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.2719 0.1786 1
Leishmania major polypeptide deformylase-like protein, putative 0.0037 0.0011 0.0059
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0021 0.0117
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0134 0.0074 0.2413
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Plasmodium falciparum plasmepsin IV 0.0142 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0041 0.0231
Toxoplasma gondii hypothetical protein 0.0102 0.0053 0.0053
Mycobacterium tuberculosis Conserved protein 0.0091 0.0046 0.0091
Loa Loa (eye worm) beta-lactamase 0.0023 0.0001 0.0005
Echinococcus granulosus lamin dm0 0.0078 0.0037 0.0209
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0038 0.0212
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0017 0.0093
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Entamoeba histolytica hypothetical protein 0.0037 0.001 0.0232
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0073 0.0034 0.0191
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0102 0.0053 0.0292
Echinococcus granulosus glutamate NMDA receptor subunit 0.0229 0.0138 0.0771
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0313 0.0193 0.108
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0241 0.0145 0.0812
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0001 0.0005
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0102 0.0053 0.0292
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Brugia malayi jmjC domain containing protein 0.0022 0.0001 0.0004
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0028 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0091 0.0046 0.0043
Schistosoma mansoni glutamate receptor NMDA 0.0229 0.0138 0.0771
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0051 0.002 0.0109
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0142 0.008 0.0447
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0313 0.0193 0.108
Brugia malayi putative neuropeptide receptor NPR1 0.0313 0.0193 0.108
Echinococcus granulosus tm gpcr rhodopsin 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0005
Brugia malayi Eukaryotic aspartyl protease family protein 0.0034 0.0008 0.0045
Echinococcus granulosus somatostatin receptor 0.0313 0.0193 0.108
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Brugia malayi cytoplasmic intermediate filament protein 0.0042 0.0013 0.0075
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0134 0.0074 0.0417
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0218 0.013 0.2886
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0184 0.0108 0.3504
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Plasmodium falciparum glutathione reductase 0.0079 0.0038 0.0038
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0218 0.013 0.2886
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0004 0.0021
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0078 0.0037 0.0209
Loa Loa (eye worm) peptidase family M13 containing protein 0.0077 0.0037 0.0204
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0027 0.0004 0.0004
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0032 0.0007 0.0038
Loa Loa (eye worm) 6-phosphofructokinase 0.0064 0.0028 0.0158
Loa Loa (eye worm) phosphofructokinase 0.0064 0.0028 0.0158
Echinococcus multilocularis sex peptide receptor 0.0313 0.0193 0.108
Onchocerca volvulus 0.0078 0.0037 0.1196
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0046 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0026 0.0146
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.006 0.0026 0.0026
Echinococcus granulosus neuropeptide receptor A26 0.0587 0.0374 0.2096
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus 0.0313 0.0193 0.6305
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Chlamydia trachomatis endonuclease IV 0.019 0.0111 0.0108
Mycobacterium tuberculosis Conserved protein 0.0023 0.0001 0.0001
Echinococcus granulosus tachykinin peptides receptor 99D 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0036 0.001 0.0053
Echinococcus granulosus nmda type glutamate receptor 0.018 0.0105 0.0589
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0079 0.0038 0.0207
Brugia malayi sulfakinin receptor protein 0.0361 0.0225 0.126
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Brugia malayi Metabotropic glutamate receptor precursor. 0.1074 0.0697 0.3901
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0701 0.045 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0034 0.0008 0.0045
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0243 0.1355
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0023 0.0001 0.0001
Schistosoma mansoni protein kinase 0.0134 0.0074 0.0417
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0313 0.0193 0.108
Giardia lamblia Guanine phosphoribosyltransferase 0.0388 0.0243 0.1348
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0056 0.0023 0.0723
Brugia malayi mbt repeat family protein 0.0046 0.0017 0.0093
Loa Loa (eye worm) glutathione reductase 0.0079 0.0038 0.0212
Schistosoma mansoni purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0701 0.045 0.045
Echinococcus multilocularis serotonin receptor 0.0313 0.0193 0.108
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0023 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.003 0.0166
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0102 0.0053 0.0297
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0028 0.0004 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0027 0.0004 0.0004
Onchocerca volvulus Matrilysin homolog 0.0066 0.003 0.0941
Loa Loa (eye worm) hypothetical protein 0.0078 0.0037 0.0209
Loa Loa (eye worm) peptidase family M1 containing protein 0.0216 0.0129 0.0722
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0313 0.0193 0.108
Echinococcus multilocularis dna polymerase eta 0.0036 0.001 0.0053
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0079 0.0038 0.0212
Echinococcus granulosus g protein coupled receptor 0.0313 0.0193 0.108
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0732 0.0471 0.2635
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni folylpolyglutamate synthase 0.0153 0.0087 0.0489
Brugia malayi Receptor family ligand binding region containing protein 0.0318 0.0196 0.1099
Schistosoma mansoni 6-phosphofructokinase 0.0064 0.0028 0.0158
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0027 0.0004 0.0022
Treponema pallidum polypeptide deformylase (def) 0.0098 0.0051 0.0047
Echinococcus multilocularis glutamate receptor 2 0.0198 0.0117 0.0654
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0021 0.0000000000057596 0.000000000032248
Trypanosoma brucei unspecified product 0.0033 0.0008 0.0038
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.006 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0283 0.0174 0.0971
Loa Loa (eye worm) polyprenyl synthetase 0.2719 0.1786 1
Trypanosoma brucei Aminopeptidase M1, putative 0.0079 0.0038 0.0207
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0091 0.0046 0.0257
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0008 0.0045
Echinococcus multilocularis lamin dm0 0.0078 0.0037 0.0209
Echinococcus granulosus fmrfamide receptor 0.0313 0.0193 0.108
Brugia malayi hypothetical protein 0.0333 0.0206 0.1154
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0047 0.0017 0.0094
Brugia malayi Receptor family ligand binding region containing protein 0.0134 0.0074 0.0417
Echinococcus granulosus geminin 0.0215 0.0128 0.0718
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0001 0.0005
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0701 0.045 0.0446
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0201 0.0119 0.0667
Leishmania major hypothetical protein, conserved 0.0023 0.0001 0.0005
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0066 0.003 0.0166
Mycobacterium ulcerans epimerase 0.005 0.0019 0.0018
Brugia malayi Pre-SET motif family protein 0.0061 0.0026 0.0146
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0091 0.0046 0.0042
Brugia malayi dihydrofolate reductase family protein 0.0158 0.009 0.0506
Brugia malayi putative neuropeptide receptor 0.0313 0.0193 0.108
Trypanosoma cruzi trypanothione reductase, putative 0.0079 0.0038 0.0212
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0313 0.0193 0.108
Brugia malayi Associated with TFs and helicases family protein 0.0021 0.0000000000057596 0.000000000032248
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0021 0.0000000000057596 0.000000000032248
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0102 0.0053 0.1179
Onchocerca volvulus 0.0313 0.0193 0.6305
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0034 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0313 0.0193 0.108
Schistosoma mansoni hypothetical protein 0.0082 0.004 0.0226
Brugia malayi neuropeptide F receptor 0.0313 0.0193 0.108
Echinococcus multilocularis neuropeptides capa receptor 0.0313 0.0193 0.108
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0027 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0036 0.001 0.0054
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Plasmodium falciparum plasmepsin IX 0.0034 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0037 0.001 0.0232
Mycobacterium ulcerans aminopeptidase N PepN 0.0028 0.0004 0.0004
Onchocerca volvulus 0.0094 0.0048 0.1555
Toxoplasma gondii endonuclease IV APN 0.019 0.0111 0.0111
Echinococcus granulosus survival motor neuron protein 1 0.0333 0.0206 0.1154
Echinococcus multilocularis musashi 0.0078 0.0037 0.0209
Schistosoma mansoni tyrosine kinase 0.0134 0.0074 0.0417
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0156 0.0089 0.0499
Loa Loa (eye worm) calpain family protein 1 0.0063 0.0027 0.0153
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0142 0.008 0.0447
Echinococcus multilocularis calpain family protein 1, d 0.0044 0.0015 0.0084
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0026 0.0146
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0102 0.0053 0.0053
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0038 0.0011 0.006
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0017 0.0094
Brugia malayi beta-lactamase 0.0023 0.0001 0.0005
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0313 0.0193 0.108
Schistosoma mansoni ATP-binding cassette transporter 0.0132 0.0073 0.0409
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.5803 0.3828 0.7665
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0006 0.0036
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0074 0.0035 0.0035
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.0153 0.0087 0.0087
Mycobacterium tuberculosis Conserved protein 0.0023 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0001 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0002 0.0004
Brugia malayi CHD4 protein 0.0021 0.0000000000057596 0.000000000032248
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0032 0.0007 0.0037
Echinococcus granulosus tyrosine kinase 0.0134 0.0074 0.0417
Brugia malayi jmjC domain containing protein 0.0061 0.0026 0.0146
Echinococcus granulosus bloom syndrome protein 0.0034 0.0009 0.0048
Schistosoma mansoni adenoreceptor 0.0313 0.0193 0.108
Onchocerca volvulus 0.0313 0.0193 0.6305
Echinococcus multilocularis g protein coupled receptor 0.0313 0.0193 0.108
Schistosoma mansoni hypothetical protein 0.0184 0.0108 0.0603
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0313 0.0193 0.6305
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Schistosoma mansoni neprilysin-2 (M13 family) 0.0052 0.002 0.0114
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0017 0.0093
Echinococcus granulosus thioredoxin glutathione reductase 0.0079 0.0038 0.0212
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.019 0.0111 0.0222
Mycobacterium ulcerans endonuclease IV 0.019 0.0111 0.0111
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0266 0.0162 0.0905
Echinococcus multilocularis chromobox protein 1 0.0084 0.0041 0.0231
Loa Loa (eye worm) glutamate receptor 1 0.0132 0.0073 0.0409
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.0001 0.0005
Brugia malayi hypothetical protein 0.0034 0.0008 0.0045
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0701 0.045 0.2519
Mycobacterium leprae Probable imidazole glycerol-phosphate dehydratase HisB 0.373 0.2456 0.2456
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0008 0.0046
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0229 0.0138 0.0771
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0733 0.0471 0.0471
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0021 0.0000000000057596 0.000000000032248
Schistosoma mansoni opsin-like receptor 0.0313 0.0193 0.108
Onchocerca volvulus 0.0046 0.0017 0.0512
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Onchocerca volvulus 0.0051 0.002 0.0618
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0313 0.0193 0.108
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 1.5123 1 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.1308 0.0852 0.4771
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0701 0.045 0.09
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.0022 0.068
Loa Loa (eye worm) hypothetical protein 0.0078 0.0037 0.0209
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0218 0.013 0.0727
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0026 0.0146
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0153 0.0087 0.0489
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0037 0.0209
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0009 0.0048
Loa Loa (eye worm) hypothetical protein 0.0189 0.0111 0.062
Echinococcus multilocularis jumonji domain containing protein 0.0026 0.0003 0.0016
Brugia malayi hypothetical protein 0.0037 0.001 0.0059
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0313 0.0193 0.108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Plasmodium vivax glutathione reductase, putative 0.0079 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0127 0.007 0.039
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0266 0.0162 0.0905
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0047 0.0017 0.0094
Giardia lamblia Adenine phosphoribosyltransferase 0.0091 0.0046 0.0245
Brugia malayi larval opioid receptor 0.0313 0.0193 0.108
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0701 0.045 0.2516
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0211
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0027 0.0004 0.0022
Echinococcus granulosus atrial natriuretic peptide receptor 0.0134 0.0074 0.0417
Echinococcus multilocularis thyroid hormone receptor alpha 0.0161 0.0092 0.0518
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0054 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0115 0.0062 0.0349
Treponema pallidum adenine phosphoribosyltransferase 0.0091 0.0046 0.0042
Echinococcus multilocularis calpain A 0.0066 0.0029 0.0165
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0017 0.0094
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0079 0.0038 0.0212
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0313 0.0193 0.108
Brugia malayi beta-lactamase family protein 0.0023 0.0001 0.0005
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0732 0.0471 0.2635
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0313 0.0193 0.108
Loa Loa (eye worm) neuropeptide F receptor 0.0313 0.0193 0.108
Schistosoma mansoni intermediate filament proteins 0.0078 0.0037 0.0209
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0092 0.0518
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.1355
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0034 0.0008 0.0047
Loa Loa (eye worm) matrixin family protein 0.0147 0.0083 0.0465
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni histamine h1 receptor 0.0313 0.0193 0.108
Onchocerca volvulus Matrix metalloproteinase homolog 0.0147 0.0083 0.2693
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0074 0.0035 0.0195
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0153 0.0087 0.0489
Trypanosoma cruzi Aminopeptidase M1, putative 0.0079 0.0038 0.0212
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0002 0.0007
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.002 0.0114
Brugia malayi Peptidase family M13 containing protein 0.0104 0.0054 0.0305
Echinococcus granulosus adenine phosphoribosyltransferase 0.0091 0.0046 0.0257
Onchocerca volvulus 0.0034 0.0008 0.0232
Brugia malayi mbt repeat family protein 0.0046 0.0017 0.0093
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.001 0.0059
Echinococcus granulosus dihydrofolate reductase 0.0158 0.009 0.0506
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni endothelin-converting enzyme-related 0.0025 0.0003 0.0014
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0023 0.0129
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.006 0.0026 0.0139
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0056 0.0023 0.0129
Loa Loa (eye worm) hypothetical protein 0.0036 0.001 0.0054
Echinococcus granulosus jumonji domain containing protein 0.0026 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0094 0.0048 0.027
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.019 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0211
Echinococcus multilocularis dihydrofolate reductase 0.0158 0.009 0.0506
Echinococcus multilocularis neuropeptide FF receptor 2 0.0313 0.0193 0.108
Entamoeba histolytica aminopeptidase, putative 0.0079 0.0038 0.0842
Brugia malayi hypothetical protein 0.0313 0.0193 0.108
Schistosoma mansoni cathepsin D (A01 family) 0.0419 0.0263 0.1473
Schistosoma mansoni dihydrofolate reductase 0.0158 0.009 0.0506
Schistosoma mansoni biogenic amine receptor 0.0313 0.0193 0.108
Schistosoma mansoni hypothetical protein 0.0215 0.0128 0.0718
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0153 0.0087 0.2837
Mycobacterium ulcerans hypothetical protein 0.0023 0.0001 0.0001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0313 0.0193 0.6305
Mycobacterium ulcerans phosphoribosylamine--glycine ligase 0.0046 0.0016 0.0016
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0049 0.0018 0.0036
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0006 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.0001 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0004 0.0021
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.006 0.0026 0.0144
Echinococcus multilocularis survival motor neuron protein 1 0.0333 0.0206 0.1154
Echinococcus granulosus GPCR family 3 C terminal 0.0184 0.0108 0.0603
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0701 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0211
Onchocerca volvulus Poor gastrulation protein homolog 0.0184 0.0108 0.3504
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.005 0.0019 0.0106
Brugia malayi Dopamine receptor protein 1 0.0313 0.0193 0.108
Echinococcus multilocularis neuropeptides capa receptor 0.0313 0.0193 0.108
Loa Loa (eye worm) hypothetical protein 0.0051 0.002 0.011
Echinococcus multilocularis neutral sphingomyelinase 0.0034 0.0008 0.0047
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0313 0.0193 0.108
Echinococcus multilocularis allatostatin A receptor 0.0313 0.0193 0.108
Echinococcus granulosus g protein coupled receptor 0.0313 0.0193 0.108
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0313 0.0193 0.108
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0082 0.004 0.0226
Loa Loa (eye worm) hypothetical protein 0.0446 0.0281 0.1576
Brugia malayi Melatonin receptor type 1A 0.0313 0.0193 0.108
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0068 0.0031 0.0172
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0156 0.0089 0.0499
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0028 0.0004 0.0023
Brugia malayi Glutamate receptor 1 precursor 0.0132 0.0073 0.0409
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0081 0.0039 0.0078
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0017 0.0093
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0068 0.0031 0.0172
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0184 0.0108 0.0603
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0313 0.0193 0.108
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0047 0.0017 0.0094
Echinococcus multilocularis geminin 0.0215 0.0128 0.0718
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0037 0.0209
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0017 0.0093
Onchocerca volvulus 0.0094 0.0048 0.1542
Schistosoma mansoni chromobox protein 0.0084 0.0041 0.0231
Echinococcus granulosus metabotropic glutamate receptor 2 0.0889 0.0575 0.3218
Brugia malayi metabotropic glutamate receptor type 2 0.0553 0.0352 0.197
Echinococcus multilocularis fmrfamide receptor 0.0313 0.0193 0.108
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0004 0.0016
Chlamydia trachomatis dihydrofolate reductase 0.0158 0.009 0.0087
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0021 0.0119
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0034 0.0008 0.0046
Loa Loa (eye worm) hypothetical protein 0.0357 0.0222 0.1244
Loa Loa (eye worm) hypothetical protein 0.0066 0.0029 0.0164
Loa Loa (eye worm) zinc metallopeptidase 4 0.0025 0.0003 0.0014
Mycobacterium tuberculosis Probable dehydrogenase 0.0179 0.0105 0.0209
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0027 0.0004 0.0004
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0243 0.1359
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0047 0.0017 0.0089
Loa Loa (eye worm) TYRA-2 protein 0.0313 0.0193 0.108
Entamoeba histolytica hypothetical protein 0.0037 0.001 0.0232
Trypanosoma cruzi hypothetical protein, conserved 0.0102 0.0053 0.0297
Giardia lamblia Rab geranylgeranyltransferase 0.0357 0.0222 0.1233
Echinococcus granulosus rhodopsin orphan GPCR 0.0313 0.0193 0.108
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.008 0.0039 0.0216
Echinococcus granulosus 7TM GPCR rhodopsin 0.0313 0.0193 0.108
Echinococcus granulosus orexin receptor type 2 0.0313 0.0193 0.108
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0092 0.0518
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0357 0.0222 0.1244
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0028 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0027 0.0004 0.0021
Brugia malayi hypothetical protein 0.0361 0.0225 0.126
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0068 0.0031 0.0172
Plasmodium falciparum plasmepsin X 0.0034 0.0008 0.0008
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0733 0.0471 0.0468
Loa Loa (eye worm) hypothetical protein 0.0134 0.0074 0.0417
Schistosoma mansoni neuropeptide receptor 0.0313 0.0193 0.108
Brugia malayi G protein-coupled receptor F59B2.13 0.0313 0.0193 0.108
Plasmodium falciparum plasmepsin III 0.0034 0.0008 0.0008
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0041 0.0231
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0017 0.0093
Echinococcus granulosus glutamate receptor 2 0.0266 0.0162 0.0905

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = -7.745 Inhibition of binding of [125I]-All at the angiotensin II type 1 receptor (AT1 receptor) in rat liver membranes ChEMBL. No reference
Log Ki (binding) = 7.745 Inhibition of binding of [125I]-All at the angiotensin II type 1 receptor (AT1 receptor) in rat liver membranes ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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