Detailed information for compound 770560

Basic information

Technical information
  • TDR Targets ID: 770560
  • Name: 2-cyano-3-[2-(2,3-dimethylphenoxy)-9-methyl-4 -oxopyrido[1,2-a]pyrimidin-3-yl]-N-ethylprop- 2-enamide
  • MW: 402.446 | Formula: C23H22N4O3
  • H donors: 1 H acceptors: 3 LogP: 2.97 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNC(=O)C(=Cc1c(Oc2cccc(c2C)C)nc2n(c1=O)cccc2C)C#N
  • InChi: 1S/C23H22N4O3/c1-5-25-21(28)17(13-24)12-18-22(30-19-10-6-8-14(2)16(19)4)26-20-15(3)9-7-11-27(20)23(18)29/h6-12H,5H2,1-4H3,(H,25,28)/b17-12+
  • InChiKey: FYUHHOBJZDBLAD-SFQUDFHCSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (E)-2-cyano-3-[2-(2,3-dimethylphenoxy)-9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl]-N-ethylprop-2-enamide
  • (E)-2-cyano-3-[2-(2,3-dimethylphenoxy)-9-methyl-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-N-ethyl-prop-2-enamide
  • 2-cyano-3-[2-(2,3-dimethylphenoxy)-9-methyl-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-N-ethyl-prop-2-enamide
  • (E)-2-cyano-3-[2-(2,3-dimethylphenoxy)-9-methyl-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-N-ethylprop-2-enamide
  • 2-cyano-3-[2-(2,3-dimethylphenoxy)-9-methyl-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-N-ethylprop-2-enamide
  • 2-cyano-3-[2-(2,3-dimethylphenoxy)-4-keto-9-methyl-pyrido[1,2-a]pyrimidin-3-yl]-N-ethyl-acrylamide
  • (E)-2-cyano-3-[2-(2,3-dimethylphenoxy)-4-keto-9-methyl-pyrido[1,2-a]pyrimidin-3-yl]-N-ethyl-acrylamide
  • ZINC03644294
  • STOCK4S-60505

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni phd/f-box containing protein 0.0011 0.0029 0.0088
Onchocerca volvulus 0.0007 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0034 0.008
Brugia malayi RNA recognition motif domain containing protein 0.0022 0.0094 0.0223
Schistosoma mansoni neuropeptide receptor 0.0007 0.0006 0.0019
Echinococcus granulosus serotonin receptor 0.0007 0.0006 0.0013
Loa Loa (eye worm) thioredoxin reductase 0.0031 0.0143 0.0341
Echinococcus multilocularis transmembrane protease serine 3 0.0007 0.0001 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0009 0.0013 0.0047
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0008 0.0012 0.0029
Schistosoma mansoni aldehyde dehydrogenase 0.0008 0.0011 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0083
Echinococcus multilocularis microtubule associated protein 2 0.0242 0.1391 0.1391
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0032 0.0151 0.0987
Echinococcus multilocularis PHD finger protein rhinoceros 0.0013 0.0039 0.0039
Trypanosoma brucei trypanothione reductase 0.0031 0.0143 0.3612
Echinococcus multilocularis neuropeptide FF receptor 2 0.0007 0.0006 0.0006
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0011 0.0025 0.0059
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0015 0.0053 0.1341
Schistosoma mansoni egf-like domain protein 0.0008 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0034 0.0102
Brugia malayi Dopamine receptor 0.0007 0.0006 0.0015
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0008 0.0012 0.0026
Loa Loa (eye worm) aldehyde dehydrogenase 0.0008 0.0011 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.0503 0.2927 0.2927
Echinococcus granulosus tar DNA binding protein 0.0022 0.0094 0.0202
Mycobacterium tuberculosis Conserved protein 0.0074 0.0396 0.1448
Echinococcus granulosus dro:myosuppressin receptor 0.0007 0.0006 0.0013
Leishmania major glycerol uptake protein, putative 0.0043 0.0218 0.2552
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0034 0.0073
Echinococcus granulosus zinc finger protein 0.046 0.2674 0.5768
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0008 0.0011 0.004
Leishmania major 4-coumarate:coa ligase-like protein 0.0009 0.0013 0.0151
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0008 0.0011 0.0275
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0012 0.0035 0.0105
Schistosoma mansoni hypothetical protein 0.0102 0.0564 0.1699
Schistosoma mansoni aldehyde dehydrogenase 0.0151 0.0853 0.2568
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.1127 0.1127
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0024 0.0102 0.0243
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0008 0.0011 0.0281
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Echinococcus multilocularis carbonic anhydrase II 0.0058 0.0305 0.0305
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Brugia malayi G-protein alpha subunit 0.0008 0.0012 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0102 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0102 0.0517
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.028 1
Giardia lamblia PHD finger protein 15 0.0013 0.0039 0.2541
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0008 0.0011 0.0024
Echinococcus granulosus tumor protein p63 0.0351 0.2036 0.4392
Echinococcus multilocularis dnaJ subfamily B 0.0465 0.2706 0.2706
Echinococcus granulosus Smad4 0.0008 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0396 1
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0048
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0025 0.062
Echinococcus multilocularis mitogen activated protein kinase 3 0.0024 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0029 0.0069
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.1127 0.3393
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0015 0.0053 0.1347
Brugia malayi beta-lactamase family protein 0.0074 0.0396 0.0943
Loa Loa (eye worm) hypothetical protein 0.0019 0.0076 0.0181
Entamoeba histolytica hypothetical protein 0.0037 0.0183 0.8394
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0052 0.0269 0.0269
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0015 0.0053 0.0622
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0083
Brugia malayi MBOAT family protein 0.0043 0.0218 0.0519
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0008 0.0009 0.0021
Onchocerca volvulus Matrilysin homolog 0.0483 0.2814 1
Schistosoma mansoni hypothetical protein 0.0044 0.0224 0.0673
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0016 0.0059 0.0127
Schistosoma mansoni lipoxygenase 0.0059 0.0313 0.0941
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0034 0.0119
Loa Loa (eye worm) hypothetical protein 0.0074 0.0396 0.0943
Onchocerca volvulus 0.0007 0.0006 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0008 0.0011 0.0011
Brugia malayi ecdysteroid receptor 0.0012 0.0034 0.008
Brugia malayi mbt repeat family protein 0.0018 0.0067 0.0161
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0396 0.259
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0309 0.0931
Brugia malayi Matrixin family protein 0.0218 0.1248 0.297
Plasmodium vivax SET domain protein, putative 0.0044 0.0219 0.5538
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0008 0.0012 0.0061
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0371 0.0371
Echinococcus granulosus twitchin 0.0014 0.0044 0.0095
Brugia malayi G protein-coupled receptor 0.0007 0.0006 0.0015
Trypanosoma brucei glycerol uptake protein, putative 0.0043 0.0218 0.5503
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0057
Schistosoma mansoni neuropeptide receptor 0.0007 0.0006 0.0019
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0058 0.0305 0.7709
Onchocerca volvulus 0.0007 0.0006 0.0021
Trypanosoma cruzi glycerol uptake protein, putative 0.0043 0.0218 0.55
Brugia malayi hypothetical protein 0.0125 0.0697 0.1659
Loa Loa (eye worm) intermediate filament protein 0.001 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.0074 0.0396 0.0943
Brugia malayi MH2 domain containing protein 0.0124 0.0695 0.1654
Trypanosoma brucei RNA editing exonuclease 2 0.0006 0 0.0006
Brugia malayi Matrixin family protein 0.0218 0.1248 0.297
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0043 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0011 0.0025 0.0878
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0008 0.0012 0.0029
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0 0.0001
Schistosoma mansoni hypothetical protein 0.0115 0.064 0.1928
Loa Loa (eye worm) hypothetical protein 0.0218 0.1248 0.297
Echinococcus granulosus o acyltransferase membrane bound domain 0.0043 0.0218 0.047
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0024 0.0102 0.1192
Onchocerca volvulus 0.0052 0.0271 0.096
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0034 0.008
Loa Loa (eye worm) trypsin family protein 0.0007 0.0001 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.0007 0.0006 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0009 0.0013 0.0032
Toxoplasma gondii hypothetical protein 0.0031 0.0148 0.1732
Schistosoma mansoni rab6-interacting 0.0021 0.0087 0.0263
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0043 0.0218 0.0656
Plasmodium falciparum carbonic anhydrase 0.0031 0.0148 0.5281
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0076 0.0889
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0082 0.0195
Plasmodium falciparum glutathione reductase 0.0011 0.0025 0.0878
Trichomonas vaginalis porcupine, putative 0.0043 0.0218 0.1107
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0151 0.0853 1
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0076 0.0386
Schistosoma mansoni neutral sphingomyelinase 0.0006 0 0.0001
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni carbonic anhydrase-related 0.0031 0.0148 0.0446
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0008 0.0011 0.0281
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.0006 0.0013
Brugia malayi Thioredoxin reductase 0.0031 0.0143 0.0341
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0025 0.0626
Schistosoma mansoni cell adhesion molecule 0.0016 0.0059 0.0177
Schistosoma mansoni hypothetical protein 0.0021 0.0087 0.0263
Schistosoma mansoni aldehyde dehydrogenase 0.0008 0.0011 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0044 0.0219 0.0219
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.0288
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0007 0.0006 0.0006
Brugia malayi CXXC zinc finger family protein 0.0042 0.0211 0.0503
Schistosoma mansoni aldehyde dehydrogenase 0.0151 0.0853 0.2568
Schistosoma mansoni GTP-binding protein alpha subunit 0.0008 0.0012 0.0037
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0105 0.0226
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0032 0.0151 0.0552
Schistosoma mansoni opsin-like receptor 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0048
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0044 0.0219 0.0219
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0044 0.0224 0.0532
Brugia malayi nuclear receptor NHR-88 0.0012 0.0034 0.008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0034 0.0034
Onchocerca volvulus Matrix metalloproteinase homolog 0.0483 0.2814 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0007 0.0001 0.0003
Schistosoma mansoni amine GPCR 0.0007 0.0006 0.0019
Schistosoma mansoni hypothetical protein 0.0031 0.0148 0.0446
Echinococcus granulosus hypothetical protein 0.0007 0.0006 0.0013
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0008 0.0009 0.0027
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0025 0.0626
Treponema pallidum gamma-glutamyl phosphate reductase 0.0008 0.0011 0.05
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0151 0.0853 0.3119
Onchocerca volvulus 0.0074 0.0396 0.1407
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0008 0.0012 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0 0.0006
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0011 0.0024 0.0603
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0076 0.0889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis lamin dm0 0.001 0.002 0.002
Echinococcus multilocularis lamin 0.001 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0039 0.0969
Brugia malayi PHD-finger family protein 0.0013 0.0039 0.0092
Trichomonas vaginalis helicase, putative 0.001 0.0019 0.0093
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0183 0.0551
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus multilocularis Smad4 0.0008 0.0012 0.0012
Echinococcus multilocularis enteropeptidase 0.0007 0.0001 0.0001
Echinococcus granulosus carbonic anhydrase 0.0031 0.0148 0.0319
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0012 0.0029
Schistosoma mansoni hypothetical protein 0.0309 0.1785 0.5374
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0008 0.0011 0.0071
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0008 0.0012 0.0012
Brugia malayi jmjC domain containing protein 0.0011 0.0029 0.0069
Mycobacterium ulcerans lipase LipD 0.0074 0.0396 0.259
Echinococcus granulosus o acyltransferase membrane bound domain 0.0043 0.0218 0.047
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0008 0.0011 0.0275
Echinococcus granulosus cpg binding protein 0.0045 0.0226 0.0487
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0396 1
Loa Loa (eye worm) MBOAT family protein 0.0043 0.0218 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Echinococcus granulosus orexin receptor type 2 0.0007 0.0006 0.0013
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0034 0.0073
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0008 0.0012 0.0026
Brugia malayi MH2 domain containing protein 0.0008 0.0012 0.0029
Echinococcus granulosus neuropeptide s receptor 0.0503 0.2927 0.6314
Loa Loa (eye worm) matrixin family protein 0.0483 0.2814 0.6697
Echinococcus granulosus Immunoglobulin 0.0012 0.0035 0.0076
Loa Loa (eye worm) hypothetical protein 0.0016 0.0059 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0035 0.0175
Leishmania major aldehyde dehydrogenase, putative 0.0008 0.0011 0.0128
Echinococcus multilocularis flap endonuclease 1 0.0011 0.0024 0.0024
Brugia malayi Melatonin receptor type 1A 0.0007 0.0006 0.0015
Onchocerca volvulus 0.0007 0.0006 0.0021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0019 0.0093
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0396 0.2013
Onchocerca volvulus 0.0043 0.0218 0.0774
Schistosoma mansoni rab6-interacting 0.0021 0.0087 0.0263
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0024 0.0102 0.2568
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Mycobacterium tuberculosis Probable oxidoreductase 0.0078 0.0421 0.1539
Schistosoma mansoni blooms syndrome DNA helicase 0.0009 0.0018 0.0054
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0008 0.0012 0.0037
Echinococcus granulosus mitogen activated protein kinase 0.0024 0.0102 0.022
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0034 0.0073
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.0006 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0035 0.0175
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0008 0.0011 0.0034
Echinococcus multilocularis GPCR, family 2 0.0044 0.0224 0.0224
Trypanosoma brucei protein kinase, putative 0.0024 0.0102 0.2573
Echinococcus multilocularis Immunoglobulin 0.0012 0.0035 0.0035
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0049 0.0105
Loa Loa (eye worm) hypothetical protein 0.0118 0.0658 0.1567
Brugia malayi CCR4 0.0006 0 0.0001
Schistosoma mansoni hypothetical protein 0.0569 0.3322 1
Brugia malayi Serotonin receptor 0.0007 0.0006 0.0015
Onchocerca volvulus Neuropeptide F receptor homolog 0.0007 0.0006 0.0021
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Entamoeba histolytica acyl-coA synthetase, putative 0.0009 0.0013 0.0592
Echinococcus granulosus sex peptide receptor 0.0007 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0023 0.0117
Brugia malayi Dopamine receptor protein 1 0.0007 0.0006 0.0015
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0012 0.0035 0.0404
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0008 0.0012 0.0037
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.003 0.0348
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.028 0.7069
Brugia malayi Protein kinase domain containing protein 0.0012 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0008 0.0009 0.0021
Leishmania major glycerol uptake protein, putative 0.0043 0.0218 0.2552
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0008 0.0012 0.0029
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0025 0.0977
Schistosoma mansoni smad 0.0008 0.0012 0.0037
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0011 0.0025 1
Onchocerca volvulus 0.0007 0.0001 0.0002
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.0006 0.0013
Schistosoma mansoni phosphatidylserine receptor 0.0011 0.0029 0.0088
Plasmodium falciparum cysteine repeat modular protein 1 0.001 0.0024 0.0841
Brugia malayi hypothetical protein 0.0054 0.028 0.0667
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0008 0.0011 0.0275
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0034 0.008
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0076 0.2711
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0007 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0224 0.0532
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni intermediate filament proteins 0.001 0.002 0.0061
Loa Loa (eye worm) hypothetical protein 0.0044 0.0219 0.0522
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0008 0.0011 0.0275
Loa Loa (eye worm) TK/KIN16 protein kinase 0.007 0.0374 0.089
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0025 0.062
Brugia malayi mbt repeat family protein 0.0018 0.0067 0.0161
Echinococcus granulosus phd:f box containing protein 0.0011 0.0029 0.0063
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.002 0.0504
Echinococcus granulosus bloom syndrome protein 0.0019 0.0076 0.0164
Mycobacterium leprae Probable lipase LipE 0.0074 0.0396 0.2537
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0008 0.0012 0.0037
Toxoplasma gondii calcium binding egf domain-containing protein 0.0008 0.0009 0.0101
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0032 0.0151 0.0326
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi Pre-SET motif family protein 0.0298 0.1723 0.4102
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0008 0.0012 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0034 0.008
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0058 0.0305 0.0727
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0043 0.0218 0.55
Plasmodium falciparum thioredoxin reductase 0.0031 0.0143 0.5105
Echinococcus granulosus polycomb protein SCMH1 0.0018 0.0067 0.0146
Onchocerca volvulus 0.0052 0.0271 0.0962
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.0006 0.0013
Leishmania major glycerol uptake protein, putative 0.0043 0.0218 0.2552
Onchocerca volvulus 0.0051 0.0266 0.0943
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.0006 0.0013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0074 0.0396 0.0943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0056
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0008 0.0011 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0034 0.008
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0076 0.0164
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0015 0.0053 0.2439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0016 0.008
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0218 0.1248 0.3756
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0076 0.0164
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Schistosoma mansoni polycystin 1-related 0.0021 0.0087 0.0263
Echinococcus granulosus carbonic anhydrase 0.0031 0.0148 0.0319
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.062
Echinococcus granulosus fmrfamide receptor 0.0007 0.0006 0.0013
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0396 0.2013
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0008 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Schistosoma mansoni lamin 0.001 0.002 0.0061
Echinococcus granulosus muscleblind protein 0.0118 0.0658 0.142
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0008 0.0012 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0034 0.008
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0094 0.0282
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0008 0.0011 0.05
Schistosoma mansoni adenoreceptor 0.0007 0.0006 0.0019
Entamoeba histolytica acyl-CoA synthetase, putative 0.0009 0.0013 0.0592
Echinococcus granulosus jumonji domain containing 1A 0.0011 0.0029 0.0063
Schistosoma mansoni cpg binding protein 0.0045 0.0226 0.0679
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0011 0.0029 0.0088
Brugia malayi nuclear hormone receptor 0.0012 0.0034 0.008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.0006 0.0019
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0029 0.0069
Schistosoma mansoni neuropeptide receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis glycoprotein Antigen 5 0.0007 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0025 0.0977
Brugia malayi steroid hormone receptor 0.0012 0.0034 0.008
Mycobacterium tuberculosis Putative ferredoxin reductase 0.007 0.0375 0.137
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0087 0.0208
Mycobacterium ulcerans acyl-CoA synthetase 0.0009 0.0013 0.0084
Leishmania major glycerol uptake protein, putative 0.0043 0.0218 0.2552
Schistosoma mansoni ap endonuclease 0.0032 0.0151 0.0455
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0007 0.0006 0.0019
Leishmania major hypothetical protein, conserved 0.001 0.0024 0.0276
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0015 0.0053 0.1347
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0008 0.0011 0.0034
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0031 0.0148 0.0352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0032 0.0151 0.3811
Echinococcus granulosus jumonji domain containing protein 0.0018 0.0069 0.0148
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.0006 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0035 0.0175
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0053 0.0127
Echinococcus multilocularis smad 0.0008 0.0012 0.0012
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0024 0.0594
Echinococcus granulosus PHD finger protein rhinoceros 0.0013 0.0039 0.0083
Onchocerca volvulus 0.0007 0.0002 0.0005
Onchocerca volvulus 0.0008 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0082 0.0195
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0008 0.0011 0.0071
Leishmania major hypothetical protein, conserved 0.0011 0.0029 0.0338
Echinococcus granulosus G protein coupled receptor 139 0.0007 0.0006 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0012 0.0061
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0 0.0001
Schistosoma mansoni ap endonuclease 0.0032 0.0151 0.0455
Loa Loa (eye worm) hypothetical protein 0.0008 0.0012 0.0029
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0043 0.0218 0.7781
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0011 0.0029 0.0338
Schistosoma mansoni survival motor neuron protein 0.0102 0.0564 0.1699
Brugia malayi Matrixin family protein 0.0218 0.1248 0.297
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0011 0.0029 0.0338
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0034 0.008
Schistosoma mansoni amine GPCR 0.0007 0.0006 0.0019
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0035 0.0083
Onchocerca volvulus Tyrosine kinase homolog 0.0054 0.0283 0.1004
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0043 0.0218 0.2552
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0006 0 0.0006
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0043 0.0218 0.047
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0034 0.008
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0034 0.008
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0044 0.0224 0.0224
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0087 0.0189
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.0006 0.0013
Echinococcus multilocularis histone acetyltransferase MYST2 0.002 0.0082 0.0082
Echinococcus granulosus g protein coupled receptor 0.0007 0.0006 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0012 0.0029
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0309 0.0931
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0218 0.1107
Brugia malayi jmjC domain containing protein 0.0011 0.0029 0.0069
Brugia malayi MBOAT family protein 0.0043 0.0218 0.0519
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0044 0.0224 0.0224
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0008 0.0008 0.002
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0011 0.0025 0.0878
Schistosoma mansoni GTP-binding protein alpha subunit 0.0008 0.0012 0.0037
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0031 0.0148 0.0352
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0031 0.0148 0.0352
Brugia malayi jmjC domain containing protein 0.0045 0.0227 0.0541
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0032 0.0151 1
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0144 0.081 0.1928
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0009 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0002
Loa Loa (eye worm) mbt repeat family protein 0.0018 0.0067 0.0161
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0396 0.1448
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0012 0.0026
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0008 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0059 0.0309 0.0736
Schistosoma mansoni hypothetical protein 0.0043 0.0218 0.0656
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0007 0.0001 0.0003
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0043 0.0218 0.0218
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0008 0.0011 0.0071
Brugia malayi MBOAT family protein 0.0503 0.293 0.6975
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.007 0.0375 0.137
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0219 0.0661
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0053 0.0127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0034 0.0073
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0034 0.008
Schistosoma mansoni lamin 0.001 0.002 0.0061
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.0043 0.0043
Onchocerca volvulus 0.0044 0.0219 0.0779
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0007 0.0006 0.0021
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0008 0.0011 0.004
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0012 0.0035 0.0105
Echinococcus granulosus Tolloid protein 1 0.0008 0.0009 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.004 0.0202
Onchocerca volvulus 0.0007 0.0001 0.0002
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0008 0.0011 0.0071
Plasmodium vivax hypothetical protein, conserved 0.0007 0.0002 0.0052
Brugia malayi hypothetical protein 0.0021 0.0087 0.0208
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0396 0.259
Schistosoma mansoni cript-related 0.0006 0 0.0001
Brugia malayi TAR-binding protein 0.0022 0.0094 0.0223
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0144 0.081 0.081
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0011 0.0024 0.028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0034 0.0073
Loa Loa (eye worm) hypothetical protein 0.0096 0.0527 0.1255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Schistosoma mansoni biogenic amine receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis JmjC domain containing protein 4 0.0011 0.0029 0.0029
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0076 0.3483
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0266 0.08
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0077 0.0415 0.0896
Onchocerca volvulus 0.0018 0.0067 0.0239
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0058 0.0305 0.0919
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0011 0.0025 0.0626
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0029 0.0069
Loa Loa (eye worm) hypothetical protein 0.0008 0.0009 0.0021
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0008 0.0011 0.0275
Loa Loa (eye worm) hypothetical protein 0.0013 0.0039 0.0092
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0006 0 0.0006
Plasmodium vivax glutathione reductase, putative 0.0031 0.0143 0.3608
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0007 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.1127 0.3393
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0087 0.0208
Brugia malayi Latrophilin receptor protein 2 0.0044 0.0224 0.0532
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Loa Loa (eye worm) PHD-finger family protein 0.0013 0.0039 0.0092
Mycobacterium ulcerans glutaminase 0.0122 0.0679 0.4443
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0008 0.0011 0.0055
Echinococcus multilocularis muscleblind protein 1 0.0118 0.0658 0.0658
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0008 0.0011 0.0027
Leishmania major glycerol uptake protein, putative 0.0043 0.0218 0.2552
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0158 0.0895 0.193
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0011 0.0025 0.009
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0227 0.0685
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Onchocerca volvulus 0.0008 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0051 0.0266 0.0633
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0031 0.0148 0.0352
Trypanosoma brucei glycerol uptake protein, putative 0.0043 0.0218 0.5503
Entamoeba histolytica hypothetical protein 0.0037 0.0183 0.8394
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0008 0.0012 0.0029
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.0006 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0008 0.0012 0.0026
Echinococcus granulosus 7TM GPCR rhodopsin 0.0007 0.0006 0.0013
Leishmania major aldehyde dehydrogenase, putative 0.0008 0.0011 0.0128
Schistosoma mansoni hypothetical protein 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0265 0.1528 0.3637
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Trichomonas vaginalis glutaminase, putative 0.0122 0.0679 0.3453
Schistosoma mansoni hypothetical protein 0.0037 0.0183 0.0551
Mycobacterium tuberculosis Probable dehydrogenase 0.007 0.0375 0.137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0019 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.062
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0034 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0094 0.0282
Plasmodium vivax flap endonuclease 1, putative 0.0011 0.0024 0.0603
Schistosoma mansoni hypothetical protein 0.0569 0.3322 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0042 0.0211 0.0503
Mycobacterium ulcerans hypothetical protein 0.0007 0.0001 0.0004
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0396 0.1448
Echinococcus multilocularis carbonic anhydrase 0.0031 0.0148 0.0148
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0008 0.0011 0.0071
Echinococcus multilocularis polycomb protein SCMH1 0.0018 0.0067 0.0067
Loa Loa (eye worm) TYRA-2 protein 0.0007 0.0006 0.0015
Brugia malayi hypothetical protein 0.05 0.2915 0.6939
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0008 0.0012 0.0012
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0396 0.0943
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Onchocerca volvulus Alhambra homolog 0.0013 0.0039 0.0136
Brugia malayi Bromodomain containing protein 0.0013 0.0039 0.0092
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Brugia malayi jmjC domain containing protein 0.0011 0.0029 0.0069
Loa Loa (eye worm) hypothetical protein 0.0059 0.0309 0.0736
Brugia malayi Muscleblind-like protein 0.0118 0.0658 0.1567
Onchocerca volvulus Arrow homolog 0.0008 0.0009 0.0031
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0043 0.0218 0.0656
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0018 0.0067 0.0239
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0396 0.1448
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.0006 0.0006
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0008 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0083
Schistosoma mansoni hypothetical protein 0.0007 0.0006 0.0019
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0227 0.0491
Echinococcus multilocularis thyroid hormone receptor alpha 0.0064 0.0341 0.0341
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0034 0.0034
Trypanosoma brucei carbonic anhydrase-like protein 0.0058 0.0305 0.7711
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0006 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0218 0.0519
Echinococcus multilocularis fmrfamide receptor 0.0007 0.0006 0.0006
Leishmania major aldehyde dehydrogenase, putative 0.0008 0.0011 0.0128
Echinococcus granulosus o acyltransferase membrane bound domain 0.0043 0.0218 0.047
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0034 0.0102
Brugia malayi hypothetical protein 0.0037 0.0183 0.0436
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0091 0.05 0.1505
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0034 0.0073
Brugia malayi latrophilin 2 splice variant baaae 0.0096 0.0527 0.1255
Mycobacterium leprae PROBABLE HYDROLASE 0.0265 0.1528 1
Echinococcus multilocularis carbonic anhydrase 0.0031 0.0148 0.0148
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0218 0.1248 0.297
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0012 0.0012
Schistosoma mansoni DNA helicase recq1 0.0019 0.0076 0.0229
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0305 0.0727
Trypanosoma cruzi glycerol uptake protein, putative 0.0043 0.0218 0.55
Toxoplasma gondii aldehyde dehydrogenase 0.0151 0.0853 1
Schistosoma mansoni glutaminase 0.0122 0.0679 0.2045
Echinococcus granulosus neutral sphingomyelinase 0.0006 0 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0044 0.0219 0.257
Onchocerca volvulus 0.0007 0.0006 0.0021
Brugia malayi intermediate filament protein 0.001 0.002 0.0048
Schistosoma mansoni nephrin 0.0013 0.004 0.0121
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0008 0.0011 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0024 0.0121
Echinococcus granulosus microtubule associated protein 2 0.0242 0.1391 0.3
Brugia malayi Pre-SET motif family protein 0.0044 0.0219 0.0522
Mycobacterium ulcerans aldehyde dehydrogenase 0.0151 0.0853 0.5582
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.002 0.0234
Onchocerca volvulus 0.0007 0.0006 0.0021
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0032 0.0151 0.1768
Plasmodium vivax cysteine repeat modular protein 1, putative 0.001 0.0024 0.0595
Entamoeba histolytica hypothetical protein, conserved 0.0043 0.0218 1
Schistosoma mansoni carbon catabolite repressor protein 0.0006 0 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.1127 0.2431
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.0006 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.081 0.2439
Loa Loa (eye worm) glutaminase 0.0122 0.0679 0.1617
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0161
Echinococcus granulosus SAM and MBT domain containing protein 0.0018 0.0067 0.0146
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0007 0.0001 0.0003
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0008 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0118 0.0658 0.1567
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0017 0.0083
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0076 0.0181
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0087 0.0189
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0007 0.0006 0.0013
Loa Loa (eye worm) MBOAT family protein 0.0043 0.0218 0.0519
Loa Loa (eye worm) hypothetical protein 0.0017 0.0064 0.0153
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0197 0.1127 0.2683
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0019 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0057
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0007 0.0006 0.0006
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0007 0.0001 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0396 0.2013
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0008 0.0011 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0012 0.0033 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.062
Brugia malayi hypothetical protein 0.0012 0.0035 0.0083
Echinococcus granulosus mixed lineage leukemia protein mll 0.0012 0.0033 0.0072
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0034 0.008
Schistosoma mansoni hypothetical protein 0.0007 0.0006 0.0019
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0012 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0007 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0396 1
Mycobacterium ulcerans hypothetical protein 0.0009 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Loa Loa (eye worm) matrixin family protein 0.0527 0.3071 0.7309
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0007 0.0002 0.0053
Schistosoma mansoni hypothetical protein 0.0465 0.2706 0.8147
Echinococcus granulosus histone lysine methyltransferase setb 0.0044 0.0219 0.0473
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.0006 0.0015
Schistosoma mansoni nocturnin 0.0006 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0053 0.027
Schistosoma mansoni lipoxygenase 0.0021 0.0087 0.0263
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0018 0.0067 0.0203
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus granulosus lamin dm0 0.001 0.002 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0034 0.008
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0008 0.0011 0.004
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0012 0.0035 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0034 0.008
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0002
Echinococcus multilocularis fibrillin 1 0.0008 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0016 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Giardia lamblia Alcohol dehydrogenase 0.0008 0.0011 0.0721
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0034 0.0034
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0008 0.0011 0.0275
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0396 0.1192
Echinococcus multilocularis mitogen activated protein kinase 0.0024 0.0102 0.0102
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0032 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0024 0.0105 0.0315
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0396 1
Brugia malayi Serotonin receptor 0.0007 0.0006 0.0015
Brugia malayi Matrixin family protein 0.0218 0.1248 0.297
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0007 0.0002 0.0073
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0058 0.0176
Trypanosoma cruzi target of rapamycin kinase 3 0.0012 0.0035 0.0872
Brugia malayi Trypsin family protein 0.0007 0.0001 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0032 0.0151 0.0767
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0011 0.0025 0.0288
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0326 0.3824
Plasmodium falciparum glutathione reductase 0.0031 0.0143 0.5105
Loa Loa (eye worm) TK/ROR protein kinase 0.0012 0.0036 0.0085
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0012 0.0035 0.0877
Brugia malayi MBOAT family protein 0.0043 0.0218 0.0519
Onchocerca volvulus 0.001 0.0024 0.0084
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0009 0.0013 0.0013
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0008 0.0011 0.0275
Echinococcus multilocularis lysine specific demethylase 6a 0.0011 0.0029 0.0029
Giardia lamblia Flap structure-specific endonuclease 0.0011 0.0024 0.1582
Toxoplasma gondii hypothetical protein 0.0043 0.0218 0.2552
Entamoeba histolytica recQ family helicase, putative 0.0009 0.0018 0.0815
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni synaptojanin 0.0006 0 0.0001
Onchocerca volvulus 0.0102 0.0564 0.2005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.0006 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0326 0.0983
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0007 0.0006 0.0015
Echinococcus multilocularis RUN 0.0021 0.0087 0.0087
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0008 0.0011 0.0128
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.0006 0.0013
Echinococcus multilocularis tissue type plasminogen activator 0.001 0.0024 0.0024
Echinococcus multilocularis expressed protein 0.0008 0.0012 0.0012
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0008 0.0009 0.0021
Schistosoma mansoni jumonji domain containing protein 0.0061 0.032 0.0962
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.002 0.0082 0.0177
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0087 0.22
Schistosoma mansoni vesicular amine transporter 0.0012 0.0035 0.0105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0044 0.0224 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0083
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0032
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0011 0.0024 0.028
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0213 0.0213
Loa Loa (eye worm) hypothetical protein 0.0218 0.1248 0.297
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0396 0.0943
Trichomonas vaginalis mercuric reductase, putative 0.0011 0.0025 0.0125
Brugia malayi sulfakinin receptor protein 0.0007 0.0006 0.0015
Brugia malayi Hhat protein 0.0043 0.0218 0.0519
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0396 0.1448
Brugia malayi RE15519p 0.0007 0.0006 0.0015
Brugia malayi diacylglycerol acyltransferase 0.0043 0.0218 0.0519
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0102 0.0517
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0396 0.1448
Echinococcus multilocularis laminin 0.0008 0.0009 0.0009
Schistosoma mansoni growth hormone secretagogue receptor 0.0007 0.0006 0.0019
Echinococcus granulosus g protein coupled receptor 0.0007 0.0006 0.0013
Brugia malayi MBOAT family protein 0.0043 0.0218 0.0519
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0034 0.008
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0076 0.0181
Brugia malayi Intermediate filament tail domain containing protein 0.001 0.002 0.0048
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0007 0.0006 0.0019
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0033 0.0072
Schistosoma mansoni loxhd1 0.0021 0.0087 0.0263
Plasmodium vivax thioredoxin reductase, putative 0.0031 0.0143 0.3608
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0008 0.0011 0.0071
Onchocerca volvulus 0.0074 0.0396 0.1407
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0396 0.0854
Echinococcus multilocularis neuroglian 0.0013 0.004 0.004
Echinococcus multilocularis zinc finger protein 0.046 0.2674 0.2674
Toxoplasma gondii NADPH-glutathione reductase 0.0011 0.0025 0.0288
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0144 0.081 0.1928
Loa Loa (eye worm) hhat protein 0.0043 0.0218 0.0519
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.0043 0.0094
Echinococcus multilocularis cpg binding protein 0.0045 0.0226 0.0226
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0007 0.0006 0.0013
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0058 0.0305 0.7709
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0009 0.0013 0.0013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.1127 0.2431
Echinococcus granulosus Mastin 0.0007 0.0001 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0057
Onchocerca volvulus 0.0012 0.0034 0.0119
Trypanosoma cruzi trypanothione reductase, putative 0.0031 0.0143 0.3608
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0007 0.0006 0.0019
Brugia malayi Trypsin family protein 0.0059 0.0309 0.0736
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0007 0.0006 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0396 0.1448
Echinococcus granulosus neuropeptide receptor A26 0.0503 0.2927 0.6314
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0024 0.0102 0.2568
Loa Loa (eye worm) hypothetical protein 0.0043 0.0218 0.0519
Brugia malayi Doublecortin family protein 0.0021 0.0087 0.0208
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0008 0.0011 0.0275
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.0012 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Echinococcus multilocularis carbonic anhydrase 0.0031 0.0148 0.0148
Trichomonas vaginalis ap endonuclease, putative 0.0032 0.0151 0.0767
Schistosoma mansoni protein phosphatase 2C 0.0011 0.0029 0.0088
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus granulosus neuropeptide FF receptor 2 0.0007 0.0006 0.0013
Echinococcus multilocularis somatostatin receptor 0.0007 0.0006 0.0006
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0034 0.0102
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.028 0.7069
Echinococcus granulosus intermediate filament protein 0.001 0.002 0.0044
Schistosoma mansoni DNA helicase recq5 0.0019 0.0076 0.0229
Echinococcus multilocularis peregrin 0.0013 0.0039 0.0039
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0792 0.4636 1
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0008 0.0011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0034 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.028 0.328
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0032 0.0151 0.5391
Brugia malayi hypothetical protein 0.0021 0.0087 0.0208
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0302 0.0719
Schistosoma mansoni neuropeptide receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis Immunoglobulin 0.0012 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0008 0.0011 0.004
Loa Loa (eye worm) RNA binding protein 0.0022 0.0094 0.0223
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0087 0.0189
Schistosoma mansoni biogenic amine receptor 0.0007 0.0006 0.0019
Brugia malayi Trypsin family protein 0.0007 0.0001 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0094 0.0282
Brugia malayi MH1 domain containing protein 0.0008 0.0012 0.0029
Echinococcus granulosus neuropeptide receptor 0.0007 0.0006 0.0013
Trypanosoma cruzi GUP1, putative 0.0043 0.0218 0.55
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0006 0.0006
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0006 0.0013
Schistosoma mansoni flap endonuclease-1 0.0009 0.0018 0.0055
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.002 0.0061
Onchocerca volvulus 0.0007 0.0001 0.0002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0018 0.0208
Schistosoma mansoni aldehyde dehydrogenase 0.0008 0.0011 0.0034
Brugia malayi Protein kinase domain containing protein 0.0144 0.081 0.1928
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0013 0.0039 0.0116
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0008 0.0012 0.0037
Schistosoma mansoni cpg binding protein 0.0045 0.0226 0.0679
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0326 0.0326
Echinococcus multilocularis sterol O acyltransferase 1 0.0043 0.0218 0.0218
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0043 0.0218 0.047
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0043 0.0218 0.047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Brugia malayi putative neuropeptide receptor NPR1 0.0007 0.0006 0.0015
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0034 0.008
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0008 0.0012 0.0029
Echinococcus multilocularis serotonin receptor 0.0007 0.0006 0.0006
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0008 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0027
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0011 0.0025 0.0626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0148 0.0352
Onchocerca volvulus 0.0218 0.1248 0.4434
Schistosoma mansoni sterol O-acyltransferase 1 0.0043 0.0218 0.0656
Loa Loa (eye worm) hhat protein 0.0043 0.0218 0.0519
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0227 0.0685
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0006 0.0006
Echinococcus granulosus survival motor neuron protein 1 0.05 0.2915 0.6287
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0043 0.0218 0.047
Mycobacterium ulcerans hydrolase 0.0265 0.1528 1
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0503 0.293 0.632
Brugia malayi RNA binding protein 0.0022 0.0094 0.0223
Treponema pallidum ATP-dependent DNA helicase 0.001 0.002 0.0916
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0011 0.0025 0.0621
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0002
Echinococcus granulosus g protein coupled receptor 0.0007 0.0006 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0034 0.008
Brugia malayi hypothetical protein 0.0007 0.0001 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.028 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0019 0.0093
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0076 0.0889
Brugia malayi Trypsin-like protease protein 5 0.0007 0.0001 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0396 0.2013
Onchocerca volvulus 0.0042 0.0211 0.075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0083
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0043 0.0218 0.2552
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0144 0.081 0.1928
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.0006 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0374 0.089
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0007 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0219 0.0661
Brugia malayi neuropeptide F receptor 0.0007 0.0006 0.0015
Brugia malayi MH1 domain containing protein 0.0008 0.0012 0.0029
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.0012 0.0029
Loa Loa (eye worm) MBOAT family protein 0.0503 0.293 0.6975
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0012 0.0026
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0032 0.0151 0.3815
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0012 0.0061
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0007 0.0006 0.0015
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0043 0.0218 1
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.028 0.7069
Brugia malayi aldehyde dehydrogenase 0.0008 0.0011 0.0027
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0012 0.0061
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0031 0.0148 0.0352
Schistosoma mansoni myosin xvIII 0.0007 0.0006 0.0019
Brugia malayi MH2 domain containing protein 0.0008 0.0012 0.0029
Onchocerca volvulus 0.0009 0.0013 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.0006 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0053 0.027
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.0313 0.0313
Echinococcus granulosus flap endonuclease 1 0.0011 0.0024 0.0052
Echinococcus granulosus laminin 0.0008 0.0009 0.0019
Schistosoma mansoni opsin-like receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0069
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi Calcitonin receptor-like protein seb-1 0.014 0.0789 0.1877
Loa Loa (eye worm) latrophilin receptor protein 2 0.0044 0.0224 0.0532
Echinococcus granulosus enteropeptidase 0.0007 0.0001 0.0002
Echinococcus multilocularis musashi 0.001 0.002 0.002
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0144 0.081 0.1747
Loa Loa (eye worm) hypothetical protein 0.0008 0.0012 0.0029
Brugia malayi Dopamine receptor protein 2 0.0007 0.0006 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.014 0.0789 0.1877
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0034 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Treponema pallidum NADH oxidase 0.0011 0.0025 0.1128
Schistosoma mansoni hypothetical protein 0.0052 0.0269 0.0811
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.0012 0.0029
Echinococcus granulosus tissue type plasminogen activator 0.001 0.0024 0.0052
Schistosoma mansoni hypothetical protein 0.0044 0.0224 0.0673
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0008 0.0012 0.0026
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0007 0.0001 0.0002
Onchocerca volvulus 0.0007 0.0006 0.0021
Brugia malayi Trypsin family protein 0.0007 0.0001 0.0002
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0008 0.0012 0.0037
Loa Loa (eye worm) carbonic anhydrase 3 0.0058 0.0305 0.0727
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0008 0.0011 0.05
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0049 0.0049
Onchocerca volvulus 0.0008 0.0012 0.0042
Schistosoma mansoni cpg binding protein 0.0042 0.0211 0.0636
Brugia malayi Aldehyde dehydrogenase protein 4 0.0008 0.0011 0.0027
Brugia malayi hypothetical protein 0.0035 0.0167 0.0398
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0151 0.0853 0.184
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0076 0.0181
Mycobacterium tuberculosis Possible penicillin-binding protein 0.047 0.2734 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0043 0.0218 0.0218
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0076 0.5027
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0034 0.008
Schistosoma mansoni carbonic anhydrase-related 0.0031 0.0148 0.0446
Echinococcus granulosus JmjC domain containing protein 4 0.0011 0.0029 0.0063
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0043 0.0218 1
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.0012 0.0037
Mycobacterium tuberculosis Probable reductase 0.007 0.0375 0.137
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0043 0.0218 0.0656
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0144 0.081 0.2878
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0151 0.0853 0.0853
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0034 0.008
Entamoeba histolytica recQ family DNA helicase 0.001 0.002 0.0916
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0015 0.0053 0.0622
Toxoplasma gondii PHD-finger domain-containing protein 0.0013 0.0039 0.0449
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0011 0.0024 0.0609
Entamoeba histolytica hypothetical protein 0.0037 0.0183 0.8394
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0009 0.0013 0.0047
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0032 0.0151 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Brugia malayi Fibulin-1 precursor 0.0008 0.0009 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0015 0.0053 0.0161
Echinococcus multilocularis tar DNA binding protein 0.0022 0.0094 0.0094
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0006 0 0.0001
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0015 0.0053 0.0053
Loa Loa (eye worm) TAR-binding protein 0.0022 0.0094 0.0223
Schistosoma mansoni hypothetical protein 0.001 0.0024 0.0072
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0031 0.0143 0.0522
Schistosoma mansoni hypothetical protein 0.0013 0.0039 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.062
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus granulosus alpha 1A adrenergic receptor 0.0007 0.0006 0.0013
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0037
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0009 0.0018 0.0448
Echinococcus multilocularis Tolloid protein 1 0.0008 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0044 0.0224 0.0673
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0008 0.0011 0.0281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Schistosoma mansoni biogenic amine receptor 0.0007 0.0006 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Onchocerca volvulus 0.0309 0.1785 0.6344
Brugia malayi follicle stimulating hormone receptor 0.0718 0.4201 1
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0006 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.062
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.002 0.0504
Onchocerca volvulus 0.0125 0.0697 0.2476
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0034 0.0073
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0008 0.0012 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0034 0.0102
Trichomonas vaginalis transmembrane protein nessy, putative 0.0043 0.0218 0.1107
Schistosoma mansoni amine GPCR 0.0007 0.0006 0.0019
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0029 0.0728
Loa Loa (eye worm) hypothetical protein 0.0008 0.0012 0.0029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0078 0.0421 0.1539
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0076 0.0181
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0008 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.014 0.0789 0.1877
Echinococcus granulosus synaptojanin 1 0.0006 0 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0219 0.0661
Echinococcus granulosus defective proboscis extension response 0.0012 0.0035 0.0076
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0007 0.0006 0.0006
Echinococcus multilocularis dro:myosuppressin receptor 0.0007 0.0006 0.0006
Schistosoma mansoni microtubule-associated protein tau 0.0242 0.1391 0.4188
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0022 0.0094 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0007 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Echinococcus multilocularis thioredoxin glutathione reductase 0.0031 0.0143 0.0143
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0076 0.0076
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.007 0.0375 0.2398
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0008 0.0012 0.0037
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0008 0.0011 0.0071
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0007 0.0005 0.0133
Schistosoma mansoni Smad4 0.0008 0.0012 0.0037
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0087 0.3112
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0034 0.0119
Mycobacterium tuberculosis Conserved protein 0.0074 0.0396 0.1448
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0017 0.0083
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0008 0.0012 0.0061
Brugia malayi G-protein coupled receptor 0.0007 0.0006 0.0015
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0008 0.0011 0.05
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0371 0.08
Schistosoma mansoni neuropeptide f receptor 76f 0.0007 0.0006 0.0019
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0008 0.0011 0.0024
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0792 0.4636 0.4636
Trypanosoma cruzi GUP1, putative 0.0043 0.0218 0.55
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0078 0.0421 0.1539
Loa Loa (eye worm) MBCTL1 0.002 0.0082 0.0195
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0008 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0148 0.0352
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0094 0.0282
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0058 0.0305 0.0727
Brugia malayi jmjC domain containing protein 0.0011 0.0029 0.0069
Brugia malayi AMP-binding enzyme family protein 0.0009 0.0013 0.0032
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0007 0.0006 0.0019
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0003
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0008 0.0011 0.0281
Echinococcus granulosus transmembrane protease serine 3 0.0007 0.0001 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.007 0.0375 0.137
Loa Loa (eye worm) melatonin receptor type 1A 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0021 0.0107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0148 0.0352
Giardia lamblia Kinase, CMGC MAPK 0.0024 0.0102 0.6739
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0037
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0517 0.3015 0.9078
Schistosoma mansoni jumonji domain containing protein 0.0011 0.0029 0.0088
Toxoplasma gondii histone lysine methyltransferase SET1 0.0082 0.0444 0.5198
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0326 0.0777
Echinococcus granulosus RUN 0.0021 0.0087 0.0189
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0183 0.0395
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0326 0.1193
Loa Loa (eye worm) hypothetical protein 0.0008 0.0012 0.0029
Toxoplasma gondii thioredoxin reductase 0.0031 0.0143 0.1674
Echinococcus multilocularis geminin 0.0569 0.3322 0.3322
Echinococcus granulosus g-protein coupled receptor 0.0007 0.0006 0.0013
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0503 0.293 0.293
Brugia malayi hypothetical protein 0.0007 0.0006 0.0015
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0024 0.0102 0.2573
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0298 0.1723 0.4102
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0008 0.0011 0.05
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.0313 0.0675
Plasmodium vivax JmjC domain containing protein 0.0011 0.0029 0.0728
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0087 0.0087
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0015 0.0053 0.2439
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0012 0.0037
Toxoplasma gondii calcium binding egf domain-containing protein 0.0008 0.0009 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.003 0.0151
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0007 0.0006 0.0013
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0044 0.0224 0.0482
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0007 0.0001 0.0003
Brugia malayi ORL1-like opioid receptor 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0064 0.0153
Trichomonas vaginalis set domain proteins, putative 0.034 0.1966 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0024 0.0102 0.2568
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0043 0.0218 0.0656
Onchocerca volvulus 0.0021 0.0087 0.0309
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Leishmania major hypothetical protein, conserved 0.0043 0.0218 0.2552
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0057
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0087 0.0087
Echinococcus granulosus expressed protein 0.0008 0.0012 0.0026
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0008 0.0009 0.0021
Schistosoma mansoni myelin transcription factor 1 myt1 0.002 0.0082 0.0247
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0096 0.0527 0.1587
Giardia lamblia NADH oxidase lateral transfer candidate 0.0011 0.0025 0.1628
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0024 0.0102 0.1192
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0034 0.0102
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.002 0.0082 0.0082
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.0006 0.0019
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0029 0.0728
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0002
Schistosoma mansoni coup transcription factor 0.0012 0.0034 0.0102
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0025 0.062
Brugia malayi GnHR receptor homolog 0.0007 0.0006 0.0015
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0043 0.0218 0.0218
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0034 0.0034
Brugia malayi putative neuropeptide receptor 0.0007 0.0006 0.0015
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0008 0.0011 0.0071
Echinococcus granulosus histone acetyltransferase MYST2 0.002 0.0082 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Echinococcus granulosus smad 0.0008 0.0012 0.0026
Brugia malayi G-protein coupled receptor 0.0007 0.0006 0.0015
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0007 0.0006 0.0019
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0008 0.0011 0.0275
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0015 0.0053 0.1341
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0011 0.0025 0.0161
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.002 0.0504
Echinococcus multilocularis jumonji domain containing protein 0.0018 0.0069 0.0069
Mycobacterium ulcerans acyl-CoA synthetase 0.0009 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0015 0.0053 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0076 0.0386
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0396 0.2537
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus granulosus mitogen activated protein kinase 3 0.0024 0.0102 0.022
Trichomonas vaginalis esterase, putative 0.0074 0.0396 0.2013
Onchocerca volvulus 0.0007 0.0006 0.0021
Echinococcus granulosus carbonic anhydrase II 0.0058 0.0305 0.0659
Brugia malayi Kringle domain containing protein 0.001 0.0024 0.0057
Schistosoma mansoni carbonic anhydrase-related 0.0031 0.0148 0.0446
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0008 0.0011 0.0275
Loa Loa (eye worm) hypothetical protein 0.0265 0.1528 0.3637
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0043 0.0218 0.0519
Onchocerca volvulus 0.0059 0.0309 0.1098
Brugia malayi larval opioid receptor 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.001 0.002 0.0048
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0326 0.0704
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0008 0.0011 0.0128
Echinococcus granulosus GPCR family 2 0.0044 0.0224 0.0482
Echinococcus multilocularis jumonji domain containing 1A 0.0011 0.0029 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0019 0.0093
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0008 0.0011 0.0027
Brugia malayi PHD-finger family protein 0.0007 0.0001 0.0003
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0034 0.0102
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.0288
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0087 0.0087
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0007 0.0006 0.0015
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0076 0.1916
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0034 0.0073
Schistosoma mansoni synaptojanin 0.0006 0 0.0001
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0006 0 0.0006
Echinococcus granulosus traf and tnf receptor associated protein 0.0006 0 0.0001
Plasmodium falciparum flap endonuclease 1 0.0011 0.0024 0.0853
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0197 0.1127 0.2683
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0009 0.0013 0.0151
Onchocerca volvulus 0.0074 0.0396 0.1407
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Onchocerca volvulus 0.0007 0.0001 0.0002
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0008 0.0011 0.004
Brugia malayi G protein-coupled receptor F59B2.13 0.0007 0.0006 0.0015
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0043 0.0218 0.0519
Schistosoma mansoni hypothetical protein 0.0044 0.0224 0.0673
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0034 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0009 0.0013 0.0084
Echinococcus multilocularis sex peptide receptor 0.0007 0.0006 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0009 0.0013 0.0592
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0008 0.0011 0.004
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.012 0.0286
Treponema pallidum alginate O-acetylation protein (algI) 0.0043 0.0218 1
Schistosoma mansoni sex comb on midleg homolog 0.0018 0.0067 0.0203
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0006 0 0.0006
Loa Loa (eye worm) G protein alpha subunit 3 0.0008 0.0012 0.0029
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0034 0.0034
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.002 0.0082 0.0195
Toxoplasma gondii ABC1 family protein 0.0074 0.0396 0.464
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus multilocularis allatostatin A receptor 0.0007 0.0006 0.0006
Echinococcus multilocularis G protein coupled receptor 139 0.0007 0.0006 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0078 0.0421 0.2701
Brugia malayi MAP kinase sur-1 0.0024 0.0102 0.0243
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Echinococcus granulosus 7tm_1 domain containing protein 0.0007 0.0006 0.0013
Onchocerca volvulus 0.0007 0.0006 0.0021
Onchocerca volvulus 0.034 0.1966 0.6987
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0077 0.0415 0.0415
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0695 0.1654
Leishmania major 4-coumarate:coa ligase-like protein 0.0009 0.0013 0.0151
Brugia malayi Smad1 0.0008 0.0012 0.0029
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0008 0.0011 0.0275
Echinococcus multilocularis neuropeptide receptor 0.0007 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0102 0.0307
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0034 0.0119
Schistosoma mansoni carbonic anhydrase 0.0031 0.0148 0.0446
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0011 0.0025 0.0161
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0043 0.0218 1
Brugia malayi beta-lactamase family protein 0.0074 0.0396 0.0943
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0008 0.0011 0.0071
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0007 0.0006 0.0006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0024 0.0102 0.2568
Onchocerca volvulus 0.001 0.002 0.0071
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0009 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0125 0.0697 0.1659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0056
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0058 0.0305 0.0919
Schistosoma mansoni aldehyde dehydrogenase 0.0008 0.0011 0.0034
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.0006 0.0019
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0718 0.4201 1
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0008 0.0009 0.0021
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0008 0.0011 0.0128
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0008 0.0012 0.0012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Leishmania major pantothenate kinase subunit, putative 0.0007 0.0002 0.0024
Loa Loa (eye worm) histone methyltransferase 0.0015 0.0049 0.0116
Echinococcus granulosus neuropeptide receptor 0.0007 0.0006 0.0013
Brugia malayi exodeoxyribonuclease III family protein 0.0032 0.0151 0.036
Echinococcus granulosus geminin 0.0569 0.3322 0.7164
Entamoeba histolytica vacuolar protein sorting 26 0.0043 0.0218 1
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0006 0 0.0001
Brugia malayi Matrixin family protein 0.0527 0.3071 0.7309
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus multilocularis roundabout 2 0.0017 0.0064 0.0064
Mycobacterium ulcerans aldehyde dehydrogenase 0.0151 0.0853 0.5582
Brugia malayi glutaminase DH11.1 0.0122 0.0679 0.1617
Echinococcus multilocularis Mastin 0.0007 0.0001 0.0001
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0043 0.0218 0.0656
Loa Loa (eye worm) hypothetical protein 0.0029 0.0136 0.0323
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0006 0 0.0006
Entamoeba histolytica G protein alpha subunit, putative 0.0008 0.0012 0.0547
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0094 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0057
Echinococcus multilocularis G-protein coupled receptor, putative 0.0007 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0218 0.1107
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0011 0.0025 0.0288
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0032 0.0151 0.6929
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0007 0.0006 0.0015
Brugia malayi glutathione reductase 0.0031 0.0143 0.0341
Mycobacterium ulcerans aldehyde dehydrogenase 0.0151 0.0853 0.5582
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0032 0.0151 0.036
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0006 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0034 0.0102
Echinococcus granulosus allatostatin A receptor 0.0007 0.0006 0.0013
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0034 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Brugia malayi Calcium binding EGF domain containing protein 0.0008 0.0009 0.0021
Loa Loa (eye worm) pigment dispersing factor receptor c 0.014 0.0789 0.1877
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0396 0.0943
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0034 0.008
Schistosoma mansoni thyroid hormone receptor 0.0064 0.0341 0.1026
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0027
Loa Loa (eye worm) Smad1 0.0008 0.0012 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0009 0.0013 0.0032
Loa Loa (eye worm) flap endonuclease-1 0.0011 0.0024 0.0058
Giardia lamblia GTOR 0.0015 0.0053 0.352
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0031 0.0148 0.0352
Echinococcus multilocularis serotonin receptor 0.0007 0.0006 0.0006
Onchocerca volvulus 0.0007 0.0006 0.0021
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0008 0.0009 0.0021
Schistosoma mansoni alpha-1 adrenergic receptor 0.0007 0.0006 0.0019
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0008 0.0011 0.0071
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0007 0.0006 0.0015
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.0006 0.0006
Echinococcus granulosus lysine specific demethylase 6a 0.0011 0.0029 0.0063
Schistosoma mansoni hypothetical protein 0.0007 0.0006 0.0019
Onchocerca volvulus 0.001 0.002 0.0071
Schistosoma mansoni histamine h1 receptor 0.0007 0.0006 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0006 0 0.0001
Echinococcus multilocularis phd:f box containing protein 0.0011 0.0029 0.0029
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0009 0.0013 0.0084
Schistosoma mansoni sex comb on midleg homolog 0.0018 0.0067 0.0203
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0076 0.0076
Echinococcus granulosus lamin 0.001 0.002 0.0044
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0032 0.0151 0.3811
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0034 0.0102
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0396 0.1192
Loa Loa (eye worm) hypothetical protein 0.0043 0.0218 0.0519
Trypanosoma cruzi glycerol uptake protein, putative 0.0043 0.0218 0.55
Brugia malayi AKH receptor 0.0007 0.0006 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.0006 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0218 0.1107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.1127 0.3393
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0008 0.0011 0.0011
Brugia malayi Hemopexin family protein 0.0309 0.1785 0.4249
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0043 0.0218 0.0218
Echinococcus granulosus somatostatin receptor 0.0007 0.0006 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0034 0.008
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0006 0.0013
Echinococcus granulosus glycoprotein Antigen 5 0.0007 0.0001 0.0002
Leishmania major carbonic anhydrase-like protein 0.0058 0.0305 0.3577
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0035 0.0175
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0008 0.0011 0.0024
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0695 0.1654
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0105 0.0105
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0019 0.0093
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0008 0.0011 0.0039
Echinococcus multilocularis neuropeptide receptor A26 0.0503 0.2927 0.2927
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0219 0.0661
Toxoplasma gondii exonuclease III APE 0.0032 0.0151 0.1768
Loa Loa (eye worm) beta-lactamase 0.0074 0.0396 0.0943
Echinococcus granulosus tachykinin peptides receptor 99D 0.0007 0.0006 0.0013
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0076 0.2711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0053 0.027
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0564 0.1344
Entamoeba histolytica hypothetical protein 0.0043 0.0218 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0034 0.0102
Brugia malayi Fibronectin type III domain containing protein 0.0012 0.0035 0.0083
Schistosoma mansoni hypothetical protein 0.0008 0.0011 0.0034
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.0006 0.0013
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0008 0.0008 0.002
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0008 0.0011 0.0027
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0007 0.0006 0.0015
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0043 0.0218 0.0656
Echinococcus granulosus peptide allatostatin:somatostatin 0.0007 0.0006 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0008 0.0011 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0183 0.0183
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0227 0.0541
Treponema pallidum exodeoxyribonuclease (exoA) 0.0032 0.0151 0.6929
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0041 0.0205 0.0442
Echinococcus granulosus roundabout 2 0.0017 0.0064 0.0138
Onchocerca volvulus 0.0021 0.0087 0.0309
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0008 0.0012 0.0012
Toxoplasma gondii PHD-finger domain-containing protein 0.0013 0.0039 0.0449
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0019 0.0093
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0008 0.0011 0.0281
Echinococcus multilocularis survival motor neuron protein 1 0.05 0.2915 0.2915
Schistosoma mansoni thyroid hormone receptor 0.0064 0.0341 0.1026
Echinococcus multilocularis muscleblind protein 0.0118 0.0658 0.0658
Mycobacterium tuberculosis Conserved protein 0.0074 0.0396 0.1448
Schistosoma mansoni zinc finger protein 0.0503 0.293 0.8821
Echinococcus granulosus thioredoxin glutathione reductase 0.0031 0.0143 0.0309
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0011 0.0025 0.0161
Echinococcus granulosus dnaJ subfamily B 0.0465 0.2706 0.5837
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.1127 0.1127
Leishmania major hypothetical protein, conserved 0.0054 0.028 0.328
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus granulosus carbonic anhydrase 0.0031 0.0148 0.0319
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0326 0.2135
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0008 0.0012 0.0061
Loa Loa (eye worm) glutaminase 2 0.0122 0.0679 0.1617
Echinococcus multilocularis neuropeptide receptor 0.0007 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0006 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0076 0.0076
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0043 0.0218 0.0218
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0008 0.0009 0.0021
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0009 0.0013 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0025 0.062
Echinococcus multilocularis tumor protein p63 0.0351 0.2036 0.2036
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0396 0.2013
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0024 0.0102 0.1192
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0007 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0034 0.008
Toxoplasma gondii kringle domain-containing protein 0.001 0.0024 0.0276
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0008 0.0011 0.0275
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0069
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.007 0.0375 0.137
Plasmodium falciparum phd finger protein, putative 0.0013 0.0039 0.137
Mycobacterium ulcerans hypothetical protein 0.0074 0.0396 0.259
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0011 0.0029 0.0734
Echinococcus multilocularis fmrfamide receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0008 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.0012 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0019 0.0093
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0006 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0396 0.0943
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0396 0.1448
Brugia malayi neuropeptide F receptor 0.0007 0.0006 0.0015
Leishmania major hypothetical protein, conserved 0.0074 0.0396 0.464
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Onchocerca volvulus Matrilysin homolog 0.0218 0.1248 0.4434
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0074 0.0396 0.0943
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0087 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0006 0.0013
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0008 0.0011 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0011 0.0056
Plasmodium falciparum thioredoxin reductase 0.0011 0.0025 0.0878
Schistosoma mansoni amine GPCR 0.0007 0.0006 0.0019
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0006 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0034 0.008
Echinococcus granulosus neuroglian 0.0013 0.004 0.0087
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0076 0.0386
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0008 0.0011 0.0071
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0008 0.0011 0.004
Plasmodium falciparum JmjC domain-containing protein, putative 0.0011 0.0029 0.103
Schistosoma mansoni cercarial elastase (S01 family) 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Loa Loa (eye worm) RecQ helicase 0.0019 0.0076 0.0181
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0043 0.0218 0.0218
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0265 0.1528 0.5588
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0073 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0017 0.0083
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0008 0.0012 0.0037
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0011 0.0025 0.0025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0007 0.0006 0.0019
Mycobacterium ulcerans beta-lactamase 0.0074 0.0396 0.259
Brugia malayi jmjC domain containing protein 0.0069 0.0371 0.0883
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0008 0.0012 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0102 0.0517
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0019 0.0093
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0326 0.2135
Entamoeba histolytica hypothetical protein 0.0037 0.0183 0.8394
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0008 0.0012 0.0012
Brugia malayi Flap endonuclease-1 0.0011 0.0024 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0034 0.0034
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0008 0.0011 0.0011
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0008 0.0012 0.0029
Brugia malayi hypothetical protein 0.0008 0.0012 0.0029
Echinococcus multilocularis g-protein coupled receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0008 0.0011 0.0071
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0007 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0011 0.0025 0.0075
Brugia malayi beta-lactamase 0.0074 0.0396 0.0943
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Loa Loa (eye worm) matrix metalloproteinase 0.0218 0.1248 0.297
Leishmania major trypanothione reductase 0.0031 0.0143 0.1674
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0034 0.0073
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.028 0.7071
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.0012 0.0029
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0052 0.0269 0.0581
Loa Loa (eye worm) hypothetical protein 0.0043 0.0218 0.0519
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0046
Echinococcus granulosus peregrin 0.0013 0.0039 0.0083
Loa Loa (eye worm) hypothetical protein 0.0054 0.028 0.0667
Loa Loa (eye worm) glutathione reductase 0.0031 0.0143 0.0341
Mycobacterium tuberculosis Probable exported protein 0.0006 0 0.0000030907
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0011 0.0025 0.0621
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0008 0.0011 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0015
Onchocerca volvulus 0.0007 0.0006 0.0021
Echinococcus granulosus sterol O acyltransferase 1 0.0043 0.0218 0.047
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.05 0.2915 0.6939
Brugia malayi Tachykinin-like peptides receptor 99D 0.0007 0.0006 0.0015
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0076 0.1921
Trichomonas vaginalis glutathione reductase, putative 0.0011 0.0025 0.0125
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0011 0.0025 0.0054
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0032 0.0151 0.3811
Schistosoma mansoni opsin-like receptor 0.0007 0.0006 0.0019
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0011 0.0025 0.0288
Echinococcus multilocularis SAM and MBT domain containing protein 0.0018 0.0067 0.0067
Entamoeba histolytica Flap nuclease, putative 0.0011 0.0024 0.1096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0035 0.0175
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0012 0.0012

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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