Detailed information for compound 899490

Basic information

Technical information
  • TDR Targets ID: 899490
  • Name: (6Z)-6-[(4-ethoxyphenyl)methylidene]-3-(3,4,5 -trimethoxyphenyl)-[1,3]thiazolo[3,2-d][1,2,4 ]triazol-5-one
  • MW: 443.516 | Formula: C22H25N3O5S
  • H donors: 0 H acceptors: 3 LogP: 4 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)C=C1SC2N(C1=O)C(NN2)c1cc(OC)c(c(c1)OC)OC
  • InChi: 1S/C22H21N3O5S/c1-5-30-15-8-6-13(7-9-15)10-18-21(26)25-20(23-24-22(25)31-18)14-11-16(27-2)19(29-4)17(12-14)28-3/h6-12H,5H2,1-4H3/b18-10-
  • InChiKey: GYNDXGPXMPRYST-ZDLGFXPLSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-[(4-ethoxyphenyl)methylidene]-3-(3,4,5-trimethoxyphenyl)-[1,3]thiazolo[3,2-d][1,2,4]triazol-5-one
  • 6-[(4-ethoxyphenyl)methylene]-3-(3,4,5-trimethoxyphenyl)thiazolo[3,2-d][1,2,4]triazol-5-one
  • (6Z)-6-[(4-ethoxyphenyl)methylene]-3-(3,4,5-trimethoxyphenyl)thiazolo[3,2-d][1,2,4]triazol-5-one
  • (6Z)-6-[(4-ethoxyphenyl)methylene]-3-(3,4,5-trimethoxyphenyl)-5-thiazolo[3,2-d][1,2,4]triazolone
  • 6-[(4-ethoxyphenyl)methylene]-3-(3,4,5-trimethoxyphenyl)-5-thiazolo[3,2-d][1,2,4]triazolone
  • (6Z)-6-(4-ethoxybenzylidene)-3-(3,4,5-trimethoxyphenyl)thiazolo[3,2-d][1,2,4]triazol-5-one
  • 6-(4-ethoxybenzylidene)-3-(3,4,5-trimethoxyphenyl)thiazolo[3,2-d][1,2,4]triazol-5-one
  • STK221389

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Alhambra homolog 0.0082 0.023 0.0542
Plasmodium vivax serine-repeat antigen (SERA) 0.0094 0.0271 0.2383
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0054 0.007
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0594 0.2083 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0025 0.0024 0.0135
Entamoeba histolytica cysteine proteinase, putative 0.0323 0.1102 0.2542
Schistosoma mansoni pyruvate kinase 0.0024 0.0018 0.0018
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0021
Brugia malayi nuclear hormone receptor 0.01 0.0295 0.0531
Schistosoma mansoni nuclear receptor nhr-48 0.01 0.0295 0.0418
Loa Loa (eye worm) PHD-finger family protein 0.0082 0.023 0.043
Toxoplasma gondii NADPH-glutathione reductase 0.0025 0.0024 0.0078
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0212 0.0701 0.07
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.009
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0028 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0483 0.1678 0.3272
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.013 0.0179
Echinococcus multilocularis Smad4 0.0059 0.0147 0.0147
Echinococcus multilocularis mothers against decapentaplegic 5 0.0059 0.0147 0.0147
Brugia malayi cathepsin B-like cysteine proteinase 0.1436 0.5129 0.9245
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0109 0.0328 0.0756
Entamoeba histolytica cysteine proteinase 2 0.0187 0.0608 0.1401
Schistosoma mansoni zinc finger protein 0.01 0.0295 0.0418
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0215 0.0711 0.3382
Toxoplasma gondii cathepsin CPL 0.0323 0.1102 0.6192
Schistosoma mansoni hypothetical protein 0.0082 0.023 0.0324
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0024 0.0018 0.0018
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0025 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.1436 0.5129 1
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0046 0.01 0.0229
Brugia malayi Cathepsin L-like precursor 0.023 0.0765 0.1379
Echinococcus granulosus Chromobox protein 3 0.0027 0.003 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0199 0.0359
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0021 0.001 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0497 0.1732 0.2499
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.003 0.0067
Echinococcus multilocularis peregrin 0.0084 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0015 0.0013
Giardia lamblia Cysteine protease 0.0094 0.0271 0.0585
Onchocerca volvulus 0.0285 0.0964 0.235
Leishmania major cathepsin L-like protease 0.0483 0.1678 0.9465
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0094 0.0271 0.2383
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0654 0.3106
Schistosoma mansoni hypothetical protein 0.0622 0.2184 0.3155
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.005 0.0063
Schistosoma mansoni intermediate filament proteins 0.0049 0.0111 0.0152
Echinococcus multilocularis jumonji domain containing protein 0.0114 0.0346 0.0346
Echinococcus granulosus inositol monophosphatase 1 0.0028 0.0033 0.0038
Echinococcus granulosus polycomb protein SCMH1 0.0034 0.0057 0.0073
Echinococcus multilocularis dnaJ subfamily B 0.0626 0.2197 0.2197
Echinococcus granulosus chromobox protein 2 0.0027 0.003 0.0034
Echinococcus multilocularis chromobox protein 2 0.0027 0.003 0.0029
Brugia malayi glutathione reductase 0.0073 0.0198 0.0357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1436 0.5129 0.7419
Toxoplasma gondii isocitrate dehydrogenase 0.0025 0.0023 0.007
Echinococcus multilocularis GPCR, family 2 0.0288 0.0975 0.0974
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.008 0.0183
Loa Loa (eye worm) hypothetical protein 0.0243 0.0811 0.1566
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.0049 0.0061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.0199 0.0909
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0011 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0271 0.0623
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.001 0.0005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0034 0.0054 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Loa Loa (eye worm) hypothetical protein 0.0093 0.0269 0.0507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0608 0.1401
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0266 0.0612
Schistosoma mansoni bromodomain containing protein 0.0057 0.0139 0.0192
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0497 0.1732 0.2499
Brugia malayi MH1 domain containing protein 0.0059 0.0147 0.0265
Brugia malayi Valyl-tRNA synthetase 0.0027 0.003 0.0054
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0039 0.0074 0.0074
Brugia malayi conserved hypotetical protein 0.01 0.0295 0.0531
Loa Loa (eye worm) hypothetical protein 0.0074 0.0199 0.037
Echinococcus granulosus mothers against decapentaplegic 5 0.0059 0.0147 0.0204
Echinococcus granulosus expressed protein 0.0075 0.0203 0.0286
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0028 0.0036
Echinococcus granulosus cathepsin b 0.1436 0.5129 0.7419
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Leishmania major cathepsin L-like protease 0.0323 0.1102 0.6213
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0028 0.0032
Plasmodium falciparum importin beta, putative 0.0023 0.0017 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0212 0.0701 0.1263
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.014 0.044 0.044
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0328 0.0756
Echinococcus multilocularis tumor protein p63 0.0476 0.1655 0.1655
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0092
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0011 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0112 0.0338 0.061
Schistosoma mansoni Smad4 0.0027 0.0028 0.0032
Mycobacterium leprae Probable pyruvate kinase PykA 0.0024 0.0018 0.0038
Schistosoma mansoni inositol monophosphatase 0.0028 0.0033 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0002
Brugia malayi cathepsin Z-like cysteine proteinase 0.0094 0.0271 0.0488
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0033 0.0133
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0094 0.0271 0.0623
Schistosoma mansoni cathepsin C 0.0094 0.0271 0.0383
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0028 0.0033 0.0074
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0025 0.0024 0.0026
Brugia malayi Thioredoxin reductase 0.0073 0.0198 0.0357
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0034 0.0057 0.0116
Brugia malayi RNA, U transporter 1 0.0066 0.0172 0.0309
Giardia lamblia Kinase, PLK 0.0127 0.0391 0.0864
Brugia malayi intermediate filament protein 0.0049 0.0111 0.02
Trypanosoma brucei DNA polymerase eta, putative 0.0076 0.0208 0.1131
Leishmania major cathepsin L-like protease 0.0323 0.1102 0.6213
Brugia malayi PHD-finger family protein 0.0032 0.005 0.009
Trypanosoma brucei glycosyl hydrolase-like protein 0.0041 0.008 0.0401
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0212 0.0701 0.1006
Loa Loa (eye worm) hypothetical protein 0.0099 0.0292 0.0552
Plasmodium falciparum LCCL domain-containing protein 0.0028 0.0035 0.0225
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0036
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0212 0.0701 0.1006
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.001 0.0009
Echinococcus granulosus thioredoxin glutathione reductase 0.0074 0.02 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Loa Loa (eye worm) isocitrate dehydrogenase 0.0025 0.0023 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.003 0.0067
Brugia malayi nuclear receptor RXR 0.0112 0.0338 0.061
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0034 0.0054 0.0211
Echinococcus granulosus cathepsin l1 0.0323 0.1102 0.1587
Onchocerca volvulus Cathepsin L homolog 0.0323 0.1102 0.2691
Mycobacterium ulcerans esterase/lipase LipP 0.0034 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0087
Loa Loa (eye worm) hypothetical protein 0.0144 0.0453 0.0866
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Schistosoma mansoni nuclear hormone receptor 0.01 0.0295 0.0418
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0019
Plasmodium vivax basic transcription factor 3b, putative 0.005 0.0115 0.0953
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0021 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0111 0.0198
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0025 0.0023 0.0112
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0034 0.0054 0.0098
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0024 0.0018 0.0038
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0024 0.0019 0.0018
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0034 0.0057 0.0073
Onchocerca volvulus 0.023 0.0765 0.1861
Trypanosoma cruzi cysteine protease, putative 0.0187 0.0608 0.1184
Brugia malayi cytoplasmic intermediate filament protein 0.0026 0.0028 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0497 0.1732 0.1732
Echinococcus multilocularis chromobox protein 1 0.0164 0.0527 0.0527
Echinococcus multilocularis lysine specific demethylase 5A 0.0099 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Echinococcus granulosus neuropeptide s receptor 0.0382 0.1314 0.1895
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0021 0.001 0.0021
Onchocerca volvulus Pyruvate kinase homolog 0.0024 0.0018 0.0022
Brugia malayi Protein cec-1. 0.0027 0.003 0.0054
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0025 0.0023 0.0059
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0497 0.1732 0.2499
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0094 0.0271 0.051
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0033 0.0074
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0028 0.0032
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0093 0.0269 0.0486
Onchocerca volvulus 0.0022 0.0011 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Loa Loa (eye worm) hypothetical protein 0.091 0.3226 0.6284
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0027 0.003 0.0175
Leishmania major DNA polymerase eta, putative 0.0076 0.0208 0.1173
Onchocerca volvulus 0.0022 0.0011 0.0002
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0018 0.0017
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0027 0.003 0.0034
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0123 0.0379 0.0539
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0085 0.0357
Brugia malayi cathepsin L precursor 0.0094 0.0271 0.0488
Brugia malayi glutaminase DH11.1 0.0187 0.0611 0.1101
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0025 0.0024 0.0135
Schistosoma mansoni cpg binding protein 0.007 0.0187 0.0262
Trichomonas vaginalis chromobox protein, putative 0.0027 0.003 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Mycobacterium ulcerans arylsulfatase AtsB 0.0046 0.01 0.0431
Trypanosoma brucei PAB1-binding protein , putative 0.0092 0.0263 0.1443
Schistosoma mansoni jumonji/arid domain-containing protein 0.0105 0.0313 0.0444
Brugia malayi latrophilin 2 splice variant baaae 0.0622 0.2184 0.3937
Plasmodium falciparum serine repeat antigen 5 0.0094 0.0271 0.2383
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.051
Trypanosoma brucei transcription factor BTF3, putative 0.005 0.0115 0.0599
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0021 0.001 0.0009
Onchocerca volvulus 0.0072 0.0194 0.0454
Giardia lamblia Cathepsin B precursor 0.0509 0.1773 0.4066
Brugia malayi hypothetical protein 0.0112 0.0338 0.061
Brugia malayi MH1 domain containing protein 0.0033 0.0051 0.0092
Brugia malayi Bloom's syndrome protein homolog 0.004 0.0076 0.0137
Brugia malayi Pre-SET motif family protein 0.0894 0.3167 0.5709
Loa Loa (eye worm) TAR-binding protein 0.0458 0.159 0.3087
Brugia malayi jmjC domain containing protein 0.0105 0.0313 0.0564
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0121 0.0531
Schistosoma mansoni nuclear hormone receptor 0.01 0.0295 0.0418
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0199 0.0654 0.3106
Brugia malayi hypothetical protein 0.01 0.0295 0.0531
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0005
Brugia malayi M-phase phosphoprotein, mpp8 0.0027 0.003 0.0054
Schistosoma mansoni DNA polymerase eta 0.0076 0.0208 0.0293
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Brugia malayi mbt repeat family protein 0.0034 0.0057 0.0103
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.0608 0.1401
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0059 0.0147 0.0147
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0028 0.0033 0.0124
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0011
Giardia lamblia Cathepsin B precursor 0.0094 0.0271 0.0585
Echinococcus multilocularis geminin 0.1928 0.691 0.691
Echinococcus granulosus cpg binding protein 0.0076 0.0207 0.0291
Plasmodium vivax vivapain-1 0.0187 0.0608 0.5471
Toxoplasma gondii TIM10 family protein, putative 0.0075 0.0203 0.1094
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0028 0.011
Schistosoma mansoni myelin transcription factor 1 myt1 0.0039 0.0074 0.0098
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0094 0.0271 0.0623
Brugia malayi hypothetical protein 0.0027 0.003 0.0054
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0023 0.0023
Plasmodium falciparum heterochromatin protein 1 0.0027 0.003 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0271 0.0623
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Onchocerca volvulus 0.0074 0.0199 0.0466
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.008 0.0183
Giardia lamblia Cathepsin L precursor 0.0094 0.0271 0.0585
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0015 0.0015
Brugia malayi MH1 domain containing protein 0.0059 0.0147 0.0265
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Schistosoma mansoni coup transcription factor 0.0212 0.0701 0.1006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0112 0.0338 0.0481
Echinococcus granulosus transcription factor btf3 0.005 0.0115 0.0157
Toxoplasma gondii preprocathepsin c precursor, putative 0.0094 0.0271 0.1476
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0039 0.0074 0.0134
Trypanosoma cruzi transcription factor btf3, putative 0.005 0.0115 0.0222
Echinococcus multilocularis mothers against decapentaplegic 6 0.0027 0.0028 0.0028
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0028 0.0054
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0018 0.0017
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0013 0.0009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0025 0.0024 0.0067
Onchocerca volvulus 0.0022 0.0011 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.0212 0.0701 0.1006
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.0085 0.0114
Brugia malayi SET domain containing protein 0.0033 0.0052 0.0094
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0017 0.0043
Giardia lamblia Cathepsin L precursor 0.0094 0.0271 0.0585
Loa Loa (eye worm) hypothetical protein 0.0076 0.0208 0.0388
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0323 0.1102 0.1102
Leishmania major alpha glucosidase II subunit, putative 0.0109 0.0328 0.1847
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0154 0.049 0.07
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0024 0.0018 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.014 0.0439 0.2432
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0109 0.0328 0.0756
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.01 0.0295 0.0295
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.0208 0.0405
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0027 0.003 0.0107
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0188 0.0614 0.1416
Brugia malayi Bromodomain containing protein 0.0067 0.0174 0.0314
Echinococcus granulosus dna polymerase eta 0.0076 0.0208 0.0293
Loa Loa (eye worm) RNA binding protein 0.0458 0.159 0.3087
Echinococcus granulosus lipoxygenase domain containing protein 0.0028 0.0035 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0087 0.0201
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.001 0.0005
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0085 0.0194
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0028 0.0032
Schistosoma mansoni polycystin 1-related 0.0028 0.0035 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Mycobacterium tuberculosis Probable lipase LipD 0.0034 0.0054 0.0211
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.008 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Trichomonas vaginalis Heterochromatin protein, putative 0.0027 0.003 0.0067
Plasmodium falciparum serine repeat antigen 3 0.0094 0.0271 0.2383
Loa Loa (eye worm) hypothetical protein 0.0624 0.2191 0.4261
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0021 0.001 0.0021
Schistosoma mansoni glutaminase 0.0187 0.0611 0.0875
Entamoeba histolytica cysteine proteinase, putative 0.0323 0.1102 0.2542
Brugia malayi Nuclear hormone receptor-like 1 0.0212 0.0701 0.1263
Trypanosoma cruzi cysteine peptidase, putative 0.0187 0.0608 0.1184
Entamoeba histolytica hypothetical protein 0.0027 0.003 0.0067
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.013 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.004 0.0076 0.013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0054 0.007
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0005
Mycobacterium tuberculosis Possible hydrolase 0.0046 0.01 0.0431
Entamoeba histolytica cysteine protease, putative 0.0323 0.1102 0.2542
Echinococcus granulosus Polycystic kidney disease protein 0.0028 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0055 0.0132 0.0238
Echinococcus multilocularis SAM and MBT domain containing protein 0.0034 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0037 0.0161
Brugia malayi Pyruvate kinase, muscle isozyme 0.0024 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.005
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0051
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0288 0.0975 0.1403
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0271 0.0623
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0028 0.01
Loa Loa (eye worm) heterochromatin protein 1 0.0164 0.0527 0.1011
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0093 0.0269 0.0507
Loa Loa (eye worm) inositol-1 0.0028 0.0033 0.0045
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.051
Schistosoma mansoni smad1 5 8 and 0.0059 0.0147 0.0204
Mycobacterium ulcerans lipase LipD 0.0034 0.0054 0.0211
Schistosoma mansoni microtubule-associated protein tau 0.1605 0.5739 0.8303
Trichomonas vaginalis chromobox protein, putative 0.0099 0.0291 0.0671
Loa Loa (eye worm) nuclear receptor NHR-67 0.01 0.0295 0.0557
Giardia lamblia Encystation-specific protease 0.0094 0.0271 0.0585
Brugia malayi Calcitonin receptor-like protein seb-1 0.091 0.3226 0.5816
Schistosoma mansoni retinoic acid receptor RXR 0.0212 0.0701 0.1006
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0011 0.0006
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.001 0.0005
Echinococcus multilocularis cathepsin L cysteine protease 0.0323 0.1102 0.1102
Echinococcus multilocularis tar DNA binding protein 0.0458 0.159 0.159
Treponema pallidum fructose-bisphosphate aldolase 0.1216 0.4334 1
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0323 0.1102 0.1102
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0509 0.1773 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0024 0.0018 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0094 0.0271 0.0623
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0199 0.0654 0.3687
Schistosoma mansoni smad1 5 8 and 0.0059 0.0147 0.0204
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0025 0.0023 0.0024
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0212 0.0701 0.1702
Giardia lamblia Cathepsin L precursor 0.0094 0.0271 0.0585
Loa Loa (eye worm) intermediate filament protein 0.0049 0.0111 0.0198
Echinococcus granulosus cathepsin L 0.0094 0.0271 0.0383
Entamoeba histolytica transcription factor BTF3, putative 0.005 0.0115 0.0263
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0199 0.0909
Echinococcus granulosus mothers against decapentaplegic 2 0.0027 0.0028 0.0032
Echinococcus granulosus endonuclease exonuclease phosphatase 0.014 0.044 0.0629
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0037 0.0161
Mycobacterium leprae Probable lipase LipE 0.0034 0.0054 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.001 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0212 0.0701 0.07
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0075 0.0203 0.1767
Schistosoma mansoni hypothetical protein 0.0288 0.0975 0.1403
Echinococcus multilocularis transcription factor btf3 0.005 0.0115 0.0114
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0323 0.1102 1
Brugia malayi hypothetical protein 0.1143 0.4069 0.7335
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0041 0.0081 0.0081
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Giardia lamblia Hypothetical protein 0.0046 0.01 0.019
Brugia malayi calpain family protein 1 0.0052 0.012 0.0217
Schistosoma mansoni transcription factor btf3 0.005 0.0115 0.0157
Giardia lamblia Cathepsin B precursor 0.0094 0.0271 0.0585
Schistosoma mansoni hypothetical protein 0.0288 0.0975 0.1403
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.0132 1
Brugia malayi mothers against decapentaplegic homolog 3 0.0027 0.0028 0.0051
Leishmania major cysteine peptidase A (CPA) 0.0323 0.1102 0.6213
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0064 0.0162 0.0293
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0187 0.0608 0.3394
Schistosoma mansoni cathepsin s 0.0093 0.0269 0.0381
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0121 0.0531
Echinococcus multilocularis cathepsin L 0.0094 0.0271 0.027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0085 0.0164
Echinococcus granulosus snurportin 1 0.0248 0.0831 0.1194
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0389 0.1341 0.2615
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0087
Onchocerca volvulus 0.0323 0.1102 0.2691
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0025 0.0024 0.0127
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0188 0.0614 0.0881
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.0608 0.1401
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0109 0.0328 0.0622
Brugia malayi G-protein alpha subunit 0.0021 0.001 0.0017
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0041 0.0081 0.0108
Plasmodium vivax unspecified product 0.0187 0.0608 0.5471
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0027 0.003 0.0054
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.008 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Brugia malayi hypothetical protein 0.0028 0.0035 0.0063
Loa Loa (eye worm) hypothetical protein 0.0141 0.0442 0.0845
Schistosoma mansoni chromobox protein 0.0027 0.003 0.0034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0094 0.0271 0.051
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0017 0.0033
Onchocerca volvulus 0.0034 0.0057 0.0116
Loa Loa (eye worm) helicase 0.0027 0.003 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0212 0.0701 0.135
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.011 0.015
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.013 0.0179
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0594 0.2083 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0011 0.002
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0094 0.0271 0.0383
Schistosoma mansoni hypothetical protein 0.0064 0.0162 0.0226
Schistosoma mansoni alpha-glucosidase 0.0424 0.1467 0.2116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0212 0.0701 0.135
Giardia lamblia Cathepsin L precursor 0.0094 0.0271 0.0585
Plasmodium vivax vivapain-2 0.0323 0.1102 1
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Toxoplasma gondii cathepsin B 0.0509 0.1773 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0028 0.0162
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0028 0.0101
Trypanosoma cruzi cysteine peptidase, putative 0.0323 0.1102 0.2148
Trypanosoma cruzi trypanothione reductase, putative 0.0073 0.0198 0.0385
Echinococcus multilocularis microtubule associated protein 2 0.1605 0.5739 0.5739
Brugia malayi cathepsin L-like precursor 0.023 0.0765 0.1379
Giardia lamblia PHD finger protein 15 0.0082 0.023 0.049
Schistosoma mansoni lamin 0.0049 0.0111 0.0152
Brugia malayi cathepsin F-like cysteine proteinase 0.0094 0.0271 0.0488
Echinococcus granulosus thyroid hormone receptor alpha 0.01 0.0295 0.0418
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0075 0.0203 0.1094
Echinococcus granulosus intermediate filament protein 0.0049 0.0111 0.0152
Schistosoma mansoni transcription factor LCR-F1 0.0196 0.064 0.0918
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0011 0.002
Echinococcus granulosus RUN 0.0028 0.0035 0.0042
Echinococcus multilocularis ecdysone induced protein 78C 0.0212 0.0701 0.07
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0094 0.0271 0.0383
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0028 0.0033 0.0106
Loa Loa (eye worm) cysteine protease 0.0323 0.1102 0.2134
Plasmodium vivax ataxin-2 like protein, putative 0.0092 0.0263 0.2317
Schistosoma mansoni hypothetical protein 0.0196 0.064 0.0918
Echinococcus multilocularis cathepsin L cysteine protease 0.0323 0.1102 0.1102
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0323 0.1102 0.2542
Echinococcus granulosus cathepsin L cysteine protease 0.0187 0.0608 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0765 0.1764
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0212 0.0701 0.1263
Loa Loa (eye worm) glutathione reductase 0.0073 0.0198 0.0368
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0024 0.0018 0.0052
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0094 0.0271 0.0383
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0085 0.0357
Mycobacterium ulcerans glutaminase 0.0187 0.0611 0.2896
Schistosoma mansoni jumonji domain containing protein 0.0214 0.0706 0.1014
Trypanosoma cruzi PAB1-binding protein , putative 0.0092 0.0263 0.0513
Onchocerca volvulus 0.0028 0.0035 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Loa Loa (eye worm) hypothetical protein 0.0055 0.0132 0.0238
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.051
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.001 0.0009
Brugia malayi hypothetical protein 0.0624 0.2191 0.3949
Echinococcus granulosus cathepsin L cysteine proteinase 0.0323 0.1102 0.1587
Loa Loa (eye worm) runx1 0.0078 0.0216 0.0402
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0028 0.0028
Brugia malayi hypothetical protein 0.0196 0.064 0.1154
Echinococcus granulosus microtubule associated protein 2 0.1605 0.5739 0.8303
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.0608 0.1401
Giardia lamblia Cathepsin B precursor 0.0094 0.0271 0.0585
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0094 0.0271 0.0383
Schistosoma mansoni aldehyde dehydrogenase 0.0199 0.0654 0.0938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Schistosoma mansoni lipoxygenase 0.0075 0.0205 0.0288
Schistosoma mansoni loxhd1 0.0028 0.0035 0.0042
Schistosoma mansoni smad1 5 8 and 0.0059 0.0147 0.0204
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1216 0.4334 1
Echinococcus multilocularis lamin 0.0049 0.0111 0.0111
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0021 0.001 0.0021
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0212 0.0701 0.1006
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0034 0.0054 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Schistosoma mansoni tar DNA-binding protein 0.0458 0.159 0.2294
Echinococcus granulosus TGF beta signal transducer SmadC 0.0059 0.0147 0.0204
Schistosoma mansoni tar DNA-binding protein 0.0458 0.159 0.2294
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0212 0.0701 0.1006
Mycobacterium ulcerans arylsulfatase AtsD 0.0046 0.01 0.0431
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0076
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0288 0.0975 0.0974
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.013 0.0401 0.2216
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0017 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0094 0.0271 0.0623
Plasmodium vivax unspecified product 0.0093 0.0269 0.2371
Trichomonas vaginalis pyruvate kinase, putative 0.0024 0.0018 0.0041
Brugia malayi Inositol-1 0.0028 0.0033 0.0059
Brugia malayi nuclear receptor NHR-88 0.0212 0.0701 0.1263
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0109 0.0328 0.0756
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0009 0.0016
Trichomonas vaginalis inositol monophosphatase, putative 0.0028 0.0033 0.0074
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0009 0.0019
Schistosoma mansoni sex comb on midleg homolog 0.0034 0.0057 0.0073
Schistosoma mansoni thyroid hormone receptor 0.0212 0.0701 0.1006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0188 0.0614 0.1197
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Trichomonas vaginalis chromobox protein, putative 0.0099 0.0291 0.0671
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0105
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0039 0.0074 0.0134
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.0199 0.0909
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.023 0.0765 0.1475
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0271 0.0623
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0144 0.0453 0.0647
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0029 0.0172
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0094 0.0271 0.2383
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.008 0.0144
Brugia malayi nuclear hormone receptor family member odr-7 0.01 0.0295 0.0531
Schistosoma mansoni hypothetical protein 0.1928 0.691 1
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Echinococcus granulosus survival motor neuron protein 1 0.0192 0.0627 0.0899
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0132 0.0584
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0054 0.0257
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0023 0.0023
Giardia lamblia Cathepsin L-like protease 0.0094 0.0271 0.0585
Schistosoma mansoni alpha glucosidase 0.0109 0.0328 0.0466
Onchocerca volvulus 0.0034 0.0054 0.011
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0021 0.001 0.0021
Brugia malayi calpain family protein 1 0.0052 0.012 0.0217
Echinococcus granulosus cathepsin l cysteine peptidase 0.0323 0.1102 0.1587
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0085 0.0429
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0019
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0064 0.0162 0.0293
Leishmania major pyruvate kinase 0.0024 0.0018 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0094 0.0271 0.0623
Leishmania major cathepsin L-like protease 0.0323 0.1102 0.6213
Plasmodium falciparum serine repeat antigen 4 0.0094 0.0271 0.2383
Echinococcus multilocularis cathepsin b 0.1436 0.5129 0.5129
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0094 0.0271 0.0623
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0064 0.0162 0.0293
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.005 0.0079
Brugia malayi PHD-finger family protein 0.0025 0.0022 0.0041
Brugia malayi hypothetical protein 0.0046 0.01 0.018
Brugia malayi MH2 domain containing protein 0.0059 0.0147 0.0265
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0109 0.0328 0.1801
Mycobacterium tuberculosis Conserved protein 0.0034 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.0192 0.0627 0.1206
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0024 0.0018 0.0099
Loa Loa (eye worm) nuclear receptor nhr-7B 0.01 0.0295 0.0557
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0269 0.0906 0.0906
Mycobacterium tuberculosis Probable sulfatase 0.0046 0.01 0.0431
Schistosoma mansoni hypothetical protein 0.0039 0.0074 0.0098
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0024 0.0018 0.0036
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0028 0.0032
Brugia malayi Nuclear hormone receptor E75 0.01 0.0295 0.0531
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0112 0.0338 0.0481
Echinococcus multilocularis neuropeptide receptor A26 0.0382 0.1314 0.1314
Onchocerca volvulus 0.007 0.0185 0.0431
Echinococcus granulosus tumor protein p63 0.0476 0.1655 0.2388
Brugia malayi PHD-finger family protein 0.0082 0.023 0.0414
Plasmodium vivax unspecified product 0.0094 0.0271 0.2383
Onchocerca volvulus 0.0323 0.1102 0.2691
Loa Loa (eye worm) pigment dispersing factor receptor c 0.091 0.3226 0.6284
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0025 0.0024 0.0047
Plasmodium vivax glutathione reductase, putative 0.0073 0.0198 0.1718
Echinococcus multilocularis snurportin 1 0.0248 0.0831 0.083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.0271 0.0623
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0024 0.0018 0.0069
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0025 0.0024 0.0088
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0028 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0212 0.0701 0.1006
Trichomonas vaginalis chromobox protein, putative 0.0027 0.003 0.0067
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0099 0.0291 0.0694
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0115 0.0263
Echinococcus multilocularis polycomb protein SCMH1 0.0034 0.0057 0.0057
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0034 0.0054 0.0211
Trypanosoma cruzi polo-like protein kinase, putative 0.0127 0.0391 0.0762
Brugia malayi nuclear receptor NHR-67 0.01 0.0295 0.0531
Echinococcus granulosus lamin 0.0049 0.0111 0.0152
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0094 0.0271 0.2383
Echinococcus granulosus cathepsin L 0.0187 0.0608 0.0871
Leishmania major hypothetical protein, conserved 0.0034 0.0054 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0271 0.0623
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0085 0.0153
Brugia malayi cathepsin Z-like cysteine proteinase 0.0094 0.0271 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0094 0.0271 0.0383
Onchocerca volvulus 0.1143 0.4069 1
Schistosoma mansoni hypothetical protein 0.0028 0.0035 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0199 0.0909
Echinococcus granulosus pyruvate kinase 0.0024 0.0018 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.0082 0.023 0.1243
Echinococcus multilocularis histone acetyltransferase MYST2 0.0039 0.0074 0.0074
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0025 0.0024 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0115 0.0263
Echinococcus multilocularis chromobox protein 1 0.0164 0.0527 0.0527
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0188 0.0614 0.0881
Echinococcus granulosus histone lysine methyltransferase setb 0.0144 0.0453 0.0647
Echinococcus granulosus SAM and MBT domain containing protein 0.0034 0.0057 0.0073
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0054 0.0124
Entamoeba histolytica cysteine protease, putative 0.0094 0.0271 0.0623
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0196 0.064 0.0918
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0013 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0192 0.0627 0.0627
Onchocerca volvulus 0.01 0.0295 0.0702
Schistosoma mansoni tar DNA-binding protein 0.0458 0.159 0.2294
Brugia malayi Bromodomain containing protein 0.0032 0.0049 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Giardia lamblia Cysteine protease 0.0094 0.0271 0.0585
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0055 0.013 0.0179
Brugia malayi cathepsin F-like cysteine proteinase 0.0093 0.0269 0.0486
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.01 0.0295 0.0295
Echinococcus multilocularis calpain family protein 1, d 0.0036 0.0064 0.0064
Plasmodium falciparum thioredoxin reductase 0.0073 0.0198 0.1718
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0212 0.0701 0.1263
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0085 0.0357
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0212 0.0701 0.1006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0199 0.0909
Schistosoma mansoni hypothetical protein 0.0626 0.2197 0.3173
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0186 0.0606 0.2874
Loa Loa (eye worm) hypothetical protein 0.0112 0.0338 0.0642
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0094 0.0271 0.0623
Mycobacterium tuberculosis Conserved protein 0.0034 0.0054 0.0211
Schistosoma mansoni cpg binding protein 0.0076 0.0207 0.0291
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Mycobacterium tuberculosis Probable dehydrogenase 0.0167 0.0538 0.2547
Schistosoma mansoni hypothetical protein 0.0288 0.0975 0.1403
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.0199 0.0909
Brugia malayi Bromodomain containing protein 0.0084 0.0237 0.0427
Brugia malayi photoreceptor-specific nuclear receptor 0.0212 0.0701 0.1263
Brugia malayi beta-lactamase family protein 0.0034 0.0054 0.0098
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0087
Mycobacterium tuberculosis Probable hydrolase 0.0034 0.0054 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0199 0.0654 0.3651
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.0208 0.0376
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0052 0.012 0.0165
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.01 0.0295 0.0418
Loa Loa (eye worm) ctsf protein 0.0323 0.1102 0.2134
Echinococcus multilocularis lipoxygenase domain containing protein 0.0028 0.0035 0.0035
Schistosoma mansoni pyruvate kinase 0.0024 0.0018 0.0018
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0127 0.0391 0.0745
Onchocerca volvulus Protein ultraspiracle homolog 0.0212 0.0701 0.1702
Leishmania major hypothetical protein, conserved 0.0092 0.0263 0.1483
Echinococcus granulosus pyruvate kinase 0.0024 0.0018 0.0018
Plasmodium vivax pyruvate kinase, putative 0.0024 0.0018 0.0071
Echinococcus multilocularis muscleblind protein 0.0243 0.0811 0.0811
Schistosoma mansoni lamin 0.0049 0.0111 0.0152
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1436 0.5129 0.7419
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0054 0.0124
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0212 0.0701 0.1006
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0094 0.0271 0.0383
Echinococcus granulosus Smad4 0.0059 0.0147 0.0204
Echinococcus granulosus PHD finger protein rhinoceros 0.0082 0.023 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Giardia lamblia Fructose-bisphosphate aldolase 0.1216 0.4334 1
Schistosoma mansoni aldehyde dehydrogenase 0.0199 0.0654 0.0938
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0027 0.003 0.0109
Plasmodium falciparum pyruvate kinase 0.0024 0.0018 0.0071
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0269 0.0906 0.1304
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Loa Loa (eye worm) hypothetical protein 0.0092 0.0263 0.0496
Brugia malayi Cathepsin L-like precursor 0.0323 0.1102 0.1986
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0025 0.0024 0.0532
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0021
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Echinococcus granulosus nuclear receptor nhr 48 0.01 0.0295 0.0418
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0005
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.001 0.0009
Plasmodium falciparum serine repeat antigen 9 0.0094 0.0271 0.2383
Brugia malayi Papain family cysteine protease containing protein 0.0187 0.0608 0.1095
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.008 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0094 0.0271 0.0623
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0028 0.0036
Onchocerca volvulus Huntingtin homolog 0.0099 0.0292 0.0696
Giardia lamblia Cathepsin B precursor 0.0509 0.1773 0.4066
Trypanosoma cruzi cysteine proteinase, putative 0.0187 0.0608 0.1184
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0199 0.0458
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.005 0.0063
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0212 0.0701 0.1006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Brugia malayi exodeoxyribonuclease III family protein 0.0024 0.0018 0.0033
Schistosoma mansoni cathepsin B (C01 family) 0.0094 0.0271 0.0383
Trypanosoma cruzi trypanothione reductase, putative 0.0025 0.0024 0.0047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.0401 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0105
Giardia lamblia NADH oxidase lateral transfer candidate 0.0025 0.0024 0.0014
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0021 0.001 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0045 0.0316
Leishmania major cathepsin L-like protease 0.0483 0.1678 0.9465
Loa Loa (eye worm) transcription factor SMAD2 0.0871 0.3082 0.6003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Brugia malayi beta-lactamase family protein 0.0034 0.0054 0.0098
Onchocerca volvulus Huntingtin homolog 0.0099 0.0292 0.0696
Loa Loa (eye worm) mbt repeat family protein 0.0034 0.0057 0.0092
Loa Loa (eye worm) hypothetical protein 0.0039 0.0074 0.0126
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0085 0.0357
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0094 0.0271 0.0585
Loa Loa (eye worm) CXXC zinc finger family protein 0.007 0.0187 0.0347
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0212 0.0701 0.1006
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0025 0.0023 0.0112
Echinococcus multilocularis transcription factor Dp 1 0.0109 0.0327 0.0327
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.003 0.0067
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0028 0.0101
Loa Loa (eye worm) oxidoreductase 0.0022 0.0011 0.0002
Brugia malayi Cathepsin L-like precursor 0.0093 0.0269 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0458 0.159 0.2294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0212 0.0701 0.135
Entamoeba histolytica serine/threonine protein kinase, putative 0.0127 0.0391 0.0902
Toxoplasma gondii NAC domain-containing protein 0.005 0.0115 0.059
Trypanosoma cruzi cysteine proteinase, putative 0.0187 0.0608 0.1184
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0075 0.0203 0.0367
Treponema pallidum NADH oxidase 0.0025 0.0024 0.0014
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0094 0.0271 0.2383
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0187 0.0608 0.0871
Toxoplasma gondii cathepsin CPC1 0.0094 0.0271 0.1476
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0028 0.0033 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.0199 0.0458
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0028 0.0032
Echinococcus multilocularis Chromobox protein 3 0.0027 0.003 0.0029
Schistosoma mansoni hypothetical protein 0.0214 0.0707 0.1015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.0081
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0188 0.0614 0.0614
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0212 0.0701 0.1006
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Plasmodium falciparum serine repeat antigen 2 0.0094 0.0271 0.2383
Mycobacterium tuberculosis Probable oxidoreductase 0.0186 0.0606 0.2874
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0094 0.0271 0.0585
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.0057
Brugia malayi isocitrate dehydrogenase 0.0025 0.0023 0.0041
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.0085 0.0114
Echinococcus multilocularis pyruvate kinase 0.0024 0.0018 0.0018
Trichomonas vaginalis sucrase-isomaltase, putative 0.0109 0.0328 0.0756
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0024 0.0018 0.0034
Echinococcus granulosus beta LACTamase domain containing family member 0.0034 0.0054 0.007
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0212 0.0701 0.07
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0087
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0094 0.0271 0.2383
Giardia lamblia Cathepsin L precursor 0.0094 0.0271 0.0585
Echinococcus granulosus lipoxygenase domain containing protein 0.0028 0.0035 0.0042
Onchocerca volvulus 0.0212 0.0701 0.1702
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0013 0.0012
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0046 0.01 0.0229
Schistosoma mansoni ap endonuclease 0.0024 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Echinococcus granulosus Chromo domain 0.0027 0.003 0.0034
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0027 0.003 0.0175
Onchocerca volvulus 0.0323 0.1102 0.2691
Leishmania major trypanothione reductase 0.0073 0.0198 0.1114
Plasmodium vivax hypothetical protein, conserved 0.0027 0.003 0.0175
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0654 0.3106
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0027 0.003 0.0029
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0009 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0212 0.0701 0.1263
Plasmodium falciparum serine repeat antigen 1 0.0094 0.0271 0.2383
Onchocerca volvulus 0.0094 0.0271 0.0643
Echinococcus granulosus bloom syndrome protein 0.004 0.0076 0.0101
Echinococcus multilocularis Protein lozenge 0.0078 0.0216 0.0215
Trypanosoma cruzi cruzipain precursor, putative 0.0093 0.0269 0.0524
Mycobacterium tuberculosis Conserved protein 0.0034 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0037 0.0161
Plasmodium falciparum ataxin-2 like protein, putative 0.0092 0.0263 0.2317
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.0076 0.0174
Brugia malayi Cathepsin L-like cysteine proteinase 0.023 0.0765 0.1379
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0027 0.0028 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0212 0.0701 0.1263
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0011 0.0009
Brugia malayi Nuclear hormone receptor E75 0.01 0.0295 0.0531
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1216 0.4334 1
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0199 0.1119
Entamoeba histolytica cysteine protease, putative 0.0094 0.0271 0.0623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0087 0.0201
Plasmodium vivax serine-repeat antigen (SERA) 0.0094 0.0271 0.2383
Schistosoma mansoni sex comb on midleg homolog 0.0034 0.0057 0.0073
Brugia malayi Cathepsin L-like precursor 0.0323 0.1102 0.1986
Echinococcus granulosus FTZ F1 alpha 0.0212 0.0701 0.1006
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.0085 0.0084
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0051
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0061 0.0139
Brugia malayi Isocitrate dehydrogenase 0.0025 0.0023 0.0041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.01 0.0295 0.0295
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0027 0.003 0.0117
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0594 0.2083 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0212 0.0701 0.07
Echinococcus multilocularis RUN 0.0028 0.0035 0.0035
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0094 0.0271 0.0585
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0025 0.0024 0.4362
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Echinococcus granulosus GPCR family 2 0.0288 0.0975 0.1403
Echinococcus multilocularis cysteine protease 0.0323 0.1102 0.1102
Onchocerca volvulus 0.0156 0.0499 0.1204
Echinococcus granulosus lysosomal alpha glucosidase 0.0493 0.1716 0.2476
Brugia malayi AF-10 protein 0.0027 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0074 0.0199 0.037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0047
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0085 0.0164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.01 0.0295 0.0295
Giardia lamblia Hypothetical protein 0.0094 0.0271 0.0585
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0099 0.0292 0.0552
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.01 0.0295 0.0702
Echinococcus multilocularis zinc finger protein 0.002 0.0006 0.0006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0188 0.0614 0.1197
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0103 0.02
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0011 0.001
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.0085 0.0114
Brugia malayi RNA binding protein 0.0458 0.159 0.2866
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.008 0.0154
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0127 0.0391 0.0558
Schistosoma mansoni lipoxygenase 0.0127 0.039 0.0556
Brugia malayi hypothetical protein 0.01 0.0295 0.0531
Loa Loa (eye worm) beta-lactamase 0.0034 0.0054 0.0087
Echinococcus multilocularis dna polymerase eta 0.0076 0.0208 0.0208
Plasmodium vivax JmjC domain containing protein 0.0027 0.0028 0.0162
Giardia lamblia Cathepsin L precursor 0.0094 0.0271 0.0585
Loa Loa (eye worm) calpain family protein 1 0.0036 0.0064 0.0107
Echinococcus multilocularis lysosomal alpha glucosidase 0.0493 0.1716 0.1715
Loa Loa (eye worm) cathepsin B 0.0509 0.1773 0.3445
Onchocerca volvulus 0.0034 0.0054 0.011
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0199 0.0654 0.0938
Entamoeba histolytica cysteine protease, putative 0.0094 0.0271 0.0623
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Schistosoma mansoni Smad4 0.0027 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.023 0.0765 0.1475
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.051
Brugia malayi Cathepsin L-like precursor 0.0323 0.1102 0.1986
Loa Loa (eye worm) jmjC domain-containing protein 0.0105 0.0313 0.0592
Toxoplasma gondii isocitrate dehydrogenase 0.0025 0.0023 0.007
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0011 0.0023
Loa Loa (eye worm) doublecortin family protein 0.0028 0.0035 0.005
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0094 0.0271 0.2383
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0025 0.0023 0.0024
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0075 0.0203 0.1767
Schistosoma mansoni inositol monophosphatase 0.0028 0.0033 0.0038
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0049 0.0111 0.0198
Loa Loa (eye worm) hypothetical protein 0.0055 0.0132 0.0238
Echinococcus multilocularis Polycystic kidney disease protein 0.0028 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0027 0.003 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Brugia malayi nuclear receptor NHR-88 0.01 0.0295 0.0531
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0509 0.1773 0.3457
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0025 0.0024 0.0088
Leishmania major basic transcription factor 3a, putative 0.005 0.0115 0.0644
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0025 0.0024 0.0127
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0288 0.0975 0.0974
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0026 0.0028 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0025 0.0024 0.0088
Trichomonas vaginalis set domain proteins, putative 0.1017 0.3613 0.8337
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0087 0.0201
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0212 0.0701 0.135
Brugia malayi Pre-SET motif family protein 0.013 0.0401 0.0723
Brugia malayi MH2 domain containing protein 0.0027 0.0028 0.0051
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1436 0.5129 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.01 0.0295 0.0531
Mycobacterium tuberculosis Probable reductase 0.0167 0.0538 0.2547
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0025 0.0022 0.0055
Echinococcus multilocularis lysosomal alpha glucosidase 0.0493 0.1716 0.1715
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0061 0.0139
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Trypanosoma brucei cysteine peptidase C (CPC) 0.0509 0.1773 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.005
Echinococcus granulosus dnaJ subfamily B 0.0626 0.2197 0.3173
Loa Loa (eye worm) latrophilin receptor protein 2 0.0288 0.0975 0.1885
Loa Loa (eye worm) MH1 domain-containing protein 0.0059 0.0147 0.0268
Loa Loa (eye worm) hypothetical protein 0.0064 0.0162 0.0299
Brugia malayi CXXC zinc finger family protein 0.007 0.0187 0.0337
Echinococcus multilocularis calpain A 0.0055 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0271 0.0623
Trypanosoma cruzi pyruvate kinase 2, putative 0.0024 0.0018 0.0035
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0323 0.1102 0.2134
Trichomonas vaginalis glutathione reductase, putative 0.0025 0.0024 0.0055
Echinococcus multilocularis bloom syndrome protein 0.004 0.0076 0.0076
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0055 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0072 0.0194 0.036
Trypanosoma brucei unspecified product 0.0029 0.0037 0.0161
Brugia malayi Importin beta-1 subunit 0.0023 0.0017 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Echinococcus multilocularis Chromo domain 0.0027 0.003 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0094 0.0271 0.0488
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0497 0.1732 0.3364
Brugia malayi hypothetical protein 0.0057 0.014 0.0253
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0025 0.0024 0.0078
Trichomonas vaginalis glutaminase, putative 0.0187 0.0611 0.1408
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.001 0.0005
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0039 0.0074 0.0098
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0011 0.0019
Echinococcus multilocularis neutral alpha glucosidase AB 0.0109 0.0328 0.0328
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0017
Plasmodium vivax heterochromatin protein 1, putative 0.0027 0.003 0.0175
Schistosoma mansoni cathepsin F (C01 family) 0.0323 0.1102 0.1587
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0025 0.0023 0.0043
Echinococcus granulosus chromobox protein 1 0.0164 0.0527 0.0755
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Brugia malayi beta-lactamase 0.0034 0.0054 0.0098
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0328 0.0639
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0164 0.0527 0.1216
Brugia malayi beta-NAC-like protein 0.005 0.0115 0.0207
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0028 0.0032
Leishmania major DNA polymerase eta, putative 0.0047 0.0103 0.058
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.008 0.0154
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0094 0.0271 0.2383
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0493 0.1716 0.3332
Loa Loa (eye worm) hypothetical protein 0.0622 0.2184 0.4248
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0028 0.0028
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0212 0.0701 0.07
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0028 0.0036
Onchocerca volvulus Pyruvate kinase homolog 0.0024 0.0018 0.0022
Schistosoma mansoni hypothetical protein 0.0288 0.0975 0.1403
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.003 0.0041 0.0041
Onchocerca volvulus Serine\/threonine kinase homolog 0.0127 0.0391 0.094
Echinococcus granulosus dna polymerase kappa 0.0042 0.0085 0.0114
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Loa Loa (eye worm) hypothetical protein 0.0323 0.1102 0.2134
Brugia malayi F/Y-rich N-terminus family protein 0.0055 0.013 0.0235
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0212 0.0701 0.07
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Schistosoma mansoni nuclear receptor 0.01 0.0295 0.0418
Echinococcus granulosus histone acetyltransferase MYST2 0.0039 0.0074 0.0098
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0085 0.0164
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0094 0.0271 0.2383
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0025 0.0024 0.0067
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0051
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0212 0.0701 0.1263
Trypanosoma cruzi cruzipain precursor, putative 0.0483 0.1678 0.3272
Schistosoma mansoni cathepsin F (C01 family) 0.023 0.0765 0.1099
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0064 0.0162 0.0862
Mycobacterium ulcerans arylsulfatase AtsD 0.0046 0.01 0.0431
Schistosoma mansoni hypothetical protein 0.0248 0.0831 0.1194
Echinococcus multilocularis expressed protein 0.0075 0.0203 0.0203
Plasmodium vivax vivapain-3 0.0187 0.0608 0.5471
Mycobacterium ulcerans beta-lactamase 0.0034 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.0288 0.0975 0.1885
Schistosoma mansoni thyroid hormone receptor 0.0212 0.0701 0.1006
Schistosoma mansoni survival motor neuron protein 0.0039 0.0074 0.0098
Trichomonas vaginalis esterase, putative 0.0034 0.0054 0.0124
Leishmania major DNA polymerase kappa, putative 0.0042 0.0085 0.0474
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.008 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Echinococcus granulosus peregrin 0.0084 0.0237 0.0334
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0017
Trypanosoma cruzi pyruvate kinase 2, putative 0.0024 0.0018 0.0035
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0094 0.0271 0.2383
Onchocerca volvulus 0.0624 0.2191 0.5373
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0046 0.01 0.0222
Onchocerca volvulus 0.0039 0.0074 0.0159
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0288 0.0975 0.1757
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Toxoplasma gondii exonuclease III APE 0.0024 0.0018 0.0043
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0033 0.018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.003 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0085 0.0429
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0196 0.064 0.064
Echinococcus granulosus transcription factor Dp 1 0.0109 0.0327 0.0465
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Echinococcus multilocularis beta LACTamase domain containing family member 0.0034 0.0054 0.0054
Leishmania major glycosyl hydrolase-like protein 0.0041 0.008 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.008 0.0183
Brugia malayi hypothetical protein 0.0028 0.0035 0.0063
Loa Loa (eye worm) ICD-1 protein 0.005 0.0115 0.0205
Brugia malayi Latrophilin receptor protein 2 0.0288 0.0975 0.1757
Loa Loa (eye worm) glutaminase 0.0187 0.0611 0.1174
Plasmodium vivax multidomain scavenger receptor, putative 0.0028 0.0035 0.0225
Echinococcus multilocularis expressed protein 0.0021 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0092 0.0266 0.0501
Brugia malayi MH1 domain containing protein 0.0033 0.0051 0.0092
Loa Loa (eye worm) fibroinase 0.0323 0.1102 0.2134
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0212 0.0701 0.1006
Brugia malayi nuclear hormone receptor 0.0212 0.0701 0.1263
Brugia malayi tailless protein 0.01 0.0295 0.0531
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0019
Mycobacterium ulcerans hydrolase 0.0046 0.01 0.0431
Brugia malayi orphan nuclear receptor NR2E1 0.01 0.0295 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Entamoeba histolytica hypothetical protein 0.0196 0.064 0.1476
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0186 0.0606 0.2874
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0483 0.1678 0.3272
Schistosoma mansoni chromobox protein 0.0164 0.0527 0.0755
Trichomonas vaginalis chromobox protein, putative 0.0164 0.0527 0.1216
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0497 0.1732 0.2499
Onchocerca volvulus 0.0323 0.1102 0.2691
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Schistosoma mansoni tar DNA-binding protein 0.0458 0.159 0.2294
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0654 0.3106
Brugia malayi Cathepsin L-like precursor 0.0323 0.1102 0.1986
Brugia malayi MH2 domain containing protein 0.0871 0.3082 0.5557
Brugia malayi Pyruvate kinase, M2 isozyme 0.0024 0.0018 0.0033
Onchocerca volvulus Cathepsin F homolog 0.0323 0.1102 0.2691
Schistosoma mansoni nuclear receptor 0.01 0.0295 0.0418
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0025 0.0024 0.0127
Loa Loa (eye worm) hypothetical protein 0.0041 0.008 0.0137
Onchocerca volvulus Cathepsin L homolog 0.0323 0.1102 0.2691
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0019
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0027 0.003 0.0034
Brugia malayi Sulfatase family protein 0.0046 0.01 0.018
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0328 0.0756
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.016 0.0367
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0018 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0085 0.0429
Leishmania major hypothetical protein, conserved 0.0027 0.0028 0.0157
Schistosoma mansoni cpg binding protein 0.0076 0.0207 0.0291
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0199 0.0909
Schistosoma mansoni alpha-glucosidase 0.0424 0.1467 0.2116
Schistosoma mansoni hypothetical protein 0.0041 0.0081 0.0108
Entamoeba histolytica hypothetical protein 0.0027 0.003 0.0067
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0025 0.0024 0.4362
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0054 0.0124
Loa Loa (eye worm) hypothetical protein 0.0046 0.01 0.0176
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0087 0.0201
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0021 0.001 0.0017
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0011 0.0057
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0035 0.0058 0.0438
Entamoeba histolytica cysteine proteinase 1, putative 0.0187 0.0608 0.1401
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0323 0.1102 0.2134
Loa Loa (eye worm) RecQ helicase 0.004 0.0076 0.0129
Schistosoma mansoni ap endonuclease 0.0024 0.0018 0.0017
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0025 0.0024 0.0067
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0054 0.0124
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1436 0.5129 0.7419
Echinococcus multilocularis cpg binding protein 0.0076 0.0207 0.0207
Brugia malayi Glycosyl hydrolases family 31 protein 0.0493 0.1716 0.3093
Loa Loa (eye worm) jmjC domain-containing protein 0.017 0.0546 0.1048
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Brugia malayi hypothetical protein 0.0092 0.0263 0.0475
Brugia malayi hypothetical protein 0.0021 0.001 0.0017
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0186 0.0606 0.2874
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0187 0.0608 0.3394
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Trypanosoma brucei pyruvate kinase 1 0.0024 0.0018 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0271 0.0623
Mycobacterium leprae conserved hypothetical protein 0.0034 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.0059 0.0147 0.0268
Onchocerca volvulus 0.0049 0.0111 0.0249
Plasmodium falciparum glutathione reductase 0.0073 0.0198 0.1718
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0025 0.0024 0.0127
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Brugia malayi cathepsin L-like cysteine proteinase 0.0094 0.0271 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0266 0.0612
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.0271 0.0623
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0054 0.0124
Brugia malayi Doublecortin family protein 0.0028 0.0035 0.0063
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.003 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.0059 0.0147 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0025 0.0024 0.0088
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0082 0.023 0.0324
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0167 0.0538 0.2547
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0288 0.0975 0.1403
Echinococcus granulosus lamin dm0 0.0049 0.0111 0.0152
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0199 0.0458
Echinococcus granulosus cathepsin b 0.1436 0.5129 0.7419
Echinococcus multilocularis neuropeptide s receptor 0.0382 0.1314 0.1314
Brugia malayi jmjC domain containing protein 0.0269 0.0906 0.1634
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0391 0.0558
Schistosoma mansoni chromobox protein 0.0027 0.003 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0085 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0212 0.0701 0.1263
Brugia malayi Cathepsin L-like precursor 0.0323 0.1102 0.1986
Onchocerca volvulus Bile acid receptor homolog 0.0212 0.0701 0.1702
Schistosoma mansoni smad 0.0059 0.0147 0.0204
Mycobacterium tuberculosis Probable esterase LipL 0.0034 0.0054 0.0211
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0025 0.0022 0.0055
Mycobacterium ulcerans hypothetical protein 0.0034 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.02 0.0654 0.1259
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0025 0.0023 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0028 0.0037
Trichomonas vaginalis chromobox protein, putative 0.0027 0.003 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.002
Echinococcus multilocularis pyruvate kinase 0.0024 0.0018 0.0018
Trichomonas vaginalis maltase-glucoamylase, putative 0.0109 0.0328 0.0756
Plasmodium vivax SET domain protein, putative 0.013 0.0401 0.3578
Loa Loa (eye worm) hypothetical protein 0.0074 0.0199 0.037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0212 0.0701 0.1263
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0011 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0199 0.0909
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.01 0.0295 0.0418
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0023 0.0023
Schistosoma mansoni RAR-like nuclear receptor 0.0212 0.0701 0.1006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.091 0.3226 0.5816
Echinococcus multilocularis Nuclear hormone receptor HR96 0.01 0.0295 0.0295
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0112 0.0338 0.0481
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0021 0.001 0.0005
Trypanosoma brucei unspecified product 0.0042 0.0085 0.0429
Brugia malayi Nuclear hormone receptor-like 1 0.0112 0.0338 0.061
Trypanosoma cruzi PAB1-binding protein , putative 0.0092 0.0263 0.0513
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0115 0.0263
Trichomonas vaginalis ap endonuclease, putative 0.0024 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Giardia lamblia DINP protein human, muc B family 0.0042 0.0085 0.0154
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0167 0.0538 0.2547
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0011 0.0057
Loa Loa (eye worm) hypothetical protein 0.023 0.0765 0.1475
Trypanosoma brucei unspecified product 0.0029 0.0037 0.0161
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0011 0.0002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0059 0.0147 0.0204
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.0199 0.0909
Echinococcus multilocularis importin subunit beta 1 0.0023 0.0017 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Schistosoma mansoni smad 0.0027 0.0028 0.0032
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0046 0.01 0.0431
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0064 0.0162 0.0162
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0021 0.001 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0087 0.0201
Toxoplasma gondii pyruvate kinase PyK1 0.0024 0.0018 0.0044
Trichomonas vaginalis ap endonuclease, putative 0.0024 0.0018 0.0041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0094 0.0271 0.0383
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0024 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0082 0.023 0.043
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0024 0.0018 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.016 0.0367
Entamoeba histolytica cysteine protease, putative 0.0094 0.0271 0.0623
Loa Loa (eye worm) hypothetical protein 0.0624 0.2191 0.4261
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0024 0.0018 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0212 0.0701 0.1263
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0047
Schistosoma mansoni cathepsin S (C01 family) 0.0094 0.0271 0.0383
Trypanosoma brucei glucosidase, putative 0.0109 0.0328 0.1809
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Echinococcus granulosus jumonji domain containing protein 0.0114 0.0346 0.0492
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0033 0.0062
Echinococcus multilocularis isocitrate dehydrogenase 0.0025 0.0023 0.0023
Onchocerca volvulus 0.0036 0.0064 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0073 0.0198 0.0905
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Echinococcus granulosus calpain A 0.0055 0.013 0.0179
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0497 0.1732 0.3122
Toxoplasma gondii PHD-finger domain-containing protein 0.0082 0.023 0.1243
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0047
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0027 0.003 0.0109
Mycobacterium ulcerans hypothetical protein 0.0074 0.0199 0.0909
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0064 0.0162 0.1392
Entamoeba histolytica hypothetical protein 0.0094 0.0271 0.0623
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0167 0.0538 0.2547
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0216
Echinococcus granulosus mothers against decapentaplegic 6 0.0027 0.0028 0.0032
Entamoeba histolytica hypothetical protein 0.0196 0.064 0.1476
Giardia lamblia Cysteine protease 0.0094 0.0271 0.0585
Onchocerca volvulus 0.007 0.0187 0.0437
Giardia lamblia Cathepsin B precursor 0.0094 0.0271 0.0585
Brugia malayi hypothetical protein 0.1552 0.5547 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0167 0.0538 0.2547
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0094 0.0271 0.2383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Loa Loa (eye worm) hypothetical protein 0.0046 0.01 0.0176
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0188 0.0614 0.3462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0765 0.1764
Schistosoma mansoni rab6-interacting 0.0028 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0243 0.0811 0.1566
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.001 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0328 0.0756
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0021
Giardia lamblia Cathepsin B precursor 0.0509 0.1773 0.4066
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.003 0.0041 0.0051
Loa Loa (eye worm) nuclear factor I 0.0033 0.0051 0.0081
Mycobacterium ulcerans pyruvate kinase 0.0024 0.0018 0.0038
Toxoplasma gondii ABC1 family protein 0.0034 0.0054 0.0248
Echinococcus granulosus importin subunit beta 1 0.0023 0.0017 0.0015
Brugia malayi chromobox protein homolog 3 0.0092 0.0266 0.0479
Entamoeba histolytica cysteine protease, putative 0.0094 0.0271 0.0623
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Loa Loa (eye worm) DR-78 0.01 0.0295 0.0557
Brugia malayi Heterochromatin protein 1 0.0164 0.0527 0.0951
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0094 0.0271 0.0383
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.01 0.0295 0.0702
Trypanosoma brucei polo-like protein kinase 0.0127 0.0391 0.2167
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.001 0.0005
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0094 0.0271 0.2383
Brugia malayi Papain family cysteine protease containing protein 0.0187 0.0608 0.1095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0212 0.0701 0.135
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0023 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0497 0.1732 0.1732
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0212 0.0701 0.1263
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Echinococcus multilocularis musashi 0.0049 0.0111 0.0111
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0021 0.001 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0054 0.04
Plasmodium falciparum thioredoxin reductase 0.0025 0.0024 0.0127
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Onchocerca volvulus 0.0049 0.0111 0.0249
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0127 0.039 0.039
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.0085 0.0194
Loa Loa (eye worm) Smad1 0.0059 0.0147 0.0268
Echinococcus granulosus cathepsin l1 0.023 0.0765 0.1099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Entamoeba histolytica cysteine proteinase, putative 0.0187 0.0608 0.1401
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0121 0.0531
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.003 0.0067
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.0076 0.0174
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Loa Loa (eye worm) steroid hormone receptor 0.0212 0.0701 0.135
Brugia malayi nuclear receptor RXR 0.01 0.0295 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0328 0.0639
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0458 0.159 0.3087
Trichomonas vaginalis mercuric reductase, putative 0.0025 0.0024 0.0055
Loa Loa (eye worm) hypothetical protein 0.0212 0.0701 0.135
Echinococcus granulosus phd:f box containing protein 0.0027 0.0028 0.0032
Brugia malayi CHD4 protein 0.0033 0.005 0.009
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Echinococcus multilocularis inositol monophosphatase 1 0.0028 0.0033 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Schistosoma mansoni hypothetical protein 0.0027 0.003 0.0034
Onchocerca volvulus 0.0027 0.003 0.005
Schistosoma mansoni lozenge 0.0078 0.0216 0.0303
Onchocerca volvulus 0.1017 0.3613 0.8878
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.01 0.0295 0.0531
Echinococcus multilocularis mothers against decapentaplegic 2 0.0027 0.0028 0.0028
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0765 0.1764
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0064 0.0162 0.1392
Plasmodium vivax hypothetical protein, conserved 0.0027 0.003 0.0175
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0121 0.0531
Entamoeba histolytica G protein alpha subunit, putative 0.0021 0.001 0.0021
Loa Loa (eye worm) hypothetical protein 0.0112 0.0338 0.0642
Giardia lamblia Cathepsin B precursor 0.0094 0.0271 0.0585
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Plasmodium falciparum basic transcription factor 3b, putative 0.005 0.0115 0.0953
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.051
Loa Loa (eye worm) hypothetical protein 0.0055 0.0132 0.0238
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0024 0.0018 0.0069
Loa Loa (eye worm) hypothetical protein 0.0048 0.0108 0.0191
Entamoeba histolytica hypothetical protein 0.005 0.0115 0.0263
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0248 0.0831 0.1604
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0079
Schistosoma mansoni hypothetical protein 0.1928 0.691 1
Entamoeba histolytica hypothetical protein 0.0196 0.064 0.1476
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0094 0.0271 0.0488
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0028 0.0037
Plasmodium falciparum phd finger protein, putative 0.0082 0.023 0.2008
Brugia malayi Papain family cysteine protease containing protein 0.0323 0.1102 0.1986
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0212 0.0701 0.1263
Schistosoma mansoni importin beta-1 0.0023 0.0017 0.0015
Echinococcus multilocularis cathepsin L 0.0187 0.0608 0.0607
Brugia malayi ecdysteroid receptor 0.0212 0.0701 0.1263
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0015 0.0013
Entamoeba histolytica hypothetical protein 0.0027 0.003 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0011 0.0019
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0094 0.0271 0.2383
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.051
Echinococcus granulosus lysine specific demethylase 5A 0.0105 0.0313 0.0444
Schistosoma mansoni cathepsin F (C01 family) 0.0323 0.1102 0.1587
Onchocerca volvulus 0.0034 0.0054 0.011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0028 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0033 0.0062
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0094 0.0271 0.0585
Plasmodium vivax thioredoxin reductase, putative 0.0073 0.0198 0.1718
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Giardia lamblia Hypothetical protein 0.0046 0.01 0.019
Plasmodium vivax importin-beta 2, putative 0.0023 0.0017 0.0054
Brugia malayi Muscleblind-like protein 0.0243 0.0811 0.1463
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1216 0.4334 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0027 0.003 0.0109
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0087
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0025 0.0024 0.0026
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0075 0.0203 0.0379
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0212 0.0701 0.1006
Loa Loa (eye worm) hypothetical protein 0.01 0.0295 0.0557
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0187 0.0608 0.1184
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0212 0.0701 0.1006
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0039
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0188 0.0614 0.1181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0212 0.0701 0.135
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0509 0.1773 0.4091
Brugia malayi Intermediate filament tail domain containing protein 0.0049 0.0111 0.02
Trypanosoma brucei trypanothione reductase 0.0073 0.0198 0.1072
Loa Loa (eye worm) glutaminase 2 0.0187 0.0611 0.1174
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0027 0.003 0.0117
Brugia malayi hypothetical protein 0.0099 0.0292 0.0527
Brugia malayi mbt repeat family protein 0.0034 0.0057 0.0103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0509 0.1773 0.2559
Trypanosoma cruzi cysteine peptidase, putative 0.0483 0.1678 0.3272
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.0271 0.0623
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0497 0.1732 0.2499
Loa Loa (eye worm) MH2 domain-containing protein 0.0871 0.3082 0.6003
Echinococcus multilocularis smad 0.0059 0.0147 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0212 0.0701 0.1263
Loa Loa (eye worm) hypothetical protein 0.0093 0.0269 0.0507
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.008 0.0183
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0028 0.0032
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0024 0.0018 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Echinococcus granulosus muscleblind protein 0.0243 0.0811 0.1166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Loa Loa (eye worm) hypothetical protein 0.0112 0.0338 0.0642
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1436 0.5129 0.7419
Loa Loa (eye worm) hypothetical protein 0.1143 0.4069 0.793
Brugia malayi TAR-binding protein 0.0458 0.159 0.2866
Brugia malayi Smad1 0.0059 0.0147 0.0265
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0085 0.0429
Brugia malayi Steroid receptor seven-up type 2 0.0212 0.0701 0.1263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0087 0.0201
Trypanosoma cruzi cysteine peptidase, putative 0.0093 0.0269 0.0524
Trypanosoma cruzi major cysteine proteinase, putative 0.0253 0.0847 0.1651
Echinococcus granulosus chromobox protein 1 0.0164 0.0527 0.0755
Plasmodium falciparum cysteine proteinase falcipain 3 0.0323 0.1102 1
Onchocerca volvulus Cathepsin L homolog 0.0094 0.0271 0.0643
Leishmania major cathepsin L-like protease 0.0323 0.1102 0.6213
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.001 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0105 0.0313 0.0444
Brugia malayi ecdysone receptor 0.01 0.0295 0.0531
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0127 0.0391 0.2204
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.008 0.0183
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0093 0.0269 0.0507
Echinococcus multilocularis lamin dm0 0.0049 0.0111 0.0111
Echinococcus granulosus Nuclear hormone receptor HR96 0.01 0.0295 0.0418
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0013 0.0012
Onchocerca volvulus Pyruvate kinase homolog 0.0024 0.0018 0.0022
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0094 0.0271 0.2383
Brugia malayi Associated with TFs and helicases family protein 0.0027 0.003 0.0054
Trypanosoma cruzi transcription factor btf3, putative 0.005 0.0115 0.0222
Toxoplasma gondii thioredoxin reductase 0.0073 0.0198 0.1063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Schistosoma mansoni blooms syndrome DNA helicase 0.0031 0.0046 0.0057
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0054 0.0128 0.0176
Trichomonas vaginalis hypothetical protein 0.0027 0.003 0.0067
Giardia lamblia Pyruvate kinase 0.0024 0.0018 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0135
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0132 0.1108
Mycobacterium ulcerans sulfatase 0.0046 0.01 0.0431
Loa Loa (eye worm) calpain family protein 1 0.0052 0.012 0.0216
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.0199 0.0909
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0028 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0092 0.0263 0.2317
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0021 0.001 0.0017
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0046 0.01 0.0431
Giardia lamblia Cysteine protease 0.0094 0.0271 0.0585
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0028 0.0028
Brugia malayi steroid hormone receptor 0.0212 0.0701 0.1263
Schistosoma mansoni steroid hormone receptor ad4bp 0.0212 0.0701 0.1006
Echinococcus multilocularis thyroid hormone receptor alpha 0.0212 0.0701 0.07
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.001 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.0271 0.0623
Echinococcus granulosus cysteine protease 0.0187 0.0608 0.0871
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0391 0.0902
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0057 0.0129
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0041 0.008 0.0173
Mycobacterium ulcerans arylsulfatase, AslA 0.0046 0.01 0.0431
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0323 0.1102 0.2542
Leishmania major pyruvate kinase 0.0024 0.0018 0.0101
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0132 0.1108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0087 0.0201
Echinococcus granulosus Nuclear hormone receptor HR96 0.01 0.0295 0.0418
Echinococcus granulosus neutral alpha glucosidase AB 0.0109 0.0328 0.0466
Entamoeba histolytica cysteine protease, putative 0.0187 0.0608 0.1401
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0167 0.0538 0.2547
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0144 0.0453 0.0453
Onchocerca volvulus 0.0323 0.1102 0.2691
Schistosoma mansoni nuclear hormone receptor 0.0212 0.0701 0.1006
Toxoplasma gondii LsmAD domain-containing protein 0.0092 0.0263 0.1435
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Onchocerca volvulus 0.0028 0.0035 0.0063
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.003 0.0107
Brugia malayi hypothetical protein 0.0059 0.0146 0.0263
Brugia malayi hypothetical protein 0.0112 0.0338 0.061
Echinococcus multilocularis PHD finger protein rhinoceros 0.0082 0.023 0.0229
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0034 0.0054 0.0211
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0024 0.0018 0.0017
Brugia malayi Cathepsin L-like precursor 0.0323 0.1102 0.1986
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0023 0.0126
Leishmania major cathepsin L-like protease 0.0323 0.1102 0.6213
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0127 0.0391 0.0391
Trypanosoma cruzi polo-like protein kinase, putative 0.0127 0.0391 0.0762
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0212 0.0701 0.1263
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0323 0.1102 1
Plasmodium falciparum serine repeat antigen 7 0.0094 0.0271 0.2383
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0894 0.3167 0.6168
Echinococcus granulosus tar DNA binding protein 0.0458 0.159 0.2294
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0188 0.0614 0.1107
Echinococcus multilocularis thioredoxin glutathione reductase 0.0074 0.02 0.0199
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0009 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0169 0.0388
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.005 0.005
Echinococcus multilocularis lipoxygenase domain containing protein 0.0028 0.0035 0.0035
Schistosoma mansoni chromobox protein 0.0164 0.0527 0.0755
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.01 0.0229
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0028 0.0037
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0187 0.0608 0.0871
Brugia malayi hypothetical protein 0.0192 0.0627 0.1131
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0037
Brugia malayi hypothetical protein 0.0057 0.014 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0169 0.0388
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0027 0.003 0.0034
Schistosoma mansoni cellular tumor antigen P53 0.007 0.0185 0.0258
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0216
Entamoeba histolytica cysteine protease, putative 0.0094 0.0271 0.0623
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.0085 0.0147
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0127 0.039 0.0556
Plasmodium falciparum serine repeat antigen 8 0.0094 0.0271 0.2383
Mycobacterium tuberculosis Probable lipase LipE 0.0034 0.0054 0.0211
Echinococcus multilocularis muscleblind protein 1 0.0243 0.0811 0.0811
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0094 0.0271 0.0383
Plasmodium vivax vivapain-2 0.0323 0.1102 1
Onchocerca volvulus 0.0323 0.1102 0.2691
Loa Loa (eye worm) MBCTL1 0.0039 0.0074 0.0126
Echinococcus granulosus expressed protein 0.0021 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0017
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.001 0.0005
Schistosoma mansoni kinase 0.0064 0.0166 0.0231
Brugia malayi MH2 domain containing protein 0.0059 0.0147 0.0265
Echinococcus granulosus geminin 0.1928 0.691 1
Plasmodium vivax hypothetical protein, conserved 0.0082 0.023 0.2008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0156 0.0499 0.0713
Schistosoma mansoni Smad4 0.0059 0.0147 0.0204
Loa Loa (eye worm) thioredoxin reductase 0.0073 0.0198 0.0368
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0199 0.0359
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0033 0.0074
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0085 0.0084
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0051
Plasmodium falciparum glutathione reductase 0.0025 0.0024 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0212 0.0701 0.135
Schistosoma mansoni rab6-interacting 0.0028 0.0035 0.0042
Brugia malayi RNA recognition motif domain containing protein 0.0458 0.159 0.2866
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0187 0.0608 0.1401
Loa Loa (eye worm) hypothetical protein 0.007 0.0185 0.0342
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0085 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0483 0.1678 0.9463
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0025 0.0024 0.0067
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0199 0.0654 0.0654
Echinococcus granulosus nuclear receptor 2DBD gamma 0.01 0.0295 0.0418
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0328 0.0756
Loa Loa (eye worm) hypothetical protein 0.0657 0.2309 0.4492
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0199 0.0359
Echinococcus multilocularis cysteine protease 0.0323 0.1102 0.1102
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0112 0.0338 0.0338
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0199 0.0909
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Echinococcus granulosus neuropeptide receptor A26 0.0382 0.1314 0.1895
Giardia lamblia Cathepsin L-like protease 0.0094 0.0271 0.0585
Brugia malayi Glycosyl hydrolases family 31 protein 0.0109 0.0328 0.0591
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0094 0.0271 0.0623
Onchocerca volvulus 0.0027 0.003 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0328 0.0756
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0092 0.0266 0.0631
Brugia malayi Papain family cysteine protease containing protein 0.0094 0.0271 0.0488
Brugia malayi Papain family cysteine protease containing protein 0.0094 0.0271 0.0488
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.001 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0087 0.0201
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0323 0.1102 0.2542
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0212 0.0701 0.07
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0109 0.0328 0.0756
Loa Loa (eye worm) hypothetical protein 0.0112 0.0338 0.0642
Loa Loa (eye worm) hypothetical protein 0.0055 0.0132 0.0238
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0094 0.0271 0.051
Entamoeba histolytica hypothetical protein 0.0196 0.064 0.1476
Trypanosoma cruzi major cysteine proteinase, putative 0.0094 0.0271 0.0527
Plasmodium falciparum serine repeat antigen 6 0.0094 0.0271 0.2383
Onchocerca volvulus 0.0022 0.0011 0.0002
Trichomonas vaginalis pyruvate kinase, putative 0.0024 0.0018 0.0041
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0075 0.0203 0.0286
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0031 0.0045 0.0316
Onchocerca volvulus 0.01 0.0295 0.0702
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0187 0.0608 0.0871
Leishmania major cathepsin L-like protease 0.0483 0.1678 0.9465
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0025 0.0023 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0199 0.1119
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0132 0.0584
Loa Loa (eye worm) hypothetical protein 0.0112 0.0338 0.0642
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0144 0.0453 0.0647
Brugia malayi serine/threonine-protein kinase plk-2 0.0127 0.0391 0.0705
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0188 0.0614 0.3431
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.003 0.0067
Echinococcus multilocularis cathepsin b 0.1436 0.5129 0.5129
Loa Loa (eye worm) nuclear hormone receptor 0.01 0.0295 0.0557
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0021 0.001 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0025 0.0024 0.0024
Echinococcus multilocularis nuclear receptor nhr 48 0.01 0.0295 0.0295
Toxoplasma gondii cathepsin CPC2 0.0094 0.0271 0.1476
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0085 0.0474
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0023 0.0079
Onchocerca volvulus 0.0323 0.1102 0.2691
Giardia lamblia Hypothetical protein 0.0094 0.0271 0.0585
Brugia malayi fibroinase precursor 0.0094 0.0271 0.0488
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0199 0.1119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0025 0.0024 0.0135
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0103 0.0526
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0112 0.0338 0.0642
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.01 0.0295 0.0418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0323 0.1102 0.2542
Brugia malayi Cathepsin L-like precursor 0.023 0.0765 0.1379
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.001 0.0005
Echinococcus granulosus smad 0.0059 0.0147 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0094 0.0271 0.0623
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0054 0.0128 0.0128
Plasmodium falciparum cysteine proteinase falcipain 1 0.0187 0.0608 0.5471

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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