Detailed information for compound 59397

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 197.661 | Formula: C10H12ClNO
  • H donors: 2 H acceptors: 1 LogP: 1.97 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC1CCc2c(C1)cc(c(c2)O)Cl
  • InChi: 1S/C10H12ClNO/c11-9-4-7-3-8(12)2-1-6(7)5-10(9)13/h4-5,8,13H,1-3,12H2
  • InChiKey: OYXMLNKSERZKSD-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Echinococcus multilocularis tyrosine protein kinase shark 0.0728 0.1701 0.2335
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0468 0.0952 0.1196
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0143 0.0017 0.0021
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0163 0.0074 0.0093
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.071 0.1651 0.2266
Trichomonas vaginalis AGC family protein kinase 0.0524 0.1114 0.1799
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0333 0.0564 0.0943
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1132 0.2868 0.3605
Trypanosoma cruzi NIMA-related kinase, putative 0.0154 0.0048 0.0088
Plasmodium vivax unspecified product 0.0611 0.1366 0.4083
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0321 0.0528 0.0528
Echinococcus granulosus Vam6:Vps39 protein 0.032 0.0527 0.0527
Schistosoma mansoni protein kinase 0.0611 0.1366 0.3288
Echinococcus multilocularis cyclin dependent kinase 7 0.0197 0.017 0.0233
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0434 0.0855 0.1444
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0382 0.0706 0.0887
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Echinococcus granulosus tensin 0.0152 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.071 0.1651 0.3981
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0524 0.1114 0.1114
Entamoeba histolytica protein kinase, putative 0.0221 0.024 0.0366
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0221 0.024 0.0366
Chlamydia trachomatis DNA gyrase subunit B 0.0301 0.047 0.4036
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.0618 0.1465
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Schistosoma mansoni serine/threonine-protein kinase 0.1392 0.3618 0.8773
Echinococcus multilocularis serine threonine protein kinase 0.1201 0.3067 0.421
Onchocerca volvulus 0.1602 0.4223 0.8457
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0185 0.0136 0.0195
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0143 0.0017 0.0023
Echinococcus multilocularis signal transduction protein lnk realted 0.0152 0.004 0.0056
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0214 0.0219 0.0219
Echinococcus multilocularis serine:threonine protein kinase N2 0.0405 0.077 0.1057
Entamoeba histolytica hypothetical protein 0.0221 0.024 0.0366
Echinococcus granulosus activin receptor type 0.0664 0.1517 0.1517
Plasmodium vivax tyrosine kinase-like protein, putative 0.0216 0.0225 0.0631
Echinococcus granulosus casein kinase I alpha 0.0352 0.0619 0.0619
Echinococcus multilocularis neuroglian 0.0175 0.0106 0.0146
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0382 0.0706 0.3307
Schistosoma mansoni kinase 0.0168 0.0087 0.0172
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Loa Loa (eye worm) hypothetical protein 0.0163 0.0074 0.0093
Echinococcus multilocularis N chimaerin 0.0315 0.0512 0.0702
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0866 0.2101 0.6305
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0954 0.2354 0.2959
Brugia malayi Variant SH3 domain containing protein 0.0264 0.0365 0.0459
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0143 0.0017 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0642 0.1456 0.1829
Brugia malayi STAT protein, DNA binding domain containing protein 0.0152 0.004 0.0051
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0393 0.0736 1
Brugia malayi probable protein kinase 0.0748 0.1761 0.2213
Giardia lamblia Kinase, NEK 0.0434 0.0854 0.2533
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0221 0.024 0.062
Trichomonas vaginalis CMGC family protein kinase 0.0333 0.0564 0.0897
Echinococcus multilocularis titin 0.0233 0.0276 0.0379
Entamoeba histolytica SH2 domain containing protein 0.0152 0.004 0.0039
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0183 0.013 0.013
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0334 0.0566 0.0711
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0333 0.0564 0.2626
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0321 0.0528 0.0837
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0233 0.0276 0.0347
Echinococcus multilocularis cyclin dependent kinase 9 0.0177 0.0112 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.0711 0.1691
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0152 0.004 0.0056
Loa Loa (eye worm) TK/EPH protein kinase 0.0393 0.0736 0.0925
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.071 0.1651 0.1651
Toxoplasma gondii CMGC kinase, CK2 family 0.0611 0.1366 0.2324
Echinococcus multilocularis twitchin 0.0195 0.0166 0.0227
Schistosoma mansoni serine/threonine kinase 0.0563 0.1226 0.2947
Plasmodium vivax DNA gyrase subunit B, putative 0.0393 0.0736 0.2175
Schistosoma mansoni growth factor receptor-bound protein 0.0264 0.0365 0.0849
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Schistosoma mansoni SH2A 0.0152 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.032 0.0527 0.0663
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0781 0.1856 0.1856
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0245 0.031 0.039
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0143 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Echinococcus multilocularis serine:threonine protein kinase 0.0367 0.066 0.0906
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0136 0.029
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0221 0.024 0.1072
Echinococcus multilocularis aurora kinase A 0.0524 0.1114 0.153
Loa Loa (eye worm) hypothetical protein 0.0163 0.0074 0.0093
Entamoeba histolytica hypothetical protein 0.0145 0.002 0.0006
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.022 0.0238 0.0238
Echinococcus multilocularis dual specificity 0.0497 0.1036 0.1422
Onchocerca volvulus 0.0706 0.164 0.3264
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0221 0.024 0.062
Echinococcus granulosus protein kinase 0.0428 0.0837 0.0837
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0315 0.0512 0.0512
Loa Loa (eye worm) hypothetical protein 0.0264 0.0365 0.0459
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1132 0.2868 0.3937
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0186 0.0138 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0564 0.1333
Loa Loa (eye worm) hypothetical protein 0.0364 0.0651 0.0819
Schistosoma mansoni protein kinase 0.0281 0.0414 0.0967
Trichomonas vaginalis CMGC family protein kinase 0.0516 0.1091 0.176
Echinococcus granulosus fibroblast growth factor receptor 4 0.0756 0.1783 0.1783
Echinococcus multilocularis tyrosine protein kinase Fgr 0.071 0.1651 0.2266
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus granulosus cyclin dependent kinase 1 0.0563 0.1225 0.1225
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.032 0.0527 0.1244
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0722 0.1686 0.2119
Entamoeba histolytica PH domain containing protein kinase, putative 0.1392 0.3618 0.5901
Brugia malayi Protein kinase domain containing protein 0.0234 0.0277 0.0348
Echinococcus multilocularis calcium dependent protein kinase 0.0202 0.0186 0.0255
Echinococcus multilocularis casein kinase I alpha 0.0352 0.0619 0.085
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0048 0.0052
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0321 0.0528 0.088
Loa Loa (eye worm) hypothetical protein 0.0766 0.1813 0.2278
Trichomonas vaginalis AGC family protein kinase 0.0221 0.024 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0563 0.1225 0.198
Echinococcus multilocularis transfer RNA-Thr 0.0325 0.0541 0.0743
Loa Loa (eye worm) AGC/PKA protein kinase 0.0866 0.2101 0.2641
Entamoeba histolytica protein kinase, putative 0.0317 0.0517 0.0819
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0706 0.1129
Plasmodium falciparum NIMA related kinase 2 0.0154 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0316 0.0514 0.0645
Echinococcus granulosus roundabout 2 0.0175 0.0106 0.0106
Brugia malayi Protein kinase domain containing protein 0.1462 0.3818 0.4799
Brugia malayi Protein kinase domain containing protein 0.0384 0.0711 0.0893
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0152 0.004 0.0051
Leishmania major protein kinase, putative 0.0221 0.024 0.1072
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.0538 0.1271
Brugia malayi C-terminal src kinase protein 1 0.0143 0.0017 0.0021
Leishmania major casein kinase II, putative 0.0611 0.1366 0.6475
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0559 0.1215 0.1527
Trichomonas vaginalis STE family protein kinase 0.0281 0.0414 0.0651
Loa Loa (eye worm) hypothetical protein 0.063 0.1419 0.1784
Loa Loa (eye worm) TK/RYK protein kinase 0.0143 0.0017 0.0021
Schistosoma mansoni vav2 0.0417 0.0807 0.1925
Loa Loa (eye worm) hypothetical protein 0.0367 0.066 0.083
Giardia lamblia Kinase, CMGC SRPK 0.022 0.0238 0.0668
Leishmania major protein kinase, putative 0.0524 0.1114 0.5266
Echinococcus granulosus expressed protein 0.022 0.0238 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0636 0.1437 0.346
Echinococcus multilocularis mitogen activated protein kinase 3 0.0382 0.0706 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.0424 0.0668
Loa Loa (eye worm) AGC/PKG protein kinase 0.0324 0.0538 0.0677
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.0017 0.0023
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Schistosoma mansoni tyrosine kinase 0.028 0.041 0.0958
Schistosoma mansoni tyrosine kinase 0.0728 0.1701 0.4104
Loa Loa (eye worm) TK/ROR protein kinase 0.022 0.0238 0.0299
Giardia lamblia Kinase, PLK 0.0844 0.2036 0.6109
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0642 0.1456 0.3995
Onchocerca volvulus 0.1648 0.4356 0.8724
Echinococcus granulosus myotubularin protein 13 0.0266 0.0369 0.0369
Trichomonas vaginalis TKL family protein kinase 0.0146 0.0025 0.0014
Entamoeba histolytica diacylglycerol kinase, putative 0.0163 0.0074 0.0094
Echinococcus multilocularis tensin 0.0152 0.004 0.0056
Echinococcus multilocularis rho associated protein kinase 0.1011 0.252 0.3459
Plasmodium falciparum NIMA related kinase 1 0.0434 0.0854 0.2533
Loa Loa (eye worm) hypothetical protein 0.0588 0.1299 0.1633
Echinococcus granulosus activated cdc42 kinase 1 0.0325 0.0541 0.0541
Plasmodium falciparum protein kinase 5 0.0563 0.1225 0.3656
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0048 0.0052
Echinococcus granulosus serine:threonine protein kinase N2 0.0405 0.077 0.077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0348 0.0608 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.1307 0.3372 0.8175
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Echinococcus granulosus dual specificity protein kinase clk2 0.0434 0.0855 0.0855
Chlamydia trachomatis DNA gyrase subunit B 0.0393 0.0736 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0143 0.0017 0.0023
Onchocerca volvulus 0.0234 0.0277 0.0524
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.091 0.2227 0.3056
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0216 0.0225 0.0359
Echinococcus granulosus calcium dependent protein kinase 0.0202 0.0186 0.0186
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0642 0.1456 0.6903
Echinococcus granulosus tyrosine protein kinase csk 0.0143 0.0017 0.0017
Echinococcus multilocularis unc 13 (munc13) 0.0173 0.0101 0.0138
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0321 0.0528 0.088
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0866 0.2101 0.5788
Onchocerca volvulus 0.0441 0.0873 0.1723
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Brugia malayi Tyrosine-protein kinase abl-1 0.0655 0.1493 0.1876
Trypanosoma brucei protein kinase, putative 0.0516 0.1091 0.176
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Loa Loa (eye worm) TK protein kinase 0.0833 0.2004 0.2519
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0143 0.0017 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0333 0.0564 0.0897
Echinococcus granulosus casein kinase I alpha 0.0352 0.0619 0.0619
Entamoeba histolytica hypothetical protein 0.0145 0.002 0.0006
Schistosoma mansoni tyrosine kinase 0.1074 0.2699 0.6535
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0143 0.0017 0.0021
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0295 0.0454 0.0717
Toxoplasma gondii AGC kinase 0.2157 0.5824 1
Echinococcus multilocularis casein kinase i 0.0352 0.0619 0.085
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0393 0.0736 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Echinococcus granulosus tyrosine kinase 0.0295 0.0454 0.0454
Onchocerca volvulus 0.0196 0.0167 0.0303
Brugia malayi Protein kinase c protein 2 0.0497 0.1037 0.1303
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0221 0.024 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.0023 0.0011
Echinococcus granulosus serine:threonine protein kinase mig 15 0.063 0.1419 0.1419
Onchocerca volvulus 0.0295 0.0454 0.088
Schistosoma mansoni hypothetical protein 0.0269 0.038 0.0885
Trichomonas vaginalis CK1 family protein kinase 0.0352 0.0619 0.0987
Brugia malayi protein kinase C3,putative 0.0535 0.1146 0.1441
Loa Loa (eye worm) RasGEF domain-containing protein 0.0163 0.0074 0.0093
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0909 0.2224 0.3616
Giardia lamblia Kinase, NEK 0.0434 0.0854 0.2533
Brugia malayi Protein kinase domain containing protein 0.0781 0.1856 0.2333
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0462 0.0936 0.1285
Echinococcus multilocularis tyrosine protein kinase Fyn 0.071 0.1651 0.2266
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2897 0.7956 1
Entamoeba histolytica p21-activated kinase 0.0383 0.0708 0.1132
Trichomonas vaginalis CMGC family protein kinase 0.0234 0.0277 0.0426
Onchocerca volvulus 0.0152 0.004 0.0048
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0631 0.1423 0.1954
Brugia malayi Protein kinase domain 0.0281 0.0412 0.0518
Toxoplasma gondii protein kinase domain-containing protein 0.0221 0.024 0.0385
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus granulosus cyclin dependent kinase 7 0.0197 0.017 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0986 0.2446 0.5918
Plasmodium falciparum casein kinase 1 0.0352 0.0619 0.1822
Schistosoma mansoni serine/threonine protein kinase 0.0497 0.1036 0.2483
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0149 0.0033 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0404 0.0768 0.1231
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0154 0.0048 0.0052
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0737 0.1729 0.1729
Echinococcus granulosus SHC transforming protein 3 0.0152 0.004 0.004
Entamoeba histolytica casein kinase 1, putative 0.0352 0.0619 0.0987
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2036 0.331
Echinococcus multilocularis RNA directed DNA polymerase 0.0206 0.0197 0.0271
Loa Loa (eye worm) hypothetical protein 0.0281 0.0413 0.0519
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0154 0.0048 0.0052
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.046 0.0931 0.0931
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0221 0.024 0.062
Entamoeba histolytica protein kinase, putative 0.0524 0.1114 0.1799
Onchocerca volvulus Serine\/threonine kinase homolog 0.0384 0.0711 0.1395
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0276 0.04 0.0629
Trichomonas vaginalis CK1 family protein kinase 0.0352 0.0619 0.0987
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0245 0.031 0.039
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0221 0.024 0.0676
Onchocerca volvulus 0.0604 0.1344 0.267
Schistosoma mansoni protein kinase 0.0222 0.0244 0.0553
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0462 0.0936 0.1176
Loa Loa (eye worm) hypothetical protein 0.0163 0.0074 0.0093
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2036 0.331
Giardia lamblia Kinase, CMGC CLK 0.0434 0.0855 0.2537
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0359 0.0834
Brugia malayi Protein kinase domain containing protein 0.0295 0.0454 0.0571
Echinococcus granulosus c-Jun N-terminal kinases 0.1079 0.2715 0.2715
Trichomonas vaginalis CMGC family protein kinase 0.0516 0.1091 0.176
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0324 0.0538 0.0898
Loa Loa (eye worm) hypothetical protein 0.0378 0.0694 0.0872
Echinococcus multilocularis Glutaredoxin protein 5 0.1171 0.2981 0.4091
Echinococcus granulosus defective proboscis extension response 0.031 0.0498 0.0498
Echinococcus multilocularis SH2 motif 0.0152 0.004 0.0056
Toxoplasma gondii AGC kinase 0.0866 0.2101 0.3589
Schistosoma mansoni atypical protein kinase C 0.1421 0.3701 0.8976
Trichomonas vaginalis TK family protein kinase 0.0146 0.0023 0.0011
Loa Loa (eye worm) TK protein kinase 0.0143 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.031 0.0498 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0279 0.0638
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus granulosus mitogen activated protein kinase 3 0.0382 0.0706 0.0706
Brugia malayi protein-tyrosine kinase 0.0597 0.1326 0.1666
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0756 0.1783 0.2447
Echinococcus multilocularis serine:threonine protein kinase 3 0.0803 0.1918 0.2632
Loa Loa (eye worm) thyroid receptor interactor 0.0345 0.0598 0.0752
Schistosoma mansoni hypothetical protein 0.0172 0.01 0.0202
Brugia malayi Variant SH3 domain containing protein 0.0264 0.0365 0.0459
Echinococcus granulosus dual specificity mitogen activated protein 0.0281 0.0414 0.0414
Brugia malayi Hr1 repeat family protein 0.1391 0.3613 0.4541
Loa Loa (eye worm) AUR protein kinase 0.0524 0.1114 0.1401
Echinococcus multilocularis tyrosine protein kinase Blk 0.0597 0.1326 0.182
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0563 0.1225 0.2081
Trichomonas vaginalis CMGC family protein kinase 0.0333 0.0564 0.0897
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0781 0.1856 0.2333
Echinococcus multilocularis mitogen activated protein kinase 14 0.0642 0.1456 0.1998
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0986 0.2446 0.2446
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Plasmodium falciparum calcium-dependent protein kinase 3 0.0321 0.0528 0.1546
Entamoeba histolytica protein kinase, putative 0.226 0.6119 1
Brugia malayi Doublecortin family protein 0.0357 0.0633 0.0796
Schistosoma mansoni serine/threonine protein kinase 0.0382 0.0706 0.1679
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0642 0.1456 0.3995
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0563 0.1225 0.5798
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1323 0.3419 0.3419
Loa Loa (eye worm) hypothetical protein 0.0588 0.1299 0.1633
Trichomonas vaginalis AGC family protein kinase 0.0994 0.2471 0.4022
Entamoeba histolytica hypothetical protein 0.0163 0.0074 0.0094
Echinococcus multilocularis geminin 0.0172 0.01 0.0137
Echinococcus granulosus mitogen activated protein kinase 0.0382 0.0706 0.0706
Loa Loa (eye worm) casein kinase 0.0365 0.0656 0.0825
Echinococcus multilocularis tyrosine protein kinase Fyn 0.071 0.1651 0.2266
Loa Loa (eye worm) hypothetical protein 0.0295 0.0454 0.0571
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1117 0.2824 0.2824
Schistosoma mansoni serine/threonine protein kinase 0.0815 0.1954 0.472
Entamoeba histolytica protein kinase, putative 0.226 0.6119 1
Brugia malayi Protein kinase domain containing protein 0.1027 0.2565 0.3224
Loa Loa (eye worm) hypothetical protein 0.0312 0.0501 0.063
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0276 0.04 0.1065
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0709 0.1648 0.2263
Echinococcus multilocularis mitogen activated protein kinase 11 0.0642 0.1456 0.1998
Loa Loa (eye worm) hypothetical protein 0.0175 0.0106 0.0134
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0722 0.1717
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0324 0.0538 0.0739
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0281 0.0412 0.0566
Leishmania major protein kinase, putative 0.0434 0.0855 0.4023
Entamoeba histolytica protein kinase, putative 0.0321 0.0528 0.0837
Echinococcus multilocularis dual specificity 0.0333 0.0564 0.0774
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0866 0.2101 0.3416
Toxoplasma gondii AGC kinase 0.0866 0.2101 0.3589
Echinococcus granulosus tyrosine protein kinase Fps85D 0.091 0.2227 0.2227
Echinococcus multilocularis mitogen activated protein kinase 11 0.0642 0.1456 0.1998
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0706 0.1129
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0173 0.0101 0.0101
Brugia malayi Immunoglobulin I-set domain containing protein 0.0175 0.0106 0.0134
Schistosoma mansoni tyrosine kinase 0.0756 0.1783 0.4303
Echinococcus granulosus dual specificity 0.0333 0.0564 0.0564
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Onchocerca volvulus 0.0352 0.0619 0.1211
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0143 0.0017 0.0017
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0175 0.0106 0.0146
Entamoeba histolytica protein kinase, putative 0.0497 0.1036 0.167
Loa Loa (eye worm) protein kinase domain-containing protein 0.0143 0.0017 0.0021
Plasmodium vivax serine/threonine protein kinase, putative 0.022 0.0238 0.0668
Echinococcus granulosus tyrosine protein kinase shark 0.0728 0.1701 0.1701
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0224 0.0249 0.0645
Trypanosoma brucei protein kinase, putative 0.0221 0.024 0.0366
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0321 0.0528 0.0724
Echinococcus multilocularis receptor type guanylyl cyclase 0.0143 0.0017 0.0023
Schistosoma mansoni tyrosine kinase 0.0408 0.0779 0.1857
Loa Loa (eye worm) TK protein kinase 0.0629 0.1417 0.1781
Echinococcus granulosus serine:threonine protein kinase N2 0.0267 0.0373 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0528 0.0837
Echinococcus granulosus contactin 0.0175 0.0106 0.0106
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0866 0.2101 0.3416
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.2157 0.5824 0.7319
Echinococcus granulosus tyrosine protein kinase Src64B 0.071 0.1651 0.1651
Trichomonas vaginalis STE family protein kinase 0.0276 0.04 0.0629
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.029 0.0438 0.1274
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0285 0.0424 0.0424
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0267 0.0372 0.0372
Entamoeba histolytica protein kinase, putative 0.0214 0.0221 0.0335
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1132 0.2868 0.2868
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0185 0.0136 0.0171
Brugia malayi serine/threonine-protein kinase plk-2 0.0844 0.2036 0.2559
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.1114 0.2674
Schistosoma mansoni protein kinase 0.1132 0.2868 0.6946
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0262 0.0358 0.0949
Brugia malayi SRC-1 0.071 0.1651 0.2075
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1335 0.3453 0.434
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0866 0.2101 0.5788
Echinococcus multilocularis SHC transforming protein 3 0.0152 0.004 0.0056
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0642 0.1456 0.2358
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0293 0.0448 0.0563
Leishmania major casein kinase, putative 0.0352 0.0619 0.289
Echinococcus multilocularis activin receptor type 0.0664 0.1517 0.2083
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0352 0.0619 0.0778
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1267 0.3257 0.4094
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus granulosus hypothetical protein 0.0316 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.1267 0.3257 0.4094
Trichomonas vaginalis STE family protein kinase 0.0281 0.0412 0.0648
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.037 0.067 0.067
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0276 0.04 0.0629
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0143 0.0017 0.0023
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0321 0.0528 0.0663
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0681 0.1567 0.197
Toxoplasma gondii aurora kinase 0.0524 0.1114 0.189
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0184 0.0133 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0221 0.024 0.0366
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Schistosoma mansoni tyrosine kinase 0.093 0.2285 0.5527
Schistosoma mansoni ephrin receptor 0.0182 0.0127 0.0268
Echinococcus granulosus unc 13 munc13 0.0173 0.0101 0.0101
Entamoeba histolytica hypothetical protein 0.0144 0.0018 0.0002
Loa Loa (eye worm) hypothetical protein 0.0206 0.0197 0.0248
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0281 0.0412 0.0412
Echinococcus multilocularis casein kinase I delta 0.0352 0.0619 0.085
Trichomonas vaginalis CAMK family protein kinase 0.0852 0.2061 0.3351
Brugia malayi Ras association domain family 1 isoform A 0.0163 0.0074 0.0093
Brugia malayi Fes/CIP4 homology domain containing protein 0.0345 0.0598 0.0752
Entamoeba histolytica protein kinase domain containing protein 0.0333 0.0564 0.0897
Schistosoma mansoni unc-13 (munc13) 0.0173 0.0101 0.0205
Onchocerca volvulus 0.0295 0.0454 0.088
Schistosoma mansoni cell adhesion molecule 0.0408 0.078 0.186
Brugia malayi Protein kinase domain containing protein 0.226 0.6119 0.7691
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0434 0.0855 0.2328
Loa Loa (eye worm) hypothetical protein 0.0214 0.0219 0.0275
Schistosoma mansoni tensin 0.0152 0.004 0.0058
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.016 0.0064 0.0078
Echinococcus multilocularis cyclin dependent kinase 1 0.0563 0.1225 0.1682
Entamoeba histolytica protein kinase, putative 0.2157 0.5824 0.9516
Trichomonas vaginalis AGC family protein kinase 0.0524 0.1114 0.1799
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Brugia malayi serine/threonine-protein kinase PAK 7 0.0727 0.17 0.2136
Echinococcus multilocularis protein tyrosine kinase 0.1446 0.3773 0.5179
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.0619 0.1467
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0866 0.2101 0.5788
Schistosoma mansoni protein kinase 0.1117 0.2824 0.684
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0215 0.0223 0.0223
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1094 0.2759 0.2759
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2036 0.331
Schistosoma mansoni serine/threonine protein kinase 0.0866 0.2101 0.5078
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0152 0.004 0.0058
Echinococcus multilocularis ephrin type A receptor 4 A 0.0339 0.0581 0.0797
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0259 0.0351 0.0441
Brugia malayi RhoGAP domain containing protein 0.0163 0.0074 0.0093
Echinococcus multilocularis casein kinase ii subunit alpha 0.0611 0.1366 0.1875
Loa Loa (eye worm) CDC7 protein kinase 0.0234 0.0277 0.0348
Trypanosoma brucei Casein kinase II 0.0611 0.1366 0.2212
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0597 0.1326 0.182
Trichomonas vaginalis CMGC family protein kinase 0.0234 0.0277 0.0426
Echinococcus multilocularis natriuretic peptide receptor 1 0.0143 0.0017 0.0023
Loa Loa (eye worm) protein kinase domain-containing protein 0.0484 0.0998 0.1254
Echinococcus granulosus ephrin type A receptor 4 A 0.0339 0.0581 0.0581
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.017 0.0373
Echinococcus granulosus natriuretic peptide receptor 1 0.0143 0.0017 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0048 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Loa Loa (eye worm) raf kinase 0.0163 0.0074 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0175 0.0106 0.0134
Brugia malayi serine/threonine kinase 12 0.0524 0.1114 0.1401
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0281 0.0412 0.0566
Echinococcus multilocularis tyrosine protein kinase Fyn 0.071 0.1651 0.2266
Echinococcus granulosus Protein kinase C brain isozyme 0.1365 0.3538 0.3538
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0413 0.0965
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0281 0.0414 0.052
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1079 0.2715 0.3412
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2884
Brugia malayi phosphoinositide-dependent protein kinase I 0.0267 0.0372 0.0468
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Toxoplasma gondii casein kinase I 0.0352 0.0619 0.1037
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus multilocularis epidermal growth factor receptor 0.1567 0.4122 0.5657
Trypanosoma brucei cdc2-related kinase 1 0.0563 0.1225 0.198
Schistosoma mansoni titin 0.0233 0.0276 0.0631
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Schistosoma mansoni tyrosine kinase 0.0214 0.0219 0.0492
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0413 0.0965
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2884
Echinococcus granulosus epidermal growth factor receptor 0.1074 0.2699 0.2699
Onchocerca volvulus 0.0164 0.0077 0.0121
Trypanosoma cruzi cdc2-related kinase 1 0.0563 0.1225 0.3356
Echinococcus granulosus dual specificity 0.0333 0.0564 0.0564
Trichomonas vaginalis STE family protein kinase 0.0281 0.0414 0.0651
Brugia malayi casein kinase 1, delta 0.0352 0.0619 0.0778
Trichomonas vaginalis CK1 family protein kinase 0.0352 0.0619 0.0987
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0315 0.0512 0.1205
Brugia malayi protein unc-22 0.0233 0.0276 0.0347
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0709 0.1648 0.1648
Giardia lamblia Kinase, CMGC GSK 0.0516 0.1091 0.3249
Schistosoma mansoni protein kinase C mu 0.0722 0.1686 0.4067
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0143 0.0017 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0434 0.0855 0.2043
Onchocerca volvulus 0.0295 0.0454 0.088
Schistosoma mansoni serine/threonine protein kinase 0.0709 0.1648 0.3975
Loa Loa (eye worm) hypothetical protein 0.0378 0.0694 0.0872
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Trichomonas vaginalis STE family protein kinase 0.0281 0.0414 0.0651
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0224 0.0249 0.0645
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus multilocularis 0.0152 0.004 0.0056
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0164 0.0077 0.0096
Loa Loa (eye worm) TK protein kinase 0.0143 0.0017 0.0021
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus multilocularis protein kinase 0.0143 0.0017 0.0023
Schistosoma mansoni diacylglycerol kinase theta 0.0163 0.0074 0.014
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0321 0.0528 0.088
Brugia malayi Protein kinase domain containing protein 0.0442 0.0879 0.1104
Schistosoma mansoni ste20-related kinase 0.0645 0.1462 0.3522
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0175 0.0106 0.0219
Schistosoma mansoni tyrosine kinase 0.0576 0.1264 0.3039
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0281 0.0413 0.11
Entamoeba histolytica serine/threonine protein kinase, putative 0.0154 0.0048 0.0052
Entamoeba histolytica hypothetical protein 0.0221 0.024 0.0366
Entamoeba histolytica protein kinase domain containing protein 0.0168 0.0087 0.0116
Plasmodium falciparum calcium-dependent protein kinase 2 0.0321 0.0528 0.1546
Echinococcus granulosus serine:threonine protein kinase 0.0367 0.066 0.066
Brugia malayi bone morphogenetic protein type 1 receptor 0.0222 0.0244 0.0306
Trypanosoma brucei rac serine-threonine kinase, putative 0.226 0.6119 1
Trypanosoma cruzi casein kinase, putative 0.0352 0.0619 0.1673
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0143 0.0017 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0321 0.0528 0.1546
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0087 0.0172
Toxoplasma gondii diacylglycerol kinase, putative 0.0163 0.0074 0.0099
Onchocerca volvulus 0.0152 0.004 0.0048
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0393 0.0736 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0233 0.0276 0.0347
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Mycobacterium ulcerans DNA gyrase subunit A 0.0238 0.029 0.1737
Schistosoma mansoni serine/threonine protein kinase 0.1391 0.3613 0.8761
Plasmodium vivax DNA gyrase subunit A, putative 0.0238 0.029 0.0828
Echinococcus multilocularis kinase suppressor of Ras 1 0.0143 0.0017 0.0023
Schistosoma mansoni hypothetical protein 0.0152 0.004 0.0058
Brugia malayi cyclin-dependent kinase 7 homolog 0.0205 0.0195 0.0245
Schistosoma mansoni nephrin 0.0175 0.0106 0.0219
Loa Loa (eye worm) IKK protein kinase 0.1602 0.4223 0.5308
Entamoeba histolytica casein kinase, putative 0.0611 0.1366 0.2212
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.075 0.1767 0.1767
Entamoeba histolytica protein kinase, putative 0.0986 0.2446 0.3981
Entamoeba histolytica protein kinase , putative 0.0524 0.1114 0.1799
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Schistosoma mansoni hypothetical protein 0.0269 0.038 0.0885
Echinococcus granulosus NDR protein kinase 0.0986 0.2446 0.2446
Onchocerca volvulus 0.0233 0.0276 0.0521
Echinococcus multilocularis FL cytokine receptor 0.0143 0.0017 0.0023
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.022 0.0238 0.038
Echinococcus granulosus neuroglian 0.0175 0.0106 0.0106
Echinococcus granulosus tyrosine protein kinase Src42A 0.071 0.1651 0.1651
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0245 0.031 0.031
Echinococcus granulosus TGF-beta receptor type-1 0.0197 0.0172 0.0172
Echinococcus granulosus tyrosine protein kinase pr2 0.0143 0.0017 0.0017
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0866 0.2101 0.3589
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0497 0.1036 0.4889
Trypanosoma cruzi casein kinase, putative 0.0352 0.0619 0.1673
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0321 0.0528 0.1546
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0321 0.0528 0.0663
Brugia malayi serine/threonine-protein kinase 6 0.0524 0.1114 0.1401
Brugia malayi hypothetical protein 0.0143 0.0017 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0497 0.1036 0.167
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0554 0.1201 0.151
Trichomonas vaginalis CMGC family protein kinase 0.0434 0.0855 0.1374
Schistosoma mansoni protein kinase 0.1117 0.2824 0.684
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0321 0.0528 0.1546
Brugia malayi hypothetical protein 0.0295 0.0454 0.0571
Brugia malayi Pleckstrin Homology Domain 0.0266 0.0369 0.0464
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0175 0.0106 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Trypanosoma cruzi casein kinase II, putative 0.0611 0.1366 0.3748
Echinococcus granulosus Diacylglycerol kinase theta 0.0163 0.0074 0.0074
Entamoeba histolytica protein kinase domain containing protein 0.0516 0.1091 0.176
Plasmodium falciparum NIMA related kinase 4 0.0154 0.0048 0.0096
Echinococcus multilocularis tensin 0.0152 0.004 0.0056
Trichomonas vaginalis STE family protein kinase 0.0214 0.0221 0.0335
Schistosoma mansoni serine/threonine kinase 0.0986 0.2446 0.5918
Echinococcus multilocularis PAK box P21 Rho binding 0.0214 0.0221 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0866 0.2101 0.5078
Loa Loa (eye worm) TK/ACK protein kinase 0.0143 0.0017 0.0021
Trypanosoma brucei cdc2-related kinase 3 0.0563 0.1225 0.198
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0215 0.0223 0.0503
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0434 0.0855 0.2328
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0439 0.0869 0.0869
Trypanosoma cruzi aurora B kinase, putative 0.0524 0.1114 0.3048
Echinococcus granulosus kinase suppressor of Ras 1 0.0143 0.0017 0.0017
Schistosoma mansoni signal transduction protein lnk-related 0.0152 0.004 0.0058
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0276 0.04 0.0629
Echinococcus granulosus tyrosine kinase 0.0143 0.0017 0.0017
Entamoeba histolytica PH domain containing protein kinase, putative 0.0221 0.024 0.0366
Entamoeba histolytica protein kinase, putative 0.0516 0.1091 0.176
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0143 0.0017 0.0017
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Loa Loa (eye worm) RGC/RGC protein kinase 0.0143 0.0017 0.0021
Entamoeba histolytica PH domain containing protein kinase, putative 0.037 0.0669 0.1069
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0175 0.0106 0.0146
Giardia lamblia Kinase, CMGC MAPK 0.0382 0.0706 0.2085
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0175 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0182 0.0128 0.0161
Echinococcus multilocularis calcium activated potassium channel 0.0388 0.0722 0.099
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0524 0.1114 0.1799
Brugia malayi Protein kinase domain containing protein 0.0295 0.0454 0.0571
Schistosoma mansoni protein kinase 0.0197 0.0172 0.0377
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0281 0.0412 0.0566
Echinococcus multilocularis SH2 motif 0.0152 0.004 0.0056
Schistosoma mansoni vesicular amine transporter 0.031 0.0498 0.1172
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0722 0.1686 0.2119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0129 0.0162
Toxoplasma gondii NEK kinase 0.0154 0.0048 0.0055
Loa Loa (eye worm) hypothetical protein 0.0935 0.2298 0.2889
Schistosoma mansoni hypothetical protein 0.032 0.0527 0.1244
Echinococcus multilocularis epidermal growth factor receptor 0.1074 0.2699 0.3705
Leishmania major protein kinase, putative 0.0321 0.0528 0.2452
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0186 0.0138 0.0174
Echinococcus granulosus c src tyrosine kinase 0.0408 0.0779 0.0779
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0234 0.0278 0.0278
Echinococcus granulosus tyrosine protein kinase Fyn 0.071 0.1651 0.1651
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0234 0.0279 0.0279
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0516 0.1091 0.185
Echinococcus granulosus neuroglian 0.0387 0.0719 0.0719
Echinococcus multilocularis Diacylglycerol kinase theta 0.0163 0.0074 0.0102
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0143 0.0017 0.0021
Leishmania major protein kinase, putative 0.0154 0.0048 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0333 0.0564 0.0897
Brugia malayi SH2 domain containing protein 0.091 0.2227 0.2798
Brugia malayi Protein kinase domain containing protein 0.0262 0.0359 0.0451
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0152 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.0488 0.1148
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Echinococcus granulosus protein kinase c epsilon type 0.1307 0.3372 0.3372
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0516 0.1091 0.1091
Echinococcus multilocularis serine:threonine protein kinase N2 0.1391 0.3613 0.4959
Plasmodium falciparum DNA gyrase subunit B 0.0393 0.0736 0.2175
Loa Loa (eye worm) hypothetical protein 0.0348 0.0608 0.0764
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0462 0.0936 0.1176
Echinococcus multilocularis Immunoglobulin 0.031 0.0498 0.0683
Trichomonas vaginalis STE family protein kinase 0.0281 0.0412 0.0648
Giardia lamblia Kinase, AGC AKT 0.0468 0.0952 0.2829
Trichomonas vaginalis STE family protein kinase 0.0281 0.0412 0.0648
Schistosoma mansoni protein kinase 0.0442 0.0879 0.21
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0197 0.017 0.0214
Echinococcus multilocularis protein kinase c iota type 0.1403 0.3648 0.5007
Echinococcus granulosus titin 0.0233 0.0276 0.0276
Echinococcus granulosus tyrosine protein kinase Srms 0.1121 0.2836 0.2836
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0143 0.0017 0.0021
Brugia malayi Protein kinase domain containing protein 0.022 0.0238 0.0299
Echinococcus multilocularis c src tyrosine kinase 0.0408 0.0779 0.1069
Echinococcus multilocularis tyrosine protein kinase Src42A 0.071 0.1651 0.2266
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1094 0.2759 0.3787
Brugia malayi Protein kinase domain containing protein 0.0554 0.1201 0.151
Echinococcus granulosus protein kinase 0.0143 0.0017 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0611 0.1366 0.2212
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0781 0.1856 0.2333
Brugia malayi Protein kinase domain containing protein 0.1285 0.3309 0.4159
Schistosoma mansoni tensin 0.0152 0.004 0.0058
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0333 0.0564 0.0709
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0175 0.0106 0.0146
Echinococcus multilocularis Rac GTPase activating protein 1 0.0163 0.0074 0.0102
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Schistosoma mansoni protein kinase C mu 0.0163 0.0074 0.014
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0267 0.0372 0.0468
Loa Loa (eye worm) hypothetical protein 0.0348 0.0608 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Schistosoma mansoni GTPase activating protein 0.0152 0.004 0.0058
Entamoeba histolytica protein kinase 2, putative 0.129 0.3323 0.5417
Brugia malayi Cam kinase protein 1 0.0321 0.0528 0.0663
Brugia malayi cyclin-dependent kinase 9 0.0168 0.0087 0.011
Loa Loa (eye worm) serine/threonine protein kinase 0.0143 0.0017 0.0021
Echinococcus granulosus protein kinase c iota type 0.1403 0.3648 0.3648
Brugia malayi Protein kinase domain containing protein 0.0434 0.0855 0.1075
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0262 0.036 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0372 0.0866
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2162 0.5836 0.7336
Brugia malayi hypothetical protein 0.032 0.0527 0.0663
Echinococcus multilocularis heat shock protein 70 0.0143 0.0017 0.0023
Brugia malayi Protein kinase domain containing protein 0.0815 0.1954 0.2456
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Echinococcus granulosus cGMP dependent protein kinase 0.0324 0.0538 0.0538
Onchocerca volvulus 0.1011 0.252 0.5033
Loa Loa (eye worm) SH2 domain-containing protein 0.0152 0.004 0.0051
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Plasmodium falciparum cGMP-dependent protein kinase 0.0324 0.0538 0.1578
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0434 0.0855 0.2328
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.129 0.3323 0.3323
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0844 0.2036 0.2036
Brugia malayi Protein kinase domain containing protein 0.1186 0.3024 0.3801
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0264 0.0365 0.0459
Echinococcus granulosus receptor type guanylyl cyclase 0.0143 0.0017 0.0017
Plasmodium vivax casein kinase 1, putative 0.0352 0.0619 0.1822
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0516 0.1091 0.2617
Echinococcus multilocularis dual specificity mitogen activated protein 0.0281 0.0414 0.0568
Echinococcus multilocularis roundabout 2 0.0175 0.0106 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.1365 0.3538 0.8578
Trichomonas vaginalis CAMK family protein kinase 0.0404 0.0768 0.1231
Echinococcus granulosus mitogen activated protein kinase 11 0.0642 0.1456 0.1456
Loa Loa (eye worm) hypothetical protein 0.0196 0.0167 0.021
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.022 0.0238 0.0613
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0382 0.0706 0.1914
Plasmodium falciparum calcium-dependent protein kinase 5 0.0321 0.0528 0.1546
Echinococcus granulosus tyrosine protein kinase HCK 0.0446 0.0888 0.0888
Echinococcus multilocularis expressed conserved protein 0.0324 0.0538 0.0739
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0442 0.0879 0.1104
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0152 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.1335 0.3453 0.8371
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0143 0.0017 0.0021
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0986 0.2446 0.2446
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0413 0.0965
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0681 0.1567 0.197
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Echinococcus granulosus nervana 2 0.1171 0.2981 0.2981
Brugia malayi tRNA modification GTPase TrmE family protein 0.0152 0.004 0.0051
Entamoeba histolytica hypothetical protein 0.0215 0.0223 0.0338
Brugia malayi Protein kinase domain containing protein 0.0484 0.0998 0.1254
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Schistosoma mansoni serine/threonine protein kinase 0.0781 0.1856 0.4482
Echinococcus granulosus tyrosine protein kinase Blk 0.0597 0.1326 0.1326
Echinococcus multilocularis 0.0436 0.0861 0.1182
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0281 0.0413 0.1901
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0281 0.0413 0.1901
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.046 0.0931 0.1277
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.032 0.0527 0.0724
Trichomonas vaginalis CAMK family protein kinase 0.0285 0.0424 0.0668
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0221 0.024 0.0366
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0321 0.0528 0.0663
Schistosoma mansoni suppressor of cytokine signaling 0.0152 0.004 0.0058
Brugia malayi Immunoglobulin I-set domain containing protein 0.2162 0.5836 0.7336
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1074 0.2699 0.2699
Loa Loa (eye worm) hypothetical protein 0.0588 0.1299 0.1633
Echinococcus granulosus tyrosine protein kinase csk 0.0143 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0486 0.1004 0.1261
Schistosoma mansoni protein kinase 0.0214 0.0221 0.0498
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.1171 0.2981 0.4091
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0524 0.1114 0.332
Schistosoma mansoni protein kinase 0.0748 0.1761 0.4249
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0152 0.004 0.0051
Schistosoma mansoni Neurotrimin precursor (hNT) 0.031 0.0498 0.1172
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0238 0.0538
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Echinococcus multilocularis rac serine:threonine kinase 0.1392 0.3618 0.4966
Schistosoma mansoni serine/threonine protein kinase 0.0844 0.2036 0.492
Loa Loa (eye worm) SH2 domain-containing protein 0.0152 0.004 0.0051
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Schistosoma mansoni serine/threonine protein kinase 0.1223 0.3129 0.7581
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0143 0.0017 0.0021
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.032 0.0527 0.0837
Echinococcus multilocularis integrin linked protein kinase 0.0143 0.0017 0.0023
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0352 0.0619 0.0778
Onchocerca volvulus Serine\/threonine kinase homolog 0.0844 0.2036 0.4061
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0234 0.0279 0.0382
Trypanosoma cruzi p21-activated kinase 3, putative 0.0185 0.0136 0.0331
Brugia malayi diacylglycerol kinase 0.0163 0.0074 0.0093
Onchocerca volvulus 0.0295 0.0454 0.088
Echinococcus granulosus serine threonine protein kinase nrc 0.129 0.3323 0.3323
Trypanosoma cruzi cdc2-related kinase 3 0.0563 0.1225 0.3356
Echinococcus granulosus dual specificity 0.0333 0.0564 0.0564
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0221 0.024 0.062
Loa Loa (eye worm) AUR protein kinase 0.0524 0.1114 0.1401
Brugia malayi putative serine/threonine kinase SADA gamma 0.0281 0.0413 0.0519
Entamoeba histolytica protein kinase, putative 0.033 0.0554 0.0881
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0866 0.2101 0.5788
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.032 0.0527 0.1244
Schistosoma mansoni vam6/vps39 related 0.032 0.0527 0.1244
Echinococcus granulosus twitchin 0.0505 0.106 0.106
Echinococcus multilocularis mitogen activated protein kinase 14 0.0642 0.1456 0.1998
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1223 0.3129 0.3932
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0152 0.004 0.0048
Echinococcus granulosus serine/threonine protein kinase 0.1392 0.3618 0.3618
Entamoeba histolytica hypothetical protein 0.0497 0.1036 0.167
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0434 0.0855 0.1374
Brugia malayi Stress-activated protein kinase jnk-1 0.1079 0.2715 0.3412
Echinococcus granulosus casein kinase I alpha 0.0352 0.0619 0.0619
Echinococcus multilocularis serine:threonine protein kinase 38 0.0986 0.2446 0.3357
Echinococcus granulosus roundabout 2 0.0485 0.1001 0.1001
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0152 0.004 0.0058
Brugia malayi Protein kinase domain containing protein 0.0497 0.1036 0.1302
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0352 0.0619 0.0778
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus multilocularis pdz domain containing protein 0.0138 0.0001 0.0002
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0943 0.2321 0.3186
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0681
Echinococcus multilocularis neuroglian 0.0387 0.0719 0.0987
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0722 0.1717
Loa Loa (eye worm) hypothetical protein 0.0369 0.0668 0.084
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0234 0.0277 0.0724
Plasmodium falciparum serine/threonine protein kinase, putative 0.0524 0.1114 0.332
Echinococcus granulosus casein kinase I delta 0.0352 0.0619 0.0619
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0143 0.0017 0.0021
Echinococcus granulosus raf serine:threonine protein kinase 0.0307 0.0488 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Brugia malayi integrin-linked kinase 0.0143 0.0017 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0706 0.1129
Echinococcus granulosus tyrosine protein kinase Lyn 0.0829 0.1992 0.1992
Trypanosoma cruzi NIMA-related kinase, putative 0.0221 0.024 0.062
Schistosoma mansoni tyrosine kinase 0.0988 0.2451 0.593
Schistosoma mansoni serine/threonine protein kinase 0.0866 0.2101 0.5078
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0221 0.024 0.0366
Onchocerca volvulus 0.0295 0.0454 0.088
Trichomonas vaginalis CAMK family protein kinase 0.0554 0.1201 0.1941
Echinococcus granulosus cGMP dependent protein kinase 1 0.0324 0.0538 0.0538
Schistosoma mansoni rap gtpase-activating protein 0.032 0.0527 0.1244
Loa Loa (eye worm) hypothetical protein 0.031 0.0498 0.0626
Echinococcus multilocularis tyrosine kinase 0.0143 0.0017 0.0023
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Echinococcus multilocularis death associated protein kinase 1 0.2664 0.7285 1
Onchocerca volvulus 0.0295 0.0454 0.088
Echinococcus multilocularis nervana 2 0.1171 0.2981 0.4091
Trypanosoma cruzi cdc2-related kinase 1 0.0563 0.1225 0.3356
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0238 0.029 0.0471
Echinococcus multilocularis raf serine:threonine protein kinase 0.0307 0.0488 0.0669
Brugia malayi RhoGEF domain containing protein 0.0163 0.0074 0.0093
Echinococcus granulosus CDC7 cell division cycle 7 0.0234 0.0277 0.0277
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0152 0.004 0.0056
Echinococcus multilocularis roundabout 2 0.0175 0.0106 0.0146
Echinococcus granulosus roundabout 2 0.0175 0.0106 0.0106
Brugia malayi Serine/threonine-protein kinase SULU 0.0709 0.1648 0.2072
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0434 0.0854 0.2533
Brugia malayi p70 ribosomal S6 kinase beta 0.2157 0.5824 0.7319
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0154 0.0048 0.0152
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0262 0.0359 0.0451
Loa Loa (eye worm) hypothetical protein 0.0391 0.0731 0.0918
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2101
Echinococcus multilocularis serine:threonine protein kinase 0.0367 0.066 0.0906
Echinococcus granulosus SH2 domain containing protein 7 0.0152 0.004 0.004
Trichomonas vaginalis STE family protein kinase 0.0434 0.0854 0.1372
Onchocerca volvulus 0.0152 0.004 0.0048
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0143 0.0017 0.0023
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0384 0.0711 0.0711
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0434 0.0855 0.1374
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0516 0.1091 0.1371
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.032 0.0527 0.1418
Echinococcus granulosus signal transduction protein lnk realted 0.0152 0.004 0.004
Entamoeba histolytica SH2-protein kinase domain containing protein 0.027 0.0382 0.0599
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0285 0.0424 0.0583
Giardia lamblia Kinase, STE STE20 0.0281 0.0412 0.1197
Echinococcus multilocularis casein kinase I alpha 0.0352 0.0619 0.085
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0611 0.1366 0.4083
Schistosoma mansoni serine/threonine protein kinase 0.0812 0.1944 0.4695
Schistosoma mansoni kinase 0.09 0.2199 0.5316
Onchocerca volvulus 0.0516 0.1091 0.216
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0497 0.1036 0.1302
Brugia malayi Fibronectin type III domain containing protein 0.0348 0.0608 0.0764
Echinococcus granulosus serine:threonine kinase SAD 1 0.0281 0.0413 0.0413
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0681 0.1567 0.1567
Brugia malayi Temporarily assigned gene name protein 59 0.0394 0.074 0.093
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Mycobacterium ulcerans DNA gyrase subunit B 0.0393 0.0736 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0636 0.1437 0.1437
Schistosoma mansoni nephrin 0.0425 0.0829 0.1978
Loa Loa (eye worm) TK/ALK protein kinase 0.1186 0.3023 0.38
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0611 0.1366 0.1717
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0143 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0321 0.0528 0.0663
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0136 0.029
Echinococcus multilocularis tyrosine protein kinase 0.0629 0.1417 0.1945
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0281 0.0412 0.0412
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0516 0.1091 0.1371
Trypanosoma brucei aurora B kinase 0.0524 0.1114 0.1799
Brugia malayi Temporarily assigned gene name protein 59 0.032 0.0527 0.0663
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0152 0.004 0.0048
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0524 0.1114 0.1799
Echinococcus multilocularis dual specificity 0.0333 0.0564 0.0774
Echinococcus multilocularis cyclin dependent kinase 9 0.0168 0.0087 0.012
Brugia malayi Variant SH3 domain containing protein 0.0315 0.0512 0.0643
Echinococcus multilocularis protein kinase 0.0143 0.0017 0.0023
Schistosoma mansoni protein kinase 0.0281 0.0412 0.0964
Echinococcus granulosus SH2 domain containing adapter protein F 0.0152 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0262 0.0358 0.0949
Echinococcus multilocularis NCK adaptor protein 0.027 0.0382 0.0524
Trypanosoma cruzi casein kinase, putative 0.0352 0.0619 0.1673
Schistosoma mansoni protein kinase 0.0737 0.1729 0.4171
Schistosoma mansoni serine/threonine protein kinase 0.0681 0.1567 0.3777
Brugia malayi cytokine inducible SH2-containing protein 5 0.0152 0.004 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.075 0.1767 0.4265
Echinococcus multilocularis expressed protein 0.022 0.0238 0.0326
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0524 0.1114 0.153
Loa Loa (eye worm) hypothetical protein 0.0604 0.1344 0.169
Echinococcus granulosus titin 0.0233 0.0276 0.0276
Schistosoma mansoni protein kinase 0.0262 0.0358 0.0832
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0143 0.0017 0.0023
Entamoeba histolytica casein kinase, putative 0.0352 0.0619 0.0987
Echinococcus multilocularis CDC7 cell division cycle 7 0.0234 0.0277 0.038
Entamoeba histolytica protein kinase domain containing protein 0.0524 0.1114 0.1799
Echinococcus multilocularis tyrosine protein kinase csk 0.0143 0.0017 0.0023
Echinococcus multilocularis tyrosine protein kinase Src42A 0.046 0.0929 0.1275
Schistosoma mansoni serine/threonine protein kinase 0.0462 0.0936 0.2239
Giardia lamblia Kinase, CMGC DYRK 0.0333 0.0564 0.1656
Giardia lamblia Kinase, STE STE20 0.0276 0.04 0.1161
Schistosoma mansoni rac gtpase activating protein 0.0163 0.0074 0.014
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0382 0.0706 0.1914
Loa Loa (eye worm) RGC/RGC protein kinase 0.0143 0.0017 0.0021
Plasmodium falciparum protein serine/threonine kinase-1 0.0434 0.0855 0.2537
Echinococcus granulosus tyrosine protein kinase csk 0.0143 0.0017 0.0017
Giardia lamblia Kinase, STE STE20 0.0281 0.0414 0.1201
Brugia malayi Receptor family ligand binding region containing protein 0.0143 0.0017 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0158 0.0057 0.0067
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0986 0.2446 0.3357
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0185 0.0136 0.0171
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.031 0.0498 0.1172
Trichomonas vaginalis STE family protein kinase 0.0281 0.0412 0.0648
Brugia malayi Tyrosine-protein kinase abl-1 0.04 0.0756 0.0951
Trypanosoma cruzi Protein kinase B 0.1392 0.3618 1
Trichomonas vaginalis AGC family protein kinase 0.113 0.2861 0.466
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1267 0.3257 0.4094
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0524 0.1114 0.1799
Schistosoma mansoni tyrosine kinase 0.1074 0.2699 0.6535
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0781 0.1856 0.2548
Brugia malayi Protein kinase domain containing protein 0.0186 0.0138 0.0174
Brugia malayi Protein kinase domain containing protein 0.0295 0.0454 0.0571
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0315 0.0512 0.1205
Plasmodium falciparum casein kinase 2, alpha subunit 0.0611 0.1366 0.4083
Onchocerca volvulus 0.0173 0.0101 0.0169
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Brugia malayi SH2 domain containing protein 0.0295 0.0454 0.0571
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0372 0.0583
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0563 0.1225 0.154
Brugia malayi Tensin 0.0152 0.004 0.0051
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0281 0.0414 0.1102
Toxoplasma gondii NEK kinase 0.0154 0.0048 0.0055
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0631 0.1423 0.1423
Loa Loa (eye worm) TK/ABL protein kinase 0.0943 0.2321 0.2918
Trichomonas vaginalis TKL family protein kinase 0.0146 0.0023 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Leishmania major protein kinase, putative 0.0434 0.0855 0.4023
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0281 0.0414 0.052
Loa Loa (eye worm) AGC/NDR protein kinase 0.0986 0.2446 0.3074
Trypanosoma brucei NIMA-related protein kinase 0.0154 0.0048 0.0052
Brugia malayi serine/threonine protein kinase 6 0.0524 0.1114 0.1401
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0264 0.0365 0.0459
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0748 0.1759 0.2415
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2101
Giardia lamblia Kinase, CMGC CDK 0.0563 0.1225 0.3656
Loa Loa (eye worm) TK protein kinase 0.0597 0.1326 0.1666
Echinococcus granulosus dual specificity 0.0497 0.1036 0.1036
Entamoeba histolytica diacylglycerol kinase, putative 0.0163 0.0074 0.0094
Echinococcus multilocularis tyrosine kinase 0.0295 0.0454 0.0623
Entamoeba histolytica protein kinase domain containing protein 0.0516 0.1091 0.176
Leishmania major serine/threonine-protein kinase, putative 0.0154 0.0048 0.0152
Echinococcus multilocularis dual specificity 0.0333 0.0564 0.0774
Echinococcus granulosus geminin 0.0172 0.01 0.01
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0516 0.1091 0.2983
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1053 0.264 0.264
Schistosoma mansoni serine/threonine protein kinase 0.1011 0.252 0.6098
Echinococcus granulosus SH2 motif 0.0152 0.004 0.004
Plasmodium falciparum calcium-dependent protein kinase 4 0.0321 0.0528 0.1546
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0221 0.024 0.062
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0462 0.0936 0.0936
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0384 0.0711 0.0976
Schistosoma mansoni ephrin receptor 0.0339 0.0581 0.1375
Brugia malayi Protein kinase domain containing protein 0.0177 0.0114 0.0143
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0352 0.0619 0.1673
Brugia malayi Protein kinase domain containing protein 0.0986 0.2446 0.3074
Schistosoma mansoni hypothetical protein 0.0152 0.004 0.0058
Echinococcus granulosus TGF beta receptor type 1 0.0197 0.0172 0.0172
Echinococcus multilocularis hypothetical protein 0.0269 0.038 0.0521
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0844 0.2036 0.2559
Echinococcus granulosus retinal guanylyl cyclase 2 0.0143 0.0017 0.0017
Brugia malayi Protein kinase domain containing protein 0.0267 0.0372 0.0468
Echinococcus granulosus Immunoglobulin 0.031 0.0498 0.0498
Brugia malayi Furin-like cysteine rich region family protein 0.1567 0.4122 0.518
Echinococcus granulosus Rac GTPase activating protein 1 0.0163 0.0074 0.0074
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0152 0.004 0.0056
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0215 0.0223 0.0306
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0281 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0348 0.0608 0.0764
Trypanosoma cruzi casein kinase, putative 0.0352 0.0619 0.1673
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0154 0.0048 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.0722 0.1717
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0636 0.1437 0.1972
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0185 0.0136 0.0331
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2036 0.331
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Schistosoma mansoni growth factor receptor-bound protein 0.027 0.0382 0.089
Brugia malayi Protein kinase domain containing protein 0.2897 0.7956 1
Echinococcus granulosus rho-associated protein kinase 1 0.1011 0.252 0.252
Brugia malayi Egg laying defective protein 4 0.0324 0.0538 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.075 0.1767 0.4265
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0154 0.0048 0.0096
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.016 0.0064 0.0078
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.0017 0.0017
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0781 0.1856 0.2333
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Echinococcus granulosus integrin linked protein kinase 0.0143 0.0017 0.0017
Plasmodium vivax protein kinase Crk2 0.0563 0.1225 0.3656
Plasmodium falciparum protein kinase, putative 0.0262 0.0358 0.1034
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.0023 0.0011
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0844 0.2036 0.2795
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1223 0.3129 0.4294
Echinococcus granulosus tyrosine protein kinase ABL1 0.0943 0.2321 0.2321
Echinococcus multilocularis serine:threonine protein kinase N2 0.1134 0.2874 0.3945
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0516 0.1091 0.1497
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1528 0.401 0.504
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2036 0.331
Echinococcus multilocularis cyclin dependent kinase 0.0563 0.1225 0.1682
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0333 0.0564 0.0897
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1079 0.2715 0.3726
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1053 0.264 0.3624
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0748 0.1759 0.1759
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0333 0.0564 0.152
Trichomonas vaginalis STE family protein kinase 0.0154 0.0048 0.0052
Brugia malayi Casein kinase II, alpha chain 0.0611 0.1366 0.1717
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.1307 0.3372 0.4238
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.071 0.1651 0.2266
Schistosoma mansoni protein kinase 0.0737 0.1729 0.4171
Echinococcus granulosus casein kinase ii subunit alpha 0.0611 0.1366 0.1366
Plasmodium vivax serine/threonine kinase-1, putative 0.0434 0.0855 0.2537
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0321 0.0528 0.0724
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0263 0.0363 0.0456
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0727 0.17 0.2136
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0315 0.0512 0.0702
Brugia malayi cell division control protein 2 homolog 0.0563 0.1225 0.154
Echinococcus granulosus cyclin dependent kinase 9 0.0168 0.0087 0.0087
Schistosoma mansoni tyrosine kinase 0.0408 0.0779 0.1857
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0281 0.0413 0.0567
Echinococcus granulosus Glutaredoxin protein 5 0.1171 0.2981 0.2981
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.129 0.3323 1
Echinococcus multilocularis casein kinase I delta 0.0352 0.0619 0.085
Schistosoma mansoni serine/threonine-protein kinase 0.1392 0.3618 0.8773
Entamoeba histolytica protein kinase, putative 0.0221 0.024 0.0366
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1323 0.3419 0.4693
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0234 0.0278 0.0382
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Entamoeba histolytica protein kinase, putative 0.0333 0.0564 0.0897
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0281 0.0414 0.1905
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.075 0.1767 0.2426
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0998 0.239
Echinococcus multilocularis tyrosine protein kinase pr2 0.0143 0.0017 0.0023
Brugia malayi protein kinase C II. 0.1307 0.3372 0.4238
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0185 0.0136 0.0171
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0333 0.0564 0.0709
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0166 0.0363
Echinococcus granulosus retinal guanylyl cyclase 2 0.0143 0.0017 0.0017
Plasmodium falciparum serine/threonine protein kinase 0.022 0.0238 0.0668
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus multilocularis mitogen activated protein kinase 0.0382 0.0706 0.0969
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0524 0.1114 0.1799
Echinococcus multilocularis 0.0428 0.0837 0.1148
Schistosoma mansoni tyrosine kinase 0.1567 0.4122 1
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.066 0.1054
Trichomonas vaginalis CMGC family protein kinase 0.0563 0.1225 0.198
Trichomonas vaginalis AGC family protein kinase 0.0434 0.0854 0.1372
Echinococcus granulosus suppressor of cytokine signaling 6 0.0152 0.004 0.004
Giardia lamblia Kinase, CMGC CK2 0.0611 0.1366 0.4083
Loa Loa (eye worm) SRC-1 0.071 0.1651 0.2075
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.129 0.3323 0.456
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0382 0.0706 0.1914
Brugia malayi Protein kinase domain containing protein 0.0295 0.0454 0.0571
Schistosoma mansoni protein kinase 0.0352 0.0619 0.1467
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Schistosoma mansoni serine/threonine protein kinase 0.0636 0.1437 0.346
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.096 0.2372 0.2982
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0382 0.0706 0.3307
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0262 0.0358 0.056
Trypanosoma cruzi casein kinase, putative 0.0352 0.0619 0.1673
Entamoeba histolytica cell division protein kinase 2, putative 0.0563 0.1225 0.198
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0833 0.2004 0.2519
Schistosoma mansoni cell adhesion molecule 0.0175 0.0106 0.0219
Brugia malayi Protein kinase domain containing protein 0.0629 0.1417 0.1781
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0796 0.19 0.2388
Echinococcus granulosus tyrosine protein kinase Fyn 0.071 0.1651 0.1651
Echinococcus multilocularis TGF beta receptor type 1 0.0197 0.0172 0.0236
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0497 0.1036 0.283
Loa Loa (eye worm) hypothetical protein 0.0266 0.0369 0.0464
Echinococcus multilocularis SH2 domain containing protein 7 0.0152 0.004 0.0056
Schistosoma mansoni protein kinase 0.1117 0.2824 0.684
Schistosoma mansoni suppressor of cytokine signaling 0.0152 0.004 0.0058
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0986 0.2446 0.3357
Loa Loa (eye worm) hypothetical protein 0.0173 0.0101 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0434 0.0855 0.2043
Echinococcus multilocularis protein kinase c eta type 0.0163 0.0074 0.0102
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Loa Loa (eye worm) TK protein kinase 0.0446 0.0888 0.1117
Schistosoma mansoni tyrosine kinase 0.1446 0.3773 0.9152
Plasmodium falciparum calcium-dependent protein kinase 1 0.0321 0.0528 0.1546
Brugia malayi Protein kinase domain containing protein 0.0295 0.0454 0.0571
Loa Loa (eye worm) hypothetical protein 0.0163 0.0074 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus multilocularis protein kinase shaggy 0.0516 0.1091 0.1497
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0803 0.1918 0.241
Loa Loa (eye worm) hypothetical protein 0.0751 0.177 0.2225
Trichomonas vaginalis AGC family protein kinase 0.0275 0.0397 0.0624
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0434 0.0854 0.1442
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0516 0.1091 0.5153
Echinococcus multilocularis myosin iiia 0.0276 0.04 0.055
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0143 0.0017 0.0023
Schistosoma mansoni tyrosine kinase 0.093 0.2285 0.5527
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.022 0.0238 0.0362
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0152 0.004 0.0056
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0281 0.0413 0.0649
Schistosoma mansoni tyrosine kinase 0.0239 0.0293 0.0674
Echinococcus granulosus serine:threonine protein kinase 3 0.0803 0.1918 0.1918
Echinococcus multilocularis tyrosine protein kinase Srms 0.0597 0.1326 0.182
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0866 0.2101 0.6305
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0597 0.1326 0.1326
Loa Loa (eye worm) CAMK protein kinase 0.0233 0.0276 0.0347
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Echinococcus multilocularis tyrosine protein kinase Src64B 0.071 0.1651 0.2266
Loa Loa (eye worm) hypothetical protein 0.0447 0.0891 0.112
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Plasmodium falciparum glycogen synthase kinase 3 0.0516 0.1091 0.3249
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0152 0.004 0.004
Entamoeba histolytica tyrosin kinase, putative 0.0158 0.0057 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0048 0.0052
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus multilocularis roundabout 2 0.0485 0.1001 0.1374
Loa Loa (eye worm) TK/CSK protein kinase 0.0143 0.0017 0.0021
Echinococcus granulosus aurora kinase A 0.0524 0.1114 0.1114
Loa Loa (eye worm) hypothetical protein 0.032 0.0527 0.0663
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0756 0.1783 0.1783
Schistosoma mansoni protein kinase 0.0428 0.0837 0.1998
Echinococcus granulosus protein tyrosine kinase 0.1446 0.3773 0.3773
Onchocerca volvulus 0.0152 0.004 0.0048
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0737 0.1729 0.2373
Giardia lamblia Kinase, CMGC GSK 0.0516 0.1091 0.3249
Entamoeba histolytica protein kinase, putative 0.0317 0.0517 0.0819
Entamoeba histolytica PH domain containing protein kinase, putative 0.0969 0.2396 0.39
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0439 0.0869 0.1193
Schistosoma mansoni serine/threonine protein kinase 0.1079 0.2715 0.6572
Entamoeba histolytica serine/threonine protein kinase, putative 0.0844 0.2036 0.331
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.032 0.0527 0.0527
Loa Loa (eye worm) AGC/AKT protein kinase 0.226 0.6119 0.7691
Brugia malayi Protein kinase domain containing protein 0.1602 0.4223 0.5308
Entamoeba histolytica protein kinase, putative 0.0524 0.1114 0.1799
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0154 0.0048 0.0096
Brugia malayi Sex muscle abnormal protein 5 0.0264 0.0365 0.0459
Giardia lamblia Kinase, CAMK CAMKL 0.029 0.0438 0.1274
Echinococcus multilocularis tyrosine protein kinase Abl 0.0655 0.1493 0.2049
Loa Loa (eye worm) hypothetical protein 0.0162 0.0071 0.0089
Loa Loa (eye worm) hypothetical protein 0.0254 0.0336 0.0422
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0756 0.1783 0.2447
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.1027 0.2565 0.3224
Echinococcus granulosus RNA directed DNA polymerase 0.0206 0.0197 0.0197
Brugia malayi Protein kinase domain containing protein 0.0645 0.1464 0.184
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0199 0.0178 0.0277
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0149 0.0033 0.0033
Echinococcus granulosus serine:threonine protein kinase 0.0367 0.066 0.066
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0145 0.002 0.0006
Echinococcus granulosus serine:threonine protein kinase N2 0.1391 0.3613 0.3613
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0324 0.0538 0.0739
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0382 0.0706 0.1187
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus granulosus hypothetical protein 0.0152 0.004 0.004
Plasmodium vivax glycogen synthase kinase 3, putative 0.0516 0.1091 0.3249
Entamoeba histolytica protein kinase, putative 0.0267 0.0372 0.0583
Echinococcus granulosus cyclin dependent kinase 9 0.0177 0.0112 0.0112
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.0706 0.1129
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0497 0.1036 0.167
Loa Loa (eye worm) hypothetical protein 0.0766 0.1813 0.2278
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0315 0.0512 0.0643
Loa Loa (eye worm) TK/EGFR protein kinase 0.1567 0.4122 0.518
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.129 0.3323 1
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.0538 0.1271
Schistosoma mansoni protein kinase 0.0281 0.0412 0.0964
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0221 0.024 0.062
Onchocerca volvulus 0.0152 0.004 0.0048
Brugia malayi map kinase activated protein kinase protein 2 0.1223 0.3129 0.3932
Echinococcus granulosus cyclin dependent kinase 5 0.0563 0.1225 0.1225
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Brugia malayi Protein kinase domain containing protein 0.0367 0.066 0.083
Loa Loa (eye worm) AUR protein kinase 0.0524 0.1114 0.1401
Loa Loa (eye worm) STAT protein 0.0152 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0163 0.0074 0.0093
Echinococcus multilocularis 0.0316 0.0514 0.0705
Trichomonas vaginalis CMGC family protein kinase 0.0333 0.0564 0.0897
Loa Loa (eye worm) hypothetical protein 0.1574 0.4142 0.5206
Brugia malayi ephrin receptor 1 precursor 0.0236 0.0283 0.0355
Echinococcus granulosus pdz domain containing protein 0.0138 0.0001 0.0001
Echinococcus granulosus protein kinase shaggy 0.0516 0.1091 0.1091
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Plasmodium falciparum DNA gyrase subunit A 0.0238 0.029 0.0828
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0563 0.1225 0.1225
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0796 0.19 0.2388
Loa Loa (eye worm) hypothetical protein 0.0143 0.0017 0.0021
Brugia malayi Tyrosine-protein kinase PR2 0.0143 0.0017 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Brugia malayi Kinase associated domain 1 family protein 0.0269 0.038 0.0477
Loa Loa (eye worm) hypothetical protein 0.0163 0.0074 0.0093
Loa Loa (eye worm) RGC/RGC protein kinase 0.0143 0.0017 0.0021
Brugia malayi Protein kinase domain containing protein 0.096 0.2372 0.2982
Echinococcus multilocularis tyrosine protein kinase csk 0.0143 0.0017 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0184 0.0133 0.0182
Loa Loa (eye worm) TK protein kinase 0.0143 0.0017 0.0021
Onchocerca volvulus 0.032 0.0527 0.1026
Giardia lamblia Kinase, CAMK CAMKL 0.029 0.0438 0.1274
Brugia malayi hypothetical protein 0.0143 0.0017 0.0021
Echinococcus granulosus mitogen activated protein kinase 14 0.0642 0.1456 0.1456
Trypanosoma cruzi rac serine-threonine kinase, putative 0.1392 0.3618 1
Schistosoma mansoni serine/threonine protein kinase 0.1018 0.2539 0.6144
Trichomonas vaginalis AGC family protein kinase 0.0866 0.2101 0.3416
Trypanosoma cruzi rac serine-threonine kinase, putative 0.129 0.3323 0.918
Echinococcus multilocularis cyclin dependent kinase 1 0.0563 0.1225 0.1682
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0563 0.1225 0.154
Brugia malayi Protein kinase domain containing protein 0.1132 0.2868 0.3605
Onchocerca volvulus 0.0588 0.1299 0.2578
Giardia lamblia Kinase, AGC PKA 0.0866 0.2101 0.6305
Loa Loa (eye worm) gastrulation defective protein 1 0.0144 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0269 0.038 0.0477
Trichomonas vaginalis conserved hypothetical protein 0.0162 0.0071 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0276 0.0631
Loa Loa (eye worm) hypothetical protein 0.0441 0.0873 0.1098
Echinococcus multilocularis SH2 motif 0.0152 0.004 0.0056
Loa Loa (eye worm) TK/Met protein kinase 0.0143 0.0017 0.0021
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2101
Onchocerca volvulus 0.0237 0.0287 0.0544
Brugia malayi Guanylyl cyclase protein 23 0.0143 0.0017 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Echinococcus granulosus casein kinase I gamma 0.0484 0.0998 0.0998
Loa Loa (eye worm) TK protein kinase 0.0758 0.1789 0.2249
Loa Loa (eye worm) hypothetical protein 0.0443 0.0882 0.1108
Leishmania major protein kinase, putative 0.0262 0.0358 0.1639
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Echinococcus multilocularis tyrosine protein kinase HCK 0.0446 0.0888 0.1219
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0636 0.1437 0.1437
Schistosoma mansoni nck2/grb4 0.0264 0.0365 0.0849
Loa Loa (eye worm) TK protein kinase 0.0143 0.0017 0.0021
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.1171 0.2981 0.2981
Schistosoma mansoni serine/threonine protein kinase 0.0563 0.1225 0.2944
Echinococcus granulosus tyrosine kinase 0.0597 0.1326 0.1326
Echinococcus granulosus cyclin dependent kinase 0.0563 0.1225 0.1225
Trichomonas vaginalis CMGC family protein kinase 0.0333 0.0564 0.0897
Trichomonas vaginalis AGC family protein kinase 0.0221 0.024 0.0366
Echinococcus multilocularis casein kinase I alpha 0.0352 0.0619 0.085
Brugia malayi Raf kinase 0.0143 0.0017 0.0021
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0281 0.0414 0.0651
Echinococcus multilocularis tyrosine protein kinase csk 0.0143 0.0017 0.0023
Trypanosoma cruzi cdc2-related kinase 3 0.0563 0.1225 0.3356
Brugia malayi hypothetical protein 0.0709 0.1648 0.2072
Schistosoma mansoni serine/threonine protein kinase 0.0563 0.1225 0.2944
Echinococcus granulosus casein kinase I delta 0.0352 0.0619 0.0619
Brugia malayi Protein kinase domain containing protein 0.0325 0.0541 0.0681
Brugia malayi Protein kinase domain containing protein 0.0587 0.1296 0.1628
Echinococcus granulosus calcium activated potassium channel 0.0388 0.0722 0.0722
Loa Loa (eye worm) hypothetical protein 0.0162 0.0071 0.0089
Entamoeba histolytica protein kinase, putative 0.022 0.0238 0.0362
Brugia malayi Immunoglobulin I-set domain containing protein 0.0175 0.0106 0.0134
Echinococcus granulosus N chimaerin 0.0315 0.0512 0.0512
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0275 0.0397 0.0499
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Giardia lamblia Kinase, NEK 0.0434 0.0854 0.2533
Echinococcus granulosus cGMP dependent protein kinase 1 0.0324 0.0538 0.0538
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2884
Leishmania major protein kinase, putative 0.0276 0.04 0.1841
Trichomonas vaginalis CMGC family protein kinase 0.0563 0.1225 0.198
Brugia malayi Protein kinase domain containing protein 0.1267 0.3257 0.4094
Trypanosoma brucei SNF1-related protein kinases, putative 0.0281 0.0413 0.0649
Echinococcus granulosus SH2 motif 0.0152 0.004 0.004
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1117 0.2824 0.3877
Brugia malayi RhoGAP domain containing protein 0.0315 0.0512 0.0643
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0234 0.0277 0.0426
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0168 0.0087 0.011
Plasmodium vivax calcium-dependent protein kinase, putative 0.0321 0.0528 0.1546
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0152 0.004 0.0051
Echinococcus multilocularis growth factor receptor bound protein 2 0.0264 0.0365 0.0501
Trypanosoma brucei protein kinase, putative 0.0262 0.0358 0.056
Entamoeba histolytica protein kinase, putative 0.022 0.0238 0.0362
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0866 0.2101 0.3416
Trypanosoma brucei DNA topoisomerase ii 0.0224 0.0249 0.0381
Schistosoma mansoni shc transforming protein 0.0152 0.004 0.0058
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Loa Loa (eye worm) TK protein kinase 0.0143 0.0017 0.0021
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0143 0.0017 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.057 0.1247 0.5904
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0221 0.024 0.062
Schistosoma mansoni tyrosine kinase 0.1285 0.3309 0.802
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0321 0.0528 0.0528
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.022 0.0238 0.0299
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus multilocularis cyclin dependent kinase 5 0.0563 0.1225 0.1682
Entamoeba histolytica protein kinase, putative 0.0234 0.0279 0.0429
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0382 0.0706 0.1914
Loa Loa (eye worm) hypothetical protein 0.0162 0.0071 0.0089
Echinococcus granulosus growth factor receptor bound protein 2 0.027 0.0382 0.0382
Brugia malayi hypothetical protein 0.0152 0.004 0.0051
Echinococcus granulosus insulin receptor 0.1285 0.3309 0.3309
Schistosoma mansoni serine/threonine protein kinase 0.1365 0.3538 0.8578
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0866 0.2101 0.2884
Brugia malayi Protein kinase domain containing protein 0.0184 0.0133 0.0167
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0681 0.1567 0.2151
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Echinococcus granulosus retinal guanylyl cyclase 2 0.0143 0.0017 0.0017
Entamoeba histolytica protein kinase, putative 0.0281 0.0412 0.0648
Echinococcus multilocularis basement membrane specific heparan sulfate 0.031 0.0498 0.0683
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Leishmania major mitochondrial DNA topoisomerase II 0.0224 0.0249 0.1114
Leishmania major protein kinase A catalytic subunit isoform 1 0.0866 0.2101 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0152 0.004 0.0056
Entamoeba histolytica protein kinase, putative 0.0145 0.002 0.0006
Giardia lamblia Kinase, CK1 Casein kinase 0.0352 0.0619 0.1822
Plasmodium falciparum serine/threonine protein kinase KIN 0.0281 0.0413 0.1198
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0281 0.0413 0.11
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0563 0.1225 0.5798
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0129 0.0162
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0143 0.0017 0.0017
Echinococcus multilocularis Immunoglobulin 0.031 0.0498 0.0683
Entamoeba histolytica serine/threonine protein kinase, putative 0.0281 0.0413 0.0649
Giardia lamblia Kinase, AGC PKA 0.129 0.3323 1
Trypanosoma brucei protein kinase, putative 0.0391 0.0731 0.117
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Brugia malayi Protein kinase domain containing protein 0.1267 0.3257 0.4094
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.016 0.0064 0.0078
Echinococcus multilocularis tyrosine protein kinase csk 0.0143 0.0017 0.0023
Echinococcus multilocularis casein kinase I gamma 0.0484 0.0998 0.137
Plasmodium falciparum calcium-dependent protein kinase 7 0.0221 0.024 0.0676
Entamoeba histolytica protein kinase, putative 0.0221 0.024 0.0366
Giardia lamblia Kinase, NEK 0.0154 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Entamoeba histolytica cell division protein kinase 2, putative 0.0571 0.125 0.2021
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0497 0.1036 0.283
Schistosoma mansoni serine/threonine protein kinase 0.0986 0.2446 0.5918
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0563 0.1225 0.154
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0152 0.004 0.004
Plasmodium vivax protein kinase, putative 0.0179 0.012 0.0312
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Entamoeba histolytica protein kinase, putative 0.0497 0.1036 0.167
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0636 0.1437 0.1972
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Echinococcus granulosus NCK adaptor protein 0.0264 0.0365 0.0365
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0206 0.0197 0.0271
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0154 0.0048 0.0088
Schistosoma mansoni unc-13 (munc13) 0.0175 0.0106 0.0218
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0281 0.0413 0.0519
Schistosoma mansoni adapter molecule crk 0.0264 0.0365 0.0849
Onchocerca volvulus 0.0234 0.0277 0.0522
Entamoeba histolytica protein kinase, putative 0.0234 0.0279 0.0429
Leishmania major protein kinase A catalytic subunit 0.0866 0.2101 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.071 0.1651 0.1651
Brugia malayi Protein kinase domain containing protein 0.0563 0.1225 0.154
Loa Loa (eye worm) AGC/PKA protein kinase 0.0866 0.2101 0.2641
Echinococcus granulosus activated cdc42 kinase 1 0.0325 0.0541 0.0541
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0197 0.0172 0.0236
Schistosoma mansoni cell adhesion molecule 0.0175 0.0106 0.0219
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0152 0.004 0.0056
Echinococcus granulosus casein kinase i 0.0352 0.0619 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0351 0.0814
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0221 0.024 0.0366
Loa Loa (eye worm) hypothetical protein 0.0441 0.0873 0.1098
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0267 0.0372 0.0511
Entamoeba histolytica hypothetical protein 0.077 0.1823 0.296
Echinococcus granulosus protein kinase c eta type 0.0163 0.0074 0.0074
Leishmania major serine/threonine-protein kinase a, putative 0.0221 0.024 0.1072
Brugia malayi intracellular kinase 0.0516 0.1091 0.1371
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0245 0.031 0.039
Loa Loa (eye worm) hypothetical protein 0.0706 0.164 0.2061
Leishmania major protein kinase A catalytic subunit isoform 2 0.0866 0.2101 1
Echinococcus granulosus epidermal growth factor receptor 0.1567 0.4122 0.4122
Brugia malayi Variant SH3 domain containing protein 0.0263 0.0363 0.0456
Toxoplasma gondii histone kinase SNF1, putative 0.0281 0.0413 0.0682
Loa Loa (eye worm) TK/FER protein kinase 0.0295 0.0454 0.0571
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0048 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2036 0.331
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0321 0.0528 0.0724
Echinococcus multilocularis protein KINase family member (kin 25) 0.0214 0.0219 0.03
Trichomonas vaginalis CMGC family protein kinase 0.0611 0.1366 0.2212
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0262 0.0358 0.0588
Echinococcus granulosus nervana 2 0.1171 0.2981 0.2981
Brugia malayi STE20-like kinase MST 0.0803 0.1918 0.241
Echinococcus multilocularis cyclin dependent kinase 19 0.0262 0.0359 0.0493
Onchocerca volvulus 0.0234 0.0277 0.0522
Brugia malayi Protein kinase domain containing protein 0.0143 0.0017 0.0021
Echinococcus multilocularis activated cdc42 kinase 1 0.0325 0.0541 0.0743
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0264 0.0365 0.0849
Brugia malayi C1-like domain containing protein 0.0722 0.1686 0.2119
Trypanosoma cruzi polo-like protein kinase, putative 0.0844 0.2036 0.5608
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.022 0.0238 0.0326
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0222 0.0244 0.0306
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1223 0.3129 0.3129
Echinococcus granulosus cyclin dependent kinase 19 0.0262 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0866 0.2101 0.2641
Leishmania major protein kinase, putative 0.0221 0.024 0.1072
Entamoeba histolytica hypothetical protein 0.0145 0.002 0.0006
Loa Loa (eye worm) AGC/PKN protein kinase 0.1391 0.3613 0.4541
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0384 0.0711 0.0893
Trypanosoma brucei polo-like protein kinase 0.0844 0.2036 0.331
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0372 0.0583
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0554 0.12 0.1508
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0866 0.2101 0.2641
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Schistosoma mansoni hypothetical protein 0.0172 0.01 0.0202
Brugia malayi casein kinase I 0.0352 0.0619 0.0778
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0709 0.1648 0.2072
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0434 0.0855 0.1075
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0357 0.0633 0.0796
Schistosoma mansoni tyrosine kinase 0.093 0.2285 0.5527
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0259 0.0351 0.0441
Schistosoma mansoni tyrosine kinase 0.1285 0.3309 0.802
Loa Loa (eye worm) hypothetical protein 0.032 0.0527 0.0663
Schistosoma mansoni hypothetical protein 0.0163 0.0074 0.014
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0428 0.0837 0.1052
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0408 0.0779 0.1857
Echinococcus granulosus tyrosine protein kinase 0.0629 0.1417 0.1417
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0017 0.0021
Entamoeba histolytica protein kinase, putative 0.027 0.0382 0.0599
Giardia lamblia Kinase, CDC7 0.0234 0.0277 0.0786
Giardia lamblia Aurora kinase 0.0524 0.1114 0.332
Trichomonas vaginalis AGC family protein kinase 0.0524 0.1114 0.1799
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0245 0.031 0.0426
Echinococcus multilocularis nervana 2 0.1171 0.2981 0.4091
Trichomonas vaginalis AGC family protein kinase 0.0262 0.036 0.0562
Loa Loa (eye worm) TK/DDR protein kinase 0.0143 0.0017 0.0021
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0781 0.1856 0.3699
Schistosoma mansoni tensin 0.0152 0.004 0.0058
Onchocerca volvulus Tyrosine kinase homolog 0.1868 0.499 1
Entamoeba histolytica protein kinase, putative 0.0446 0.0888 0.1428
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0815 0.1954 0.2456
Onchocerca volvulus 0.0893 0.2178 0.4346
Loa Loa (eye worm) hypothetical protein 0.037 0.067 0.0842
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.022 0.0238 0.106
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0382 0.0706 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0262 0.0358 0.056
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.032 0.0527 0.1418
Echinococcus multilocularis myotubularin protein 13 0.0266 0.0369 0.0507
Schistosoma mansoni diacylglycerol kinase theta 0.0163 0.0074 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0277 0.0633
Schistosoma mansoni tyrosine kinase 0.071 0.1651 0.3981
Trypanosoma cruzi NIMA-related kinase, putative 0.0221 0.024 0.062
Trichomonas vaginalis AGC family protein kinase 0.1027 0.2565 0.4176
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0434 0.0855 0.2328
Echinococcus multilocularis dual specificity protein kinase clk2 0.0434 0.0855 0.1174
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0051
Toxoplasma gondii NEK kinase 0.0154 0.0048 0.0055
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1365 0.3538 0.4856
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0163 0.0074 0.0093
Entamoeba histolytica PH domain containing protein kinase, putative 0.0969 0.2396 0.39
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0413 0.0965
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0276 0.04 0.1065
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0173 0.0101 0.0138
Schistosoma mansoni tensin-related 0.0152 0.004 0.0058
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0154 0.0048 0.0088
Trypanosoma cruzi polo-like protein kinase, putative 0.0844 0.2036 0.5608
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.0413 0.0649
Echinococcus granulosus suppressor of cytokine signaling 7 0.0152 0.004 0.004
Schistosoma mansoni tensin-related 0.0152 0.004 0.0058
Echinococcus granulosus tyrosine protein kinase Src42A 0.046 0.0929 0.0929
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1335 0.3453 0.474
Loa Loa (eye worm) hypothetical protein 0.0447 0.0891 0.112
Trichomonas vaginalis AGC family protein kinase 0.226 0.6119 1
Brugia malayi diacylglycerol kinase 0.0163 0.0074 0.0093
Schistosoma mansoni protein kinase 0.0524 0.1114 0.2674
Onchocerca volvulus 0.0152 0.004 0.0048
Giardia lamblia Kinase, CMGC CDK 0.0563 0.1225 0.3656
Loa Loa (eye worm) TK/FAK protein kinase 0.1462 0.3818 0.4799
Echinococcus granulosus expressed conserved protein 0.0152 0.004 0.004
Echinococcus granulosus tyrosine protein kinase Fyn 0.071 0.1651 0.1651
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0262 0.036 0.0562
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0844 0.2036 0.969
Brugia malayi SH2 domain containing protein 0.0152 0.004 0.0051
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0221 0.024 0.062
Echinococcus multilocularis insulin receptor 0.1285 0.3309 0.4542
Schistosoma mansoni protein kinase C 0.0173 0.0101 0.0205
Entamoeba histolytica PH domain containing protein kinase, putative 0.1392 0.3618 0.5901
Echinococcus granulosus protein kinase C gamma type 0.1201 0.3067 0.3067
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1335 0.3453 0.3453
Loa Loa (eye worm) TK/FER protein kinase 0.091 0.2227 0.2798
Trichomonas vaginalis AGC family protein kinase 0.016 0.0064 0.0078
Loa Loa (eye worm) hypothetical protein 0.0444 0.0883 0.111
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0216 0.0225 0.0631
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0528 0.1245
Loa Loa (eye worm) TK/INSR protein kinase 0.1285 0.3309 0.4159
Leishmania major folate/biopterin transporter, putative 0.0221 0.024 0.1072
Trypanosoma brucei casein kinase I, isoform 2 0.0352 0.0619 0.0987
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.071 0.1651 0.2266
Brugia malayi hypothetical protein 0.0162 0.0071 0.0089
Schistosoma mansoni tyrosine kinase 0.0791 0.1884 0.4549
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.017 0.0373
Echinococcus multilocularis protein kinase c epsilon type 0.1307 0.3372 0.4629
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0367 0.066 0.083
Brugia malayi P38 map kinase family protein 2 0.0642 0.1456 0.1829
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0321 0.0528 0.0528
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0152 0.004 0.0056
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0175 0.0106 0.0146
Brugia malayi MAP kinase sur-1 0.0382 0.0706 0.0887
Schistosoma mansoni neuroglian 0.0175 0.0106 0.0219
Brugia malayi hypothetical protein 0.0348 0.0608 0.0764
Entamoeba histolytica protein kinase domain containing protein 0.0462 0.0936 0.1506
Loa Loa (eye worm) SH2 domain-containing protein 0.0152 0.004 0.0051
Loa Loa (eye worm) RGC/RGC protein kinase 0.0143 0.0017 0.0021
Trichomonas vaginalis AGC family protein kinase 0.1027 0.2565 0.4176

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) 0 uM Stimulation of dopamine-sensitive rat caudate adenylate cyclase or antagonism of dopamine stimulus as measure of D1 efficacy; No stimulation ChEMBL. 2875183
K Bind (binding) = 1.97 uM Affinity for Dopamine receptor D1 binding sites was evaluated in a test involving displacement of [3H]- fenoldopam in rat striatum ChEMBL. 2875183
K Bind (binding) = 1.97 uM Affinity for Dopamine receptor D1 binding sites was evaluated in a test involving displacement of [3H]- fenoldopam in rat striatum ChEMBL. 2875183
K Bind (binding) = 4.47 uM Affinity for Dopamine receptor D2 was evaluated from the ability of the compound to displace [3H]-spiroperidol from homogenized bovine pituitary ChEMBL. 2875183
K Bind (binding) = 4.47 uM Affinity for Dopamine receptor D2 was evaluated from the ability of the compound to displace [3H]-spiroperidol from homogenized bovine pituitary ChEMBL. 2875183

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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