Detailed information for compound 290612

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 413.063 | Formula: C6H10NO14P3------
  • H donors: 3 H acceptors: 11 LogP: -10.02 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: NC1C(OP(=O)([O-])[O-])C(OP(=O)([O-])[O-])C(C(C1O)OP(=O)([O-])[O-])O
  • InChi: 1S/C6H16NO14P3/c7-1-2(8)5(20-23(13,14)15)3(9)6(21-24(16,17)18)4(1)19-22(10,11)12/h1-6,8-9H,7H2,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/p-6
  • InChiKey: RHUZQIJSAKZPDO-UHFFFAOYSA-H  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0335 0.214 0.5027
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0124 0.0124
Echinococcus granulosus death domain containing protein 0.0015 0.0008 0.0007
Brugia malayi Thioredoxin reductase 0.0189 0.1169 0.2745
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus multilocularis glutamate synthase 0.0017 0.0027 0.0027
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0031 0.0118 0.0296
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0767 0.1578
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0035 0.0142 0.0441
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.0027 0.0134
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0014 0.0003 0.0007
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0038 0.0161 0.1374
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0 0.0002
Schistosoma mansoni multidrug resistance protein 0.0056 0.0286 0.0286
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0124 0.0291
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.006
Onchocerca volvulus 0.0132 0.0791 0.1623
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0124 0.0124
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0124 0.0124
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0251 0.1581 0.3714
Brugia malayi nuclear receptor NHR-88 0.0015 0.0012 0.0026
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0017 0.0027 0.0227
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0124 0.0124
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0124 0.0124
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0027 0.0027
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0035 0.0142 0.0661
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0014 0.0003 0.0007
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.0632 0.1393
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0014 0.0003 0.0007
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0646 0.1517
Leishmania major p-glycoprotein e 0.0056 0.0286 0.1429
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0191 0.1177 0.2602
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.0027 0.0055
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0369 0.0368
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0124 0.0124
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0142 0.0709
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0111 0.0647 0.3233
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0086 0.0484 0.0484
Brugia malayi Associated with TFs and helicases family protein 0.0038 0.0161 0.0377
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0012 0.0011
Brugia malayi PHD-finger family protein 0.0029 0.0104 0.0244
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0205 0.1025
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0242 0.0499
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0741 0.074
Schistosoma mansoni ap endonuclease 0.0069 0.0367 0.0367
Echinococcus multilocularis peregrin 0.0023 0.0063 0.0062
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0124 0.0291
Mycobacterium tuberculosis Conserved protein 0.0108 0.0632 0.1393
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Schistosoma mansoni aldehyde dehydrogenase 0.0191 0.1177 0.1177
Trypanosoma cruzi NADH dehydrogenase, putative 0.0017 0.0027 0.0134
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0069 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0056 0.0283 0.0664
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.006
Trichomonas vaginalis Heterochromatin protein, putative 0.0038 0.0161 0.0331
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0048 0.0231 0.0543
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0161 0.05
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0258 0.0604
Schistosoma mansoni aldehyde dehydrogenase 0.0191 0.1177 0.1177
Echinococcus multilocularis chromobox protein 1 0.023 0.1437 0.1437
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0017 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Leishmania major cAMP-specific phosphodiesterase, putative 0.0013 0 0.0002
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0017 0.0027 0.0084
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.048 0.31 1
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0517 0.1064
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.011 0.1843
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0481 0.1476
Schistosoma mansoni inositol monophosphatase 0.0035 0.0142 0.0142
Loa Loa (eye worm) multidrug resistance-associated protein 0.0044 0.0202 0.0474
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0152 0.0471
Schistosoma mansoni cript-related 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.002 0.0036
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0069 0.0367 0.0367
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.011 0.0644 0.0643
Brugia malayi Augmenter of liver regeneration 0.0034 0.0139 0.0326
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0027 0.0134
Schistosoma mansoni hypothetical protein 0.0086 0.0484 0.0484
Trypanosoma brucei NADH dehydrogenase 0.0017 0.0027 0.0134
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0065 0.0201
Plasmodium falciparum phd finger protein, putative 0.002 0.0046 0.0393
Schistosoma mansoni nuclear receptor 0.0015 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0038 0.0161 0.0161
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0124 0.0291
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0048 0.0047
Echinococcus multilocularis ryanodine receptor 44f 0.0094 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 0.3027
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0017 0.0027 0.0027
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Plasmodium falciparum DNase I-like protein, putative 0.0014 0.0003 0.0025
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0024 0.0199
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0313 0.0734
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0646 0.413
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0138 0.0831 0.1706
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0161 0.1374
Schistosoma mansoni sulfide quinone reductase 0.0017 0.0027 0.0027
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0017 0.0027 0.0134
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0142 0.0292
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0152 0.0757
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0161 0.0331
Brugia malayi beta-lactamase family protein 0.0108 0.0632 0.1484
Schistosoma mansoni zinc finger protein 0.0016 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0205 0.0421
Trypanosoma cruzi lanosterol synthase, putative 0.019 0.1176 0.5876
Brugia malayi nuclear hormone receptor 0.0032 0.0124 0.0291
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0124 0.0249
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.0632 0.1393
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0152 0.0151
Brugia malayi Protein kinase domain containing protein 0.0015 0.0011 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0124 0.0291
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0065 0.0136
Trichomonas vaginalis mercuric reductase, putative 0.0066 0.0347 0.0715
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0124 0.0124
Brugia malayi nuclear receptor NHR-88 0.0032 0.0124 0.0291
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0008 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0646 0.133
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0013 0 0.0002
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0646 0.2006
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0029 0.0029
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0152 0.0757
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0017 0.0027 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Echinococcus granulosus survival motor neuron protein 1 0.0499 0.3229 0.3229
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0284 0.142
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0038 0.0161 0.0161
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0048 0.0405
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0108 0.0108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0008 0.0017
Schistosoma mansoni smad 0.0017 0.0027 0.0027
Schistosoma mansoni intermediate filament proteins 0.0052 0.0258 0.0257
Loa Loa (eye worm) hypothetical protein 0.0052 0.0258 0.0604
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0015 0.0013 0.0061
Brugia malayi MH2 domain containing protein 0.0017 0.0027 0.0063
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0017 0.0027 0.0052
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0077 0.0181
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0056 0.0286 0.1429
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.0632 0.1393
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0012 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0012 0.0011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0152 0.0151
Schistosoma mansoni coup transcription factor 0.0032 0.0124 0.0124
Entamoeba histolytica ATP-binding cassette protein, putative 0.0056 0.0286 0.0888
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0646 0.133
Loa Loa (eye worm) hypothetical protein 0.0499 0.3229 0.7585
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0107 0.0251
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0205 0.1025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0377
Schistosoma mansoni netrin receptor unc5 0.0015 0.0008 0.0007
Loa Loa (eye worm) DR-78 0.0015 0.0012 0.0026
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 0.3027
Treponema pallidum thioredoxin reductase (trxB) 0.0017 0.0027 0.0073
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0056 0.0286 0.1429
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0646 0.1517
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0013 0 0.0001
Schistosoma mansoni Smad4 0.0017 0.0027 0.0027
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0056 0.0286 0.0671
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0113 0.0659 0.0659
Echinococcus multilocularis cpg binding protein 0.0059 0.0304 0.0304
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0369 0.2282
Onchocerca volvulus 0.0108 0.0632 0.1295
Entamoeba histolytica ATP-binding cassette protein, putative 0.0056 0.0286 0.0888
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0124 0.0291
Leishmania major endonuclease/exonuclease protein-like protein 0.0014 0.0003 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0124 0.0124
Toxoplasma gondii hypothetical protein 0.0335 0.214 1
Schistosoma mansoni cpg binding protein 0.0059 0.0304 0.0304
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0139 0.0139
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0901 0.4499
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.048 0.31 0.6863
Echinococcus granulosus Ankyrin 0.0015 0.0008 0.0008
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0284 0.142
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0111
Loa Loa (eye worm) hypothetical protein 0.0108 0.0632 0.1484
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 1
Echinococcus multilocularis GPCR, family 2 0.0086 0.0484 0.0484
Schistosoma mansoni lamin 0.0052 0.0258 0.0257
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0012 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0017 0.0027 0.0052
Schistosoma mansoni hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis dnaJ subfamily B 0.04 0.2571 0.257
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0012 0.0011
Leishmania major hypothetical protein, conserved 0.0034 0.0139 0.0696
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0066 0.0347 0.2138
Echinococcus granulosus synaptojanin 1 0.0014 0.0003 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0347 0.1733
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0066 0.0347 0.7063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0066 0.0347 0.2138
Brugia malayi MH1 domain containing protein 0.0017 0.0027 0.0063
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0124 0.0124
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.1177 0.7668
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0008 0.0007
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.002 0.0046 0.0046
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0017 0.0027 0.0134
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0069 0.0367 0.114
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.011 0.0226
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0901 0.4499
Loa Loa (eye worm) RNA binding protein 0.0125 0.0741 0.1739
Entamoeba histolytica ATP-binding cassette protein, putative 0.0056 0.0286 0.0888
Schistosoma mansoni neutral sphingomyelinase 0.0014 0.0003 0.0003
Brugia malayi Inositol-1 0.0035 0.0142 0.0333
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0065 0.0259
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Brugia malayi MH2 domain containing protein 0.0017 0.0027 0.0063
Echinococcus granulosus histone lysine methyltransferase setb 0.0113 0.0659 0.0659
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.011 0.0936
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.011 0.1843
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0113 0.0659 0.0659
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0054 0.0271 0.0635
Plasmodium vivax exodeoxyribonuclease III, putative 0.0014 0.0003 0.0025
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0012 0.0011
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0646 0.0646
Plasmodium vivax thioredoxin reductase, putative 0.0189 0.1169 1
Trypanosoma brucei p-glycoprotein 0.0056 0.0286 0.1429
Entamoeba histolytica hypothetical protein 0.0069 0.0369 0.1146
Echinococcus multilocularis Chromo domain 0.0038 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0379
Leishmania major hypothetical protein, conserved 0.0108 0.0632 0.3156
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0023 0.0023
Schistosoma mansoni disulfide oxidoreductase 0.0017 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.0108 0.0632 0.4035
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0008 0.0017
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0024 0.0023
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0017 0.0027 0.0027
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0014 0.0003 0.0016
Onchocerca volvulus 0.0108 0.0632 0.1295
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0024 0.0055
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0152 0.0757
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0017 0.0027 0.0055
Brugia malayi hypothetical protein 0.0499 0.3229 0.7585
Plasmodium falciparum glutathione reductase 0.0189 0.1169 1
Treponema pallidum oxidoreductase 0.0017 0.0027 0.0073
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0142 0.0709
Mycobacterium tuberculosis Conserved protein 0.0108 0.0632 0.1393
Echinococcus granulosus PHD finger protein rhinoceros 0.002 0.0046 0.0046
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Plasmodium vivax hypothetical protein, conserved 0.002 0.0046 0.0393
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0152 0.0312
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.0632 0.3156
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0097 0.0555 0.1302
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0069 0.0367 0.0862
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0069 0.0367 0.3139
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0065 0.0259
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0017 0.0027 0.0006
Echinococcus granulosus neuropeptide s receptor 0.0462 0.2981 0.2981
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0065 0.0259
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Loa Loa (eye worm) hypothetical protein 0.0036 0.0152 0.0355
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0405 0.0405
Echinococcus granulosus Chromobox protein 3 0.0038 0.0161 0.0161
Trypanosoma brucei protein kinase, putative 0.0056 0.0284 0.142
Leishmania major hypothetical protein, conserved 0.0016 0.0017 0.0086
Onchocerca volvulus 0.0032 0.0124 0.0249
Entamoeba histolytica hypothetical protein 0.0069 0.0369 0.1146
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0131 0.0784 0.1841
Entamoeba histolytica ATP-binding cassette protein, putative 0.0056 0.0286 0.0888
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0124 0.0291
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0086 0.0484 0.0484
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0012 0.0011
Schistosoma mansoni zinc finger protein 0.0023 0.0067 0.0067
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0014 0.0003 0.0003
Schistosoma mansoni multidrug resistance protein 0.0056 0.0286 0.0286
Trypanosoma cruzi hypothetical protein 0.0043 0.0199 0.0994
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0014 0.0003 0.001
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0014 0.0003 0.0007
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0017 0.0027 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0284 0.0586
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0014 0.0003 0.0007
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.011 0.0936
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0481 0.2244
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0151
Schistosoma mansoni glutamate synthase 0.0017 0.0027 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0284 0.0586
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0432 0.278 0.6153
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0017 0.0027 0.0084
Echinococcus granulosus tar DNA binding protein 0.0125 0.0741 0.074
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0017 0.0027 0.0027
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0017 0.0027 0.0227
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0517 0.1064
Mycobacterium leprae conserved hypothetical protein 0.0108 0.0632 0.1969
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0124 0.0291
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0124 0.0124
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0027 0.0027
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0541 0.2528
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Schistosoma mansoni hypothetical protein 0.0021 0.0054 0.0054
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0152 0.0355
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0139 0.0649
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0243 0.1528 0.3378
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0108
Trypanosoma cruzi ISWI complex protein 0.0016 0.0017 0.0086
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 0.4109
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0097 0.0226
Giardia lamblia Glutamate synthase 0.0017 0.0027 0.0082
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0016
Echinococcus multilocularis smad 0.0017 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0541 0.0541
Plasmodium falciparum thioredoxin reductase 0.0189 0.1169 1
Loa Loa (eye worm) hypothetical protein 0.0524 0.339 0.7963
Trypanosoma cruzi mitochondrial protein 99, putative 0.0014 0.0003 0.0016
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0432 0.278 0.6153
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0107 0.0916
Loa Loa (eye worm) hypothetical protein 0.0545 0.353 0.8292
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Leishmania major lanosterol synthase, putative 0.019 0.1176 0.5876
Echinococcus multilocularis Ankyrin 0.0015 0.0008 0.0008
Plasmodium vivax heterochromatin protein 1, putative 0.0038 0.0161 0.1374
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Trichomonas vaginalis ap endonuclease, putative 0.0069 0.0367 0.0756
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 0.1484
Brugia malayi Probable ClpP-like protease 0.0086 0.0481 0.1128
Echinococcus multilocularis neutral sphingomyelinase 0.0014 0.0003 0.0003
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0014 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.04 0.2571 0.257
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0347 0.1733
Trypanosoma cruzi multidrug resistance protein E, putative 0.0056 0.0286 0.1429
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0251 0.1581 0.1581
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0124 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0124 0.0291
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0021 0.0048 0.0048
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0646 0.0646
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0632 0.0632
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0066 0.0347 0.2967
Loa Loa (eye worm) hypothetical protein 0.0086 0.0484 0.1136
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0124 0.0124
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0056 0.0286 0.1429
Mycobacterium ulcerans hypothetical protein 0.0166 0.1013 0.657
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0012 0.0026
Trypanosoma brucei trypanothione reductase 0.0189 0.1169 0.5838
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0065 0.0151
Schistosoma mansoni transcription factor LCR-F1 0.0069 0.0369 0.0369
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0432 0.278 0.6153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Echinococcus multilocularis lamin 0.0052 0.0258 0.0257
Toxoplasma gondii histone lysine methyltransferase SET1 0.0108 0.0632 0.295
Echinococcus multilocularis musashi 0.0052 0.0258 0.0257
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0124 0.0291
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0014 0.0003 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.0027 0.0055
Plasmodium falciparum glutathione reductase 0.0066 0.0347 0.2967
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0017 0.0027 0.0124
Brugia malayi SET domain containing protein 0.0042 0.0192 0.0449
Brugia malayi hypothetical protein 0.0021 0.0048 0.0111
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0065 0.0259
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0014 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0038 0.0161 0.05
Leishmania major NADH dehydrogenase, putative 0.0017 0.0027 0.0134
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0124 0.0291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0199 0.0409
Schistosoma mansoni polycystin 1-related 0.0021 0.0048 0.0047
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.0632 0.0632
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.0632 0.1393
Echinococcus multilocularis chromobox protein 2 0.0038 0.0161 0.0161
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Schistosoma mansoni hypothetical protein 0.0021 0.0048 0.0047
Trypanosoma cruzi NADH dehydrogenase, putative 0.0017 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0377
Toxoplasma gondii NADPH-glutathione reductase 0.0066 0.0347 0.162
Brugia malayi glutamate synthase 0.0017 0.0027 0.0062
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0124 0.0249
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0481 0.048
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0069 0.0367 0.1139
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0066 0.0347 0.2967
Echinococcus granulosus stromal cell derived factor 2 0.0021 0.0048 0.0048
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0017 0.0027 0.0052
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Mycobacterium leprae Probable lipase LipE 0.0108 0.0632 0.1969
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Brugia malayi nuclear receptor NHR-67 0.0015 0.0012 0.0026
Toxoplasma gondii 6-phosphofructokinase 0.003 0.011 0.0511
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0024 0.0023
Echinococcus multilocularis zinc finger protein 0.0023 0.0067 0.0067
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0632 0.5405
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0017 0.0027 0.0027
Trichomonas vaginalis set domain proteins, putative 0.0744 0.4857 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0031 0.0118 0.0254
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0369 0.1841
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0139 0.0139
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0161 0.0331
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0646 0.133
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0251 0.1581 0.3714
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0045 0.0045
Mycobacterium tuberculosis Probable reductase 0.0432 0.278 0.6153
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0022 0.0102
Entamoeba histolytica hypothetical protein 0.0038 0.0161 0.05
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0481 0.2244
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0065 0.0259
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0017 0.0027 0.0055
Leishmania major hypothetical protein, conserved 0.0017 0.0027 0.0134
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0102 0.0588 0.0588
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0498 0.322 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0066 0.0347 0.162
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0107 0.0324
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0066 0.0347 0.2967
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0741 0.074
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0017 0.0027 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0151
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0012 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0284 0.0586
Onchocerca volvulus 0.0744 0.4858 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Brugia malayi hypothetical protein 0.0015 0.0012 0.0026
Echinococcus granulosus chromobox protein 1 0.023 0.1437 0.1437
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0191 0.1177 0.5881
Plasmodium falciparum ferrodoxin reductase-like protein 0.0017 0.0027 0.0227
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0124 0.0124
Schistosoma mansoni hypothetical protein 0.0186 0.1148 0.1148
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0481 0.048
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0008 0.0007
Echinococcus granulosus peregrin 0.0023 0.0063 0.0062
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.0632 0.1484
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0481 1
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0014 0.0003 0.0007
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0066 0.0347 0.0347
Echinococcus multilocularis thioredoxin glutathione reductase 0.019 0.1172 0.1172
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.048 0.31 0.6863
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0113 0.0659 0.0659
Echinococcus multilocularis multidrug resistance associated protein 1 0.0056 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.004 0.0177 0.0415
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0646 0.0646
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0014 0.0003 0.0007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0003 0.0016
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0013 0 0.0002
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0065 0.0259
Loa Loa (eye worm) hypothetical protein 0.0074 0.0401 0.0941
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0741 0.1739
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.006
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0017 0.0027 0.0006
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.011 0.0341
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0646 0.133
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0108 0.0632 0.1484
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0 0.0002
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0017 0.0027 0.0006
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0017 0.0027 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0901 0.4499
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0369 0.081
Echinococcus multilocularis inositol monophosphatase 1 0.0035 0.0142 0.0142
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0017 0.0027 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0038 0.0161 0.075
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0012 0.0026
Trypanosoma cruzi lanosterol synthase, putative 0.019 0.1176 0.5876
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0142 0.0292
Plasmodium vivax SET domain protein, putative 0.0095 0.0541 0.4629
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.011 0.0936
Brugia malayi Uncoordinated protein 44 0.0015 0.0008 0.0017
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0646 0.3227
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0243 0.1528 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0068 0.0067
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0251 0.1581 0.1581
Brugia malayi jmjC domain containing protein 0.0067 0.0354 0.083
Trichomonas vaginalis ap endonuclease, putative 0.0069 0.0367 0.0756
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0511 0.051
Treponema pallidum fructose-bisphosphate aldolase 0.0498 0.322 1
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0054 0.0126
Echinococcus multilocularis deoxyribonuclease 1 2 0.0014 0.0003 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0251 0.1581 0.1581
Leishmania major hypothetical protein, conserved 0.0017 0.0027 0.0134
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.011 0.0644 0.0643
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0012 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.011 0.0226
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Echinococcus multilocularis synaptojanin 1 0.0014 0.0003 0.0003
Echinococcus granulosus multidrug resistance associated protein 7 0.0056 0.0286 0.0286
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0124 0.0124
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0481 0.048
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0017 0.0027 0.0124
Loa Loa (eye worm) glutathione reductase 0.0189 0.1169 0.2745
Schistosoma mansoni survival motor neuron protein 0.0102 0.0588 0.0588
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0161 0.0331
Giardia lamblia Multidrug resistance-associated protein 1 0.0056 0.0283 0.0878
Brugia malayi nuclear receptor RXR 0.0015 0.0012 0.0026
Brugia malayi conserved hypotetical protein 0.0015 0.0012 0.0026
Leishmania major pantothenate kinase subunit, putative 0.0015 0.001 0.0048
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0043 0.0195 0.0194
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.006
Schistosoma mansoni lipoxygenase 0.0123 0.0728 0.0727
Echinococcus granulosus multidrug resistance associated protein 4 0.0043 0.0199 0.0199
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0111 0.0647 0.3233
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0038 0.0161 0.1374
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0124 0.0124
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Entamoeba histolytica hypothetical protein 0.0056 0.0286 0.0888
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Brugia malayi CXXC zinc finger family protein 0.0054 0.0271 0.0635
Loa Loa (eye worm) CHromoDomain protein family member 0.0043 0.0195 0.0456
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0097 0.0555 0.0554
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.0027 0.0134
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Echinococcus granulosus geminin 0.0933 0.6115 0.6115
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0017 0.0027 0.0062
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.011 0.0936
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0029 0.0029
Brugia malayi Doublecortin family protein 0.0021 0.0048 0.0111
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.019 0.0446
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0097 0.0226
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0124 0.0124
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0127 0.0752 0.166
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0205 0.1025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0242 0.0499
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0066 0.0347 0.1733
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0066 0.0347 0.2967
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0012 0.0011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0086 0.0484 0.1136
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0189 0.1169 0.2583
Giardia lamblia Multidrug resistance-associated protein 1 0.0056 0.0286 0.0887
Brugia malayi phosphofructokinase 0.0111 0.0646 0.1517
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0498 0.322 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0152 0.0151
Brugia malayi tailless protein 0.0015 0.0012 0.0026
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0017 0.0027 0.0124
Echinococcus granulosus ryanodine receptor 44f 0.0073 0.0396 0.0395
Schistosoma mansoni zinc finger protein 0.0015 0.0012 0.0011
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0014 0.0003 0.001
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0014 0.0003 0.0025
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0065 0.0324
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0017 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0377
Echinococcus granulosus traf and tnf receptor associated protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0062
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0014 0.0003 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0831 0.1712
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0024 0.0055
Echinococcus granulosus lamin 0.0052 0.0258 0.0257
Loa Loa (eye worm) histone methyltransferase 0.002 0.0045 0.0106
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0632 0.1301
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0008 0.0009
Echinococcus multilocularis Smad4 0.0017 0.0027 0.0027
Brugia malayi steroid hormone receptor 0.0032 0.0124 0.0291
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0284 0.0284
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.0027 0.0134
Schistosoma mansoni bromodomain containing protein 0.0069 0.037 0.0369
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0284 0.1327
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0088 0.0087
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0152 0.047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0097 0.0555 0.1302
Brugia malayi nuclear hormone receptor 0.0015 0.0012 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0066 0.0347 0.1733
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.011 0.0226
Loa Loa (eye worm) RecQ helicase 0.0025 0.0077 0.0181
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0088 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Echinococcus granulosus multidrug resistance associated protein 1 0.0056 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0014 0.0003 0.0025
Echinococcus multilocularis lamin dm0 0.0052 0.0258 0.0257
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0069 0.0367 0.0367
Onchocerca volvulus 0.0023 0.0065 0.0127
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0632 0.1301
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0152 0.0312
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0048 0.0047
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0014 0.0003 0.0025
Echinococcus multilocularis multidrug resistance associated protein 7 0.0056 0.0286 0.0286
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0013 0 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0632 0.3156
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0118 0.0697 0.0696
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0347 0.7057
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0014 0.0003 0.0025
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.011 0.0511
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0065 0.0201
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0038 0.0161 0.075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0242 0.0499
Brugia malayi CHD4 protein 0.0043 0.0195 0.0456
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Toxoplasma gondii selenide, water dikinase 0.0017 0.0027 0.0124
Leishmania major hypothetical protein, conserved 0.0013 0 0.0002
Schistosoma mansoni hypothetical protein 0.0086 0.0484 0.0484
Loa Loa (eye worm) inositol-1 0.0035 0.0142 0.0333
Schistosoma mansoni hypothetical protein 0.0086 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.0048 0.0227 0.0532
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0741 0.074
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0035 0.0147 0.0146
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0139 0.1189
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0038 0.0161 0.0377
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0646 0.1517
Loa Loa (eye worm) hypothetical protein 0.0335 0.214 0.5027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0347 0.1733
Loa Loa (eye worm) hypothetical protein 0.0025 0.0078 0.0183
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0024 0.0055
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0142 0.0709
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Trypanosoma brucei lanosterol synthase 0.019 0.1176 0.5876
Onchocerca volvulus 0.0052 0.0258 0.0524
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0057 0.0486
Echinococcus multilocularis ryanodine receptor 44f 0.0073 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Mycobacterium ulcerans glutamate synthase subunit beta 0.0017 0.0027 0.0006
Toxoplasma gondii hypothetical protein 0.0051 0.0248 0.1159
Loa Loa (eye worm) helicase 0.0038 0.0161 0.0377
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0315 0.2002 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0111
Loa Loa (eye worm) hypothetical protein 0.0113 0.0659 0.1548
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0124 0.0124
Echinococcus granulosus GPCR family 2 0.0086 0.0484 0.0484
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0242 0.0499
Schistosoma mansoni loxhd1 0.0021 0.0048 0.0047
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0014 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0012 0.0011
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0017 0.0027 0.0084
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.0027 0.0055
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0078 0.0078
Schistosoma mansoni chromobox protein 0.0038 0.0161 0.0161
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0034 0.0078
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0038 0.0161 0.0161
Loa Loa (eye worm) beta-lactamase 0.0108 0.0632 0.1484
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0014 0.0003 0.0007
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0069 0.0367 0.3139
Echinococcus granulosus Chromo domain 0.0038 0.0161 0.0161
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0845 0.5526 0.5525
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Loa Loa (eye worm) hypothetical protein 0.0032 0.0124 0.0291
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0035 0.0142 0.2536
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0152 0.0312
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0107 0.0916
Brugia malayi multidrug resistance related protein 1 0.0056 0.0286 0.0671
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0014 0.0003 0.0007
Brugia malayi Pre-SET motif family protein 0.0654 0.4257 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0272 0.1721 0.4042
Trichomonas vaginalis Phospholipase C precursor, putative 0.0014 0.0003 0.0007
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0012 0.0026
Giardia lamblia NADH oxidase lateral transfer candidate 0.0066 0.0347 0.1077
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0284 0.0623
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0284 0.0284
Leishmania major ABC-thiol transporter 0.0056 0.0286 0.1429
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0065 0.0123
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0284 0.0284
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0012 0.0011
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0014 0.0003 0.0025
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0027 0.0027
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0003 0.0025
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0284 0.0838
Leishmania major hypothetical protein, conserved 0.0013 0 0.0002
Brugia malayi MIR domain containing protein 0.0021 0.0048 0.0112
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0038 0.0161 0.075
Echinococcus granulosus glutamate synthase 0.0017 0.0027 0.0027
Schistosoma mansoni multidrug resistance protein 0.0056 0.0286 0.0286
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0056 0.0286 0.1429
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0152 0.0151
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0069 0.0367 0.7501
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0065 0.0324
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0067 0.0354 0.0353
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0632 0.0632
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0014 0.0003 0.0016
Trypanosoma cruzi ISWI complex protein 0.0016 0.0017 0.0086
Leishmania major hypothetical protein, conserved 0.0075 0.0412 0.2056
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0632 0.1301
Mycobacterium tuberculosis Probable dehydrogenase 0.0432 0.278 0.6153
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0481 0.4109
Echinococcus multilocularis stromal cell derived factor 2 0.0021 0.0048 0.0048
Mycobacterium ulcerans hypothetical protein 0.0017 0.0027 0.0006
Leishmania major mitochondrial DNA polymerase beta 0.0315 0.2002 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Schistosoma mansoni hypothetical protein 0.0933 0.6115 0.6115
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.0632 0.1393
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0258 0.0604
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0069 0.0367 0.1834
Schistosoma mansoni carbon catabolite repressor protein 0.0014 0.0003 0.0003
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0139 0.0696
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0012 0.0026
Echinococcus granulosus thioredoxin glutathione reductase 0.019 0.1172 0.1172
Entamoeba histolytica hypothetical protein 0.0069 0.0369 0.1146
Trichomonas vaginalis chromobox protein, putative 0.023 0.1437 0.2959
Echinococcus multilocularis neuropeptide receptor A26 0.0462 0.2981 0.2981
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0108 0.0108
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0124 0.0124
Echinococcus multilocularis RUN 0.0021 0.0048 0.0047
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0012 0.0017
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0284 0.0882
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0017 0.0027 0.0062
Brugia malayi chromobox protein homolog 3 0.0129 0.0767 0.18
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0014 0.0003 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0048 0.0231 0.0543
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0123 0.0728 0.0727
Toxoplasma gondii ABC1 family protein 0.0108 0.0632 0.2951
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.016 0.016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0432 0.278 0.8958
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0014 0.0003 0.001
Leishmania major hypothetical protein, conserved 0.0017 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0186 0.1148 0.2697
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trypanosoma brucei multidrug resistance protein E 0.0056 0.0286 0.1429
Trypanosoma brucei RNA editing exonuclease 2 0.0014 0.0003 0.0016
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.011 0.034
Giardia lamblia Inositol 5-phosphatase 4 0.0014 0.0003 0.0009
Echinococcus multilocularis jumonji domain containing protein 0.0028 0.0099 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0132 0.0791 0.0791
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0097 0.0555 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0767 0.1578
Onchocerca volvulus 0.0052 0.0258 0.0524
Onchocerca volvulus 0.0102 0.0588 0.1205
Mycobacterium ulcerans lipase LipD 0.0108 0.0632 0.4035
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0038 0.0161 0.0161
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.011 0.0644 0.0643
Entamoeba histolytica ABC transporter, putative 0.0056 0.0286 0.0888
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0242 0.0499
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.1177 0.7668
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0646 0.2015
Echinococcus granulosus zinc finger protein 0.0023 0.0067 0.0067
Giardia lamblia Thioredoxin reductase 0.0017 0.0027 0.0082
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0012 0.0026
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0014 0.0003 0.0025
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0345 0.0345
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0124 0.0124
Schistosoma mansoni ap endonuclease 0.0069 0.0367 0.0367
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.001
Trichomonas vaginalis glutamate synthase, putative 0.0017 0.0027 0.0055
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0347 0.7057
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0205 0.1025
Loa Loa (eye worm) hypothetical protein 0.0056 0.0286 0.0671
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0048 0.0111
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus multilocularis multidrug resistance associated protein 4 0.0043 0.0199 0.0199
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0017 0.0027 0.0134
Brugia malayi 6-phosphofructokinase 0.0111 0.0649 0.1524
Schistosoma mansoni nuclear receptor 0.0015 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0108 0.0632 0.1484
Onchocerca volvulus 0.0015 0.0012 0.0018
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0017 0.0027 0.0134
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0284 0.0623
Brugia malayi Cytochrome P450 family protein 0.0029 0.0107 0.0251
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0152 0.0151
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.027 0.1346
Loa Loa (eye worm) transcription factor SMAD2 0.0256 0.1612 0.3786
Loa Loa (eye worm) hypothetical protein 0.0126 0.0748 0.1756
Toxoplasma gondii aldehyde dehydrogenase 0.0191 0.1177 0.55
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.011 0.0226
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.0632 0.4035
Brugia malayi beta-lactamase family protein 0.0108 0.0632 0.1484
Treponema pallidum exodeoxyribonuclease (exoA) 0.0069 0.0367 0.1131
Mycobacterium tuberculosis Conserved protein 0.0108 0.0632 0.1393
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0 0.0002
Trypanosoma brucei ISWI complex protein 0.0016 0.0017 0.0086
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0017
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0646 0.3227
Echinococcus granulosus RUN 0.0021 0.0048 0.0047
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Onchocerca volvulus 0.0054 0.0271 0.0551
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Giardia lamblia PHD finger protein 15 0.002 0.0046 0.0143
Loa Loa (eye worm) MIR domain-containing protein 0.0021 0.0048 0.0112
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0124 0.0124
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0017 0.0027 0.0027
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0046 0.0215
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0347 0.1733
Schistosoma mansoni glutamate synthase 0.0017 0.0027 0.0027
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0027 0.0027
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0014 0.0003 0.0016
Echinococcus multilocularis traf and tnf receptor associated protein 0.0014 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0095 0.0541 0.1271
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.0632 0.0632
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.011 0.0644 0.0643
Schistosoma mansoni multidrug resistance protein 0.0056 0.0286 0.0286
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0369 0.0368
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0088 0.0087
Schistosoma mansoni jumonji domain containing protein 0.0053 0.0263 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0284 0.0284
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.016 0.016
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0014 0.0003 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0251 0.1581 0.1581
Mycobacterium tuberculosis Probable oxidoreductase 0.048 0.31 0.6863
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0012 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.1013 0.2237
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0078 0.0078
Brugia malayi intermediate filament protein 0.0052 0.0258 0.0604
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0065 0.0201
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0008 0.0007
Loa Loa (eye worm) Smad1 0.0017 0.0027 0.0063
Plasmodium vivax glutathione reductase, putative 0.0189 0.1169 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0632 0.1301
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0161 0.0331
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0191 0.1177 0.1177
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0066 0.0347 0.2138
Loa Loa (eye worm) hypothetical protein 0.0086 0.0481 0.1128
Schistosoma mansoni chromobox protein 0.023 0.1437 0.1437
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0017 0.0027 0.0082
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.001
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.0632 0.1393
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0284 0.0284
Brugia malayi exodeoxyribonuclease III family protein 0.0069 0.0367 0.0862
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0012 0.0017
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0065 0.0123
Schistosoma mansoni rab6-interacting 0.0021 0.0048 0.0047
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0124 0.0124
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0139 0.0649
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.011 0.0331
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0069 0.0367 0.1834
Brugia malayi ABC transporter transmembrane region family protein 0.0056 0.0286 0.0671
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0035 0.0142 0.0772
Schistosoma mansoni synaptojanin 0.0014 0.0003 0.0003
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0017 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0019
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.011 0.0644 0.1998
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0191 0.1177 0.1177
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0056 0.0286 0.1335
Brugia malayi hypothetical protein 0.0021 0.0048 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0124 0.0291
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0124 0.0291
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0027 0.0063
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0284 0.142
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0086 0.0484 0.0484
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0161 0.05
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0646 0.1425
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0152 0.0757
Mycobacterium ulcerans dehydrogenase 0.0017 0.0027 0.0006
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0013 0 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Brugia malayi CCR4 0.0014 0.0003 0.0007
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Schistosoma mansoni rab6-interacting 0.0021 0.0048 0.0047
Brugia malayi MAP kinase sur-1 0.0056 0.0284 0.0667
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0124 0.0291
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0541 0.0541
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0646 0.0646
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0161 0.0331
Entamoeba histolytica hypothetical protein 0.0069 0.0369 0.1146
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0017 0.0027 0.0027
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0284 0.142
Schistosoma mansoni hypothetical protein 0.0069 0.0369 0.0369
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0405 0.0405
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0038 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0124 0.0291
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0124 0.0124
Schistosoma mansoni nocturnin 0.0014 0.0003 0.0003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.0027 0.0055
Giardia lamblia hypothetical protein 0.0014 0.0003 0.0009
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0043 0.0195 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0129 0.0767 0.1572
Onchocerca volvulus 0.0021 0.0048 0.0092
Loa Loa (eye worm) hypothetical protein 0.0056 0.0286 0.0671
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.011 0.0226
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0741 0.074
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0646 0.1998
Plasmodium falciparum thioredoxin reductase 0.0066 0.0347 0.2967
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0014 0.0003 0.0007
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0139 0.0326
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0014 0.0003 0.001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0369 0.2282
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0161 0.1374
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0026 0.0219
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0152 0.0151
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0693 0.4516 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0069 0.0369 0.0369
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0048 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0632 0.1301
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0066 0.0347 0.0814
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0067 0.0354 0.0353
Echinococcus granulosus smad 0.0017 0.0027 0.0027
Trypanosoma brucei hypothetical protein, conserved 0.0013 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0377
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Entamoeba histolytica disulphide oxidoreductase, putative 0.0017 0.0027 0.0084
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0016
Trichomonas vaginalis hypothetical protein 0.0038 0.0161 0.0331
Echinococcus granulosus Smad4 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0014 0.0003 0.0016
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0139 0.1189
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0741 0.1739
Brugia malayi Protein cec-1. 0.0038 0.0161 0.0377
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Brugia malayi RNA binding protein 0.0125 0.0741 0.1739
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0069 0.0367 0.1834
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0335 0.214 0.5027
Loa Loa (eye worm) hypothetical protein 0.0094 0.0535 0.1257
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0065 0.0151
Schistosoma mansoni cpg binding protein 0.0059 0.0304 0.0304
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0017 0.0027 0.0084
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0284 0.0667
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0124 0.0291
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0139 0.0696
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0017 0.0027 0.0124
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Brugia malayi MH1 domain containing protein 0.0017 0.0027 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0256 0.1612 0.3786
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0066 0.0347 0.1733
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.0027 0.0055
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.001
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0741 0.074
Entamoeba histolytica multidrug resistance protein, putative 0.0056 0.0286 0.0888
Entamoeba histolytica MIR domain protein 0.0021 0.0048 0.0149
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0124 0.0124
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0017 0.0027 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.002 0.0036
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0588 0.138
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0242 0.0499
Echinococcus multilocularis lysine specific demethylase 5A 0.0025 0.0075 0.0074
Brugia malayi hypothetical protein 0.0124 0.0734 0.1724
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.0632 0.1393
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0048 0.0047
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0124 0.0124
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0013 0 0.0002
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0008 0.0007
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0077 0.0159
Giardia lamblia Fructose-bisphosphate aldolase 0.0498 0.322 1
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0017 0.0027 0.0062
Giardia lamblia Multidrug resistance-associated protein 1 0.0056 0.0286 0.0887
Loa Loa (eye worm) hypothetical protein 0.0272 0.1721 0.4042
Giardia lamblia ABC transporter, putative 0.0056 0.0286 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Loa Loa (eye worm) hypothetical protein 0.0129 0.0767 0.18
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0012 0.0011
Echinococcus granulosus lamin dm0 0.0052 0.0258 0.0257
Schistosoma mansoni glutamate synthase 0.0017 0.0027 0.0027
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0048 0.0405
Onchocerca volvulus 0.0101 0.0582 0.1192
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0043 0.0195 0.0194
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0284 0.0586
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0101 0.0237
Onchocerca volvulus 0.0021 0.0048 0.0092
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0003 0.0016
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0017 0.0027 0.0084
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0012 0.0026
Brugia malayi Smad1 0.0017 0.0027 0.0063
Entamoeba histolytica thioredoxin reductase, putative 0.0017 0.0027 0.0084
Brugia malayi latrophilin 2 splice variant baaae 0.0186 0.1148 0.2697
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0017 0.0027 0.0055
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.011 0.0511
Toxoplasma gondii exonuclease III APE 0.0069 0.0367 0.1714
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0142 0.0709
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0017 0.0027 0.0124
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0101 0.0582 0.1366
Echinococcus multilocularis microtubule associated protein 2 0.1518 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0124 0.0291
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0002
Echinococcus granulosus intermediate filament protein 0.0052 0.0258 0.0257
Echinococcus granulosus inositol monophosphatase 1 0.0035 0.0142 0.0142
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0027 0.0063
Leishmania major pentamidine resistance protein 1 0.0056 0.0286 0.1429
Chlamydia trachomatis thioredoxin reductase 0.0017 0.0027 0.002
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0017 0.0027 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0065 0.0136
Brugia malayi hypothetical protein 0.0015 0.0012 0.0026
Schistosoma mansoni inositol 145-trisphosphate receptor 0.058 0.3766 0.3766
Loa Loa (eye worm) hypothetical protein 0.0108 0.0632 0.1484
Plasmodium falciparum heterochromatin protein 1 0.0038 0.0161 0.1374
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0017 0.0027 0.0134
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Echinococcus multilocularis chromobox protein 1 0.023 0.1437 0.1437
Loa Loa (eye worm) heterochromatin protein 1 0.023 0.1437 0.3375
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0161 0.0331
Brugia malayi nuclear receptor RXR 0.0017 0.0024 0.0055
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0284 0.142
Trichomonas vaginalis inositol monophosphatase, putative 0.0035 0.0142 0.0292
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0035 0.0143 0.0335
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0014 0.0003 0.0003
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0012 0.0011
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0066 0.0347 0.0347
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Brugia malayi Calcitonin receptor-like protein seb-1 0.0272 0.1721 0.4042
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0152 0.0151
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0017 0.0027 0.0227
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0152 0.0151
Echinococcus granulosus chromobox protein 2 0.0038 0.0161 0.0161
Brugia malayi Valyl-tRNA synthetase 0.0038 0.0161 0.0377
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Plasmodium vivax ferrodoxin reductase, putative 0.0017 0.0027 0.0227
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0161 0.05
Onchocerca volvulus 0.0017 0.0027 0.0049
Toxoplasma gondii hypothetical protein 0.003 0.0107 0.05
Echinococcus granulosus lysine specific demethylase 5A 0.003 0.0108 0.0108
Loa Loa (eye worm) programmed cell death 8 0.0017 0.0027 0.0062
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus multilocularis PHD finger protein rhinoceros 0.002 0.0046 0.0046
Schistosoma mansoni lipoxygenase 0.0086 0.0482 0.0482
Brugia malayi hypothetical protein 0.0038 0.0162 0.0379
Loa Loa (eye worm) hypothetical protein 0.0042 0.0193 0.0453
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0029 0.0029
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.001
Trichomonas vaginalis glutathione reductase, putative 0.0066 0.0347 0.0715
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0066 0.0347 0.0347
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0086 0.0484 0.1136
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0012 0.0011
Echinococcus granulosus bloom syndrome protein 0.0025 0.0077 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0124 0.0291
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0124 0.0124
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0831 0.1712
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0056 0.0286 0.1429
Mycobacterium ulcerans NADH dehydrogenase 0.0017 0.0027 0.0006
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0014 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.0632 0.4035
Brugia malayi Latrophilin receptor protein 2 0.0086 0.0484 0.1136
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.011 0.0644 0.0643
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0014 0.0003 0.0016
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0014 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0051 0.0251 0.0589
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0168
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0014 0.0003 0.0007
Schistosoma mansoni chromobox protein 0.0038 0.0161 0.0161
Echinococcus granulosus ryanodine receptor 44f 0.0094 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0065 0.0259
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0139 0.0696
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0205 0.0421
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0008 0.0008
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0014 0.0003 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.002 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.1518 1 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0013 0 0.0002
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0107 0.0262
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0345 0.0345
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0124 0.0291
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0056 0.0286 0.1429
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0065 0.0151
Schistosoma mansoni lamin 0.0052 0.0258 0.0257
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0014 0.0003 0.0016
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0066 0.0347 0.1733
Schistosoma mansoni inositol monophosphatase 0.0035 0.0142 0.0142
Leishmania major trypanothione reductase 0.0189 0.1169 0.5838
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0258 0.0604
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.002 0.0036
Echinococcus multilocularis Chromobox protein 3 0.0038 0.0161 0.0161
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Brugia malayi ecdysone receptor 0.0015 0.0012 0.0026
Trichomonas vaginalis esterase, putative 0.0108 0.0632 0.1301
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0069 0.0367 0.0806
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0017 0.0027 0.0052
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0524 0.339 0.339
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0124 0.0291
Trichomonas vaginalis apoptosis inducing factor, putative 0.0017 0.0027 0.0055
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0251 0.1581 0.1581
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0646 0.3227
Mycobacterium ulcerans ferredoxin reductase 0.0017 0.0027 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0242 0.0499
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0646 0.2006
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0013 0 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.0632 0.1484
Echinococcus granulosus neuropeptide receptor A26 0.0462 0.2981 0.2981
Schistosoma mansoni ryanodine receptor related 0.0131 0.0784 0.0784
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0369 0.0368
Mycobacterium ulcerans monoxygenase 0.0017 0.0027 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0026 0.005
Mycobacterium ulcerans beta-lactamase 0.0108 0.0632 0.4035
Brugia malayi hypothetical protein 0.0017 0.0024 0.0055
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0066 0.0347 0.1733
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0017 0.0027 0.0227
Trypanosoma cruzi trypanothione reductase, putative 0.0189 0.1169 0.5838
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus multilocularis neuropeptide s receptor 0.0462 0.2981 0.2981
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0014 0.0003 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0251 0.1581 0.1581
Brugia malayi Bromodomain containing protein 0.0023 0.0063 0.0146
Onchocerca volvulus 0.0108 0.0632 0.1295
Brugia malayi beta-lactamase 0.0108 0.0632 0.1484
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0272 0.1721 0.4042
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0168
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0026 0.0219
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0086 0.0484 0.0484
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0015 0.001 0.0048
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0646 0.2006
Entamoeba histolytica hypothetical protein 0.0038 0.0161 0.05
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0123 0.0728 0.0727
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0014 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0632 0.1484
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0012 0.0011
Brugia malayi ecdysteroid receptor 0.0032 0.0124 0.0291
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0017 0.0027 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0151
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0124 0.0124
Echinococcus granulosus jumonji domain containing protein 0.0028 0.0099 0.0099
Brugia malayi glutathione reductase 0.0189 0.1169 0.2745
Brugia malayi hypothetical protein 0.0069 0.0369 0.0866
Trypanosoma cruzi mitochondrial protein 99, putative 0.0014 0.0003 0.0016
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Onchocerca volvulus 0.0038 0.0161 0.0325
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0108 0.0254
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0046 0.0215
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0654 0.4257 1
Brugia malayi Heterochromatin protein 1 0.023 0.1437 0.3375
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.001
Brugia malayi Bromodomain containing protein 0.0081 0.0451 0.1058
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0369 0.0865
Loa Loa (eye worm) thioredoxin reductase 0.0189 0.1169 0.2745
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.011 0.0226
Schistosoma mansoni chromobox protein 0.023 0.1437 0.1437
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0432 0.278 0.6153
Brugia malayi 6-phosphofructokinase 0.0111 0.0646 0.1517
Echinococcus granulosus neutral sphingomyelinase 0.0014 0.0003 0.0003
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0741 0.074
Echinococcus granulosus chromobox protein 1 0.023 0.1437 0.1437
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0065 0.0324
Schistosoma mansoni synaptojanin 0.0014 0.0003 0.0003
Brugia malayi M-phase phosphoprotein, mpp8 0.0038 0.0161 0.0377
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0112 0.0657 0.3067
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0014 0.0003 0.0003
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0012 0.0026
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.0027 0.0134
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0741 0.1739
Loa Loa (eye worm) hypothetical protein 0.0335 0.214 0.5027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0026
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0042 0.0042
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0315 0.2002 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0069 0.0367 0.1834
Onchocerca volvulus 0.0021 0.0048 0.0092
Treponema pallidum NADH oxidase 0.0066 0.0347 0.1069
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0024 0.0023
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0056 0.0286 0.1429
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0048 0.0047
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Onchocerca volvulus 0.0038 0.0161 0.0325
Brugia malayi PHD-finger family protein 0.002 0.0046 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0124 0.0291
Echinococcus granulosus cpg binding protein 0.0059 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0108 0.0632 0.1484
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.011 0.0226
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis glutamate synthase, putative 0.0017 0.0027 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0124 0.0291
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0243 0.1528 0.4883
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0284 0.0284
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0038 0.0161 0.0161
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0014 0.0003 0.0007
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0013 0 0.0002
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0017 0.0027 0.0006
Brugia malayi cation channel family protein 0.0617 0.4014 0.9429
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0124 0.0291
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Mycobacterium ulcerans hypothetical protein 0.0023 0.0065 0.0259
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0017 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0315 0.2002 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.1177 0.7668
Schistosoma mansoni hypothetical protein 0.0086 0.0484 0.0484
Echinococcus multilocularis survival motor neuron protein 1 0.0499 0.3229 0.3229
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0017 0.0027 0.0027
Brugia malayi MH2 domain containing protein 0.0256 0.1612 0.3786
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0124 0.0124
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0377
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0066 0.0347 0.0762
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0069 0.0367 0.2272
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0013 0 0.0001
Brugia malayi Bromodomain containing protein 0.004 0.0176 0.0413
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0284 0.0284
Schistosoma mansoni sulfide quinone reductase 0.0017 0.0027 0.0027
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0124 0.0124
Echinococcus multilocularis geminin 0.0933 0.6115 0.6115
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Leishmania major RNA-editing complex protein MP100, putative 0.0014 0.0003 0.0016
Trichomonas vaginalis mannosyltransferase 1, putative 0.0021 0.0048 0.0099
Brugia malayi Death domain containing protein 0.0015 0.0008 0.0017
Schistosoma mansoni hypothetical protein 0.0933 0.6115 0.6115
Giardia lamblia MRP-like ABC transporter 0.0056 0.0286 0.0887
Brugia malayi jmjC domain containing protein 0.003 0.0108 0.0254
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0242 0.0499
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0124 0.0124
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0284 0.142
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0046 0.0108
Toxoplasma gondii thioredoxin reductase 0.0189 0.1169 0.546
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0347 0.1733
Loa Loa (eye worm) hypothetical protein 0.0323 0.2056 0.4829
Loa Loa (eye worm) ryanodine receptor 0.0035 0.0147 0.0344
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0014 0.0003 0.0016
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0017 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Echinococcus granulosus dnaJ subfamily B 0.04 0.2571 0.257
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0077 0.0077
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0139 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0331
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0013 0 0.0002
Schistosoma mansoni cpg binding protein 0.0054 0.0271 0.027
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0014 0.0003 0.0013
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.011 0.0644 0.1511
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0013 0 0.0001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0124 0.0249
Brugia malayi TAR-binding protein 0.0125 0.0741 0.1739
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Trichomonas vaginalis chromobox protein, putative 0.023 0.1437 0.2959
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0012 0.0026
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0284 0.142
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.0027 0.0055
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0124 0.0291
Brugia malayi hypothetical protein 0.0017 0.0024 0.0055
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0077 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0632 0.3156
Loa Loa (eye worm) hypothetical protein 0.0542 0.3514 0.8254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0498 0.322 0.663
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0013 0 0.0001
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0048 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0251 0.1581 0.1581
Onchocerca volvulus 0.0015 0.0012 0.0017
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0124 0.0124
Onchocerca volvulus 0.0015 0.0012 0.0017
Onchocerca volvulus Alhambra homolog 0.002 0.0046 0.0089
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0013 0 0.0002
Schistosoma mansoni hypothetical protein 0.002 0.0046 0.0046
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0056 0.0286 0.1429

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 1070 nM Calcium mobilization in saponin permeabilised SH-SY5Y neuroblastoma cells at a pH of 7.2 ChEMBL. 8145238
EC50 (functional) = 1491 nM Calcium mobilization in saponin permeabilised SH-SY5Y neuroblastoma cells at a pH of 7.6 ChEMBL. 8145238
EC50 (functional) = 3676 nM Calcium mobilization in saponin permeabilised SH-SY5Y neuroblastoma cells at a pH of 6.8 ChEMBL. 8145238
IC50 (binding) = 5652 nM Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 7.6 using [3H]Ins(1,4,5)P3 as the radioligand. ChEMBL. 8145238
IC50 (binding) = 9114 nM Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 6.8 using [3H]Ins(1,4,5)P3 as the radioligand. ChEMBL. 8145238

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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