Detailed information for compound 300954

Basic information

Technical information
  • TDR Targets ID: 300954
  • Name: (E)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin- 3-ylprop-2-en-1-amine
  • MW: 317.224 | Formula: C16H17BrN2
  • H donors: 0 H acceptors: 1 LogP: 3.91 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C/C=C(/c1cccnc1)\c1ccc(cc1)Br)C
  • InChi: 1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9+
  • InChiKey: OYPPVKRFBIWMSX-CXUHLZMHSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridyl)prop-2-en-1-amine
  • (E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridyl)-2-propen-1-amine
  • (E)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-3-yl-prop-2-en-1-amine
  • [(E)-3-(4-bromophenyl)-3-(3-pyridyl)allyl]-dimethyl-amine
  • Zimeldine
  • [(E)-3-(4-bromophenyl)-3-(3-pyridyl)prop-2-enyl]-dimethyl-amine
  • Prestwick3_000092
  • BSPBio_000044
  • Lopac-Z-101
  • NCGC00014683-02
  • BPBio1_000050
  • NCGC00014683
  • NSC-305352
  • NCGC00025286-01
  • Tocris-1767

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Rattus norvegicus Serotonin transporter Starlite/ChEMBL References
Homo sapiens hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens arachidonate 15-lipoxygenase Starlite/ChEMBL No references
Homo sapiens arachidonate 15-lipoxygenase, type B Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Rattus norvegicus Muscarinic acetylcholine receptor M1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131074 All targets in OG5_131074
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi hypothetical protein Get druggable targets OG5_131074 All targets in OG5_131074
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypoxia-induced factor 1 Get druggable targets OG5_131074 All targets in OG5_131074
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi hypoxia-induced factor 1 Get druggable targets OG5_131074 All targets in OG5_131074
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni amine GPCR Muscarinic acetylcholine receptor M1   460 aa 463 aa 27.0 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Serotonin transporter   630 aa 629 aa 47.1 %
Echinococcus multilocularis sodium and chloride dependent glycine Serotonin transporter   630 aa 617 aa 39.4 %
Plasmodium vivax hypothetical protein, conserved Serotonin transporter   630 aa 528 aa 21.2 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Serotonin transporter   630 aa 585 aa 34.2 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Serotonin transporter   630 aa 581 aa 40.1 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 582 aa 35.2 %
Schistosoma mansoni sodium/chloride dependent transporter Serotonin transporter   630 aa 605 aa 37.7 %
Schistosoma mansoni sodium/chloride dependent transporter Serotonin transporter   630 aa 552 aa 41.5 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Serotonin transporter   630 aa 638 aa 25.1 %
Onchocerca volvulus Serotonin transporter   630 aa 611 aa 26.4 %
Echinococcus multilocularis serotonin receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Echinococcus granulosus arachidonate 5 lipoxygenase arachidonate 15-lipoxygenase 662 aa 590 aa 23.9 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Muscarinic acetylcholine receptor M1   460 aa 462 aa 23.4 %
Brugia malayi Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 576 aa 30.9 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Serotonin transporter   630 aa 520 aa 36.2 %
Brugia malayi cytochrome P450 cytochrome P450, family 2, subfamily D, polypeptide 6 497 aa 425 aa 32.0 %
Onchocerca volvulus Transmembrane protein 120 homolog Serotonin transporter   630 aa 571 aa 31.2 %
Echinococcus granulosus biogenic amine 5HT receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Plasmodium knowlesi transporter, putative Serotonin transporter   630 aa 514 aa 20.2 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 509 aa 28.3 %
Echinococcus granulosus sodium and chloride dependent glycine Serotonin transporter   630 aa 617 aa 39.4 %
Loa Loa (eye worm) hypothetical protein Muscarinic acetylcholine receptor M1   460 aa 425 aa 22.1 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 576 aa 31.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major histone deacetylase, putative 0.0216 0.0444 0.1628
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0033
Plasmodium vivax histone deacetylase 2, putative 0.0075 0.0135 0.0496
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0016 0.0026
Plasmodium vivax glutathione reductase, putative 0.0057 0.0095 0.035
Echinococcus granulosus histone deacetylase 0.0075 0.0135 0.029
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0013 0.0037
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0016 0.0026
Trichomonas vaginalis ran, putative 0.0021 0.0017 0.0278
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0015 0.0033
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0056
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0188 0.0381 0.315
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0131 0.0179
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0017 0.0037
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0016 0.0006 0.002
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0062 0.0134
Onchocerca volvulus 0.0028 0.0031 0.0031
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0013 0.022
Loa Loa (eye worm) histone deacetylase 0.0075 0.0135 0.0856
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0017 0.0036
Echinococcus multilocularis nibrin 0.0021 0.0015 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0039 0.0247
Brugia malayi Doublecortin family protein 0.0048 0.0074 0.0102
Schistosoma mansoni coup transcription factor 0.0021 0.0015 0.0033
Echinococcus granulosus Niemann Pick C1 protein 0.0435 0.0922 0.1988
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0016 0.0044
Echinococcus multilocularis chromobox protein 1 0.0084 0.0154 0.0283
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0031 0.0042
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0015 0.0247
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0015 0.0033
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0016 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0131 0.0931
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0051 0.0109
Toxoplasma gondii histone deacetylase HDAC4 0.0075 0.0135 0.0496
Echinococcus multilocularis serotonin receptor 0.0028 0.0031 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Leishmania major mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0024
Echinococcus multilocularis chromobox protein 1 0.0084 0.0154 0.0283
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Schistosoma mansoni DNA ligase IV 0.0021 0.0015 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0096
Brugia malayi cytochrome P450 0.0021 0.0016 0.0022
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0011 0.0038
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0008 0.0015
Brugia malayi intermediate filament protein 0.003 0.0037 0.005
Trypanosoma brucei mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0013 0.0006
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0015 0.0033
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0013 0.0079
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0131 0.0256 0.1629
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0043 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0016 0.0044
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0005 0.0006
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0004 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0037 0.0135
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0062 0.0114
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0016 0.0026
Onchocerca volvulus Protein patched homolog 0.0018 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0232
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0013 0.0207
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0051
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0017 0.004
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0216 0.0444 0.7426
Schistosoma mansoni biogenic amine receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0209 0.0428 0.0784
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Echinococcus granulosus chromobox protein 2 0.0014 0 0.0001
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0061
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0054 0.034
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0017 0.0036
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0017 0.005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0108
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0016 0.0026
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0154 0.0981
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0031 0.0195
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0004 0.0009
Schistosoma mansoni loxhd1 0.0048 0.0074 0.016
Schistosoma mansoni histone deacetylase 4 5 0.0075 0.0135 0.029
Echinococcus granulosus dna polymerase eta 0.0019 0.0013 0.0027
Echinococcus multilocularis histone deacetylase 3 0.0216 0.0444 0.0814
Brugia malayi histone deacetylase 3 (HD3) 0.0216 0.0444 0.0611
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0016 0.0006 0.0012
Brugia malayi hypothetical protein 0.0021 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0096
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0016 0.0046
Echinococcus multilocularis cpg binding protein 0.0033 0.0042 0.0077
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0 0.0001
Onchocerca volvulus 0.003 0.0037 0.0036
Onchocerca volvulus 0.0149 0.0297 0.0296
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0031 0.0056
Brugia malayi Patched protein homolog 1 0.0018 0.0011 0.0014
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0031 0.0066
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0026
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0074 0.0136
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.008 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0131 0.2048
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0015 0.0028
Echinococcus granulosus neuropeptide receptor 0.0028 0.0031 0.0066
Schistosoma mansoni lipoxygenase 0.0209 0.0428 0.0922
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Brugia malayi G-protein coupled receptor 0.0028 0.0031 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0016 0.0006 0.002
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0209 0.0428 0.0922
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0028
Brugia malayi Pre-SET motif family protein 0.0252 0.0522 0.0719
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Toxoplasma gondii histone deacetylase HDAC3 0.0216 0.0444 0.1638
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0165 0.0355
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Echinococcus granulosus histone deacetylase 6 0.0075 0.0135 0.029
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0002 0.0005
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.0648 0.4128
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0017 0.0087
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Echinococcus granulosus importin subunit beta 1 0.0029 0.0034 0.0072
Toxoplasma gondii hypothetical protein 0.0031 0.0038 0.0139
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1251 0.271 1
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Schistosoma mansoni hypothetical protein 0.0034 0.0045 0.0097
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0034 0.0103
Schistosoma mansoni histone deacetylase 0.0216 0.0444 0.0957
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0008 0.005
Echinococcus granulosus histone deacetylase 8 0.0075 0.0135 0.029
Onchocerca volvulus 0.0016 0.0006 0.0005
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0004 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0015 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0016 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0021
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Echinococcus granulosus Chromo domain 0.0014 0 0.0001
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0008 0.0015
Brugia malayi histone deacetylase 1 (HD1) 0.0216 0.0444 0.0611
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0031 0.0042
Brugia malayi hypothetical protein 0.0147 0.0292 0.0402
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.009 0.0331
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0028
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0015 0.0033
Schistosoma mansoni chromobox protein 0.0084 0.0154 0.0333
Echinococcus granulosus serotonin receptor 0.0028 0.0031 0.0066
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0013 0.0029
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0031 0.0066
Echinococcus granulosus nibrin 0.0021 0.0015 0.0032
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0131 0.0469
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0131 0.0931
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0034
Echinococcus granulosus muscleblind protein 0.0462 0.0981 0.2114
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0015 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0017 0.0104
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0038 0.0082
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0381 0.0821
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0031 0.0066
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0031 0.0066
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0044 0.0066 0.0244
Echinococcus multilocularis histone deacetylase 1 0.0216 0.0444 0.0814
Onchocerca volvulus 0.0028 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0009 0.0138
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0031 0.0066
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Schistosoma mansoni chromobox protein 0.0014 0 0.0001
Schistosoma mansoni hypothetical protein 0.0014 0 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0031 0.0066
Onchocerca volvulus 0.005 0.0081 0.008
Brugia malayi DNA polymerase I family protein 0.0018 0.001 0.0014
Schistosoma mansoni histone deacetylase 1 2 3 0.0075 0.0135 0.029
Schistosoma mansoni topbp1 0.0021 0.0015 0.0032
Leishmania major histone deacetylase, putative 0.0075 0.0135 0.0485
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0039 0.0131
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0013 0.0194
Leishmania major importin beta-1 subunit, putative 0.0024 0.0022 0.0067
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Loa Loa (eye worm) oxidoreductase 0.0022 0.0017 0.0108
Mycobacterium leprae putative cytochrome p450 0.0021 0.0016 0.0436
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Treponema pallidum DNA ligase (lig) 0.0021 0.0015 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0021
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0048 0.0802
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0016 0.0006 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0131 0.2048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0096
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni hypothetical protein 0.0441 0.0936 0.2017
Onchocerca volvulus 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0022 0.0358
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0031 0.0066
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0048 0.0802
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0017 0.0267
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0038 0.0082
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0015 0.0028
Brugia malayi TAR-binding protein 0.0193 0.0393 0.0541
Echinococcus multilocularis Niemann Pick C1 protein 0.0435 0.0922 0.169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0031 0.0056
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0216 0.0444 0.7426
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0016 0.0044
Mycobacterium ulcerans hypothetical protein 0.0073 0.0131 0.0931
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0004 0.0055
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0017 0.006
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.024
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0023
Onchocerca volvulus 0.0031 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0031 0.0056
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0031 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0031 0.0066
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0017 0.0108
Leishmania major histone deacetylase, putative 0.0216 0.0444 0.1628
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0013 0.022
Echinococcus granulosus RUN 0.0048 0.0074 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0015 0.0247
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0287 0.2351
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0117 0.0742
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0074 0.016
Leishmania major hypothetical protein, conserved 0.0016 0.0006 0.0008
Schistosoma mansoni ran 0.0021 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0462 0.0981 0.6246
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0038 0.0082
Onchocerca volvulus 0.0028 0.0031 0.0031
Echinococcus granulosus survival motor neuron protein 1 0.0731 0.1571 0.3384
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.037 0.2353
Plasmodium falciparum histone deacetylase, putative 0.0075 0.0135 0.0496
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Entamoeba histolytica hypothetical protein 0.0024 0.0022 0.0336
Brugia malayi neuropeptide F receptor 0.0028 0.0031 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0309 0.0647 0.1394
Trypanosoma brucei trypanothione reductase 0.0057 0.0095 0.0331
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0038 0.024
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0139
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0117 0.0252
Echinococcus granulosus lamin dm0 0.003 0.0037 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0055
Brugia malayi Uncoordinated protein 44 0.0017 0.0008 0.0011
Brugia malayi prolyl 4-hydroxylase 0.0016 0.0006 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0038 0.0082
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0013 0.0037
Giardia lamblia Telomerase catalytic subunit 0.1251 0.271 1
Loa Loa (eye worm) histone deacetylase 1 0.0216 0.0444 0.2827
Echinococcus multilocularis sex peptide receptor 0.0028 0.0031 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0033
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0062 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0028
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0016 0.0026
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0154 0.2578
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0002 0.0002
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0 0.0001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0015 0.0033
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0017 0.0036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Toxoplasma gondii helicase, putative 0.0018 0.001 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0182 0.037 0.2353
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0017 0.0063
Onchocerca volvulus 0.0018 0.0011 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0096
Brugia malayi hypothetical protein 0.0197 0.0402 0.0553
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0017 0.0056
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0004 0.0008
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0031 0.0056
Schistosoma mansoni histone deacetylase hda2 0.0075 0.0135 0.029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0045 0.0286
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0017 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0031 0.0056
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0062 0.0392
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Echinococcus multilocularis dna polymerase eta 0.0019 0.0013 0.0023
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0051 0.0186
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.008 0.011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.0324
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Chlamydia trachomatis protoporphyrinogen oxidase 0.0042 0.0062 0.5601
Onchocerca volvulus 0.0037 0.0051 0.0051
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0031 0.0195
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0051 0.0093
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0188 0.0381 0.1395
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Plasmodium falciparum 5'-3' exonuclease, N-terminal resolvase-like domain, putative 0.0045 0.0068 0.0251
Schistosoma mansoni ran 0.0021 0.0017 0.0036
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0033
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0131 0.0931
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0108
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0224
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0016 0.0026
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Onchocerca volvulus 0.0014 0 0.0000000055107
Brugia malayi histone deacetylase 11 0.0075 0.0135 0.0185
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0017 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii histone deacetylase HDAC1 0.0075 0.0135 0.0496
Toxoplasma gondii histone deacetylase HDAC5 0.0075 0.0135 0.0498
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0038 0.0139
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0043 0.0719
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0381 0.291
Mycobacterium ulcerans dehydrogenase 0.0042 0.0062 0.0392
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0074 0.0136
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0287 1
Trichomonas vaginalis set domain proteins, putative 0.0287 0.0598 1
Onchocerca volvulus 0.0022 0.0017 0.0017
Mycobacterium tuberculosis Probable DNA polymerase I PolA 0.0063 0.0108 0.0831
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus histone deacetylase 1 0.0216 0.0444 0.0957
Onchocerca volvulus 0.0021 0.0015 0.0015
Loa Loa (eye worm) RNA binding protein 0.0193 0.0393 0.25
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Onchocerca volvulus 0.0287 0.0598 0.0598
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0015 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0051 0.0109
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0017 0.0056
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Brugia malayi Dopamine receptor 0.0028 0.0031 0.0042
Plasmodium falciparum thioredoxin reductase 0.0057 0.0095 0.035
Brugia malayi SWIRM domain containing protein 0.0042 0.0062 0.0085
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0015 0.0032
Toxoplasma gondii thioredoxin reductase 0.0057 0.0095 0.035
Brugia malayi CHD4 protein 0.0016 0.0004 0.0005
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0062 0.0229
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0216 0.0444 0.7426
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0081 0.0081
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0015 0.0033
Schistosoma mansoni single-minded 0.0059 0.0099 0.0213
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0075 0.0135 0.0856
Loa Loa (eye worm) hypothetical protein 0.0033 0.0043 0.027
Schistosoma mansoni survival motor neuron protein 0.0149 0.0297 0.0639
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni hypothetical protein 0.0175 0.0354 0.0763
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0038 0.007
Schistosoma mansoni hypothetical protein 0.031 0.0648 0.1397
Brugia malayi hypothetical protein 0.0731 0.1571 0.2163
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0381 0.291
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0017 0.0108
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0017 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Brugia malayi hypothetical protein 0.0111 0.0214 0.0294
Schistosoma mansoni ap endonuclease 0.0021 0.0017 0.0036
Echinococcus multilocularis histone deacetylase 7 0.0075 0.0135 0.0247
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0051 0.0109
Onchocerca volvulus 0.0018 0.0011 0.001
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0131 0.0931
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0016 0.0006 0.0008
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0287 0.2351
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0031 0.0056
Treponema pallidum DNA polymerase I (polA) 0.0063 0.0108 0.2665
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0023
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0135 0.0247
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0021
Brugia malayi Telomerase reverse transcriptase 0.3329 0.726 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Probable 5'-3' exonuclease 0.0045 0.0068 0.049
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0031 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0007 0.0119
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0017 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus dnaJ subfamily B 0.0441 0.0936 0.2017
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0016 0.0058
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0051
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0015 0.0055
Echinococcus multilocularis histone deacetylase 8 0.0075 0.0135 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0256 0.428
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0004 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis musashi 0.003 0.0037 0.0067
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0017 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0062 0.0229
Onchocerca volvulus 0.0018 0.0011 0.001
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0016 0.0026
Schistosoma mansoni importin beta-1 0.0029 0.0034 0.0072
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0131 0.0179
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0017 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Echinococcus granulosus chromobox protein 1 0.0084 0.0154 0.0333
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0015 0.0021
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0013 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0021
Brugia malayi Dopamine receptor protein 2 0.0028 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Mycobacterium leprae PROBABLE DNA POLYMERASE I POLA 0.0063 0.0108 0.3697
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0131 0.0179
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0017 0.0063
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0038 0.007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0017 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Echinococcus multilocularis snurportin 1 0.031 0.0648 0.1188
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0034 0.0062
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0016 0.0006 0.0012
Brugia malayi Patched related family protein 12 0.0018 0.0011 0.0014
Mycobacterium tuberculosis Probable reductase 0.013 0.0255 0.208
Brugia malayi Dopamine receptor protein 1 0.0028 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0004 0.0025
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0037 0.0115
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0015 0.0033
Echinococcus granulosus serotonin transporter 0.0182 0.037 0.0797
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Mycobacterium ulcerans 5'-3' exonuclease 0.0045 0.0068 0.044
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0131 0.4479
Trypanosoma cruzi mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0024
Echinococcus multilocularis histone deacetylase 0.0075 0.0135 0.0247
Echinococcus granulosus g protein coupled receptor 0.0028 0.0031 0.0066
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0046 0.0099
Leishmania major telomerase reverse transcriptase, putative 0.1251 0.271 1
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Schistosoma mansoni opsin-like receptor 0.0028 0.0031 0.0066
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0015 0.0032
Leishmania major GTP-binding protein, putative 0.0021 0.0017 0.0049
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0466
Echinococcus multilocularis Ankyrin 0.0018 0.0008 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni histamine h1 receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0042 0.0062 0.2071
Loa Loa (eye worm) histone deacetylase 3 0.0216 0.0444 0.2827
Echinococcus multilocularis dnaJ subfamily B 0.0441 0.0936 0.1714
Echinococcus granulosus orexin receptor type 2 0.0028 0.0031 0.0066
Schistosoma mansoni cpg binding protein 0.0033 0.0042 0.009
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0031 0.0042
Echinococcus granulosus g protein coupled receptor 0.0028 0.0031 0.0066
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0031 0.0066
Leishmania major DNA polymerase eta, putative 0.0019 0.0013 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0037 0.0135
Echinococcus granulosus dna polymerase kappa 0.0019 0.0013 0.0027
Echinococcus granulosus histone deacetylase 3 0.0216 0.0444 0.0957
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0052
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0038 0.007
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0016 0.0044
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni cpg binding protein 0.0031 0.0038 0.0082
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0065 0.0416
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0031 0.0056
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0013 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0061 0.0132
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.0393 0.25
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0073 0.0073
Schistosoma mansoni biogenic amine receptor 0.0028 0.0031 0.0066
Schistosoma mansoni rab6-interacting 0.0048 0.0074 0.016
Onchocerca volvulus 0.0031 0.0038 0.0038
Schistosoma mansoni intermediate filament proteins 0.003 0.0037 0.0079
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0031 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0016 0.0044
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0131 0.0469
Schistosoma mansoni chromobox protein 0.0084 0.0154 0.0333
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0017 0.0036
Leishmania major UDP-galactopyranose mutase 0.0042 0.0062 0.0217
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0055
Onchocerca volvulus 0.0028 0.0031 0.0031
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0015 0.0021
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0038 0.007
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0031 0.0042
Brugia malayi Serotonin receptor 0.0028 0.0031 0.0042
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0031 0.0066
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0015 0.0247
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0031 0.0066
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0031 0.0066
Brugia malayi Histone deacetylase family protein 0.0075 0.0135 0.0185
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0004 0.0055
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0008 0.0018
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0031 0.0042
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0598 0.1279 1
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0015 0.0096
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0008 0.0018
Brugia malayi Patched related family protein 4 0.0018 0.0011 0.0014
Brugia malayi Myosin head containing protein 0.0018 0.0011 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0081 0.0174
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0188 0.0381 0.0821
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0054 0.0098
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0017 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0017 0.0284
Schistosoma mansoni microtubule-associated protein tau 0.2133 0.4641 1
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0017 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0039 0.0131
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0031 0.0056
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0031 0.0031
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0051
Echinococcus granulosus neuropeptide receptor 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0131 0.102
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0017 0.0031
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0016 0.0026
Echinococcus granulosus Protein patched homolog 1 0.0131 0.0256 0.0552
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0017 0.0023
Leishmania major cytochrome p450-like protein 0.0021 0.0016 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0031 0.0195
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0056
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0031 0.0066
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0017 0.0256
Schistosoma mansoni hypothetical protein 0.0111 0.0214 0.046
Leishmania major hypothetical protein, conserved 0.003 0.0037 0.0123
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0006 0.0035
Echinococcus granulosus lamin 0.003 0.0037 0.0079
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0255 0.8878
Loa Loa (eye worm) serotonin transporter b 0.0182 0.037 0.2353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Onchocerca volvulus 0.0048 0.0074 0.0074
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Echinococcus multilocularis expressed conserved protein 0.0286 0.0596 0.1092
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0037 0.0135
Brugia malayi follicle stimulating hormone receptor 0.0028 0.0031 0.0042
Onchocerca volvulus 0.0028 0.0031 0.0031
Trypanosoma brucei histone deacetylase 4 0.0075 0.0135 0.0477
Onchocerca volvulus 0.0028 0.0031 0.0031
Onchocerca volvulus 0.0031 0.0038 0.0038
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0004 0.0055
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0287 0.2351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0017 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Schistosoma mansoni hypothetical protein 0.0149 0.0297 0.0639
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0008 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0031 0.0195
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0045 0.0062
Brugia malayi hypothetical protein 0.003 0.0037 0.005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0052
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0033
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0099 0.0213
Brugia malayi Histone deacetylase family protein 0.0075 0.0135 0.0185
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0255 0.208
Schistosoma mansoni netrin receptor unc5 0.0017 0.0008 0.0018
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0214 0.046
Entamoeba histolytica Ran family GTPase 0.0021 0.0017 0.0261
Brugia malayi sulfakinin receptor protein 0.0028 0.0031 0.0042
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0017 0.006
Echinococcus granulosus cpg binding protein 0.0033 0.0042 0.009
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0016 0.0006 0.002
Schistosoma mansoni ap endonuclease 0.0021 0.0017 0.0036
Onchocerca volvulus 0.0022 0.0017 0.0017
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0008 0.0008
Schistosoma mansoni amine oxidase 0.0042 0.0062 0.0134
Leishmania major mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0239
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0017 0.0063
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Toxoplasma gondii 5'-3' exonuclease, N-terminal resolvase family domain-containing protein 0.0022 0.0018 0.0066
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0065 0.012
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0013 0.0034
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.0393 0.0541
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0038 0.0082
Schistosoma mansoni hypothetical protein 0.0175 0.0354 0.0763
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0131 0.0931
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis Niemann Pick C1 protein 0.0304 0.0636 0.1166
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.037 0.0797
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0013 0.0027
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0255 0.208
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0017 0.0048
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0017 0.0041
Brugia malayi Death domain containing protein 0.0017 0.0008 0.0011
Brugia malayi RE15519p 0.0028 0.0031 0.0042
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0031 0.0195
Brugia malayi steroid hormone receptor 0.0021 0.0015 0.0021
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0034 0.0123
Echinococcus multilocularis lamin 0.003 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0013 0.0037
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0062 0.0229
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0038 0.0082
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0033
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0016 0.0026
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.001
Chlamydia trachomatis DNA polymerase I 0.0063 0.0108 1
Plasmodium falciparum glutathione reductase 0.0057 0.0095 0.035
Plasmodium vivax multidomain scavenger receptor, putative 0.0048 0.0074 0.0274
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0017 0.0022
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0016 0.0044
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0004 0.0055
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0016 0.0046
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Plasmodium vivax patched family protein, putative 0.0018 0.0011 0.0038
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Brugia malayi neuropeptide F receptor 0.0028 0.0031 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0304 0.0636 1
Entamoeba histolytica hypothetical protein 0.0021 0.0015 0.0232
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0031 0.0056
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0015 0.0033
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0031 0.0195
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0002 0.0002
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0073 0.0131 0.083
Brugia malayi hypothetical protein 0.0042 0.0062 0.0085
Loa Loa (eye worm) hypothetical protein 0.0216 0.0444 0.2827
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0016 0.0006 0.0034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.009 0.0611
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0368 0.2343
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Leishmania major cytochrome p450-like protein 0.0031 0.0039 0.0131
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0013 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.037 0.0797
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0304 0.0636 0.4051
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0232
Brugia malayi G-protein coupled receptor 0.0028 0.0031 0.0042
Trypanosoma cruzi histone deacetylase 1, putative 0.0216 0.0444 0.1628
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis lamin dm0 0.003 0.0037 0.0067
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Giardia lamblia Histone deacetylase 0.0216 0.0444 0.16
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0004 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0062 0.0229
Echinococcus granulosus death domain containing protein 0.0017 0.0008 0.0018
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0028 0.0031 0.0195
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0015 0.0033
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0031 0.0056
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0149 0.0297 0.0408
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) cytochrome P450 0.0021 0.0016 0.01
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.009 0.0675
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0026
Loa Loa (eye worm) glutathione reductase 0.0057 0.0095 0.0604
Leishmania major hypothetical protein, unknown function 0.0016 0.0006 0.0008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0214 0.046
Onchocerca volvulus 0.0028 0.0031 0.0031
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0017 0.0043
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0038 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0017 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0015 0.0021
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Trypanosoma brucei unspecified product 0.0019 0.0013 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0031 0.0066
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus granulosus g protein coupled receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0039 0.0247
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Echinococcus multilocularis GPCR, family 2 0.0016 0.0005 0.0009
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0015 0.002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0015 0.0015
Brugia malayi hypothetical protein 0.002 0.0013 0.0018
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Brugia malayi Cytochrome P450 family protein 0.0031 0.0039 0.0053
Onchocerca volvulus 0.0042 0.0062 0.0062
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0015 0.017
Loa Loa (eye worm) hypothetical protein 0.0131 0.0256 0.1629
Plasmodium falciparum thioredoxin reductase 0.002 0.0013 0.0049
Trypanosoma brucei histone deacetylase 3 0.0075 0.0135 0.0477
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Brugia malayi Protein kinase domain containing protein 0.0017 0.0008 0.0011
Brugia malayi Pre-SET motif family protein 0.0037 0.0051 0.0069
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0015 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0015 0.0055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0031 0.0056
Trichomonas vaginalis DNA polymerase I, putative 0.0018 0.001 0.0165
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0017 0.0036
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0135 0.0247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0096
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Onchocerca volvulus 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Plasmodium vivax telomerase reverse transcriptase, putative 0.1251 0.271 1
Echinococcus granulosus histone deacetylase 7 0.0075 0.0135 0.029
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0013 0.0037
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.0522 0.3322
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0043
Toxoplasma gondii hypothetical protein 0.0031 0.0038 0.0139
Brugia malayi PAS domain containing protein 0.0059 0.0099 0.0136
Schistosoma mansoni lamin 0.003 0.0037 0.0079
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0013 0.0049
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0381 0.0821
Echinococcus multilocularis neuropeptide receptor A26 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0731 0.1571 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0009
Echinococcus multilocularis geminin 0.0175 0.0354 0.0649
Mycobacterium ulcerans oxidoreductase 0.0042 0.0062 0.0392
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0016 0.0026
Plasmodium vivax importin-beta 2, putative 0.0029 0.0034 0.0123
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0031 0.0031
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0017 0.0036
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0017 0.0056
Onchocerca volvulus 0.0022 0.0017 0.0017
Echinococcus granulosus intermediate filament protein 0.003 0.0037 0.0079
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1251 0.271 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0131 0.083
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Brugia malayi putative neuropeptide receptor 0.0028 0.0031 0.0042
Brugia malayi hypothetical protein 0.0048 0.0074 0.0102
Echinococcus granulosus Chromobox protein 3 0.0014 0 0.0001
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0013 0.0049
Echinococcus multilocularis tar DNA binding protein 0.0193 0.0393 0.072
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0016 0.0044
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0004 0.0055
Toxoplasma gondii histone deacetylase HDAC2 0.0216 0.0444 0.1638
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0255 0.208
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0034 0.0103
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0031 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0031 0.0056
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0031 0.0066
Trypanosoma cruzi histone deacetylase 1, putative 0.0216 0.0444 0.1628
Echinococcus multilocularis RUN 0.0048 0.0074 0.0136
Schistosoma mansoni myosin xvIII 0.0028 0.0031 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Brugia malayi topoisomerase 0.0021 0.0015 0.002
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0031 0.0066
Echinococcus granulosus histone deacetylase 6 0.0075 0.0135 0.029
Loa Loa (eye worm) TAR-binding protein 0.0193 0.0393 0.25
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0015 0.0033
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Onchocerca volvulus 0.0018 0.0011 0.001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0031 0.0056
Brugia malayi larval opioid receptor 0.0028 0.0031 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0031 0.0056
Schistosoma mansoni patched 1 0.0131 0.0256 0.0552
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0 0.0001
Toxoplasma gondii exonuclease III APE 0.0021 0.0017 0.006
Echinococcus multilocularis survival motor neuron protein 1 0.0731 0.1571 0.2877
Onchocerca volvulus 0.0028 0.0031 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0131 0.102
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Plasmodium vivax SET domain protein, putative 0.0037 0.0051 0.0186
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0016 0.0046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0016 0.0044
Plasmodium vivax histone deacetylase, putative 0.0075 0.0135 0.0496
Loa Loa (eye worm) hypothetical protein 0.016 0.032 0.2039
Schistosoma mansoni DNA polymerase I 0.0018 0.001 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0016 0.0257
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0017 0.0037
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0383 0.0809 0.515
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0054 0.0074
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0017 0.0031
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0015 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0017 0.0325
Leishmania major cytochrome p450-like protein 0.0021 0.0016 0.0046
Schistosoma mansoni histone deacetylase 4 5 0.0075 0.0135 0.029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0021
Onchocerca volvulus 0.0182 0.037 0.0369
Brugia malayi nuclear hormone receptor 0.0021 0.0015 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0081 0.1355
Brugia malayi Histone deacetylase 1 0.0216 0.0444 0.0611
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0016 0.0044
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0016
Plasmodium falciparum plastid replication-repair enzyme 0.0018 0.001 0.0036
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0031 0.0195
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0026
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Onchocerca volvulus 0.0043 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0037 0.0232
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0061 0.0132
Entamoeba histolytica DNA-directed DNA polymerase, putative 0.0018 0.001 0.0155
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0106
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0015 0.0247
Loa Loa (eye worm) histone deacetylase 7A 0.0075 0.0135 0.0856
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0013 0.0018
Loa Loa (eye worm) hypothetical protein 0.0182 0.037 0.2353
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0016 0.0006 0.001
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Brugia malayi Thioredoxin reductase 0.0057 0.0095 0.0131
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Brugia malayi Niemann-Pick C1 protein precursor 0.0304 0.0636 0.0876
Loa Loa (eye worm) hypothetical protein 0.0182 0.037 0.2353
Plasmodium falciparum histone deacetylase 2 0.0075 0.0135 0.0496
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0556 0.1187 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0005 0.0029
Onchocerca volvulus 0.0018 0.0011 0.001
Plasmodium falciparum transporter, putative 0.0031 0.0038 0.0139
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi protein C24B5.3 0.0018 0.0011 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Echinococcus multilocularis microtubule associated protein 2 0.2133 0.4641 0.8502
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0031 0.0066
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Plasmodium falciparum glutathione reductase 0.002 0.0013 0.0049
Echinococcus granulosus Ankyrin 0.0018 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni histone deacetylase hda2 0.0075 0.0135 0.029
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0013 0.0944
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0016 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Brugia malayi Patched related family protein 10 0.0018 0.0011 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0139
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0013 0.0049
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0031 0.0056
Schistosoma mansoni polycystin 1-related 0.0048 0.0074 0.016
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0031 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0021
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0022 0.0358
Loa Loa (eye worm) hypothetical protein 0.0197 0.0402 0.2556
Brugia malayi ecdysteroid receptor 0.0021 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi RNA binding protein 0.0193 0.0393 0.0541
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0017 0.0036
Loa Loa (eye worm) doublecortin family protein 0.0048 0.0074 0.0472
Schistosoma mansoni hypothetical protein 0.0048 0.0074 0.016
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0031 0.0066
Plasmodium vivax histone deacetylase 1, putative 0.0216 0.0444 0.1638
Trypanosoma brucei histone deacetylase 2 0.0075 0.0135 0.0477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0062 0.0229
Treponema pallidum sodium- and chloride- dependent transporter 0.0182 0.037 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0031 0.0056
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0017 0.0482
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0016 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0015 0.0033
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0037 0.005
Brugia malayi Cytochrome P450 family protein 0.0031 0.0039 0.0053
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0038 0.0052
Brugia malayi Serotonin receptor 0.0028 0.0031 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0031 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Echinococcus granulosus hypothetical protein 0.0028 0.0031 0.0066
Onchocerca volvulus 0.0031 0.0038 0.0038
Leishmania major histone deacetylase, putative 0.0075 0.0135 0.0485
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.009 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0013 0.0029
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0016 0.0026
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0016 0.0436
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0255 0.208
Schistosoma mansoni amine oxidase 0.0042 0.0062 0.0134
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0062 0.0085
Mycobacterium ulcerans DNA polymerase I 0.0063 0.0108 0.0756
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0255 0.208
Plasmodium vivax amine transporter, putative 0.0031 0.0038 0.0139
Onchocerca volvulus 0.0018 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0029
Chlamydia trachomatis DNA ligase 0.0021 0.0015 0.1098
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0013 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0024
Echinococcus multilocularis muscleblind protein 0.0462 0.0981 0.1797
Schistosoma mansoni biogenic amine receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0015 0.0096
Onchocerca volvulus Protein patched homolog 0.0018 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Trypanosoma brucei histone deacetylase 1 0.0216 0.0444 0.1622
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0009 0.0138
Toxoplasma gondii hypothetical protein 0.0018 0.0011 0.0038
Echinococcus granulosus microtubule associated protein 2 0.2133 0.4641 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0031 0.0066
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0062 0.0229
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0031 0.0056
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0031 0.0056
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0031 0.0066
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0016 0.0026
Echinococcus multilocularis 0.0042 0.0062 0.0114
Onchocerca volvulus 0.0022 0.0017 0.0017
Onchocerca volvulus 0.0021 0.0015 0.0015
Brugia malayi SET domain containing protein 0.0016 0.0005 0.0006
Trypanosoma brucei mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0017
Brugia malayi ORL1-like opioid receptor 0.0028 0.0031 0.0042
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0074 0.016
Trypanosoma brucei mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0017
Echinococcus multilocularis serotonin receptor 0.0028 0.0031 0.0056
Plasmodium vivax plastid replication-repair enzyme, putative 0.0018 0.001 0.0036
Brugia malayi Cytochrome P450 family protein 0.0021 0.0016 0.0022
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0031 0.0066
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0015 0.0043
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0016 0.0026
Brugia malayi GnHR receptor homolog 0.0028 0.0031 0.0042
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0017 0.0036
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.008 0.0508
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0039 0.0247
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0095 0.0205
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.005 0.008 0.0508
Echinococcus granulosus neuropeptide receptor A26 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0021
Echinococcus granulosus Niemann Pick C1 protein 0.0304 0.0636 0.1371
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Toxoplasma gondii aldehyde dehydrogenase 0.0188 0.0381 0.1406
Echinococcus multilocularis somatostatin receptor 0.0028 0.0031 0.0056
Echinococcus granulosus fmrfamide receptor 0.0028 0.0031 0.0066
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0039 0.0209
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0482
Echinococcus multilocularis serotonin transporter 0.0182 0.037 0.0677
Loa Loa (eye worm) histone deacetylase 11 0.0075 0.0135 0.0856
Brugia malayi Melatonin receptor type 1A 0.0028 0.0031 0.0042
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0015 0.0033
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Onchocerca volvulus 0.003 0.0037 0.0036
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0016 0.0044
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0062 0.0134
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0016 0.0257
Brugia malayi Importin beta-1 subunit 0.0029 0.0034 0.0046
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0015 0.0028
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0031 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0021
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0008 0.0018
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0135 0.0247
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0018
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0031 0.0066
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0004 0.0008
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0095 0.0718
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0031 0.0195
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0037 0.0123
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0016 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Echinococcus multilocularis sterol regulatory element binding protein 0.0131 0.0256 0.0469
Trypanosoma cruzi mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0016 0.0044
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0016 0.0044
Schistosoma mansoni adenoreceptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Plasmodium falciparum importin beta, putative 0.0029 0.0034 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2506 0.5458 1
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0131 0.2048
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi CXXC zinc finger family protein 0.0031 0.0038 0.0052
Brugia malayi Heterochromatin protein 1 0.0084 0.0154 0.0212
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0017 0.0036
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0015 0.0406
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0037 0.0123
Trypanosoma cruzi mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0239
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0017 0.0063
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0013 0.0034
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0031 0.0066
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0598 0.1279 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0015 0.0009
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0017 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus geminin 0.0175 0.0354 0.0763
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0381 0.291
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0033
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0095 0.0604
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0017
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0139
Echinococcus granulosus histone deacetylase 6 0.0075 0.0135 0.029
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0017 0.0061
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0188 0.0381 0.0698
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0017 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Brugia malayi Muscleblind-like protein 0.0462 0.0981 0.1351
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Brugia malayi DKFZp564C0469 protein 0.0021 0.0015 0.002
Echinococcus granulosus chromobox protein 1 0.0084 0.0154 0.0333
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0015 0.0055
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0065 0.009
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0016 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0016 0.0044
Onchocerca volvulus 0.0028 0.0031 0.0031
Leishmania major protein kinase, putative 0.002 0.0015 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0095 0.0339
Brugia malayi protein C24B5.3 0.0018 0.0011 0.0014
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0037 0.0135
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0013 0.0017
Onchocerca volvulus 0.0073 0.0131 0.013
Echinococcus granulosus neuropeptide s receptor 0.0028 0.0031 0.0066
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0031 0.0056
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0154 0.2578
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0214 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0073 0.1223
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0031 0.0066
Brugia malayi nuclear receptor NHR-88 0.0021 0.0015 0.0021
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0031 0.0056
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0031 0.0042
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0031 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0021
Echinococcus granulosus single minded 2 0.0047 0.0073 0.0157
Plasmodium falciparum LCCL domain-containing protein 0.0048 0.0074 0.0274
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus multilocularis protein dispatched 1 0.0149 0.0296 0.0543
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0017 0.0056
Trypanosoma brucei telomerase reverse transcriptase 0.1251 0.271 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0131 0.0469
Echinococcus granulosus sex peptide receptor 0.0028 0.0031 0.0066
Echinococcus granulosus allatostatin A receptor 0.0028 0.0031 0.0066
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0081 0.1355
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.037 0.2353
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0017 0.0284
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0062 0.0392
Schistosoma mansoni histone deacetylase 0.0216 0.0444 0.0957
Echinococcus granulosus sterol regulatory element binding protein 0.0131 0.0256 0.0552
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Plasmodium falciparum telomerase reverse transcriptase 0.1251 0.271 1
Echinococcus granulosus somatostatin receptor 0.0028 0.0031 0.0066
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0048 0.0074 0.0472
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0054 0.0116
Echinococcus multilocularis protein patched 0.0131 0.0256 0.0469
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.001
Echinococcus multilocularis neuropeptide s receptor 0.0028 0.0031 0.0056
Brugia malayi chromobox protein homolog 3 0.0047 0.0073 0.0101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0051 0.0109
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0131 0.0931
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni topbp1 0.0021 0.0015 0.0032
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0016 0.0044
Plasmodium falciparum histone deacetylase 1 0.0216 0.0444 0.1638
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0131 0.4479
Wolbachia endosymbiont of Brugia malayi DNA polymerase I 0.0063 0.0108 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0062 0.0134
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0031 0.0066
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0015 0.0247
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0013 0.0037
Schistosoma mansoni lamin 0.003 0.0037 0.0079
Brugia malayi hypothetical protein 0.0048 0.0074 0.0102
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0028
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0038 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0017 0.0272
Schistosoma mansoni chromobox protein 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0004 0.0009
Onchocerca volvulus 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0073 0.0131 0.083
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.009 0.8247
Mycobacterium tuberculosis Possible oxidoreductase 0.0042 0.0062 0.0439
Leishmania major DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.032
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0034
Schistosoma mansoni opsin-like receptor 0.0028 0.0031 0.0066
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0062 0.0134
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0016 0.0026
Brugia malayi AKH receptor 0.0028 0.0031 0.0042
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0028
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0004 0.0021
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0013 0.0207
Onchocerca volvulus 0.0048 0.0074 0.0074
Echinococcus granulosus GPCR family 2 0.0016 0.0005 0.001
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0031 0.0066
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0101 0.0374
Schistosoma mansoni lipoxygenase 0.0123 0.024 0.0518
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0033
Toxoplasma gondii DNA polymerase I domain-containing protein 0.0018 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0017 0.0056
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni rab6-interacting 0.0048 0.0074 0.016
Echinococcus granulosus expressed conserved protein 0.0286 0.0596 0.1284
Echinococcus granulosus tar DNA binding protein 0.0193 0.0393 0.0847
Echinococcus multilocularis muscleblind protein 1 0.0462 0.0981 0.1797
Schistosoma mansoni DNA polymerase eta 0.0019 0.0013 0.0027
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0016 0.0026
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0031 0.0066
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0015 0.0232
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0038 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0016 0.0044
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0004 0.0055
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0095 0.0174
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0066
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0002 0.0004
Onchocerca volvulus 0.0028 0.0031 0.0031
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0062 0.0217
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0062 0.0217
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.037 0.0509
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0015 0.0043
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi glutathione reductase 0.0057 0.0095 0.0131
Loa Loa (eye worm) intermediate filament protein 0.003 0.0037 0.0232
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0005
Onchocerca volvulus 0.0018 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Onchocerca volvulus Histone deacetylase 10 homolog 0.0075 0.0135 0.0134
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0031 0.0038 0.3281
Echinococcus granulosus Polycystic kidney disease protein 0.0048 0.0074 0.016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0031 0.0056
Brugia malayi RNA, U transporter 1 0.0083 0.0151 0.0207
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0017 0.0048
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0165 0.0302
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0013 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0048 0.0074 0.0472
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0031 0.0066
Brugia malayi G protein-coupled receptor 0.0028 0.0031 0.0042
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0062 0.0229
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Entamoeba histolytica histone deacetylase, putative 0.0216 0.0444 0.6977
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0031 0.0056
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0062 0.0439
Brugia malayi CHE-14 protein 0.0131 0.0256 0.0352
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Echinococcus multilocularis Polycystic kidney disease protein 0.0048 0.0074 0.0136
Loa Loa (eye worm) hypothetical protein 0.0462 0.0981 0.6246
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trypanosoma brucei histone deacetylase, putative 0.0075 0.0135 0.0477
Toxoplasma gondii RNA-directed DNA polymerase 0.1251 0.271 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0021
Leishmania major trypanothione reductase 0.0057 0.0095 0.0339
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0031 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0031 0.0066
Brugia malayi hypothetical protein 0.0031 0.0038 0.0052
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0073 0.1223
Plasmodium vivax 5'-3' exonuclease, N-terminal resolvase-like domain, putative 0.0045 0.0068 0.0251
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0031 0.0066
Brugia malayi hypothetical protein 0.0021 0.0015 0.002
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0039 0.0124
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0062 0.0229
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0016 0.0026
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0031 0.0056
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0004 0.0006
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0031 0.0066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0008 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0022 0.0358
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus granulosus snurportin 1 0.031 0.0648 0.1397
Schistosoma mansoni cpg binding protein 0.0033 0.0042 0.009
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0031 0.0056
Plasmodium vivax histone deacetylase, putative 0.0075 0.0135 0.0496
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0022 0.0067
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0131 0.0931
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0013 0.0017
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0005 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Brugia malayi Cytochrome P450 family protein 0.0067 0.0117 0.0161
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0051 0.0093
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0017 0.0272
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0095 0.035
Onchocerca volvulus 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0285 0.0594 0.3782
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0038 0.007
Schistosoma mansoni cytochrome P450 0.0021 0.0016 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Brugia malayi hypoxia-induced factor 1 0.0182 0.0368 0.0507
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0031 0.0195
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0016 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis 0.0021 0.0016 0.0029
Schistosoma mansoni opsin-like receptor 0.0028 0.0031 0.0066
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0017 0.0056

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.511886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.511886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 3.16227766 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 5.011872336 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 15.84893192 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 25.11886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 39.81071706 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
ED50 (functional) = 25 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
ED50 (functional) = 25 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
ED50 (functional) = 49 uM kg-1 In vivo inhibition of accumulation of [14C]-5-HT (5-HT) in mouse brain slices after intraperitoneal administration ChEMBL. 6458703
ED50 (functional) > 98 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
ED50 (functional) > 98 uM kg-1 In vivo inhibition of accumulation of (-)-[3H]-Norepinephrine (NA) in mouse brain slices after intraperitoneal administration ChEMBL. 6458703
ED50 (functional) > 98 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
IC50 (binding) Inhibition of cruzain (unknown origin) in presence of 0.01% Triton X-100 ChEMBL. 18333608
IC50 (binding) Inhibition of cruzain (unknown origin) ChEMBL. 18333608
IC50 (binding) 0 Inhibition of ChEMBL. 18333608
IC50 (binding) 0 Inhibition of chymotrypsin (unknown origin) in presence of 0.1% Triton X-100 ChEMBL. 18333608
IC50 (binding) 0 Inhibition of malate dehydrogenase (unknown origin) ChEMBL. 18333608
IC50 (binding) 0 Inhibition of malate dehydrogenase (unknown origin) in presence of 0.1% Triton X-100 ChEMBL. 18333608
IC50 (binding) 0 Inhibition of cruzain (unknown origin) ChEMBL. 18333608
IC50 (binding) 0 Inhibition of cruzain (unknown origin) in presence of 0.01% Triton X-100 ChEMBL. 18333608
IC50 (functional) = 0.15 uM In vitro inhibition of the accumulation of (-)-[3H]-Norepinephrine in synaptosomes from the rat brain cortex ChEMBL. 2966246
IC50 (functional) = 0.22 uM In vitro inhibition of the accumulation of (-)-[3H]-5-HT in synaptosomes from the rat brain cortex ChEMBL. 2966246
IC50 (functional) = 1.7 uM In vitro inhibition of accumulation of [14C]-5-HT (5-HT) in mouse brain slices ChEMBL. 6458703
IC50 (functional) = 6.1 uM In vitro inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 6.1 uM In vitro inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 6.1 uM In vitro inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 6.1 uM In vitro inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 24 uM In vitro inhibition of accumulation of (-)-[3H]-Norepinephrine (NA) in mouse brain slices ChEMBL. 6458703
IC50 (binding) > 600 uM Inhibition of beta-lactamase AmpC (unknown origin) ChEMBL. 18333608
IC50 (binding) > 600 uM Inhibition of chymotrypsin (unknown origin) ChEMBL. 18333608
Potency (functional) = 1.2589 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Agonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 915 ] ChEMBL. No reference
Potency (functional) = 1.2589 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.2589 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 914 ] ChEMBL. No reference
Potency (ADMET) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Agonists for NFkB Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 895 ] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Antagonists for NFkB Signaling Pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ] ChEMBL. No reference
Potency (ADMET) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Measurement of IP-One Response. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Ratio (functional) = 0.68 Selectivity expressed as ratio between NE and 5-HT uptake inhibition in rat synaptosomes ChEMBL. 2966246
Ratio (functional) = 1 Selectivity expressed as ratio between NE and 5-HT uptake inhibition in mouse brain slices ChEMBL. 2966246

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 2966246

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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